service catalog 2019 · yellow fever mosquito aedes aegypti malaria mosquito anopheles gambiae...
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ANALYTICS EFFICACY INSECTSDEVELOPMENT
SERVICE CATALOG2019
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Notes
4 - 7 Analytics and Application Testing
8 - 10 Biological Product Testing
11 Product Development
12 - 14 Test Insects
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I N D E X360°
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petent Test Institute.
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General InformationANALYTICS
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Analytics and Application TestingOur service portfolio for product analysis and application testing
The analytical services of BioGenius can be performed according to the OECD GLP guideline as well as under NON-GLP conditions.
Therefore BioGenius is capable of supporting its customers with data packages for any product authorization according to international
regulations like:
– Biocidal Products Regulation 528 / 2012– AVPMA and US EPA– Plant Protection Products Regulation 1107 / 2009– EC 440 / 2008 (REACH)
as well as further international product authorization requirements.
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Analytical Data Packages
Description Methods
1. Analytical method development for active ingredients and products
• Insecticides, repellents and attractants• Rodenticides• Wood preservation• Disinfectants, hygiene and preservatives• Water treatment and metal working fluids
2. Validation of analytical methods for product authorization
• GC-FID/MS, HPLC-UV/MS, IC, titration, UV-VIS photometry
SANCO 3030 / 99
3. 5-Batch analyses of actives, active isomers, co-formulants and impurities in accordance to BPR and PPP
• Method development• Method transfer• Method validation
5. Determination of content for active substances, impurities and by-products
• PT 18 and 19 Insecticides and repellents• PT 1 - 6 Disinfectants, hygiene and preservatives• PT 14 Rodenticides• PT 11 and 13 Water treatment and metal working fluids• PT 8 Wood preservation
Other product types on request.
4. Shelf life studies for product authorization and preliminaryscreening tests
• Low temperature stability of product and packaging
• Accelerated stability of product and packaging
54 °C, 40 °C, 35 °C, 30 °C
• Ambient stability of product and packaging
20 °C, 25 °C, 30 °C
• Stability against metals and ions
The studies can be combined with all necessary application parameters which are required for the product authorization. Other temperatures between -20 °C and 70 °C are also possible.
CIPAC MT 39.3
CIPAC MT 46.3
OPPTS 830.6313
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ANALYTICS
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Description Methods
New
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6. Physico-chemical properties for product authorization
6.1 Spray Application (bag on valve spray, pressurized aerosol, trigger spray, etc.)
• Intermediate appearance (colour, odour and physical state)• Packaging stability (incl. seepage data)• Weight loss• Particle size distribution (using Malvern Spraytec laser evaluation)• Density of intermediate / propellant mix.• Spray pattern (homogeneity of the spray picture, diameter, etc.)• Total discharge / residue after use incl. valve clogging• Discharge rate• Can pressure (20 °C and 50 °C)
CIPAC MT 187A.03 / FEA 605FEA 644WHO / FAOFEA 643FEA 604 / 606
6.2 Liquid Application (suspension concentrate, emulsion concentrate, etc.)
• Formulation appearance (colour, odour and physical state)• Packaging stability (incl. seepage data)• Weight loss• Viscosity• Rel. density• pH-value• Acidity / alkalinity• Refractive index• Surface tension• Particle size distribution (using Malvern spraytec laser evaluation)• Persistent foaming• Suspensibility• Dispersion stability• Dilution stability• Emulsion stability • Pourability of suspension concentrates• Water content (Karl-Fischer)• Wet sieving• Spontaneity of dispersion
OECD 114 / CIPAC MT 192 / MT 22.1OECD 109 / EC A.3OECD 122 / CIPAC MT 75.3OECD 122 / CIPAC MT 191
OECD 115 / EC A.5CIPAC MT 187CIPAC MT 47.2 / 47.3CIPAC MT 184CIPAC MT 180CIPAC MT 41 / 41.1CIPAC MT 36.3CIPAC MT 148 / 148.1CIPAC MT 30.5CIPAC MT 185CIPAC MT 160
