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Regional Innovation, Incubation Regional Innovation, Incubation and The University and The University Entrepreneurial Leadership and The Cambridge Model The Cambridge Phenomenon” The Cambridge Phenomenon” Professor Alan Barrell Hosei University, Tokyo February 26 th 2009

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Regional Innovation, Incubation and Regional Innovation, Incubation and The UniversityThe University

Entrepreneurial Leadership and The Cambridge Model

““The Cambridge Phenomenon”The Cambridge Phenomenon”

Professor Alan Barrell

Hosei University, Tokyo February 26th 2009

Context and Agenda

A General Context – A Changing World – A Financial Crisis Region and sub-region – where did the action really originate

QuestionQuestion - Is there optimal size / scale for optimal Innovative Development ?

Entrepreneurship as the driving force and Leader of much more than business success

Entrepreneurial mindsets and support structures Technology Transfer – The University did not lead A Family of Incubators under other names A Cluster of Creativity Characteristics of Successful Cambridge Incubators Recognising and building on serendipity Funding and Investment Readiness Preparation People, Diversity, Culture, Communities, Networking and

Society

Casting an Eye on the World’s Financial Crisis – What’s changed ?

Who said these words and When

“I believe the banking institutions are more dangerous to our liberties than standing armies. If the American people ever allow private banks to control the issue of their currency, first by inflation, then by deflation, the banks and corporations that will grow up around the banks will deprive the people of all property until their children wake up homeless on the continent their fathers conquered”

Who said these words and When

“I believe the banking institutions are more dangerous to our liberties than standing armies. If the American people ever allow private banks to control the issue of their currency, first by inflation, then by deflation, the banks and corporations that will grow up around the banks will deprive the people of all property until their children wake up homeless on the continent their fathers conquered”

Thomas Jefferson 1778

And what about these…

“The budget should be balanced, the Treasury should be replenished, Public debt should be reduced, the arrogance of officialdom should be tempered and controlled, and the assistance to foreign lands should be curtailed, lest our Nation become bankrupt. People must again learn to work, instead of living on public assistance”

And what about these…

“The budget should be balanced, the Treasury should be replenished, Public debt should be reduced, the arrogance of officialdom should be tempered and controlled, and the assistance to foreign lands should be curtailed, lest our Nation become bankrupt. People must again learn to work, instead of living on public assistance”

Marcus Cicero 55 BC

But - think BoomBoom ….not Gloom….many successful businesses startedstarted in

recessions….

“I started the Cobra Beer Company in a deep Recession – and it proved to be the best time for me….introducing something innovative and exciting changed the way people thought about Indian Food and Beer”

Lord Karan Bilimoria

Founder – Cobra Beer

But the eye on the World shows lotslots of changes….its not just the finances….and

some changes are permanent

The Changing Horizon

EnvironmentIssues

The death ofdeference

New employmentpatterns

Organisations

Globalisation

Technology

Sources of Competitiveness

Creativity Risk

Speed Reputation

Cost Values

Learning Information

Changes in Industrial Structure - UK% of Total Employment - UK Government Foresight Report 2001

0

10

20

30

40

50

60

70

80

90

100

1971 1981 1991 2001 2011

Manufacturing

All Services

Global Dynamics – Manufacturing has Migrated

Two fifths of the Worlds people live in the two fastest growing large economies – China and India

Education, Wealth Creation and New Knowledge are at the heart of Economic Planning in Asia

Growth in Asia is far ahead of Europe.

Dynamic Growth in Manufacturing Base

CASH is in place in the Asian economies – as well as brainpower- China has US$ 2 Trillions of reserves

Labour and Material cost advantages +++++

Cambridge and the Eastern RegionCambridge and the Eastern Region

Traditional IndustriesTraditional Industries

•Agriculture and FoodAgriculture and Food

•FishingFishing

•Leather goods - FootwearLeather goods - Footwear

•Wool and TextilesWool and Textiles

•7.5 million people7.5 million people

•One of UKs fastest growingOne of UKs fastest growing

•Region governed by EEDA – East of Region governed by EEDA – East of England Development Agency England Development Agency

Trinity College’s History and Scientific Development – Cambridge – Science, Innovation and Invention

Trinity always had a strong scientific tradition*

First use of the word “scientist” 1835 (Whewell)

