suzette l. pereira, ph.d....suzette l. pereira- cv page 1 of 16 suzette l. pereira, ph.d. senior...

16
Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road, Columbus, OH 43219 Phone: 614-624-4625; Email- [email protected] ACADEMIC BACKGROUND Ph.D., Microbiology, 1997 OHIO STATE UNIVERSITY, Columbus, Ohio M.S., Microbiology, 1991 UNIVERSITY OF BOMBAY, Bombay (Mumbai), India B.S., Microbiology/Biochemistry, 1989 UNIVERSITY OF BOMBAY, Bombay (Mumbai), India PROFESSIONAL EXPERIENCE ABBOTT NUTRITION, Research & Development, Columbus, Ohio 2000-Present Sr. Ass. Research Fellow (2018- Present) Associate Research Fellow (2014- 2018) Sr. Research Scientist (2011-2014) Research Scientist (2007-2011) Senior Scientist (2004-2005) Scientist (2003-2004) Postdoctoral Fellow (2000-2003) THE OHIO STATE UNIVERSITY, Columbus, Ohio 2005-2007 Research Scientist (2005-2007) Consultant (2006-2007) THE OHIO STATE UNIVERSITY, Columbus, Ohio 1991-2000 Postdoctoral Fellow, Dept. of Microbiology (1998-2000) Graduate Student, Dept. of Microbiology (1991-1997) EXTERNAL ENGAGEMENT External Consortia 2016-Present: Serves on the industry advisory board for Aging in Motion (AIM) coalition- A multifaceted coalition responsible for obtaining the ICD-10 code for Sarcopenia.

Upload: others

Post on 16-Aug-2020

6 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 1 of 16

SUZETTE L PEREIRA PhD

SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition Strategic RampD

3300 Stelzer Road Columbus OH 43219 Phone 614-624-4625 Email- suzettepereiraabbottcom

ACADEMIC BACKGROUND PhD Microbiology 1997 OHIO STATE UNIVERSITY Columbus Ohio MS Microbiology 1991 UNIVERSITY OF BOMBAY Bombay (Mumbai) India BS MicrobiologyBiochemistry 1989 UNIVERSITY OF BOMBAY Bombay (Mumbai) India

PROFESSIONAL EXPERIENCE ABBOTT NUTRITION Research amp Development Columbus Ohio 2000-Present Sr Ass Research Fellow (2018- Present) Associate Research Fellow (2014- 2018) Sr Research Scientist (2011-2014) Research Scientist (2007-2011) Senior Scientist (2004-2005) Scientist (2003-2004) Postdoctoral Fellow (2000-2003) THE OHIO STATE UNIVERSITY Columbus Ohio 2005-2007 Research Scientist (2005-2007) Consultant (2006-2007) THE OHIO STATE UNIVERSITY Columbus Ohio 1991-2000 Postdoctoral Fellow Dept of Microbiology (1998-2000) Graduate Student Dept of Microbiology (1991-1997)

EXTERNAL ENGAGEMENT External Consortia 2016-Present Serves on the industry advisory board for Aging in Motion (AIM) coalition- A

multifaceted coalition responsible for obtaining the ICD-10 code for Sarcopenia

Suzette L Pereira- CV Page 2 of 16

2010- 2018 Abbott representative to lsquoFoundation of the NIH (FNIH)-Sarcopenia Biomarker Consortiumrsquo a consortium dedicated to developing a data-driven consensus guideline for the diagnosis of sarcopenia

Round TablesExpert PanelsSymposia 2019

bull Served on the Organizing Committee for European Society for Parenteral and Enteral Nutrition (ESPEN)-Abbott Nutrition Health Institute (ANHI) symposium entitled lsquoImproving Patient Outcomes New Insights and Evidence on the Importance of Muscle and Targeted Nutritionrsquo held on August 31 2019

bull Served of the Organizing Committee for ANHI Adult Nutrition Scientific Roundtable entitled lsquoThe role of nutrition therapy across the continuum of care 2020 insightrsquo held on Nov 7 2019

2018

bull Chaired the round table event hosted by The Atlantic and Abbott Public Affairs in NYC with discussion centered around lsquoMeaningful ways to measure health as we age- with a focus on musclersquo

bull Served on Abbott Nutrition (AN) Steering committee for development of the Strength Ambassador program held at ASPEN

bull Invited panelist at the 2018 International Conference on Frailty and Sarcopenia research (ICFSR) Task Force on topic lsquoDrug and Nutrition Trials for Frailty and Sarcopenia Managing Sarcopeniarsquo

bull Invited panelist for 2018 Position Development Conference of the Sarcopenia Definitions and Outcomes-Sarcopenia Consortium

2017

bull Invited panelist on the FNIH-Sarcopenia Consortium annual meeting to discuss the implications of the ICD10 code for sarcopenia

bull Invited participant in the ICSFR Task Force panel on lsquoImplication of ICD 10 code for sarcopenia in clinical practice and randomized controlled trialsrsquo

bull Co-organized and participant at the AN-sponsored round table post-ICFSR towards the development of manuscript describing the importance of muscle loss in malnutrition

2016

bull Co-organized an Abbott-sponsored symposium entitled lsquoRole of Beta-hydroxy-beta-methylbutyrate (HMB) in preserving musclersquo at the 9th International Conference on Cachexia Sarcopenia and Muscle Wasting

bull Invited participant in Abbott Nutrition Health Institute (ANHI) Roundtable lsquoNew Advances of Food Science in Clinical Nutritionrsquo (Chicago June 7th)

bull Co-organized and moderator at the Abbott Nutrition Health Institute (ANHI) Roundtable lsquoAssessing Clinical Utility of Malnutrition Biomarkersrsquo (Chicago June 7th)

2015

bull Co-organizer and participant in the Abbott sponsored lsquoNutrition Education for Physiciansrsquo Advisory Board to discuss topics related to opportunities for the use of a blood-based malnutrition diagnostic in hospital setting (Los Angeles February 13 2015)

bull Invited participant in lsquoFNIH-Kids Thrive Healthy Children Through Healthy Behaviorsrsquo Executive and scientific advisory committee meeting held in NY on February 10 2015

Suzette L Pereira- CV Page 3 of 16

bull Invited participant in New York Academy of Science (NYAS)-Sackler round table meeting entitled lsquoHuman and Environmental factors contributing to Malnutrition in India Implications for Nutritional Interventionsrsquo (May 2015)

2012

bull Invited panelist for the New York Academy of Science (NYAS)- Sackler workshop entitled lsquoBiomarkers in Nutritionrsquo (NY April 18 2012)

2010

bull Steering committee member for the ANHI-sponsored lsquo111th Inflammation and Nutrition in Chronic Diseasersquo (Columbus April 2010)

Public Affairs 2020

bull Abbott Nutrition Health Institute podcast series related to COVID-19 and importance of muscle httpsanhiorgresourcespodcasts-and-videosmuscle-mass-hmb-and-covid-19

bull 2 media podcasts recorded

bull 1 media article by US News and World Report httpshealthusnewscomhealth-carepatient-advicearticleshow-to-regain-strength-after-covid-19

2019

bull 2 media articles based on live interviews related to the important role of muscle for health httpswwwnaturalproductsinsidercomhealthy-livingoutmuscling-sarcopenia httpsthedoctorweighsincomwhen-it-comes-to-health-muscle-mass-matters

2018

bull 3 live radio interviews with media from Sirius WebMD NPR-Radio Radio MD httpradiomdcomshowlifes-too-shortitem38589-muscle-mass-a-factor-in-healing httpitsyourhealthwithlisadaviscom18143-2

bull Interviewed in a Satellite Media Tour (SMT) with 18-media outlets to discuss the importance of protein for muscle health

bull 5 media interviews resulting in media articles httpswwwthehealthycomaginghealthy-agingsigns-body-is-aging-faster-than-you httpswwwfoodnavigator-usacomArticle20180227Sarcopenia-is-the-new-osteoporosis-Abbott-continues-to-explore-solutions-to-counter-muscle lossutm_source=RSS_Feedamputm_medium=RSSamputm_campaign=RSS httpshealthusnewscomwellnessfoodarticles2018-03-30older-adults-dont-get-enough-of-this-important-nutrient

2017

bull 8 media interviews organized by Abbott Public Affairs related to the importance of muscle in health and how to prevent loss of muscle Media included The Atlantic Fox News Health NY times Health Readers Digest and resulted in media articles citing Abbott scientists httpwwwfoxnewscomlifestyle20170501how-to-prevent-muscle-loss-as-agehtml httpswwwtheatlanticcomsponsoredensure-2017is-it-time-to-move-on-from-bmi1353 httpswwwbustlecomp9-things-that-can-cause-you-to-lose-muscle-according-to-experts-44863 httpswwwrdcomhealthdiet-weight-lossthings-cause-you-to-lose-muscle

2016

Suzette L Pereira- CV Page 4 of 16

bull 1 media interview with reporter from Next Avenue a PBS-owned site related to muscle loss in women over 50 years httpswwwnextavenueorgbody-changes-50-control

EXTERNAL INVITED PRESENTATIONS

1 Invited Moderator at ICFSR Conference- Sessions Conference 11-13 Oral communication 27-31 (2019)

2 ICFSR Sarcopenia Task Force meeting- Invited Panel Speaker- Topicrsquo Nutrition Interventions for Sarcopeniarsquo (2018)

3 Served as Expert panelist at the FNIH Sarcopenia Biomarker consortium (SDOC) meeting (2018)

4 Speaker for the Aging in Motion (AIM) Coalition Webinar series lsquoICD-10 code for Sarcopeniarsquo (2017)

5 Speaker at the lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo Conference (Univ Florida) Title of talk was lsquoRole of HMB in addressing age-related muscle lossrsquo (2017)

6 Speaker at the lsquoNIH workshop- Emerging role of BCAA in Human Diseasesrsquo and gave a presentation entitled lsquoRole of HMB in Attenuating Muscle Lossrsquo (2017)

