ICRS Getting Social – Join us

We are pleased to announce that the ICRS has been establishing its Social Media presence on the major platforms during last few months. For those of you who are active on these platforms, we strongly encourage you to CONNECT, ENGAGE & SHARE - Be the ICRS Digital Ambassadors Worldwide!

We all are looking forward to welcoming you at upcoming the ICRS 11th World Congress. Don’t forget to use hash tag: #ICRS2013 on these Social Media sites if you are talking about this meeting (Twitter, Facebook, LinkedIn and Google+ all support hash# tagging to help categorizing and organize topics).

The ICRS aims to leverage the rapidly advancing digital technologies continuously to help the society stay engaged, transparent and informative for all of our stakeholders. By the way, we will launch ICRS Blog and maybe ICRS Chatter app. Stay tuned.

Best regards,

Your ICRS Cartilage Executive Office Team

Scan the QR* (Quick Response) code with your QR reader or Click the icon (Digital Copy), you will be taking to the corresponding ICRS Social Media site directly.

Video: Social Media 2013

ICRS Getting Social – Join us

We are pleased to announce that the ICRS has been establishing its Social Media presence on the major platforms during last few months. For those of you who are active on these platforms, we strongly encourage you to CONNECT, ENGAGE & SHARE - Be the ICRS Digital Ambassadors Worldwide!

We all are looking forward to welcoming you at upcoming the ICRS 11th World Congress. Don’t forget to use hash tag: #ICRS2013 on these Social Media sites if you are talking about this meeting (Twitter, Facebook, LinkedIn and Google+ all support hash# tagging to help categorizing and organize topics).

The ICRS aims to leverage the rapidly advancing digital technologies continuously to help the society stay engaged, transparent and informative for all of our stakeholders. By the way, we will launch ICRS Blog and maybe ICRS Chatter app. Stay tuned.

Best regards,

Your ICRS Cartilage Executive Office Team

Scan the QR* (Quick Response) code with your QR reader or Click the icon (Digital Copy), you will be taking to the corresponding ICRS Social Media site directly.

Video: Social Media 2013

ICRS Getting Social – Join us

We are pleased to announce that the ICRS has been establishing its Social Media presence on the major platforms during last few months. For those of you who are active on these platforms, we strongly encourage you to CONNECT, ENGAGE & SHARE - Be the ICRS Digital Ambassadors Worldwide!

We all are looking forward to welcoming you at upcoming the ICRS 11th World Congress. Don’t forget to use hash tag: #ICRS2013 on these Social Media sites if you are talking about this meeting (Twitter, Facebook, LinkedIn and Google+ all support hash# tagging to help categorizing and organize topics).

The ICRS aims to leverage the rapidly advancing digital technologies continuously to help the society stay engaged, transparent and informative for all of our stakeholders. By the way, we will launch ICRS Blog and maybe ICRS Chatter app. Stay tuned.

Best regards,

Your ICRS Cartilage Executive Office Team

Scan the QR* (Quick Response) code with your QR reader or Click the icon (Digital Copy), you will be taking to the corresponding ICRS Social Media site directly.

Video: Social Media 2013

ICRS Getting Social – Join us

We are pleased to announce that the ICRS has been establishing its Social Media presence on the major platforms during last few months. For those of you who are active on these platforms, we strongly encourage you to CONNECT, ENGAGE & SHARE - Be the ICRS Digital Ambassadors Worldwide!

We all are looking forward to welcoming you at upcoming the ICRS 11th World Congress. Don’t forget to use hash tag: #ICRS2013 on these Social Media sites if you are talking about this meeting (Twitter, Facebook, LinkedIn and Google+ all support hash# tagging to help categorizing and organize topics).

The ICRS aims to leverage the rapidly advancing digital technologies continuously to help the society stay engaged, transparent and informative for all of our stakeholders. By the way, we will launch ICRS Blog and maybe ICRS Chatter app. Stay tuned.

Best regards,

Your ICRS Cartilage Executive Office Team

Scan the QR* (Quick Response) code with your QR reader or Click the icon (Digital Copy), you will be taking to the corresponding ICRS Social Media site directly.

