Author Index

Abboud FM, Heistad DD, Mark AL, Schmid PG 155,202, 203

Abboud FM, Thames MD 195,202

Abboud FM, see Calvelo MG 136, 142, 155,204

Abdel-Sayed W, see Calvelo MG 136,142, 155,204

Abrahams VC, Hilton SM, Zbrozyna AW 152,203

Adams PR 74, 103,112 Adams PR, see Sakmann B

116 Adson AW, see Brown GE

156,204 Akerboom TPM, Bookelman

H, Zuurendonk PF, Meer R van der, Tager JM 7, 62

Akerboom TPM, see Meer R van der 52, 71

Akerman KEO, Nicholls DG 2, 3, 4, 16, 26, 29, 30, 33, 34, 36, 42, 55, 62, 63

Akerman KEO, see Scott ID 29, 30, 70

Akerman K, see Nicholls D 2, 25, 36, 69

Akoev GN 157,203 Alien DG, Blinks JR 32, 33,

44, 63 Altamirano-Orrego R, see

Loewenstein WR 157,210 Althaus-Salzmann M, Carafoli

E, Jakob A 53, 63 Amendt K, Czacharski J,

Dembowsky K, Seller H 198,203

Anderson CR, Stevens CF 75,105,112

Anderson HK, see Langley JN 171,209

Andersson PO 139,203 Andrews JP, see Hess GP 76,

77, 78, 80, 81, 86, 87,114 Aogaichi T, Evans J, Gabriel J,

Plaut GWF 6, 63 Aoshima H, Cash D J, Hess GP

78, 91, 95, 96, 97, 102, 104,112

Aoshima H, see Cash DJ 84, 90, 105,113

Aoshima H, see Hess GP 74, 77, 79, 86, 88, 90, 91, 100, 106,114

Aoshima H, see Ramseyer GO 88, 90, 116

Applebaum ML, see Coggeshall RE 173,205

Araneda G, see Karim F 140, 208

Assimacopoulos-Jeannet F, McCormack JG, Jeanrenaud B 51, 53, 57, 63

Austin, Costro, Hansford RG 14

Azzone GF, see Bragadin M 27, 63

Babcock DF, Chen J-LJ, Yip BP, Lardy HA 53, 63

Babcock DF, see Chen J-LJ 53,57,64

Baccelli G, see Mancia G 153, 210

Baccelli G, see Zanchetti A 153,213

Baddams HM, Chang LBF, Barritt GJ 57, 63

Baker PF 34, 63 Balaban RS, Blum JJ 52, 63 Baldissera F, Hultborn H,

Illert M 121,122, 124, 196,199,203

Ball AJ, see Sugden MC 51, 52, 57, 71

Ballantyne D, see Richter DW 138, 139,211

BaUard DR, see Calvelo MG 136, 142, 155,204

Bangham AD, Standish MM, Watkins JC 76, 77,112

Barasi S, Lynn B 158,203 Bard P 152,203 Bard P, Macht MB 152,

203 Bard P, Rioch DMcK 152,

203 Barker D, Saito M 157,203

Barman SW, Wurster RD 198,203

Baron R, Jiinig W, McLachlan EM 171,175, 177,203

Barritt GJ, Lamont SV 31, 63

Barritt GJ, Spiel PF 26, 63 Barritt G J, see Baddams HM

57, 63 Barritt GJ, see Foldes M 11,

66 Barritt G J, see Hughes BP

27, 67 Barritt GJ, see Whiting JA

57,72 Bartels E, see PodleskiTR 75,

116 Baschera C, see Crompton M

27, 65 Bassett D, see Fisher AB 12,

66 Biith E, Lindblad LE, Wallin

BG 190, 203 Baudry M, see Browning M

50, 64 Beck PW, Handwerker HO,

Zimmermann M 166, 203

Becker GL, Fiskum G, Lehninger AL 39,63

Beeton P, see Rossum GDV van 27, 71

Belfrage E, see Rosell S 126, 159,211

BeI1C 125,152, 155,203 Bell C, Jiinig W, Kiimmel H,

Xu H 154, 155,203 Bennett W, see Browning M

49, 50, 64 Bergman SA, see Wolthuis RA

190, 213 Berkoff HA, see Hunter DR

25, 26, 27, 67 BernardC 156,203 Bernhardt J, Neumann E

79, 87, 112 Bernstein J J, see Guth L 170,

206 Berthon B, see Charest R

35, 52, 53, 54, 56, 64

216 Author Index

Berthon B, see Poggioli J 28, 54, 70

Bessou P, Perl ER 166, 203

Bevington PR 100, 101, 108,109, 112

Bini G, Hagbarth KE, Hynninen P, Wallin BG 188,190, 191,192, 193, 203, 204

Bini G, Hagbarth KE, WaUin BG 189,192,204

Bishop GH, Heinbecker P 178,204

Blackman JG 194,204 Blackmore PF, Dehaye J-P,

Exton JH 27, 53, 54, 57, 63

Blackmore PF, Dehaye J-P, Strickland WG, Exton JH 27, 63

Blackmore PF, Hughes BP, Shuman EA, Exton JH 55, 63

Blackmore PF, see Charest R 35, 52, 53, 54, 56, 64

Blackmore PF, see Morgan NG 55, 56, 57, 69

Blair DA, Glover WE, Greenfield ADM, Roddie IC 193,204

Blair DA, see Golenhofen K 192,193,206

Blake DW, Blomberg PA, Korner PI 185,204

Blake DW, Korner PI 185, 204

Blass JP, see Gibson GE 50, 66

Btaustein MP 30, 31, 33, 42, 49, 63

Blaustein MP, Ector AC 31,63

Blaustein MP, see Schweitzer ES 42, 70

Blinks JR, Wier WG, Hess P, Prendergast FG 32,63

Blinks JR, see Allen DG 32, 33, 44, 63

Blinks JR, see Lhnas R 30, 33, 68

Blomberg PA, see Blake DW 185,204

Blum J J, see Balaban RS 52, 63

Blumberg H, Hilbers K, J~inigW 130, 133,138, 146, 151,204

Blumberg H, J/inig W 128, 135,136, 142, 156,158, 166,181,183, 185,196, 197,200,204

Blumberg H, J/inig W, Rieck- mann C, Szulczyk P 129, 133,135,136,140, 141,142, 143,204

Bonica JJ 156,204 Bonner WD Jr, see Moore AL

60,69 Bookelman H, see Akerboom

TPM 7, 62 BoppP 151,204 Borle AB 25, 26, 28, 32, 36,

63 Borle AB, Snowdowne KW

35, 63 Borle AB, see Studer RK

28, 71 Borst P 17, 19, 63 Boyd ND, see Neubig RR

107,116 Bragadin M, Pozzan T,

Azzone GF 27,63 Brand MD, Selincourt C De

39, 64 Brender D, Webb-Peploe MM

140,204 Bridges B J, see Denton RM

6, 65 Bridges B J, see Severson DL

58, 70 Brinley FJ Jr, Tiffert T,

ScarpaA 42, 64 Brinley FJ Jr, see DiPolo R

34, 65 Brocks DG, see Siess EA

51, 52, 71 Brooks CM 160,204 Brooks CM, see Koizumi K

121,160,209 Brostrom CO, Hunkeler FL,

Krebs EG 46, 64 Brown GE, Adson AW 156,

204 Browning M, Baudry M,

Bennett WF, Lynch G 50, 64

Browning M, Bennett WF, Kelly P, Lynch G 50, 64

Browning M, Dunwiddie T, Bennett W, Gispen W, Lynch G 49, 50, 64

Briicke ET von 156, 212

BryPa J, see Smith CM 8, 71

Buchholz M, see Klingenberg M 12,61,68

Buchwald J, see Eldred E 157,205

Banger R, Permanetter B, Sommer O, Yaffe S 45, 46, 64

Bulger JE, Fu J-JL, Hindy EF, Silberstein RL, Hess GP 88, 91, 92, 112

Bulger JE, see Hess GP 91, 114

Burn JH 152,204 Buysere M de, see Hiraoka T

46, 67 Bygrave FL 28, 39, 64 Bygrave FL, Daday AA, Doy

FA 60, 64 Bygrave FL, see Reinhart PH

52, 53, 54, 55, 56, 70 Bygrave FL, see Taylor WM

52, 53, 54, 71

Calhoun ML, see Strickland JH 125,151,212

Calof AL, Jones RB, Roberts WJ 156,204

Calvelo MG, Abboud FM, Ballard DR, Abdel-Sayed W 136, 142, 155,204

CannonWB 121, 156,205 Capano M, see Crompton M

15, 65 Carafoli E 28, 64 Carafoli E, Hansford RG,

Sacktor B, Lehninger AL 60, 64

Carafoli E, Lehninger AL 60, 64

Carafoli E, see Althaus- Salzmann M 53,63

Carafoli E, see Crompton M 15, 27, 36, 41, 50, 65

Carafoli E, see Malmstr6m K 10, 68

Cash D J, Aoshima H, Hess GP 84, 90, 105,113

Cash DJ, Hess GP 79, 82, 83, 85, 88, 90, 91, 99, 100, 102, 104,112, 113

Cash DJ, see Aoshima H 78, 91, 95, 96, 97, 102, 104, 112

Cash DJ, see Hess GP 74, 77, 79, 86, 88, 90, 91,100, 106, 107, 109, 110, 114

Cash DJ, see Walker JW 87, 111,117

Castro F, see Hansford RG 8, 16, 20, 21, 22, 23, 24, 28, 29, 30, 32, 36, 37, 40, 41, 42, 48, 49, 54, 59, 66