7 Speaker at the ANHI-Satellite symposium at ESPEN Title lsquoImproving Clinical Outcomes by Supporting Muscle Why it matters for your patientsrsquo (2017)

8 Speaker for a Webinar for Ireland dietitians Specialized Nutrition The Key To Promoting Lean Body Mass To Optimize Recoveryrsquo (2017)

9 Speaker at the AN-sponsored Symposium at FNCE entitled lsquoTrends in Lean Body Mass Identify Intervene Innovatersquo (2015)

10 Selected oral presentation- Novel Serum Biomarkers that Predict Sarcopenia in Older Malnourished Men International Conference of Frailty and Sarcopenia Research (ICFSR) (2015)

11 Selected oral presentation The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia International Conference of Frailty and Sarcopenia Research (ICFSR)- J Frailty Aging (2014) 3 (1) p 39

12 Speaker at the Bowling Green State University Nutrition Symposium Title Sarcopenic obesity Recognizing the hidden enemyrsquo (2013)

13 Speaker at EUUS Task Force on designing drug trials for sarcopenia in frail older adults Title LBM loss in a Bed Rest model Satellite Symposium at International Conference of Frailty and Sarcopenia Research (ICFSR) (2012)

14 Selected oral presentation Effects of HMB on muscle recovery following hind limb suspension in aged rats 5th Cachexia Conference Barcelona Spain (2005)

15 Speaker at the 95th American Oil Chemical Society Meeting Topic Omega-3 fatty acids and cancer cachexia (2004)

16 Selected oral presentation A novel fungal omega-3 desaturase involved in Eicosapentaenoic acid (EPA) production National Plant Lipid Cooperative (NPLC) (2003)

Suzette L Pereira- CV Page 5 of 16

ABBOTT-SPONSORED EXTERNAL PRESENTATIONS 1 Invited speaker at the lsquoCumbre Nacional de Nutrićionrsquo in Colombia (April 5-6 2019) Title

lsquoProtein and HMB The science behind those interesting ingredientsrsquo 2 Invited speaker at the ESPEN 2019 Strength Ambassador Program- Title Nutrition-Focus on

Protein and HMBrsquo 3 Invited speaker at the Turkey KOL meeting at ASPEN 2018 (coordinated by ANI Turkey affiliate)

Topic Loss of Lean Mass- The New Malnutrition 4 Invited speaker at the Strength Ambassador program ESPEN 2018 Topic The Importance of

Muscle and Targeted Nutrition across the Continuum of Care 5 Moderator at ESPEN ANHI-sponsored symposium ESPEN 2018 Topic Nutritional Strategies to

tackle loss of muscle mass and improve patient outcomes across the healthcare continuum 6 Invited speaker at the ANI-Strength Ambassador program held during ESPEN 2017 Topic Loss

of Lean mass The new malnutrition 7 Invited speaker at ANI symposium at Clinical Nutrition Week (Clinical Nutrition Week-ASPEN

2016)- Topic lsquoSpecialized Nutrition The key to maintaining LBM to optimize recoveryrsquo 8 Volwiler Seminar Series Oral presentation (2016) Topic lsquoAddressing Age-Related Muscle Loss

and Weakness Current Approaches and Future Strategiesrsquo 9 Invited speaker to Abbott Nutrition Science Seminar Series (NSSS)- Latin America Sept 26th

2013 Topic Scientific Background of HMBrsquo 10 Effect of HMB on Muscle during Extended Bed Rest in the Elderly (2012) Oral Presentation at

the lsquoMeet the Nutrition Expertrsquo session- ESPEN 2012 (Barcelona Spain)

PATENTS GRANTED 2019

1 EP2672843B1 Nutritional products comprising beta-hydroxy-beta-methylbutyrate 2018

2 US10058113B2 Shelf-stable clear liquid Nutritional compositions comprising Epigallocatechin gallate (EGCg) and methods for preparing the same

3 US9844531 Method of maintaining and improving muscle function 2017

4 US9579347B2 Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss 5 US9675097B2 Shelf Stable clear liquid nutritional composition comprising Epigallocatechin

gallate (EGCg) and methods for preparing the same 6 US9713598B2 Treatment of Insulin Resistance Associated with Prolonged Physical Activity 7 US9844531B2 Method of maintaining and improving muscle function

2014 8 US8916361B2 Elongase gene and uses thereof 9 US8916154B2 Antibodies against delta-5 desaturase and uses thereof 10 EP1507855B2 Elongase genes and uses thereof 11 US8778632B2 Δ6-desaturase genes and uses thereof 12 EP2358869B1 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2013 13 EP2333052B1 Desaturase genes and uses thereof 14 EP2325300B1 Desaturase genes and uses thereof

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 2: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 2 of 16

2010- 2018 Abbott representative to lsquoFoundation of the NIH (FNIH)-Sarcopenia Biomarker Consortiumrsquo a consortium dedicated to developing a data-driven consensus guideline for the diagnosis of sarcopenia

Round TablesExpert PanelsSymposia 2019

bull Served on the Organizing Committee for European Society for Parenteral and Enteral Nutrition (ESPEN)-Abbott Nutrition Health Institute (ANHI) symposium entitled lsquoImproving Patient Outcomes New Insights and Evidence on the Importance of Muscle and Targeted Nutritionrsquo held on August 31 2019

bull Served of the Organizing Committee for ANHI Adult Nutrition Scientific Roundtable entitled lsquoThe role of nutrition therapy across the continuum of care 2020 insightrsquo held on Nov 7 2019

2018

bull Chaired the round table event hosted by The Atlantic and Abbott Public Affairs in NYC with discussion centered around lsquoMeaningful ways to measure health as we age- with a focus on musclersquo

bull Served on Abbott Nutrition (AN) Steering committee for development of the Strength Ambassador program held at ASPEN

bull Invited panelist at the 2018 International Conference on Frailty and Sarcopenia research (ICFSR) Task Force on topic lsquoDrug and Nutrition Trials for Frailty and Sarcopenia Managing Sarcopeniarsquo

bull Invited panelist for 2018 Position Development Conference of the Sarcopenia Definitions and Outcomes-Sarcopenia Consortium

2017

bull Invited panelist on the FNIH-Sarcopenia Consortium annual meeting to discuss the implications of the ICD10 code for sarcopenia

bull Invited participant in the ICSFR Task Force panel on lsquoImplication of ICD 10 code for sarcopenia in clinical practice and randomized controlled trialsrsquo

bull Co-organized and participant at the AN-sponsored round table post-ICFSR towards the development of manuscript describing the importance of muscle loss in malnutrition

2016

bull Co-organized an Abbott-sponsored symposium entitled lsquoRole of Beta-hydroxy-beta-methylbutyrate (HMB) in preserving musclersquo at the 9th International Conference on Cachexia Sarcopenia and Muscle Wasting

bull Invited participant in Abbott Nutrition Health Institute (ANHI) Roundtable lsquoNew Advances of Food Science in Clinical Nutritionrsquo (Chicago June 7th)

bull Co-organized and moderator at the Abbott Nutrition Health Institute (ANHI) Roundtable lsquoAssessing Clinical Utility of Malnutrition Biomarkersrsquo (Chicago June 7th)

2015

bull Co-organizer and participant in the Abbott sponsored lsquoNutrition Education for Physiciansrsquo Advisory Board to discuss topics related to opportunities for the use of a blood-based malnutrition diagnostic in hospital setting (Los Angeles February 13 2015)

bull Invited participant in lsquoFNIH-Kids Thrive Healthy Children Through Healthy Behaviorsrsquo Executive and scientific advisory committee meeting held in NY on February 10 2015

Suzette L Pereira- CV Page 3 of 16

bull Invited participant in New York Academy of Science (NYAS)-Sackler round table meeting entitled lsquoHuman and Environmental factors contributing to Malnutrition in India Implications for Nutritional Interventionsrsquo (May 2015)

2012

bull Invited panelist for the New York Academy of Science (NYAS)- Sackler workshop entitled lsquoBiomarkers in Nutritionrsquo (NY April 18 2012)

2010

bull Steering committee member for the ANHI-sponsored lsquo111th Inflammation and Nutrition in Chronic Diseasersquo (Columbus April 2010)

Public Affairs 2020

bull Abbott Nutrition Health Institute podcast series related to COVID-19 and importance of muscle httpsanhiorgresourcespodcasts-and-videosmuscle-mass-hmb-and-covid-19

bull 2 media podcasts recorded

bull 1 media article by US News and World Report httpshealthusnewscomhealth-carepatient-advicearticleshow-to-regain-strength-after-covid-19

2019

bull 2 media articles based on live interviews related to the important role of muscle for health httpswwwnaturalproductsinsidercomhealthy-livingoutmuscling-sarcopenia httpsthedoctorweighsincomwhen-it-comes-to-health-muscle-mass-matters

2018

bull 3 live radio interviews with media from Sirius WebMD NPR-Radio Radio MD httpradiomdcomshowlifes-too-shortitem38589-muscle-mass-a-factor-in-healing httpitsyourhealthwithlisadaviscom18143-2

bull Interviewed in a Satellite Media Tour (SMT) with 18-media outlets to discuss the importance of protein for muscle health

bull 5 media interviews resulting in media articles httpswwwthehealthycomaginghealthy-agingsigns-body-is-aging-faster-than-you httpswwwfoodnavigator-usacomArticle20180227Sarcopenia-is-the-new-osteoporosis-Abbott-continues-to-explore-solutions-to-counter-muscle lossutm_source=RSS_Feedamputm_medium=RSSamputm_campaign=RSS httpshealthusnewscomwellnessfoodarticles2018-03-30older-adults-dont-get-enough-of-this-important-nutrient

