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SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico, Steven R. Danielson, Ailan Guo, Philipp Gut, Alexandria K. Sahu, Biao Li, Radha Uppala, Mark Fitch, Timothy Riiff, Lei Zhu, Jing Zhou, Daniel Mulhern, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, Matthew P. Jacobson, Marc Hellerstein, Eric S. Goetzman, Bradford W. Gibson, Eric Verdin Cell Metabolism Volume 18, Issue 6, Pages 920-933 (December 2013) DOI: 10.1016/j.cmet.2013.11.013 Copyright © 2013 Elsevier Inc. Terms and Conditions

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Page 1: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks 

Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico, Steven R. Danielson, Ailan Guo, Philipp Gut, Alexandria K. Sahu, Biao Li, Radha Uppala, Mark Fitch, Timothy Riiff, Lei Zhu, Jing Zhou, Daniel Mulhern, Robert D. Stevens, Olga R.

Ilkayeva, Christopher B. Newgard, Matthew P. Jacobson, Marc Hellerstein, Eric S. Goetzman, Bradford W. Gibson, Eric Verdin  

Cell Metabolism Volume 18, Issue 6, Pages 920-933 (December 2013)

DOI: 10.1016/j.cmet.2013.11.013

Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 1

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 2

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 3

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 4

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 5

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 6

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Figure 7

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico,

Cell Metabolism 2013 18, 920-933DOI: (10.1016/j.cmet.2013.11.013) Copyright © 2013 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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