silver anniversary conference - american diabetes association · silver anniversary conference on...
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professional.diabetes.org/sfl
Seminole Hard Rock Hotel & Casino - Hollywood, FL 1 Seminole Way, Hollywood, FL 33314
Friday & Saturday Friday & Saturday Friday & Saturday
September 9 & September 10, 2016 September 9 & September 10, 2016 September 9 & September 10, 2016
Silver Anniversary ConferenceSilver Anniversary ConferenceSilver Anniversary ConferenceSilver Anniversary Conference on Diabetes Mellitus:
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Target AudienceTarget AudienceTarget AudienceTarget Audience
With its mul*disciplinary focus, the American Diabetes Associa*on’s 25th Annual Conference on Diabetes
Mellitus draws a1endees from across the health care spectrum and across the state of Florida. This is
South Florida’s premier diabetes mee*ng, where a1endees come to hear cu4ng-edge research translated
into clinical prac*ce, leading-edge treatment updates and the latest informa*on in diabetes management.
This mee*ng is designed specifically for physicians, pharmacists, physician assistants, nurse prac**oners,
nurses, die**ans, cer*fied diabetes educators and other health care professionals who care for pa*ents
with diabetes, at risk for diabetes, and who manage diabetes-related complica*ons.
Learning ObjectivesLearning ObjectivesLearning ObjectivesLearning Objectives
♦ Explain the cri*cal role of therapeu*c lifestyle interven*on for cardiometabolic health.
♦ Discuss the ADA/AACE glycemic targets in the hospital.
♦ Examine new classifica*on schema and therapeu*c implica*ons for diabetes
management.
♦ Outline the mechanism of ac*on of SGLT2 inhibitors.
♦ List the drug classes for treatment of type 2 diabetes.
♦ Iden*fy the mechanism of ac*on, advantages and disadvantages of available agents
used in the treatment of type 2 diabetes.
♦ Describe the history of pancreas transplanta*on.
Accreditation StatementsAccreditation StatementsAccreditation StatementsAccreditation Statements
Physicians
The American Diabetes Associa*on is accredited by the
Accredita*on Council for Con*nuing Medical Educa*on
(ACCME) to provide con*nuing medical educa*on for
physicians.
The American Diabetes Associa*on designates this edu-
ca*on ac*vity for a maximum of 11.75 AMA PRA Catego-
ry 1 credit(s)™. Physicians should only claim credit com-
mensurate with the extent of their par*cipa*on in the
ac*vity.
Doctors of Osteopathy
Category 2 credit will be awarded for formal educa*onal
programs that are ACCME-accredited or AAFP-approved.
Physician Assistants
AAPA accepts cer*ficates of par*cipa*on for educa*onal
ac*vi*es cer*fied for AMA PRA Category 1 Credit™ from
organiza*ons accredited by ACCME or a recognized state
medical society. Physician assistants may receive a maxi-
mum of 11.75 hours of Category I credit for comple*ng
this program.
Nurses
The American Diabetes Associa*on is accredited as a
provider of con*nuing nursing educa*on by the Ameri-
can Nurses Creden*aling Center’s COA.
California Board of Registered
Nursing
The American Diabetes Associa*on is also a provider ap-
proved by the California Board of Registered Nursing,
Provider No. CEP-12196. This ac*vity is approved for
11.75 contact hours.
Dietitians
The American Diabetes Associa*on is a
Con*nuing Professional Educa*on (CPE)
Accredited Provider with the Commission
on Diete*c Registra*on (CDR). Regis-
tered die**ans (RDs) and diete*c techni-
cians registered (DTRs) will receive 11.75
con*nuing professional educa*on units
(CPEUs) for comple*on of this program/material.
Pharmacists
The American Diabetes Associa*on is ac-
credited by the Accredita*on Council for
Pharmacy Educa*on as a provider of con*n-
uing pharmacy educa*on. The American
Diabetes Associa*on designates these ses-
sions as Knowledge-based per ACPE guidelines. To view
the UAN’s and learning objec*ves for each session,
please visit professional.diabetes.org/sfl aGer September
1st and click “Con*nuing Educa*on for Pharmacists.”