Chance B, Eisenhardt RH, Gibson QH, Lonberg-Holm KK 83, 113

Chance B, Williams GR 3, 59, 60, 64

Chance B, see Roughton FJW 83, 116

Author Index 217

Chang LBF, see Baddams HM 57, 63

ChangeuxJ-P 103, 105,111, 113

Changeux J-P, see Griinhagen HH 105,113

Changeux J-P, see Hazelbauer GH 77,106,113

Changeux J-P, see Heidmann T 105,113

Changeux J-P, see Kasai M 75, 76, 77, 78, 79,115

Changeux J-P, see Popot J-L 77,106, 116

Changeux J-P, see Sugiyama H 77, 106,116

Chaplain RA 12, 64 Chappell JB 17,64 ChappeU JB, see Hansford RG

12, 13, 61,66 Charest R, Blackmore PF,

Berthon B, Exton JH 35, 52, 53, 54, 56, 64

Chen J-L J, Babcock DF, Hardy HA 53, 57, 64

Chen J-I J, see Babcock DF 53, 63

ChernetskiKE 156,205 Chin JG, see Denton RM

5,6,7,65 Chrisman TD, Jordan JE,

Exton JH 53, 64 Chun RWS, see Wang GH

151,213 Claret-Berthon B, Claret M,

Mazet JL 27, 28, 64 Claret M, see Claret-Berthon B

27, 28, 64 Claret M, see Poggioli J 28,

54, 70 Claus TH, Pilkis SJ 57, 64 Cockett FB, see Tracy GD

156,212 Coggeshall RE, Galbraith SL

173,205 Coggeshall RE, Hancock MB,

Applebaum ML 173,205 Cohen JB, see Neubig RR

106,107,116 Cohen JB, see Sugiyama H

77, 106, 116 Cohen L, see Hansford RG

15, 33, 50, 60, 66 Coil KE, Joseph SK, Corkey

BE, Williamson JR 21, 23, 24, 28, 29, 30, 31, 36, 37, 41,53, 54, 55, 64

Coil K, see Murphy E 21, 23, 27, 28, 29, 34, 35, 53, 54, 55,56,69

Coombs SE, see Hess GP 76, 77, 78, 80, 81,114

Cooper RH, Randle PJ, Denton RM 6, 10,65

Cooper RH, see Denton RM 6, 65

Cooper RH, see Williamson JR 29, 54, 72

Coore HG, see Denton RM 58, 65

Coote JH 197,205 Coote JH, MacLeod VH 198,

205 Corkey BE, Hale DE 55, 65 Corkey BE, see Coil KE 21,

23, 24, 28, 29, 30, 31, 36, 37, 41,53, 54, 55, 64

Crane D, see Sies H 51, 71 Crompton M, Capano M,

Carafoli E 15, 65 Crompton M, Held I 15, 65 Crompton M, Heid I, Baschera

C, Carafoli E 27, 65 Crompton M, Kunzi M,

Carafoli E 36, 65 Crompton M, Moser R, Liidi

H, Carafoli E 41,50,65 Crompton M, Sigel E,

Salzmann M, Carafoli E 15,65

Crompton M, see Goldstone TP 41,55,66

Crompton M, see Kessar P 44, 55, 67

Crompton M, see Nicholls DG 39,69

Culp W, see Marchettini P 192

Czacharski J, see Amendt K 198, 203

Czachurski J, see Dembowsky K 198, 205

Czech MP, see Seals JR 58, 70

Daday AA, see Bygrave FL 60, 64

Daly MdeB, Scott MJ 136, 2O5

Dampney RAL 199,205 Davidheiser S, see Tedeschi

RE 136,212 Davis EJ, Lumeng L 7, 65 Davis J, see Henry PD 25,

66 Dehaye J-P, see Blackmore PF

27, 53, 54, 57, 63 Delgeane A, McNamee MB

106, 113 Delius W, Hagbarth KE,

Hongell A, Wallin BG 189, 191,205

Delius W, see Wallin BG 190, 213

Dembowsky K, Lackner K, Czachurski J, Seller H 198,205

Dembowsky K, see Amendt K 198,203

Denton RM, Coore HG, Martin BR, Randle PJ 58, 65

Denton RM, Hansford RG 15

Denton RM, Hughes WA 58, 65

Denton RM, McCormack JG 3, 7, 15, 17, 18, 35, 41, 57, 62, 65

Denton RM, McCormack JG, EdgeUNJ 15, 17,41, 65

Denton RM, McCormack JG, OviasuOA 51, 57,65

Denton RM, Randle PJ, Martin BR 4, 65

Denton RM, Randle PJ, Bridges B J, Cooper RH, Kerbey AL, Pask HT, Severson DL, Stansbie D, Whitehouse S 6, 65

Denton RM, Richards DA, ChinJG 5, 6, 7, 65

Denton RM, see Cooper RH 6, 10, 65

Denton RM, see Hems DA 51,53,66

Denton RM, see Hughes WA 58 ,67

Denton RM, see Marshall SE 58, 68

Denton RM, see McCormack JG 5, 7, 8, 9, 17, 18, 24, 41, 45, 46, 48, 49, 50, 58, 59, 60, 68

Denton RM, see Randle PJ 5,8, 70

Denton RM, see Severson DL 15, 58, 70

Devor M 156,205 DiPolo R, Requena J, Brinley

FR Jr, Mullins LJ, Scarpa A, Tiffert T 34, 65

Donner DB, see Fu J-JL 88, 113

Doy FA, see Bygrave FL 60, 64

Dresdner K, see Lee CO 32, 68

Duddridge RJ, see Goldstone TP 41, 55, 66

Dunwiddie T, see Browning M 49, 50, 64

Dusser de Barenne JG 156, 2O5

Eckberg DL, see Wallin BG 190, 213

218 Author Index

Ector AC, see Blaustein MP 31, 63

Ectors L 152,205 Edgell N J, see Denton RM

15, 17, 41, 65 Eisenhardt RH, see Chance B

83,113 Elardo SM, see Roberts WJ

158,211 Eldred E, Schnitzlein HN,

Buchwald J 157,205 Eliasson S, Folkow B,

Lindgren P, Uvn~s B 152, 205

Ellison GD, ZanchettiA 153, 205

Ellison GD, see Zanchetti A 153,213

Endo M, see Somlyo AP 24, 27, 31, 71

England P J, see McCormack JG 46, 47, 49, 68

England P J, see Randle PJ 8,70

Epstein N, Hess GP, Kim PS, Noble RL 78,113

Epstein N, Racker E 112, 113

Erecmska M, see Nishiki K 9,69

Evans J, see Aogaichi T 6, 63

Exton JH 54, 65 Exton JH, see Blackmore PF

27, 53, 54, 55, 57, 63 Exton JH, see Charest R

35, 52, 53, 54, 56, 64 Exton JH, see Chrisman TD

53, 64 Exton JH, see Morgan NG

55, 56, 57, 69 Exton JH, see Taylor WM

54, 71 Ezawa I, Ogata E 10, 11, 65

Farnsworth DI, see Kuntz A 175,209

Fersht AR, Jakes R 83, 84, 113

Fiol C, see Wonnacott S 31, 72

Fisher AB, Scarpa A, LaNoue KF, Bassett D, Williamson JR 12, 66

Fiskum G, Lehninger AL 2, 4, 16, 25, 36, 66

Fiskum G, see Becker GL 39, 63

Fitzgerald M 166,205 Fleckenstein A 46,66 Fleming J, see Giorgio NA Jr

6,66

Foden S, Randle PJ 27, 28, 66

Foldes M, Barritt GJ 11, 66 Folkow B 125,205 Folkow B, Neil E 121,125,

140,205 Folkow B, see Eliasson S

152,205 Ford WCL, see Illingworth JA

8 ,9 ,45 ,67 Foreman RD, Wurster RD

198,205 Fozzard HA, see Lee CO 15,

68 Francavilla A, see Papa S

17, 69 Frankel HL, Mathias CJ 161,

162,205 Freeman B, Rowe M 157,

158,205 Friedmann N, Rasmussen H

57, 66 Froehlich JP, Taylor EW 83,

113 Froehlich JP, see Sumida M

83,117 Fu J-JL, Donner DB, Hess GP

113 Fu J-JL, Donner DB, Moore

DE, Hess GP 88, 113 Fu J-JL, see Bulger JE 88, 91,

92,112 Fu J-JL, see Hess GP 91,114 Fulton JF, see Sahs AL 160,

211

Gabriel J, see Aogaichi T 6, 63

Gabriel M, see Illert M 198, 207

Galbraith SL, see Coggeshall RE 173,205

Gibson GE, Jope R, Blass JP 50,66

Gibson GE, Peterson C 50,66 Gibson QH, see Chance B 83,

113 Gilman A, see Gilman AG

185,206 Gilman AG, Goodman LS,

Gilman A 185,206 Giorgio NA Jr, Yip AT,

Fleming J, Plant GWE 6,66

Gispen W, see Browning M 49, 50, 64

Glover WE, see Blair DA 193, 2O4

Goldin SM, Rhodin V, Hess EJ 86,113

Goldman Y, see Morad M 33, 69

Goldstone TP, Crompton M 55, 66

Goldstone TP, Duddridge R J, Crompton M 41, 55, 66

Golenhofen K 192, 193,206 Golenhofen K, Blair DA,

Seidel W 192, 193,206 Golenhofen K, Hildebrandt G

192, 193,206 Goodman LS, see Gilman AG

185,206 Gottesman DP, see Walajtys

El 15, 72 Graf P, see Sies H 51, 71 Graham BH, Lioy F 155,206 Granit R 195, 196, 199,206 Graziotti P, see Scarpa A 32,

33, 44, 70 Greenfield ADM, see Blair DA

193,204 Gregor M, J~inig W 129, 133,

136, 137, 140, 142,143, 199,206

Grewe W, J~inig W, Kiimmel H, Varma S 129,130, 133, 147, 151,206

Gregor M, J~inig W, Riedel W 130, 133, 146, 155,206

Gregor M, J~nig W, Wiprich L 129, 133, 135,136, 140, 141,147,206

Grillner S 122,206 Gripenberg J, see Jansson SE

31,67 Groat WC de, see Kuo DC

171,177,209 Groen AK, see Meer R van der

52, 71 Grosse M, J~nig W 129, 133,

140, 143, 144,145,151, 152,179, 181,183,206

Griinhagen HH, Changeux J-P 105,113

GrOnhagen HH, lwatsubo M, Changeux J-P 105,113

Gupta BL, Hall TA 25, 66 Guth L, Bernstein JJ 170,

206 Guttmann L 159, 160, 161,

162, 206 Guynn RW, see Veloso D 15,

71

Haan EJ de, Tager JM, Slater EC 17, 65

Haan EJ de, see Papa S 17, 69

H@k6nen M, see Jansson SE 31,67

Hagbarth KE, Hallin RG, Hongell A, Torebj~irk HE, Wallin BG 190, 206

Author Index 219

Hagbarth KE, see Bini G 188,190, 191,192, 193, 203, 204

Hagbarth KE, see Delius W 189,191,205

Hagbarth KE, see Vallbo AB 187,193,212

Hainsworth R, Linden RJ 140,206

Hainsworth R, see Karim F 140, 208

Hale DE, see Corkey BE 55, 65

HallM 159,206 Hall TA, see Gupta BL 25,

66 Hallin RG, Torebj6rk HE

188,191,206 Hallin RG, Wiesenfeld-Hallin Z

157,158,206 HaUin RG, see Hagbarth KE

190,206 Hammes GG 83, 90, 113 Hammes GG, Wu CW 113 Hancock MB, see Coggeshall

RE 173,205 Handwerker HO, see Beck PW

166,203 Hansford RG 4,6, 8, 14, 15,

18, 32, 45, 59, 60, 66 Hansford RG, Castro F 8, 16,

20, 21, 22, 23, 24, 28, 29, 30, 32, 36, 37, 40, 41,42, 48, 49, 54, 59, 66

Hansford RG, Chappell JB 12, 13, 61,66

Hansford RG, Cohen L 15, 33, 50, 60, 66

Hansford RG, see Carafoli E 60, 64

Hansford RG, see Denton RM 15

Hansford RG, see Johnson RN 8, 55,67

Hardy HA, see Chen J-LJ 53, 57, 64

Harris RA, see Paxton R 10, 69

Hartig PR, see Miller DL 77,106,115

Hassinen IE, see Hiltunen JK 9, 45,66

Hassinen IE, see Kauppinen RA 59, 62, 67

Haworth RA, see Hunter DR 25, 26, 27, 67

Hazelbauer GH, Changeux J-P 77,106,113

Head H, Riddoch G 160, 206

Head H, see Riddoch G 160, 211

Heaton GM, Nieholls DG 23, 66

Heid I, see Crompton M 15, 27, 65

Heidmann T, Changeux J-P 105,113

Heinbecker P, see Bishop GH 178,204

Heistad DD, see Abboud FM 155,202, 203

Hellmann K 152,206 Hems DA, McCormack JG,

Denton RM 51,53,66 Henry PD, Shuchleib R, Davis

J, Weiss ES, Sobel BE 25, 66

Hensel H 146,207 Hess E J, see Goldin SM 86,

113 Hess GP 79, 85, 86,114 Hess GP, Andrews JP 77, 78,

80 ,86 ,87 ,114 Hess GP, Andrews JP, Struve

GE 77,114 Hess GP, Andrews JP, Struve

GE, Coombs SE 76, 77, 78 ,80 ,81 ,114

Hess GP, Aoshima H, Cash D J, Lenchitz B 86, 88, 90, 100, 106,114

Hess GP, Bulger JE, Fu J-JL, Hindy EF, Silberstein RJ 91,114

Hess GP, Cash DJ, Aoshima H 74, 77, 79, 91,114

Hess GP, Kolb H-A, L~iuger P, Schoffeniels E, Sehwarze W 106, 114

Hess GP, Lipkowitz S, Struve GE 78, 81, 92, 114

Hess GP, Pasquale EB, Karpen JW, Sachs AB, Takeyasu K, Cash DJ 87,106, 107, 109, 110,114

