south pacific simplex p - stryker meded · the pharmacokinetics of simplex tobramycin bone cement....

Implant with conﬁdence Excellent registry results around the world 9 More than 600 published clinical papers Over 50 years of clinical history Excellent implant survivorship 8 > Proven clinical success Available with Tobramycin antibiotic Broader spectrum 1,2 and better elution 3-5 than Gentamicin > Improved patient safety > Decreased risk of revision Dual viscosity and lower porosity Greater penetration 6 and superior fatigue strength than HV cements 7 > Strong cement mantle for excellent implant survivorship Manufacturing quality Allows batch mixing > Predictable working time > Desirable handling characteristics References: 1. Scott CP, Higham PA, Dumbleton JH. Effectiveness of bone cement containing tobramycin. An vitro susceptibility study of 99 organisms found in infected joint arthroplasty. J Bone Joint Surg Br. 1999 May; 81(3):440-443. 2. Sterling GJ, Potter JM, Koerbin G, Crawford S, Crawford R, 2002. The Pharmacokinetics of Simplex Tobramycin Bone Cement. J Bone Joint Surg (Br) 2003; 85-B:646-9. 3. Nelson CL, Griggin FM, Harrison BH, Cooper RE. In vitro elution characteristics of commercially and noncommercially prepared antibiotic PMMA beads. Clin Orthop. 1992 Nov (284): 303-9. 1992 4. Test Reports RD-95-66 and RD-95-59. 5. Murray WR. Use of antibiotic-containing bone cement. Clin Orthop Rel Res 1984 Nov (190):89-95. 6. Rey R, Paiement G,McGannW, et al. A study of intrusion characteristics of low viscosity cement Simplex P and Palacos ® cement in a bovine cancellous bone model. Clin Orthop Rel Res. 1987; 215: 272-278. 7. Linden U. Fatigue properties of bone cement: Comparison of Mixing Techniques. Acta Orthop Scand. 1989:60(4): 431-433. 8. Havelin LI, Espenhaug B, Vollset Se, Engesaeter LB. The effect of the type of cement on the early revision of Charnley total hip prostheses. J Bone J Surg. 1995: 1543-1550. 9. Australian Orthopaedic Association: National Joint Replacement Registry; New Zealand Orthopaedic Association: The New Zealand Joint Registry; Norwegian Nasjonalt Register for Leddproteser: The Norwegian Arthroplasty, Cruciate Ligament and Hip Fracture Registers; National Joint Registry for England and Wales A healthcare professional must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. The information presented is intended to demonstrate the breadth of Stryker product offerings. A healthcare professional must always refer to the package insert, product label and/or instructions for use before using any Stryker product. Simplex ™ P Bone Cement Simplex TM P Trusted Reliable Consistent FLAME_STRY341_09/12 Experience the difference South Pacific Stryker Australia | 8 Herbert Street, St Leonards NSW 2065

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Page 1: South Pacific Simplex P - Stryker MedEd · The Pharmacokinetics of Simplex Tobramycin Bone Cement. J Bone Joint Surg (Br) 2003; 85-B:646-9. Nelson CL, Griggin FM, Harrison BH, Cooper

Implant with confidenceExcellent registry results around the world9

More than 600 published clinical papersOver 50 years of clinical history

Excellent implant survivorship8

> Proven clinical success

Available with Tobramycin antibioticBroader spectrum1,2 and better elution3-5 than Gentamicin

> Improved patient safety> Decreased risk of revision

Dual viscosity and lower porosity

Greater penetration6 and superior fatigue strength than HV cements7

> Strong cement mantle for excellent implant survivorship

Manufacturing quality

Allows batch mixing> Predictable working time> Desirable handling characteristics

References:1. Scott CP, Higham PA, Dumbleton JH. Effectiveness of bone cement containing tobramycin. An vitro susceptibility study of 99 organisms found in infected joint arthroplasty. J Bone Joint Surg Br. 1999 May; 81(3):440-443. 2. Sterling GJ, Potter JM, Koerbin G, Crawford S, Crawford R, 2002. The Pharmacokinetics of Simplex Tobramycin Bone Cement.J Bone Joint Surg (Br) 2003; 85-B:646-9. 3. Nelson CL, Griggin FM, Harrison BH, Cooper RE. In vitro elution characteristics of commercially and noncommercially preparedantibiotic PMMA beads. Clin Orthop. 1992 Nov (284): 303-9. 1992 4. Test Reports RD-95-66 and RD-95-59. 5. Murray WR. Use of antibiotic-containing bone cement. ClinOrthop Rel Res 1984 Nov (190):89-95. 6. Rey R, Paiement G,McGannW, et al. A study of intrusion characteristics of low viscosity cement Simplex P and Palacos® cement in abovine cancellous bone model. Clin Orthop Rel Res. 1987; 215: 272-278. 7. Linden U. Fatigue properties of bone cement: Comparison of Mixing Techniques. Acta Orthop Scand.1989:60(4): 431-433. 8. Havelin LI, Espenhaug B, Vollset Se, Engesaeter LB. The effect of the type of cement on the early revision of Charnley total hip prostheses. J Bone J Surg.1995: 1543-1550. 9. Australian Orthopaedic Association: National Joint Replacement Registry; New Zealand Orthopaedic Association: The New Zealand Joint Registry; NorwegianNasjonalt Register for Leddproteser: The Norwegian Arthroplasty, Cruciate Ligament and Hip Fracture Registers; National Joint Registry for England and Wales

A healthcare professional must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. The information presented is intended to demonstrate the breadth of Stryker product offerings. A healthcare professional must always refer to the package insert, product label and/or instructions for use before using any Stryker product.

Simplex

™ PBone Cement

SimplexTM PTrustedReliable

Consistent

FLA

_STR

Y34

1_09

/12

Experience the difference

South Pacific

Stryker Australia | 8 Herbert Street, St Leonards NSW 2065