Video: Social Media 2013

Social Media – Follow us on:

Registration & Fees / Preços & InscriçõesRegistration online only through www.cartilage.orgInscricões serão aceitas somente online via www.cartilage.org

Fees apply in Euros Nov 15, 2018 Nov 16–Jan 31 From Feb 01, 2019 Early Fee Late Fee Onsite Fee

Residents/Students & Euros 80.00* Euros 130.00* Euros 180.00*Physiotherapists* BR$ 360.00* BR$ 585.00* BR$ 810.00*

ICRS Members Euros 150.00 Euros 180.00 Euros 220.00 BR$ 675.00 BR$ 810.00 BR$ 990.00

SBCJ Members** Euros 180.00** Euros 220.00** Euros 250.00** BR$ 810.00** BR$ 990.00** BR$ 1125.00**

Non-Members Euros 200.00 Euros 250.00 Euros 280.00 BR$ 900.00 BR$ 1125.00 BR$ 1260.00

Optional Wet-Lab* Euros 300.00*** Euros 350.00*** Euros 400.00***1⁄2 day Hands-on course BR$ 1250.00* BR$ 1575.00* BR$ 1800.00*

*Resident Status to be accompanied by certifi cate signed by the head of department / somente accompanhado de um certifi cado da instituição, assindado pelo chefe do departamento

**SBCJ Membership Certifi cate to be sent / SBCJ Certifi cado a ser enviado para offi ce@cartilage.org ***Wet Lab at SP University on 12.02.2019 (limited to 18 vacancies, 18 vagas disponiveis)

Pagamento: Atenção: Os preços em BR$ são somente referenciais (Junho 2018). Os valores sao cobrados em Euro e serão convertidos em Reais pela taxa de cambio do dia de pagamento, pela sua administradora do cartão de credito. Os pagamentos poderão ser effetivados somente com cartões de credito internationais.

Included in the Registration Fee / Incluído na Inscrição• Access to all Scientifi c Sessions and Industry Exhibition• 3 Coffee Breaks / 3 Intervalo de Café• 1 Lunch / 1 Almoço• Registration Material

Cancellation of Registrations / Cancelamento de Inscrições• Refund on cancellations until Nov 15, 2018 80% of refund• Refund on cancellations until Jan 15, 2019 50% of refund• Refund on cancellations after Jan 15, 2019 no refund is possible

• Restituição de cancelamentos até Nov. 15, 2018 80% de reembolso• Restituição de cancelamentos até Jan. 15, 2019 50% de reembolso• Restituição de cancelamentos apos Jan. 15, 2019 não será possível a restituição

Important Dates / Datas ImportantesPlease mark the following dates in your agenda:Por favor anotem as seguintes datas na sua agenda:

Nov 15, 2018 Deadline Course Registration at highly reduced fee Data limite para inscrição com taxa reduzida

Jan 15, 2019 Deadline for Cancellation of Congress Registration (refund 50%) Data limite para cancelamento da Inscrição no Congresso com 50% de restituição

Feb 01, 2019 Deadline Congress Registration at Late Fee Data limite para Inscrição no Congresso com valor completo

Course Language / IdiomaPortuguese / English, Simultaneous translation is available

Accommodation / Accommodação Participants are requested to book their hotel arrangement directly with the Hotel Maksoud SP or through our website.

Os participantes poderão effetuar a sua reserve de Hotel com preços bem especiais diretamente com o Hotel Maksoud (mentionar Evento ICRS 2019). Os preços das diárias especiais accordados são: BR$ 405.00 Sgl e BR$ 440.00 / Dbl + Taxas, (incluido Café de Manha)

Hotel ReservationsEmail: maksoud@maksoud.com.br Group Event: ICRS 2019

Website: www.accorhotels.com Promotional Code: SPECI

Organisation / OrganizaçãoInternational Cartilage Regeneration & Joint Preservation Society – ICRSCom apoio: SBOT, SBCJ

Intl. Faculty / Palestrantes InternacionaisWilliam Bugbee, USA Tom Minas, USA Jack Farr, USA Sabrina Strickland, USAAndreas Gomoll, USA Ken Zaslav, USAChristian Lüring (DE)

Local Committee / Diretores LocaisCamila Kaleka Cohen (BR) Marco Demange (BR)Luis Eduardo Passarelli Tirico (BR) Moisés Cohen (BR)