Hess GP, Pasquale EB, Walker JW, McNamee MG 87, 106, 107,109, 110,114

Hess GP, see Aoshima H 78, 91, 95, 96, 97, 102, 104, 112

Hess GP, see Bulger JE 88, 91 ,92 ,112

Hess GP, see Cash DJ 79, 82, 83, 84, 85, 88, 90, 91, 99, 100, 102,104, 105,112, 113

Hess GP, see Epstein N 78, 113

Hess GP, see Fu J-JL 88, 113

Hess GP, see Kim PS 77, 80, 81, 83, 87, 99,115

Hess GP, see Leprinee P 91, 115

Hess GP, see Ramseyer GO 88, 90, 116

Hess GP, see Sachs AB 80, 116

Hess GP, see Walker JW 87, 111,117

Hess P, see Blinks JR 32, 63 Heuser JE, see Llin~s RR 33,

68 Hilbers K, J~inig W 145 Hilbers K, see Blumberg H

130, 133, 138, 146, 151, 204

Hildebrandt G, see Golenhofen K 192, 193, 206

Hilton SM, Spyer KM 122, 207

Hilton SM, see Abrahams VC 152,203

Hilton SM, see Koepchen HP 122,209

Hiltunen JK, Hassinen IE 9, 45, 66

Hiltunen JK, see Kauppinen RA 59, 62, 67

Hindy EF, see Buiger JE 88, 91, 92, 112

Hindy EF, see Hess GP 91, 114

Hinkle PC, see Thayer WS 83, 117

Hiraoka T, Buysere M de, Olson MS 46,67

Hirst GDS, see McLachlan EM 171,210

Hisamitsu T, see Kuo DC 171,177,209

Hoek JB, see Williamson JR 54, 72

H6kfelt T, Johansson O, Ljungdahl A, Lundberg JM, Schutzberg M 154,207

Hoffmeister B, Husseis W, J~inig W 196, 197,207

Holian A, see Wilson DF 52, 72

Homma S 195,207 Hongell A, see Hagbarth KE

190, 206 HongeU A, see Delius W 189,

191,205 Horeyseck G, Jiinig W 123,

129,133,134, 137, 143, 144,154, 159, 160, 161, 163, 185,207

Horeyseck G, J~inig W, Kirchner F, Th~imer V 123, 129,133, 153, 154, 181,183,207

220 Author Index

Horwitz TS, Kaufman AI 150,207

Huganir RL, ScheU MA, Racker E 112,114

Hughes BP, Barritt GJ 27 ,67

Hughes WA, Denton RM 58 ,67

Hughes BP, see Blaekmore PF 55,63

Hughes WA, see Denton RM 58, 65

Hultborn H, see Baldissera F 121,122, 124, 196, 199, 203

Hunkeler FL, see Brostrom CO 46, 64

Hunsperger RW 151,207 Hunt CC 157,207 Hunt CC, Jami L, Laporte Y

157,207 Hunter DR, Komai H,

Haworth RA, Jackson MD, Berkoff HA 25, 26, 27, 67

Hussels W, see Hoffmeister B 196,197,207

Hynninen P, see Bini G 188, 190, 191,192, 193,203, 204

Ibata Y, see Santini M 157, 211

llic V, see Sugden MC 51, 52, 57, 71

Illert M, Gabriel M 198,207 Ulert M, Seller H 198,207 Illert M, see Baldissera F 121,

122, 124,196, 199,203 lllingworth JA, Ford WCL,

Kobayashi K, Williamson JR 8,9,45,67

Illingworth JA, Mullings R 45, 67

Ineichen A, see Stucki JW 15, 71

Inesi G, see Kurzmack M 83, 115

Inesi G, see Somlyo AP 24, 27, 31, 71

Inesi G, see Verjovski-Almeida S 83 ,117

Iriki M, Kozawa E 143,199, 207

Iriki M, Pleschka K, Walther OE, Simon E 142,207

Iriki M, see Simon E 146, 212

lrisawa H, see Ninomiya I 140,210, 211

Ivanov AY, see Skok VI 194, 212

Iwatsubo M, see Griinhagen HH 105,113

Jackson MD, see Hunter DR 25, 26, 27, 67

Jacob R, see Wendt-Gallitelli MF 24, 72

J~nig W 123,133, 137,143, 144, 149, 161,162, 164, 168, 185,193,194,197, 207, 208

J~ig W, Krauspe R, Wiedersatz G 125,127, 166, 187,196, 197,208

J~igW, Kiimmel H 128, 129, 130, 133,134,142, 143,144,145,148,149, 150, 151,154,155,159, 160, 163,164,166, 169, 181,183,196, 197,198, 208

J~inig W, Kiimmel H, Wiprich L 133, 138,139, 148,151, 208

J~nig W, McLachlan EM 172, 174,177,208

J~nigW, R~ith B 128, 129, 133, 148, 150, 186,208

Jtinig W, Sato A, Schmidt RF 123,208

JtinigW, Schmidt RF 123, 171,172, 173,208

J~-lig W, Schmidt RF, Zimmermann M 165,208

Jtinig W, Spilok N 129,134, 159, 160, 163,164,165, 166,208

Jtinig W, Sundl6f G, WaUin BG 125,127,187,196,197, 208

J~inig W, Szulczyk P 127, 128, 133,171,172,173, 178,179,180, 181,183, 198,208

Jiinig W, see Baron R 171, 175,177,203

J~Lrtig W, see Bell C 154, 155, 203

J~inig W, see Blumberg H 128, 129,130, 133, 135, 136, 138, 140, 141,142, 143,146, 151,156,158, 166,181,183, 185,196, 197, 200, 204

J~nig W, see Gregor M 129, 130, 133,135,136,137, 140, 141,142, 143,146, 147, 155,199,206

J~inig W, see Grewe W 129, 130, 133,147,151,206

J~nig W, see Grosse M 129, 133, 140, 143, 144,145,

151,152, 179, 181,183, 206

J~inig W, see Horeyseck G 123, 129, 133,134, 137, 143, 144,145,153, 154, 159, 160, 161,163, 181, 183, 185,207

Jiinig W, see Hoffmeister B 196, 197,207

Jtinig W, see McLaehlan EM 127,130, 174, 175,176, 181,182, 184,210

Jakes R, see Fersht AR 83, 84,113

Jakob A, see Althaus- Salzmann M 53,63

Jami L, see Hunt CC 157, 207

Jankowska E, Lundberg A 121,208

Jansson SE, Gripenberg J, H~k6nen M, Korpijoki P 31 ,67

Jarett L, Seals JR 58, 67 Jarett L, see Kiechle FL 58,

67 Jeanrenaud B, see

Assimacopoulos-Jeannet F 51,53,57,63

Johansson B, see Mellander S 146,210

Johansson O, see H6kfelt T 154,207

Johnson JD, see V[ghy PL 49, 71

Johnson RN, Hansford RG 8, 55, 67

Jones RB, see Calof AL 156, 204

Jo6 F, see Parducz A 30, 49, 69

Jope R, see Gibson GE 50, 66

Jordan JE, see Chrisman TD 53, 64

Joseph SK, Williamson JR 27, 28, 29, 39, 40, 41, 44, 54, 56, 67

Joseph SK, see Coil KE 21, 23, 24, 28, 29, 30, 31, 36, 37, 41, 53, 54, 55, 64

Jih-ss R, Prinz H, Maelicke A 105,114

Jungas RL 58, 67

Kaback HR 75, 76, 77, 112, 114

KandelER 74,114, 121, 208

Karim F, Araneda G, Hainsworth R 140,208

Karlin A 74, 88,106, 114

Autho r lndex 221

Karpen JW, see Hess GP 87, 106,107,109,110,114

Kasai M, Changeux J-P 75, 76, 77, 78, 79, 115

KatzAM 46,67 KatzB 103,115 Katz B, Miledi R 30, 33, 67,

75, 77,105,115 Katz B, ThesleffS 77, 91,

92,103,115 Kaufman A, Koizumi K 171,

208 Kaufman AI, see Horwitz TS

150,207 Kauppinen RA, Hiltunen JK,

Hassinen IE 59, 62, 67 Keilin D 59,67 Kelly P, see Browning M 50,

64 Kendrick E, Oberg B,

WennergrenG 136,140, 141,209

Kenins P, see Perl ER 166, 211

Kerbey AL, see Denton RM 6, 65

Kessar P, Crompton M 44, 55,67

Keynes RD, Martins-Ferreira H 75,115

Khono H, see Sugano T 52, 71

Kiechle FL, Jarett L, Kotagal N, Popp DA 58,67

Kim PS 88,115 Kim PS, Hess GP 77, 80, 81,

83, 87, 99,11.5 Kim PS, see Epstein N 78,

113 Kirchheim HR 129,195,

209 Kirchner F, see Horeyseck G

123, 129, 133,153,154, 181,183,207

Klingenberg M, Buchholz M 12, 61,68

Kobayashi K, see Illingworth JA 8,9,45,67

K6nig U, see Wallin BG 187, 213

Koepchen HP, Hilton SM, TrzebskiA 122,209

KoizumiK, Brooks CM 121, 160,209

Koizumi K, see Kaufman A 171,208

Kolb H-A, see Hess GP 106, 114

Komai H, see Hunter DR 25, 26, 27,67

Korner PI 121,136, 137, 142, 185,209

Korner PI, Uther JB 136, 137,142,209

Korner PI, see Blake DW 185,204

Korpijoki P, see Jansson SE 31,67

Kosterlitz HW, Thompson JW, WaUis DI 179,209

Kotagal N, see Kiechle FL 58,67

Kozawa E, see Iriki M 143, 199,207

Krauspe R, see J~inig W 125, 127, 166,187,196,197, 2O8

Krebs EG, see Brostrom CO 46, 64

Kiimmel H 134,159, 160, 161,162, 163,166,209

Kiimmel H, Xu H 161,162, 164, 166,209

Kiimmel H, see Bell C 154, 155,203

Kiimmel H, see Grewe W 129,130, 133,147,151, 206

Kiimmel H, see J~nig W 128, 129, 130, 133, 134, 138, 139, 142, 143, 144, 145, 148, 149, 150, 151, 154, 155, 159, 160, 163, 164, 166, 169, 181, 183, 196, 197, 198,208

