178

1972 and 1983. The youngest was 19 years of age; eight patients were under 30; 66 patients were males and 45 were females.

Of the entire group, only three were a-

symptomatic, having an abnormality found on incidental chest x-ray. Sixty-nine pa- tients (62%) had symptoms of two months' duration or less. Heavy cigarette smoking was common. At least 88 patients (79%) were gicarette smokers. At time of diagnosis, 104 patients (93.7%) had stage III disease; four (3.6%) stage II, and three (2.7%) stage I. Fifty-one patients (45.9%) had adenocarcinoma or bronchoalveolar carci- noma. Only eight (7.2%) had squamous cell carcinoma. Median survival of all patients was six months. Thirty-seven patients (33%) were surgically explored and 24 (21.6%) were resected. The median survi- val of resected patients, whether "curative"

or "palliative", was 17.5 months. The survival pattern of these younger

patients with bronchogenic carcinoma is similar to patients of all age groups with

bronchogenic carcinoma treated at this hospital.

Lung Cancer in Women: Epidemiological, Clinical and Surgical Aspects. Sammartino,.P., Di Giorgio, A., Di Lauro, G., Caramanico, L., Almansour, M. I Clinica Chirurgica, Universit~ di Roma, Italy.

The study was carried out on a compu-. ted data base of 1802 lung cancer patients observed during the last 30 years.

131 patients were female with a M/F ratio of 12.7/1, which in the last 5 years ha~ g~'adually decreased to 5/1.

The percentage of smokers was shown to be 29% for female pts and 93% for male pts. No difference was observed in the symptoms of the two sexes. As for the histological type a clear-cut prevalence of adenocarci- nomas (38.9%) was observed in female pts as compared to the other histological types and to the male sex (17%); epidermoid car- cioma was present in 27.4% of female pts and in 52.4% in male pts. The incidence of small cell carcinoma (28.5 and 22.9 re- respectively) and of the other types (large cell or mixed carcinoma) was shown to be

overimposable in the two sexes, (5%2% and 7.7% respectively).

Resectability was shown to be overimpo- sable (45.8% and 45.9% respectively) while p stage has shown more advanced neoplasms in female pts (p stage III: F = 61.7%, M = 46.2%).

As for prognosis after resection, female pts have shown a statistically lower (12.5%) overall 5-year survival with respect to values observed in male pts (29.1%) (p<0.05).

Bronchial Carcinoid T~ors. Elhassani, N.B. Department of Thoracic Sur-°

gery, Medical College, Baghdad University, Iraq.

Ten patients with carcinoid tumors of the tracheobronchial tree are presented. These represent 2% of patients with the clinical diagnosis of primary malignant tumors of the lung seen during a recent i0 year period at the Thoracic Surgical Unit of Medical City Hospital in Baghdad. The presumptive diagnosis was made on the basis of clinical feature, roentgenographic appearance, bronchoseopic finding and established by histopathologic evi- dence in every case. Surgical management at thoracotomy included resection or tracheo- bronchoplastic procedures for all patients. This study emphasize that recurrent attacks of re- spiratory symptoms required early bronchosco- pic evaluation.

Small Cell Lung Cancer (SCLC). Liippo, K. Department of Diseases of the Chest, University of Turku, Finland.

The aim of the study was to analyse the survival and the prognostic factors. Of 402 patients, 321 (79.8%) had histologically and 81 (20.2%) cytologically verified disease. Male/female ratio was 27:1, mean age 61.4 years. The biopsies were revised and subtyped by pa- thologist according to the WHO classification (1981).

Median survival (ms) (time) was 6.2 months in the whole series. Asymptomatic patients (54) lived longer than patients with symptoms (311), ms was 10.7 and 5.8 months, respectively (p = 0.003). Patients with limited disease survived longer (ms 6.8 months) than with extensive disease (2.6 months) (p<0.001). The survival of patients with extensive disease was shorter with intermediate subtype than with oat-cell type (p<0.001). There was no significant dif- ference in survival time between different sub- types in limited disease. 116 patients received no specific therapy. Their ms, 2.3 months, was significantly shorter than that of patients after noncurable radiation (5.4 months) or operation (6.4 months). The survival was best in group subjected to radical surgery or radi- cal radiotherapy, median survival time 12.4 and 11.5 months respectively. In the multivari- ate survival analysis with Cox's proportional hazard model performance status (Karnofsky) was first of factors associated with survival.

Conclusions: This long-term analysis forms the basis for evaluation of natural history of SCLC and will give possibilities for assess- ment of the efficacy of future treatment policy.

12, MISCELLANEOUS

Pulmonary Chemodextoma Presenting as a Solitary Nodule Twenty-Three Years After Carotid Body Tl~.or Excision: Metastasis or Subsequent Oc- currence? Clary, C., Blaive, B., Kermarec, J., Namer, M., Philippe, C., Richelme, H. Hopital Universi-

taire et Centre Anti-Canc4reux Lacassagne,