Attention Pharmacists: Upon closing of the
online evalua*on (September 30, 2016), the American
Diabetes Associa*on will upload the needed pharmacy-
related con*nuing educa*on informa*on to the CPE
Monitor within 60 days. The ADA is not responsible for
uploading credits aGer the evalua*on closes on Septem-
ber 30, 2016. For ques*ons, please contact profession-
aleduca*[email protected].
Certified Diabetes Educators
To sa*sfy the requirement for renewal of cer*fica*on by
con*nuing educa*on for the Na*onal Cer*fica*on Board
for Diabetes Educators (NCBDE), con*nuing educa*on
ac*vi*es must be diabetes related and approved by a
provider on the NCBDE List of Approved Providers
(www.ncbde.org). NCBDE does not approve con*nuing
educa*on. The American Diabetes Associa*on is on the
NCBDE List of Approved Providers.
CONTENT VALIDATION STATEMENTS
All recommenda*ons involving clinical medicine are
based on evidence accepted within the profession of
medicine as adequate jus*fica*on for their indica*ons
and contraindica*ons in the care of pa*ents; AND/OR
All scien*fic research referred to or reported in support
or jus*fica*on of a pa*ent care recommenda*on con-
forms to generally accepted standards of experimental
design, data collec*on, and analysis.
Successful Completion Statement Cer*ficates of Comple*on/A1endance are provided to registered a1endees based upon comple*on of the online evalua*on that will be available at
h1p://professional.diabetes.org/sfl through September 30, 2016. For ques*ons regarding con*nuing educa*on, please contact
professionaleduca*[email protected].
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
P l a n n i n g C o m m i t t e e
Paul Aoun, DO, PhD Clinical Endocrinologist, Palm Beach Diabetes &
Endocrine Specialists; University of Miami
Miller School of Medicine; JFK Medical Center
Boynton Beach, FL
Pamela C. Arnold, MSN, APRN, BC-
ADM, CDE Diabetes Program Manager
Medical University of South Carolina
Charleston, SC
Katherine Chadwell, DNP, MBMSc,
ARNP, GNP-BC, CPHQ Associate Professor
Florida Atlan*c University
Chris*ne E. Lynn College of Nursing
Boca Raton, FL
James R. Gavin III, MD, PhD CEO and Chief Medical Officer, Healing Our
Village, Inc.; Clinical Professor of Medicine,
Emory University School of Medicine
Atlanta, GA
Harvi Anne Lipshultz, BS Pharm,
PharmD Clinical Research Pharmacist
Broward Health
Fort Lauderdale, FL
Mudit Jain, MD, FACE, ECNU, CDE Director, Diabetes & Thyroid Care Center of
Excellence; Clinical Assistant Professor,
Nova Southeastern University; Florida Interna-
*onal University
Planta*on, FL
Michael Ozner, MD, FACC, FAHA Medical Director, Center for Preven*on and
Wellness, Bap*st Health South Florida;
Voluntary Assistant Professor of Medicine,
University of Miami Miller School of Medicine
Miami, FL
Alvin (Al) Powers, MD Joe C. Davis Chair in Biomedical Science;
Professor of Medicine, Molecular Physiology
and Biophysics; Director, Vanderbilt Diabetes
Center; Chief, Division of Diabetes, Endocrinolo-
gy, and Metabolism, Vanderbilt University
School of Medicine
Nashville, TN
Lital Reitblat, MD, MS Pediatric Endocrinologist
Broward Health
Fort Lauderdale, FL
Julie Rodman, OD, MS, FAAO Associate Professor of Optometry
Nova Southeastern University
Fort Lauderdale, FL
Marile Santamarina, MS, PharmD,
CPh, CDE, CPT Assistant Professor of Pharmacy Prac*ce,
Palm Beach Atlan*c University; Cleveland Clinic
West Palm Beach, FL
Teresa J. Sakraida, MS, MSED, PhD,