Kuhn RA 159,160, 209 Kumarzawa T, see Perl ER

166,211 Kuntz A 175,209 Kuntz A, Farnsworth DI

175,209 Kuntz A, Saecomanno G

175,209 Kunzi M, see Crompton M

36, 65 Kuo DC, Hisamitsu T, Groat

WCde 171,177,209 Kurzmack M, Verjovski-

Almeida S, Inesi G 83, 115

Lackner K, see Dembowsky K 198,205

L~iuger P, see Hess GP 106, 114

Lamont SV, see Barritt GJ 31, 63

LangerGA, Nudd LM 26, 68 Langley JN 125,127,151,

170, 175,176,209 Langley JN, Anderson HK

171,209 Langley JN, Sherrington CS

125,151,176,209

La Noue KF, see Fisher AB 12, 66

Laporte Y, see Hunt CC 157, 207

Lardy HA, see Babcock DF 53, 63

Lardy HA, see Reed PW 23, 70

Lardy HA, see Wernette ME 12, 13, 72

Lawinska E, see Martonosi A 83,115

Lawlis VB, Roche TE 8, 9, 68

Lee CO, Fozzard HA 15, 68

Lee CO, Uhm DY, Dresdner K 32,68

Lee CY 75, 88, 92,115 Lehninger AL 75, 76, 77,

115 Lehninger AL, see Becker GL

39, 63 Lehninger AL, see Carafoli E

60, 64 Lehninger AL, see Fiskum G

2, 4, 16, 25, 36, 66 Leitner JM, Perl ER 157,209 Lenehitz B, see Hess GP 86,

88, 90, 100, 106, 114 Lenchitz B, see Sachs AB 80,

116 Leprince P 87,115 Leprince P, Noble RL, Hess

GP 91,115 Lester HA, see Sheridan RE

116 Lewis T, Marvin HM 125,

151,210 Leyhausen P 151,210 Lichtman JW, see Purves D

170, 171,211 Lindblad LE, see B~th E 190,

203 Linden R J, see Hainsworth R

140, 206 Lindgren P, see Eliasson S

152,205 Lindstrom J, Patrick J 115 Lioy F, see Graham BH 155,

206 Lipkowitz S, see Hess GP

78, 81, 92, 114 LisanderB 125,152,210 Little R, ~JbergB 136,141,

142,143,210 Litwin MS 156,210 LivingstonWK 156,210 Ljungdahl A, see H6kfelt T

154,207 Llin~s R, Blinks JR, Nicholsen

C 30, 33, 68

222 Author Index

Llin~s RR, Heuser JE 33, 68 L6ffler G, see Patzelt C 57,

69 L6ffler G, see Weiss L 58,

72 LoewensteinWR 156,210 Loewenstein WR, Altamirano-

Orrego R 157,210 Loewy AD 198,210 Loewy AD, Neil JJ 198,210 Lonberg-Holm KK, see Chance

B 83,113 Lov6n C 144, 191,210 Liidi H, see Crompton M 41,

50, 65 Lumeng L, see Davis EJ 7,

65 Lundberg A 154, 199,210 Lundberg A, see Jankowska E

121,208 Lundberg JM, see H6kfelt T

154,207 Lymn RW, Taylor EW 83,

115 Lynch G, see Browning M

49, 50, 64 Lynn B 166,210 Lynn B, see Barasi S 158,

203 Lynn B, see PerlER 166,

211

Macht MB, see Bard P 152, 203

MacLeod VH, see Coote JH 198,205

Maelicke A, see Jiirss R 105, 114

Malmstr6m K~CarafoliE 10, 68

Mancia G 142,210 Mancia G, BacceUi G,

ZanchettiA 153,210 Mancia G, see Zanchetti A

153,213 Mandel F, see Sumida M 83,

117 Mandel L J, see Murphy E 29,

34, 35, 69 Mannard A, Polosa C 171,

210 Manning JW, see Takeuchi T

154,212 Marban E, Rink TJ, Tsien RW,

Tsien RY 32, 33, 44, 68 Marchbanks RM, see

Wonnacott S 31, 72 Marchettini P, Torebj6rk E,

Culp W, Ochoa J 192 Mark AL, see Abboud FM

155,202, 203

Marshall SE, McCormack JG, Denton RM 58,68

Martin BR, see Denton RM 4, 58, 65

Martins-Ferreira H, see Keynes RD 75,115

Martonosi A, Lawinska E, Oliver M 83,115

Marvin HM, see Lewis T 125,151,210

Mathias C J, see Frankel HL 161,162,205

Matlib MA, see V~ghy PL 49, 71

Mazet JL, see Claret-Berthon B 27, 28, 64

McConneU HM, see McNamee MG 77,115

McCormack JG, Denton RM 5, 7, 8, 9, 17, 18, 24, 41, 45, 46, 48, 49, 50, 58, 59, 60, 68

McCormack JG, England PJ 46, 47, 49, 68

McCormack JG, see Assimacopoulos-Jeannet F 51 ,53 ,57,63

McCormaek JG, see Denton RM 3, 7, 15, 17, 18, 35, 41, 51, 57, 62, 65

McCormack JG, see Hems DA 51,53,66

McCormack JG, see Marshall SE 58, 68

McLachlan EM, Hirst GDS 171,210

McLachlan EM, J~inig W 127, 130, 174,175,176, 181, 182, 184,210

McLachlan EM, see Baron R 171,175,177,203

McLachlan EM, see J~inig W 172, 174,177,208

McNamee MB, see Delgeane A 106,113

McNamee MG, McConnell HM 77,115

McNamee MG, see Hess GP 87, 106,107,109, 110, 114

McNamee MG, see Walker JW 87,111,117

Meer R van der, Akerboom TPM, Groen AK, Tager JM 52, 71

Meer R van der, see Akerboom TPM 7, 62

Meijer A J, van Woerkom GM, Steinman R, Williamson JR 10,69

MeUander S, Johansson B 146,210

Miledi R, see Katz B 30, 33, 67, 75, 77, 105,115

Miller DL, Moore H-PH, Hartig PR, Raftery MA 77, 106, 115

Mitchell P 59, 69 Moore AL, Bonner WD Jr 60,

69 Moore CL 46, 69 Moore DE, see Fu J-JL 88,

113 Moore H-PH, Raftery MA

106, 107,115 Moore H-PH, see Miller DL

77,106, 115 Morad M, Goldman Y 33, 69 Morgan DG, Routtenberg A

49,50,69 Morgan NG, Blackmore PF,

Exton JH 55, 56, 57, 69 Moriarity CM 30, 69 Morrison GH, see Ramseyer

GO 88, 90,116 Moser R, see Crompton M

41, 50, 65 Muller K J, Nicholls JG, Stent

GS 121,210 Muller-Ruchholtz ER, see

Reinauer H 45, 70 Mullings R, see Illingworth JA

45, 67 Mullins L J, see DiPolo R 34,

65 Murphy E, Coil K, Rich TL,

Williamson JR 21, 23, 27, 28, 29, 34, 35, 53, 54, 55, 56,69

Murphy E, Mandel LJ 29, 34, 35, 69

Murphy E, see Williamson JR 21,34, 72

Murray JG, Thompson JW 170, 210

Nachmansohn D 75,116 Nachmansohn D, Neumann E

75,116 Nachmansohn D, see

Schoffenieis E 75,116 Neely JR, Rovetto MJ, Oram

JF 8, 69 Nehr E, Sakmann B 75,105,

106, 116 Neher E, Stevens CF 77,

116 Neher E, see Sakmann B 116 Neil E, see Folkow B 121,

125,140,205 Neil JJ, see Loewy AD 198,

210 Neubig RR, Boyd ND, Cohen

JB 107,116

A u t h o r l n d e x 223

Neubig RR, Cohen JB 106, 107,116

Neumann E, see Bernhardt J 79, 87,112

Neumann E, see Nachmansohn D 75,116

Nicholls D, Akerman K 2, 25, 36, 69

Nicholls D, see Zoccarato F 41,44, 72

Nicholls DG 15, 24, 39, 48, 50, 53, 54, 69

Nicholls DG, Crompton M 39,69

Nicholls DG, Scott ID 42, 69

Nicholls DG, see Akerman KEO 2 , 3 , 4 , 1 6 , 2 6 , 2 9 , 30, 33, 34, 36, 42, 55, 62, 63

Nicholls DG, see Heaton GM 23, 66

Nicholls DG, see Scott ID 29, 30, 70

Nicholls JG, see Muller KJ 121,210

Nicholsen C, see Llin~s R 30, 33, 68

Nicogossian AE, see Wolthuis RA 190,213

Nilsson BY 157,210 Ninomiya I, Irisawa H 140,

210 Ninomiya I, hisawa A,

Nisimaru N 140,211 Nishiki K, Ereci~ska M, Wilson

DF 9, 69 Nisimaru N, see Ninomiya I

140,211 Nj~ A, Purves D 170,211 Noble RL, see Epstein N 78,

113 Noble RL, see Leprince P 91,

115 Noble RL, see Sachs AB 80,

116 Nudd LM, see Langer GA 26,

68 Nystrtim TG 156,211

Oberg B, see Kendrick E 136, 140, 141,209

Oberg B, see Little R 136, 141,142, 143,210

Ochoa J, see Marchettini P 192

Ochs RS, see Wernette ME 12, 13, 72

Ogata E, see Ezawa I 10, 11, 65

Oliver M, see Martonosi A 83,115

Olson MS, see Hiraoka T 46, 67

Olson MS, see Patel TB 10, 69

Ontko JA, see Otto DA 11, 69

Oram JF, see Neely JR 8, 69 Oshino N, see Sugano T 52,

71 Oskarsson M, see Veloso D

15, 71 Otto DA, Ontko JA 11, 69 Oviasu OA, see Denton RM

51, 57, 65 Owen CS, see Wilson DF 52,

72 Ozawa E 34, 46, 69

Papa S, Tager JM, Francavilla A, Haan EJ de, Quagliariello E 17, 69

Pappas GD, see Santini M 157,211

ParduczA, Jo6 F 30, 49, 69 Pask HT, see Denton RM

6, 65 Pask HT, see Randle PJ 5, 70 Pask HT, see Severson DL

15, 70 Paquale E, see Walker JW

87 ,111 ,117 Pasquale EB, see Hess GP 87,

106, 107,109, 110, 114 Passow H 76, 116 Patel TB, Olson MS 10, 69 Patlack J, see Sakmann B

