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Situation of Avian Influenza Situation of Avian Influenza A(H5N1) in VIETNAM A(H5N1) in VIETNAM and role of National Institute and role of National Institute of hygiene and epidemiology, of hygiene and epidemiology, hanoi, vietnam hanoi, vietnam Dr. Nguyen thi Hong hanh Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam nihe,hanoi,vietnam

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Page 1: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Situation of Avian Influenza A(H5N1) in Situation of Avian Influenza A(H5N1) in VIETNAM VIETNAM

and role of National Institute of and role of National Institute of hygiene and epidemiology, hanoi, hygiene and epidemiology, hanoi,

vietnamvietnam

Dr. Nguyen thi Hong hanhDr. Nguyen thi Hong hanh

nihe,hanoi,vietnamnihe,hanoi,vietnam

Page 2: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

ContentsContents

Situation of Avian Influenza A(H5N1).Situation of Avian Influenza A(H5N1). Role of National Institute of Role of National Institute of

Hygiene and epidemiologyHygiene and epidemiology in in Vietnam.Vietnam.

Page 3: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Situation of Avian Influenza Situation of Avian Influenza A(H5N1)A(H5N1)

Page 4: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

General Information about vietnamGeneral Information about vietnam

Area:Area: 332,600 km2332,600 km2 Provinces:Provinces: 6464 Districts:Districts: 668668 Communes/wards: Communes/wards:

10,73210,732 Population: Population: 82 82

millionsmillions

Page 5: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

THE GROWTH OF POUTRY RAISING IN VIETNAM

million

Total

Chicken

Duck

Total

Chicken

Duck

Page 6: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

POULTRY RAISING STRUCTUREPOULTRY RAISING STRUCTURE

Poultry raising at small scale: back-yards Poultry raising at small scale: back-yards and small farms: 65%.and small farms: 65%.

Poultry raising at semi-industry: 20%.Poultry raising at semi-industry: 20%. Poultry raising at industry: 15%.Poultry raising at industry: 15%. Annual growth rate: 6,5%.Annual growth rate: 6,5%.

Page 7: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

AVIAN INFLUENZA AVIAN INFLUENZA SITUATION IN SITUATION IN

VIETNAM, DEC 2003 – VIETNAM, DEC 2003 – january 2006january 2006

3 epidemic waves of avian 3 epidemic waves of avian influenza A/H5N1.influenza A/H5N1.

61 provinces reported 61 provinces reported outbreaks in poultry; 44.5 outbreaks in poultry; 44.5 million poultry killed among million poultry killed among more than 250 millions more than 250 millions poultry population.poultry population.

32 provinces32 provinces have human have human cases; Total 93 cases, 42 cases; Total 93 cases, 42 deaths (CFR: 45,2%).deaths (CFR: 45,2%).

Page 8: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam
Page 9: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

map of avian flu in vietnammap of avian flu in vietnam

Page 10: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam
Page 11: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

present timepresent time

until now:until now: - Last case A(H5N1) 13 november 2005.- Last case A(H5N1) 13 november 2005. - From 14/11/2005 untill 13/01/2006, not any - From 14/11/2005 untill 13/01/2006, not any

case is confirmed case is confirmed From 8 january 2006 until now in the From 8 january 2006 until now in the

Vietnam free of Avian InfluenzaVietnam free of Avian Influenza

Page 12: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

MAGNITUDE OF THE EPIDEMIC

1st epidemic

2nd epidemic

3rd epidemic

Page 13: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

11STST AI EPIDEMIC: AFFECTED COMMUNES AI EPIDEMIC: AFFECTED COMMUNES AND RIVER NETWORKAND RIVER NETWORK

rivers outbreaks

Page 14: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Nam §inh (1/1)* Dec 2003

Timeline and Geographic Timeline and Geographic

distribution of h5n1 cases distribution of h5n1 cases

in Vietnamin Vietnam

Bac Ninh (2/1) Jan 2004

Bac Giang (1/0) Jan 2004

Thai Binh (2/2)* Jan 2004Ha Tay (1/1) Jan 2004

HCM City (3/1) Jan 2004

Tay Ninh (2/2) Jan 2004

Soc Trang (1/1) Jan 2004

Dong Nai (2/1) Jan 2004

Lam Dong (4/3) Jan 2004

Binh Phuoc (1/1) Jan 2004

Thanh Hoa (1/0) Feb 2004

Ha Nam(2/2) Dec 2003

57 provinces had poultry outbreaks; 43.9 million poultry killed. 13 provinces have human outbreaks; 23 cases, 16 deaths; CFR: 69.6%.

wave 1: from dec 2003 to mar 2004wave 1: from dec 2003 to mar 2004

Page 15: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

17 provinces reported poultry outbreaks; 84,000 poultry killed). 3 provinces had human outbreaks; 4 cases, 4 deaths; CFR: 100%.