Organizing Offi ce/ OrganizaçãoCartilage Executive Offi ce GmbHMr. Stephan SeilerSpitalstrasse 1908623 Wetzikon, SwitzerlandPhone: +41 (44) 503 73 70Fax: +41 (44) 503 73 72Email: sseiler@cartilage.org

Venue / LocalMaksoud PlazaRua São Carlos do Pinhal, 424 01333.000 - São Paulo / SP reservas/booking: 0800 13 44 11 www.maksoud.com

ICRS on the InternetVisit our website at www.cartilage.org Information about the event are permanently updated and will provide online registration. For updated information on the programme (topics, faculty, registration fees, etc.) please visit our website www.cartilage.org

Visite nosso site: www.cartilage.org Informações sobre o evento estão permanentemente atualizadas e vão permitir o registro on-line. Para informações atualizadas sobre o programa (Temas, corpo docente, inscrições, taxas, etc.) visite nosso site www.cartilage.org

Industry Support & Exhibition / Apoio da IndústríaOur Industry partners are cordially invited to contribute and to support this important event for profes-sionals and Brazilian key decision-makers in clinical cartilage repair. Small table top exhibition spaces and sponsorship opportunities will be available to expose and enhance your organization’s visibility. Basic and advanced education of Classical and cutting edge topics in Cartilage Repair and Cartilage Research are the themes of the congress. For more information, please contact the ICRS Offi ce at sseiler@cartilage.org or phone +41 44 390 1840

A indústria está convidada a contribuir e apoiar este evento importante para profi ssionais brasileiros e formadores de opiniões na área de reparo da cartilagem. Pequenos espaços de Exibição e oportuni-dades para patrocíneo estarão disponíveis para expor e aumentar a visibilidade de sua organização. Educação básica e avançada de tópicos clássicos e de ponta no Reparo da Cartilagem e Pesquisa em Cartilagem são os temas do Congresso. Para mais informação, por favor contactem o Escritório da ICRS (Sr. Stephan) pelo email sseiler@cartilage.org ou no telefone + 41 44 503-73 70.

Sponsors & Exhibitors

International Cartilage Regeneration& Joint Preservation Society

www.cartilage.org

ICRS World Series

São Paulo BrazilFebruary 07–08, 2019 Preliminary

Programme

#ICRSWORLDSERIES

Caros Colegas e Amigos, A cirurgia de reparo da cartilagem articular encontra-se em desenvolvimento no Brasil e na América Latina. Temos acessos a diversas técnicas, porém é senso comum que para as lesões de cartilagem grandes, há limitações e diferenças em relação a vários países do exterior, tornando o tratamento de grandes defeitos um desafio para o ortopedista. Com grande pra-zer, nós lhe convidamos para o Curso de Reparo de Lesões da Cartilagem Articular realizado sob égide da ICRS no Brasil. O curso acontecerá em São Paulo, no Hotel Maksoud Plaza, de 07 a 08 de fevereiro de 2019.

Pretendemos discutir e trocar experiência sobre o tratamento de lesões grandes da cartila-gem articular, com enfoque em soluções possíveis com as tecnologias existentes para uso clínico no Brasil. Teremos também aulas sobre novas tecnologias e perspectivas futuras no tratamento de lesões condrais e osteocondrais, mas o principal objetivo do curso é discutir soluções possíveis de serem realizadas no nosso meio. Consideramos este aspecto a maior diferença e o maior benefício para o ortopedista brasileiro em comparação a assistir eventos realizados no exterior.

Teremos também um dia de Cadaver Lab opcional no sábado dia 09 de fevereiro para um número limitado de 18 participantes, segundo ordem de inscrição. Por favor, visite o site www.cartilage.org para atualizações sobre o programa do curso e outras informações. Temos convicção que será um excelente curso!

Camila Kaleka Cohen, Moisés Cohen, Marco Demange, Luis Eduardo Passarelli TiricoComissão Organizadora

Dear Colleagues & Friends, The subspecialty of Cartilage repair is emerging in South America and especially in Brazil. We recognize that cartilage defects remain a challenge for orthopedic surgeons and their patients, especially for larger defects. It is a great pleasure to invite you to the ICRS Course in Brazil, which will be held in São Paulo from February 07 to 08, 2019 at the Maksoud Plaza Hotel.

