some usfda respite for sun; not yet for...

25
ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update Some USFDA respite for Sun; not yet for DRL… The USFDA has lifted the import alert from Sun’s Mohali (erstwhile Ranbaxy facility) facility and removed the same from the Official Action Initiated (OAI) status. This proposed action will clear the path for Sun Pharma to supply approved products from the Mohali facility to the US market, subject to normal USFDA regulatory requirements. The USFDA had taken action against the Mohali facility in 2013 when it ordered the facility to be fully subject to Ranbaxy’s consent decree of permanent injunction. On the other hand, Dr Reddy's received 13 Form-483 observations from the USFDA for Duvvada (Vizag) oncology formulation unit. The company has to respond with a corrective action plan. Duvvada was one of the three plants, which received a warning letter on November 2015, of which Srikakulam (API unit) is the major contributor to US revenues. In an important development, Syngene has tied up with HerbalLife Nutrition, to develop nutrition based products that can be sold by the company in India. This is the fifth dedicated centre for Syngene. Biocon’s partner Mylan has settled Herceptin patent dispute with Roche. As per the terms, Roche will grant the partners a global license (excluding Japan, Brazil and Mexico) for Herceptin in return for Mylan's promise to back off of two challenges pending at the US Patent and Trademark Office. On the innovative pipeline front, Glenmark has received USFDA clearance of IND for GSP 304. It plans to initiate clinical development with a Phase II study in subjects with mild to moderate COPD. Finally, the Indian pharmaceutical market (IPM) grew 7.1% YoY to | 8980 crore for in February. IPM growth was mainly driven by volumes increase – 2.1%, new product launches – 3.3% and price hikes- 1.4%. On a MAT basis, IPM growth was at 10.2% YoY to | 110149 crore. Positive news on cGMP front yet to outweigh other apprehensions Almost all players with US franchisee from the I-direct universe have witnessed USFDA inspection/re-inspection in the past six months with higher number of positive outcomes. However, this has done little to lift sentiments as the pricing pressure in the US base business, ranging from high single digit to low double digit continues will weigh. Similarly, the strengthening of the rupee vis-à-vis the US dollar after recent events is also likely to weigh in the near term. Apart from this, other issues/uncertainty in the US like pricing probe by the Department of Justice (DoJ), adapting to the bidding process and imposition of border tax on imported drugs are other near term overhangs. Front loading of investments, although useful for long term growth strategy, is also likely to impact near term profitability. For the time being, attractive valuations and decent growth expectations for FY18, FY19 are likely to be on the backburner due to these apprehensions. In the long run, however, we expect the earnings momentum to pick up on the back of incremental product launches largely on speciality, biosimilar and injectables front in the US besides normalising of Indian formulations growth. We expect healthcare universe revenues, EBITDA and PAT to grow at a CAGR of 11%, 11% and 13%, respectively, in FY16-19E. The growth will be steered by US (~10% CAGR over FY16-19E) and Indian formulations (~13% CAGR over FY16-19E). Health Check Sector View Neutral Index Performance as on March 15, 2017 Return (%) 1M 3M YTD 1Y CNX 500 4 13 13 27 Nifty 4 12 12 22 NSE Pharma 3 1 4 -6 Return (%) Stocks Performance Mcap Company 1M 3M YTD 1Y 15-Mar Sun Pharma.Inds. 9 10 13 -15 170345 Lupin 1 -1 -2 -17 65551 Cipla 3 6 6 13 48429 Dr Reddy's Labs -6 -11 -10 -13 45697 Cadila Health. 3 18 24 31 45398 Aurobindo Pharma 4 -1 3 -5 40175 Glenmark Pharma. -3 -3 1 9 25385 Torrent Pharma. 9 5 4 9 23160 Glaxosmit Pharma 1 0 -1 -19 22904 Biocon 2 14 18 137 22420 Divi's Lab. 6 -33 -1 -20 20599 Apollo Hospitals -2 1 4 -10 17050 Ajanta Pharma 0 -3 -1 27 15524 Natco Pharma 3 33 37 66 13816 Jubilant Life 15 27 27 113 12755 Alembic Pharma 12 -2 3 -1 11596 Strides Arcolab -4 4 8 8 10251 Syngene Int. 3 -13 -9 30 10227 Wockhardt 10 10 14 -22 8325 Pfizer -1 -7 -6 2 7873 Ipca Labs. 6 2 4 4 7015 Unichem Labs. 5 6 11 30 2583 Indoco Remedies -2 -2 -1 -6 2368 Return (%) Market cap in | crore Global Index Performance Company 1M 3M YTD 1Y 3Y 5Y S&P 500 Pharm Index (US) 4 9 10 14 9 16 NASDAQ Biotechnology (US) 3 11 14 21 6 21 S&P Pharmaceuticals (US) 0 6 8 9 -1 13 DJ Pharma and Biotech (US) 4 10 11 17 8 17 DJ STOXX Healthcare (EU) 3 8 7 10 11 15 TOPIX Pharma Index (Japan) 1 5 3 3 16 18 MSCI World Pharm & Biotech 3 10 10 10 5 14 Bl World Pharma index 3 9 9 8 4 12 BI Global Spectalty-Generic Pharm -10 -6 -7 -32 -12 4 NSE Pharma 3 1 4 -5 12 18 Return (%) Research Analyst Siddhant Khandekar [email protected] Mitesh Shah [email protected]

Upload: hoangtuyen

Post on 28-May-2018

223 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

March 16, 2017

Monthly Update

Some USFDA respite for Sun; not yet for DRL… The USFDA has lifted the import alert from Sun’s Mohali (erstwhile Ranbaxy facility) facility and removed the same from the Official Action Initiated (OAI) status. This proposed action will clear the path for Sun Pharma to supply approved products from the Mohali facility to the US market, subject to normal USFDA regulatory requirements. The USFDA had taken action against the Mohali facility in 2013 when it ordered the facility to be fully subject to Ranbaxy’s consent decree of permanent injunction. On the other hand, Dr Reddy's received 13 Form-483 observations from the USFDA for Duvvada (Vizag) oncology formulation unit. The company has to respond with a corrective action plan. Duvvada was one of the three plants, which received a warning letter on November 2015, of which Srikakulam (API unit) is the major contributor to US revenues. In an important development, Syngene has tied up with HerbalLife Nutrition, to develop nutrition based products that can be sold by the company in India. This is the fifth dedicated centre for Syngene. Biocon’s partner Mylan has settled Herceptin patent dispute with Roche. As per the terms, Roche will grant the partners a global license (excluding Japan, Brazil and Mexico) for Herceptin in return for Mylan's promise to back off of two challenges pending at the US Patent and Trademark Office. On the innovative pipeline front, Glenmark has received USFDA clearance of IND for GSP 304. It plans to initiate clinical development with a Phase II study in subjects with mild to moderate COPD. Finally, the Indian pharmaceutical market (IPM) grew 7.1% YoY to | 8980 crore for in February. IPM growth was mainly driven by volumes increase – 2.1%, new product launches – 3.3% and price hikes- 1.4%. On a MAT basis, IPM growth was at 10.2% YoY to | 110149 crore. Positive news on cGMP front yet to outweigh other apprehensions Almost all players with US franchisee from the I-direct universe have witnessed USFDA inspection/re-inspection in the past six months with higher number of positive outcomes. However, this has done little to lift sentiments as the pricing pressure in the US base business, ranging from high single digit to low double digit continues will weigh. Similarly, the strengthening of the rupee vis-à-vis the US dollar after recent events is also likely to weigh in the near term. Apart from this, other issues/uncertainty in the US like pricing probe by the Department of Justice (DoJ), adapting to the bidding process and imposition of border tax on imported drugs are other near term overhangs. Front loading of investments, although useful for long term growth strategy, is also likely to impact near term profitability. For the time being, attractive valuations and decent growth expectations for FY18, FY19 are likely to be on the backburner due to these apprehensions. In the long run, however, we expect the earnings momentum to pick up on the back of incremental product launches largely on speciality, biosimilar and injectables front in the US besides normalising of Indian formulations growth. We expect healthcare universe revenues, EBITDA and PAT to grow at a CAGR of 11%, 11% and 13%, respectively, in FY16-19E. The growth will be steered by US (~10% CAGR over FY16-19E) and Indian formulations (~13% CAGR over FY16-19E).

Health CheckSector View

Neutral

Index Performance as on March 15, 2017

Return (%) 1M 3M YTD 1Y

CNX 500 4 13 13 27

Nifty 4 12 12 22

NSE Pharma 3 1 4 -6

Return (%)

Stocks Performance Mcap

Company 1M 3M YTD 1Y 15-Mar

Sun Pharma.Inds. 9 10 13 -15 170345

Lupin 1 -1 -2 -17 65551

Cipla 3 6 6 13 48429

Dr Reddy's Labs -6 -11 -10 -13 45697

Cadila Health. 3 18 24 31 45398

Aurobindo Pharma 4 -1 3 -5 40175

Glenmark Pharma. -3 -3 1 9 25385

Torrent Pharma. 9 5 4 9 23160

Glaxosmit Pharma 1 0 -1 -19 22904

Biocon 2 14 18 137 22420

Divi's Lab. 6 -33 -1 -20 20599

Apollo Hospitals -2 1 4 -10 17050

Ajanta Pharma 0 -3 -1 27 15524

Natco Pharma 3 33 37 66 13816

Jubilant Life 15 27 27 113 12755

Alembic Pharma 12 -2 3 -1 11596

Strides Arcolab -4 4 8 8 10251

Syngene Int. 3 -13 -9 30 10227

Wockhardt 10 10 14 -22 8325

Pfizer -1 -7 -6 2 7873

Ipca Labs. 6 2 4 4 7015

Unichem Labs. 5 6 11 30 2583

Indoco Remedies -2 -2 -1 -6 2368

Return (%)

Market cap in | crore

Global Index Performance

Company 1M 3M YTD 1Y 3Y 5Y

S&P 500 Pharm Index (US) 4 9 10 14 9 16

NASDAQ Biotechnology (US) 3 11 14 21 6 21

S&P Pharmaceuticals (US) 0 6 8 9 -1 13

DJ Pharma and Biotech (US) 4 10 11 17 8 17

DJ STOXX Healthcare (EU) 3 8 7 10 11 15

TOPIX Pharma Index (Japan) 1 5 3 3 16 18

MSCI World Pharm & Biotech 3 10 10 10 5 14

Bl World Pharma index 3 9 9 8 4 12

BI Global Spectalty-Generic Pharm -10 -6 -7 -32 -12 4

NSE Pharma 3 1 4 -5 12 18

Return (%)