116 Patrick J, see Lindstrom J

115 Patzelt C, L6ffler G, Wieland

OH 57, 69 Paxton R, Harris RA 10, 69 Pearse F J, Walajtys-Rode E,

WiUiamson JR 45, 70 Pelletier CL 136,142,211 Peiletier CL, Shepherd JT

142, 211 Perl ER, Kumarzawa T, Lynn

B, Kenins P 166,211 Perl ER, see Bessou P 166,

203 Perl ER, see Leitner JM 157,

209 Permanetter B, see Biinger R

45, 46, 64 Peter W, RiedelW 155,211 Peterson C, see Gibson GE

50, 66 Pette H 156,211 Pettit FH, Roche TE, Reed LJ

6 ,70 PickJ 175,211

Pierce JP, Roberts WJ 157, 211

Pilkis SJ, see Claus TH 57, 64 Plaut GWF, see Aogaichi T

6, 63 Plaut GWE, see Giorgio NA Jr

6, 66 Pleschka K 155,211 Pleschka K, see Iriki M 142,

207 Podleski TR, Bartels E 75,

116 Poggioli J, Berthon B, Claret

M 28,54, 70 PolosaC 171,172,211 Polosa C, Wyszogrodski I

171,211 Polosa C, see Mannard A

171,210 Popot J-L, Sugiyama H,

Changeux J-P 77, 106, 116

Popot JL, see Sugiyama H 77, 106, 116

Popp DA, see Kiechle FL 58, 67

Potter JD, see Robertson SP 32, 33, 70

Pozzan T, see Bragadin M 27, 63

Pozzan T, see Tsien RY 35, 44, 71

Prendergast FG, see Blinks JR 32, 63

Prinz H, see Jiirss R 105,114 Prpi~ V, see Taylor WM 54,

71 Purves D, Lichtman JW 170,

171,211 Purves D, Wigston DJ 196,

211 Purves D, see Nj~l A 170, 211

QuagliarieUo E, see Papa S 17, 69

RackerE 75,76, 77, 112, 116

Racker E, see Epstein N 112, 113

Racker E, see Huganir RL 112, 114

R~ith B, see Jiinig W 128, 129, 133, 148, 150, 186, 208

Raftery MA, see Miller DL 77, 106,115

Raftery MA, see Moore H-PH 106, 107, 115

Ramseyer GO, Morrison GH, Aoshima H, Hess GP 88, 90, 116

224 A u t h o r Index

Randle P J, Denton RM, Pask HT, Severson D 5, 70

Randle P J, England PJ, Denton RM 8, 70

Randle PJ, see Cooper RH 6, 10, 65

Randle P J, see Denton RM 4, 58,.65

Randle PJ, see Foden S 27, 28, 66

Randle PJ, see Severson DL 15, 58, 70

Rang HP 116 Rasmussen H, Waisman DM

25,44, 70 Rasmussen H, see Friedmann

N 57,66 Reed LJ 4, 45, 70 Reed L J, see Pettit FH 5, 70 Reed PW, Lardy HA 23, 70 Reinauer H, Muller-Ruchholtz

ER 45, 70 Reinhart PH, Taylor WM,

Bygrave FL 52, 53, 54, 55, 56, 70

Reinhart PH, see Taylor WM 52, 53, 71

Requena J, see DiPolo R 34, 65

Rhodin V, see Goldin SM 86,113

Rich TL, see Murphy E 21, 23, 27, 28, 29, 34, 35, 53, 54, 55, 56, 69

Richards DA, see Denton RM 5 , 6 , 7 , 6 5

Richards RL 156,211 Richter DW 138, 139,211 Richter DW, BaUantyne D

138,. 139,211 Riddoch G, Head H 160,

211 Riddoch G, see Head H 160,

206 Rieckmann C, see Blumberg H

129,133,135,136, 140, 141,142, 143,204

Riedel W, see Gregor M 130, 133,146, 155,206

Riedel W, see Peter W 155, 211

Rink TJ, see Marban E 32, 33, 44, 68

Rink TJ, see Tsien RY 35, 44, 71

Rioch DMcK, see Bard P 152,203

RobertsWJ, Elardo SM 158, 211

Roberts W J, see Calof AL 156,204

Roberts W J, see Pierce JP 157,211

Robertson SP, Potter JD, Rouslin W 32, 33, 70

Roche TE, see Lawlis VB 8, 9, 68

Roche TE, see Pettit FH 5, 70

Roddie IC, see Blair DA 193, 204

Rolleston FS 52, 70 Rosell S 159,211 Rosell S, Belfrage E 126,

159,211 Rossum GDV van, Smith KP,

Beeton P 27, 71 Roughton FJW, Chance B

83,116 Rouslin W, see Robertson SP

32, 33, 70 Routtenberg A, see Morgan

DG 49, 50, 69 Rovetto M J, see Neely JR

8, 69 Rowell LB 188,211 Rowe M, see Freeman B 157,

158, 205 Rubinstein EH, see Weissman

ML 136,142,213

Saccomanno G, see Kuntz A 175,209

Sachs AB 87, 116 Sachs AB, Lenchitz B, Noble

RL, Hess GP 80, 116 Sachs AB, see Hess GP 87,

106,107, 109, 110, 114 Sacktor B 12, 70 Sacktor B, see Carafoli E

60, 64 Sahs AL, Fulton JF 160,

211 Saito M, see Barker D 157,

203 Sakmann B, Adams PR 116 Sakmann B, Patlack J, Neher

E 116 Sakmann B, see Neher E 75,

105,106,116 Salzmann M, see Crompton M

15, 65 Sanctis N de, see Tedeschi RE

136,212 Santini M 157,211 Santini M, Ibata Y, Pappas GD

157,211 Sato A 212 Sato A, Schmidt RF 123,

197,212 Sato A, see Jgnig W 123,208 Scarpa A, Graziotti P 32, 33,

44, 70

Scarpa A, see Brinley FJ Jr 42, 64

Scarpa A, see DiPolo R 34, 65

Scarpa A, see Fisher AB 12, 66

Scarpa A, see Somlyo AP 24, 27, 31, 71

Scarpa A, see Vinogradov 27

Schainbaum J, see Tedeschi RE 136,212

Schell MA, see Huganir RL 112, 114

Schiff JD 157,212 Schirmann A, see Weiss L

58, 72 Sehl~ifke ME 137, 151,212 Schmid PG, see Abboud FM

155,202, 203 Schmidt RF, see J~inig W

123, 165,171,172, 173, 208

Schmidt RF, see Sato A 123, 197,212

Schnitzlein HN, see Eldred E 157,205

Sch6nung W, Wagner H, Simon E 155,212

Schoffeniels E, Nachmansohn D 75,116

Schoffeniels E, see Hess GP 106, 114

Schultzberg M, see H6kfelt T 154,207

Schwartz A, see Sumida M 83,117

Schwartz A, see V~ghy PL 49, 71

Sehwarze W, see Hess GP 106, 114

Schweitzer ES, Blaustein MP 42, 70

Scott ID, Akerman KEO, Nicholls DG 29, 30, 70

Scott ID, see Nicholls DG 42, 69

Scott MJ, see Daly MdeB 136,205

Seals JR, Czech MP 58, 70 Seals JR, see Jarett L 58, 67 Seidel W, see Golenhofen K

192, 193,206 Selincourt C De, see Brand

MD 39, 64 Seller H 171,212 Seller H, see Amendt K 198,

203 Seller H, see Dembowsky K

198,205 Seller H, see lllert M 198,

207

Author Index 225

Severson DL, Denton RM, Bridges B J, Randle PJ 58,70

Severson DL, Denton RM, Pask HT, Randle PJ 15, 7O

Severson DL, see Denton RM 6, 65

Severson D, see Randle PJ 5, 70

Shepherd JT, see Pelletier CL 142,211

Sheridan RE, Lester HA 116 Sherman S, see Tedeschi RE

136,212 Sherrington CS 121,212 Sherrington CS, see Langley

JN 125,151,176,209 Shimada M, see Sugano T

52,71 Shiota M, see Sugano T 52,

71 Shuchleib R, see Henry PD

25,66 Shuman EA, see Blackmore

PF 55, 63 Shuman H, see Somlyo AP

24, 25, 27, 31, 71 Sies H, Graf P, Crane D 51,

71 Siess EA, Brocks DG, Weiland

OH 51,52, 71 Sigel E, see Crompton M 15,

65 Silberstein RL, see Bulger JE

88, 91, 92,112 Silberstein R J, see Hess GP

91,114 Simon E 146, 165,212 Simon E, Iriki M 146,212 Simon E, see Iriki M 142,

207 Simon E, see Schtinung W

155,212 Skok VI 194,212 Skok VI, Ivanov AY 194,

212 Slater EC, see Haan EJ de 17,

65 Sloane B, see Somlyo AP 24,

31,71 Smith CM, Bry~ J, Williamson

JR 8,71 Smith KP, see Rossum GDV

van 27, 71 Snowdowne KW, see Borle AB

35, 63 Sobel BE, see Henry PD 25,

66 Somlyo AP, Somlyo AV,

Shuman H 24, 25, 31, 71

Somlyo AP, Somlyo AV, Shuman H, Scarpa A, Endo M, Inesi G 24, 27, 31, 71

Somlyo AP, Somlyo AV, Shuman H, Sloane B, ScarpaA 24, 31, 71

Somlyo AV, see Somlyo AP 24, 25, 27, 31, 71

Sommer O, see Bringer R 45, 46, 64

Sonnenschein RR, Weissmann ML 152,176,212

Sonnenschein RR, see Weissman ML 136, 142, 213

Spiel PF, see Barritt GJ 26, 63

Spilok N, see Jiinig W 129, 134, 159, 160, 163,164, 165,166,208

Spray DC 156,212 Spyer KM 195,197,199,

212 Spyer KM, see Hilton SM

122,207 Standish MM, see Bangham

AD 76, 77,112 Stansbie D, see Denton RM

6, 65 Steinman R, see Meijer AJ

10, 68 Stent GS, see Muller KJ 121,

210 Stevens CF, see Anderson CR

75,105,112 Stevens CF, see Neher E 77,

116 Strickland JH, Calhoun ML

125,151,212 Strickland WG, see Blackmore

PF 27, 63 Struve GE, see Hess GP 76,

77, 78, 80, 81, 92,114 Stucki JW, Ineichen A 15, 71 Studer RK, Borle AB 28, 71 Sugano T, Shiota M, Khono H,

Shimada M, Oshino N 52, 71

Sugden MC, Ball A J, Ilic V, Williamson DH 51,52, 57, 71

Sugden MC, Ball AJ, Williamson DH 51,52, 71

Sugiyama H, Popot JL, Cohen JB, Weber M, Changeux J-P 77,106, 116

Sugiyama H, see Popot J-L 77,106, 116

Sumida M, Wang T, Mandei F, Froehlich JP, Schwartz A 83,117

Sunderland S 156,212

Sundl6f G, Wallin BG 189, 190, 193,212

Sundl~f G, see Jiinig W 125, 127, 187, 196, 197,208

Sundl6f G, see Wallin BG 190, 213

Szulczyk P, see Blumberg H 129,133,135, 136, 140, 141,142, 143,204

Szulczyk P, see J~inig W 127, 128, 133, 171,172, 173, 178, 179, 180, 181,183, 198,208

