research on chemical intermediates10.1007...corresponding author’s e-mail: [email protected];...

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Supplementary materials 1 Research on Chemical Intermediates An efficient, straightforward and catalyst free synthesis of medicinally important S-alkyl/benzyl dithiocarbamates under green conditions Ali Asadipour a , Zeynab Shams a , Khalil Eskandari,* a Mohammad-Hossein Moshafi b , Ehsan Faghih-Mirzaei, a Yaghoub Pourshojaei,* a,c a Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutics Research Center, Kerman University of Medical Sciences, Kerman, Iran b Department of Pharmaceutical Science, School of Pharmacy, Kerman University of Medical Science, Kerman, Iran c Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran Corresponding author’s e-mail: [email protected]; [email protected]

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Page 1: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

1

Research on Chemical Intermediates

An efficient, straightforward and catalyst free synthesis of medicinally

important S-alkyl/benzyl dithiocarbamates under green conditions

Ali Asadipour a, Zeynab Shams

a, Khalil Eskandari,*

a Mohammad-Hossein

Moshafi b, Ehsan Faghih-Mirzaei,

a Yaghoub Pourshojaei,*

a,c

a Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutics Research

Center, Kerman University of Medical Sciences, Kerman, Iran

b Department of Pharmaceutical Science, School of Pharmacy, Kerman University of Medical

Science, Kerman, Iran

c Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical

Sciences, Kerman, Iran

Corresponding author’s e-mail: [email protected]; [email protected]

Page 2: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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1H NMR spectrum of compound 4a

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13C NMR spectrum of compound 4a

Page 4: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

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FT-IR spectrum of compound 4a

Page 5: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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1H NMR spectrum of compound 4b

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Supplementary materials

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1H NMR spectrum (expanded) of compound 4b

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1H NMR spectrum(expanded) of compound 4b

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Supplementary materials

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13C NMR spectrum of compound 4b

Page 9: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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FT-IR spectrum of compound 4b

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Supplementary materials

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1H NMR spectrum of compound 4h

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Supplementary materials

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1H NMR spectrum (expanded) of compound 4h

Page 12: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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1H NMR spectrum (expanded) of compound 4h

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Supplementary materials

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13C NMR spectrum of compound 4h

Page 14: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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FT-IR spectrum of compound 4h

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1H NMR spectrum of compound 4i

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Supplementary materials

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1H NMR spectrum (expanded) of compound 4i

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Supplementary materials

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13C NMR spectrum of compound 4i

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Supplementary materials

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FT-IR spectrum of compound 4i

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Supplementary materials

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1H NMR spectrum of compound 4k

Page 20: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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13C NMR spectrum of compound 4k

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Supplementary materials

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FT-IR spectrum of compound 4k

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Supplementary materials

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1H NMR spectrum of compound 4l

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Supplementary materials

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1H NMR spectrum (expanded) of compound 4l

Page 24: Research on Chemical Intermediates10.1007...Corresponding author’s e-mail: y.pourshoja@kmu.ac.ir; khalileskandari@yahoo.com Supplementary materials 2 1H NMR spectrum of compound

Supplementary materials

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1H NMR spectrum (expanded) of compound 4l

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Supplementary materials

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13C NMR spectrum of compound 4l

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Supplementary materials

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FT-IR spectrum of compound 4l

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1H NMR spectrum of compound 4n

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1H NMR spectrum (expanded) of compound 4n

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Supplementary materials

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13C NMR spectrum of compound 4n

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FT-IR spectrum of compound 4n