Scientific BackgroundScientific Backgroundonon

CordyMaxCordyMax

Presented byJames M. Rippe, M.D.

Tufts University School of MedicineCenter for Clinical and Lifestyle ResearchPharmanex Institute for Cardiovascular

Health and Sports Nutrition

Cordymax Cs-4Cordymax Cs-4The natural way to overcome

recurring fatigue

Wild Cordyceps sinensisWild Cordyceps sinensis

Parasitic mushroom found in high altitudes

What is CordyMax?What is CordyMax?

Exclusive clinically proven formulation Unique fermentation process Standardized to adenosine and

mannitol 15 years of research; over 36 studies Unlike wild harvested cordyceps, not

dependent on anecdotal data for efficacy

CordyMax BenefitsCordyMax Benefits

Improves oxygen consumption Provides for more robust lung function Supports greater natural resistance Reduces symptoms of fatigue Increases vitality

CordyMaxCordyMax Cs-4 Cs-4Competitive PositioningCompetitive Positioning

Quality of Life(Overcome Fatigue)

Athletic Performance(Enhancement)

Age

Younger

Older

CordyMaxCs-4

Ginsana

Clinical use of CordyMaxClinical use of CordyMax

>1800 patients with a variety of diseases involved in CordyMax clinical trials in China

# of trials• Pulmonary function 20• Cardiovascular function 4• Free radical scavenging 4• Anti-fatigue 2

Anti-fatigue effect confirmed in placebo, double-blind study designed by Dr. C. Cooper (UCLA)

(Presented at American Academy of Sports Medicine)

Clinical Trials for CordyMax Clinical Trials for CordyMax

1.4

1.6

1.8

2.0

2.2

CordyMax Placebo

Oxy

gen

(L

/min

) Pretreatment

At Week 6+6.69%

-0.05%

Cordymax Increases Oxygen Cordymax Increases Oxygen Intake by the LungsIntake by the Lungs

+12.6%

0.8

0.9

1.0

1.1

1.2

1.3

1.4

CordyMax Placebo

(L/m

in)

-2.40%

Pretreatment

At Week 6

Better tolerance during Better tolerance during anaerobic conditionsanaerobic conditions

Effect of CordyMax on Effect of CordyMax on Asthenia in Elderly PeopleAsthenia in Elderly People A placebo controlled clinical trial A total of 59 elderly asthenia people 33 people were treated with

CordyMax™for 3 months

Symptom

Intolerantto cold

Dizziness

Tiredness

Tinnitus

CordyMax

CordyMax

CordyMax

CordyMax

group

control

control

control

control

n

28

20

24

23

26

27

14

15

VeryEffective

(n)

19

0

19

2

21

0

1

2

Effective

(n)

5

1

1

4

3

4

10

2

NotEffective

(n)

4

19

4

17

2

23

3

11

TotalEffective

Rate

89.3%

5%

83.3%

26%

92.3%

14.3%

78.5%

25.6%

Improvement in elderly subjectsImprovement in elderly subjectsafter CordyMax after 3 monthsafter CordyMax after 3 months

Randomized double blind Randomized double blind study on endurance in 200 study on endurance in 200 sedentary individualssedentary individuals James Rippe, MD et al.

Center for Clinical and Lifestyle Research and

Pharmanex Institute for Cardiovascular Health and Sports nutrition

CordyMax Cs-4…CordyMax Cs-4…Not Just Another GinsengNot Just Another Ginseng

CordyMax

Recurring fatigue

Gentle, mild non-stimulant

No adverse effect on blood pressure

Long term use appropriate

Secondary benefits

P. Ginseng

Athletes

Stimulating

Contraindicated in high blood pressure

Long term use not recommended

PharmanexPharmanex Institute Instituteforfor

Cardiovascular Health and SportsCardiovascular Health and SportsNutritionNutrition

PharmanexPharmanex Institute Institute

Peer reviewed science Education Public communication