spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple...

5
Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A. McLean, M. Cercignani, K. Wimpey, D.H. Miller, and A.J. Thompson Brain Volume 130(8):2220-2231 July 29, 2007 © 2007 The Author(s)

Upload: octavia-powers

Post on 18-Jan-2018

222 views

Category:

Documents


0 download

DESCRIPTION

Spectra obtained by LCModel analyses of a control (a) and patient (b). O. Ciccarelli et al. Brain 2007;130: © 2007 The Author(s)‏

TRANSCRIPT

Page 1: Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A

Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple

sclerosis

by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A. McLean, M. Cercignani, K. Wimpey, D.H. Miller, and A.J. Thompson

BrainVolume 130(8):2220-2231

July 29, 2007

© 2007 The Author(s)

Page 2: Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A

Cervical cord spectroscopy.

O. Ciccarelli et al. Brain 2007;130:2220-2231

© 2007 The Author(s)

Page 3: Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A

Spectra obtained by LCModel analyses of a control (a) and patient (b).

O. Ciccarelli et al. Brain 2007;130:2220-2231

© 2007 The Author(s)

Page 4: Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A

An example of the spinal cord tracts reconstructed using probabilistic tractography in a control subject.

O. Ciccarelli et al. Brain 2007;130:2220-2231

© 2007 The Author(s)

Page 5: Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis by O. Ciccarelli, C.A. Wheeler-Kingshott, M.A

Graphs showing the correlations between (a) EDSS and m-Ins, (b) 9-hole peg test and Cr, (c) 9-hole peg test and connectivity of the posterior tract and (d) MSWS-12 and Cr.

O. Ciccarelli et al. Brain 2007;130:2220-2231

© 2007 The Author(s)