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Page 1: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function
Page 2: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

ReishiMax™ GLp contains the highest level of activesavailable

Standardized to:6% Triterpenes

13.5% Polysaccharides

Contains a 1% extract of 100% proprietary cracked spores

Contains naturally occurring:nucleosides, proteins and amino acids

unsaturated fatty acidsvitamins and minerals

Page 3: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

ReishiMax™ GLp is shown to:

stimulate the formation of antibodies

stimulate the proliferationof immune cells

modulate the function ofT-cells

ReishiMax™ GLp is for long-term use by adults who want to promote and maintain a healthy immune system

Page 4: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Reishi (Ganoderma lucidum) mushroom is a fungus occurring on the sides of trees and stumps in densely wooded mountains of southeast China.

Growing conditions of Reishi

• low light• very humid environment

These conditions also allow bacteria and other invaders to flourish

Page 5: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Types of Reishi

There are 62 types of Reishi, of which six are most common:

RED BLACKBLUE WHITE

YELLOW PURPLE

RED Reishi is preferred because it can produce the highest quality extract and has been subject to the most scientific evaluation

Page 6: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Cultivation of ReishiIn 1971, Yukio Naoi, a researcher of the Kyoto

University in Japan, successfully developed the artificial cultivation of Reishi, which resulted in reproducible and consistent production of Reishi.

Page 7: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Reishi Growing Process

1. Reishi body

2. Basidiomycete produces sporidium

3. Mycelium

1

23

Zoom in of Reishi body

Growth of Basidiomycete

Page 8: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

• These highly active substances are the essence of Reishi

• They are the reproductive cells that are released at maturity

• Reishi spores are protected by an extremely hard shell which prevent us from optimally absorbing the actives

Page 9: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

The most potent of Reishi’s ingredients are locked in seed-like spores

The unseen microscopic oval spores come from the top of the mushroom at maturity (4-5 months of cultivation)

Page 10: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

The “Cracked Spore” technology softens and breaks open the shell of Reishi spores, so that the potent active ingredients can be extracted

Cracked Spores Unlock Active Compounds

Page 11: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

大自然的馈赠 科学的验证Pharmanex 6S Process

Selection 精选

Sourcing 来源

Structure 结构

Standardization 标准化

Safety 安全性

Substantiation 疗效证实

Page 12: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Reishi Mushroom

Ancient Chinese recognized health benefits of Reishi mushroom: enhancing our body’s natural resistance and physical well being, resulting in optimum health and longevity. The records of medicinal use of this herb can be traced back to >2000 years ago:

“Li Ji”(300 BC)“Lv Shi Chun Qiu”(239 BC)“Materia Medica Classics of Shenhnong”(200 BC)“Ben Cao Gan Mu”(1300 AD)

Page 13: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

The Elixir for Longevity - Reishi长生健体之仙草 – 灵芝

Lingzhi was ranked the top and most valuable in the premium herb category. 灵芝被列为是珍贵药草中最具价值的顶级产品

The premium herb-elixir is mainly for strengthening of body performance, replenishing energy, prevention of aging. 此珍贵长生不老药草主要是增强体能、补充活力及防止老化

Page 14: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Selection 精选

Red Reishi scientific achievements since 1980’s

• Cell support• Immune support• Liver protection• Nervous system support• Cardiovascular protection and

blood sugar support

Page 15: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

♦The best Reishi cultivation method: solid tree trunk, organic cultivation

♦Free of pesticides and heavy metals, and no unwanted microbial contamination

ReishiMax Sourcing

♦ The best Reishi species: RED Reishi (Ganodermalucidum)

Page 16: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

100% Cracked Reishi Spores

100% 破壁灵芝

3000X magnification under an electronic microscope

Structure 结构

Page 17: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Use of Pharmanex’proprietarymanufacturing process to extract Reishi active components

专有多步骤萃取程序

Standardization 标准化

Page 18: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

• Standardized to– 6% triterpenes 三萜类

–13.5% polysaccharides 多糖体

Reishi Extract +

100% CrackedReishi Spores

Page 19: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Safety 安全性

Free of pesticides and heavy metals, and no unwantedmicrobial contamination没有农药,重金属的污染