First European Science Park – 1970 – Dr Sir John Bradfield

*Alumni include Newton, Clerk-Maxwell, Rayleigh, Thomson, Walton, Rutherford, Aston, Lyle, both Braggs, Bohr, Hopkins, Klug, Kendrew

Ramsey Chatteris Littleport

Mildenhall

Bury St Edmunds

Haverhill

Saffron WaldenRoyston

St Neots

Huntingdon

HUNTINGDONSHIRE

SOUTH CAMBRIDGESHIRE

CAMBRIDGE

NORTH HERTFORDSHIRE(PART)

ST EDMUNDSBURY(PART)

FOREST HEATH(PART)

EAST CAMBRIDGESHIRE

FENLAND(PART)A

1(M)

A14

M1

1A14

A10

A14

A11

A11

A10

UTTLESFORD(PART)

A10

A1

Greater Cambridge Partnership Area ( GCP) – one of nine “Sub-regional Development Partnerships”

in the EEDA – East of England Development Agency Region

2002 GC EstimatesPopulation: 750,000

Jobs: 359,000GVA: £12.2bn

Building an Enterprise Society. Power of Entrepreneurship, Innovation and Networking

Building communities of enterprise,social inclusion and

common purpose

Sub-regional development

Regional economic development

National economy

Cambridge in 1960 Medieval City Great University and Seat of Learning Farmers Not much Industry Lots of Bicycles Entrepreneurs? Entrepreneurship? – “Town

and Gown” – and Agriculture…. But things were changing….

Thinking About Entrepreneurship….Entrepreneurship….

And about Creativity,Creativity, Innovation, Innovation, Discovery Culture, and Mindset – Discovery Culture, and Mindset – Historical Perspectives…and TimingHistorical Perspectives…and Timing

Jules Verne – “There is nothing more “There is nothing more powerful than an idea whose time has powerful than an idea whose time has come”….come”….

And - With this background….Let’s IMAGINE

Einstein on IMAGINATION….

“Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world”

Albert Einstein 1879 - 1955

“You look at things and ask - why?

but I dream of things that never

were and ask -

George Bernard Shaw

why not?”

So - thinking of Imagination….What’s different about EntrepreneursEntrepreneurs ? ?

Europe’s Entrepreneurial Imperitive – Josef Schumpeter - 1911

“Entrepreneurs blow gales of creative destruction.”

Role of the entrepreneur in transforming economies by developing:

New products New methods of production New ways of organizing Untapped raw materials Enhanced competitive performance

Is The Cambridge Phenomenon an Is The Cambridge Phenomenon an Example of a Example of a “Mini-Schumpeter “Mini-Schumpeter Gale of Creative Destruction?”Gale of Creative Destruction?”

Entrepreneurship – The bigger picture….Leading Social Change

(Prof Shai Vyakarnam – Cambridge 2008)

Berlin WallHasselhof China

India MigrationsWithin and intoEurope

SingleEconomic system

Completely new marketsIs there a shift in

economic centre of gravity?

Add the Impact and Timing of the Continuous Technology Revolution….

Compared to an average DAY in 2003….

All international phone calls1971

All airline passengers1975

All mobile phones 1984

All emails 1992

All SMS1998

Source: Analysys, World Bank and ITU

Three Converging RevolutionsThree Pervasive Technology Platforms

BIO TECHPharmaceuticals

DiagnosticsResearch/Info

ToolsIndustrial

GenomicsBioinformatics

Proteomics

INFO TECHHardwareSoftware

Communications

NANO TECHElectricalStructural

BiomedicalEnergy & Environment

BiosensorsBiochipsBioelectronics

MicrofluidicsNanobiotechnology

Drug Delivery

NanodevicesNanosensors

Nanoelectronics

• Combined headcount of technology providers currently exceeds 2,500 in UK

• PA Technology employs up to 2,500 Worldwide

• Combined direct and indirect revenues estimated at $1,5 billions – ? more

• PA technology – Revenues $750millions+

• Some players have seed funds

• 70 identified spin-outs - highly successful incubator models

1960 – The “Columbus Spirit” hits Cambridge – and a Cluster emerges

The TechnologyPartnership

Scientific G enerics Sym bionics Team C onsulting P lextek

P .A. Technology

C am bridge C onsultants Ltd(1960)

