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Rl f Bi ft R oles of Biosaf et Reduction at Hum International Federation of 15 – 18 February 2011, Ban Em Emergency Centre for Transboundary Animal Diseases for Asia and the Pac AGATCE Food and Agriculture Organization of the United Nations t & Bi it i Ri k ty & Biosecurity in Risk manAnimal Interface Biosafety Association Conference ngkok, Thailand Pawin Padungtod DVM, PhD Pawin Padungtod DVM, PhD Regional Project Coordinator mergency Center for Transboundary Animal Diseases (ECTAD) Regional Office for Asia and the Pacific cific ECTAD RAP 1

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R l f Bi f tRoles of BiosafetReduction at HumInternational Federation of 15 – 18 February 2011, Ban

Em

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

t & Bi it i Ri kty & Biosecurity in Risk man‐Animal InterfaceBiosafety Association Conference

ngkok, Thailand

Pawin Padungtod DVM, PhDPawin Padungtod DVM, PhDRegional Project Coordinator 

mergency Center for Transboundary Animal Diseases (ECTAD)Regional Office for Asia and the Pacific

cific ECTAD ‐ RAP

1

Acknowledgement

N ti l A th iti• National Authorities• International Partners• FAO Field Officers

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

cific ECTAD ‐ RAP

2

FAO Food and AgrFAO – Food and AgrOrganization of the g• Core Activities

– AgricultureAgriculture– Economic and Social Development– Fisheries and Aquaculture

Forestry– Forestry– Natural Resources– Technical Cooperation

R i l Offi• Regional Offices– Chile, Egypt, Ghana, Hungary and T

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

icultureiculture United Nation

Thailand

cific ECTAD ‐ RAP

3

www.fao.org

ECTAD – EmergencECTAD  EmergencTransboundary Any• Established in 2004 in response 

to HPAI crisisto HPAI crisis– 2005 ECTAD‐RAP, Bangkok

– 2007 ECTAD Sub‐Regional, KathmanduKathmandu

• Human – Animal Interface

• Livelihood

• EIDs and TADs– Zoonoses : HPAI, H1N1, Rabies, 

B ll iBrucellosis

‐ Animal Specific Diseases : FMD, CSF, PRRS 

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

cy Center forcy Center for imal Diseases

cific ECTAD ‐ RAP

4

FAO Biosecurity

F• Foo

• Zoo

• Anim• Anim

• Plan

• LivinLivinProd

• Inva

• Env

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

d S f td Safety

noses

mal Healthmal Health

nt Health

ng Modified Organisms andng Modified Organisms and ducts

asive Alien Species

ironmental Protection

cific ECTAD ‐ RAP

5

f &Biosafety & BiosecuritRisk Reduction at Hum• Risk at Human – Animal Inte

• Biosafety & Biosecurity in LivBiosafety & Biosecurity in Liv

• Approaches to Risk Reductio

Highly Pathogenic Avian Influenza (HPAI)

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Highly Pathogenic Avian Influenza (HPAI)Feb 2010 – Feb 2011

Food and Agriculture Organization of the United Nations

ty in man‐Animal Interfacerface

vestock Productionvestock Production

on under One‐Health Concept

cific ECTAD ‐ RAP

6

Ri k t H A iRisk at Human‐Anima

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

(Daszek, 2000)

Food and Agriculture Organization of the United Nations

l I t fal Interface

• By 2020, the demand for animal protein will 

i 30 billirequire over 30 billion animals 

cific ECTAD ‐ RAP

7

Encroachment of Wild

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

dlife Habitat

Spill over of pathogens– Direct contact

– Vector

– Food

Spill back– Direct contactDirect contact

– Waste

– FomiteFomite

cific ECTAD ‐ RAP

8

d i kModern Livestock Pro

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

d ioduction

Intensive Agriculture– Pathogen amplification

– Virulence characteristic

– Increase density/contact

cific ECTAD ‐ RAP

9

Livestock ProductioLong distanceTransportation

Carrier

Worker/visit

Fertilizer

n Farms

ContaminatedWaste

Amplificationhost

Vector Carriertor

10

Li Bi d M kLive Bird Markets

Mi i th f i• Mixing pathogens from vario– Sources

Species– Species

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

ous

cific ECTAD ‐ RAP

11

Livestock & ZoonosesLivestock & ZoonosesRisk Reduction

1

22

3

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

(Philippe Ankers, FAO – AGAH)

