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Hemodialysis angioaccesses State of the art & future trends: AN ITALIAN’S PERSPECTIVE Nicola Pirozzi Department of Clinical and Molecular Medicine “Sapienza” University of Rome

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Page 1: State of the art & future trends: AN ITALIAN’S PERSPECTIVEcacvsarchives.org/archivesite/2014/pdf/presentations/Pre0034-PIROZZI... · A V F . Prevalent patients - type of vascular

Hemodialysis angioaccesses

State of the art & future trends:

AN ITALIAN’S PERSPECTIVE

Nicola Pirozzi

Department of Clinical and Molecular Medicine “Sapienza” University of Rome

Page 2: State of the art & future trends: AN ITALIAN’S PERSPECTIVEcacvsarchives.org/archivesite/2014/pdf/presentations/Pre0034-PIROZZI... · A V F . Prevalent patients - type of vascular

Disclosure

Speaker name: Nicola Pirozzi

.................................................................................

I have the following potential conflicts of interest to report:

Consulting (BARD)

Employment in industry

Shareholder in a healthcare company

Owner of a healthcare company

Other(s)

I do not have any potential conflict of interest

X

Page 3: State of the art & future trends: AN ITALIAN’S PERSPECTIVEcacvsarchives.org/archivesite/2014/pdf/presentations/Pre0034-PIROZZI... · A V F . Prevalent patients - type of vascular

- ITALIAN REGISTRY

- epidemiology

- treatments

- outcomes

- “NEFROLOGIA INTERVENTISTICA”

- PERSONAL EXPERIENCE

TOPICS

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ITALIAN REGISTRY

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Incidence : 160 pmp

Prevalence : 800 pmp

Incident >72y: 50%

Prevalent > 74y: 36%

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HTA DM VASCULOPATY

CO-MORBIDITY

FUTURE CHALLENGES

• PATENCY OF

ARTERIES AND VEINS

• HAIDI

• HIGH FLOW

Page 7: State of the art & future trends: AN ITALIAN’S PERSPECTIVEcacvsarchives.org/archivesite/2014/pdf/presentations/Pre0034-PIROZZI... · A V F . Prevalent patients - type of vascular

Incident patients - type of vascular access

Central venous catheter 48.5% (in 2002: 23%)

Arterio-venous fistula 51.5% (in 2002: 76%)

AV graft <1%

C

V

C

A

V

F

Page 8: State of the art & future trends: AN ITALIAN’S PERSPECTIVEcacvsarchives.org/archivesite/2014/pdf/presentations/Pre0034-PIROZZI... · A V F . Prevalent patients - type of vascular

Prevalent patients - type of vascular access

CVC 19.7% (in 2002: 6%)

AVF 78.5% (in 2002 : 92%)

AV graft <3% (in 2002 <3%)

C

V

C

A

V

F

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AUTOLOGOUS ARTERIO-VENOUS FISTULA (AVF)

78.5% OF PREVALENT PTS

Distal AVF 88%

Proximal AVF 12%

Elderly, diabetic and dialysis vintage >10y included

Modified from L.Turmel Rodrigues, Marseille 2012, http://www.sfav.org/Publication/SFAV2012/002.pdfModified from L.Turmel Rodrigues, Marseille 2012, http://www.sfav.org/Publication/SFAV2012/002.pdf

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Global median survival 70 month

(50% cardiac death)

0 5 10

Years

75%

50%

25%

Su

rviv

al

> 65y

< 65y

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“NEFROLOGIA INTERVENTISTICA”

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- Creation and maintenance of vascular access for haemodialysis

AVF, AVG, CVC

+/- Color Doppler ultrasound of VA

+/- Radiologic endovascular procedure

- US interventional nephrology: only endovascular/ CVCprocedure -

“NEFROLOGIA INTERVENTISTICA”

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- Nephrology post graduate course

Includes training in vascular access care

Interventional skills formally requested as accademic core curriculum

- AVF-AVG creation and manteinance

- CVC implant

- US (CDU)

Radiologic endovascular procedure not included

“NEFROLOGIA INTERVENTISTICA”

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PERSONAL EXPERIENCE

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“Nephrologist” + Interventional Nephrologist

Vascular access training in Paris

- VA surgery, microsurgery

- Endovascular treatment of complication

Exercing since 2000 (>1000 procedures)

VA care “up to date 2013”:

12 dialysis centres ( 600 patients)

+ nephrology dpts

+ non-ESRD indications

228 procedures/2013

PERSONAL EXPERIENCE

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OPERATIVE PROTOCOL

Out-patient evaluation 1/ week (dedicated database)

First evaluation, follow-up after surgery (1w, 1m, 1y), complications

- Clinical and CDU evaluation

Indication and list for surgery or endovascular procedure

- 2 session /week (surgery/endovascular)

+ emergencies…

PERSONAL EXPERIENCE

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Technical

- preoperative US evaluation

- loco-regional anesthesia (prolonged vasoplegia)

- preventive haemostasis (time, blood, wound sparing)

- operative microscope (because it is microsurgery!)

Clinical

- as distal as possible (snuff-box and ulnobasilic AVF included) :

• eventual secondary endovascular-assisted maturation

• superficialisation (lipectomy) in obese

• prevention of ischemia, high-flow

- avoid CVC as much as possible

PERSONAL “guidelines”

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Future of VA care: challenging task

- Growing ESRD population

- “difficult” patients

- ↑ need of dedicated specialist

- Forearm Fistula First (low rate of complications, easy to treat)

Nefrologia Interventistica: a good way?

CONCLUSION

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…GRAZIE.

[email protected]

www.nefrologiainterventistica.com