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Registration Assessments 2014 Practice questions: March 2014

This set contains 10 practice questions.

Questions 1-5 are examples of questions from Open Book papers. The references that may be used are British National Formulary 67 March – September 2014 and BNF for Children 2013-2014.

Questions 6 -10 are examples of Closed Book questions.

There are 4 types of questions used in the Registration Assessment. Some practice sets contain examples of all 4 types, others do not.

A sample paper that is half the size of the actual Registration Assessment and shows all 4 types of questions and the proportion in which they are used within the assessment can be accessed at http://www.pharmacyregulation.org/education/pharmacist-pre-registration-training/trainees/registration-assessment/assessment

Copyright © General Pharmaceutical Council 2014. The content of this document is the property of the General Pharmaceutical Council and may not be reproduced.

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Directions for questions 1 to 4. For each numbered question select from the list above it the one lettered option which is most closely related to it. Within each group of questions each lettered option may be used once, more than once, or not at all. Questions 1 to 4 concern the following options: A a relatively minor adverse reaction which does not need to be

reported to the Medicines and Healthcare products Regulatory Agency (MHRA)

B a relatively minor adverse reaction which should be reported to the MHRA because the medicine is intensively monitored by the European Medicines Agency

C a relatively minor adverse reaction caused by an established medicine, which should be reported to the MHRA

D a serious adverse reaction which should be reported to the MHRA

E not an adverse reaction therefore it does not need to be reported to the MHRA

Select, from A to E, which one of the above is the most appropriate response for the following situations:

1. (open book)

a man who experiences nausea while taking azithromycin capsules

2. (open Book)

a woman who develops jaundice while taking sodium valproate tablets

3. (open book)

a man who experiences a fall in his LDL-cholesterol while taking atorvastatin tablets

4. (open book)

a woman who develops diarrhoea after receiving an infusion of belimumab

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Directions for question 5. The following question consists of a first statement in the left-hand column followed by a second statement in the right-hand column. Decide whether the first statement is true or false. Decide whether the second statement is true or false. Then choose:

A if both statements are true and the second statement is a correct explanation of the first statement

B if both statements are true but the second statement is NOT a correct

explanation of the first statement C if the first statement is true but the second statement is false D if the first statement is false but the second statement is true E if both statements are false

First Statement

Second Statement

Directions Summarised

A B C D E

True True True False False

True True False True False

2nd statement is a correct explanation of the first 2nd statement is NOT a correct explanation of the first

5. (open book) FIRST STATEMENT SECOND STATEMENT Four drops of Cipramil oral drops is approximately equivalent in therapeutic effect to one 20 mg Cipramil tablet

Cipramil oral drops contain citalopram hydrochloride 40 mg/mL

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Directions for questions 6 to 8. These questions are followed by five suggested

answers. Select the best answer.

6. (closed book)

A 40-year-old man comes into your pharmacy and asks if a proton pump inhibitor (PPI) would be suitable for him to try. He describes symptoms consistent with gastro-oesophageal reflux. Which one of the following symptoms would indicate that over the counter supply of a PPI would not be suitable?

A pain behind the sternum

B pain aggravated by bending over

C acid taste in the mouth

D dysphagia

E weight gain

7. (closed book)

Which one of the following antibiotics is the most appropriate for the treatment of Clostridium difficile associated diarrhoea?

A co-amoxiclav tablets

B co-trimoxazole tablets

C doxycycline capsules

D vancomycin capsules

E erythromycin tablets

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8. (closed book)

Mr W suffers from oesophageal cancer and is beginning to experience swallowing difficulties. He has significant pain from his cancer but it is well controlled on 60 mg morphine sulfate controlled release tablets every twelve hours. Given that he is finding the tablets increasingly difficult to swallow, but can manage liquids, which one of the following would provide the best alternative for Mr W?

A lidocaine 5% (700 mg/medicated plaster)

B BuTrans patches (buprenorphine) 5 micrograms/hour

C co-codamol 30/500 mg effervescent tablets

D ibuprofen 100 mg/5 mL oral suspension

E Durogesic DTrans ‘50’ (fentanyl patches 50 micrograms/hr)

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Directions for questions 9 and 10. Each of the questions or incomplete statements in this section is followed by three responses. For each question ONE or MORE of the responses is/are correct. Decide which of the responses is/are correct. Then choose: A if 1, 2 and 3 are correct B if 1 and 2 only are correct C if 2 and 3 only are correct D if 1 only is correct E if 3 only is correct

Directions Summarised

A

1, 2, 3

B

1, 2

only

C

2, 3

only

D

1

only

E

3

only

9. (closed book)

Which of the following is/are correct concerning insulin?

1 licensed preparations of insulin in the UK contain 10 units per mL insulin

2 insulin requirements are usually decreased by infection

3 insulin lispro (Humalog) has a shorter duration of action than insulin detemir (Levemir)

10. (closed book)

Which of the following statements about double-blind randomised-controlled trials is/are true?

1 neither the researchers nor the participants know which treatment has been allocated to each participant

2 participants are allocated to groups depending on baseline measurements

3 one group of participants will always receive a placebo