Research Analyst

Siddhant Khandekar [email protected] Mitesh Shah [email protected]

Page 2: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 2

Regulatory approvals

Exhibit 1: Summary of USFDA approvals for Feb, 2017 [5

Company Drug Name Therapeutic Area Innovator company Generic Version of Market SizeLupin Triamcinolone Acetonide Derma Mylan NA US$ 55.7 millionAurobindo Pharma Pravastatin Sodium CVS Bristol Myers Squibb Pravachol NAAurobindo Pharma Nexesta Fe (norethindrone and ethinyl estradiol) OC APIL Femcon FE NACipla Oxaliplatin injection Anti-Cancer Sanofi Eloxatin NALupin Moxifloxacin Hydrochloride Anti-Infective Bayer Avelox NALupin Hydrocodone Bitartrate and Homatropine Methylbromide Respiratory Endo Pharma Hycodan NACadila Healthcare Clobetasol Propionate Spray Dermatology Galderma labs Clobex NACadila Healthcare Fluconazole Tablets Anti-Infective Pfizer Diflucan NAAurobindo Pharma Fesoterodine Fumarate Urology Pfizer Toviaz NAAurobindo Pharma Rabeprazole Sodium tablets Anti-ulcerant J&J Aciphex NACadila Healthcare Linezolid Anti-Bacterial Harmacia Zyvox NALupin Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate GI Braintree Lab Suprep Bowel Prep Kit US$ 207.2 millionJubilant life Itraconazole Anti- fungal Janssen Pharma Sporanox US$ 42 millionLupin Oxycodone and Acetaminophen Tablets Pain Management Vintage Pharma Percocet US$ 838.7 millionAurobindo Pharma Etomidate Injection Anesthesia Hospira Amidate NATaro Brompheniramine; Dextromethorphan; Pseudoephedrine Cough Syrup Wockhardt Bromfed DM NAAurobindo Pharma Nevirapine Anti-retroviral Boehringer Ingelheim Viramune NADr Reddy's Lab Progesterone OC Virtus Pharma Prometrium NA

Tentative ApprovalsCompany Drug Name Therapeutic Area Innovator company Generic Version of Market SizeTaro Pharma Diclofenac Sodium 2% Anti-Inflammatory Nuvo Res Pennsaid US$ 13.3 millionAurobindo Pharma Tadalafil CVS Eli Lilly Adcirca NATaro Pharma Clobetasol Propionate Spray Dermatology Galderma labs Clobex NA

Final Approvals

CNS: Central Nervous System; CVS: Cardiovascular, GI: Gastro Intestinal, OC: Oral Contraceptive, NA: Not available; Source: USFDA, ICICIdirect.com Research

M&As, demergers, tie-ups and JVs

Dr Reddy’s acquires Kolkata based NBFC Dr Reddy's has completed the acquisition of 100% stake in Imperial Credit Pvt Ltd, a non-banking finance company, based in Kolkata for a consideration of | 2.05 crore. The acquisition was consummated on receipt of regulatory approvals. The company has proposed to undertake the group's captive financial activities through this entity. Cipla divests animal health business in South Africa Cipla has entered into agreements for divesting its animal health business in South Africa and Sub-Saharan Africa (subject to CCI SA approval) for ZAR 375 million (~| 192 crore) with potential revision linked to FY17 performance along with customary adjustment. Price cuts, new launches, recalls, approvals

NPPA caps prices of 18 drugs National Pharmaceutical Pricing Authority (NPPA) has capped the prices of four essential drugs and revised 14 more, including ones used for treatment of fungal infections and hypertension.

NPPA lowers prices of cancer drugs NPPA has slashed prices of some cancer drugs by up to 86%. From the I-direct coverage universe perspective, the list includes two drugs of Dr Reddy’s (Grafeel and Levin) and Natco Pharma (Veenat). Lawsuits, court rulings, settlements, regulatory issues

USFDA clears Alembic Pharma Baroda facility USFDA has cleared the Alembic Pharma bioequivalence facility at Baroda without any observations. The USFDA inspected this facility from March 6 to March 10, 2017.

Page 3: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 3

Glenmark’s Ankaleshwar plant receives EIR from USFDA Glenmark’s Ankaleshwar API facility has received an Establishment inspection report (EIR) from USFDA. The USFDA had issued four form 483 observations after the inspection of the facility in December 2016. Mylan, Biocon settle Herceptin patent challenge with Roche Biocon’s partner Mylan has settled its Herceptin patent dispute with Roche. As per the terms, Roche will grant the partners a global license (excluding Japan, Brazil and Mexico) for Herceptin in return for Mylan's promise to back off of two challenges pending at the US Patent and Trademark Office. Dr Reddy’s receives 13 observations for Duvvada formulation unit Dr Reddy’s Labs has got 13 observations from USFDA for Duvvada oncology formulation unit. The company has to respond with a corrective action plan and implement it quickly Cadila Healthcare gets marketing rights for Trokendi XR Cadila Healthcare has finalised an agreement with Supernus Pharma to settle all outstanding patent litigation related to Trokendi XR (extended-release capsules) and granted Cadila a license to market the drug from 2023. Lupin to acquire Pulmojet As per media sources, Lupin is in talks with Sanofi arm Zentiva to acquire Pulmojet, its dry powder inhalation brand. Pulmojet was acquired by Zentiva from Siegfried in 2010 Unichem gets two observations for its Ghaziabad facility Unichem Lab’s formulation manufacturing facility in Ghaziabad has received two form 483 observations USFDA. USFDA has inspected this facility between February 24, 2016 and March 3, 2016. Syngene enters into R&D partnership with Herbalife Syngene has tied up with HerbalLife Nutrition, to develop nutrition based products that can be sold by the company in India. This is the fifth dedicated centre and second for nutrition research by Syngene. USFDA to lift import ban on Sun’s Mohali plant USFDA has lifted the import alert from Sun’s Mohali facility (erstwhile Ranbaxy facility) and removed the facility from the Official Action Initiated (OAI) status. This proposed action will clear the path for Sun Pharma to supply approved products from the Mohali facility to the US market, subject to normal USFDA regulatory requirements. The Mohali facility was inherited by Sun as part of its acquisition of Ranbaxy in 2015. The USFDA had taken action against the Mohali facility in 2013 when it ordered the facility to be fully subject to Ranbaxy’s consent decree of permanent injunction. However, certain conditions of the consent decree will continue to be applicable to the Mohali facility. This development illustrates Sun Pharma’s commitment to work closely with the USFDA and strive for 100% cGMP compliance at its manufacturing facilities.

Others

Glenmark clears phase 2 trials for its NCE Glenmark has received USFDA clearance of IND for GSP 304. It plans to initiate clinical development with a Phase 2 study of GSP 304 in subjects with mild to moderate COPD.

Page 4: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 4

Exhibit 2: Patent litigations (12 months) [5

Month Innovator ANDA Filer Brand Name API Used for Mar-16 Shire Canada Lupin Daliresp Roflumilast RespiratoryMar-16 Daiichi Sankyo Torrent Pharma Benicar Olmesartan Anti-depressantApr-16 Daiichi Sankyo Alembic Pharma Benicar Olmesartan Anti-depressantMay-16 Daiichi Sankyo Aurobindo Pharma Benicar Olmesartan Anti-depressantJun-16 Apicore Aurobindo Pharma Lymphazurin isosulfan blue lymphatic imaging agentJun-16 UCB, Inc. Aurobindo Pharma Vimpat lacosamide partial-onset seizuresJun-16 Gilead Aurobindo Pharma Emtriva emtricitabine HIVJun-16 Janssen Biotech Glenmark Pharma Zytiga abiraterone OncologyJun-16 Sanofi-Aventis Cadila Healthcare Mozobil plerixafor non-Hodgkin's lymphomaJul-16 Sanofi-Aventis Cadila Healthcare Mozobil plerixafor non-Hodgkin's lymphomaJul-16 Roche Cadila Aloxi palonosetron hydrochloride prevention of acute nausea Jul-16 AstraZeneca AB Aurobindo Nexium 24HR esomeprazole magnesium treatment of acid refluxJul-16 Hyperion Therapeutics Lupin Ravicti Glycerol Phenylbutyrate urea cycle disordersJul-16 Gilead Sciences, Inc. Aurobindo Truvada emtricitabine / tenofovir disoproxil fumarate HIVAug-16 Lupin InvaGen Pharma Antara fenofibrate hypercholesterolemiaAug-16 Reckitt Benckiser Inc. Sun Pharma Mucinex guaifenesin / pseudoephedrine hydrochloride bronchial congestionAug-16 Dexcel Aurobindo Prilosec Omeprazole HeartburnSep-16 Pfizer Aurobindo Toviaz fesoterodine fumarate overactive bladderSep-16 Arena Pharma Lupin Belviq lorcaserin weight lossSep-16 Brigham and Women's Hospital InSun Pharma Sensipar cinacalcet hydrochloride hyper parathyroidismSep-16 Brigham and Women's Hospital InStrides Inc. Sensipar cinacalcet hydrochloride hyper parathyroidismSep-16 Brigham and Women's Hospital InCipla Sensipar cinacalcet hydrochloride hyper parathyroidismSep-16 Eli Lilly and Co., ICOS Corp. Cipla Cialis tadalafil erectile dysfunctionSep-16 Brigham and Women's Hospital InAurobindo Sensipar cinacalcet hydrochloride hyper parathyroidismSep-16 Eli Lilly and Co., ICOS Corp. Alembic Pharma Cialis tadalafil erectile dysfunctionOct-16 Amgen Inc. Ajanta Pharma Sensipar cinacalcet calcium reducerOct-16 Amgen Inc. Dr Reddy's Lab Sensipar cinacalcet calcium reducerOct-16 UCB, Inc. Cadila Healthcare Vimpat lacosamide partial-onset seizuresOct-16 Astellas Pharma Lupin Myrbetriq mirabegron overactive bladderOct-16 Astellas Pharma Cadila Healthcare Myrbetriq mirabegron overactive bladderOct-16 Astellas Pharma Aurobindo Pharma Myrbetriq mirabegron overactive bladderOct-16 AstraZeneca AB Glenmark Pharma Nexium 24HR esomeprazole magnesium treatment of acid refluxOct-16 Celgene Corp. Dr Reddy's Lab Revlimid lenalidomide multiple myelomaOct-16 Otsuka Pharma Zydus Pharma Abilify Aripiprazole SchizophreniaOct-16 Onyx Therapeutics Cipla Kyprolis carfilzomib multiple myelomaOct-16 Eli Lilly Cipla Axiron Hypogonadism TestosteroneOct-16 Galderma Lab Sun Pharma Oracea doxycycline infectionsOct-16 Eli Lilly Cipla Axiron Hypogonadism TestosteroneOct-16 Indoco Remedies Zydus Pharma Abilify Aripiprazole SchizophreniaOct-16 Eli Lilly Cipla Axiron Hypogonadism TestosteroneNov-16 Onyx Therapeutics Dr Reddy's Lab Kyprolis carfilzomib multiple myelomaNov-16 Onyx Therapeutics Cadila Kyprolis carfilzomib multiple myelomaNov-16 Indoco Remedies Zydus Pharma Abilify Aripiprazole SchizophreniaNov-16 UCB Inc Cadila Neupro rotigotine ParkinsonNov-16 Amarin Pharma Dr Reddy's Lab Vascepa icosapent ethy hypertri- glyceridemiaNov-16 Medicis Pharma Dr Reddy's Lab Solodyn minocycline infectionsDec-16 Sanofi-Aventis Torrent Pharma AUBAGIO teriflunomide multiple sclerosisDec-16 AstraZeneca AB Cipla Nexium 24HR esomeprazole treatment of acid refluxDec-16 Sanofi-Aventis Glenmark AUBAGIO teriflunomide multiple sclerosisDec-16 Sanofi-Aventis Alembic Pharma AUBAGIO teriflunomide multiple sclerosisDec-16 Wyeth Pharma Alembic Pharma BOSULIF bosutinib leukemiaDec-16 Sanofi-Aventis Aurobindo AUBAGIO teriflunomide multiple sclerosisDec-16 Eli Lilly and Co., ICOS Corp. Ajanta Pharma CIALIS tadalafil erectile dysfunctionDec-16 Astellas Pharma Cadila XTANDI enzalutamide prostate cancerDec-16 Cephalon, Inc. Cipla Abraxane paclitaxel breast cancerJan-17 Sanofi-Aventis Biocon AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Teva Pharma AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis MSN Laboratories AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Hetero Labs AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Zydus Pharma (USA) AUBAGIO teriflunomide multiple sclerosisJan-17 AbbVie Inc Aurobindo Pharma KALETRA ritonavir HIVJan-17 Novartis AG Aurobindo Pharma GILENYA fingolimod multiple sclerosisJan-17 Novartis AG Aurobindo Pharma GILENYA fingolimod multiple sclerosisJan-17 Shionogi Inc Aurobindo Pharma FORTAMET metformin Type 2 diabetesJan-17 Dow Pharma Taro Pharma ONEXTON cindamycin phosphate, benzoyl peroxide AcneJan-17 Aptalis Pharma Zydus Pharma (USA) CANASA mesalamine Ulcerative proctitisFeb-17 Pfizer Inc Torrent Pharma TOVIAZ glatiramer acetate IncontinenceFeb-17 Biomarin Pharma Dr. Reddy's Lab KUVAN sapropterin PhenylketonuriaFeb-17 AstraZeneca AB Dr. Reddy's Lab FASLODEX fulvestrant Breast cancerFeb-17 iCeutica Pty Ltd Lupin Ltd VIVLODEX meloxicam Osteoarthritis painFeb-17 Pfizer Inc Sun Pharma XELJANZ XR tofacitinib citrate Rheumatoid arthritis