2017

bull 8 media interviews organized by Abbott Public Affairs related to the importance of muscle in health and how to prevent loss of muscle Media included The Atlantic Fox News Health NY times Health Readers Digest and resulted in media articles citing Abbott scientists httpwwwfoxnewscomlifestyle20170501how-to-prevent-muscle-loss-as-agehtml httpswwwtheatlanticcomsponsoredensure-2017is-it-time-to-move-on-from-bmi1353 httpswwwbustlecomp9-things-that-can-cause-you-to-lose-muscle-according-to-experts-44863 httpswwwrdcomhealthdiet-weight-lossthings-cause-you-to-lose-muscle

2016

Suzette L Pereira- CV Page 4 of 16

bull 1 media interview with reporter from Next Avenue a PBS-owned site related to muscle loss in women over 50 years httpswwwnextavenueorgbody-changes-50-control

EXTERNAL INVITED PRESENTATIONS

1 Invited Moderator at ICFSR Conference- Sessions Conference 11-13 Oral communication 27-31 (2019)

2 ICFSR Sarcopenia Task Force meeting- Invited Panel Speaker- Topicrsquo Nutrition Interventions for Sarcopeniarsquo (2018)

3 Served as Expert panelist at the FNIH Sarcopenia Biomarker consortium (SDOC) meeting (2018)

4 Speaker for the Aging in Motion (AIM) Coalition Webinar series lsquoICD-10 code for Sarcopeniarsquo (2017)

5 Speaker at the lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo Conference (Univ Florida) Title of talk was lsquoRole of HMB in addressing age-related muscle lossrsquo (2017)

6 Speaker at the lsquoNIH workshop- Emerging role of BCAA in Human Diseasesrsquo and gave a presentation entitled lsquoRole of HMB in Attenuating Muscle Lossrsquo (2017)

7 Speaker at the ANHI-Satellite symposium at ESPEN Title lsquoImproving Clinical Outcomes by Supporting Muscle Why it matters for your patientsrsquo (2017)

8 Speaker for a Webinar for Ireland dietitians Specialized Nutrition The Key To Promoting Lean Body Mass To Optimize Recoveryrsquo (2017)

9 Speaker at the AN-sponsored Symposium at FNCE entitled lsquoTrends in Lean Body Mass Identify Intervene Innovatersquo (2015)

10 Selected oral presentation- Novel Serum Biomarkers that Predict Sarcopenia in Older Malnourished Men International Conference of Frailty and Sarcopenia Research (ICFSR) (2015)

11 Selected oral presentation The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia International Conference of Frailty and Sarcopenia Research (ICFSR)- J Frailty Aging (2014) 3 (1) p 39

12 Speaker at the Bowling Green State University Nutrition Symposium Title Sarcopenic obesity Recognizing the hidden enemyrsquo (2013)

13 Speaker at EUUS Task Force on designing drug trials for sarcopenia in frail older adults Title LBM loss in a Bed Rest model Satellite Symposium at International Conference of Frailty and Sarcopenia Research (ICFSR) (2012)

14 Selected oral presentation Effects of HMB on muscle recovery following hind limb suspension in aged rats 5th Cachexia Conference Barcelona Spain (2005)

15 Speaker at the 95th American Oil Chemical Society Meeting Topic Omega-3 fatty acids and cancer cachexia (2004)

16 Selected oral presentation A novel fungal omega-3 desaturase involved in Eicosapentaenoic acid (EPA) production National Plant Lipid Cooperative (NPLC) (2003)

Suzette L Pereira- CV Page 5 of 16

ABBOTT-SPONSORED EXTERNAL PRESENTATIONS 1 Invited speaker at the lsquoCumbre Nacional de Nutrićionrsquo in Colombia (April 5-6 2019) Title

lsquoProtein and HMB The science behind those interesting ingredientsrsquo 2 Invited speaker at the ESPEN 2019 Strength Ambassador Program- Title Nutrition-Focus on

Protein and HMBrsquo 3 Invited speaker at the Turkey KOL meeting at ASPEN 2018 (coordinated by ANI Turkey affiliate)

Topic Loss of Lean Mass- The New Malnutrition 4 Invited speaker at the Strength Ambassador program ESPEN 2018 Topic The Importance of

Muscle and Targeted Nutrition across the Continuum of Care 5 Moderator at ESPEN ANHI-sponsored symposium ESPEN 2018 Topic Nutritional Strategies to

tackle loss of muscle mass and improve patient outcomes across the healthcare continuum 6 Invited speaker at the ANI-Strength Ambassador program held during ESPEN 2017 Topic Loss

of Lean mass The new malnutrition 7 Invited speaker at ANI symposium at Clinical Nutrition Week (Clinical Nutrition Week-ASPEN

2016)- Topic lsquoSpecialized Nutrition The key to maintaining LBM to optimize recoveryrsquo 8 Volwiler Seminar Series Oral presentation (2016) Topic lsquoAddressing Age-Related Muscle Loss

and Weakness Current Approaches and Future Strategiesrsquo 9 Invited speaker to Abbott Nutrition Science Seminar Series (NSSS)- Latin America Sept 26th

2013 Topic Scientific Background of HMBrsquo 10 Effect of HMB on Muscle during Extended Bed Rest in the Elderly (2012) Oral Presentation at

the lsquoMeet the Nutrition Expertrsquo session- ESPEN 2012 (Barcelona Spain)

PATENTS GRANTED 2019

1 EP2672843B1 Nutritional products comprising beta-hydroxy-beta-methylbutyrate 2018

2 US10058113B2 Shelf-stable clear liquid Nutritional compositions comprising Epigallocatechin gallate (EGCg) and methods for preparing the same

3 US9844531 Method of maintaining and improving muscle function 2017

4 US9579347B2 Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss 5 US9675097B2 Shelf Stable clear liquid nutritional composition comprising Epigallocatechin

gallate (EGCg) and methods for preparing the same 6 US9713598B2 Treatment of Insulin Resistance Associated with Prolonged Physical Activity 7 US9844531B2 Method of maintaining and improving muscle function

2014 8 US8916361B2 Elongase gene and uses thereof 9 US8916154B2 Antibodies against delta-5 desaturase and uses thereof 10 EP1507855B2 Elongase genes and uses thereof 11 US8778632B2 Δ6-desaturase genes and uses thereof 12 EP2358869B1 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2013 13 EP2333052B1 Desaturase genes and uses thereof 14 EP2325300B1 Desaturase genes and uses thereof

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 3: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 3 of 16

bull Invited participant in New York Academy of Science (NYAS)-Sackler round table meeting entitled lsquoHuman and Environmental factors contributing to Malnutrition in India Implications for Nutritional Interventionsrsquo (May 2015)

2012

bull Invited panelist for the New York Academy of Science (NYAS)- Sackler workshop entitled lsquoBiomarkers in Nutritionrsquo (NY April 18 2012)

2010

bull Steering committee member for the ANHI-sponsored lsquo111th Inflammation and Nutrition in Chronic Diseasersquo (Columbus April 2010)

Public Affairs 2020

bull Abbott Nutrition Health Institute podcast series related to COVID-19 and importance of muscle httpsanhiorgresourcespodcasts-and-videosmuscle-mass-hmb-and-covid-19

bull 2 media podcasts recorded

bull 1 media article by US News and World Report httpshealthusnewscomhealth-carepatient-advicearticleshow-to-regain-strength-after-covid-19

2019

bull 2 media articles based on live interviews related to the important role of muscle for health httpswwwnaturalproductsinsidercomhealthy-livingoutmuscling-sarcopenia httpsthedoctorweighsincomwhen-it-comes-to-health-muscle-mass-matters

2018

bull 3 live radio interviews with media from Sirius WebMD NPR-Radio Radio MD httpradiomdcomshowlifes-too-shortitem38589-muscle-mass-a-factor-in-healing httpitsyourhealthwithlisadaviscom18143-2

bull Interviewed in a Satellite Media Tour (SMT) with 18-media outlets to discuss the importance of protein for muscle health

bull 5 media interviews resulting in media articles httpswwwthehealthycomaginghealthy-agingsigns-body-is-aging-faster-than-you httpswwwfoodnavigator-usacomArticle20180227Sarcopenia-is-the-new-osteoporosis-Abbott-continues-to-explore-solutions-to-counter-muscle lossutm_source=RSS_Feedamputm_medium=RSSamputm_campaign=RSS httpshealthusnewscomwellnessfoodarticles2018-03-30older-adults-dont-get-enough-of-this-important-nutrient

2017

bull 8 media interviews organized by Abbott Public Affairs related to the importance of muscle in health and how to prevent loss of muscle Media included The Atlantic Fox News Health NY times Health Readers Digest and resulted in media articles citing Abbott scientists httpwwwfoxnewscomlifestyle20170501how-to-prevent-muscle-loss-as-agehtml httpswwwtheatlanticcomsponsoredensure-2017is-it-time-to-move-on-from-bmi1353 httpswwwbustlecomp9-things-that-can-cause-you-to-lose-muscle-according-to-experts-44863 httpswwwrdcomhealthdiet-weight-lossthings-cause-you-to-lose-muscle

2016

Suzette L Pereira- CV Page 4 of 16

bull 1 media interview with reporter from Next Avenue a PBS-owned site related to muscle loss in women over 50 years httpswwwnextavenueorgbody-changes-50-control

EXTERNAL INVITED PRESENTATIONS

1 Invited Moderator at ICFSR Conference- Sessions Conference 11-13 Oral communication 27-31 (2019)

2 ICFSR Sarcopenia Task Force meeting- Invited Panel Speaker- Topicrsquo Nutrition Interventions for Sarcopeniarsquo (2018)

3 Served as Expert panelist at the FNIH Sarcopenia Biomarker consortium (SDOC) meeting (2018)

4 Speaker for the Aging in Motion (AIM) Coalition Webinar series lsquoICD-10 code for Sarcopeniarsquo (2017)

5 Speaker at the lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo Conference (Univ Florida) Title of talk was lsquoRole of HMB in addressing age-related muscle lossrsquo (2017)

6 Speaker at the lsquoNIH workshop- Emerging role of BCAA in Human Diseasesrsquo and gave a presentation entitled lsquoRole of HMB in Attenuating Muscle Lossrsquo (2017)