6.3 Solid Application (granular, tablet, paste, block, etc.)
• Formulation appearance (colour, odour and physical state)• Packaging stability (incl. seepage data)• Weight loss• Particle size distribution of powders (using Malvern spraytec laser evaluation)• Bulk density• Wettability• Suspensibility• Sieve analysis, dry sieving• Attrition resistance• Friability of tablets• Flowability• Dustiness• Water content (Karl-Fischer)• Disintegration time of tablets• Dissolution rate of water soluble bags• Wet sieving• Loss on drying• Spontaneity of dispersion of water dispersible granules• Degree of dissolution and dilution stability• pH-value• Acidity / alkalinity• Persistent foaming• Tablet integrity
CIPAC MT 187CIPAC MT 186CIPAC MT 53.3CIPAC MT 184CIPAC MT 170CIPAC MT 178 / 178.2CIPAC MT 193CIPAC MT 172CIPAC MT 171.1CIPAC MT 30.5CIPAC MT 197CIPAC MT 176CIPAC MT 185CIPAC MT 17.4CIPAC MT 174CIPAC MT 179OECD122 / CIPAC MT 75.3OECD122 / CIPAC MT 191CIPAC MT 47.2 / 47.3WHO / M / 27
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ANALYTICS
6.4 Safety data packages for product authorization
In-house• Melting point• Boiling point• Rel. density• Surface tension• Flash point• Flammability solids, screening or complete test• Oxidising properties for solids• Corrosion testing
External• Vapour pressure• Water solubility flask method or column elution method• Flammability gases, screening or complete test• Flammability contact with water• Pyrophoric properties• Explosive properties• Auto ignition temperature (liquids and gases)• Rel. self ignition temperature for solids• Oxidising properties liquids• Flash point• Flammability solids, screening or complete test• Oxidising properties for solids• Flame length and ignition distance of spray cans• Drum test (space ignition of spray cans)
EC A.1EC A.2EC A.3EC A.5EC A.9EC A.10EC A.17UN C.1 Section 37.4
EC A.4EC A.6EC A.11EC A.12 / UN N.5EC A.13 / UN N.2 / N.3EC A.14 / UN 1 (c), 2 (c), C.1EC A.15EC A.16 / UN N.4EC A.21 / UN O.2UN L.2UN N.1UN O.1 / O.3UNUN
7. Specific studies and application testing
• Evaporation properties of vaporizer products• Residue of active ingredients in vaporizer products after use• Product treatment properties during use• Stain tests to determine colour or liquid stains on fabrics or other surfaces
Gravimetrical or in-house Analytical methods
In-house method
8. Determination of active ingredient concentration in spaces
• Concentration of active ingredients during usage time
• Determination of max. concentration and degradation of active ingredients during use
• Determination of active ingredient and residues on surfaces during and after use
In accordance with data requirements for product Exposure scenarios and product risk assessments
NON-GLP
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Description Methods
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ANALYTICS
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The efficacy test services of BioGenius can be performed analogous to GLP.
Therefore BioGenius is capable of supporting its customers with data packages for product screening as well as for product authorization
according to the following international regulations:
– Guidance on the Biocidal Products Regulation according to BPR 528 / 2012– WHO guidelines
and further international product authorization requirements.
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Biological Product TestingOur service portfolio for efficacy testing of „insecticide“ and repellent products
General InformationEFFICACY
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Target Description Methods
1. Cockroaches - Direct spray treatment- Residual effect on surfaces- Cockroach bait testing- Flushing effect- Egg stopper effect- Secondary kill („Domino effect“)- Space effect- Repellent effect
2. Ants - Direct spray treatment- Residual effect on surfaces- Ant bait tests against workers (kill)- Ant bait tests (colony kill)- Attractiveness- Repellent and space (repellent) effect
3. Termites - Residual effect on surfaces- Direct spray treatment
4. Bed bugs - Residual effect on surfaces- Direct spray treatment- Space effect- Tests with treated fabric
5. Ticks - Tests for skin repellent- Tests with treated fabric- Residual effect on surfaces- Direct spray treatment- Space effect
6. Mites - Efficacy against house dust mites- Residual effect against house dust mites- Repellent effect against house dust mites- Direct spray treatment red poultry mites- Space effect red poultry mites
7. Fleas - Direct spray treatment- Residual effect on surfaces- Larvicidal effect- Space effect
For all test insects:Screening testsDevelopment testsComparative tests
Registration tests: - lab test - simulated-use test - field test
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EFFICACY
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Target Description Methods
Test rooms
9. Textile attacking insects
- Moth product testing in cabinets / drawers- Repellent effect on clothes moths- Test of traps- Larvicidal effect against clothes moth- Larvicidal effect against carpet bettles- Carpet beetle tests in cabinets / drawers- Textile damage (woolmark method ISO 3998)- Space effect
