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Surgical Options for Weight Regain after Gastric Bypass Alfonso Torquati, MD, MSCI, FACS Associate Professor and Chief Division of Metabolic and Bariatric Surgery

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Page 1: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Surgical Options for Weight Regain after Gastric Bypass

Alfonso Torquati, MD, MSCI, FACS

Associate Professor and Chief

Division of Metabolic and Bariatric Surgery

Page 2: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Disclosures

Allergan: grant support

Covidien: consulting agreement

2

Page 3: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Definition of a RYGB “Failure”

Inadequate initial EWL: <50%

Significant Weight Regain :> 20% of weight gain

above nadir weight

Page 4: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5

and 10 years postoperatively

Wide consensus that weight regain (20% of

weight gain above nadir weight)warrants

surgical anatomy evaluation : • EGD

• Upper GI contrast study

4

Page 5: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Surgical Causes of Weight Regain after RYGB

Large pouch at time of

surgery

Dilated gastric pouch

5

Page 6: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Surgical Causes of Weight Regain after RYGB

Gastro-gastric fistula

Dilated gastro-jejunostomy

6

Page 7: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Other Causes of Weight Regain after RYGB

hyperphagia

polyphagia

sweet eating

Lack of exercise

Steroids

Pregancy

Page 8: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Multidisciplinary consultation - radiologist

- gastroenterologist

- nutritionist

- psychologist

Page 9: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

MAIN CAUSES OF RYGB FAILURES

Treatment: LAPAROSCOPIC or ENDOSCOPIC

TECHNICAL PROBLEMS

1- gastric pouch dilatation

2- gastrojejunostomy dilatation

3- presence of gastro-gastric fistula

Page 10: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

MAIN CAUSES OF RYGB FAILURES

1) Gastric pouch dilatation:

- Laparoscopic resection or plication

- Endoscopic plication

2) Gastrojejunostomy dilatation:

- Endoscopic plication or sclerosing agent

3) Presence of gastro-gastric fistula

- Laparoscopic resection

- Endoscopic closure

Page 11: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

G-G Fistula Laparoscopic Technique

1- lateral to medial approach

2- isolation greater curve of gastric remnant (body to

fundus)

3- section of remnant from gastric pouch (fundectomy)

4- try to salvage the gastrojejunostomy

Page 12: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Dealing with Polyphagia

polyphagia = grazing, eating too frequent

meals

conversion to malabsorptive procedure:

DISTAL RYGB

Kellum JM, et al. SOARD 2011;7:189-93

Rawlins ML et al. SOARD 2011;7:45-9

Brolin RE et al. J Gastrointest Surg 2002;6:195-205

Fobi MAL et al. Obes Surg 2001;11:190-5

Surgerman HJ et al. J Gastrointest Surg 1997;6:517-25

Page 13: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Confusion?

Page 14: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Nelson WK, Fatima J, Houghton SG, Thompson GB,

Kendrick ML, Mai JL, Kennel KA, Sarr MG. The

malabsorptive very, very long limb Roux-en-Y gastric

bypass for super obesity: Results in 257 patients

Surgery Volume 140, Issue 4 2006 517 - 523

Terminology

Page 15: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Giovanni Dapri, Guy Bernard Cadière, and Jacques Himpens. Journal of Laparoendoscopic & Advanced Surgical

Techniques. January/February 2011, 21(1): 19-23.

Revision to distal RYGB

Page 16: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Comparison of weight, BMI, and % excess weight loss (%EWL) at RYGB, at extreme values before the conversion to

DRYGB, at the conversion, and at follow-up (mean values).

Giovanni Dapri, Guy Bernard Cadière, and Jacques Himpens. Journal of Laparoendoscopic & Advanced Surgical

Techniques. January/February 2011, 21(1): 19-23.

Between April 2005 and November 2009, 7 patients benefited from laparoscopic conversion of

RYGB to DRYGB for weight regain mainly due polyphagia

Revision to distal RYGB

Page 17: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Revision to Distal RYGB

Page 18: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Proximal vs. Distal RYGB

Page 19: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Characteristics of the two groups

Page 20: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Results

British Journal of Surgery

Volume 95, Issue 11, pages 1375-1379, 9 OCT 2008

Page 21: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Sweet Eating: Conversion to DS

Page 22: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

RYGB to DS Taking down Roux Limb

Gastro-Gastrostomy

Sleeve Gastrectomy

Duodenoileostomy

Ileoileostomy

Jejunojejunostomy

Page 23: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Dealing with Hyperphagia

hyperphagia = volume eating, eating too large

meals

Increased restriction by placement of band

(adjustable or non)

Irani K et al. SOARD 2011;7:219-24

Bessler M et al. SOARD 2010;6:31-5

Chin PL et al. SOARD 2009;5:38-42

Gobble RM et al. Surg Endosc 2008;22:1019-22

Page 24: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus
Page 25: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Excess body mass index loss (%EBMIL)

after revision. Values shown for follow-up

(in months) after revisional surgery (t = 0).

Page 26: Surgical Options for Weight Regain after Gastric Bypass · Weight Regain after RYGB Estimated 10 - 30% of patients will regain weight at 5 and 10 years postoperatively Wide consensus

Conversion of RYGB into Distal RYGB