Hau Giang (1/1) Aug 2004

Timeline and Geographic Timeline and Geographic

distribution of h5n1 distribution of h5n1

cases in Vietnamcases in Vietnam

wave 2: from July 2004 to aug wave 2: from July 2004 to aug

20042004

Ha Noi (1/1) Aug 2004

Ha Tay (2/2) Jul 2004

Page 16: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Timeline and geographic Timeline and geographic

distribution of h5n1 distribution of h5n1

cases, in Vietnamcases, in VietnamThaiBinh (8/2) Dec 2004

Tay Ninh (3/3) Dec 2004

Dong Thap (3/3) Dec 2004

Tra Vinh (2/2) Dec 2004Hau Giang (2/2) Dec 2004

Tien Giang (1/1) Jan 2005

Long An (1/1) Jan 2005

Bac Lieu (1/1) Jan 2005

Nam §inh (1/1) Mar 2005

Ha Tay (2/1) Mar 2005

Quang Binh (5/0) Mar 2005

Ha Tinh (1/0) Mar 2005

Hai Phong (7/0) Mar 2005

Quang Tri (2/0) Mar 2005

Quang Ninh (1/1)Mar 2005

36 provinces have poultry outbreaks; 470,000 poultry killed.25 provinces have human outbreaks; 66 cases, 22 deaths; CFR: 33.3%).

wave 3: from dec 2004 wave 3: from dec 2004

until nowuntil now

Ha Noi (8/2) Jan 2005

Hung Yen (2/0) Jan 2005

Phu Tho (1/1) Jan 2005

Yen Bai (1/ 0) Apr 2005

Page 17: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

NUMBER OF AVIAN INFLUENZA CASES NUMBER OF AVIAN INFLUENZA CASES AND DEATHS BY MONTHAND DEATHS BY MONTH

0

2

4

6

8

10

12

14

16

18

20

Month/Year

Case Death

Page 18: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

DISTRIBUTION OF CASES AND DISTRIBUTION OF CASES AND

DEATHS BY AGE GROUPDEATHS BY AGE GROUP

distribution of death by age group distribution of death by age group

Tuæi

1615

22

17

4

9

3 3

16

8

47

2 0 1 00

5

10

15

20

25

30

0-9 10-19 20-29 30-39 40-49 50-59 60-69 >70

Case Death

Page 19: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

number of avian influenza cases number of avian influenza cases and deaths by genderand deaths by gender

Death by gender

50%50%

Male

Female

Case by gender

54%

46%

Male

Female

Page 20: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

family-clusters of h5n1 cases in some family-clusters of h5n1 cases in some

northern provinces, Wave 1 (2003-2004)northern provinces, Wave 1 (2003-2004)

Em g¸iEm g¸i

Thai BinhHa Nam

Nam Dinh

Hai Phong

Hai Duong

Ninh Binh

Hung Yen

20 Dec 2003

Nghia Loi, Nghia Hung

1. D. T. H (patient-unconfirmed)

2. D.V. T (brother)

26 Dec 2003

Thanh Ha, Thanh Liem

1. P.T.V (patient)

2. P. T. B (mother)

6 Jan 2004,

De Tham, Thai Binh city

1. N.L. H (patient-unconfirmed)

2. N.L. H (sister)

3. N.L H (sister)

Page 21: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Thai Binh

Vu Thu

Thai Thuy

Tien Hai

Hung Ha

Quynh Phu

Kien Xuong

Dong Hung

Thai Binh town

Thaibinh.shpDistrict.shp

N

EW

S

FAMILY-CLUSTERS OF H5N1 CASES FAMILY-CLUSTERS OF H5N1 CASES IN THAI BINH PROVINCE, WAVE 3 (2004-2005)IN THAI BINH PROVINCE, WAVE 3 (2004-2005)