Food and Agriculture Organization of the United Nations

PandemicPandemic 

1. Find disease fast– Public awareness – Reporting– Tracing backward and forward– Surveillance

2 C ll q ickl and h manel2. Cull quickly and humanely– Culling of susceptible stock on infected 

premises– Culling of susceptible stock on high riskCulling of susceptible stock on high risk 

premises (“dangerous contacts”)– Equitable Compensation

3. Stop the disease spreadingp p g– International movement control– National movement control– Vaccination 

i i

cific ECTAD ‐ RAP

– Biosecurity12

Biosecurity in Livestoc

• A–

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE(Philippe Ankers, FAO – AGAH)

Food and Agriculture Organization of the United Nations

ck Production

ll measures to minimize:– the risk of incursion of pathogensthe risk of incursion of pathogens 

into individual production units (bioexclusion)

– the risk of outward transmission (biocontainment)

the risk of onward transmission– the risk of onward transmission through the production and marketing chain.

cific ECTAD ‐ RAP

13

Th St f BiThree Steps of BiosecuProduction• Segregation

– Prevent contamination– Most important and effective stepMost important and effective step. 

strongest form of biosecurity and wshould be placed if at all possible

• Cleaning– Remove contamination– If all dirt is removed, there is little le

virus to be carried byf• Disinfection

– Kill any remaining virus– Important but is the least reliable st

biosecurity It’s effectiveness depenbiosecurity. It’s effectiveness depenmany factors, in particular the qualicleaning process

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE(Yoni Segal, FAO – AGAH)

Food and Agriculture Organization of the United Nations

it i Li t kurity in Livestock 

It is theIt is the where effort 

eft for the 

tep of nds onnds on ity of the 

cific ECTAD ‐ RAP

14

Bi it f PBiosecurity for PrevenHPAI and EIDs

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE(Yoni Segal, FAO – AGAH)

Food and Agriculture Organization of the United Nations

ti d C t l fntion and Control of 

Biosecurity and hygiene improvement of: – Live Bird Markets (LBM)

– Collection yards

Poultry transportation– Poultry transportation 

– Small scale poultry production farms

cific ECTAD ‐ RAP

15

ONE – HEALTH Concep

The discand

Humanand of henvi

Health

AnimalHealth

Environ‐mentalHealthHealth Health

(Lonnie King, 2008)

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

pt

collaborative effort of multiple iplines – working locally, nationally globally to attain optimal healthglobally – to attain optimal health umans, animals and our ironment

cific ECTAD ‐ RAP

16

Strategic Framework for ReStrategic Framework for ReDiseases at Animal‐Human‐

• Enem

• Strhe

Eff• Eff

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

educing Risks of Infectiouseducing Risks of Infectious ‐Ecosystems Interface

hanced disease surveillance and mergency response

rong and stable public and animal alth services

f ti i ti t t ifective communication strategies

cific ECTAD ‐ RAP

17

FAO‐OIE‐WHO Collabo

Sharicoordaddreaddreaniminterf

oration

ng responsibilities and dinating global activities to ess health risks at theess health risks at the al‐human‐ecosystems faces.