Tager JM, see Akerboom TPM 7, 62

Tager JM, see Haan EJ de 17, 65

Tager JM, see Meer R van der 52,71

Tager JM, see Papa S 17, 69 Takeuchi T, Manning JW

154,212 Takeyasu K, see Hess GP

87,106,107,109,110, 114

Taylor EW, see Froehlich JP 83,113

Taylor EW, see Lymn RW 83,115

Taylor WM, Prpi6 V, Exton JH, Bygrave FL 54, 71

Taylor WM, Reinhart PH, Bygrave FL 52, 53, 71

Taylor WM, see Reinhart PH 52, 53, 54, 55, 56, 70

Tedeschi RE, Sherman S, Sanctis N de, Davidheiser S, Schainbaum J 136,212

Thiimer V, see Horeyseck G 123, 129,133, 153,154, 181,183,207

Thames MD, see Abboud FM 195,202

Thauer R 146,165,212 ThayerWS, Hinkle PC 83,

117 Thesleff S, see Katz B 77, 91,

92, 103,115 Thompson JW, see Kosterlitz

HW 179,209 Thompson JW, see Murray JG

170, 210 Tiffert T, see Brinley FJ Jr

42, 64 Tiffert T, see DiPolo R 34,

65 Toor HL 84,117 Torebj6rk HE, see Hagbarth

KE 190,206 Torebjtirk HE, see Hallin RG

188, 191

226 A u t h o r Index

Torebj6rk HE, see Marchettini P 192,210

Torebj6rk HE, see Vallbo AB 187,193,212

Tracy GD, Cockett FB 156, 212

Trzebski A, see Koepchen HP 122,209

Tsien RY, Pozzan T, Rink TJ 35, 44, 71

Tsien RY, see Marban E 32, 44, 68

Tsien RW, see Marban E 32, 33, 44, 68

Uhm DY, see Lee CO 32, 68 Uther JB, see Korner PI 136,

137,142,209 Uvn/isB 125,152,212 Uvn~is B, see Eliasson S 152,

205

V~ghy PL, Johnson JD, Matlib MA, Wang T, Schwartz A 49, 71

Veech RL, see Veloso D 15, 71

Vallbo AB, Hagbarth KE, Torebj6rk HE, Wallin BG 187, 193,212

Vanhoutte PM 147,213 Varma S, see Grewe W 129,

130, 133,147, 151,206 Veloso D, Guynn RW,

Oskarsson M, Veech RL 15, 71

Verjovski-Almeida S, Inesi G 83 ,117

Verjovski-Almeida S, see Kurzmack M 83,115

Vinogradov, Scarpa A 27

Wagner H, see Sch6nung W 155,212

Waisman DM, see Rasmussen H 25 ,44 ,70

Walajtys El, Gottesman DP, winiamson JR 15, 72

Walajtys-Rode E, see Pearse FJ 45, 70

Walker JW, McNamee MG, Pasquale E, Cash D J, Hess GP 87 ,111 ,117

Walker JW, see Hess GP 87, 106, 107, 109, 110,114

Wallin BG 190, 191,193, 213

WaUin BG, Eckberg DL 190, 213

Wallin BG, K6nig U 187,213 Wallin BG, Sundl6f G, Delius

W 190, 213

Wallin BG, seeB~th 13 190, 203

Wallin BG, see Bini G 188, 190, 191,192, 193,203, 204

Wallin BG, see Delius W 189, 191,205

WaUin BG, see Hagbarth KE 190, 206

Wallin BG, see J~inig W 125, 127 ,187 ,196 ,197 ,208

Wallin BG, see Sundl6f G 189, 190, 193,212

Wallin BG, see Vallbo AB 187,193,212

Wallis DI, see Kosterlitz HW 179,209

Walther OE, see Iriki M 142, 207

Wang GH 165,213 Wang GH,Chun RWS 151,

213 Wang T, see Sumida M 83,

117 Wang T, see V~ghy PL 49, 71 Watkins JC, see Bangham AD

76, 77,112 Webb-Peploe MM, see Brender

D 140, 204 Weber M, see Sugiyama H 77,

106,116 Weiss ES, see Henry PD 25,

66 Weiss L, L6ffler G, Schirmann

A, Wieland O 58, 72 Weissman ML, Rubinstein EH,

Sonnenschein RR 136, 142,213

Weissmann ML, see Sonnenschein RR 152, 176,212

Wendt-Gallitelli MF, Jacob R 24, 72

Wennergren G 136,140, 213 Wennergren G, see Kendrick E

136, 140, 141,209 Wernette ME, Ochs RS, Lardy

HA 12 ,13 ,72 Whitehouse S, see Denton RM

6, 65 Whiting JA, Barritt GJ 57,

72 Wiedersatz G, see J~inig W

125 ,127 ,166 ,187 ,196 , 197,208

Wieland OH 4, 45, 72 Wieland OH, see Patzelt C

57, 69 Wieland OH, see Siess EA 51,

52, 71 Wieland O, see Weiss L 58,

72

Wier WG, see Blinks JR 32, 63

Wiesenfeld-Hallin Z, see Hallin RG 157, 158,206

Wigston D J, see Purves D 196,211

Williams GR, see Chance B 3, 59, 60, 64

Williamson DH, see Sugden MC 51 ,52 ,57 , 71

Williamson JR 8,46, 72 Williamson JR, Cooper RH

29, 72 Williamson JR, Murphy E

21, 34, 72 Williamson JR, Cooper RH,

Hock JB 54, 72 Williamson JR, see Coil KE

21, 23, 24, 28, 29, 30, 31, 36, 37, 41, 53, 54, 55, 64

Williamson JR, see Fisher AB 12, 66

Williamson JR, see IUingworth JA 8 , 9 , 4 5 , 6 7

Williamson JR, see Joseph SK 27, 28, 29, 39, 40, 41, 44, 54, 56, 6 7

Williamson JR, see Meijer AJ 10, 68

Williamson JR, see Murphy E 21, 23, 27, 28, 29, 34, 35, 53, 54, 55, 56, 69

Williamson JR, see Pearse FJ 45, 70

WiUiamson JR, see Smith CM 8, 71

Williamson JR, see Walajtys El 15,72

Wilson DF, Owen CS, Holian A 52,72

Wilson DF, see Nishiki K 9, 69

Wiprich L, see Gregor M 129, 133, 135,136, 140, 141, 147,206

Wiprich L, see J ~ i g W 133, 138, 139, 148, 151,208

Woerkom GM van, see Meijer AJ 10, 68

Wolthuis RA, Bergman SA, Nicogossian AE 190, 213

Wonnaeott S, Marchbanks RM, FiolC 31,72

Wu CW, see Hammes GG 113

Wurster RD, see Barman SM 198,203

Wurster RD, see Foreman RD 198,205

Wyszogrodski I, see Polosa C 171,211

A u t h o r I n d e x 227

Xu H, see Bell C 154, 155, 2O3

Xu H, see Kiimmel H 161, 162, 164,166,209

Yaffe S, see Biinger R 45, 46, 64

Yip AT, see Giorgio NA Jr 6, 66

YipBP, see Babcock DF 53, 63

Zanchetti A, Baccelli G, Mancia G, EUison GD 153,213

Zanchetti A, see Ellison GD 153,205

Zanchetti A, see Mancia G 153,210

Zbrozyna AW, see Abrahams VC 152,203

Zimmermann M, see Beck PW 166,203

Zimmermann M, see Jiinig W 165,208

Zoccarato F, Nicholls D 41, 44, 72

Zuurendonk PF, see Akerboom TPM 7, 62

Subject Index

ace ty l cho l ine 76, 7 7 , 1 0 1 , 1 0 5 , 1 0 6 - - induced ion f luxes 76ff. - r ecep tor , see also r ecep to r

dens i ty 75 e x t r a s y n a p t i c and synap t i c 111 genera l m o d e l 74 ion channels , s ta t i s t ica l m e t h o d s 105

t r ans loca t ion 74 l igand b ind ing 92 p roper t i e s 91 p ro te in , r ad ioac t ive label l ing 75

- - , reviews on 74 - synthes is 50 [ ace ty l l / [CoASH] ra t io 60 ace ty l -CoA/CoASH rat io , m i t o c h o n d r i a l 50 ad ipose t i ssue 58 ADP, avai lab i l i ty 59

, con t ro l o f ca tabo l i sm by 3 adrena l ine 1 9 2 , 1 9 8 a t -adrenergic

agonis ts 34, 35, 51 , 52 , 54, 55 - , and Ca 44 - , i n t e r ac t i on w i t h 3-agonists on Ca 56,

57 3-adrenergic s t imu la t i on 46 , 49 , 55 a e q u o r i n 32, 33, 35 aging, Ca, and bra in f u n c t i o n 50 a l thes in 186, 187 anaes the t ics , e f fec ts on s y m p a t h e t i c neurones

1 8 5 , 1 8 6 a n t i p o r t sys tem, Ca2+/n Na ÷ 15, 16, 32, 49 an t ipor te r , e l e c t roneu t r a l 32 - , Na+/H ÷ 16 a rsenazo III 37, 38 a s p h y x i a 151 A T P / A D P ra t io 45 , 46, 49 , 50 ATP, cellular , dep l e t i on 55 - , homeos t a s i s 42 - synthes is 83 - - , free energy of 59 a t t e n t i o n 188 a x o n re f lex 144

ba ro recep to r e x c i t a t i o n 189, 190 - re f lex 1 9 5 , 1 9 8 - s t imu la t i on 129 ba ro recep to r s and s u d o m o t o n e u r o n e s 150 - , va socons t r i c to r e f fec ts 1 3 1 , 1 3 4 - 1 3 6 ,

1 4 0 - 1 4 2 , 1 6 7 behav iour , p i l o m o t o n e u r o n e s and 152

b l o o d f low, h u m a n , c u t a n e o u s and m u s c u l a r 192

- - , r ecord ing 129 , r egu la t ion 139 , s p o n t a n e o u s changes 192, 193 , venous in sk in 142

- vo lume , centra l , d i sp l acemen t of 190 b ra ins tem, descend ing p ro jec t ions 198, 199 a - b u n g a r o t o x i n 75, 77, 106, 107

, r ecep to r b ind ing 92 - sites, c o n c e n t r a t i o n 88

caf fe ine 32 ca lc ium a c c u m u l a t i o n , m i t o c h o n d r i a 34 - , ac t iv i ty coef f ic ien t , i n t r a m i t o c h o n d r i a l