26 Dec 2004

Nam Cao, Kien Xuong

1. N. H. V (patient)

2. N.H. H (brother)

3. N. H. H (brother-carrier)

14 Feb 2005

Thuy Luong, Thai Thuy

1. N. S. T (patient)

2. N. T. N (sister)

3. N. H. K (grandfather-carrier)

4. N. D. T (HCW)

19 Feb 2005

Quyet Tien, Kien Xuong

1. P.K.T (patient)

2. L.T. Them (wife-carrier)

Page 22: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Thai Binh

Hai Phong

Hai Duong

21 Mar 2005

Hung Dao, Kien Thuy

1. V. V. S (patient)

2. N. T. L (wife)

3. V. T. N (daughter)

4. V. T. T (daughter)

5. V. T. D (daughter)

Family-cluster of H5N1 cases Family-cluster of H5N1 cases in hai phong city, Wave 3 (2004-2005)in hai phong city, Wave 3 (2004-2005)

Page 23: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

REMARKS ON EPIDEMIC SITUATIONREMARKS ON EPIDEMIC SITUATION11. . Epidemics among poultryEpidemics among poultry

– Linked with two main river systems (Red Linked with two main river systems (Red and Mekong delta) – high density of ducksand Mekong delta) – high density of ducks

– 22ndnd and 3 and 3rdrd epidemics: only small farm epidemics: only small farm affected., more ducks infected than affected., more ducks infected than chickens.chickens.

2. H5N1 viruses seem to be more infectious for 2. H5N1 viruses seem to be more infectious for people:people:– Human cases occured sporadically in Human cases occured sporadically in

more provinces.more provinces.– Human cases occured in all age Human cases occured in all age

groups, with the increasing mean groups, with the increasing mean age.age.

3. Majority of human cases have 3. Majority of human cases have exposured history to infected poultry.exposured history to infected poultry.

Page 24: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

REMARKS ON EPIDEMIC SITUATIONREMARKS ON EPIDEMIC SITUATION

4. Disease patterns is changing: 4. Disease patterns is changing: Clinical symptoms become Clinical symptoms become milder, more asymptomatic milder, more asymptomatic cases; case-fatality rate is cases; case-fatality rate is decreased.decreased.

5. Genetic factors may play very 5. Genetic factors may play very important role in susceptibility to the important role in susceptibility to the virus.virus.

Page 25: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

REMARKS ON EPIDEMIC SITUATIONREMARKS ON EPIDEMIC SITUATION

6. No clear evidence of human to human 6. No clear evidence of human to human transmission is available, but it’s possibility transmission is available, but it’s possibility should be considered :should be considered :

Number of human cases increased, including Number of human cases increased, including number of healthy carriers.number of healthy carriers.

Number of infected family cluster is increasingNumber of infected family cluster is increasing Number of infected individuals in each family Number of infected individuals in each family

cluster is increasing.cluster is increasing. Some cases without clear exposure history to Some cases without clear exposure history to

sick poultry.sick poultry.

Page 26: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

REMARKS ON EPIDEMIC SITUATIONREMARKS ON EPIDEMIC SITUATION

7.Virus may have slightly changed it‘s 7.Virus may have slightly changed it‘s antigenicity and pathogenicity:antigenicity and pathogenicity:

HA gene homogeneity reduced from 99.1% HA gene homogeneity reduced from 99.1% in 2004 to 98.2% in 2005.in 2004 to 98.2% in 2005.

One amino acid deletion occurred in the One amino acid deletion occurred in the multi-basic amino acid cluster (cleavage multi-basic amino acid cluster (cleavage site), which may be associated with site), which may be associated with reduced pathogenicity.reduced pathogenicity.

Page 27: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

RESPONSESRESPONSES

1.1. National and Provincial Steering National and Provincial Steering Committee for AI epidemic prevention Committee for AI epidemic prevention and control and control (as SARS Committee)(as SARS Committee)

– The leadership of the Communist Party, and The leadership of the Communist Party, and Government.Government.

– Meeting every two weeks, especially every day Meeting every two weeks, especially every day during intensive epidemic.during intensive epidemic.