Source: Bloomberg, ICICIdirect.com Research

Page 5: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 5

IPM grows 7% YoY in February as NLEM, DEMO weigh • The Indian pharmaceutical market (IPM) grew 7.1% YoY to | 8980 crore

for February. IPM growth was mainly driven by volumes increase – 2.1%, new product launches – 3.3% and price hikes- 1.4%

• The fixed dosage combination (FDCs) related market de-grew 34.9% resulting in a 1.3% squeeze to overall growth

• Drugs under NLEM list declined 8% to | 942 crore while non-NLEM drugs posted growth of 9.6% to | 7637 crore. Volume growth in NLEM and non-NLEM was 1.8% and -0.3%, respectively

• Among companies under I-direct coverage, Ajanta Pharma, Cadila, Glenmark, Natco, Torrent Pharma, Unichem and Sun have registered higher than industry growth

• Therapy wise, 13 therapies have outpaced IPM growth. Notable among them with growth rates- anti-diabetic – 16.1%, gynaecology – 9.7% and derma – 12.0%. On the other hand, anti-Infectives declined 4.2% YoY and anti-malarials declined 18.2% YoY

• In all, 180 new brands were launched in February 2017 • On a MAT basis, IPM growth was at 10.2% YoY to | 110149 crore • Domestic and MNC companies have grown 7.1%in February 2017 Exhibit 3: Domestic formulations - growth trend [

13.5

8.1

5.5 7.

8

7.7

9.7 11

.0

17.4

13.5

20

15.7

10.1

7.1

-5

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 4: Companies growth in domestic market in February, 2017

3.6

10.6

15.5

0.9

8.29.4

-2.6

3.3

-3.3

13.5

6.33.0 5.4

4.8

8.1 9.9

-5

0

5

10

15

20

Aja

nta

Ale

mbi

c

Bioc

on

Cadi

la

Cipl

a

DRL

Glen

mar

k

GSK

Phar

ma

Indo

co

Ipca

Lab

s

Lupi

n

Nov

artis

Pfize

r

Sun

Phar

ma

Torre

nt

Unic

hem

(%)

Source: AIOCD data base, ICICIdirect.com Research

Therapy wise performance (| crore) Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)Anti-Infectives 1209 1262 -4.2 1192 1.4Cardiac 1150 1067 7.8 1180 -2.5GI 1026 952 7.7 1028 -0.2Vitamins 757 714 6.1 759 -0.2Anti Diabetic 813 700 16.1 834 -2.5Respiratory 714 708 0.9 761 -6.2Pain 597 555 7.5 601 -0.8Neuro 554 531 4.4 571 -2.9Derma 547 488 12.0 563 -2.8Gynaecological 478 436 9.7 472 1.3Anti-Neoplastics 198 157 25.7 210 -5.9Ophthal 163 157 3.8 158 3.0Vaccines 167 130 29.2 162 3.3Hormones 157 143 9.8 158 -0.7Urology 104 93 12.0 103 0.4Blood Related 110 87 25.9 108 1.9Others 112 84 33.7 107 4.5Sex Stimulants 60 50 20.9 59 2.0Anti Malarials 27 33 -18.2 21 26.4Stomatologicals 38 38 -2.3 40 -5.8

Source: AIOCD data base

Top brands in Indian pharma market Brand Company Therapy Feb' 17 YoY (%)Mixtard Abbott Anti Diabetic 508.0 -1.4Glycomet Gp USV Anti Diabetic 402.0 22.2Spasmo ProxyvoWockhardt GI 369.0 16.3Lantus Sanofi India Anti Diabetic 337.0 27.1Galvus Met Novartis Anti Diabetic 319.0 21.4Liv 52 Himalaya GI 293.0 13.0Augmentin GSK Anti-Infectives 283.0 -12.3Monocef Aristo Anti-Infectives 278.0 -2.6Janumet Msd Anti Diabetic 276.0 15.3Clavam Alkem Anti-Infectives 275.0 13.6

Source: AIOCD data base Industry acute to chronic therapy ratio percentage…

Acute, 52850, 48.0%

Chronic, 34815, 31.6%

Sub-Chronic, 22484, 20.4%

Source: AIOCD data base; As per AIOCD MAT Feb 2017

Page 6: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 6

Sun Pharmaceuticals

507090

110130150

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Sun Pharma

Source: NSE, ICICIdirect.com Research Exhibit 5: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

20.7

12.4

5.4

5.3

3.3 7.

7

20.5

17.3

13.8

20.5

9.5

9.5

8.1

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Sun Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 6: Market share in Indian formulations market

8.6 8.7 8.6 8.6 8.6 8.5 8.4 8.4 8.58.8 8.6 8.68.7

6.06.57.07.58.08.59.09.5

10.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Sun Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 7: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Volini Pain 18.4 17.3 6.4 19.1 -3.7

Rosuvas Cardiac 18.2 15.3 19.0 16.7 9.0

Istamet Anti Diabetic 17.4 14.4 20.8 17.8 -2.2

Gemer Anti Diabetic 16.0 13.3 20.3 16.5 -3.0

Levipil Neuro 14.5 13.0 11.5 14.6 -0.7

Susten Gynaecological 13.8 13.5 2.2 14.0 -1.4

Pantocid Gastro Intestinal 11.5 11.5 0.0 11.6 -0.9

Revital H Vitamins 11.4 8.8 29.5 11.1 2.7

Moxclav Anti-Infectives 10.2 7.2 41.7 9.5 7.4

Pantocid Dsr Gastro Intestinal 9.8 9.8 0.0 9.8 0.0

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 8: Contribution of therapies to domestic sales (MAT Feb’17)

z

Cardiac, 30%

Neuro , 27%

Gastro Intestinal, 18%

Anti-Infectives, 17%

Derma, 8%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 9: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 149.3 134.9 10.7 150.4 -0.7

Neuro 135.9 126.6 7.3 138.7 -2.0

Gastro Intestinal 89.2 84.4 5.7 88.8 0.5

Anti-Infectives 84.2 85.1 -1.1 78.3 7.5

Derma 42.9 30.7 39.7 76.3 -43.8

Anti Diabetic 73.9 66.4 11.3 54.0 36.9

Respiratory 31.0 28.4 9.2 43.7 -29.1

Pain 51.5 50.6 1.8 33.3 54.7

Gynaecological 29.6 30.9 -4.2 30.5 -3.0

Vitamins 31.4 27.2 15.4 30.0 4.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 3753, 39.7%

Chronic, 4387, 46.4%

Sub-Chronic, 1318, 13.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

18%

9%

7%

10%

56%

Top 10 11 to 20 21 to 30 31 to 50 Others

Page 7: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 7

Cipla

Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Cipla

Source: NSE, ICICIdirect.com Research

Exhibit 10: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

11.6

3.7

2.1 5.