36, 37, 54 - , a -adrenerg ic release 56 - a n t i p o r t e r 44 , 54 , 56 - - ca lmodu l in d e p e n d e n t enzymes 44 - - c h a n n e l a n t a g o n i s t s 46 , 48 - concen t r a t i on , cy toso l ic , buf fe r ing of 4 - - , con t ro l o f 36ff. - - - , free 3 , 5 0 - - - , in hea r t 32, 33 - - - , in p r e synap t i c t e rmina l s 33, 42 - - - , n e u r o n a l 33, 34, 42 - - - , t r ans ien t s in 33

m i t o c h o n d r i a l 36ff. - - - , free 3 - - - , m e a s u r e m e n t of 2 1 - 2 3

size o f 24 - c o n t e n t du r ing con t r ac t i on 32 - - , m i t o c h o n d r i a l 24ff. , 30, 45 , 54, 57 - - , - , exchangeab le 28 - , s y n a p t o s o m a l 31, 33, 42 - , con t ro l o f ca tabo l i sm by 3 - cycl ing, m i t o c h o n d r i a l 53, 57 - - , process energe t ics 2, 3 - d e s a t u r a t i o n s t u d i e s 30 - d i s t r i bu t ion , and a-agonis t s 55 - ef f lux, k ine t i c s of 3 6 - 4 1 - - , m i t o c h o n d r i a l 2, 3, 42ff . - E G T A c o m p l e x 32 - g rad ien t , m i t o c h o n d r i a l 18

, , phys io log ica l 17 - homeos tas i s , p l a sma m e m b r a n e in 41 - in f lux , depo la r i za t i on and 44 - - , p l a sma m e m b r a n e 43, 44 - , i n t r a m i t o c h o n d r i a l see also under

m i t o c h o n d r i a l - , " a c t i v i t y coe f f i c i en t " 36, 37, 54

S u b j e c t I n d e x 229

calcium, intramitochondrial buffering 30, 31, 39, 40

, inorganic phosphate 41 loss, a-agonist-induced 54

- , membrane cycling 15 - , mitochondrial , buffering 39, 40

, cycling 48 , efflux 40 , hormone action 4 3 , 4 4 , kinetics 53 , LTP 50 , on repetitive s t imulat ion 49

- /2Na ÷ antiport 15, 16, 3 2 , 4 9 - , plasma membrane permeabili ty 29, 42 - redistribution, cellular 54

- release, hormone-s t imulated 5 4 , 5 6 - - , measurements 56

- - , mitochondrial , inhibitor 27 - , sarcoplasmic ret iculum 55, 56 - -specific microelectrodes 32 - t ransport , ATP-driven 28 - - , mitochondrial 15, 16, 32, 34, 36ff.,

4 2 - 4 4 - uniporter 27, 32, 33, 34, 39, 4 2 - 4 4 , 50,

5 4 - 5 6 - uptake 5 6 , 5 7

, mitochondrial 46, 47, 50 , , reviews 2

and release, kinetic analysis 26 calmodulin 13 - Ca2+binding 44 cAMP 57 carbamoylcholine 76, 77, 9 3 - 9 6 , 99, 1 0 4 -

107 carbamoylphosphate synthetase 11, 12 capillary permeabili ty 159 cardiac rhythmici ty , sympathet ic 1 2 9 , 1 3 4 -

136, 140, 142, 161 ,172 , 189 ,192 - work performance 45 cardiovascular responses, adaptive 155 catecholamines, inot ropicresponse 33 causalgia 156 cell fract ionation 2 6 - 2 8

- respiration, control by ADP plus Ca 2÷ 3, 6 cesium and vesicle separation 87 channel-opening 102, 103

process, statistics 75 chemoreceptor reflex 198, 199 - st imulation 129 ,155 chemoreceptors , and sudomotoneurones 151 - , vasoconstrictor effects 132, 1 3 5 - 1 3 7 ,

142, 143 chloralose anaesthesia 148, 173, 185 ,186 ,

187 choline 77 colon, isovolumic contract ion 162, 164 ,166 conduct ion velocity, sympathet ic neurones

177ff. contractile force 46, 47 contracture 33 cutaneous see also skin

- nerve lesions 142

sympathet ic fibres 184 - receptors, s t imulation 143ff.

- - , sudomotor actions 149, 150, 165 ,166 , 192

- - , vasoconstrictor effects 132, 1 3 7 , 1 4 3 - 145 ,161

cytochrome c 59, 60

decerebration 185 ,199 defence area, hypotha lamic 125 ,152 , 153 - reaction 125 ,152 dehydrogenase see also under specific designa-

tions - activation by Ca 2÷ 41 - and mitochondrial t o t a lCa 21ff. - , Ca 2÷ control 28, 29 - , Ca 2÷ in intact mi tochondr ia 1 3 - 2 4 - , Ca 2÷ modula t ion 41 - , Ca2÷-sensitive 4-13

, , hepatic 51ff. , , s t imulat ion by hormones 57, 58

- control by Ca 35 - inactivation 42 - , kinetics and Ca 2÷ 19ff. - level control, biological advantages of 59,

60 - modula t ion by Ca 2÷ 29, 30

o f Ca 2÷ 37 - , NAD-isocitrate 60 - regulation and cytoplasmic Ca 31ff.

by Ca 2÷, physiology of 45ff. - - , m o d e l o f 30 ,31 - a n d S r a+ 6 , 8 dephosphoenzyme 4 depolarization and Ca 30, 42 descending control, sympathet ic units 199 dibucaine 5 4 dichloroacetate 50 digitonin 28, 2 9 , 5 4 diltiazem 48, 49 dissociation constant 89 dopamine 155 dyst rophy, reflex sympathet ic 156

electric organ see electroplax electron-probe X-ray microanalysis 24, 25,

27, 30, 31, 49 electroplax, bioelectric phenomena 75, 77 - cells and vesicles 106 - , comparison o f cells with vesicles 77, 85 - , E. electricus 106, 110 - , various, differences between 110 - , membrane vesicles 74ff. - , vesicles f rom different types 87

, , number o f receptor sites 105 ,106 - , Torpedo 106 emission spectroscopy 88 emotional states 1 7 3 , 1 8 8 , 1 9 1 , 1 9 2 energy demands, cellular 42 enteroceptors, sudomotor reflexes 150, 151,

166 enzyme activity, moni tor ing 20

230 S u b j e c t I n d e x

systems, quench flow techniques 83 enzymes, anabolic, mitochondrial and Ca 2÷

11, 12 - , catabolic, mitochondrial and Ca 2÷ 3ff., 12 - , intramitochondrial, Ca 2÷ sensitivity 13ff. epinephrine 35, 46, 48, 49, 51, 57 equilibrium constants 89, 91 ,103

- , evaluation of 92ff. erector pili muscles 125,129, 151

fat cell innervation 126 fatty acid oxidation 51, 52 - acids, #-oxidation of and Ca 2÷ 11 fractionation studies 52, 53 - - , mitochondrialCa 27 free fatty acids 159

glucagon 55, 57 glutamate dehydrogenase equilibrium 45 glutamate oxidation 17, 19 glycerol 3-phosphate dehydrogenase and Ca 2÷

12, 13 grey rami 175 guanethidine 154

H ÷ see proton hair follicle stimulation 129 hairy skin, vasoconstrictors 141 halothane 186, 187 heart, #-agonists and Ca 46ff. - cycle, intraceUular Ca 44 - mitochondria 30, 31, 36ff. hepatocytes 51ff. - , Ca 27, 28, 30 - , cytosolic Ca 34 hexamethonium 154 Hill coefficient 107 hippocampus slice 49, 50 histrionicotoxin 106 homeostasis 121 hormone action and Ca 2÷ 3, 7, 54, 55 horse radish peroxidase 174, 177 #-hydroxybutyrate/acetoacetate ratio 52 3-hydroxybutyrate oxidation and Ca 2÷

11 hypercapnia 137, -139, 147,150, 151 hyperesthesia 156 hyperhidrosis 188, 192 hyperventilation 191 hypothalamus 140, 167, 198 - , anterior, temperature sensitivity 146,

147 hypoventilation 138, 139,148 hypoxia 137, 142, 150, 173

inactivation rate coefficient 111 insect flight muscle 59, 60 insulin 58 ion channel statistics 75 - efflux, carbamoylcholine-induced 77, 81 - flux, acetylcholine-receptor controlled

76ff., 92

, minimal mechanism for 102- 105,110

kinetics, acetylcholine receptor 74, 75, 76ff.

in membrane vesicles 76ff. rate constants 91, 99, 100, 108

, evaluation of 92ff., 110 - - , relation to ligand-binding 90, 91 - influx, acetylcholine-receptor meadiated

98,101 rate, high, measurement 107, 108

- translocation, chemical kinetics and patch clamp 106

- - , receptor controlled 106 - - , minimal mechanism 110

process, model 103 - - , rate 8 8 - 9 0

- , reaction rate 90 - - , per receptor site 107 ionophore A23187 15, 23, 37, 39, 46 ionophores 56 isocitrate oxidation 17 isomerization rate constants 96, 97, 111 isoproterenol 46, 47

ketamine 186, 187 c~-ketoacid dehydrogenase and Ca 2÷ 10 kidney, cytosolic Ca 34, 35 kinase 4, 10 kinetic measurements, chemical 103 - scheme for receptor mediated ion flux

102, 103 - studies, Ca desaturation 27 kinetics, first order 102, 108

lanthanum ions 27 ligand binding 103

measurements 105 limbic system 173 ,185 ,191 lipolysis 159 liver dehydrogenase, stimulation 51ft. long term potentiation 49, 50 Loven reflex 144,191 lymphocytes, cytosolic Ca 2÷ 44

magnesium 15 - isocitrate 6 mechanoreceptors, sympathetic stimulation

157 membrane, ion translocation process 74, 75,

76ff. - potential, mitochondrial 50 - vesicles, desensitization 7 7 - 7 9

, different type of 78ff. - - , electroplax 74, 76ff., 87ff. - - , isolation of, receptor bearing ones 8 5 -

87 , kinetic properties 87 , leaky 77, 80

- - , purified, characterization of 87ff. , receptor function 75 , reviews 75

Subject Index

methohexital 186, 187 microneurography in humans 187, 188 mitochondria, adipose tissue 17, 18 - brain 18, 29 - Ca 2+ and function 3

buffering by 38, 39 content in situ 24ff. depleted 23

- cardiac 14,-18, 22, 24, 25 - energy transduction in 3 - hepatic 17, 18, 22, 24, 26ff. - ionophore-treated 15 - in muscle 18, 24 - , pathology 33 - , renal 18, 26ff. - , substrate oxidation 18 motor unit, functional 121,124 movement, regulation 199 muscle, insect flight 12 - nerves, sympathetic fibres in 184 - spindle, sympathetic control 157 - work 191

and mitochondrial enzymes 8

Na÷/Ca 2÷ antiport 58 Na + efflux measurements 107 - and mitochondrialCa 49-50 - permeability 76 NAD 59, 60 - , mitochondrial 8, 11, 16, 18, 19 NADH, end-product inhibition 60 - , mitochondrial, fluorescence 15, 20 NAD /NAD ÷ ratio 45,46, 49, 52 NAD-isocitrate dehydrogenase and Ca 2÷ 5 - 7

and nucleotides 6 negative pressure, lower body 190 nerves, artificial connections - , peripheral, fibre composition 174