7 Speaker at the ANHI-Satellite symposium at ESPEN Title lsquoImproving Clinical Outcomes by Supporting Muscle Why it matters for your patientsrsquo (2017)

8 Speaker for a Webinar for Ireland dietitians Specialized Nutrition The Key To Promoting Lean Body Mass To Optimize Recoveryrsquo (2017)

9 Speaker at the AN-sponsored Symposium at FNCE entitled lsquoTrends in Lean Body Mass Identify Intervene Innovatersquo (2015)

10 Selected oral presentation- Novel Serum Biomarkers that Predict Sarcopenia in Older Malnourished Men International Conference of Frailty and Sarcopenia Research (ICFSR) (2015)

11 Selected oral presentation The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia International Conference of Frailty and Sarcopenia Research (ICFSR)- J Frailty Aging (2014) 3 (1) p 39

12 Speaker at the Bowling Green State University Nutrition Symposium Title Sarcopenic obesity Recognizing the hidden enemyrsquo (2013)

13 Speaker at EUUS Task Force on designing drug trials for sarcopenia in frail older adults Title LBM loss in a Bed Rest model Satellite Symposium at International Conference of Frailty and Sarcopenia Research (ICFSR) (2012)

14 Selected oral presentation Effects of HMB on muscle recovery following hind limb suspension in aged rats 5th Cachexia Conference Barcelona Spain (2005)

15 Speaker at the 95th American Oil Chemical Society Meeting Topic Omega-3 fatty acids and cancer cachexia (2004)

16 Selected oral presentation A novel fungal omega-3 desaturase involved in Eicosapentaenoic acid (EPA) production National Plant Lipid Cooperative (NPLC) (2003)

Suzette L Pereira- CV Page 5 of 16

ABBOTT-SPONSORED EXTERNAL PRESENTATIONS 1 Invited speaker at the lsquoCumbre Nacional de Nutrićionrsquo in Colombia (April 5-6 2019) Title

lsquoProtein and HMB The science behind those interesting ingredientsrsquo 2 Invited speaker at the ESPEN 2019 Strength Ambassador Program- Title Nutrition-Focus on

Protein and HMBrsquo 3 Invited speaker at the Turkey KOL meeting at ASPEN 2018 (coordinated by ANI Turkey affiliate)

Topic Loss of Lean Mass- The New Malnutrition 4 Invited speaker at the Strength Ambassador program ESPEN 2018 Topic The Importance of

Muscle and Targeted Nutrition across the Continuum of Care 5 Moderator at ESPEN ANHI-sponsored symposium ESPEN 2018 Topic Nutritional Strategies to

tackle loss of muscle mass and improve patient outcomes across the healthcare continuum 6 Invited speaker at the ANI-Strength Ambassador program held during ESPEN 2017 Topic Loss

of Lean mass The new malnutrition 7 Invited speaker at ANI symposium at Clinical Nutrition Week (Clinical Nutrition Week-ASPEN

2016)- Topic lsquoSpecialized Nutrition The key to maintaining LBM to optimize recoveryrsquo 8 Volwiler Seminar Series Oral presentation (2016) Topic lsquoAddressing Age-Related Muscle Loss

and Weakness Current Approaches and Future Strategiesrsquo 9 Invited speaker to Abbott Nutrition Science Seminar Series (NSSS)- Latin America Sept 26th

2013 Topic Scientific Background of HMBrsquo 10 Effect of HMB on Muscle during Extended Bed Rest in the Elderly (2012) Oral Presentation at

the lsquoMeet the Nutrition Expertrsquo session- ESPEN 2012 (Barcelona Spain)

PATENTS GRANTED 2019

1 EP2672843B1 Nutritional products comprising beta-hydroxy-beta-methylbutyrate 2018

2 US10058113B2 Shelf-stable clear liquid Nutritional compositions comprising Epigallocatechin gallate (EGCg) and methods for preparing the same

3 US9844531 Method of maintaining and improving muscle function 2017

4 US9579347B2 Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss 5 US9675097B2 Shelf Stable clear liquid nutritional composition comprising Epigallocatechin

gallate (EGCg) and methods for preparing the same 6 US9713598B2 Treatment of Insulin Resistance Associated with Prolonged Physical Activity 7 US9844531B2 Method of maintaining and improving muscle function

2014 8 US8916361B2 Elongase gene and uses thereof 9 US8916154B2 Antibodies against delta-5 desaturase and uses thereof 10 EP1507855B2 Elongase genes and uses thereof 11 US8778632B2 Δ6-desaturase genes and uses thereof 12 EP2358869B1 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2013 13 EP2333052B1 Desaturase genes and uses thereof 14 EP2325300B1 Desaturase genes and uses thereof

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 4: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 4 of 16

bull 1 media interview with reporter from Next Avenue a PBS-owned site related to muscle loss in women over 50 years httpswwwnextavenueorgbody-changes-50-control

EXTERNAL INVITED PRESENTATIONS

1 Invited Moderator at ICFSR Conference- Sessions Conference 11-13 Oral communication 27-31 (2019)

2 ICFSR Sarcopenia Task Force meeting- Invited Panel Speaker- Topicrsquo Nutrition Interventions for Sarcopeniarsquo (2018)

3 Served as Expert panelist at the FNIH Sarcopenia Biomarker consortium (SDOC) meeting (2018)

4 Speaker for the Aging in Motion (AIM) Coalition Webinar series lsquoICD-10 code for Sarcopeniarsquo (2017)

5 Speaker at the lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo Conference (Univ Florida) Title of talk was lsquoRole of HMB in addressing age-related muscle lossrsquo (2017)

6 Speaker at the lsquoNIH workshop- Emerging role of BCAA in Human Diseasesrsquo and gave a presentation entitled lsquoRole of HMB in Attenuating Muscle Lossrsquo (2017)

7 Speaker at the ANHI-Satellite symposium at ESPEN Title lsquoImproving Clinical Outcomes by Supporting Muscle Why it matters for your patientsrsquo (2017)

8 Speaker for a Webinar for Ireland dietitians Specialized Nutrition The Key To Promoting Lean Body Mass To Optimize Recoveryrsquo (2017)

9 Speaker at the AN-sponsored Symposium at FNCE entitled lsquoTrends in Lean Body Mass Identify Intervene Innovatersquo (2015)

10 Selected oral presentation- Novel Serum Biomarkers that Predict Sarcopenia in Older Malnourished Men International Conference of Frailty and Sarcopenia Research (ICFSR) (2015)

11 Selected oral presentation The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia International Conference of Frailty and Sarcopenia Research (ICFSR)- J Frailty Aging (2014) 3 (1) p 39

12 Speaker at the Bowling Green State University Nutrition Symposium Title Sarcopenic obesity Recognizing the hidden enemyrsquo (2013)

13 Speaker at EUUS Task Force on designing drug trials for sarcopenia in frail older adults Title LBM loss in a Bed Rest model Satellite Symposium at International Conference of Frailty and Sarcopenia Research (ICFSR) (2012)

14 Selected oral presentation Effects of HMB on muscle recovery following hind limb suspension in aged rats 5th Cachexia Conference Barcelona Spain (2005)

15 Speaker at the 95th American Oil Chemical Society Meeting Topic Omega-3 fatty acids and cancer cachexia (2004)

16 Selected oral presentation A novel fungal omega-3 desaturase involved in Eicosapentaenoic acid (EPA) production National Plant Lipid Cooperative (NPLC) (2003)

Suzette L Pereira- CV Page 5 of 16

ABBOTT-SPONSORED EXTERNAL PRESENTATIONS 1 Invited speaker at the lsquoCumbre Nacional de Nutrićionrsquo in Colombia (April 5-6 2019) Title

lsquoProtein and HMB The science behind those interesting ingredientsrsquo 2 Invited speaker at the ESPEN 2019 Strength Ambassador Program- Title Nutrition-Focus on

Protein and HMBrsquo 3 Invited speaker at the Turkey KOL meeting at ASPEN 2018 (coordinated by ANI Turkey affiliate)

Topic Loss of Lean Mass- The New Malnutrition 4 Invited speaker at the Strength Ambassador program ESPEN 2018 Topic The Importance of

Muscle and Targeted Nutrition across the Continuum of Care 5 Moderator at ESPEN ANHI-sponsored symposium ESPEN 2018 Topic Nutritional Strategies to

tackle loss of muscle mass and improve patient outcomes across the healthcare continuum 6 Invited speaker at the ANI-Strength Ambassador program held during ESPEN 2017 Topic Loss

of Lean mass The new malnutrition 7 Invited speaker at ANI symposium at Clinical Nutrition Week (Clinical Nutrition Week-ASPEN

2016)- Topic lsquoSpecialized Nutrition The key to maintaining LBM to optimize recoveryrsquo 8 Volwiler Seminar Series Oral presentation (2016) Topic lsquoAddressing Age-Related Muscle Loss

and Weakness Current Approaches and Future Strategiesrsquo 9 Invited speaker to Abbott Nutrition Science Seminar Series (NSSS)- Latin America Sept 26th

2013 Topic Scientific Background of HMBrsquo 10 Effect of HMB on Muscle during Extended Bed Rest in the Elderly (2012) Oral Presentation at

the lsquoMeet the Nutrition Expertrsquo session- ESPEN 2012 (Barcelona Spain)

PATENTS GRANTED 2019

1 EP2672843B1 Nutritional products comprising beta-hydroxy-beta-methylbutyrate 2018

2 US10058113B2 Shelf-stable clear liquid Nutritional compositions comprising Epigallocatechin gallate (EGCg) and methods for preparing the same

3 US9844531 Method of maintaining and improving muscle function 2017

4 US9579347B2 Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss 5 US9675097B2 Shelf Stable clear liquid nutritional composition comprising Epigallocatechin

gallate (EGCg) and methods for preparing the same 6 US9713598B2 Treatment of Insulin Resistance Associated with Prolonged Physical Activity 7 US9844531B2 Method of maintaining and improving muscle function