8

8.6

19.8

19.5

10.2

6.3

10.7

2.7

5.1

3.3

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 11: Market share in Indian formulations market

5.1

4.8

5.0

4.6 4.6

4.94.8

4.7 4.74.8

4.94.8

4.9

4.0

4.2

4.4

4.6

4.8

5.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 12: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Foracort Respiratory 19.2 16.8 14.3 19.8 -3.0

Duolin Respiratory 15.1 12.5 20.8 16.6 -9.0

Budecort Respiratory 12.7 15.8 -19.6 13.1 -3.1

Seroflo Respiratory 12.5 11.1 12.6 13.7 -8.8

Asthalin Respiratory 12.2 12.1 0.8 12.9 -5.4

Amlopres At Cardiac 9.4 4.6 104.3 6.1 54.1

Montair Lc Respiratory 8.9 7.5 18.7 9.4 -5.3

Aerocort Respiratory 8.8 8.2 7.3 8.9 -1.1

Cefbact T Anti-Infectives 8.6 0.9 855.6 0.2 4200.0

Dytor Cardiac 7.4 6.0 23.3 7.5 -1.3

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 13: Contribution of therapies to domestic sales (MAT Feb’17)

Respiratory, 31%

Anti-Infectives, 25%

Cardiac, 12%

Gastro Intestinal, 8%

Urology, 5%

Other, 19%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 14: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (% ) Jan' 17 M oM (%)

Respiratory 139.6 134.3 3.9 149.6 - 6.7

Ant i- Infect ives 107.8 118.3 -8.9 99.0 8.9

Cardiac 58.6 48.2 21.6 55.1 6.4

Gas tro Int es tinal 31.7 30.1 5.3 28.2 12.4

Urology 21.7 18.0 20.6 21.8 - 0.5

Neuro 16.5 14.9 10.7 16.8 - 1.8

Ophthal 14.6 13.6 7.4 14.7 - 0.7

Pain 11.9 12.3 -3.3 12.2 - 2.5

Derma 10.3 10.6 -2.8 10.0 3.0

Gynaecological 6.8 7.6 -10.5 7.1 - 4.2

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 2401, 45.5%

Chronic, 2196, 41.6%

Sub-Chronic,

685, 13.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

24%

12%

9%12%

43%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 8: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 8

Dr. Reddy’s Labs

Stock Performance) Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Dr. Reddys

Source: NSE, ICICIdirect.com Research Exhibit 15: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

31.3

6.3

-1.6

3.9

1.5

5.2

17.3

22.6

7.5

4.9

-2.7 0.5

-3.3-5

0

5

10

15

20

25

30

35

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Dr. Reddys Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 16: Market share in Indian formulations market

2.62.3 2.1 2.1 2.3 2.2 2.3 2.4 2.2 2.3 2.4 2.3 2.3

0.6

1.1

1.6

2.1

2.6

3.1

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Dr. Reddys Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 17: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Omez D Gastro Intestinal 9.0 9.1 -1.1 8.3 8.4

Omez Gastro Intestinal 8.7 11.6 -25.0 9.2 -5.4

Atarax Respiratory 5.4 4.1 31.7 5.3 1.9

Razo D Gastro Intestinal 5.3 4.3 23.3 5.3 0.0

Econorm Gastro Intestinal 5.1 7.4 -31.1 4.7 8.5

Stamlo Cardiac 5.0 6.8 -26.5 5.5 -9.1

Razo Gastro Intestinal 4.6 4.2 9.5 4.8 -4.2

Reditux Anti-Neoplastics 4.3 3.4 26.5 3.9 10.3

Ketorol Pain 4.2 3.3 27.3 3.9 7.7

Stamlo Beta Cardiac 4.1 3.9 5.1 4.1 0.0

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 18: Contribution of therapies to domestic sales (MAT Feb’17)

Gastro Intestinal, 21%

Cardiac, 14%

Anti-Neoplastics,

14%Respiratory,

9%

Anti-Infectives, 7%

Other, 35%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 19: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Gastro Intestinal 42.5 46.1 -7.8 41.7 1.9

Cardiac 28.6 31.7 -9.8 28.7 -0.3

Anti-Neoplastics 27.4 22.7 20.7 27.5 -0.4

Respiratory 20.5 20.1 2.0 20.7 -1.0

Anti-Infectives 15.4 16.6 -7.2 15.7 -1.9

Anti Diabetic 13.8 13.8 0.0 14.6 -5.5

Pain 12.6 13.9 -9.4 13.7 -8.0

Derma 11.6 15.2 -23.7 12.5 -7.2

Urology 7.3 8.3 -12.0 7.7 -5.2

Neuro 7.1 8.1 -12.3 7.6 -6.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 1284, 51.6%

Chronic, 695, 27.9%

Sub-Chronic,

508, 20.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb17)

27%

16%

10%13%

34%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 9: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 9

Lupin

Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Lupin

Source: NSE, ICICIdirect.com Research

Exhibit 20: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

18.4 20

.8

10.1 11

.8

4.6

11.2 12

.5

19.7 21

.2

17.5

5.5

8.6

5.4

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 21: Market share in Indian formulations market

3.3 3.33.3 3.3

3.1 3.2 3.2

3.5

3.6

3.3 3.3 3.33.3

3.0

3.2

3.4

3.6

3.8

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 22: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Gluconorm-G Anti Diabetic 14.7 12.0 22.5 15.3 -3.9

Budamate Respiratory 8.3 7.4 12.2 9.2 -9.8

Tonact Cardiac 7.0 7.8 -10.3 7.5 -6.7

Rablet-D Gastro Intestinal 5.6 4.7 19.1 5.5 1.8

Esiflo Respiratory 4.4 4.0 10.0 5.0 -12.0

Rablet Gastro Intestinal 4.1 3.8 7.9 4.0 2.5

Ivabrad Cardiac 4.0 3.4 17.6 4.2 -4.8

Telekast-L Respiratory 3.8 3.5 8.6 4.4 -13.6

Novastat Cardiac 3.7 2.9 27.6 3.6 2.8

Clopitab-A Cardiac 3.4 3.2 6.3 3.6 -5.6

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 23: Contribution of therapies to domestic sales (MAT Feb’17)

Cardiac, 24%

Anti-Infectives, 19%

Anti Diabetic, 13%Respiratory,

13%

Gastro Intestinal, 8%

Other, 23%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 24: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 71.1 70.1 1.4 75.4 -5.7

Anti-Infectives 49.9 57.9 -13.8 50.2 -0.6

Anti Diabetic 42.3 31.6 33.9 43.2 -2.1

Respiratory 40.7 36.4 11.8 43.2 -5.8

Gastro Intestinal 23.6 20.8 13.5 23.9 -1.3

Neuro 14.3 14.2 0.7 15.0 -4.7

Vitamins 13.0 13.2 -1.5 13.4 -3.0

Pain 11.9 11.6 2.6 12.5 -4.8

Gynaecological 11.8 10.1 16.8 11.6 1.7

Ophthal 2.4 1.9 26.3 2.4 0.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 1180, 32.4%

Chronic, 1805, 49.6%

Sub-Chronic,

656, 18.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

25%

14%11%

16%

34%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 10: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 10

Cadila Healthcare

Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Cadila Healthcare

Source: NSE, ICICIdirect.com Research Exhibit 25: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7

10.1

7.1

15.8

11.5

7.4 10

.1

5.6 7.

1

10.3

15.2

15.6

18.1

12.3

17.3

10.6

02468

101214161820

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 26: Market share in Indian formulations market

4.3 4.4 4.3 4.24.1 4.0 4.0

4.24.4

4.34.4

4.54.4

3.0

3.4

3.8

4.2

4.6

5.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 27: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Skinlite Derma 17.8 17.7 0.6 17.8 0.0

Deriphyllin Respiratory 10.5 10.0 5.0 11.6 -9.5

Atorva Cardiac 9.9 11.5 -13.9 9.4 5.3

Mifegest Kit Gynaecological 9.6 11.6 -17.2 8.8 9.1

Pantodac Gastro Intestinal 8.9 8.7 2.3 8.8 1.1

Thrombophob Pain 6.2 4.9 26.5 5.5 12.7

Formonide Respiratory 6.1 5.3 15.1 6.2 -1.6

Amicin Anti-Infectives 6.1 3.6 69.4 4.9 24.5

Amlodac Cardiac 5.6 5.6 0.0 5.2 7.7

Deca Durabolin Others 5.6 0.0 NA 3.4 64.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 28: Contribution of therapies to domestic sales (MAT Feb’17)

Cardiac, 15% Anti-Infectives,

15%

Gastro Intestinal, 12%

Respiratory, 10%

Gynaecological, 9%

Other, 39%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 29: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 59.7 55.8 7.0 60.5 -1.3

Anti-Infectives 54.0 49.9 8.2 57.8 -6.6

Gastro Intestinal 46.1 40.9 12.7 44.8 2.9

Respiratory 42.5 40.0 6.3 46.3 -8.2

Gynaecological 40.1 40.7 -1.5 37.9 5.8

Pain 36.3 31.6 14.9 36.8 -1.4

Derma 31.3 28.1 11.4 31.0 1.0

Anti-Neoplastics 20.4 13.7 48.9 33.4 -38.9

Vitamins 17.6 14.2 23.9 18.3 -3.8

Others 11.8 5.4 118.5 10.4 13.5

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 2286, 49.1%

Chronic, 1497, 32.1%

Sub-Chronic,

875, 18.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

21%

12%

9%12%

46%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 11: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 11

GlaxoSmithKline

Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma GSK Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 30: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

3.1

-6.2

-8.6 -0.7

-6.7

3.6

4.3

-3.3

-10.

5

-0.4

-5.4

5.0

6.3

-15

-10

-5

0

5

10

15

20

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market GSK Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 31: Market share in Indian formulations market

3.2 3.1 3.1 3.0 2.9 3.0 3.0 2.9 2.9 3.0 3.03.2 3.2

0.6

1.1

1.6

2.1

2.6

3.1

3.6

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

GSK Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 32: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Augmentin Anti-Infectives 25.4 27.8 -8.6 25.4 0.0

Synflorix Vaccines 24.9 15.8 57.6 22.1 12.7

Betnovate N Derma 15.0 12.8 17.2 15.1 -0.7

Zinetac Gastro Intestinal 13.9 13.4 3.7 18.3 -24.0

Betnovate C Derma 13.6 14.1 -3.5 15.4 -11.7

Calpol Pain 12.7 13.8 -8.0 12.7 0.0

Eltroxin Hormones 12.2 11.5 6.1 12.7 -3.9

Ceftum Anti-Infectives 9.6 10.1 -5.0 10.6 -9.4

Rotarix Vaccines 8.4 8.7 -3.4 8.4 0.0

Havrix (Pead.) Vaccines 8.1 4.4 84.1 7.4 9.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 33: Contribution of therapies to domestic sales (MAT Feb’17)

Anti-Infectives, 22%

Derma, 17%

Vaccines, 18%Respiratory, 8%

Vitamins , 8%

Other, 27%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 34: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Anti-Infectives 59.3 62.6 -5.3 61.1 -2.9

Derma 57.7 47.6 21.2 57.8 -0.2

Vaccines 56.3 46.5 21.1 53.9 4.5

Respiratory 21.7 22.8 -4.8 23.2 -6.5

Vitamins 21.2 17.7 19.8 21.4 -0.9

Hormones 20.7 20.7 0.0 21.8 -5.0

Pain 20.6 23.1 -10.8 21.2 -2.8

Gastro Intestinal 16.2 15.5 4.5 20.5 -21.0

Cardiac 4.4 4.4 0.0 4.5 -2.2

Gynaecological 1.6 3.0 -46.7 1.8 -11.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 2192, 65.8%

Chronic, 423, 12.7%

Sub-Chronic,

717, 21.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

50%

17%

9%

11%

13%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 12: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 12

Wockhardt

Stock Performance

050

100150200250300350400

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Wockhardt

Source: NSE, ICICIdirect.com Research Exhibit 35: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7

10.1

7.1

4.7

2.9 4.