RN Associate Professor
Florida Atlan*c University
Chris*ne E. Lynn College of Nursing
Boca Raton, FL
Stanley Schwartz, MD Associate Professor, University of Pennsylvania;
Director of Diabetes Program, Philadelphia
Heart Ins*tute
Philadelphia, PA
David Sutherland, MD, PhD Emeritus Professor of Surgery
University of Minnesota
Minneapolis, MN
Stacy Winton, MS, RDN, LD/N Clinical Nutri*onist
Memorial Regional Hospital
Hollywood, FL
S p e a ke r s a n d P r e s e n t e r s
Monique Biddle, RD, LD, CDE
Diabetes Nutrition Specialist
Memorial Regional Hospital
Diabetes Center
Hollywood, FL
Lois Exelbert, RN, CDE, MS, BC-ADM
Manager,
Baptist Hospital Diabetes Care Center
Miami, FL
Siobhan Gross, RN, BSN, CDE
Registered Nurse,
Certified Diabetes Educator
Jupiter Medical Center
Jupiter, FL
Alan Jacobson, BS, RPh, DPM
Retired
Andrea Jacobson, RN, BSN, CDE
RN Pediatric Endocrinology
Joe DiMaggio Children’s Hospital
Hollywood, FL
Mudit Jain, MD, FACE, ECNU, CDE
Director
Diabetes & Thyroid Care Center of
Excellence
Plantation, FL
Jeanna Rhoulhac, RDN, CDE, CDTC,
LD/N
Broward Health,
Community Health Services
Clinical Nutri*onist
Specialty Care Center
Fort Lauderdale, FL
Teresa J. Sakraida, MS, MSED, PhD, RN
Associate Professor
Florida Atlan*c University
Chris*ne E. Lynn College of Nursing
Boca Raton, FL
Marile Santamarina, MS, PharmD, CPh,
CDE, CPT
Assistant Professor
Palm Beach Atlan*c University
Palm Beach, FL
Thelma Williams, RN, MSN-ED, BSN, NCC,
CNS, DNS
Program Manager
Florida Medical Center
Lauderdale Lakes, FL
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
P l a n n i n g C o m m i t t e e
Paul Aoun, DO, PhD
Disclosed no conflict of interest.
Pamela C. Arnold, MSN, APRN, BC-ADM,
CDE
Disclosed no conflict of interest.
Katherine Chadwell, DNP, MBMSc, ARNP,
GNP-BC, CPHQ
Disclosed no conflict of interest.
James R. Gavin III, MD, PhD
Board Member/Advisory Panel: Abbo1
Diabetes Care; Intarcia Pharmaceu*cals;
Janssen Pharmaceu*cals
Consultant: Intarcia Pharmaceu*cals; Novo
Nordisk
Speaker’s Bureau: AstraZeneca; Boehringer
Ingelheim; Janssen Pharmaceu*cals
Harvi Lipshultz, PharmD
Disclosed no conflict of interest.
Mudit Jain, MD, FACE, ECNU, CDE
Speaker’s Bureau: AstraZeneca; Boehringer
-Ingelheim; Lilly
Michael Ozner, MD, FACC, FAHA
Scien*fic Advisory Board: Life Extension;
Nordic Naturals
Alvin (Al) Powers, MD
Disclosed no conflict of interest.
Lital Reitblat, MD
Disclosed no conflict of interest.
Julie Rodman, OD, MS, FAAO
Consultant: Optorue
Marile Santamarina, MS, PharmD, CPh,
CDE, CPT
Disclosed no conflict of interest.
Teresa J. Sakraida, MS, MSED, PhD, RN
Disclosed no conflict of interest.
Stanley Schwartz, MD
BoardMember/Advisory Panel: Janssen;
Merck; AstraZeneca; Boehringer-
Ingelheim; Lilly; Salix, Novo Nordisk, Gene-
sis Biotech
Consultant: NIH ROIDK085212
Speaker’s Bureau: Janssen; Merck; Astra-
Zeneca; Boehringer-Ingelheim; Lilly; Salix,
Novo Nordisk, Eisai, Inc.; Amgen
Stock Holder: Saturn
David Sutherland, MD, PhD
Disclosed no conflict of interest.
Stacy Winton, MS, RDN, LD/N
Disclosed no conflict of interest.
S p e a ke r s a n d P r e s e n t e r s
Monique Biddle, RD, LD, CDE Disclosed no conflict of interest.
Lois Exelbert, RN, MS, CDE, BC-ADM,
LCCE
Disclosed no conflict of interest.
Siobhan Gross, RN, BSN, CDE Disclosed no conflict of interest.
Alan Jacobson, BS, RPh, DPM Disclosed no conflict of interest.
Andrea Jacobson, RN, BSN, CDE Disclosed no conflict of interest.