2. Set up the system for the 2. Set up the system for the identification, investigation, diagnosis identification, investigation, diagnosis and treatment of AIand treatment of AI

– Enhancing the community-based surveillance Enhancing the community-based surveillance system by providing financial incentives for AHWssystem by providing financial incentives for AHWs

– Cooperation closely with Public Health authorities. Cooperation closely with Public Health authorities.

Page 28: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

STRUCTURE OF THE NATIONAL STEERING COMMITTEE STRUCTURE OF THE NATIONAL STEERING COMMITTEE FOR SARS CONTROLFOR SARS CONTROL

national steering committee

1. Chairperson: Minister of Health. 2. Member: Ministry of Foreign Affaires, Culture and Information, Social Security, Defense, Finance, Communication and Transport, General Department of Tourism, Office of the Government

Sub-committeefor logistic

1. Chair: Director, Dept. of planning and Finance

2. Members:Office of MOH, Dept. of Personnel & Organization, Dept. Medical Equipment & Health Programes, Dept. of Drug Administration, Dept . of International Cooperation

Sub-committee for Therapy

 1. Chair: Director Dept. of Therapy - MOH

2. Members: B¹ch Mai Hospital Institute for Clinical- Research in Tropical-Medicine.Dept. of Science and Training

sub-committee for surveillance

and control1. Chairperson: Director, General Department for Preventive Medicine and HIV/AIDS Control2. Members: NIHE,Dept.of Military Health ,Military IHEDept. of Immigration,Detention Service,Border Defense command,Communication & Transport, General Dept of Tourism

Sub-committee for education

1.Chair: Director, Dept. of – Legislation - MOH

2. Members:- Dept. of International CooperationCenter for Health Communication and Education, Ministry of Foreign Affairs, Ministry of Culture and Information, Vietnam News Agency, People’s Newspaper,Vietnam Voice

Page 29: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

RESPONSESRESPONSES

Strengthening of disease surveillance.Strengthening of disease surveillance.– Upgrading diagnostic capability.Upgrading diagnostic capability.– Improving disease reporting system.Improving disease reporting system.

3. Extensive IEC on 4 measures for AI 3. Extensive IEC on 4 measures for AI prevention and control: prevention and control: mass media mass media (newspaper, TV, internet....), (newspaper, TV, internet....), distribution of distribution of pamphlets, booklets.pamphlets, booklets.

3.1 Early detection of poultry epidemic 3.1 Early detection of poultry epidemic and inform the local authorities.and inform the local authorities.

– Culling of all birds in flocks if found sero-Culling of all birds in flocks if found sero-positive with H5N1 virus or virus isolated. positive with H5N1 virus or virus isolated. Compensation for farmers.Compensation for farmers.

Page 30: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

CONSTRAINTS/CHALLENGESCONSTRAINTS/CHALLENGES

A/H5N1 avian influenza is a nA/H5N1 avian influenza is a new and emerging ew and emerging disease: lack of full knowledge about disease: lack of full knowledge about transmission mechanism, clinical spectrum, transmission mechanism, clinical spectrum, treatment and prevention.treatment and prevention.

Capacity and resources for surveillance, research Capacity and resources for surveillance, research and responses are still limited. and responses are still limited.

Some studies data show that virus maintain Some studies data show that virus maintain among ducks as asymptomatic hosts with very among ducks as asymptomatic hosts with very high prevalence, from 70%-80%.high prevalence, from 70%-80%.

There are still lack of animal health laws on There are still lack of animal health laws on transportation, quarantine, slaughtering of transportation, quarantine, slaughtering of poultry poultry

Page 31: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

CONSTRAINTS/CHALLENGESCONSTRAINTS/CHALLENGES Most households raise ducks and chickens at backyard, Most households raise ducks and chickens at backyard,

for income and food. Outbreaks may escape detection, for income and food. Outbreaks may escape detection, are difficult to control, and increase the likelihood of are difficult to control, and increase the likelihood of human exposures, which may occur when children play human exposures, which may occur when children play in areas shared by poultry or when families slaughter in areas shared by poultry or when families slaughter or prepare birds for consumption.or prepare birds for consumption.

Awareness of people about the risks of Awareness of people about the risks of infection with infection with H5N1 avian influenza is still low.H5N1 avian influenza is still low.

More effective collaboration between human and More effective collaboration between human and animal health sectors is needed.animal health sectors is needed.

The national preparedness plan for influenza pandemic The national preparedness plan for influenza pandemic prevention and control should be completed as soon as prevention and control should be completed as soon as possible.possible.