8

9.3

1.0

1.8

10.7

4.1

2.4

17.9 18

.8

13.5

11.6

02468

101214161820

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 36: Market share in Indian formulations market

1.3 1.3 1.3 1.2 1.2 1.2 1.2 1.3 1.3 1.4 1.4 1.4 1.4

0.00.20.40.60.81.01.21.41.6

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 37: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Spasmo Proxyvon PluGastro Intestinal 38.3 24.8 54.4 37.9 1.1

Practin Vitamins 6.5 6.0 8.3 7.5 -13.3

Tryptomer Neuro 5.4 5.1 5.9 3.9 38.5

Bro Zedex Respiratory 4.2 5.0 -16.0 4.6 -8.7

Methycobal Vitamins 4.0 3.6 11.1 3.9 2.6

Wepox Blood Related 3.6 0.5 620.0 3.1 16.1

Butaproxyvon Pain 3.4 2.2 54.5 3.0 13.3

Biovac A Vaccines 3.2 2.5 28.0 3.4 -5.9

Zedex Respiratory 3.0 3.5 -14.3 4.0 -25.0

Biovac V Vaccines 3.0 3.5 -14.3 3.3 -9.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 38: Contribution of therapies to domestic sales (MAT Feb’17)

Gastro Intestinal, 27%

Vitamins , 15%Respiratory,

12%Neuro , 8%

Anti Diabetic, 7%

Other, 31%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 39: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Gastro Intestinal 40.1 26.1 53.6 39.7 1.0

Vitamins 15.7 15.5 1.3 17.1 -8.2

Respiratory 15.0 16.4 -8.5 16.6 -9.6

Neuro 10.0 9.0 11.1 8.5 17.6

Anti Diabetic 7.6 8.0 -5.0 8.0 -5.0

Pain 7.5 7.9 -5.1 7.2 4.2

Vaccines 7.1 6.1 16.4 7.6 -6.6

Anti-Infectives 7.0 8.7 -19.5 6.0 16.7

Derma 6.4 7.4 -13.5 7.0 -8.6

Blood Related 3.8 0.8 375.0 3.2 18.8

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 987,

68.8%

Chronic, 292,

20.4%

Sub-Chronic,

155, 10.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

56%

14%

8%

8%

14%

Top 10 11 to 20 21 to 30 31 to 50 Others

Page 13: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 13

Glenmark Pharmaceuticals

Stock Performance

6080

100120140160180200

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Glenmark

Source: NSE, ICICIdirect.com Research

Exhibit 40: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

19.8

14.9

8.6

8.7

7.6 8.6

21.0

11.9

7.8

19.7

6.0

15.8

13.5

-4

4

12

20

28

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Glenmark Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 41: Market share in Indian formulations market

2.4 2.42.3

2.2

2.3 2.3

2.42.3

2.42.5 2.5

2.62.5

2.1

2.2

2.3

2.4

2.5

2.6

2.7

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Glenmark Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 42: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Telma H Cardiac 14.2 11.8 20.3 15.7 -9.6

Telma Cardiac 13.6 16.5 -17.6 15.0 -9.3

Ascoril Plus Respiratory 11.4 9.5 20.0 11.7 -2.6

Telma Am Cardiac 7.6 6.5 16.9 7.7 -1.3

Candid-B Derma 6.6 6.9 -4.3 8.6 -23.3

Candid Derma 6.2 5.6 10.7 6.7 -7.5

Ascoril Ls Respiratory 5.6 5.1 9.8 5.7 -1.8

Zitamet Plus Anti Diabetic 4.0 2.7 48.1 4.1 -2.4

Onabet Derma 3.8 3.3 15.2 3.7 2.7

Canditral Anti-Infectives 3.6 2.5 44.0 3.2 12.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 43: Contribution of therapies to domestic sales (MAT Feb’17)

Derma, 28%

Cardiac, 22%Respiratory, 16%

Anti-Infectives, 14%

Anti Diabetic, 7%

Other, 13%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 44: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Derma 59.2 54.8 8.0 64.1 -7.6

Cardiac 50.2 47.4 5.9 54.0 -7.0

Respiratory 43.6 35.6 22.5 42.2 3.3

Anti-Infectives 31.8 25.4 25.2 29.0 9.7

Anti Diabetic 13.9 14.3 -2.8 14.8 -6.1

Gastro Intestinal 7.5 4.6 63.0 7.7 -2.6

Gynaecological 6.1 4.7 29.8 6.0 1.7

Vitamins 4.4 5.1 -13.7 4.7 -6.4

Pain 3.7 4.0 -7.5 3.6 2.8

Ophthal 2.6 2.4 8.3 2.8 -7.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 1092, 41.6%

Chronic, 918, 35.0%

Sub-Chronic,

616, 23.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

35%

12%10%

13%

30%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 14: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 14

Torrent Pharmaceuticals

Stock Performance

4080

120160200

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Torrent Pharma

Source: NSE, ICICIdirect.com Research Exhibit 45: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.113

.6

11.4

4.2

6.3

6.6 10

.2

17.0

21.2

14.6

21.9

14.5 17

.0

9.9

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Torrent Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 46: Market share in Indian formulations market

2.3 2.3 2.3 2.32.4

2.32.2 2.2 2.2

2.3 2.3 2.3 2.3

1.5

1.71.9

2.1

2.32.5

2.72.9

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Torrent Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 47: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Shelcal Vitamins 13.9 13.5 3.0 14.3 -2.8

Chymoral Forte Pain 8.6 6.8 26.5 8.7 -1.1

Nikoran Cardiac 7.7 7.9 -2.5 8.0 -3.8

Azulix-Mf Anti Diabetic 7.1 4.5 57.8 7.0 1.4

Nebicard Cardiac 6.7 5.1 31.4 6.9 -2.9

Dilzem Cardiac 6.3 6.0 5.0 6.3 0.0

Nexpro Rd Gastro Intestinal 5.7 5.2 9.6 5.8 -1.7

Nexpro Gastro Intestinal 4.8 4.4 9.1 5.0 -4.0

Rozucor Cardiac 3.9 3.4 14.7 4.0 -2.5

Deplatt Cv Cardiac 3.5 3.4 2.9 3.5 0.0

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 48: Contribution of therapies to domestic sales (MAT Feb’17)

Cardiac, 30%

Neuro , 17%Gastro Intestinal, 15%

Vitamins , 14%

Anti Diabetic, 7%

Other, 17%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 49: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 63.9 59.8 6.9 65.0 -1.7

Neuro 37.3 32.9 13.4 36.6 1.9

Gastro Intestinal 31.5 29.6 6.4 32.1 -1.9

Vitamins 28.1 27.6 1.8 28.7 -2.1

Anti Diabetic 16.0 11.9 34.5 16.0 0.0

Pain 14.9 12.6 18.3 14.9 0.0

Derma 7.0 6.2 12.9 7.1 -1.4

Anti-Infectives 6.5 8.1 -19.8 6.9 -5.8

Gynaecological 2.3 2.7 -14.8 2.3 0.0

Respiratory 0.9 0.6 50.0 0.9 0.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 579, 22.9%

Chronic, 1353, 53.4%

Sub-Chronic,

602, 23.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

32%

14%9%

12%

33%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 15: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 15

Ipca Laboratories

Stock Performance

5075

100125150

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Ipca

Source: NSE, ICICIdirect.com Research Exhibit 50: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

11.1

2.2

3.0

3.0

4.1

17.9

28.8

8.7

4.9

8.8

2.9

2.0

3.0

0

5

10

15

20

25

30

35

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Ipca Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 51: Market share in Indian formulations market

1.2 1.1 1.2 1.2 1.21.3 1.4 1.4 1.3

1.2 1.1 1.1 1.1

0.0

0.5

1.0

1.5

2.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Ipca Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 52: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Zerodol Sp Pain 8.7 8.4 3.6 7.7 13.0

Hcqs Anti Malarials 6.3 5.3 18.9 5.1 23.5

Zerodol P Pain 5.1 5.7 -10.5 6.3 -19.0

Glycinorm M Anti Diabetic 3.2 2.9 10.3 3.3 -3.0

Folitrax Anti-Neoplastics 2.9 2.7 7.4 2.8 3.6

Zerodol Th Pain 2.5 1.9 31.6 2.3 8.7

Larinate Anti Malarials 2.4 2.0 20.0 1.7 41.2

Zerodol Pain 2.2 2.0 10.0 2.0 10.0

Ctd Cardiac 2.1 2.1 0.0 1.8 16.7

Saaz Gastro Intestinal 2.0 1.5 33.3 2.1 -4.8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 53: Contribution of therapies to domestic sales (MAT Feb’17)

Pain , 26%

Cardiac, 16%Anti Malarials,

19%

Gastro Intestinal, 8%

Anti-Infectives, 6%

Other, 25%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 54: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Pain 27.8 26.8 3.7 27.2 2.2

Cardiac 18.2 18.3 -0.5 17.8 2.2

Anti Malarials 13.8 15.3 -9.8 11.1 24.3

Gastro Intestinal 8.0 7.7 3.9 7.5 6.7

Anti-Infectives 6.7 6.3 6.3 6.4 4.7

Anti Diabetic 5.7 5.5 3.6 5.8 -1.7

Respiratory 4.7 5.3 -11.3 4.8 -2.1

Anti-Neoplastics 4.6 4.5 2.2 4.8 -4.2

Neuro 4.6 3.4 35.3 5.2 -11.5

Derma 4.4 3.2 37.5 4.5 -2.2

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 889, 65.6%

Chronic, 372, 27.4%

Sub-Chronic, 95, 7.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

37%

16%11%

13%

23%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 16: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 16

Biocon

Stock Performance

60100140180220

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Biocon

Source: NSE, ICICIdirect.com Research

Exhibit 55: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

12.0

11.1

7.4

7.4

3.4

3.6

10.7

11.1

3.4

26.9

10.7

10.3

3.6

0

5

10

15

20

25

30

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 56: Market share in Indian formulations market

0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.3

0.0

0.2

0.4

0.6

0.8

1.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 57: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Insugen Anti Diabetic 8.2 6.9 18.8 8.4 -2.4

Basalog Anti Diabetic 5.2 4.7 10.6 5.2 0.0

Erypro Blood Related 1.9 1.4 35.7 3.0 -36.7

Canmab Anti-Neoplastics 1.7 1.6 6.3 3.0 -43.3

Insugen R Anti Diabetic 1.7 1.4 21.4 1.8 -5.6

Blisto Mf Anti Diabetic 1.2 1.4 -14.3 1.0 20.0

Abraxane Anti-Neoplastics 0.0 1.1 -100.0 0.0 NA

Biomab Egfr Anti-Neoplastics 1.3 1.4 -7.1 2.4 -45.8

Psorid Anti-Neoplastics 0.7 0.6 16.7 0.8 -12.5

Insugen N Anti Diabetic 0.6 0.6 0.0 0.6 0.0

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 58: Contribution of therapies to domestic sales (MAT Feb’17)

Anti Diabetic,

57%Anti-

Neoplastics, 22%

Blood Related, 10%

Cardiac, 5%

Anti-Infectives, 2% Other , 4%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 59: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Anti Diabetic 18.1 16.2 11.7 18.0 0.6

Anti-Neoplastics 5.7 6.8 -16.2 7.8 -26.9

Blood Related 2.0 1.4 42.9 3.1 -35.5

Cardiac 1.3 1.4 -7.1 1.2 8.3

Anti-Infectives 0.9 0.7 28.6 0.7 28.6

Derma 0.8 0.8 0.0 0.8 0.0

Others 0.2 0.2 0.0 0.3 -33.3

Gastro Intestinal 0.1 0.2 -50.0 0.1 0.0

Vitamins 0.1 0.2 -50.0 0.1 0.0

Pain 0.1 0.0 NA 0.0 NA

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 74, 20.5%

Chronic, 259, 71.3%

Sub-Chronic, 30, 8.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

79%

10%

5%5%

1%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 17: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 17

Pfizer

Stock Performance

4080

120160200

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Pfizer

Source: NSE, ICICIdirect.com Research Exhibit 60: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

5.0

3.6

2.4

7.6

-0.9

2.8 6.

9

2.4

0.4 6.

4

-3.3

-1.7

0.9

-5

0

5

10

15

20

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 61: Market share in Indian formulations market

2.8 2.8 2.9 2.82.7 2.7 2.6 2.6 2.7 2.6 2.6 2.5 2.6

2.0

2.4

2.8

3.2

3.6

4.0

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 62: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Becosules Vitamins 16.9 16.0 5.6 15.8 7.0

Minipress Xl Cardiac 11.2 8.8 27.3 11.3 -0.9

Gelusil Mps Gastro Intestinal 11.1 11.7 -5.1 12.0 -7.5

Dolonex Pain 11.1 10.7 3.7 10.6 4.7

Prevenar 13 Vaccines 11.0 3.2 243.8 11.3 -2.7

Magnex Anti-Infectives 11.0 11.5 -4.3 12.8 -14.1

Mucaine Gastro Intestinal 9.0 8.7 3.4 9.0 0.0

Wysolone Hormones 7.9 6.8 16.2 10.2 -22.5

Corex Dx Respiratory 7.5 5.8 29.3 9.1 -17.6

Ovral L Gynaecological 6.6 4.9 34.7 5.8 13.8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 63: Contribution of therapies to domestic sales (MAT Feb’17)

Anti-Infectives,

14%

Gastro Intestinal, 10%

Gynaecological, 9%

Vitamins , 10%

Hormones, 9%

Other, 48%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 64: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Anti-Infectives 34.0 40.3 -15.6 33.4 1.8

Gastro Intestinal 24.5 25.6 -4.3 25.2 -2.8

Gynaecological 22.0 18.7 17.6 22.0 0.0

Vitamins 21.1 20.6 2.4 20.1 5.0

Hormones 20.7 20.0 3.5 23.2 -10.8

Neuro 18.0 18.0 0.0 16.3 10.4

Cardiac 17.5 14.5 20.7 16.8 4.2

Respiratory 17.3 31.7 -45.4 21.2 -18.4

Vaccines 15.4 6.6 133.3 15.9 -3.1

Pain 14.9 14.4 3.5 14.6 2.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 1890, 64.3%

Chronic, 472, 16.1%

Sub-Chronic,

579, 19.7%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

48%

20%

11%

10%

11%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 18: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 18

Novartis

Stock Performance

40

90

140

190

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Novartis India

Source: NSE, ICICIdirect.com Research

Exhibit 65: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

23.9

21.7

18.2

14.5

4.9

4.5

5.5

14.1

4.8

0

5

10

15

20

25

30

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Novartis India

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 66: Market share in Indian formulations market

1.0 1.0 1.0 1.0 1.0 0.9 0.9 1.0 1.01.0

1.0 0.91.0

0.0

0.2

0.4

0.6

0.8

1.0

1.2

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Novartis India

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 67: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Galvus Met Anti Diabetic 26.4 23.7 11.4 25.7 2.7

Voveran Pain 20.3 15.7 29.3 16.6 22.3

Galvus Anti Diabetic 9.4 8.9 5.6 9.7 -3.1

Tegrital Neuro 4.7 5.1 -7.8 4.8 -2.1

Voveran Pain 2.9 2.8 3.6 3.0 -3.3

Regestrone Gynaecological 2.5 2.6 -3.8 2.4 4.2

Methergin Gynaecological 2.5 2.3 8.7 2.4 4.2

Syntocinon Gynaecological 2.3 2.3 0.0 2.2 4.5

Citro Macalvit Vitamins 1.7 1.5 13.3 1.5 13.3

Macalvit Vitamins 1.6 1.8 -11.1 1.5 6.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 68: Contribution of therapies to domestic sales (MAT Feb’17)

Anti Diabetic, 42%

Pain , 26%

Vitamins , 10%

Gynaecological, 8%

Neuro , 5%Other, 9%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 69: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Anti Diabetic 36.2 33.1 9.4 35.9 0.8

Pain 24.1 20.0 20.5 20.5 17.6

Vitamins 8.4 8.8 -4.5 6.7 25.4

Gynaecological 7.4 7.4 0.0 7.0 5.7

Neuro 4.7 5.2 -9.6 4.8 -2.1

Anti-Infectives 2.2 4.2 -47.6 2.2 0.0

Respiratory 1.5 2.2 -31.8 1.7 -11.8

Cardiac 0.7 0.9 -22.2 0.6 16.7

Anti-Neoplastics 0.5 0.2 150.0 0.5 0.0

Hormones 0.4 0.1 300.0 0.2 100.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 405, 37.8%

Chronic, 517, 48.4%

Sub-Chronic,

148, 13.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

83%

9%4%

3%1%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 19: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 19

Unichem Laboratories

Stock Performance

70100130160

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Unichem Labs

Source: NSE, ICICIdirect.com Research

Exhibit 70: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

10.6

2.9

8.5 11

.1

12.5

18.3

27.1

20.8 16

.2

21.7

10.7

7.9 8.2

0

5

10

15

20

25

30

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Unichem Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 71: Market share in Indian formulations market

0.90.9 0.9

0.90.9

0.9 0.9

0.9

0.90.9

0.9 0.9

0.9

0.80.80.90.90.90.90.90.90.90.90.90.9

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Unichem Lab Source: AIOCD data base, ICICIdirect.com Research

Exhibit 72: Top 10 brands performance (| crore)

Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Losar H Cardiac 8.7 7.1 22.5 8.9 -2.2

Losar Cardiac 6.0 5.6 7.1 6.7 -10.4

Ampoxin Anti-Infectives 5.3 5.5 -3.6 6.1 -13.1

Unienzyme Gastro Intestinal 4.8 3.8 26.3 3.7 29.7

Vizylac Gastro Intestinal 2.4 2.3 4.3 2.5 -4.0

Trika Neuro 2.1 2.0 5.0 2.2 -4.5

Serta Neuro 1.8 1.9 -5.3 1.8 0.0

Arkamin Cardiac 1.8 1.5 20.0 1.7 5.9

Unistar (Unichem) Cardiac 1.7 1.5 13.3 1.8 -5.6

Telsar Cardiac 1.4 1.6 -12.5 1.5 -6.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 73: Contribution of therapies to domestic sales (MAT Feb’17)

Cardiac, 42%

Anti-Infectives, 16%

Neuro , 14%

Gastro Intestinal, 12%

Anti Diabetic, 5%

Other, 11%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 74: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 34.3 31.9 7.5 36.6 -6.3

Anti-Infectives 11.8 12.2 -3.3 12.9 -8.5

Neuro 11.5 10.3 11.7 11.7 -1.7

Gastro Intestinal 8.6 7.3 17.8 7.5 14.7

Anti Diabetic 4.6 3.1 48.4 4.7 -2.1

Pain 2.9 2.9 0.0 3.0 -3.3

Vitamins 1.9 1.5 26.7 1.9 0.0

Respiratory 1.7 1.7 0.0 1.8 -5.6

Derma 1.7 1.7 0.0 1.8 -5.6

Gynaecological 0.2 0.5 -60.0 0.2 0.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 340,

34.5%

Chronic, 585,

59.4%

Sub-Chronic, 60, 6.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

32%

14%9%

12%

33%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 20: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 20

Indoco Remedies

Stock Performance

6080

100120140

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Indoco

Source: NSE, ICICIdirect.com Research

Exhibit 75: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

5.5 1.

9

0.0 5.

