sri lanka college of paediatricians - pelc / slcp 1 ......•ecg 10/05/2015 pelc / slcp 8 sri lanka...

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Management of snake bites in children in Sri Lanka 1 Sri Lankan College of Paediatricians PELC / SLCP

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Page 1: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Management of snake

bites in children in Sri

Lanka

1

Sri Lankan College of Paediatricians

PELC / SLCP

Page 2: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Objectives

• Discuss the patterns of envenomation

• Discuss the structured approach to the

management of snake bites

• Identify the venomous snakes in Sri Lanka

PELC / SLCP 2

Page 3: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Case

• 12 year old child sleeping on a mat on floor

• Went to sleep well previous night

• Got up at 4am with abdominal pain

• Given home remedy

• Started vomiting at 6am

10/05/2015 PELC / SLCP 3

Page 4: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

STEPS IN THE MANAGEMENT

•Relive anxiety

•ABCD

•Antivenom administration

•Managing anaphylactic reactions

410/05/2015 PELC / SLCP

Page 5: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

PELS Approach

“The Blueprint”

Triage

Initial Stabilisation

Position

Airway

Breathing

Circulation

Disability

Measurement

Monitoring

Reassess

Directed History and

Examination and Ix –

Reassess

Commence Specific

Treatment

Ongoing Care

10/05/2015 5PELC / SLCP

Page 6: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Directed History & Examination

ASK ABOUT

Event

• Previously normal

• Slept on the floor

Symptoms

• Abdominal pain

• Vomiting

Past history

• Similar incidences in their locality

10/05/2015 PELC / SLCP 6

Page 7: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Examination

•Flange marks on the right ankle

•Little oozing of blood

10/05/2015 PELC / SLCP 7

Page 8: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

INITIAL INVESTIGATIONS

Blood tests

• RBS

• Coagulopathy Ix• Whole Blood Clotting Time

(WBCT)

• Coagulation profile (PT, INR)

• FBC• Polymorphoneuclear

leucocytosis

• Renal –Urea/Creatinine/Serum Electrolytes

• LFT – SGPT/SGOT

• Urinalysis – negative for

blood

• ECG

10/05/2015 PELC / SLCP 8

Page 9: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Sri Lanka Venmous snakes

Antivenin is indicated only for

• Cobra

• Krait

• Russell’s viper

• Saw scaled viper

10/05/2015 PELC / SLCP 9

Page 10: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Antivenin has no benefit for

• Hump nosed viper

• Green pit viper

• Sea snakes

10/05/2015 PELC / SLCP 10

Page 11: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Sri Lanka polyvalent antivenin is

indicated only for

•Witnessed bite + first symptom

•Evidence of systemic

envenomation

10/05/2015 PELC / SLCP 11

Page 12: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

EARLY NON SPECIFIC FEATURES

•Nausea / Vomiting -

•Back ache & Abdominal pain

•Neutrophilia

10/05/2015 PELC / SLCP 12

Page 13: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

COBRASystemic

Neuropathy- Predominant

Coagulopathy

Severe Local envenomation

Swelling with redness and pain

Blistering

Necrosis

10/05/2015 PELC / SLCP 13

Page 14: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Russell’s viper (තිත් ප ොළඟො)Systemic manifestationsCoagulopathy- PredominantNeuropathyRenal

Severe Local envenomationSwelling with redness and pain BlisteringNecrosis

10/05/2015 PELC / SLCP 14

Page 15: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Sri lankan crait

(මුදු කරවලො/ප ොපළොන්කරවලො)

•Neuropathy –

•Respiratory failure

10/05/2015 PELC / SLCP 15

Page 16: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Common crait

(පෙල්කරවලො/දුනු කරවලො/මගමරුවො)

• Neuropathy –

• Respiratory failure

10/05/2015 PELC / SLCP 16

Page 17: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Saw scaled viper

(වැලි ප ොළඟො)

10/05/2015 PELC / SLCP 17

Page 18: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Pre-hospital

management (First aid)

•Reassurance

•Wash and clean the area

•Minimum mobilization

•No tourniquet

•Analgesia with – PCM ( No NSAID)

•Remove rings/ anklets

18PELC / SLCP

Page 19: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Hospital Management

19

• Blue print

• Triage / Position / ABCD

• Assessment of Envenomation

• Specific Management – Indication for Antivenom

• Reassurance

PELC / SLCP

Page 20: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Specific Treatment

• Antivenom

• Indicated

• Precautions

• How many vials

• How fast

• Monitoring

10/05/2015 PELC / SLCP 20

Page 21: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

ANTIVENIN PREPARATION

• Antivenin a total of 10 vials is given as a single dose for

all ages.

• Each vial is reconstituted in 10 ml of Normal Saline.

• Minimize bubbling by avoiding shaking

• Further dilution depending on age and weight

• In older children the reconstituted antivenin can be further

diluted to make total of 400 ml with normal saline.

10/05/2015 PELC / SLCP 21

Page 22: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

ANTIVENIN ADMINISTRATION

• In infants and small children this can be given directly with

an infusion pump.

• First vial to be given over 15 min.

• Complete 10 vials in 1 hour

• Look for signs of anaphylaxis

• Second 10 vials can be considered after 6hrs

depending on the severity of the envenomation.

• More than 20 vials is not encouraged.

10/05/2015 PELC / SLCP 22

Page 23: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Administration of antivenin who

already had allergic reaction • Call for help

• A – B – C – D – E

• Adrenaline sub-cut

• Start antivenin

• Have IM adrenaline ready

• Close observation for allergic reactions

10/05/2015 PELC / SLCP 23

Page 24: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

PELC / SLCP 24

Page 25: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Controversies and challenges

Snake identification

Non specific manifestations

WBCT interpretation

Repeat antivenin

Multi-organ involvement +/-DIC mix with toxin manifestations

Prolonged ventilation in Krait bites

10/05/2015 PELC / SLCP 25

Page 26: Sri Lanka College of Paediatricians - PELC / SLCP 1 ......•ECG 10/05/2015 PELC / SLCP 8 Sri Lanka Venmous snakes Antivenin is indicated only for •Cobra •Krait •Russell’s

Thank you

PELC / SLCP 26