second sls presentation from beth israel

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Society of Laparoendoscop ic Surgeons 2009 Prospective Evaluation of Endoscopic Plication and Reduction of Gastric Pouch in Patients who Previously Underwent Gastric Bypass Surgery Chiranjiv S Virk MD, Dimitrios V. Avgerinos, MD, Radha Patel, Burton Surick, MD, John L. Holup, DO, Elliot R. Goodman, MD and I. Michael Leitman, MD Department of Surgery Beth Israel Medical Center New York, NY

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More data presented at SLS meeting in Boston Sept 2009

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Page 1: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Prospective Evaluation of Endoscopic Plication and Reduction of Gastric Pouch in Patients who Previously Underwent Gastric

Bypass Surgery

Prospective Evaluation of Endoscopic Plication and Reduction of Gastric Pouch in Patients who Previously Underwent Gastric

Bypass Surgery

Chiranjiv S Virk MD, Dimitrios V. Avgerinos, MD, Radha Patel, Burton Surick, MD, John L. Holup, DO, Elliot R. Goodman, MD and I. Michael Leitman, MD

Department of Surgery

Beth Israel Medical Center

New York, NY

Chiranjiv S Virk MD, Dimitrios V. Avgerinos, MD, Radha Patel, Burton Surick, MD, John L. Holup, DO, Elliot R. Goodman, MD and I. Michael Leitman, MD

Department of Surgery

Beth Israel Medical Center

New York, NY

Page 2: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Commercial Disclosures:Commercial Disclosures:

StomaphyX ® is a product of EndoGastric Solutions ®(Redmond, WA).

None of the authors have any financial relationship with EndoGastric Solutions ®.

StomaphyX ® is a product of EndoGastric Solutions ®(Redmond, WA).

None of the authors have any financial relationship with EndoGastric Solutions ®.

Page 3: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Results (N=64)Results (N=64)

Age (years) 47.5 (24-66)

Female / Male 92% female / 8% male

Height (inches) 65

Median BMI Pre-Gastric Bypass 48.7

Median BMI Post-Gastric Bypass (nadir)

31.3

Median BMI Post-GB(nadir) 31.3

Median time(years) after Gastric bypass surgery

5 (2-10)

Page 4: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Median BMI before StomaphyX

39.85 (25.9-54.9)

Median BMI post Stomaphyx

37.75(25.1-55.2)

Median follow up(months)

6(1-13)

No. Patients Weight loss

43(67%)

No. Patients no weight loss

14(21%)

No follow up weight available

7(12%)

Page 5: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Median weight loss (lbs.) post StomaphyX

15.5(3.3-67)

Median OR time 50 (35-130)

Median reduction in gastric pouch length

33%(0-67)

Median # of fasteners

23(10-40)

Page 6: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

RESULTSRESULTS

Dumping syndrome improved

GERD improved

Dumping syndrome improved

GERD improved0

5

10

15

20

25

30

35

40

Pre-op Post-op

Dumping

GERD

Page 7: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Endoluminal Gastric Pouch Reduction

Endoluminal Gastric Pouch Reduction

3 patients underwent repeat procedure due to unsatisfactory results.

Maximum weight loss: 67 lbsPostprandial diarrhea/GERD resolved.

Slowed gastric emptyingObliteration of the gastrocolic reflexNew valve created just distal to GE junction

3 patients underwent repeat procedure due to unsatisfactory results.

Maximum weight loss: 67 lbsPostprandial diarrhea/GERD resolved.

Slowed gastric emptyingObliteration of the gastrocolic reflexNew valve created just distal to GE junction

Page 8: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Endoluminal Gastric Pouch Reduction

Endoluminal Gastric Pouch Reduction

Mechanism of Weight loss

Reduce size of gastric pouch

Possible to reduce size of stoma

Reduce compliance in the gastric pouch

Slows gastric emptying

Mechanism of Weight loss

Reduce size of gastric pouch

Possible to reduce size of stoma

Reduce compliance in the gastric pouch

Slows gastric emptying

Page 9: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Endoluminal Gastric Pouch Reduction

Endoluminal Gastric Pouch Reduction

Pre anastomosis Post anastomosis

Page 10: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Endoluminal Gastric Pouch Reduction

Endoluminal Gastric Pouch Reduction

Gastro-esophageal junction and gastric pouch

Page 11: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

Lessons LearnedLessons Learned

Reduce anastomotic diameterGross pouch dilation difficult to

completely remediateDumping and GERD symptoms do

improve.Double fastener techniqueWeight loss is modestProcedure is safe.

Reduce anastomotic diameterGross pouch dilation difficult to

completely remediateDumping and GERD symptoms do

improve.Double fastener techniqueWeight loss is modestProcedure is safe.

Page 12: Second SLS presentation from Beth Israel

Society of Laparoendoscopic Surgeons 2009

THANK YOUTHANK YOU