stored blood

1
768 STORED BLOOD late war to establish the technique of oxygen administration for flying at high altitudes, and he also showed the value of oxygen for long flights at lower heights (10,000-12,000 ft.) as a means of lessening fatigue. Group-Captain G. S. Marshall, who succeeded Flack as physiologist, working with the Air Ministry’s scientific research staff at Farn- borough, has developed the present method of supplying oxygen at high altitudes, using pressure suits at heights above 35,000 ft. ; it was in one of these suits that the late Flight-Lieutenant M. J. Adams attained a height of 54,000 ft.-a record only recently broken by the Italian, Colonel Pezzi, when he reached 56,000 ft. last October. Nervous factors concerned with flying and the mental attitude for aviation were studied from 1917 to 1920 by Henry Head, W. H. R. Rivers and Squadron-Leader P. S. R.ippon, and as a result certain tests for nervous stability and additional questions of family and personal history have been incorporated in the medical examination of candi- dates for flying. Group-Captain H. L. Burton, the consultant in neurology, has continued this work, especially in connexion with prognosis where there are significant temperamental defects and excellencies, and Squadron-Leader G. 0. Williams, working with Prof. Bartlett, has apparently succeeded in foretelling the flying aptitude of candidates by means of sensorimotor coordinating machines and a form-relation test, which may revolutionise medical examinations. The medical entrance examination for the R.A.F. has been continually under review, and certain modifications have been made from time to time. Group-Captain H. A. Treadgold, when consultant in medicine, introduced the orthodiagram and electrocardiogram into the examination ; he also established a relationship between body-build and functional efficiency and studied the significance of blood-pressure. This work has been pursued by his successor, Group-Captain A. F. Rook, who, in conjunction with Flight-Lieutenant Dawson, published an article on hypotension and flying in this journal last December. Wing-Commander E. D. D. Dickson, consultant in otolaryngology, has demonstrated the loss of auditory acuity resulting from continued exposure to present-day aeroplane noise, and with Mr. A. W. G. Ewing, Ph.D., and Mr. T. S. Littler, Ph.D., of Manchester, has been investigating ways of protecting the ears of aircraft crews against excessive stimulation. In ophthalmology, too, considerable progress has been made-first, by Group-Captain E. C. Clements, who instituted a training for heterophoria, to help prevent bad landings due to this condition, and who cooperated with the Air Ministry scientific staff in improving bomb-sight and cockpit lighting ; and since 1934 by Wing-Commander P. C. Livingston, the present consultant in ophthalmology, who has perfected the heterophoria training and has been mainly responsible for the development of new flying goggles and spectacles which counteract the effects of glare from the sun and from night- landing flares. ANNOTATIONS STORED BLOOD EXPERIENCE of stored blood for transfusion has been limited in this country to small groups of patients. In our present issue Dr. F. Duran Jorda, who was head of the blood-transfusion service of the Spanish republican army, describes his conclusions drawn from experience with 9000 litres of blood obtained from 20,000 withdrawals and the classifica- tion of 28,900 donors. His methods of withdrawal and storage appear complicated on paper, but medical visitors to his institute in Barcelona and those who have had the privilege of talking to him in London are impressed by the simplicity of the method in action. It is clearly a great advance on any system that has been advocated in this country. The great advantage, especially in time of war, is that large quantities of blood (25-30 litres per hour) can be withdrawn and prepared for use in a short time under sterile conditions. The apparatus is so devised that administration of the blood is very simple and can be carried out single-handed by anyone capable of doing a venepuncture. The greatest danger with stored blood is haemolysis, which lessens the thera- peutic value of the blood and favours reactions after transfusion. The commonest cause of haemolysis is shaking the blood in transit. Duran Jorda has reduced movement of the blood to a minimum by his special ampoule. This fact alone should attract close attention to his technique. In time of war blood may have to be transported for long distances, and any system that prevents it from being shaken is clearly important. The blood is stored under two atmospheres’ pressure of air ; this facilitates adminis- tration and, Duran Jorda believes, establishes an automatic bacteriological control. The oxygen present prevents the growth of anaerobes, while if aerobes are present they grow at the expense of the oxygen, thus converting the bright red oxyhaemoglobin into dark red reduced hsemoglobin. A glance at the flask, he claims, is sufficient to show whether the blood is sterile. He advocates the use only of group IV-0 blood for emergency purposes, for it is impossible to obtain accurate grouping under war-time conditions. He mixes the blood from different donors, because in this way the agglutinin titre is reduced and a more homogeneous blood obtained. Some patients received transfusions from as many as 96 donors without ill effects. The work he describes is of biological interest as well as of practical importance in both peace and war. PSYCHIATRIC ASPECTS OF CRIME THE official inquiry by Norwood East and Hubert 1 into the treatment of crime produced much that is of technical interest to psychiatrists in addition to the administrative proposals which are its chief practical outcome and which were commented on in our issue of March 11 (p. 583). During the last four years Dr. Hubert has investigated more than 400 selected offenders and his conclusions as to the form, psychopathology, and therapeutic possibilities of their disorders are a valuable contribution to forensic psychiatry. A preliminary objection likely to be made is that his material might have been unduly 1. The Psychological Treatment of Crime. By W. Norwood East and W. H. de B. Hubert. 1939. H.M. Stationery Office.

