S DNG NCBI TRONG CNG NGH SINH HC

GVHD: PGS.TS Chu Hong Mu Hc vin thc hin: Mn: tip cn cng ngh sinh hc

1. C s d liu NCBI:

NCBI : c s d liu Trung tm quc gia v cng ngh sinh hc M ( National Centre Biotechnology Infomatic ), thnh lp nm 1988 t mt phn ca th vin y hc NIH ( National Institutes of Health ). NCBI l c s d liu sinh hc ln nht th gii, Cung cp cc thng tin v trnh t Nuclotide, cu trc chui amino acid, cu trc gen cc loi,cc thng tin trong NCBI c t chc qun l theo tng nhm tin v gia chng c s kt ni cht ch.

cho php cung cp cc d liu v trnh t gen, n cng l cng c gip khai thc, phn tch d liu v nucleotide v cung cp min ph cc thng tin cn thit. Trang web ca NCBI l: www.ncbi.nlm.nih.gov Vo google: www.ncbi.nlm.nih.gov search. NCBI

2. Gii thiu v trang web NCBI:

2.1 cc dch v ca NCBI 2.1.1.Pubmed:

cho php khai thc cc cng trnh cng b trong MEDLINE v cc cng trnh c lin quan c cng ch . 2.1.2. BLAST ( basic Local Alignment Search Tools ): so snh trnh t gen. 2.1.3. VAST ( Vector Alignment Search Tools ): nghin cu cu trc tng ng.

2.1.1.1 cch tm kim bi bo khoa hc.

Xc nh cc t then cht trong tm kim Nhp t vo hp tm kim Nhp search tin hnh tm kim Pubmed.

Cch tm kim tn tc gi

Cch tm kim tn tp ch

Nucleotide

nucleotid

nucleotid

nucleotid

genome

genome

protein

protein

Gene

Gene