Page 32: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

STRATEGIC PLAN STRATEGIC PLAN

FOR INFLUENZA PANDEMIC FOR INFLUENZA PANDEMIC PREVENTION AND CONTROL PREVENTION AND CONTROL

IN VIETNAMIN VIETNAM

Page 33: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

OVERARCHING GOALOVERARCHING GOAL

To ensure rapid characterization of To ensure rapid characterization of the new virus subtype and early the new virus subtype and early detection, notification and rapid detection, notification and rapid response to additional cases.response to additional cases.

Page 34: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

OVERARCHING GOALOVERARCHING GOAL

early

detection early

detection Confirmativ

e diagnosis Confirmativ

e diagnosis rapid, effective

intervention

measures

rapid, effective intervention

measures

surveylance, investigatequaranty,

surveylance, investigatequaranty,

determine the most reliable

diagnostic procedure

determine the most reliable

diagnostic procedure

To early prevent

To early prevent

combination

combination

combination

combination

Page 35: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

nihenihe

Hightland IheHightland Ihe

Pasteur institute of Nha Trang Pasteur institute of Nha Trang

Pasteur institue of Hå ChÝ minh city

Pasteur institue of Hå ChÝ minh city

Page 36: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam
Page 38: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Role of National Institute of Role of National Institute of Hygiene and epidemiologyHygiene and epidemiology in in

Vietnam.Vietnam.

Page 39: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam
Page 40: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Founded in 1926: Pasteur Institute of Founded in 1926: Pasteur Institute of HanoiHanoi

1945 – 19611945 – 1961: : Institute of Institute of MicrobiologyMicrobiology

1962 – 19961962 – 1996: : Hanoi Institute of Hanoi Institute of Hygiene and EpidemilogyHygiene and Epidemilogy

1997- Until now: National Institute 1997- Until now: National Institute of Hygiene and Epidemiologyof Hygiene and Epidemiology

Development HistoryDevelopment History

Page 41: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Board of directorsBoard of directors

Admin. and logisticAdmin. and logisticdepartmentsdepartments

TechnicalTechnicaldepartmentsdepartments

Epidemiology Dept.Epidemiology Dept.

Microbiology Dept.Microbiology Dept.

Virology Dept.Virology Dept.

Molecular Bio. and Immuno. Dept.Molecular Bio. and Immuno. Dept.

Training and Research Man.Dept.Training and Research Man.Dept.

Administration Dept.Administration Dept.

Personnel Dept.Personnel Dept.

Material and Medical Material and Medical Equipment Dept.Equipment Dept.

Network Network Coordinating Dept.Coordinating Dept.

Planning Dept.Planning Dept.

National Health Program OfficesNational Health Program Offices

Center of Experimental AnimalsCenter of Experimental Animals

Company for Vaccines and Biological Production No.1

Scientific Committee

Finance & Finance & Accounting Dept.Accounting Dept.

Page 42: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Total: 472Total: 472– Professor: 7Professor: 7– Assistant Professor: 13Assistant Professor: 13– PhD: 40PhD: 40– Master: 26Master: 26

StaffStaff

Page 43: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

FunctionsFunctions

• A leading research institution responsible A leading research institution responsible for scientific and technical issues related for scientific and technical issues related to transmissible diseases control as well to transmissible diseases control as well as vaccine research and development as vaccine research and development nationwide.nationwide.

• Technical consultant for the government Technical consultant for the government of Vietnam for national policies of of Vietnam for national policies of preventive medicine and vaccination preventive medicine and vaccination strategies.strategies.

Page 44: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

FunctionsFunctions Act as leading part to direct the Act as leading part to direct the

provincial and district level (preventive provincial and district level (preventive medicine centers, epidemic preventive medicine centers, epidemic preventive hygiene groups and units); hygiene groups and units);

organize and mobilize the population as organize and mobilize the population as well as other associated authorities and well as other associated authorities and sectors in effectively penetrated sectors in effectively penetrated infectious diseases prevention and infectious diseases prevention and eradication.eradication.

Page 45: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

FunctionsFunctions

Upgrade and perfect the system of Upgrade and perfect the system of preventive medicine throughout preventive medicine throughout Vietnam, ensure the training in technical Vietnam, ensure the training in technical skills, equipment supply… for junior skills, equipment supply… for junior levels with priority given to mountain levels with priority given to mountain and island remote areas and to ethnic and island remote areas and to ethnic minorities.minorities.

