slides 21 30

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Symmetric radial streaming Focal radial streaming Radial streaming

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Page 1: Slides 21 30

Symmetric radial streamingFocal radial streaming

Radial streaming

Page 2: Slides 21 30

Pseudopods / streaks Finger-like projections of dark pigment at the periphery of a lesion

May have small knobs at the tip

Histologically represent confluent junctional nests of melanocytes

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from Menzies et al. 2003 An atlas of surface microscopy of pigmented skin lesions

Confluent junctional nests of melanocytes of varying sizes and shapes in a melanoma

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Pseudopods

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Blue-White (Veil) An irregular indistinct An irregular indistinct whitish film whitish film superimposed on an area superimposed on an area of diffuse blue pigmentof diffuse blue pigment

If overlying the raised If overlying the raised portion of the lesion it portion of the lesion it represents dermal represents dermal melanin in combination melanin in combination with compact with compact orthokeratosisorthokeratosis

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Compact orthokeratosis and dermal melanin

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Blue-white veil

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Regression

May occur in:

Melanocytic lesions

Solar lentigines

Seborrheic keratoses

Actinic keratoses

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Well localized blue-gray dots or granules Diffuse multiple blue-gray dots or granules on a background of hypomelanosis Histologically represents melanin and fibrosis in the papillary dermis

Regression characterized by: