s1 2014 p1 set 30 questions.pdf

STEP 1 REVIEW COURSE – Part 1, Set 30

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1. A 35-year-old man is seen in the office for his chronic, recurrent peptic ulcer disease. It has been refractory to conventional treatment with PPIs. Your attending mentions that this might be caused by a tumor. What type of tumor may be responsible for this condition? If this patient also presented with renal stones and signs of hypogonadism, what syndrome might you suspect? (FA13 p304) (FA14 p329) (R p782, 1162)

2. How is thyroid hormone made and stored? (SU14 p192) (Phys p907) (H p2913)


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3. A 49-year-old trauma patient comes into the ER unconscious and in need of surgery. What are the exceptions to informed consent? (FA13 p56) (FA14 p59) (SU14 p23-24)

4. What is the role of clomiphene in the treatment of PCOS? What is the mechanism of action of clomiphene? (FA13 p540) (FA14 p590) (SU14 p226)


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5. Ceftriaxone is used for the treatment of sexually-transmitted N. gonorrhea infections. What generation of cephalosporin is ceftriaxone? Which generation of cephalosporins is effective against Pseudomonas? Are cephalosporins bacteriostatic or bactericidal? (FA13 p178) (FA14 p181) (SU14 p350-351)

6. What are the side effects of amiodarone, and what testing should be performed periodically on patients taking it? (FA13 p284) (FA14 p303) (SU14 p74-75)


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7. A patient is undergoing treatment with recombinant interferon for his Hepatitis C. In what ways do interferons interfere with viral protein synthesis? (FA13 p201) (FA14 p205-206) (SU14 p265)

8. A 35-year-old white woman presents with a dull ache in her jaw that is made worse by chewing. She states that this pain corresponds to her recent promotion and increase in responsibilities. What is the most likely diagnosis? (H p269)


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9. In regard to seizures, what do the terms partial, generalized, simple and complex mean? (FA13 p445) (FA14 p485) (SU14 p46)

10. Your patient develops a cough with the new antihypertensive drug you prescribed her. What are some other side effects associated with this medication? (FA13 p502) (FA14 p549) (SU14 p78-79, 86)

*Page references are as follows: FA13: First Aid for the USMLE Step 1 2013 FA14: First Aid for the USMLE Step 1 2014 SU14: Step-Up to USMLE Step 1 2014 R: Robbins and Cotran Pathologic Basis of Disease, 8th ed. (2010) Phys: Guyton and Hall Textbook of Medical Physiology, 12th ed. (2011) H: Harrison’s Principles of Internal Medicine, 18th ed. (2012) COA: Clinically Oriented Anatomy, 6th ed. (2010) GG: Goodman and Gilman Pharmacological Basis of Therapeutics, 12th ed. (2011)

s1 2014 p1 set 30 questions.pdf

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