Page 46: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

FunctionsFunctions

Participate in international scientific co-Participate in international scientific co-operation in order to be conversant with the operation in order to be conversant with the latest progress of preventive medical latest progress of preventive medical technology, including monitoring of technology, including monitoring of emerging and re-emerging infectious emerging and re-emerging infectious diseases, developing vaccines and diseases, developing vaccines and biological, training professional staff.biological, training professional staff.

Page 47: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Role of National Institute of Hygiene and Role of National Institute of Hygiene and epidemiologyepidemiology

NIHE has made considerable contribution to NIHE has made considerable contribution to health sector in general and public health in health sector in general and public health in particular. particular.

NIHE cooperated with other related ministries and NIHE cooperated with other related ministries and agencies to establish the preventive medicine agencies to establish the preventive medicine system for the whole country which has helped system for the whole country which has helped Vietnam obtain a remarkable success in Vietnam obtain a remarkable success in improvement of people health especially in the improvement of people health especially in the field of preventive health field of preventive health

Page 48: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Role of National Institute of Hygiene and Role of National Institute of Hygiene and epidemiologyepidemiology

Mortality and morbidity rates due to Mortality and morbidity rates due to communicable diseases which are NIHE’s communicable diseases which are NIHE’s responsibilities have been reducing annually. responsibilities have been reducing annually. Epidemics are combated relatively efficiently Epidemics are combated relatively efficiently

Suffering from SARS epidemic as many other Suffering from SARS epidemic as many other territories and countries of the world, Vietnam territories and countries of the world, Vietnam was the first country retaining the SARS was the first country retaining the SARS outbreak. Despite of lacking necessary tools outbreak. Despite of lacking necessary tools and equipments, NIHE’s staff has detected and equipments, NIHE’s staff has detected SARS virus. This has clearly contributed to the SARS virus. This has clearly contributed to the success of Vietnam in containing the epidemic.success of Vietnam in containing the epidemic.

Page 49: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Role of National Institute of Hygiene and Role of National Institute of Hygiene and epidemiologyepidemiology

As assigned by the MOH, NIHE has been As assigned by the MOH, NIHE has been responsible for implementing studies on responsible for implementing studies on virology, bacteriology and immunology, virology, bacteriology and immunology, epidemiology and so on to prevent and epidemiology and so on to prevent and control infectious diseases comprising control infectious diseases comprising circulating diseases, eliminated ones which circulating diseases, eliminated ones which tend to come back and also other emerging tend to come back and also other emerging ones ones

Page 50: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Problem and barrierProblem and barrier

the facilities are still poor; some of them the facilities are still poor; some of them are outdated because of non-are outdated because of non-synchronized and inappropriate synchronized and inappropriate investment, unable to meet the working investment, unable to meet the working demands. demands.

Some modern molecular biological Some modern molecular biological techniques cannot be implemented yet techniques cannot be implemented yet in Vietnam because of lacking in Vietnam because of lacking necessary equipments. necessary equipments.

Page 51: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Problem and barrierProblem and barrier

incapable of conducting profound studies on incapable of conducting profound studies on the viral nature and pathogenic mechanism the viral nature and pathogenic mechanism as the biosafety place with accompanying as the biosafety place with accompanying essential facilities is not available essential facilities is not available

At the moment, NIHE still does not have a At the moment, NIHE still does not have a laboratory of standard biosafety (BSL 3) in laboratory of standard biosafety (BSL 3) in order to work peacefully with hazardous order to work peacefully with hazardous microorganisms (group 4) such as anthrax, microorganisms (group 4) such as anthrax, SARS avian influenza viruses, or another ...SARS avian influenza viruses, or another ...