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768 STORED BLOOD

late war to establish the technique of oxygenadministration for flying at high altitudes, andhe also showed the value of oxygen for long flightsat lower heights (10,000-12,000 ft.) as a means oflessening fatigue. Group-Captain G. S. Marshall,who succeeded Flack as physiologist, working withthe Air Ministry’s scientific research staff at Farn-borough, has developed the present method of

supplying oxygen at high altitudes, using pressuresuits at heights above 35,000 ft. ; it was in one ofthese suits that the late Flight-Lieutenant M. J.Adams attained a height of 54,000 ft.-a recordonly recently broken by the Italian, Colonel Pezzi,when he reached 56,000 ft. last October. Nervousfactors concerned with flying and the mentalattitude for aviation were studied from 1917 to1920 by Henry Head, W. H. R. Rivers and

Squadron-Leader P. S. R.ippon, and as a resultcertain tests for nervous stability and additionalquestions of family and personal history have beenincorporated in the medical examination of candi-dates for flying. Group-Captain H. L. Burton,the consultant in neurology, has continued thiswork, especially in connexion with prognosiswhere there are significant temperamental defectsand excellencies, and Squadron-Leader G. 0.Williams, working with Prof. Bartlett, has

apparently succeeded in foretelling the flyingaptitude of candidates by means of sensorimotorcoordinating machines and a form-relation test,which may revolutionise medical examinations.The medical entrance examination for the R.A.F.

has been continually under review, and certainmodifications have been made from time to time.

Group-Captain H. A. Treadgold, when consultantin medicine, introduced the orthodiagram and

electrocardiogram into the examination ; he alsoestablished a relationship between body-build andfunctional efficiency and studied the significanceof blood-pressure. This work has been pursuedby his successor, Group-Captain A. F. Rook, who,in conjunction with Flight-Lieutenant Dawson,published an article on hypotension and flying inthis journal last December. Wing-CommanderE. D. D. Dickson, consultant in otolaryngology,has demonstrated the loss of auditory acuityresulting from continued exposure to present-dayaeroplane noise, and with Mr. A. W. G. Ewing,Ph.D., and Mr. T. S. Littler, Ph.D., of Manchester,has been investigating ways of protecting the earsof aircraft crews against excessive stimulation. In

ophthalmology, too, considerable progress has beenmade-first, by Group-Captain E. C. Clements,who instituted a training for heterophoria, to helpprevent bad landings due to this condition, andwho cooperated with the Air Ministry scientificstaff in improving bomb-sight and cockpit lighting ;and since 1934 by Wing-Commander P. C. Livingston,the present consultant in ophthalmology, who hasperfected the heterophoria training and has beenmainly responsible for the development of new

flying goggles and spectacles which counteract theeffects of glare from the sun and from night-landing flares.

ANNOTATIONS

STORED BLOOD

EXPERIENCE of stored blood for transfusion hasbeen limited in this country to small groups of

patients. In our present issue Dr. F. Duran Jorda,who was head of the blood-transfusion service of the

Spanish republican army, describes his conclusionsdrawn from experience with 9000 litres of bloodobtained from 20,000 withdrawals and the classifica-tion of 28,900 donors. His methods of withdrawaland storage appear complicated on paper, but medicalvisitors to his institute in Barcelona and those whohave had the privilege of talking to him in Londonare impressed by the simplicity of the method inaction. It is clearly a great advance on any systemthat has been advocated in this country. The greatadvantage, especially in time of war, is that largequantities of blood (25-30 litres per hour) can bewithdrawn and prepared for use in a short time understerile conditions. The apparatus is so devised thatadministration of the blood is very simple and canbe carried out single-handed by anyone capable ofdoing a venepuncture. The greatest danger withstored blood is haemolysis, which lessens the thera-peutic value of the blood and favours reactions aftertransfusion. The commonest cause of haemolysis is

shaking the blood in transit. Duran Jorda hasreduced movement of the blood to a minimum by hisspecial ampoule. This fact alone should attract closeattention to his technique. In time of war blood

may have to be transported for long distances, andany system that prevents it from being shaken is

clearly important. The blood is stored under two

atmospheres’ pressure of air ; this facilitates adminis-

tration and, Duran Jorda believes, establishes anautomatic bacteriological control. The oxygen presentprevents the growth of anaerobes, while if aerobes arepresent they grow at the expense of the oxygen, thusconverting the bright red oxyhaemoglobin into darkred reduced hsemoglobin. A glance at the flask, heclaims, is sufficient to show whether the blood issterile. He advocates the use only of group IV-0blood for emergency purposes, for it is impossible toobtain accurate grouping under war-time conditions.He mixes the blood from different donors, because inthis way the agglutinin titre is reduced and a morehomogeneous blood obtained. Some patients receivedtransfusions from as many as 96 donors withoutill effects. The work he describes is of biologicalinterest as well as of practical importance in bothpeace and war.

PSYCHIATRIC ASPECTS OF CRIME

THE official inquiry by Norwood East and Hubert 1into the treatment of crime produced much thatis of technical interest to psychiatrists in additionto the administrative proposals which are its chiefpractical outcome and which were commented onin our issue of March 11 (p. 583). During the lastfour years Dr. Hubert has investigated more than400 selected offenders and his conclusions as to theform, psychopathology, and therapeutic possibilitiesof their disorders are a valuable contribution toforensic psychiatry. A preliminary objection likelyto be made is that his material might have been unduly1. The Psychological Treatment of Crime. By W. Norwood

East and W. H. de B. Hubert. 1939. H.M. StationeryOffice.