RIBONUCLEIC ACID (RNA)

V.S.RAVIKIRAN, MSc.

V.S.RAVIKIRAN, MSc., Department of Biochemistry,

ASRAM Medical college, Eluru-534005.AP, India.vsravikiran2013@gmail.c

om

RIBONUCLEIC ACIDSV.S.RAVIKIRAN

RNA

Ribonucleic Acid

Structure of RNA

• Single stranded• Ribose Sugar• 5 carbon sugar• Phosphate group• Adenine, Uracil, Cytosine, Guanine

Types of RNA

• Three main types• Messenger RNA (mRNA) – transfers DNA code

to ribosomes for translation.• Transfer RNA (tRNA) – brings amino acids to

ribosomes for protein synthesis.• Ribosomal RNA (rRNA) – Ribosomes are made

of rRNA and protein.

Structure of RNA

1. Ribosome RNA (rRNA), 80%

2. Transfer RNA (tRNA), 15%

3. Messenger RNA (mRNA), 5%

•Carry genetic information from DNA to cytosol •Template for protein synthesis

Structure of mRNA1. Ribosome RNA (rRNA), 80%

2. Transfer RNA (tRNA), 15%

3. Messenger RNA (mRNA), 5%

•Carry genetic information from DNA to cytosol •Template for protein synthesis

Structure of mRNA1. Ribosome RNA (rRNA), 80%

2. Transfer RNA (tRNA), 15%

3. Messenger RNA (mRNA), 5%

•Carry genetic information from DNA to cytosol •Template for protein synthesis

Structure of tRNA1. Ribosome RNA (rRNA), 80%

2. Transfer RNA (tRNA), 15%

• At least one specific type of tRNA for each of the 20 amino acids • Carry its specific amino acid to the site of protein synthesis

Structure of RNA1. Ribosome RNA (rRNA), 80%

2. Transfer RNA (tRNA), 15%

RNA is very flexible, and forms complex structures, like these in a tRNA molecule:

tRNA ( transfer RNA)is a small RNA that has a very specific secondary and tertiary structure such that it can bind an amino acid at one end, and mRNA at the other end. It acts as an adaptor to carry the amino acid elements of a protein to the appropriate place as coded for by the mRNA. T

Secondary structure of tRNA

Three-dimensional Tertiary structure

Structure of rRNA1. Ribosome RNA (rRNA), 80%

• Components of ribosome• Facilitate the binding and positioning of the mRNA on the ribosomes

THE END

THANKS FOR YOUR ATTENTION