sulis bayu sentono, m.d. †, young choi, m.d., chin youb chung, m.d., soon-sun kwon, ph.d.*, kyoung...

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Sulis Bayu Sentono, M.D. , Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. Department of Orthopaedic Surgery, Airlangga University Dr Soetomo Hospital, East Java, Indonesia. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Kyungki, Korea. * Biomedical Research Institute, Seoul National University Bundang Hospital, Kyungki, Korea

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Page 1: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Sulis Bayu Sentono, M.D.†, Young Choi, M.D., Chin Youb Chung, M.D.,Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D.

†Department of Orthopaedic Surgery, Airlangga University Dr Soetomo Hospital, East Java, Indonesia. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Kyungki, Korea. *Biomedical Research Institute,

Seoul National University Bundang Hospital, Kyungki, Korea

Page 2: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

To assess progression of hip subluxation after femoral varization derotation osteotomy (FVDO) in patients with cerebral palsy using a Linear Mixed Model (LMM) application and determined factors influence it

Page 3: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Hip subluxation and dislocation in children with

spasticity resulting from CP may cause serious problems

for affected patient

Satisfactory short term results after FVDO or combined

with Dega pelvic osteotomy for the treatment of hip

subluxation and dislocation were reported by many

authors

There are only a few long term studies reporting

recurrency after FVDO or combined with Dega pelvic

osteotomy after some periodic follow-up.

Page 4: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

This study was a retrospective design

Patients with CP, who visited our hospital and underwent FVDO or combined with Dega pelvic osteotomy between from 2003 Jun. to 2012 Oct.

Investigate using X-ray in AP and Internal rotation view to assess Neck shaft angle(NSA), Head shaft angle (HAS), Migration percentage(MP) on pre-operative, immediate post operative and until last follow up

Page 5: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

For each of GMFCS level, the value of measurements (NSA, HSA, MP) was adjusted by multiple factors by using a Linear Mixed Model (LMM) with gender as the fixed effects and follow-up time (years) effect, laterality (side of hip) and each subject as the random effect

Page 6: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of
Page 7: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of
Page 8: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Figure 1.:The angle between a line passing through the midway of the femoral shaft and another line connecting the femoral head center and midpoint of the femoral neck. The femoral head center was the center of best fitting outer circle of the femoral head.

Pre Operative

Post Operative

Page 9: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Figure 1.:The head shaft angle was the angle between line passing through the femoral shaft midway and another line perpendicular to the proximal femoral physis.

Pre Operative

Post Operative

Page 10: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Figure 1.:The migration percentage was calculated by dividing the amount of the femoral head lateral to the Perkin’s line (A) with the total width of the femoral head (B)

Pre Operative

Post Operative

Page 11: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

There were one hundreds and fourty-four hips in 76 bilateral spastic CP patients

All were bilateral CP type with GMFCS II-III / IV / V were 12 / 30 / 34, respectively

All got bilateral FVDO in equal amount and 80 hips combined with Dega pelvic osteotomy

There were 57 males and 19 females with an average age at surgery was 8.5 ± 2.3 years (SD range from 4.5 to 16.5 years) and duration of follow up was 4.9±2.4 years

Page 12: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Parameters Values

Patient’s Information

No. of patients (M/F) 76(57/19)

CP type (Uni/Bi) 0/76

GMFCS (II-III/IV/V) 12/30/34

Age at surgery (yr) 8.5 ± 2.3

Follow up duration 4.9±2.4

Type of surgery

No. of Hips involved (Right/Left)

144(72/72)

FVDO (Right/Left) 144(72/72)

Dega PO (Right/Left) 80(45/35)

Page 13: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Parameters Values

Radiographic characteristics

NSA (°)

Preop 151.3±9.9

Immediate postop 129.0±14.6

Last F/U 129.1±15.3

HSA (°)

Preop 161.1±9.0

Immediate postop 141.9±13.9

Last F/U 142.9±14.7

MP (%)

Preop 53.7±30.0

Immediate postop 11.9±13.9

Last F/U 16.3±14.2

Page 14: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

Estimate(%)

95% CI p

GMFCS II-III

(Intercept) 12.4 -0.8 to 25.5 0.062

Gender Male 11.4 -2.5 to 25.3 0.106

Side of hip Right -2.8 -8.3 to 2.7 0.285

Follow up Year 0.7 -4.1 to 5.5 0.742

GMFCS IV

(Intercept) 18.7 10.5 to 26.9 <0.001

Gender Male -7.1 -15.6 to 1.4 0.100

Side of hip Right -0.8 -5.1 to 3.5 0.694

Follow up Year 1.9 1.0 to 2.8 <0.001

GMFCS V

(Intercept) 11.2 0.2 to 22.1 0.046

Gender Male -1.7 -13.2 to 9.8 0.774

Side of hip Right -0.8 -6.2 to 4.7 0.777

Follow up Year 3.5 1.3 to 5.8 0.003

Page 15: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of
Page 16: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of
Page 17: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of
Page 18: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

There is progression of hip subluxation after FVDO in patients with CP particularly in patients non-ambulatory (GMFCS level IV and V)

Time of follow-up duration has main role in the occurency of this postulated

Page 19: Sulis Bayu Sentono, M.D. †, Young Choi, M.D., Chin Youb Chung, M.D., Soon-Sun Kwon, Ph.D.*, Kyoung Min Lee, M.D., Moon Seok Park, M.D. † Department of

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2. Lee KM, et all.Clinical Relevance of Valgus Deformity of Proximal Femur in Cerebral Palsy.J Pediatr Orthop 2010;10:720-725

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4. Noonan KJ, Walker TL, Kayes KJ, Feinberg J. Varus derotation osteotomy for the treatment of hip subluxation and dislocation in cerebral palsy: Statistical analysis in 73 hips. J Pediatr Orthop B 2001; 10: 279-286

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6. Noonan KJ, Walker TL, Kayes KJ, Feinberg J.Effect of surgery on the nontreated hip in severe cerebral palsy. J Pediatr Orthop 2000;20:771-775

7. Samilson RL, et al. Dislocation and subluxation of the hip in cerebral palsy. The Journal of Bone and Joint Surgery 1972;54-A :863-873

8. Howard CB, McKibbin B, Williams LA, Mackie I. Factors affecting the incidence of hip dislocation in cerebral palsy. The Journal of Bone and Joint Surgery 1985; 67-B: 530-532

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14. Canavese F, Emara K, Sembrano JN, Bialik V, Aiona MD, Sussman MD. Varus Derotation Osteotomy for the Treatment of Hip Subluxation and Dislocation in GMFCS Level III to V Patients With Unilateral Hip Involvement. Follow-up at Skeletal Maturity. J Pediatr Orthop. 2010;30:357–364)