18

Global Laboratory Net

• A Global Cooperative Network– To rapidly diagnose normative disea

authorities responsible for reportinauthorities responsible for reportinepidemiologic events (GLEWS, EMP

– To support a country's full capabilitdi t OIEdiseases to OIE

– Investigate events of potential interreporting as required by the WHO I

twork

ases and emerging pathogens and inform ng on animal diseases and unusualng on animal diseases and unusual PRESi)

ty to report listed and emerging animal 

rnational public health concern for International Health Regulations (IHR)

19

Emerging Pandemic Th

Early identification of and response to dangcan become significant th

PREDICT RESPONDTo strengthen countries' capacity

To implement an early warning countries capacity

to identify and respond to new disease outbreaks in

i k d

early warning system that addresses the role of wildlife in f ilit ti th a quick and

sustainable mannerfacilitating the emergence and spread of new diseases

hreat Program (EPT)

gerous pathogens in animals before they reats to human health

IDENTIFY PREVENTTo support the development of

To build a behavior-change response todevelopment of

laboratory networks and strengthen diagnostic capacities in those areas th ht t lik l t b

change response to infectious diseases and support efforts to characterize high-i k ti th tthought most likely to be

the source of emerging diseases

risk practices that increase the potential for spreading such didiseases

200

Laboratory Network A

• Technical Capacity Building– Strategically developing overall net

assessment with standardized laboassessment with standardized labo

Overall Functionality of Animal Health Laboratories

In SE Asia(Anja Globig FLI)(Anja Globig, FLI) 

Activities

work capacity based on targeted ratory assessment toolsratory assessment tools

21

Laboratory Network A

• Development of Guidance, Polic– Joint international guidelines and st

l d l d– Develop SOPs, guidance, policy and

Activities

cy and Trainingtandards

d hd training consistent with ONE – HEALTH 

22

Laboratory Network A

• Laboratory Quality Systems– Biosafety & Biosecurity

l– Quality Assurance

Activities

23

Laboratory Network A

• Laboratory Networking– Support existing networks

• Global Early Warning System (GLEWS)

• Joint FAO/OIE Network of Expertise for

• Global Foodborne Infection Network (G

• Emerging and Dangerous Pathogens La

– Support networks for identificationanimals and humans

– Develop FAO/OIE/WHO laboratory 

Activities

r Animal Influenza (OFFLU)

GFN)

aboratory Network (EDPLN)

n of new pathogens in wildlife, domestic 

twinning initiatives and partnerships 

24

Expanding from HPAI

• CC

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

L L dLessons Learned– Disease and poverty

Disease and livelihood– Disease and livelihood

– Cross‐Sectoral collaboration

– CommunicationCommunication

– Political commitment

CapacityCapacity– Surveillance

– Emergency responseg y p

cific ECTAD ‐ RAP

25

Regional Laboratory NRegional Laboratory NAnimal Influenza Diag

•H5Clade 2.3.2Cleavage siteCYXXXXXXCYXXXXXXOther seqs: NA, PB2

•H5Clade 2.3.4

•Cleavage siteAAXXXXXXXOther seqs: NA, PB2

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

Networks forNetworks for nosis in SE AsiaNetwork of institutions, people and experts in the region on a sharing platformsharing platform– Technical assistance

– Diagnostic service 

– Information

Harmonized, accurate and timely diagnosisdiagnosis 

Better understanding of disease epidemiology at country and p gy yregional level

cific ECTAD ‐ RAP

26

• Surveillanc

Risk Reduction at Human• Surveillanc

– Sample a

• Accurate apathogens human hea

Diagnost– Diagnost

• Biosecurity– Bioexclu

– Biocontatransmis

Emergency Centre for Transboundary Animal Diseases for Asia and the Pac

AGA‐TCE

Food and Agriculture Organization of the United Nations

ce of diseases in livestock

n‐Animal Interfacece of diseases in livestockand data collection

nd timely identification of ythreatening animal and althtic and investigationtic and investigation

ysion: Prevent incursion

ainment : Prevent outward ssion

cific ECTAD ‐ RAP

27