C am bridge U niversity

From 1960 – Birth of the Worlds largest Industrial Ink Jet Cluster

Elmjet Ltd

1986

LinxPrinting

Technologies1986

Support to Imaje (France) formed 1979

XaarPrinting

Technologies1990

Cambridge Consultants Ltdspin-out 1960

Cambridge University

Domino Printing Sciences

1978

WillettInternational

Ltd1983

INCA Ltd

2000

• Total current revenues $1.5 billion +

• Total headcount 4,000+

• Major market share participation worldwide

• Diaspora populates Ink Jet Industries in international locations

• Ink Jet Cluster is enabling “Plastronics” Cluster. Revolution –

Plastic Logic – “E-Reader” – already raised $250 millions!

CCL 1960

Until 1985

1986-1990

1991-1995

1996-2000

2001-2002

PA1970

Gordon Edge

Collin SmithersPlextek

Scientific Generics

Gordon Edge, Bob Pettigrew

Pivotal Resources

Absolute Sensors

Sensopad Technologies

ImergeSphere Medical

3D Molecular Sciences

IonicaQuantumBEAM

Gordon Edge, Bob Pettigrew, Alan Green

Adaptive ScreeningFlying Null

Diomed Tony Raven

Sentec

Ubinetics

Andrew Dames

Andrew Dames

Acquired by Synaptics

Smartbead Technologies

PolatisHolotag

Caroline Garey

Andrew Dames

PreludeRobert Hook

Xaar

David PatonMike WillisSteve Temple

Mike Willis

Aphamosaic

Cambridge Silicon Radio

Cyan Technology

Pelikon

Roundpoint

INCA Digital Printers

ELMJET

Domino

DCS Cambridge Mass

Spectrometry

Bill BaxterWill EvePaul AnsonMike Payne

Graham MartinColin GrayWill Eve

Acquired by Videojet

Technologies

Graeme MintoDavid Paton

Xennia TechnologiesAlan Hudd

Transversal

David YipDavid McKay

Barrie GriffithsSteve Mullock Kore

Technology

Yuno Ltd

Steve BarlowRobert SwannPhil O’ Donovan

James CollierGlenn Collinson

Chris Davies

Acquired by Elumin founded by Dr. Hans Wagner

David Bending

Symbionics

Ali Pourtaheri

Dennis Fielder

Acquired by Cadence

Tality

Fen Technology

TTP

Gerald Avison

Adrian Lucas

Mark HowardRichard Doyle

Stuart Hendry Gavin Troughton

Elizabeth HillMark Tracy

Nigel Playford

WavedriverAcquired by PowerGen

TTP Ventures

TTP LabTechCreativity

Partnership

Acumen Bioscience

ip.access

Myriad

Acquired by Mettler-Toledo

Automation Partnership

Demerged from TTP Group

TTPCom

Chris FryerChris

Barnardo

Mike Storey

Cambridge Physical Sciences

Roger Millar

Signal Process Ltd

Robin Smith-Saville

VividStephen Eason

Acquired by Vetura

Radiant Networks

Mike Crossfield

Tony Milbourn

Tim Eiloart

Ross Green, Mike Kellaway

Richard Archer

John Cassells

Richard PhilpottJohn Cassells

David Cornell

Anne Miller

Figure 2 – The hi-tech start-ups spawned from the Cambridge ConsultantsTin Bustin, Ciaran McAleer

The emergence of high-technology clusters in Greater Cambridge

1971 1981 1991 2001 The future?

ScientificInstruments

Nanomaterials

Drugs delivery

Sensors/actuators

Informatics

Instrumentation

Medical engineering

LEPs

Drug modelling

Bluetooth

Sentient computing

Telecoms

Industrial inkjet

Biosciences

Computing

Software

ScientificInstruments

Wirelesscommunications

Telecoms

Industrial inkjet

Computing

Biosciences

Software

ScientificInstruments

Hi-tech 20,200 25,100 34,900 46,200jobs:

Computing

Software

ScientificInstruments

Industrial inkjet

1971 1981 1991 2001 The future?