, , numbers of sympathetic axons 184 nervous tissue, Ca content 33, 34 - - , mitochondria, Ca content of 29, 30 neural unit 196 neuronal organization, sympathetic, analysis of

121 neurotransmitter synthesis 50, 60 nictitating membrane 170, 178, 179 nociceptive reflexes, anaesthesia 186

, spatial organization 163 , after spinalization 160, 163,169 , sudomotor 150, 166 , sympathetic 137,144, 145,150, 152,

160,167 nociceptors, sensitization of 166 - , responses to sympathetic stimulation 158 - , stimulation 129 noradrenaline 198 "null-point" method 21-23, 34, 39, 53 - studies 36

oleate oxidation 51 oligomycin 55 02 uptake, hepatic 52, 53

231

oxidation, Ca =* sensitivity 35 2-oxoglutarate dehydrogenase 25, 31, 35, 37,

49 ,51 ,52 ,57 - - , allosterie activator of 52

, C a ~ ÷ 5 , 8 , 9

- - , NADH inhibition 8, 9 , nucleotides 8, 9

- , state-3 oxidation 17

Pacinian corpuscles 143, 149, 157, 165,167, 172, 189, 192

, stimulation 129 pad, innervation 165 pain 156 paraplegia 162 patch clamp technique 105 pelvic visceral afferent fibres 145 phentolamine 193 phenylephrine 51,52, 54-57 phosphatase activity and Ca 2÷ 4-6 , 10 - , changein 58 phosphate, and Ca buffering 41 phospholipases, activation of 11 phosphorylase a 34, 35, 39, 40, 46, 47, 53 phosphorylation, oxidative 59 piloerection 125,151,152, 170 pilomotoneurones 125,126 - , properties 151 - , reflexes 151,152 pituitary slices 30 postganglionic see also under sympathetic, and

under the various types of p. neurones postganglionic axons, conduction velocities

177, 181-183 - innervation, skin 188 - somata, segmentaliocation 174, 175 - sympathetic neurones, cutaneous 154ff. - - - , discharges, comparison of humans

with cats 187ff. functional classification 167-170

identification 187, 188 labelling of 169, 170

hypothalamic control 167 muscular 152-154, 156ff. numbers in nerves 183, 184 reaction patterns 167-169 reflex patterns, spinal 134, 159ff.,

169 186 specificity 169

silent 188 single, target effect 169 spatial organization 174,175,

177 - - - , spinal thermal input 167 - - - , subcutaneous 158,159 - - - , warm-sensivitve 155 preganglionic axons, specificity in efferent

connections 170ff. , unmyelinated 173

- neurones, cardiovascular, descending pathways 199

, conduction velocities 179

232 S u b j e c t I n d e x

, convergence onto postganglionic neurones 168, 179, 180

, distribution 171 - - funct ional ident i f ica t ion 171 ,172 , 179 - - hypothalamic control 173 - - reflex patterns 1 7 0 - 1 7 3 , 1 7 9 - - resting activity 171 - - segmental distribution 1 7 5 - 1 7 7 - - silent 172, 173 ,179 , 180 - - spinal location 177

synaptic connect ions 194 - sympathet ic outflow, spatial organization

170, 176, 177 presynaptic terminals, Ca content 30 primary afferents, conduct ion velocity 181,

182 - - , sympathet ic activation 1 5 6 - 1 5 8 proton extrusion 55

- gradient 23 - ionophores 28 - -motive force 59 - sympor t 26 pulmonary stretch receptors 139 pupillary dilation 170, 178 pyruvate carboxylase 11, 12 - dehydrogenase 4, 14, 15 - - in adipose tissue 58 - - , cardiac 45ff. - - , hepatic 51f f . ,57

- - , interconversion 17, 24, 25, 31, 37, 4 5 - 4 7 , 5 7

kinase 4, 6 and LTP 50

- - , neuronal 49, 50 phosphate phosphatase 35 and synaptic transmission 49, 50

quench flow apparatus 82, 94 - - , kinetic measurements 88ff.

- techniques 8 2 - 8 4 , 87, 106, 107 ,111 Quin 2 44

- and Ca measurement 35

R~-inspiratory neurones 138 ,139 rate coefficient 8 9 - 9 1 , 92ff. , 108, 110 - constant for inactivation 91, 94ff. Rb ÷ efflux 92 - influx 98 ,100 , 107, 108 - , ion translocation rate 90 reactivation exper iments 96

- rate 103 receptor, active and inactive 92, 103 ,104 - , channe lopen ing processes 102, 103 - controlled ion flux, fast 83, 84

, heterogeneous vesicles 76ff. , separation from other flux 81,

82 - , cutaneous 156

, , vasoconstrictor effects 161 ,163 - desensitization 93 - inactivation 7 7 - 7 9 , 81, 9 3 - 9 6 , 100 ,103 ,

1 0 5 , 1 0 8 - 1 1 0

- - , second step 110 - isomerization 105 - , ligand binding 102 - , - dissociation constants 80 - , obscured ion flux 78, 79 - reactivation 96, 97 - sensitivity 78 - site, concentrat ion 101 recording technique, sympathet ic axons 127,

128 redox shuttle 12 reduction potentials 59 respiration, mitochondrial 33 respiratory chain 60 - modula t ion of vasoconstrictor activity

138, 139 ,147 - rhythmici ty 138, 189

, sudomotoneurones 151 - states 60 ret iculum, sarcoplasmic 55, 56 rubidium see Rb + ru then ium red 25, 28, 29, 46, 58

sarcoplasmic ret iculum 26 , calcium 3 9 , 4 2

- - , - uptake 83 second messenger 44, 45 sensory receptors, sympathet ic control 1 5 6 -

158 serotonin 198 single channel conductance 106

current recording 106 skin potential 128 - - , negative transient 148, 150, 165 ,169

- temperature 128, 129, 147 - - , f luctuat ions 164 - , thermal conductivi ty 142 smooth muscle, vascular 24, 30 sodium see Na ÷ somatosympathe t ic reflexes 123 spatial organization, nociceptive reflexes 150 spinal cord cooling 164 - - , temperature sensitivity 146, 147

- - , warming 155 - neuronal organization, analysis of 121 - shock, sympathet ic 159, 160, 166 - temperature, sympathet ic effects 164 squid axons 33, 34 suberyldicholine 106 succinate dehydrogenase 10, 11 - oxidat ion and Ca 2+ 10, 11 sudomotoneurones 1 2 4 - 1 2 6 , 148ff., 165ff. - in humans 191 - , res t ingaet ivi ty 131 ,134 , 148, 165 ,186 ,

191 - andVIP 154 sudomotor nociceptive reflex 150, 166

- reflex and spinalization 166 - reflexes, cutaneous 149, 150, 1 6 5 - 1 6 7 ,

192 - - , enteroceptive 150 - - , thermal 151

S u b j e c t I n d e x

sudomotor re f lexes , visceral 151 superior cervical ganglion 170, 171 sweat glands 148, 165 sympa thee tomy 156 sympathet ic actions during moto r activity 121 - activity, long-term f luctuat ions of, humans

193 - axons, electrophysiological identification

127 ,128 - func t iona lun i t s 124 ,193 - - - , spinal synaptic organization 196ff. - ganglia, spatial organization 1 7 4 - 1 7 7 - nerves 30 - neu ra lun i t s 122 - neurones, see also under subclassifications

and under pre-, postganglionic - - , discharge properties 124, 125 - - , funct ional ident i f ica t ion 1 2 3 , 1 2 4 , 1 2 7 ,

128 - - , hypo tha lamiccon t ro l 198 ,199 - - , postganglionic, reflex pat terns 130ft. ,

159ff. , , various types of 1 2 4 - 1 2 6

- - , pre- and postganglionic 122 - - , recording o f activity 127 ,128 - - , synapt icorganiza t ion 167 - reflexes 123 ,124 - - , anaesthesia 1 8 5 - 1 8 7 - - , intact neuraxis 130ff.

after spinalization 134 ,160f f . , 169, 186

- responses, recording from target organs 128 ,129

- system, animal versus h u m a n exper iments 187 ,188

- - , central organization of 194 - - , cholinergic and non-cholinergic processes

196 efferent channels 194 funct ion 121

- - hierarchical organization 196ff. pathophysiological states 188 reflex concept 122, 195ff. segmental and descending integration

197 ,198 - - , single fiber analysis 123, 127 - - , spinal organization 160 - - , s t imulat ion of afferents 129 - - , s tructure and funct ion 124, 125

uni tary concept 122 - units, funct ional spinal 124 ,196ff . synapt ic t ransmission and Ca 49 synaptosomes, mitochondrial Ca 29

temperature dependent postganglionic neurones 155

t e t r ame thy l ammon ium 77 tetraplegia 152 thermal s t imult ion, CNS 147 ,151 the rmodynamic driving force 59, 60 thermoreceptive neurones 130 thermoreceptors , spinal 130

2 3 3

thermoregulat ion 1 4 6 - 1 4 8 thermoregulatory responses 155 the rmosudomoto r reflexes 166 T1 + flux measurements 106, 107 t ransmit ter release 33 tr icarboxylate cycle 3, 8, 51 d-tubocurarine 77

uncoupling agent 39, 56 - - , releasable Ca 29

studies, Ca content 28, 29 uniport , electrogenic 15, 16 unmyel ina ted fibres, conduct ion velocity

182 urinary bladder, afferents 130 - - , contract ions 161, 162, 164, 166 - - , reflexes 1 4 5 , 1 5 0

181,

vascular bed, cutaneous, differential sym- pathetic regulation 142, 143

- smoo th muscle, and cold 147 vasoactive intestinal peptide 154 vasoconstrict ion 170 vasoconstr ictor neurones 1 2 3 - 1 2 6

- - , cutaneous, in humans 190, 191 - - - , reflex activation 140ff., 163, 164,

1~7 190 ' resting activity 131 ,140 , 163, 186,

, , thermal ref lexes 146, 147, 167, 191 - - , human , synchronized 193

to muscle 161 - - - , discharge pat tern 135

, reflex activation 131ft., 161ft. , resting activity 130, 131 ,134 , 161,

189 - - - , in humans 1 8 9 , 1 9 0 - - , reciprocal organization 167, 193 - - , respiratory modula t ion 138, 139, 147 vasodilation, non-cholinergic, non-adrenergic

154, 155 - reflex, h u m a n 191 vasodilator neurones 125 ,126 , 147, 193 - - , cholinergic 1 5 2 - 1 5 4 - - , cutaneous 154 ,155

to muscle 1 5 2 - 1 5 4 - - , warm-sensitive 155 vasopressin 51ft . , 57 vesicle heterogeneity, effects on receptor

controlled flux 79 - preparations, heterogeneous 76ff. vesicles, aggregation, state 80 - breakage of 84 - concentrat ion of tracer ions inside 92 - funct ional receptors 101 - influx measurements 80 - internal volume 8 8 , 9 0 - min imalk ine t i c scheme 102, 103, 110 - purification 107 - receptor densi ty 88

- tracer ion content 99 trapping 80