Mudit Jain, MD, FACE, ECNU, CDE
Speaker’s Bureau: AstraZeneca;
Boehringer-Ingelheim; Lilly
Jeanna Rhoulhac, RDN, CDE, CDTC,
LD/N Disclosed no conflict of interest.
Teresa J. Sakraida, MS, MSED, PhD,
RN Disclosed no conflict of interest.
Marile Santamarina, MS, PharmD, CPh,
CDE, CPT
Disclosed no conflict of interest.
Thelma Williams, RN, MSN-ED Disclosed no conflict of interest.
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
As an accredited provider of con*nuing educa*on, it is the Associa*on’s policy to ensure balance, inde-
pendence, objec*vity, and scien*fic rigor in all of its educa*onal ac*vi*es. All par*cipa*ng faculty and
planning commi1ee members are required to disclose to the program audience any financial rela*on-
ships related to the subject ma1er of this program. Disclosure informa*on is reviewed in advance in or-
der to manage and resolve any possible conflicts of interest. The intent of this disclosure is to provide
par*cipants with informa*on on which they can make their own judgments.
D i s c l o s u r e I n f o r m a t i o n
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
P R O G R A M S C H E D U L E
7:00 AM - 7:45 AM Registra*on
Con*nental Breakfast
Exhibits Open
7:45 AM - 8:00 AM Welcome - Mitchell Cypress, President of the Seminole Tribe of Florida
8:00 AM - 9:00 AM New Theories of Classifying Diabetes
Stanley Schwartz, MD
9:00 AM - 10:00 AM Cardiovascular Disease: Reflec:ng Back and Moving Forward
Michael Ozner, MD, FACC, FAHA
10:15 AM - 11: 15 AM History and Current Status of Pancreas Transplanta:on
David Sutherland, MD
11:15 AM- 12:15 PM Herbal Remedies for Adjunc:ve Treatment of Diabetes
Harvi Anne Lipshultz, PharmD
12:15 PM- 1:00 PM Expert Panel with Q & A
Stanley Schwartz, MD; Michael Ozner, MD, FACC, FAHA;
David Sutherland, MD; Harvi Anne Lipshultz, PharmD
1:00 PM—2:30 PM LUNCH BREAK
10:00 AM - 10:15 AM MID-MORNING BREAK & EXHIBITS
KEYNOTE SESSIONS
2:30 PM—4:30 PM AFTERNOON WORKSHOPS
GRAND BALLROOM C GRAND BALLROOM D MTG. ROOMS 1 & 2
2:30 pm - 3:30 pm
Pharmacy in Your Pantry
Stacy Winton, MS, RDN, LD/N
Diabe:c Re:nopathy
Eye Update
Julie Rodman, OD, FAAO
Diabetes and Personalized
Healthcare—Why Genes MaEer
Katherine Chadwell, DNP, MBMSc,
ARNP, GNP-BC, CPHQ
3:30 pm - 4:30 pm
SGLT-2 Inhibitors:
Review of Safety Issues
Marile Santamarina, MS, PharmD, CPh,
CDE, CPT
Health Behavior Change:
An Update on the State of the
Science and Future Think
Teresa Sakraida, MS, MSED, PhD, RN
Exercise Concerns
in Youth with Type 1
Lital Reitblat, MD
7:00 AM - 7:45 AM Registra*on
Con*nental Breakfast
Exhibits Open
7:45 AM - 8:00 AM Welcome
8:00 AM - 9:00 AM Diabetes Epidemiology: Guiding Clinical and Public Health Prac:ce
Jim Gavin, MD, PhD
9:00 AM—10:00 AM Diabetes Management in the Hospital SeFng
Pamela C. Arnold, RN, MSN, CDE, APRN
10:15 AM - 11:15 AM Effec:ve Solu:ons to Common Diabetes Care Challenges
Paul Aoun, DO, PhD
11:15 AM - 12:15 PM Recent Advances in Pharmacotherapy for Type 2 Diabetes
Mudit Jain, MD, FACE, ECNU, CDE
12:15 PM - 1:15 PM Changes in the Understanding of Pathogenesis of Type 1 Diabetes: Implica:ons for
Preven:on and Treatment
Al Powers, MD
10:00 AM - 10:15 AM MID-MORNING BREAK & EXHIBITS
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
P R O G R A M S C H E D U L E
KEYNOTE SESSIONS
Presentation Handouts
Just as a reminder, in an effort to go green, select presenta*on handouts are located on our website and
available for download: professional.diabetes.org/sfl
Successful Completion Statement
Cer*ficates of Comple*on/A1endance are provided to registered a1endees based upon comple*on of the
online evalua*on that will be available at h1p://professional.diabetes.org/sfl through September 30 2016.