2014 8 US8916361B2 Elongase gene and uses thereof 9 US8916154B2 Antibodies against delta-5 desaturase and uses thereof 10 EP1507855B2 Elongase genes and uses thereof 11 US8778632B2 Δ6-desaturase genes and uses thereof 12 EP2358869B1 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2013 13 EP2333052B1 Desaturase genes and uses thereof 14 EP2325300B1 Desaturase genes and uses thereof

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 5: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 5 of 16

ABBOTT-SPONSORED EXTERNAL PRESENTATIONS 1 Invited speaker at the lsquoCumbre Nacional de Nutrićionrsquo in Colombia (April 5-6 2019) Title

lsquoProtein and HMB The science behind those interesting ingredientsrsquo 2 Invited speaker at the ESPEN 2019 Strength Ambassador Program- Title Nutrition-Focus on

Protein and HMBrsquo 3 Invited speaker at the Turkey KOL meeting at ASPEN 2018 (coordinated by ANI Turkey affiliate)

Topic Loss of Lean Mass- The New Malnutrition 4 Invited speaker at the Strength Ambassador program ESPEN 2018 Topic The Importance of

Muscle and Targeted Nutrition across the Continuum of Care 5 Moderator at ESPEN ANHI-sponsored symposium ESPEN 2018 Topic Nutritional Strategies to

tackle loss of muscle mass and improve patient outcomes across the healthcare continuum 6 Invited speaker at the ANI-Strength Ambassador program held during ESPEN 2017 Topic Loss

of Lean mass The new malnutrition 7 Invited speaker at ANI symposium at Clinical Nutrition Week (Clinical Nutrition Week-ASPEN

2016)- Topic lsquoSpecialized Nutrition The key to maintaining LBM to optimize recoveryrsquo 8 Volwiler Seminar Series Oral presentation (2016) Topic lsquoAddressing Age-Related Muscle Loss

and Weakness Current Approaches and Future Strategiesrsquo 9 Invited speaker to Abbott Nutrition Science Seminar Series (NSSS)- Latin America Sept 26th

2013 Topic Scientific Background of HMBrsquo 10 Effect of HMB on Muscle during Extended Bed Rest in the Elderly (2012) Oral Presentation at

the lsquoMeet the Nutrition Expertrsquo session- ESPEN 2012 (Barcelona Spain)

PATENTS GRANTED 2019

1 EP2672843B1 Nutritional products comprising beta-hydroxy-beta-methylbutyrate 2018

2 US10058113B2 Shelf-stable clear liquid Nutritional compositions comprising Epigallocatechin gallate (EGCg) and methods for preparing the same

3 US9844531 Method of maintaining and improving muscle function 2017

4 US9579347B2 Methods for enhancing the effect of EGCg on mitigating skeletal muscle loss 5 US9675097B2 Shelf Stable clear liquid nutritional composition comprising Epigallocatechin

gallate (EGCg) and methods for preparing the same 6 US9713598B2 Treatment of Insulin Resistance Associated with Prolonged Physical Activity 7 US9844531B2 Method of maintaining and improving muscle function

2014 8 US8916361B2 Elongase gene and uses thereof 9 US8916154B2 Antibodies against delta-5 desaturase and uses thereof 10 EP1507855B2 Elongase genes and uses thereof 11 US8778632B2 Δ6-desaturase genes and uses thereof 12 EP2358869B1 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2013 13 EP2333052B1 Desaturase genes and uses thereof 14 EP2325300B1 Desaturase genes and uses thereof

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 6: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 6 of 16

2012 15 US8143486B2 Delta-5 Desaturase and Uses Thereof 16 US8143383B2 Delta-6 Desaturase and Uses Thereof 17 US 8188335B2 Delta-9-Elongase for Production of Polyunsaturated Fatty Acid-Enriched Oils 18 US8247653B2 Delta-8 desaturase genes enzymes encoded thereby and uses thereof

2011 19 US7968692B2 Elongase genes and uses there of 20 US8067674B2 Desaturase Genes Enzymes Encoded Thereby and Uses Thereof

2010 21 US7723503 B2 Desaturase genes enzymes encoded thereby and uses thereof

2008 22 US7456270 B2 Δ6-desaturase genes and uses thereof 23 US7375205 B2 Elongase genes and uses thereof 24 US7368552 B2 Genes involved in polyketide synthase pathways and uses thereof

2007 25 US7241619 B2 Desaturase genes and uses thereof 26 US7220897 B2 Δ4-desaturase genes and uses thereof 27 US7211656 B2 Desaturase genes enzymes encoded thereby and uses thereof 28 US7208590 B2 Genes involved in polyketide synthase pathways and uses thereof 29 US7208297 B2 Δ4-desaturase genes and uses thereof 30 US7205134 B2 Δ4-desaturase genes and uses thereof 31 US7211656B2 Desaturase genes enzymes encoded thereby and uses thereof

2006 32 US7067285 B2 Desaturase genes and uses thereof 33 US7045683 B2 Δ4-desaturase genes and uses thereof

2004 34 US6677145 B2 Elongase genes and uses thereof

2003 35 US6635451 B2 Desaturase genes and uses thereof

PATENT APPLICATIONS FILED PENDING 2017

1 Internal Ref 12943USL1 External Ref 4015228-207753 ldquoLiquid Nutritional Compositions Including Green Tea Extract and Ironrdquo Filed August 3 2017

2016 2 12943USL1 Liquid nutritional compositions including green tea extract and iron

2014 3 WO2015095725A1 Methods and compositions for attenuating muscle protein degradation

and preserving lean body mass Filed 121914 4 WO2015094772A1 Methods for increasing skeletal muscle protein synthesis using green tea

extract Filed 121814 5 WO2015094767A1 Methods for maintaining or increasing bodyweight using decaffeinated

green tea extract Filed 121814

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 7: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 7 of 16

6 12441USL1 Methods for increasing muscle strength and mobility in subjects experiencing significant physical inactivity using gamma linolenic acid Filed 091514

7 12363USL1 ldquoMethods of Preserving Muscle Strength During a Period of Muscle Disuse by Administering Beta-Hydroxy-Beta-Methylbutyrate and Green Tea Extractrdquo Filed 091614

8 US 12138USL1 Liquid Nutritional Compositions Comprising GCG and EGCG and Methods for Preparing the Same- Filed 021914

2013 9 Application serial No 61781681- Shelf-stable clear liquid nutritional compositions

comprising EGCg And methods for preparing the same- filed 031413 Abbott Docket 11935USL1

10 Application serial No 61783258 Biomarkers related methods and systems for predicting loss of muscle mass- filed 031413 Abbott Docket 11752USL1

11 Application serial No 61783301- Treatment of insulin resistance associated with prolonged physical inactivity- filed 031413 Abbott Docket 11751USL1

12 Application serial No 61792489 Methods for maintaining and improving muscle function- filed on 031413 Abbott Docket1184USL1

13 Application serial No 61818237 Method for Enhancing Aged Muscle Regeneration Filed on 512013 Abbott Docket 11985USL1

14 Application Serial No 61823832 Methods for Maintaining and Improving Muscle Function Filed on 51513 Abbott Docket 11844USL1 (ID50118)

15 Application serial No 61823550 Nutritional Compositon Comprising Anthocyanadin(s) and Related Methods Filed on 5152013 Abbott Docket 11837USL1

16 Application serial No 61829654 Methods and Compositions for Reducing Angiogenesis and Vascular Hyperpermeability Filed on 5312013 Abbott Docket 11736USL1

17 Application serial No 61829771 Method of Enhancing Muscle Regeneration and Improving Muscle Quality During Aging Muscle Disuse Muscle Overuse Cachexia or Chronic Obstructive Pulmonary Disease Filed on 5312013 Abbott Docket 11982USL1

18 12054USL1 Fibrosis Biomarkers and Methods of Using Same (ID50667) filed Aug 23 2013 19 12053USL1 Methods of Maintaining Intramuscular Myoglobin Levels Maintaining Maximal

Aerobic Capacity and Enhancing the Oxidative Capacity of Muscle in a Subject (ID50665) filed Aug 23 2013

20 Application 11999USL1- Methods of Improving Body Composition and Muscle Function in Sedentary Elderly- Filed 91213

21 Application 11998USL1- Methods of Promoting Muscle Myofiber Growth and Decreasing Muscle Loss in Aged Individuals- Filed 91213

22 11994USL1 Method for Preventing the Loss of Lean Muscle Mass with Age by Administration of a Composition containing Pterostilbene Filed on Sept 9th 2013

23 App 11996USL1- Methods For Maintaining or Increasing Bodyweight Using Decaffeinated Green Tea Extract-filed 12182013 Abbott docket 61917775

24 12028USL1- Methods for Increasing Skeletal Muscle Protein Synthesis Using Green Tea Extract-filed 12182013 Abbott Docket 61917763

25 12068USL1- Compositions and Methods For Increasing 1GF-1 Expression in Skeletal Muscle- Filed 12182013 Abbott Docket 61917792

26 11964USL1- Lean Body Mass Biomarkers And Related Methods Of Using Same- Filed 12192013 Abbott docket 61918483

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 8: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 8 of 16

27 11995USL1- Methods And Compositions For Attenuating Muscle Protein Degradation And Preserving Lean Body Mass- filed 12192013 Abbott docket 61918497

2012 28 11183USL1- Nutritional Compositions Comprising a Polyphenol-Rich Prebiotic and Methods of

Use filed April 2012 29 11376USL1- lsquoMethods for Increasing Muscle Blood Flow and Muscle Energetics Using Beta-

Hydroxy-Beta-Methylbutyrate and Beta-Alanine was filed on 51112 30 11553USL1- Use of szlig-HYDROXY-szlig-METHYLBUTYRATE To Improve Mitochondrial Activity- filed

081012 31 11469USL1- Low Glycemic Index Nutritional Compositions for Preserving Muscle Mass And

Improving Body Composition In Diabetes filed 8142012 32 11661USL1-Nutritional compositions and methods for improving beta-alanine delivery- filed