ScientificInstruments

Nanomaterials

Drugs delivery

Sensors/actuators

Informatics

Instrumentation

Medical engineering

LEPs

Drug modelling

Bluetooth

Sentient computing

Telecoms

Industrial inkjet

Biosciences

Computing

Software

ScientificInstruments

Telecoms

Industrial inkjet

Biosciences

Computing

Software

ScientificInstruments

Wirelesscommunications

Telecoms

Industrial inkjet

Computing

Biosciences

Software

ScientificInstruments

Wirelesscommunications

Telecoms

Industrial inkjet

Computing

Biosciences

Software

ScientificInstruments

Hi-tech 20,200 25,100 34,900 46,200jobs:

Computing

Software

ScientificInstruments

Industrial inkjet

Computing

Software

ScientificInstruments

Industrial inkjet

50,000

Cambridge University

1960

1970

MRC Laboratory

of Molecular Biology

CADCentre

Sinclair Radionics

CCL

Barclays Bank

1980

Cambridge Interactive

System

Cambridge Science Park

Acorn

PA Technology

Eicon Research

Ltd

Sinclair Research Ltd

1990

Analysys

Olivetti Research Laboratory

(acquired by AT&T in 1999) Judge Institute of

Management Studies

St. John Innovation

Centre

Scientific Generics

The Technology Partnership

TTP

Cambridge Research and Innovation Ltd (CRIL)

Institute of Biotechnolog

y

Cantab Pharmaceuticals

Hitachi Cambridge Laboratory

Nickerson Biotech

Laboratory

Glaxo

2000

Toshiba Cambridge Research

Laboratory

Seiko Epson Research

Lab

Unilever Cambridge Centre for Molecular

InformaticsCambridge

Network

Institute of Manufacturing

Amadeus Capital Partners

TTP Ventures

Entropic Research Laboratory (acquired by Microsoft in 1999)

Glaxo Institute of Applied

Pharmacology

BP

Universities and centres of academic excellence Entrepreneurs with marketable ideas and products

Business angels and established seed funds

Sources of early stage venture capital

Core of successful large companies

Quality management teams and talent

Supportive infrastructure

Affordable space for growing businesses

Access to capital markets

Attractive living environment and accommodation

Social and Business Networks

source :- Gibbons - Stanford University 1998

Characteristics for High Technology Regions

As we get momentummomentum - Overlapping Technologies support Overlapping Business

Clusters

HEALTH

KNOWLEDGE CREATION

INFORMATION and COMMUNICATIONS

TECHNOLOGY

Basic Research

Sound & vision

Bio-pharmaceuticalsComputing

Publishing

Medicalservices

Bio-informatics

Medical devices and scientific instruments

University/ Research Institutes

Inkjet printing

Wireless

Telecoms

Networking

Technology ConsultingMedicalresearch

Education

Charles Darwin – “Natural Selection Adaptability and Survival” Darwin’s

Bicentenary this year

Natural Selection, Adaptation, Symbiosis Synergy Incubation and Cluster Development

And….We can apply the principle to companies…

Proximity of Learning, Research and Practical Application

“The Innovation Campus”

R&D Education

Applications

Where open innovation, symbiosis, synergy and new companies can thrive

Completing the Jigsaw – putting technology to work

TechnologyCustomer

need

Innovative service

company

Completing the Jigsaw – Service Delivery Innovation

TechnologyCustomer

need

Innovative service

company

Characteristics of Cambridge Incubators – IT, Bio. and

Generalist types all exist – in a Science Park, Innovation Centre and Incubator base

Research and Development and broad Technology skills base

Commercial orientation and focus Marketing, Finance and Management

capabilities in house Mentors and Advisors integrated Excellent Networking and Connectivity Flexible space availability and access

Funding Innovative Companies – “Show me the Money $$$$!”- The Funding Challenge

Maturity

Risk

“Our Money”“Our Money”

Family and Friends and FoolsFamily and Friends and Fools

Business AngelsBusiness Angels

Early Stage VCEarly Stage VC

Expansion CapitalExpansion Capital

B

A

N

K

F

I

N

A

N

C

E

??

Seed FundsSeed Funds

Pre-IPOPre-IPO

Thinking Of Angels! – How did Business Angels get that name ?