10. Stored goods-attacking insects
- Test of glue/pheromone traps- Direct spray treatment- Larvicidal effect- Space effect
11. Flies - Aerosol tests- Residual effect on surface / in rooms- Efficacy of fly catcher / window sticker- Arm in cage test / space repellent effect- Larvicidal effect- Attractivness of baits- Bait tests
12. Mosquitoes - Aerosol tests- Residual effect on surface / in rooms- Arm in cage tests for skin repellent- Arm in cage tests using treated fabrics- Efficacy of bed nets against mosquitoes- Larvicidal effect- Efficacy in air crafts- Space effect (repellent)
13. Wasps - Colony kill- Surface repellent effect- Direct spray treatment- Space effect
14. Other species silverfish, woodlice, spiders, earwigs
8. Litter beetles - Residual effect on surfaces- Direct spray treatment- Larvicidal effect- Space effect
• 4 chambers with 20 m³• 8 rooms with 30 m³ (4 rooms can be combined to an apartment)• 2 rooms with 44 m³• Large space room up to 700 m³• Different smaller sized chambers (0.5 m³ | 2.0 m³)• Tent and hut simulation equipment
For all test insects:Screening testsDevelopment testsComparative tests
Registration tests: - lab test - simulated-use test - field test
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EFFICACY
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We proof We create We develop We verify
Productideas
Formulationconcepts
Formulationsand products
Productrealisation
√ „Me too“ Concept
√ Innovative
√ Actives
√ Co-formulants
√ Application
√ Packaging material
√ Design
√ Composition
√ Function
√ Packaging
√ Application
√ Formulation
√ Claim
√ Manufacturing
√ Safety
√ Registration
We develop
Innovativetechnologies
Pro activeinvention of
√ Insecticide√ Repellent
technologies
BioGenius is capable of supporting its customers in the development of their own new product ideas.
Uniquely in the area of product development we provide a 360° service for a wide range of applications. We integrate all fields of influence
from the beginning up to the finished product.
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Product DevelopmentOur service portfolio for product development,application technique and product invention
General InformationDEVELOPMENT
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petent Test Institute.
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Test Insects
General InformationINSECTS
The insect breeding of BioGenius fulfills the requirements for testing of professional and consumer products.
In combination with our efficacy test services BioGenius is capable of supporting its customers with product screening and product authorization
data according to the following international regulations:
- Guidance on the Biocidal Products Regulation according to BPR 528 / 2012- WHO guidelines
as well as further international product authorization requirements.
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petent Test Institute.
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Hygiene Pests
INSECTS
New
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Cockroaches (Blattodea)German cockroach Blattella germanicaResistant German cockroach Blattella germanica (resistant)Oriental cockroach Blatta orientalisAmerican cockroach Periplaneta americanaBrown-banded cockroach Supella longipalpa
Flies (Diptera)Common green bottle fly Lucilia sericataHouse fly Musca domesticaStable fly Stomoxys calcitransFruit fly Drosophila melanogasterYellow fever mosquito Aedes aegyptiMalaria mosquito Anopheles gambiaeHouse mosquito Culex quinquefasciatusAsian tiger mosquito Aedes albopictus
Bugs (Heteroptera)Bed bug Cimex lectulariusResistant Bed bug Cimex lectularius (resistant)
Fleas (Siphonaptera)Cat flea Ctenocephalides felis
Ants (Hymenoptera)Pharaoh ant Monomorium pharaonisBlack garden ant Lasius niger
Arachnids (Arachnida)House dust mite Dermatophagoides farinaeHouse dust mite Dermatophagoides pteronyssinusRed poultry mite Dermanyssus gallinaeEuropean sheep tick Ixodes ricinusBrown dog tick Rhipicephalus sanguineus
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Material Pests
Stored Product Pests
Nuisance Arthropodes
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Clothes moth Tineola bisselliellaTermites Reticulitermes grasseiCarpet beetle Anthrenus flavipes
Indian meal moth Plodia interpunctellaMediterranean flour moth Ephestia kuehniellaFlour beetle Tribolium confusumLesser mealworm Alphitobius spp.Yellow mealworm Tenebrio molitorGrain weevil Sitophilus granarius
Silverfish Lepisma saccharinaWoodlouse Porcellio scaberYellow jacket Vespula spp.Garden spider Araneus diadematusDaddy long leg spider Pholcus spp.
Further species on demand.
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petent Test Institute.
INSECTS
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Notes
www.biogenius.de
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BioGenius GmbHTechnologiePark, Campus 1
Friedrich-Ebert-Straße 7551429 Bergisch Gladbach, Germany
Phone +49 (0) 2204 830 77-0Fax +49 (0) 2204 830 77-11