08212012 33 11608USL1- Shelf-stable clear liquid nutritional compositions comprising EGCg and methods

for preparing the same- filed on 10042012 34 11611USL1ID 50069- Methods for enhancing the effect of EGCg on mitigating skeletal

muscle loss- filed on 100412 35 11604USL1- Administration of BETA-HYDROXY-BETA-METHYLBUTYRATE During Glucocorticoid

Treatment filed on 121112 36 11609USL1- Nutritional Composition Comprising A Cognition Enhancer And Related Methods

filed 122012 37 11749USL1- Use of HMB To Simulate Appetite And Attenuate Body Mass Reduction During

Immobilization And Recovery filed on 12192012 2011

38 10839USL1-lsquoNutritional composition and methods for controlling blood glucosersquo filed on 011311

39 10421USL1- lsquoNutritional composition and methods for improving skeletal muscle protein metabolismrsquo filed on 011311

40 10677USL1- Nutritional products comprising HMB- Filed on 020711 41 10714USL1 Nutritional compositions comprising prune extract and bioavailable curcumin

was filed on March 2 2011 42 11183USL1 Compositions with a polyphenol probiotic

2010 43 US20100273187A1 20100113- Antibodies against Delta-5 desaturase and uses thereof 44 US20100154080 A1 20100617-Delta-8 Desaturase Genes Enzymes Encoded Thereby And

Uses Thereof 2009

45 US20090265798 A1 20091022 Desaturase genes and uses thereof 46 US20090226987 A1 20090910 Desaturase Genes Enzymes Encoded Thereby and Uses

Thereof 47 US20090148919 A1 20090611 Delta 6-Desaturase Genes and Uses Thereof 48 WO2009073822 A3 20091105 The Ohio State University Research FOUNDATION Molecular

Approaches For The Optimization Of Biofuel Production 2008

49 US20080214667 A1 20080904 Elongase Gene and Uses Thereof 50 US20080176944 A1 20080724 Elongase Genes and Uses Thereof

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 9: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 9 of 16

51 US20080125487 A1 20080529 Elongase gene and uses thereof 2007

52 US20070148747 A1 20070628 Genes involved in polyketide synthase pathways and uses thereof

53 US20070124837 A1 20070531 Desaturase Genes Enzymes Encoded Thereby And Uses Thereof

2006 54 US20060048244 A1 20060302 Delta6-desaturase genes and uses thereof

2005 55 US20050014231 A1 20050120 Genes involved in polyketide synthase pathways and uses

thereof 56 US20050009140 A1 20050113 Elongase genes and uses thereof 57 US20050005329 A1 20050106 Delta4-desaturase genes and uses thereof 58 US20050005328 A1 20050106 Delta4-desaturase genes and uses thereof 59 US20050003442 A1 20050106 Delta4-desaturase genes and uses thereof

2003 60 US20030190733 A1 20031009 Desaturase genes and uses thereof 61 US20030196217 A1 20031016 Desaturase genes enzymes encoded thereby and uses

thereof 62 US20030167525 A1 20030904 Desaturase genes and uses thereof 63 US20030157144 A1 20030821 Desaturase genes and uses thereof 64 US20030163845 A1 20030828 Elongase genes and uses thereof 65 US20030134400 A1 20030717 Delta4-desaturase genes and uses thereof

2002 66 US20020138874 A1 20020926 Elongase genes and uses thereof 67 WO2002081668 A3 20031218 Desaturase Genes And Uses Thereof

PUBLICATIONS 1 Rodriacuteguez-Mantildeas L Rodriacuteguez-Saacutenchez B Carnicero JA Rueda R Garciacutea-Garcia FJ Pereira SL

Sulo S (2020) Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults Accepted by Clinical Nutrition httpsdoiorg101016jclnu202007032

2 Langsetmo L Harrison S Jonnalagadda S Pereira SL Shikany J Farsijani S Lane NE Cauley J Stone K Cawthon PM for the Osteoporotic Fractures in Men (MrOS) Research Group (2020) Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men Published J Nutr Health Aging (April 2020)

3 Paul MH Arensberg MB Simon JR Jonnalagadda SS Pereira SL Partridge JS Rosenthal JA (2020) Association between Very Low Dietary Protein Intake and Subsequent Falls in a Community-Dwelling Older Adult Population OBM Geriatrics 2020 4 (2) p 12

4 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Pereira SL (2020) Serum biomarkers that predict lean mass (LM) loss over bed rest in older adults An exploratory study Chemica Clinica ACTA Volume 509 October 2020 Pages 72-78

5 Blasco A Gras S Mogravedol-Caballero G Tarabal O Casanovas A Piedrafita L Barranco A Das T Pereira SL Navarro X Rueda R Esquerda JE Calderoacute J (2020) Motoneuron deafferentation

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 10: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 10 of 16

and gliosis occur in association with neuromuscular regressive changes during aging in mice Accepted Journal of Cachexia Sarcopenia and Muscle

6 Bhasin S et al (the SDOC expert panel including Pereira SL) (2020) The Position Statements of the Sarcopenia Definition and Outcomes Consortium Accepted by Journal of the American Geriatrics Society httpsonlinelibrarywileycomdoiabs101111jgs16372

7 Dvoretskiy S Lieblein-Boff J C Jonnalagadda S Atherton P J Phillips B E amp Pereira S L (2020) Exploring the Association between Vascular Dysfunction and Skeletal Muscle Mass Strength and Function in Healthy Adults A Systematic Review Nutrients 12(3) 715

8 Rodriguez-Mantildeas L and the ISCFR Task Force team including Pereira SL (2019) ICFSR TASK FORCE PERSPECTIVE ON BIOMARKERS FOR SARCOPENIA AND FRAILTY J Frailty Aging 2019 in press Published online October 7 2019 httpdxdoiorg1014283jfa201932

9 Guralnik J and the ISCFR Task Force team including Pereira SL (2019) Clinically meaningful change for physical performance perspectives of the ICFSR task force J Frailty Aging 2019 Published online October 10 2019 httpdxdoiorg1014283jfa201933

10 Cawthon Peggy M et al and the SDOC panel (includes Pereira SL) (2019) Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference The Journals of Gerontology Series A (2019)in press

11 Crossland H Pereira SL Smith K Phillips B E amp Atherton P J (2019) Gene-based analysis of angiogenesis mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation Journal of Functional Foods 56 216-223

12 Goates S Du K Arensberg MB Gaillard T Guralnik J Pereira SL (2019) Economic impact of hospitalizations in US adults with Sarcopenia J Frailty and Aging 8 (2) 93-99

13 Ogura J Sato T Higuchi K Bhutia TD Babu E Masuda M Miyauchi S Rueda R Pereira SL Ganapathy V (2019) Transport mechanisms for the nutritional supplement beta-hydroxy-beta-methylbutyrate (HMB) in mammalian cells Pharmaceutical Research 36(6) 84

14 Alsolmei F A Li H Pereira SL Krishnan P Johns P W amp Siddiqui R A (2019) Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Nutrients 11(5) 1077

15 Pencina KM Bhasin S Luo M Baggs GE Pereira SL Davis GJ Deutz NEP Travison TG (2019) Predictor Biomarkers of Nonelective Hospital Readmission and Mortality in Malnourished Hospitalized Older Adults Accepted J Frailty and Aging - Sept 23 2019

16 Du K Goates S Arensberg MB Pereira SL Gaillard T (2018) Ethnic variations in the prevalence of sarcopenia and sarcopenic obesity with advancing age Diversity and Equality in Health and Care 15(4) 175-183

17 Prado CM Purcell SA Alish C Pereira SL Deutz NE Heyland DK Goodpaster BH Tappenden KA amp Heymsfield SB (2018) Implications of low muscle mass across the continuum of care a narrative review Annals of Medicine Annals of Medicine 1-19

18 Kougias DG Das T Barranco Perez A Pereira SL (2018) A role for nutritional intervention in addressing the aging neuromuscular junction Nutrition Research 53 pp 1-14

19 Sanz-Paris A Camprubi-Robles M Lopez-Pedrosa JM Pereira SL Rueda R Ballesteros-Pomar MD Garcia Almeida JM Cruz-Jentoft AJ (2018) Role of oral nutritional supplements enriched with β-hydroxy-β-methylbutyrate in maintaining muscle function and improving clinical outcomes in various clinical settings J Nutr Health Aging pp1-12

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 11: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 11 of 16

20 Takahashi H Suzuki Y Mohamed JS Gotoh T Pereira SL and Alway SE (2017) Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats Experimental Gerontology 92 pp56-66

21 Standley RA Distefano G Pereira SL Tian M Kelly OJ Coen PM Deutz NE Wolfe RR and Goodpaster BH (2017) Effects of β-hydroxy-β-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics and lipids after 10 days of bed rest in older adults Journal of Applied Physiology ppjap-00192

22 Zhang Z Pereira SL Luo M and Matheson EM (2017) Evaluation of Blood Biomarkers Associated with Risk of Malnutrition in Older Adults A Systematic Review and Meta-Analysis Nutrients 9(8) p829

23 Jeon S Neuringer M Johnson EE Kuchan MJ Pereira SL Johnson EJ and Erdman JW (2017) Effect of carotenoid supplemented formula on carotenoid bioaccumulation in tissues of infant rhesus macaques A pilot study focused on lutein Nutrients 9(1) p51

24 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman Jr JW 2018 Lutein is differentially deposited across brain regions following formula or breast feeding of infant rhesus macaques Journal of Nutrition 148(1) pp31-39

25 Mirza K A Luo M Pereira SL Voss A Das T amp Tisdale M J (2016) In vitro assessment of the combined effect of eicosapentaenoic acid green tea extract and curcumin C3 on protein loss in C2C12 myotubes In Vitro Cellular amp Developmental Biology-Animal 1-8

26 Shreeram S Ramesh S Puthan J K Balakrishnan G Subramanian R Reddy M T amp Pereira SL (2016) Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats Experimental Gerontology 80 6-11