We intend to discuss and exchange experience regarding the treatment of large cartilage de-fects considering technology that is available for clinical use in Brazil. Although there will be lectures discussing future trends and novel treatments of cartilage defects, the primary aim of this course is to present practical solutions currently available to our surgeons. We feel this will be the most important benefit of our course comparing to attending meetings abroad.

We are also having an optional Hands-On Cadaver Lab of Saturday February 09 for a limited number of 18 attendees. Please visit the website www.cartilage.org for updates in our course program and other information. It is going to be a great course!

Camila Kaleka Cohen, Moisés Cohen, Marco Demange, Luis Eduardo Passarelli TiricoOrganizing Committee

PRELIMINARY PROGRAMMEPRELIMINARY PROGRAMMEWELCOME / BEMVINDOS PRELIMINARY PROGRAMMEThursday, February 07, 2019Module 1 Basic Science and Imaging in Cartilage Defects Ciência Básica e Imagem em Lesões Condrais Moderator: Moises Cohen (BR)13:00 – 13:10 Welcome and Introduction – Moises Cohen (BR) Boas Vindas e Introdução13:10 – 13:20 Clinically relevant aspects of structure & biomechanics of articular cartilage – Camila Cohen (BR) Aspectos clinicamente relevantes da estrutura e biomecânica da cartilagem articular13:20 – 13:30 Imaging on Chondral and Osteochondral Lesions – Abdalla Skaf (BR) Avaliação por imagem das lesões condrais e osteocondrais 13:30 – 13:40 Cartilage Markers – Eliane Antoniolli (BR) Marcadores de lesão condral e reparo13:40 – 13:50 Treatment Algorithms and Evidence based evaluation of surgical cartilage repair techniques Evidência da literatura para as técnicas de reparo articular – Andreas Gomoll (USA)

Module 2 PRP, Cytokines, & Hyaluronic Acid PRP, Citocinas e Ácido Hialurônico Moderator: Luis Tirico (BR)14:00 – 14:10 PRP and PRF – How to prepare in the lab and in the clinical practice. Conventional centrifuges, closed system centrifuges and apheresis – Adriano Almeida (BR) PRP e PRF – Como preparar no laboratório e na prática clínica. Centrífugas convencionais, sistemas fechados e aférese14:10 – 14:20 Basic Science and Differences among Hyaluronic Acid – Márcia Uchoa (BR) Ciência Básica e Diferenças entre Ácidos Hialurônicos14:20 – 14:30 Clinical Evidence in the Use of PRP & Hyaluronic Acid for cartilage defects and early OA Evidencias clinicas no uso do PRP & Ac Hialuronico nas lesões da cartilagem – G. Constantino (BR)14:30 – 14:40 Genicular Nerve Block: Clinical Evidence and Clinical Results – Marcelo Krause (BR) Bloqueio do Nervo Genicular: Evidência Atual e Resultado Clínico

Module 3 Microfracture, Autologous Osteochondral Transplant & Mosaicplasty Microfratura, Transferência Osteocondral Autóloga & Mosaicoplastia Moderator: Moises Cohen (BR)14:50 – 15:00 Basic Science Behind Scaffolds – Marco Demange (BR) Ciência básica sobre Scaffolds15:00 – 15:10 Microfracture & AMIC – Surgical Technique: Tips and Pearls – Moises Cohen (BR) Microfratura e AMIC – Aspectos técnico-cirúrgicos do procedimento15:10 – 15:20 Biomaterials for Enhanced MFX – Christian Lüring (DE) Biomaterials for the Treatment of Cartilage Defects with Matrix-augmented Bone Marrow Stimulation Technique - Technique & Literature – Christian Lüring (DE)

15:40 – 16:10 Coffee Break / Exhibition

16:10 – 16:20 OATS, COR, Multiple plugs mosaicplasty Surgical Technique: Tips and Pearls – Luis Tirico (BR) OATS, COR, Mosaicoplastia com múltiplos cilíndros Técnica cirúrgica e dicas16:20 – 16:30 Imaging on Microfracture Repair and Mosaicplasty Repair MOCART SCORE and what to look for? – Conrado Cavalcanti (BR) Avaliação por imagem do reparo de microfraturas e do reparo de mosaicoplastia: O que procurar e escore MOCART?16:30 – 16:40 Rehabilitation, Return to Sports, Expected Short & Long-term Results – Rafael Tambassi (BR) after Microfracture & Autologous Osteochondral Transplantation Reabilitação, retorno ao esporte e resultados de curto e long prazo esperados após

