table of contents of contents.pdf · biochim. biophys. acta 2014, 1837, 1208-1218 31 chapter 3...

2
Table of contents Chapter 1 General introduction 7 Chapter 2 ATP synthase in mycobacteria: special features and implications for a function as drug target Biochim. Biophys. Acta 2014, 1837, 1208-1218 31 Chapter 3 Pyrazinoic acid decreases the proton motive force, respiratory ATP synthesis activity, and cellular ATP levels .Antimicrob. Agents Chemother 2011, 55, 5354 – 5357 77 Chapter 4 In vitro synergy of bedaquiline and pyrazinoic acid Manuscript to be submitted 94 Chapter 5 The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis J. Antibiot. 2014,67, 835-837 110 Chapter 6 The role of cytochrome bd in Mycobacterium smegmatis in protection against reactive oxygen species and antibacterials . Article in preparation 121 Chapter 7 Summary and General discussion Addenda Samenvatting 166 摘要 171 Aknowledgement/ 致谢 174 Curriculum Vitae 176 Publication List 177

Upload: others

Post on 26-Jun-2020

4 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Table of contents of contents.pdf · Biochim. Biophys. Acta 2014, 1837, 1208-1218 31 Chapter 3 Pyrazinoic acid decreases the proton motive force, respiratory ATP synthesis activity,

Table of contents Chapter 1 General introduction 7 Chapter 2 ATP synthase in mycobacteria: special features and

implications for a function as drug target Biochim. Biophys. Acta 2014, 1837, 1208-1218 31

Chapter 3 Pyrazinoic acid decreases the proton motive force, respiratory ATP synthesis activity, and cellular ATP levels .Antimicrob. Agents Chemother 2011, 55, 5354 – 5357 77

Chapter 4 In vitro synergy of bedaquiline and pyrazinoic acid Manuscript to be submitted 94

Chapter 5 The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis J. Antibiot. 2014,67, 835-837 110

Chapter 6 The role of cytochrome bd in Mycobacterium smegmatis in protection against reactive oxygen species and antibacterials . Article in preparation 121

Chapter 7 Summary and General discussion Addenda Samenvatting 166

摘要 171 Aknowledgement/ 致谢 174 Curriculum Vitae 176 Publication List 177

 

Page 2: Table of contents of contents.pdf · Biochim. Biophys. Acta 2014, 1837, 1208-1218 31 Chapter 3 Pyrazinoic acid decreases the proton motive force, respiratory ATP synthesis activity,