27 Cramer JT Cruz-Jentoft AJ Landi F Hickson M Zamboni M Pereira SL Hustead D Mustad VA (2016) Impact of high-protein oral nutritional supplements among malnourished men and women with sarcopenia A multi-center randomized double-blinded controlled trial JAMDA (17) 1044-1055

28 Meador BM Mirza KA Tian M Skelding MB Reaves LA Edens NK Tisdale MJ Pereira SL (2015) The green tea polyphenol Epigallocatechein-3-gallate (EGCg) attenuates skeletal muscle atrophy in a rat model of sarcopenia J Frailty Aging 4(4) 209-215

29 Kelleher A R Pereira S L Jefferson L S amp Kimball S R (2015) REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1 responses to aging immobilization and remobilization American Journal of Physiology-Endocrinology and Metabolism 308(2) E122-E129

30 Mirza KA Pereira SL Edens NK Tisdale MJ (2014) Attenuation of muscle wasting in murine C2C12 myotubules by epigallocatechin-3-gallate (EGCG) J Cachexia Sacropenia Muscle 5 339-345

31 Garvey SM Dugle JE Kennedy AD McDunn JE Kline W Guo L Guttridge DC Pereira SL Edens NK (2014) Metabolomic Profiling Reveals Severe Skeletal Muscle Group-Specific Perturbations of Metabolism in Aged FBN Rats Biogerontology 15(3) 217-232

32 Mirza KA Pereira SL Voss AC and Tisdale MJ (2014) Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate (HMB) Nutrition 30(7-8) 807- 813

33 Alway SE Bennett BT Edens NK Pereira SL (2014) Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats Exp Gerontol 50 4 82-94

34 Meador BM Pereira SL Edens NK (2013) Green tea and its extracts Current research

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 12: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 12 of 16

literature gaps and product safety J Food Nutr Disor 2013 25 35 Alway SE Pereira SL Edens NK Hao Y Bennett B (2013) β-Hydroxy-β-methylbutyrate

(HMB) increases myogenic stem cell activation in response to reloading following hindlimb suspension in aged rats Exp Gerontol 48 (9) 973ndash984 ndash Top 25 hot papers downloaded in Exp Gerontolog

36 B Vellas Pahor M Manini T Rooks D Guralnik JM Morley J Studenski S Evans W Asbrand C Fariello R Pereira SL Rolland Y Abellan van kan G Cesari M Chumlea WMC Fielding R (2013) Designing pharmaceutical trials for sarcopenia in frail older adults EUUS task force recommendations J Nutr Health Aging 201317(7)612-8

37 Zhang C Iskandarov U Elliott T Klotz ET Stevens RL Cahoon RE Nazarenus TJ Pereira SL and Cahoon EB (2013) A Thraustochytrid Diacylglycerol Acyltransferase 2 with broad substrate specificity strongly increases oleic acid content in engineered Arabidopsis thaliana seeds J Exp Bot 64 (11) 3189-3200

38 Deutz NEP Pereira SL Hays NP Oliver JS Edens NK Evans CM Wolfe RR (2013) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in older adults Clin Nutr 32 (5) 704ndash712

39 Hao Y Jackson JR Wang Y Edens N Pereira SL and Alway SE (2011) -hydroxy- methylbutyrate reduces muscle mass loss and myonuclear apoptosis improving recovery

following hindlimb suspension in aged rats Am J Physiol Regul Integr Comp Physiol Sep 301(3)R701-15

40 Ma H Das T Pereira SL Yang Z Zhao M Mukerji P Hoffman RM (2009) Efficacy Of Dietary Antioxidants Combined With A Chemotherapeutic Agent On Human Colon Cancer Progression In A Fluorescent Orthotopic Mouse Model Anticancer Research 29 2421-2426

41 Sandman K Louvel H Samson RY Pereira SL Reeve JN (2008) Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus Extremophiles 12(6)811-7

42 Johns P Pereira SL Leonard AE Mukerji P Shalwitz RA Dowlati L Phillips RR Bergana MS Holton JD and Das T (2007) Cryoprotective agent in Lactobacillus bulgaricus extracts Current Microbiol 54131-135

43 Huang Y-S Pereira SL and Leonard AE (2004) Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids Biochimie 86 793-798

44 Pereira SL Leonard AE Huang Y-S Chuang L-T and Mukerji P (2004) Identification of two novel microalgal enzymes involved in the conversion of the omega 3-fatty acid Eicosapentaenoic acid (EPA) to Docosahexaenoic acid (DHA) Biochem J 384 357-366

45 Pereira SL Huang Y-S Kinney AJ Packer J Bobik E Stecca K and Mukerji P (2004) A Novel Omega-3 Fatty Acid Desaturase Involved in the Biosynthesis of Eicosapentaenoic Acid Biochem J 378 665-671

46 Leonard AE Pereira SL Sprecher H and Huang Y-S (2004) Elongation of Long-Chain Fatty Acids Prog Lipid Res 43 36-54

47 Pereira SL Leonard AE and Mukerji P (2003) Recent Advances in the Study of Fatty Acid Desaturases from Animals and Lower Eukaryotes Prostaglandins Leukotrienes amp Essential Fatty Acids 68 97-106

48 Sandman K Bailey KA Pereira SL Soares D Li W and Reeve JN (2001) Archaeal Histones and Nucleosomes Methods Enzymol 334 116-129

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 13: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 13 of 16

49 Bailey KA Pereira SL Widom J and Reeve JN (2000) Archaeal Histone Selection of Nucleosome Positioning Sequences and the Prokaryotic origin of Histone-dependent Genome Evolution J Mol Biol 303 25-34

50 Li W Sandman K Pereira SL and Reeve JN (2000) MJ1647 encodes a very thermostable archaeal histone with a C-terminal extension in the hyperthermophile Methanococcus jannaschii Extremophiles 4 43-51

51 Pereira SL and Reeve JN (1999) Archaeal Nucleosome Positioning Sequence from Methanothermus fervidus J Mol Biol 289 675-681

52 Sandman K Pereira SL and Reeve JN (1998) Diversity of Prokaryotic Chromosomal Proteins and the Origin of the Nucleosome Cell Mol Life Sci 54 1350-1364

53 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Archaeal Nucleosomes Proc Natl Acad Sci USA 94 12633-12637

54 Pereira SL and Reeve JN (1997) Histones and Nucleosomes in Archaea and Eukarya A Comparative Analysis Extremophiles 2 141-148

BOOK CHAPTERS

1 Pereira SL and Leonard AE (2006) Omega-3 polyunsaturated fatty acids and cancer cachexia In Dietary fats and the risk of chronic disease Ed Huang Y-S Yanagita T Knapp H AOCS press Champagne IL pp 13-29

2 Huang YS Pereira SL and Leonard AE (2005) Enzyme for the transgenic production of long-chain polyunsaturated fatty acid-enriched oils In Handbook of Biocatalysis (Ching T Hou ed) Chapter 1 Taylor amp Francis Group LLC Boca Raton FL pp I1-I13

PUBLISHED ABSTRACTS

1 Dvoretskiy S Cole T Skelding MB Reaves LA Edens NK and Pereira SL (2020) The green tea catechin EGCg preserves both muscle and bone in aging sarcopenic rats Poster at Experimental Biology 2020

2 Mustad VA Pereira SL Lopez Pedrosa JM Rueda R Gillen ZM Shoemaker ME and Cramer JT (2020) Impaired metabolic flexibility in sarcopenic men and women Poster at ICFSR 2020

3 Jonnalagadda S Harrison SL Rogers-Soeder T Webber K Pereira SL Lane N Cauley J Shikany JM Farsijani S Langsetmo L Cawthon PM (2020) Body weight BMI percent fat lean mass and their long-term associations with mortality and incident mobility limitation Poster at Nutrition 2020

4 Lieblein-Boff J C Dvoretskiy S Pereira SL amp Jonnalagadda S (2019) MON-PO539 Exploring the Association Between Arterial Dysfunction and Skeletal Muscle Mass and Function in Healthy Adults A Systematic Review Clinical Nutrition 38 S258 Presented at ESPEN 2019

5 Jonnalagadda S S Langsetmo L Harrison S L Cauley J Schousboe J T Shikany J M S M Pereira SL amp Cawthon PM (2019) PT02 6 The Association of Protein Intake and Likelihood of Functional Limitations 14 Years Later in Older Men Clinical Nutrition 38 S37-S38 Presented at ESPEN 2019

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 14: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 14 of 16

6 Paul M Arensberg M Partridge J Jonnalagadda S Pereira S amp Simon J (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Journal of the Academy of Nutrition and Dietetics 119(9) A21 Presented at FNCE 2019

7 Rodriacuteguez-Mantildeas L B Rodriguez-Saacutenchez J A Carnicero-Carrentildeo S Sulo D Lanctin J Partridge S Pereira and R Rueda MON-PO542 Malnutrition Prevalence and Burden Among Community-Dwelling Older Spanish Adults Clinical Nutrition 38 (2019) S259

8 Beatriz Rodriguez-Saacutenchez Joseacute Antonio Carnicero-Carrentildeo Suela Sulo Ricardo Rueda Jamie Partridge Suzette Pereira Leocadio Rodriacuteguez-Mantildeas (2019) Role of malnutrition in the development of frailty and cost implications among community-dwellers Oral abstract presented at ICFSR 2019

9 RA Fielding Suzette Pereira T Manini A Newman MM McDermott S Anton SB Kritchevsky R Tracy W Ambrosius J Lopez Pedrosa L Lovato A Santos M Pahor (2019) Effect of omega-3 fatty acid intake on red blood cell fatty acid composition and association with inflammation and mobility Presented at ICFSR 2019

10 Marika Paul Mary Beth Arensberg Jamie Partridge Satya Jonnalagadda Suzette Pereira Judy Simon (2019) Low Dietary Protein Intake Predicts Falls Among Older Adults Presented at the 2019 American College of Preventive Medicine