Microfratura e Transplante Autólogo OsteocondralModule 4 Osteotomy / Osteotomia Moderator: Marco Demange (BR)17:00 – 17:10 Long Limb Axis Evaluation, Patellofemoral Joint Evaluation & Osteotomy Planning Avaliação do eixo mecânico, avaliação da articulação patelo femoral e planejamento da osteotomia – Tom Minas, (US)17:10 – 17:20 Valgus Tibial Osteotomy – Surgical Technique: Tips and Pearls – Andreas Gomoll (USA) Osteotomia Valgizante da Tíbia – Aspectos cirúrgicos17:20 – 17:30 Varus Femoral Osteotomy – Surgical Technique: Tips and Pearls – Bill Bugbee (USA) Osteotomia Varizante do Fêmur – Aspectos cirúrgicos17:30 – 17:40 Patellofemoral Joint Osteotomy & Simple Trochleoplasty: Tips and Pearls – Jack Farr (USA) Osteotomias na Articulação Patelofemoral e Trochleoplastia (Ressecção de Bump)

Module 5 Case Discussions / Discussão de Casos Debridamento, Microfratura, Transferência Osteocondral & Osteotomia Moderator: Moises Cohen (BR)18:00 – 18:50 Clinical Cases of Simple and Complex Chondral and Osteochondral Lesions Casos Clínicos de Lesões Condrais e Osteocondrais Simples e Complexas18:50 – 19:00 Take Home Points Marco Demange (BR)

Friday, February 8, 201907:45 – 08:00 Highlights & Take Home Points from Day 1 – Marco Demange (BR) Aspectos importantes no tratamento de lesões condrais, osteocondrais e meniscais

Module 6 Meniscus Repair, Transplant & Substitutes Reparo Meniscal, Transplante de Menisco e Substitutos Meniscais Moderator: Camila Cohen (BR)08:00 – 08:10 Imaging Evaluation of Meniscal Tear and Repair – Laércio Rosemberg (BR) Avaliação por Imagem da Lesão Meniscal e Reparo 08:10 – 08:20 In-Side Out, All-Inside and Out-Side In Meniscal Suture Surgical Technique: Tips and Pearls Sutura Meniscal de Dentro para Fora e Fora para Dentro-Técnica Cirúrgica – Luis Tirico (BR)08:20 – 08:30 Meniscal Root Repair and Ramp Lesion – Moises Cohen (BR) Lesão de Raiz Meniscal e Lesão em Rampa08:30 – 08:40 Meniscal Transplant – Surgical Technique: Tips and Pearls – Jack Farr (USA) Transplante Meniscal: Técnica Cirúrgica08:40 – 08:50 Meniscal Substitutes, Implants and Future Trends – Camila Cohen (BR) Substitutos Meniscais, Implantes e Tendências Futuras

Module 7 Fresh Osteochondral Transplantation Transplante Osteocondral a Fresco Moderator: Luis Tirico (BR)09:00 – 09:10 Historical Development & Basic Science behind Fresh Osteochondral Transplantation Guilherme Gracitelli (BR) História do desenvolvimento e Ciência Básica do Transplante Osteocondral à Fresco09:10 – 09:20 Fresh Osteochondral Allograft – Surgical Technique: Tips & Pearls – Bill Bugbee (USA) Transplante Osteocondral-Aspectos técnico-cirúrgicos do procedimento09:20 – 09:30 Clinical Indications, Rehabilitation, Return to Sports Expected short and long-term results – L. Tirico (BR) Indicações, Reabilitação, retorno ao esporte e resultados de curto e long prazo esperados

Module 8 Case Discussions / Discussão de Casos Meniscus Repair, Transplant & Substitutes Moderator: Luis Tirico (BR)09:40 – 10:30 Clinical Cases – Meniscus Repair, Transplant and Substitutes What to do with and without Osteochondral Allograft available? Casos Clínicos – Reparo meniscal, transplante meniscal e substitutos e o que fazer na disponibilidade ou na ausência de Trasplante Osteocondral?