For ques*ons regarding con*nuing educa*on, please contact professionaleduca*[email protected]
PERSONAL SESSION TRACKING WORKSHEET FOR PHARMACIST
**Double Credit will not be awarded for sessions occurring at the same time.
Time Sessions Number of
credits/hours
Friday, September 9, 2016
8:00 am - 9:00 am New Theories of Classifying Diabetes
UAN: 0239-0000-16-302-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Discuss the benefits and challenges with exis*ng classifica*on of diabetes
mellitus
1.0
9:00 am—10:00 am Cardiovascular Disease: Reflec:ng Back and Moving Forward
UAN: 0239-0000-16-303-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Iden*fy the root cause of atherosclerosis
• Explore the cri*cal role of therapeu*c lifestyle interven*on for
cardiometabolic health
• Indicate key cardiac risk factors and learn how to reverse them
1.0
10:15 am—11:15 am History and Current Status of Pancreas Transplanta:on
UAN: 0239-0000-16-304-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the history of pancreas transplanta*on
• Outline guidelines for pa*ent elec*on for pancreas transplanta*on
• Describe current pancreas transplanta*on outcomes for pa*ents
1.0
11:15 am - 12:15 pm Herbal Remedies for the Adjunc:ve Treatment of Diabetes
UAN: 0239-0000-16-305-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Outline unbiased, historically and clinically significant data on the
adjunc*ve use of herbal remedies in diabe*c pa*ents.
1.0
12:15pm—1:00 PM Expert Panel with Q&A
UAN: 0239-0000-16-306-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Discuss the ADA/AACE glycemic targets in the hospital.
• Discuss the benefits and challenges with exis*ng classifica*on of diabetes
mellitus
0.75
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Time Concurrent Sessions Number of
credits/hours
Friday, September 9, 2016
2:30 pm - 3:30 pm Pharmacy in Your Pantry
UAN: 0239-0000-16-307-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the impact of diabetes on the eye including classifica*on and
treatment.
1.0
Diabe:c Re:nopathy Eye Update
UAN: 0239-0000-16-308-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the impact of diabetes on the eye including classifica*on and
treatment.
1.0
Diabetes and Personalized Healthcare—Why Genes MaEer
UAN: 0239-0000-16-309-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Summarize the personalized healthcare ini*a*ve
• Define the basic concepts of gene*cs, genomics, and epigene*c
• Iden*fy the role of the healthcare provider in the treatment and
development of diabetes from a personalized approach to diabetes
1.0
3:30 pm - 4:30 pm SGLT-2 Inhibitors: Review of Safety Issues
UAN: 0239-0000-16-310-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the mechanism of ac*on of SGLT2 inhibitors.
• List the 3 most common side effects of SGLT2 inhibitors.
• State 3 monitoring parameters that individuals using an SGLT2 inhibitor
should performed to prevent or early detect DKA, a rare side effects of
SGLT2 inhibitors.
1.0
Health Behavior Changes: An Update on the State of the Science and Future
Think
UAN: 0239-0000-16-311-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• List barriers to diabetes self-management.
• Outline the state of the science literature about health behavior change.
1.0
Exercise Concerns in Youth with Type 1
UAN: 0239-0000-16-312-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Iden*fy challenges for young people with Type 1 diabetes when trying to
exercise
• Explain the physiology of glucose u*liza*on during exercise in Type 1
diabetes.
• Iden*fy ways to promote euglycemia during and aGer exercise for your
people with Type 1 diabetes.