“Syndication Nodes” and Business Angels – Connecting in and from Cambridge

Cambridge has four active Angel Groups – Cambridge Angels, Cambridge Capital Group, Equus, G.Eastern Investment Forum

MOUs and Syndication with- Other UK Angels, Sophia Angels ( France) Luxembourg BAN, B.A.of Slovenia,US Angels Networked with all known, useful VCs and Grant bodies

Joint events, Deal and Portfolio Sharing Common Network and Portfolio Management -

Angelsoft Keeping well informed – eg. French Wealth Tax French Wealth Tax

changeschanges – Transformational impact. – Transformational impact. Strong International VC connections

Show me the MONEY! – So maybe we can we find Show me the MONEY! – So maybe we can we find investors hanging out here?....investors hanging out here?....

“How do we get to the money ? Where is the $$$$ trail ?” Connecting and Information

Points and Principles

Networks and Networking – importance +++++ Business Schools and Entrepreneurship Centres Region

wide and cross border Other Entrepreneurs / Support and Mentoring Structures Online Channels – numerous eg…. www.funded.com “Network Nodes” – Individual referrals Cross Border contacts Attitudes and Culture France and it’s Wealth Tax….Thank you M. Sarkosy !

The Early Stage Business Balance – what do investors look for? In ANY innovative

company ?

And they like to see experienced Chairman and Directors - Mentors for Innovative young Companies

Inspired Leadership

Enthusiasm

Bullshit

Courage

OptimismVision

Creativity

Management

Research & Analysis

Caution

Process

Financial Control

Market Knowledge

Today – “The Cambridge Phenomenon” – The University Embraces the Modern World –

Entrepreneurship in action More spin offs from University

research groups University people and ideas are

now at the core of many of the new technology ventures

University organisations have helped develop the infrastructure of the ‘cluster’ (eg, Trinity College and the Science Park; St John’s College and the Innovation Centre)

Cambridge has become a magnet for hi-tech and biotech companies – Silicon Fen

Academia, Business, Professional Services, Public Policy – working together

Business – University exchanges ++++

Entrepreneur Support and TheCentre for Entrepreneurial Learning (CfEL)

History:

1999 - Cambridge Entrepreneurship Centre (CEC)

2003 – Centre for Entrepreneurial Learning (CfEL) Run 40+ courses a year

CfEL Core Design Principles The best teachers are entrepreneurs

Real-life businesses and problem solving Focus on the practical

Action learning Development of own ideas Building confidence

The power of communication and networking Explore synergies and make practical connections Access to network

J udge Business School

Page 3

…at the heart of Cambridge University with global reach

Silicon Fen

Collegiate structure and learning

approach

Proximity to London, Europe’s corporate centre

Multi-disciplinary collaboration

Cambridge Judge

Distinction

Ethos and Values

Dr. Shai Vyakarnam

CfEL DirectorKatharine

Price

Yupar Myint

Dr. Jo Mills

Stew McTavish

How Do We Work? Curriculum development by CfEL Leverage external expertise to deliver – over 200

entrepreneurs and practitioners Highly customer focus Constant assessment on quality of programmes Build on reputation for excellence to create further growth

and expansion

Who’s Who - CfEL Team

Frances Bycroft

Orsi Ihasz

Peter Hiscocks(ACHIEVE)Arun Muthirulan

CfEL’s Entrepreneurs in Residence

Alan Barrell Library House

Phil O’ Donovan Camrivox

Alex van Someren

nCipher

Jack Lang Serial

Entrepreneur

Dan Roach Avlar Bioventures

Ann Cotton Camfed International

John SnyderGrapeshot

Richard Green Ubisense

Walter de BrouwerFounder

of Starlab

I want to learn...

What entrepreneurship is all about

Some new knowledge and skills in business planning

How to get my idea started

How to survive and grow in the early stages

How to develop and grow companies

How to teach entrepreneurship

I’m a CU student and want Entrepreneurship as part of my degree

Undergraduate and Postgraduate Assessed Programmes

I’m a student or member of staff or local entrepreneurial individual

Enterprise Tuesday(Term 1)

Enterprise Tuesday(Term 2)

I’m a student Enterprisers Ignite: ‘Fast Tracking Innovation’