10:30 – 11:00 Coffee Break / Exhibition

Module 9 Cell Therapy: Autologous Chondrocyte Implantation (ACI) Terapia Celular: Transplante Autólogo de Condrócitos Moderator: Moises Cohen (BR)11:00 – 11:10 From ACI to MACI: Cell Transplantation for Cartilage Repair – Ken Zaslav (USA) História do desenvolvimento do IAC ao MACI: Transplante Celular para Reparo Condral11:10 – 11:20 ACI – Surgical Technique: Tips & Pearls – Tom Minas, (US) Implante Autólogo de Condrócitos (IAC) – Aspectos técnico-cirúrgicos do procedimento 11:20 – 11:30 ACI in the Patellofemoral Joint – Clinical Evidence – Sabrina Strickland (USA) IAC na Articulação Femoro-Patelar – Evidência Clínica11:30 – 11:40 ACI Rehabilitation & Return to Sports Expected short and long-term Results – Andreas Gomoll (USA) Reabilitação, retorno ao esporte e resultados de curto e long prazo esperados IACModule 10 Case Discussions / Discussão de Casos Cell Therapy / ACI Moderator: Marco Demange (BR)12:00 – 13:00 Clinical Cases – What to do with and without cell therapy available? Casos Clínicos – O que fazer na disponibilidade ou ausência de terapia celular?

13:00 – 14:30 Lunch Break / Almoço – Visita aos Estandes

Module 11: Stem Cells & Cartilage Fragments in Cartilage Repair Células Tronco e Fragmentos de Cartilagem no Reparo de Lesão Condral14:30 – 14:40 Stem Cells and Adult Mesenchymal Pluripotent Cells – Basic Science – Moises Cohen (BR) Células Tronco e Células Pluripotente Mesenquimais Adultas 14:40 – 14:50 Bone Marrow Derived MSC (BMAC) – Clinical Application – Marco Demange (BR) Células Mesenquimais de Medula Óssea (BMAC) – Aplicação Clínica14:50 – 15:00 Adipose-Derived MSC – Clinical Application – Camila Cohen (BR) Células Mesenquimais Derivada de Gordura – Aplicação Clínica15:00 – 15:10 Juvenile Cartilage Fragments and Minced Cartilage – Jack Farr (USA) Fragmentos de Cartilagem Juvenil e Cartilagem Fragmentada

15:30 – 16:00 Coffee Break / Exhibition

Module 12: Subchondral Bone and Unicompartimental Osteoarthritis Osso Subchondral e Osteoartrite Unicompartimental Moderator: Marco Demange16:00 – 16:10 Clinical Evidence on Subchondral Bone Lesions, Bone Edema & OA Progression – M. Bonadio (BR) Evidência Clínica de lesão do osso subcondral, edema ósseo e progressão para artrose16:10 – 16:20 Sub-chondral Bone Reconstruction in Cartilage Repair – Ken Zaslav (USA) Reconstrução do Osso Subcondral no Reparo da Cartilagem Articular16:20 – 16:30 Subchondroplasty: Basic Science and Surgical Procedure – Marco Demange (BR) Subcondroplastia: Ciência Básica e procedimento cirúrgico16:30 – 16:40 Tibio-Femoral Partial Arthroplasty – UKA – William Bugbee (USA) Artroplastia Tibio-femoral Parcial do Joelho – Prótese Unicompartimental 16:40 – 16:50 Partial Ressurfacing Knee Arthroplasty & Patellofemoral Arthroplasty Artroplastia de Recapeamento e Prótese Patelofemoral – Sabrina Strickland (USA)

Module 13 Case Discussions / Discussão de Casos Stem Cells, Subchondral Bone and Unicompartimental Arthritis Moderator: Marco Demange (BR)17:10 – 18:00 Casos Clínicos – Células Tronco, Osso Subcondral e Osteoartrose unicompartimental 18:00 – 18:10 Take Home Points

Saturday, Feb 09, 2019–08.00 – 12.00 Optional Hands-on Cadaver Wet Lab – HCFMUSP

Laboratörio de Artroscopia – Instituto de Ortopedia e Traumatologia Numero limitado de 18 participantes, segundo ordern de inscrigäo

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