7 11.3

29.3

34.5

18.0

6.3

8.5

5.0

17.5

15.5

0

5

10

15

20

25

30

35

40

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 76: Market share in Indian formulations market

0.7 0.70.6 0.6 0.7

0.8 0.80.7 0.7 0.7 0.7

0.7 0.7

0.50.60.60.70.70.80.80.90.91.01.01.11.1

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 77: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Febrex Plus Respiratory 6.9 5.6 23.2 7.6 -9.2

Oxipod Anti-Infectives 4.0 3.5 14.3 3.6 11.1

Cyclopam Gastro Intestinal 3.9 3.1 25.8 3.8 2.6

Cital Urology 3.3 2.8 17.9 2.6 26.9

Sensodent-K Stomatologicals 3.0 2.7 11.1 3.1 -3.2

Atm Anti-Infectives 2.6 2.4 8.3 2.7 -3.7

Cyclopam Gastro Intestinal 2.1 1.6 31.3 2.0 5.0

Karvol Plus Respiratory 2.0 2.2 -9.1 2.8 -28.6

Cloben G Derma 1.8 1.6 12.5 1.8 0.0

Sensodent-Kf Stomatologicals 1.5 1.6 -6.3 1.7 -11.8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 78: Contribution of therapies to domestic sales (MAT Feb’17) Respiratory,

19%

Anti-Infectives, 18%

Stomatologicals, 16%

Gastro Intestinal, 13%

Vitamins , 8%

Other, 26%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 79: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Respiratory 12.8 11.3 13.3 14.3 -10.5

Anti-Infectives 11.9 10.7 11.2 11.5 3.5

Stomatologicals 9.6 9.0 6.7 10.1 -5.0

Gastro Intestinal 9.0 7.4 21.6 8.9 1.1

Vitamins 5.7 4.0 42.5 5.6 1.8

Ophthal 3.7 2.9 27.6 3.2 15.6

Urology 3.6 3.1 16.1 3.0 20.0

Pain 2.7 2.5 8.0 2.7 0.0

Anti Diabetic 2.5 1.8 38.9 2.3 8.7

Derma 2.5 2.3 8.7 2.6 -3.8

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 641,

82.3%

Chronic, 44, 5.6%

Sub-Chronic,

94, 12.1%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

48%

15%

9%

10%

18%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 21: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 21

Ajanta Pharmaceuticals

Stock Performance

4090

140190240290

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Ajanta

Source: NSE, ICICIdirect.com Research

Exhibit 80: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8

11.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

15.2

13.6

20.0

18.8

18.8

14.0 15

.7

7.5

11.8 13

.5

11.1

19.2

9.4

0

5

10

15

20

25

Feb-

16

Mar

-16

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov-

16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 81: Market share in Indian formulations market

0.6 0.6 0.6 0.7 0.70.6 0.6 0.6 0.6 0.6 0.7 0.70.6

0.00.10.20.30.40.50.60.70.8

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 82: Top 10 brands performance (| crore) Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Met Xl Cardiac 6.8 5.6 21.4 7.6 -10.5

Atorfit Cv Cardiac 4.0 3.9 2.6 4.5 -11.1

Melacare Derma 3.7 4.8 -22.9 4.6 -19.6

Feburic Pain 1.8 1.6 12.5 1.8 0.0

Rosufit Cv Cardiac 1.6 1.4 14.3 2.1 -23.8

Met Xl Am Cardiac 1.5 1.4 7.1 1.7 -11.8

Soft Drops Ophthal 1.5 1.3 15.4 1.5 0.0

Cinod Cardiac 1.3 1.0 30.0 1.4 -7.1

Rosutor Gold Cardiac 1.3 1.1 18.2 1.6 -18.8

Maxmoist Ophthal 0.8 0.6 33.3 0.7 14.3

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 83: Contribution of therapies to domestic sales (MAT Feb’17)

Cardiac, 37%

Ophthal , 23%Derma, 19%

Pain , 5%

Vitamins , 5%

Others, 11%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 84: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)

Cardiac 21.7 18.5 17.3 24.4 -11.1

Ophthal 14.2 12.5 13.6 13.7 3.6

Derma 10.2 11.4 -10.5 11.2 -8.9

Pain 2.7 2.6 3.8 2.8 -3.6

Vitamins 2.5 2.9 -13.8 2.6 -3.8

Neuro 1.2 1.1 9.1 1.3 -7.7

Anti Diabetic 1.2 0.6 100.0 1.3 -7.7

Anti-Infectives 1.1 0.9 22.2 1.5 -26.7

Gastro Intestinal 1.0 1.3 -23.1 1.2 -16.7

Others 0.5 0.0 NA 0.4 25.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 264, 38.5%

Chronic, 347, 50.5%

Sub-Chronic,

75, 11.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

43%

12%9%

12%

24%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 22: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 22

Alembic Pharmaceuticals

Stock Performance

406080

100120140160180200

Feb-16 Apr-16 Jun-16 Aug-16 Oct-16 Dec-16 Feb-17

CNX Pharma Alembic Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 85: Company growth vis-à-vis Indian pharma market growth

13.5

8.1

5.5

9.7

7.8 11

.0

17.4

13.5

9.1

15.7

7.7 10

.1

7.1

13.6

7.9

4.7

12.1

11.9

18.0 20

.3

11.3

6.4

4.2

-2.4

-1.7 -2

.6

-5

0

5

10

15

20

25Fe

b-16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Indian Pharma Market Alembic

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 86: Market share in Indian formulations market

1.4

1.3

1.3 1.31.3

1.41.4

1.4 1.4

1.3 1.31.3

1.3

1.2

1.2

1.3

1.3

1.4

1.4

1.5

Feb-

16

Mar

-16

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

(%)

Alembic

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 87: Top 10 brands performance (| crore)

Brand Therapy Feb' 17 Feb' 16 Var. (%) Jan' 17 Var. (%)

Azithral Anti-Infectives 11.5 12.1 -5.0 11.5 0.0

Althrocin Anti-Infectives 5.5 5.5 0.0 6.3 -12.7

Wikoryl Respiratory 4.8 4.7 2.1 5.3 -9.4

Gestofit Gynaecological 4.4 4.6 -4.3 4.7 -6.4

Roxid Anti-Infectives 3.6 4.9 -26.5 4.2 -14.3

Rekool D Gastro Intestinal 2.4 2.7 -11.1 2.5 -4.0

Ulgel Gastro Intestinal 2.1 2.7 -22.2 2.2 -4.5

Richar Gynaecological 1.9 2.0 -5.0 2.2 -13.6

Glisen Mf Anti Diabetic 1.8 2.0 -10.0 1.9 -5.3

Rekool Gastro Intestinal 1.7 2.1 -19.0 1.9 -10.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 88: Contribution of therapies to domestic sales (MAT Feb’17)

Anti-Infectives, 22%

Cardiac, 14%Respiratory,

13%Gastro Intestinal, 13%

Gynaecological, 12%

Other, 26%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 89: Therapy wise performance (| crore)

Therapy Feb' 17 Feb' 16 YoY (%) Jan' 17 MoM (%)Anti-Infectives 24.7 27.1 -8.9 26.0 -5.0Cardiac 17.3 16.5 4.8 17.9 -3.4Respiratory 15.5 17.0 -8.8 17.3 -10.4Gastro Intestinal 13.5 15.3 -11.8 14.2 -4.9Gynaecological 12.9 12.3 4.9 13.7 -5.8Anti Diabetic 8.6 7.4 16.2 9.0 -4.4Vitamins 8.5 8.9 -4.5 8.7 -2.3Pain 3.5 4.4 -20.5 3.8 -7.9Urology 3.2 2.3 39.1 3.0 6.7Derma 1.8 2.2 -18.2 1.8 0.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Feb’17)

Acute, 836,

57.0%

Chronic 231.46, 18.8%

Sub-Chronic 214.35, 17.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Feb’17)

43%

12%9%

12%

24%

Top 10 11 to 20 21 to 30 31 to 50 Others

Page 23: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 23

Exhibit 90: One year forward P/E of CNX Pharma vs. Sensex

05

1015202530354045

Mar

-07

Sep-

07

Mar

-08

Sep-

08

Mar

-09

Sep-

09

Mar

-10

Sep-

10

Mar

-11

Sep-

11

Mar

-12

Sep-

12

Mar

-13

Sep-

13

Mar

-14

Sep-

14

Mar

-15

Sep-

15

Mar

-16

Sep-

16

Mar

-17

x

CNX Pharma Sensex

21% Premium

[

Source: Company, ICICIdirect.com Research

ICICIdirect.com coverage universe (Healthcare) Company I-Direct CMP TP Rating M Cap

Code (|) (|) (| Cr) FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E

Ajanta Pharma AJAPHA 1764 1,960 Buy 15524.1 45.4 59.7 66.3 75.3 38.8 29.6 26.6 23.4 42.9 39.2 34.9 31.7 34.2 33.1 28.4 25.6

Alembic Pharma ALEMPHA 617 615 Hold 11622.0 38.2 22.0 24.5 30.6 16.2 28.1 25.2 20.1 51.5 26.0 23.1 24.8 44.9 21.9 20.8 21.9

Apollo Hospitals APOHOS 1225 1,440 Buy 17038.0 22.2 19.9 32.6 49.1 55.2 61.5 37.6 25.0 8.2 7.5 10.5 14.6 8.9 7.5 11.1 14.7

Aurobindo Pharma AURPHA 687 965 Buy 40183.6 33.9 40.1 40.7 50.7 20.2 17.1 16.9 13.5 23.3 24.3 21.3 23.0 28.1 25.3 20.7 20.8

Biocon BIOCON 1123 1,120 Buy 22456.0 23.1 32.6 34.4 44.2 48.5 34.4 32.6 25.4 9.1 13.0 13.7 16.5 11.4 14.4 13.7 15.4

Cadila Healthcare CADHEA 443 425 Hold 45382.5 15.0 11.2 16.6 21.1 29.6 39.5 26.7 21.0 26.7 14.4 19.9 22.9 28.6 18.5 22.8 23.8Cipla CIPLA 602 575 Hold 48429.2 18.5 17.8 24.7 31.9 32.5 33.7 24.3 18.9 12.0 10.9 14.0 16.6 12.5 10.9 13.4 15.0

Divi's Lab DIVLAB 776 925 Buy 20603.0 41.8 44.6 51.8 57.9 18.6 17.4 15.0 13.4 30.7 28.5 28.0 26.5 25.9 23.0 22.2 20.7

Dr Reddy's Labs DRREDD 2758 2,930 Hold 45690.8 141.4 74.5 114.5 154.3 19.5 37.0 24.1 17.9 17.3 7.0 11.5 15.1 20.6 10.0 13.6 15.8

Glenmark Pharma GLEPHA 900 1,155 Buy 25395.1 32.2 63.0 54.4 60.8 28.0 14.3 16.5 14.8 16.2 26.8 20.8 21.9 21.2 29.7 20.6 18.8

Indoco Remedies INDREM 258 315 Buy 2375.2 9.4 8.9 14.2 18.5 27.5 29.1 18.1 13.9 12.9 9.7 14.9 18.1 14.8 12.6 17.4 19.2

