The light color zone is ident---

a. Ribosomeb. Chromatinc. Mitochondriad. Golgi area+

The following are compounds are the

a. Porphorophibiligonenb.c. Eurobilirugend.

The majority of the iron in an atom is found in astistuent of:

a. Hemoglobin+b. Hemosiderinc. Myoglobind. Transferrin

Name the function of the hexos monophosphate shunt in the erythrocyte is to

a. Regulate the level of 2,3-PtGb. Provide/ prevent reduce glutathione+,

maintains the oxygenationc. Prevent oxegation of hemoglobind. Prevent of the reduction of heme irone. Provide energy for maintenance

In order of hemoglobin to combine reversibly with oxygen the iron must be

a. Complex with haptoglobinb. Freely circulating in the cytoplasmc. Attached to transferrind. In the ferrous state+

Which disease have the tear-dropped shape with abnormal platelets

a. Hemolytic anemiab. Multiple myelomac. G-6-DP deficiencyd. Myeloid metaplasia+

The characteristic in erythrocyte in pernicious anemia:

a. Mircocyticb. Pherocyticc.d. Macrocytic +, due to impaired DNA synthesis

In the normal adult, the spleen acts as the site for:

a. Storage of rBCb. Production of RBCc. Synthesis of erythropoietind. Removal of imperfect and aging RBC+, major

site of the destruction of our old RBC

After the removal of red blood cells, form the circulation, hemoglobin is broken down into:

a. Iron, porphorin, and amino acidsb. Iron, protoporphorin, globin +, c. Heme, protoporphorin, and amino acidsd. Heme, hemosiderin, and globin

Heinz- bodies are:

a. Ready identified in b. Rarely found in G6-PD deficient erythrocytec. Associated with shrerocyted. Denatured hemoglobins and easily removed by

the spleen +

Hemolysis that is happening in aproximal nocturnal hemoglobinuria are --- is:

a. Temperature dependentb. Complement dependentc. Antibody associatedd. Caused by the RC defect +

Cells for the transport of oxygen and carbondioxide are

a. Erythrocytes+b. Granulocytesc. Lymphocytesd. Thrombocytes

Erythropoietin acts to

a. Shorten the action of the erythrocyteb. Stimulate rna synthesis of the erythoroid cells +c. Increase colony stimulating factors produces by

the B-lymphocytesd. decrease the release of marrow erythrocytes

what cell shape is most commonly assoc. with an increase with HCHC

a. teardrop cellsb. target cellsc. spherocytes +d. sickle cells

what if decrease ang HCHC, Hypo chromic

which of the following is most closely assoiciated with nomatic hemochromatosis (iron)

a. iron overload in tissues +b. target cellc. basophilic strippplingd. renin sideroblast

--end of Physiology---

A patient with polycythemia --- who is treated with by phlebotomy, is most likely, to develop a deficiency of:

a. iron +b. vit. B12c. folic acidd. erythropoietin

the DAT is often positive in

a. congenital hemolytic spherocytosisb. marsh hemoglc. acquired hemolytic anemia+d. thalassemia major

the anemia of chronic infection is characterized by

a. decrease iron stores in the reticuloid systemb. decrease in serum iron levels +, due to

macrophagesc. marcocytic erythrocytesd. increase serum iron binding capacity

factors commonly iinvovle in producing anemia in patient with chronic renal disease( problem in kidney include

a. marrow hypoplasiab. inadequate erythropoiesis+c. vit b 12 deficiencyd. increase erythropoietin production

hypoprolfiti population in the bone marrow in patients

a. infiltration of bone marrow by toxic waste product

b. decrease levels of circulating erythroipoietin +c. defection globin synthesisd. overcrowding of bone marrow space by

increase myeloid precursors

which of the following characteristics are common with hereditary spherocytosis, hederidarylymmphos and spherocytosis

a. autosomal dominant hereditaryb. rc membrane defect +c. positive DATd. measured platelet count

which of the following is most closely associated with iron defiency anemia

a. iron overloading tissuesb. target cellsc. Baophilicstripplingd. Chronic blood loss +

(ako )

Evidence indicates that the genetic defect in thalassemia usually results in

a. The production of abnormal globin chainsb. A quantitative deficiency in RNA resulting in

decrease globin chain production +c. A structural change in the heme portion of the

hemoglobind. An abnormality in the alpha or beta chain

binding or affinity

Anemia secondary to Euremia (decrease the number of RBC) is characteristically

a. Microcytic hypochromicb. Hemolyticc. Normocytic normochromic +d. Macrocytic

Which of the following sets are laboratory finding is consistent with the hemolytic anemia

a. Normal or slightly increase erythrocyte survival, normal osmotic fragility

b. Decrease erythrocyte survival, increase catabolise of heme +

c. Decrease serum lactate hydrogenase activity; normal catabolism of heme

d. Normal concentration of haptoglobin; marked hemoglobinuria

An enzyme deficiency is associated with moderate to severe hemolytic anemia after the patient is exposed to certain drugs and characterized by rc inclusion formed by the denatured hemoglobin is

a. Lactate hydrogenase deficiencyb. G6dp deficiency +c. Pyruvate kinase deficiencyd. Hexokinase deficiency

_---end of something—

--laboratory findings—

Which of the following technical factors will cause a decrease ESR

a. Gross hemolysisb. Small fibrinblast in the sample +c. Increase room temperatured. Tilting of the tube

Which of the RBC indices is a measure of the amount of hemoglobin in individual rbc

a. MCHCb. MCVc. HCTd. MHC+

the ESR can be falsely elevated by

a. Tilting the tube+b. Refrigerated bloodc. Air bubbles in the columnd. Specimen being too old

A RC about 5cm in diameter that stains bright red and shows no central parlor is a

a. Spherocyte+b. Leptocytec. Microcyted. Macrocyte

The presence of excessive rouleaux formation on a blood smears is often accompanied by an increase

a. Reticulocyte countb. Sedimentation rate+, ESr is always associated

with Roueac. Hematocritd. Erythrocyte count

The characteristic of peripheral blood morphologic in multiple myeloma

a. Cytotoxic T cellsb. Rouleaux formation+c. Spherocytocisd.

In polycythemia vera, the hemoglobin, hematocrit, and rc count and mass

a. Elevated +b. Decreasec. normal