Systematic toxicological examinations proved its safety 通过了系统的安全性检验

Page 20: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Placebo 0.585 1.170Reishi extract

2.9250

1000

2000

3000

4000

5000

Inte

rleuk

in-2

(pg/

ml)

p<0.001 by ANOVA

+405%

+822% +799%

By Medical Institute at National Taiwan University 国立台湾大学医学院

Reishi enhances immune functionsReishi enhances immune functions灵芝灵芝增强免疫增强免疫

Substantiation 实证

Page 21: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Third Party, New FindingsThird Party, New FindingsDaniel Silva, PhD, Miroslav Sedlak, PhD.; Veronika Slivova, BS, Tatiana Valachovicova, BS, Frank P. Lloyd, Jr., M.D., and Nancy W.Y.Ho, PhDCancer Research Laboratory, Methodist Research Institute, Clarian Health Partners Inc., Indianapolis, IN.Department of Medicine, School of Medicine, Indiana University, Indianapolis, IN.Laboratory of Renewable Resources Engineering, Purdue University, West Lafayette, IN.

Sliva,et al., J. Altern. Compl. Medicine 2003, 9(4):491-497

Page 22: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

The unique ReishiMax polysaccharides are responsible for immuno-modulating activities

ReishiMax Contains Unique Polysaccharides

Wang YY, et al. Bioorganic Med Chem 2002;10:1057-1062

Page 23: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

ReishiMax Health Benefits♦ ReishiMax maintains body’s

healthy immune system and modulates immune functions

♦ ReishiMax protects the liver♦ ReishiMax increases insulin

sensitivity and improves glucose metabolism

Page 24: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

• Promotes and enhances vital essence and energy

• Supports normal and restful sleep• Has an antioxidant effect• Helps in the maintenance or

improvement of general well-being

ReishiMax Health Benefits

Page 25: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

LianHe Wan Bao 20 June 2004

Page 26: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

ReishiMax Achievements• NUMBER 1 product in Taiwan!

• 2002 National Biotechnology-Medicine Quality Award by Taiwan government 获台湾行政院卫生署颁发健康食品许可证

• 2 Health Food Licenses awarded by Taiwan Department of Health 获台湾行政院卫生署颁发健康食品许可证 :

a. ReishiMax GLp for immune modulation获台湾行政院卫生署颁发健康食品许可证

b. ReishiMax GLp for liver protection获台湾行政院卫生署颁发健康食品许可证

Page 27: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Optimal Healthy Cell and Optimal Healthy Cell and Immunity ComboImmunity Combo

ReishiMax + Tegreen

Page 28: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Recommended UsageTake twice daily with meals:• 1 capsule each time for health

maintenance • 2 capsules each time for

immune modulationSafe and well tolerated at the recommended dosage

Page 29: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Recent PublicationsReishiMax GLp contains unique.Polysaccharides that are responsible.For immuno-modulating activities.

• Conducted by Pharmanex SAB member chi-Huey Wong at academia Sinica in Taiwan.

• Published: Wang YY, Wong CH, et al. Bioorganic & medicinal chemistry 2002;10:1057-1062.

Three new active compounds (lanostanoids) identified in Reishi.

• Conducted by Pharmanex scientists- J. Chang, M. Chang, and others.

• Published: ma J, ye Q, et al. Journal of natural products 2002;65(1):72-75.

Page 30: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Higher Solubility90%

71%

51%

0%10%20%30%40%50%60%70%80%90%

ReishiMax Reishi A Reishi B

By Pharmanex Research Center at Shanghai Medical University

Page 31: ReishiMax™ GLp contains the highest level of activesReishiMax™ GLp is shown to: stimulate the formation of antibodies stimulate the proliferation of immune cells modulate the function

Competitive Advantage

• 6S process• Best natural Red Reishi species• Organic cultivation• Cracked spores• Proprietary manufacturing

technology• Highest level of actives on the

market • Scientifically proven