Page 52: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Problems and barrierProblems and barrier

due to the financial shortage, the training for due to the financial shortage, the training for NIHE staff appears to be spontaneous and NIHE staff appears to be spontaneous and part-time part-time

To quickly master advanced technology in the To quickly master advanced technology in the field of medical biology, better meet the field of medical biology, better meet the professional demand/ requirement such as professional demand/ requirement such as providing timely reliable diagnostic tests providing timely reliable diagnostic tests

it is extremely important to train and enhance it is extremely important to train and enhance the research ability of the staff in developed the research ability of the staff in developed countries with highly advanced science and countries with highly advanced science and technology technology

Page 53: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Proposals for activitiesProposals for activities

Reorganize and strengthen network Reorganize and strengthen network for early detection, confirmative for early detection, confirmative diagnosis and rapid intervention. diagnosis and rapid intervention. Set up a National Reference and Set up a National Reference and High Tech Center at NIHE in order High Tech Center at NIHE in order to improve and reassure the quality to improve and reassure the quality of confirmative diagnosisof confirmative diagnosis..

Page 54: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Proposals for activitiesProposals for activities

Confirmative diagnosisConfirmative diagnosis

Confirmative diagnosis known as the re-Confirmative diagnosis known as the re-confirmation of early detection is confirmation of early detection is performed by the combination of performed by the combination of epidemiological investigations, clinical epidemiological investigations, clinical consultation and higher-level laboratory consultation and higher-level laboratory test. test.

Page 55: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Proposals for possible Proposals for possible collaborationscollaborations

Being a country leading organization in Being a country leading organization in the field of preventive medicine and the field of preventive medicine and public health, the National Institute of public health, the National Institute of Hygiene and Epidemiology (NIHE) has Hygiene and Epidemiology (NIHE) has been also responsible for providing been also responsible for providing graduate studies in public health, graduate studies in public health, epidemiology, virology and bacteriology. epidemiology, virology and bacteriology.

Page 56: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Proposals for possible collaborationsProposals for possible collaborations

Currently NIHE would like to cooperate Currently NIHE would like to cooperate with 4 Medical Universities, who has with 4 Medical Universities, who has responsibility providing medical responsibility providing medical personals for Northern Region in order personals for Northern Region in order to enhance its training quality to enhance its training quality

Page 57: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

possible collaborationspossible collaborations 1. Undergraduate study1. Undergraduate studyto improve education quality by co to improve education quality by co

organizing training programs, organizing training programs, workshops, providing books and workshops, providing books and journals, educational materials, journals, educational materials, exchanging students and faculties in all exchanging students and faculties in all specialties including bacteriology, specialties including bacteriology, virology, epidemiology and public health virology, epidemiology and public health for undergraduate students, faculties at for undergraduate students, faculties at medical schools and health medical schools and health professionals as wellprofessionals as well..

Page 58: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

possible collaborationspossible collaborations

2 Graduate study 2 Graduate study In order to meet the need for health In order to meet the need for health professionals in the fields of public health professionals in the fields of public health and preventive medicine for the national and preventive medicine for the national preventive medicine network as an preventive medicine network as an assigned duty of NIHE, graduate study at assigned duty of NIHE, graduate study at NIHE in cooperation with NIHE in cooperation with medical medical schools schools will be enhanced by improving will be enhanced by improving training quality for Ph.D. program and training quality for Ph.D. program and launching Master program.launching Master program.

Page 59: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

possible collaborationspossible collaborations

3. Research3. Research

Enhancing close collaboration amongst Enhancing close collaboration amongst

NIHE, medical schoolsNIHE, medical schools and Preventive and Preventive Medicine Centers to carry out scientific Medicine Centers to carry out scientific researches, apply new techniques in field researches, apply new techniques in field trials.trials.

Page 60: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

Surveillance system for communicable disease in Vietnam

Ministry of healthGeneral dept. of preventive medicine

National institute of hygiene and epidemiology

General clinics, children General clinics, children clinics, infectious clinicsclinics, infectious clinics

Central hospitalsCentral hospitals

Regional Surveillance UnitRegional IHE/Pasteur Institutes

Pediatrics, infectious wardsCentral hospitals

General clinics, children clinics, infectious clinics

Provincial hospitals

Surveillance UnitProvincial Preventive

Medicine Centers

Pediatrics, infectious wardsProvincial hospitals

General clinics, children clinics, infectious clinics

District hospitals Private clinics

Surveillance Unit District surveillance teams

Commune medical station

Page 61: Situation of Avian Influenza A(H5N1) in VIETNAM and role of National Institute of hygiene and epidemiology, hanoi, vietnam Dr. Nguyen thi Hong hanh nihe,hanoi,vietnam

THANK YOU FOR YOUR THANK YOU FOR YOUR ATTENTIONATTENTION