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analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with n’-methylanthraniloyl-substituted purine and pyrimidine 39,59-cyclic nucleotides…
distinctive anatomical patterns of gene expression for cgmp-inhibited cyclic nucleotide phosphodiesterases rickey r reinhardt edward chin jian zhou masato taira* taku murata*…
j biomedical science and engineering 2013 6 73-84 jbise http:dxdoiorg104236jbise201365a011 published online may 2013 http:wwwscirporgjournaljbise cyclic nucleotide phosphodiesterase…
lund university po box 117 221 00 lund +46 46-222 00 00 expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. heimann, emilia…
pdestrian: pde structure and ligand interaction annotated database chapter 2 chimed jansen, albert j. kooistra, iwan j. p. de esch, rob leurs and chris de graaf manuscript…
biological and structural characterization of trypanosoma cruzi phosphodiesterase c and implications for design of parasite selective inhibitors*□s received for publication,…
efficient integration of myriad extracellular and intra- cellular signals is required to maintain adaptive cellular functioning dysregulation of this integration promotes…
thorax 199146:512-523 new drugs review phosphodiesterase inhibitors: new opportunities for the treatment of asthma theodore j torphy bradley j undem theophylline has been…
a cytogenetic analysis of cyclic nucleotide phosphodiesterase activities in drosophila john a. kiger, jr., and eric gclanty department of genetics, university of california,…
minireview properties and functions of gaf domains in cyclic nucleotide phosphodiesterases and other proteins roya zoraghi jackie d corbin and sharron h francis department…
structure, vol. 12, 2233–2247, december, 2004, ©2004 elsevier ltd. all rights reserved. doi 10.1016/j.str.2004.10.004 structural basis for the activity of drugs that inhibit…
two novel photoactivatable phosphodiesterases to independently hydrolyze camp and cgmp by fiona bergin a thesis submitted in conformity with the requirements for the degree…
university of groningen phosphodiesterases as therapeutic targets for respiratory diseases zuo, haoxiao cattani-cavalieri, isabella musheshe, nshunge nikolaev, viacheslav…
nucleotide sequence specificity of restriction endonucleases nobel lecture, 8 december, 1978 by hamilton o. smith department of microbiology, the johns hopkins university…
application form germline brca mutation testing to determine eligibility for talazoparib treatment in patients with locally advanced or metastatic her2-negative breast cancer…
no slide title nucleotide metabolism 1 nucleotide nucleoside 2 3 4 a key molecule in purine and pyrimidine biosynthesis 5 fig 22-32 purines: where does all them darn atoms…
vol. 13, no. 10molecular and cellular biology, oct. 1993, p. 6558-6571 0270-7306/93/106558-14$02.00/0 copyright © 1993, american society for microbiology a family of human…
microsoft word - 8823156-file00membrane camp oscillations and pulsatile insulin secretion geng tian1, jenny sågetorp1, yunjian xu1, hongyan shuai1, eva degerman2 and
1 title: activity-specificity trade-off gives pi5p4kβ a nucleotide preference to function as a gtp- sensing kinase authors koh takeuchi1*# yoshiki ikeda211# miki senda3#…
22 a multi-targeted antisense oligonucleotide-based therapy directed at phosphodiesterases 4 and 7 for copd rosanne seguin and nicolay ferrari topigen pharmaceuticals inc.,…