11 A Blasco S Gras O Tarabal L Piedrafita A Casanovas G Mogravedol X Navarro J Esquerda A Barranco T Das SL Pereira R Rueda and J Calderoacute (2019) Characterization of central and peripheral age-related changes in the neuromuscular system of C57BL6J mice Presented at 12th International Congress on Cachexia Sarcopenia and Muscle Wasting (Berlin)

12 Crossland H Philips B Smith K Pereira SL and Atherton PJ (2018) Gene-Based Analysis of Angiogenesis-Related Pathways in Skeletal Muscle of Older Individuals Following Cocoa Flavanol or Fish Oil Supplementation Poster presented at Nutrition 2018

13 Luo M Pereira SL Baggs GE Nelson JL Deutz NE (2018) Association Between Baseline Levels Of Amino Acids And Their Metabolites And Clinical Outcomes In Malnourished Hospitalized Older Patients Poster presented at ESPEN 2018

14 Goates S Du K Arensberg M E Pereira SL Gaillard T amp Hegazi R (2017) Cost burden of sarcopenia associated hospitalization in adults by age and raceethnicity In VALUE IN HEALTH (Vol 20 No 5 pp A288-A288) 360 PARK AVE SOUTH NEW YORK NY 10010-1710 USA ELSEVIER SCIENCE INC Presented at 2017 ISPOR conference

15 Goates S Du K Arensberg MB Pereira SL Gaillard T Hegazi R (2017) Impact of sarcopenia on falls and hospitalizations in community dwelling older adults Presented at International Conference of Frailty and Sarcopenia Research (ICSFR) - Madrid

16 Zamroziewicz MK Paul EJ Zwilling CE Das T Pereira S and Barbey AK (2017) Prefrontal Cortex Structure Mediates the Relationship between Plasma Phospholipid Stearidonic Acid and Fluid Intelligence in Healthy Older Adults The FASEB Journal 31(1 Supplement) pp460-1

17 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan M Pereira SL Johnson EJ and Erdman JW (2017) A comparison of lutein bioaccumulation in infant rhesus macaques fed breast milk carotenoid-supplemented formula or unsupplemented formula The FASEB Journal 31(1 Supplement) pp32-7

18 Varadharaj S Helal M Duska-McEwen GO Boslett J Pereira SL Buck RH Ahmed N and Zweier JL (2017) The Human Milk Oligosaccharide 3ndashFucosyllactose Facilitates Preservation of Nitric Oxide-Induced Vasodilation in Aortic Vessels In vitro The FASEB Journal 31(1 Supplement) pplb808-lb808

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 15: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 15 of 16

19 Du K Goates S Arensberg MB Pereira S Gaillard T and Hegazi R (2017) Ethnic Variations in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults The FASEB Journal 31(1 Supplement) pplb317-lb317

20 Jeon S Ranard KM Neuringer M Johnson EE Renner L Kuchan MJ Pereira SL Johnson EJ and Erdman JW Jr (2017) Lutein accumulation and xanthophyll binding protein expression in brain and retina of infant rhesus macaques following 6 months of breast milk or infant formulas Presented at the 18th International Symposium on Carotenoids

21 Goates S Du K Pereira S Arensberg ME and Gaillard T (2017) SUN-LB308 The Cost of Sarcopenia Related Hospitalizations in Older Adults Clinical Nutrition 36 pS168

22 Tian M Pereira SL Hustead D Cruz Jentoft A Landi F Zamboni M Mustad M (2016) Characterization of the heterogeneity within a community dwelling sample of malnourished older adults with sarcopenia J Frail Aging (2016) 5 (1) OC32- p36 Oral Presentation-ICSFR Philadelphia 2016

23 Luo M Mirza K A Pereira SL Tisdale M J amp Das T J (2016) Effect of Combination of Low Doses of EPA and Curcumin on Muscle Wasting in MAC16 Colon Tumor-Bearing Mice The FASEB Journal 30 (1 Supplement) lb312-lb312 Poster-Experimental Biology 2016

24 Sathyavageeswaran S and Pereira SL (2016) Age associated decline in the conversion of Leucine to β-Hydroxy-β-Methylbutyrate in rats J Frail Aging 5 (1) OC33- p36 Oral presentation- ICSFR Philadelphia 2016

25 Trevino MB Zhang X Vega RB Coen PM Goodpaster BH Pereira SL Tian M Kelly O and Kelly DP (2016) lsquoExploring Transcriptional Networks Involved in Mitochondrial Energetics That Are Altered With Disuse Atrophyrsquo Poster- U Florida Muscle Biology conference lsquoAdvances in Skeletal Muscle biology in Health and Diseasersquo- January 20-22 2016

26 Zamroziewicz M K Das T Pereira SL amp Barbey A K (2016) Gray Matter Thickness of Inferior Frontal Cortex Mediates the Relationship between Phosphatidylcholine and Executive Functions in Healthy Older Adults The FASEB Journal 30(1 Supplement) 407-7 Poster- EB 2016

27 Matheson EM Luo M Davis GJ Baggs GE Nelson JL Pereira SL Hegaazi RA Ahmed N Steele C Deutz NE and NOURISH Study Group (2016) Effect of a specialized ONS on serum markers of nutrition and inflammation in hospitalized malnourished older patientsrsquo Poster-ESPEN 2016

28 Luo M Mirza K Pereira S Voss A Tisdale M amp Das T (2015) Green Tea Extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster The FASEB Journal 29(1 Supplement) 752-14 Poster-EB 2015

29 Tian M Kline W Edens NK Guttridge DC and Pereira SL (2015) Modulation of Satellite Cell Regenerative Potential by Dietary Plum Extract Poster International Conference of Frailty and Sarcopenia Research (ICFSR)-Boston April 2015

30 Luo M Mirza KA Pereira SL Voss AC Tisdale MJ Das T (2015) Green tea extract and Curcumin Enhanced the Benefit of EPA on Muscle Wasting Poster Experimental Biology- Boston 2015

31 Tian M and Pereira SL (2014) Comparison of Two Clinical Models of Immobilization on Lean Body Mass Outcomes in Healthy Adults Bed Rest vs Leg Casting Poster ICFSR-Barcelona Spain March 2014 J Frailty Aging 3 (1) p 71 (P175)

32 Davis GJ Gawel SH Luo M Deutz NE Wolfe RR Edens NK Pereira SL (2014) Serum biomarkers that predict clinical outcomes in an immobilized population Predictors of lean body mass loss Presented at the American Association for Clinical Chemistry - July 31 2014

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)

Page 16: SUZETTE L. PEREIRA, Ph.D....Suzette L. Pereira- CV Page 1 of 16 SUZETTE L. PEREIRA, Ph.D. SENIOR ASSOCIATE VOLWILER RESEARCH FELLOW Abbott Nutrition, Strategic R&D 3300 Stelzer Road,

Suzette L Pereira- CV Page 16 of 16

33 Pereira SL Luo M Davis GJ Gawel SH Chandran R Deutz NE Wolfe RR Edens NK (2013) -

hydroxy--methlybutyrate (HMB) modulates circulating biomarkers in older adults on extended bedrest (BR) Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S226

34 Gawel SH Luo M Davis GJ Deutz NEP Wolfe RR Edens NE Pereira SL (2013) Serum biomarkers that predict lean body mass (LBM) loss over bedrest (BR) in older adults Poster ESPEN 2013 Leipzig Germany Clin Nutr(2013) 32(1) S228

35 Sathya S Pereira SL Gelling R Edens N (2013) Beta-hydroxy-betamethyl butyrate attenuates dexamethasone-induced muscle atrophy in rats Oral Asia Pacific Conference on Clinical Nutrition APCCN (Tokyo Japan June 2013)

36 Garvey SM Guo L Kennedy AD McDunn JE Pereira SL (2013) Metabolomic profiling of aging rat skeletal muscle Poster Experimental Biology (Boston MA April 2013)

37 Deutz NE Hays NP Pereira SL Oliver JS Edens NK Evans CM Wolfe RR (2011) Lean body mass is maintained by β-hydroxy-β-methylbutyrate (HMB) during 10 days of bed rest in elderly women Poster ESPEN Gothenburg Sweden September 2011

38 Krishnan P Pereira SL Das T DeMichele S and Edens NK (2010) Lipid-antioxidant blend for modulating chronic inflammation in Type 2 Diabetes Poster Obesity Conference October 2010

39 Hao Y Jackson JR Scheller E Wang Y Pereira SL and Alway SE (2010) Effects of beta-hydroxy-beta-methylbutyrate on markers of muscle hypertrophy and apoptotic signaling during reloading in aged rats following disuse PosterOral presentation American College of Sports Medicine April 2010

40 Kline W Pereira SL and Guttridge D (2009) Evaluation of an aged animal model of sarcopenia Poster Muscle Biology and Disease Symposium Ohio State University April 2009

41 Pereira SL Grayling RA Lurz R and Reeve JN (1997) Identification of the in vivo DNA-binding sites of the archaeal histone HMf in the hyperthermophilic methanogen Methanothermus fervidus Poster American Society for Microbiology (ASM) General Meeting May 1997

42 Pereira SL Grayling RA Sandman K and Reeve JN (1996) Isolation and characterization of the archaeal histone HMt-DNA complexes formed in vivo in Methanobacterium thermoautotrophicum Poster American Society for Microbiology (ASM) General Meeting May 1996

43 Pereira SL Bailey K and Reeve JN (1996) The study of histone-DNA complexes in thermophilic methanogens Poster Ohio-Indiana Branch Meeting of the American Society for Microbiology April 1996

44 Grayling RA Sandman K Pereira SL and Reeve JN (1995) The HMf proteins from Methanothermus fervidus are thermostable prokaryotic histones with a structural-specific

DNA-binding preference Poster American Society for Microbiology (ASM) General Meeting May 1995

MEMBERSHIPS New York Academy of Sciences

American Society for Nutrition American Oil Chemical Society (AOCS) Abbott- Women Leaders in Action (WLA)