1.0
Total for
Friday 6.75
PERSONAL SESSION TRACKING WORKSHEET FOR PHARMACIST
**Double Credit will not be awarded for sessions occurring at the same time.
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
PERSONAL SESSION TRACKING WORKSHEET FOR PHARMACIST
**Double Credit will not be awarded for sessions occurring at the same time.
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Time Sessions Number of
credits/hours
Saturday, September 10, 2016
8:00 am - 9:00 am Diabetes Epidemiology: Guiding Clinical and Public Health Prac:ce
UAN: 0239-0000-16-313-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the influence epidemiological findings have had on clinical
and public health approaches to trea*ng diabetes
1.0
9:00 am—10:00 am Diabetes Management in the Hospital SeFng
UAN: 0239-0000-16-314-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Discuss the ADA/AACE glycemic targets in the hospital.
1.0
10:15 am - 11:15 am
Effec:ve Solu:ons to Common Diabetes Care Challenges
UAN: 0239-0000-16-315-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Iden*fy the mechanism of ac*on, advantages and disadvantages of
available agents used in the treatment of type 2 diabetes.
1.0
11:15 am—12:15 pm
Recent Advances in Pharmacotherapy for Type 2 Diabetes
UAN: 0239-0000-16-316-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• List the drug classes for treatment of type 2 diabetes.
1.0
12:15 pm - 1:15 pm
Changes in the Understanding of Pathogenesis of Type 1 Diabetes:
Implica:ons for Preven:on and Treatment
UAN: 0239-0000-16-317-L01-P
At the end of this presenta:on, the par:cipant should be able to:
• Describe the history of pancreas transplanta*on.
1.0
Total for
Saturday 5.0
TOTAL CREDIT HOURS AVAILABLE OVERALL
TOTAL: 11.75
TOTAL CREDIT HOURS EARNED
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Exhibitors AstraZeneca
Bap*st Health South Florida
Janssen Pharmaceu*cal Inc.
Lilly, USA LLC
Merck
Novo Nordisk
PTS Diagnos*cs
P&G
Sanofi
TrialNet
Bap*st Health South Florida
Humana
MannKind Corp.
Memorial Healthcare System
P&G
Thank You To Our Generous
Sponsors and Supporters!
PRODUCT THEATER
Presented by MannKind Corp.
1:00 p.m. – 2:00 p.m. LUNCH PRODUCT THEATER ~ Grand Ballroom A & B
Update on Prandial Insulin for the Treatment of Type 1 Diabetes – Affinity 1 Study
Dr. Mudit Jane, Dr. Mudit Jane, Dr. Mudit Jane, Dr. Mudit Jane, MD, FACE, ECNU, CDE
MannKind Corpora*on is a biopharmaceu*cal company focused on the discovery, development and
commercializa*on of therapeu*c products for pa*ents.
AFREZZA® (pronounced uh-FREZZ-uh), approved in 2014 by the U.S. Food and Drug Administra*on is
a rapid-ac*ng inhaled insulin therapy indicated to improve glycemic control in adults with diabe-
tes. Taken at the start of a meal using a specially designed inhaler, Afrezza dissolves rapidly upon
inhala*on to the deep lung and delivers insulin quickly to the bloodstream. Peak insulin levels are
achieved within 12 to 15 minutes of use and help to control post-meal blood sugar spikes that affect
HbA1C levels.
AFREZZA u*lizes our proprietary Technosphere® formula*on technology , which is based on a class
of organic molecules that are designed to self-assemble into small par*cles onto which drug mole-
cules can be loaded. We believe Technosphere represents a versa*le drug delivery plaVorm that
may allow pulmonary administra*on of certain drugs that currently require administra*on by injec-
*on, such as GLP-1. Pulmonary administra*on provides convenience for the pa*ent and we believe
a major advantage of drugs inhaled as Technosphere formula*ons is that they have been shown to
be absorbed very rapidly into the arterial circula*on, essen*ally mimicking intra-arterial administra-
*on. MannKind is also developing other inhala*on technologies, including an innova*ve line of pa-
*ent-focused, breath-ac*vated, dry powder inhalers and inhala*on profiling to characterize pa*ent
inhala*on.
*This program is sponsored by and the speaker is presen�ng on behalf of MannKind Corp. It is being presented
consistent with FDA guidelines and is not approved for con�nuing educa�on credit.
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
Silver Anniversary ConferenceSilver Anniversary ConferenceSilver Anniversary ConferenceSilver Anniversary Conference on Diabetes Mellitus:
Silver Anniversary Conference on Diabetes Mellitus: Reflec*ng Back, Moving Forward
This ac:vity is supported, in part, by an educa:onal
grant from
Lilly, USA LLC