Ipca Laboratories IPCLAB 556 560 Hold 7016.4 10.0 15.1 24.1 31.2 55.5 36.9 23.1 17.8 5.7 9.9 12.8 14.8 5.5 7.8 11.3 13.0

Jubilant Life JUBLIF 804 810 Buy 12811.0 26.0 37.4 53.9 67.5 30.9 21.5 14.9 11.9 12.0 14.2 16.2 18.3 14.2 17.3 20.2 20.4

Lupin LUPIN 1452 1,890 Buy 65557.6 50.4 62.2 67.5 83.8 28.8 23.3 21.5 17.3 18.6 20.3 20.8 23.9 20.7 21.1 19.2 19.9

Natco Pharma NATPHA 793 870 Buy 13815.6 8.5 23.8 14.8 18.2 93.4 33.3 53.7 43.6 16.0 31.5 17.8 19.4 11.9 26.0 14.1 15.2

Sun Pharma SUNPHA 713 765 Buy 170969.2 23.4 29.9 29.9 35.3 30.4 23.8 23.8 20.2 18.6 19.1 17.3 18.0 18.0 19.2 16.6 16.8

Syngene Int. SYNINT 512 570 Hold 10230.0 11.1 15.5 16.9 20.5 51.3 36.7 33.7 27.7 13.2 17.8 18.1 20.7 21.0 23.2 20.6 20.4

Torrent Pharma TORPHA 1369 1,475 Buy 23161.5 107.8 55.7 62.2 77.6 12.7 24.6 22.0 17.6 46.7 21.0 23.8 26.5 53.8 23.0 21.5 22.3

Unichem Lab UNILAB 284 285 Hold 2577.7 12.3 13.2 17.5 23.7 23.0 21.5 16.2 12.0 13.8 14.5 16.2 18.9 11.7 11.3 13.3 15.6

RoE (%)EPS (|) PE(x) RoCE (%)

Source: Company, ICICIdirect.com Research

Page 24: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 24

RATING RATIONALE ICICIdirect.com endeavours to provide objective opinions and recommendations. ICICIdirect.com assigns ratings to its stocks according to their notional target price vs. current market price and then categorises them as Strong Buy, Buy, Add, Reduce and Sell. The performance horizon is two years unless specified and the notional target price is defined as the analysts' valuation for a stock. Sector view: Over weight compared to index Equal weight compared to index Under weight compared to index Index here refers to BSE 500

Pankaj Pandey Head – Research [email protected]

ICICIdirect.com Research Desk, ICICI Securities Limited, 1st Floor, Akruti Trade Centre, Road No. 7, MIDC, Andheri (East) Mumbai – 400 093

[email protected]

Page 25: Some USFDA respite for Sun; not yet for DRL…content.icicidirect.com/mailimages/IDirect_HealthCheck...ICICI Securities Ltd. | Retail Equity Research March 16, 2017 Monthly Update

ICICI Securities Ltd. | Retail Equity Research

Page 25

ANALYST CERTIFICATION We /I, Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance) Research Analysts, authors and the names subscribed to this report, hereby certify that all of the views expressed in this research report accurately reflect our views about the subject issuer(s) or securities. We also certify that no part of our compensation was, is, or will be directly or indirectly related to the specific recommendation(s) or view(s) in this report.

Terms & conditions and other disclosures: ICICI Securities Limited (ICICI Securities) is full-service, integrated investment banking and is, inter alia, engaged in the business of stock brokering and distribution of financial products. ICICI Securities Limited is a Sebi registered Research Analyst with Sebi Registration Number – INH000000990. ICICI Securities is a wholly-owned subsidiary of ICICI Bank which is India’s largest private sector bank and has its various subsidiaries engaged in businesses of housing finance, asset management, life insurance, general insurance, venture capital fund management, etc. (“associates”), the details in respect of which are available on www.icicibank.com. ICICI Securities is one of the leading merchant bankers/ underwriters of securities and participate in virtually all securities trading markets in India. We and our associates might have investment banking and other business relationship with a significant percentage of companies covered by our Investment Research Department. ICICI Securities generally prohibits its analysts, persons reporting to analysts and their relatives from maintaining a financial interest in the securities or derivatives of any companies that the analysts cover. The information and opinions in this report have been prepared by ICICI Securities and are subject to change without any notice. The report and information contained herein is strictly confidential and meant solely for the selected recipient and may not be altered in any way, transmitted to, copied or distributed, in part or in whole, to any other person or to the media or reproduced in any form, without prior written consent of ICICI Securities. While we would endeavour to update the information herein on a reasonable basis, ICICI Securities is under no obligation to update or keep the information current. Also, there may be regulatory, compliance or other reasons that may prevent ICICI Securities from doing so. Non-rated securities indicate that rating on a particular security has been suspended temporarily and such suspension is in compliance with applicable regulations and/or ICICI Securities policies, in circumstances where ICICI Securities might be acting in an advisory capacity to this company, or in certain other circumstances. This report is based on information obtained from public sources and sources believed to be reliable, but no independent verification has been made nor is its accuracy or completeness guaranteed. This report and information herein is solely for informational purpose and shall not be used or considered as an offer document or solicitation of offer to buy or sell or subscribe for securities or other financial instruments. Though disseminated to all the customers simultaneously, not all customers may receive this report at the same time. ICICI Securities will not treat recipients as customers by virtue of their receiving this report. Nothing in this report constitutes investment, legal, accounting and tax advice or a representation that any investment or strategy is suitable or appropriate to your specific circumstances. The securities discussed and opinions expressed in this report may not be suitable for all investors, who must make their own investment decisions, based on their own investment objectives, financial positions and needs of specific recipient. This may not be taken in substitution for the exercise of independent judgment by any recipient. The recipient should independently evaluate the investment risks. The value and return on investment may vary because of changes in interest rates, foreign exchange rates or any other reason. ICICI Securities accepts no liabilities whatsoever for any loss or damage of any kind arising out of the use of this report. Past performance is not necessarily a guide to future performance. Investors are advised to see Risk Disclosure Document to understand the risks associated before investing in the securities markets. Actual results may differ materially from those set forth in projections. Forward-looking statements are not predictions and may be subject to change without notice. ICICI Securities or its associates might have managed or co-managed public offering of securities for the subject company or might have been mandated by the subject company for any other assignment in the past twelve months. ICICI Securities or its associates might have received any compensation from the companies mentioned in the report during the period preceding twelve months from the date of this report for services in respect of managing or co-managing public offerings, corporate finance, investment banking or merchant banking, brokerage services or other advisory service in a merger or specific transaction. ICICI Securities or its associates might have received any compensation for products or services other than investment banking or merchant banking or brokerage services from the companies mentioned in the report in the past twelve months. ICICI Securities encourages independence in research report preparation and strives to minimize conflict in preparation of research report. ICICI Securities or its associates or its analysts did not receive any compensation or other benefits from the companies mentioned in the report or third party in connection with preparation of the research report. Accordingly, neither ICICI Securities nor Research Analysts and their relatives have any material conflict of interest at the time of publication of this report. It is confirmed that Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance) Research Analysts of this report have not received any compensation from the companies mentioned in the report in the preceding twelve months. Compensation of our Research Analysts is not based on any specific merchant banking, investment banking or brokerage service transactions. ICICI Securities or its subsidiaries collectively or Research Analysts or their relatives do not own 1% or more of the equity securities of the Company mentioned in the report as of the last day of the month preceding the publication of the research report. Since associates of ICICI Securities are engaged in various financial service businesses, they might have financial interests or beneficial ownership in various companies including the subject company/companies mentioned in this report. It is confirmed that Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance) Research Analysts do not serve as an officer, director or employee of the companies mentioned in the report. ICICI Securities may have issued other reports that are inconsistent with and reach different conclusion from the information presented in this report. Neither the Research Analysts nor ICICI Securities have been engaged in market making activity for the companies mentioned in the report. We submit that no material disciplinary action has been taken on ICICI Securities by any Regulatory Authority impacting Equity Research Analysis activities. This report is not directed or intended for distribution to, or use by, any person or entity who is a citizen or resident of or located in any locality, state, country or other jurisdiction, where such distribution, publication, availability or use would be contrary to law, regulation or which would subject ICICI Securities and affiliates to any registration or licensing requirement within such jurisdiction. The securities described herein may or may not be eligible for sale in all jurisdictions or to certain category of investors. Persons in whose possession this document may come are required to inform themselves of and to observe such restriction. report and information herein is solely for informational purpose and shall not be used or considered as an offer document or solicitation of offer to buy or sell or subscribe for securities or other financial instruments. Though disseminated to all the customers simultaneously, not all customers may receive this report at the same time. ICICI Securities will not treat recipients as customers by virtue of their receiving this report. Nothing in this report constitutes investment, legal, accounting and tax advice or a representation that any investment or strategy is suitable or appropriate to your specific circumstances. The securities discussed and opinions expressed in this report may not be suitable for all investors, who must make their own investment decisions, based on their own investment objectives, financial positions and needs of specific recipient. This may not be taken in substitution for the exercise of independent judgment by any recipient. The recipient should independently evaluate the investment risks. The value and return on investment may vary because of changes in interest rates, foreign exchange rates or any other reason. ICICI Securities accepts no liabilities whatsoever for any loss or damage of any kind arising out of the use of this report. Past performance is not necessarily a guide to future performance. Investors are advised to see Risk Disclosure Document to understand the risks associated before investing in the securities markets. Actual results may differ materially from those set forth in projections. Forward-looking statements are not predictions and may be subject to change without notice. ICICI Securities or its associates might have managed or co-managed public offering of securities for the subject company or might have been mandated by the subject company for any other assignment in the past twelve months. ICICI Securities or its associates might have received any compensation from the companies mentioned in the report during the period preceding twelve months from the date of this report for services in respect of managing or co-managing public offerings, corporate finance, investment banking or merchant banking, brokerage services or other advisory service in a merger or specific transaction. ICICI Securities or its associates might have received any compensation for products or services other than investment banking or merchant banking or brokerage services from the companies mentioned in the report in the past twelve months. ICICI Securities encourages independence in research report preparation and strives to minimize conflict in preparation of research report. ICICI Securities or its analysts did not receive any compensation or other benefits from the companies mentioned in the report or third party in connection with preparation of the research report. Accordingly, neither ICICI Securities nor Research Analysts have any material conflict of interest at the time of publication of this report. It is confirmed that Siddhant Khandekar CA-INTER Mitesh Shah MS (Finance), Research Analysts of this report have not received any compensation from the companies mentioned in the report in the preceding twelve months. Compensation of our Research Analysts is not based on any specific merchant banking, investment banking or brokerage service transactions.