I’m a Solo Entrepreneur with a technology idea

I’m a Corporate Intrapreneur or Entrepreneurial Manager

Senior Managers’ Programme

I’m an entrepreneur or an entrepreneurial academic

Summer Forum

CfEL’s ProgrammesCfEL’s Programmes

Graduate Programmes

MBA Chemistry Earth Science Graduate School of

Biological, Clinical, Medical and Veterinary Sciences

Undergraduate Programmes

Physics Chemical Engineering Materials Science Computer Science Biochemistry Architecture

Entrepreneurship Courses within the University of Cambridge

Emerging Technologies Entrepreneurship

Taking the journey – Amex, Microsoft, University Faculty

• Intensive one-week course for students, solo entrepreneurs and corporate innovators with technology/ knowledge ideas

• Focuses on developing a strategy for each participant’s new venture

• Tailored support to individual project needs through investment readiness, technical and market due diligence, mentoring and expert clinics

• Access to a network of valuable contacts and sources of investment - 100 contributors involved in delivering each programme

• Opportunity to pitch idea to a panel of investors, entrepreneurs and corporate venture heads

• Successful nine year track record!

88thth -14 July 2007 -14 July 2007 Cambridge Cambridge

Timetable 8Timetable 8thth to 14 to 14thth July 2007 July 2007

Research Projects at CfEL

•Role of Individuals•Social networks

•Entrepreneurial process of

innovation and venturing

•Role of Individuals•Social networks

•Entrepreneurial process of

innovation and venturing

What to each

•Enterprisers•Webcast

•Development Centres

•Enterprisers•Webcast

•Development Centres

How to teach

•Project with neuroscience•Intuition

•Included in sample at ARC

•Project with neuroscience•Intuition

•Included in sample at ARC

Born or made

Entrepreneurial Skills and Knowledge

Collaborative Research Projects:

• Analysis on Indivers’ entrepreneurial companies and resources (EFER, Netherlands)

• Centrality of Firm: Quantitative Analysis (JBS)

•Open Innovation with Unilever & Institute of Manufacturing

• Comparative analysis between Cambridge and Arezzo entrepreneurial clusters (University of Siena and University of Florence, Italy)

• Entrepreneurs - Born or Made (Prof Barbara Sahakian )

A significant feature of Cambridge cluster:

Highly Developed Social Networks of Entrepreneurs

“The majority of high technology companies that have shaped the success of Cambridge cluster are

connected to a handful of serial entrepreneurs, business angels and venture capitalists”

Research into importance of Entrepreneur Social Networks – and how they build them –

Myint and Vyakarnam

Until 1985

1986-1990

1991-1995

1996-2000

2001-2002

Cambridge University

AcornHermann Hauser

Acquired by Olivetti

Olivetti Research Lab

Andy Hopper

Adaptive Broadband

Cambridge BroadbandAcquired by American Microwave

Acquired by Western Multiplex Corp

Andy HopperPeter Warton

IPV (Telemedia Systems)

Andy Hopper

Virata(ATML)

Hermann HauserAndy Hopper

Merged with Globespan

Acquired by AT &T

RealVNCVirtual Network

Computing Level5NetworkAndy Hopper

ANTAlex van SomerenNicko van Someren

nCipherAlex van SomerenNicko van Someren

NetchannelHermann HauserJack Lang

Acquired by NTL

ARMElement 14

Stan BolandSimon Knowles

Acquired by Broadcom

Amadeus Capital PartnersHermann Hauser

IQ BioHermann Hauser, Chris Keightley

Part of DAKO Diagnostics

DakoCytomation - Merged with

Cytomation Inc

CDT

Richard Friend

Richard Friend Plastic Logic

Analysys

David Cleevely

Cambridge Network

David Cleevely Hermann HauserAlec Broers

Cambridge 3G

David Cleevely

CPSPeter Duffett-Smith

Polight Technologies

Stephen ElliottPavel Krecmer

ART

Daniel Hall

Pilgrim BeartActiveRF

Pilgrim Beart

Antenova

Zeus Technology

Adam TwissDavid Reeves

Cambridge Semiconductor

Gehan AmaratungaFlorin Udrea

MuscatJohn SnyderMartin Porter

Enterprise Accelerator

John Snyder

John SnyderWebtop

SmartlogikAcquired by Dialog

Small World

Richard GreenAuthur Chance

Dick Newell

CADShape Data

Charles Lang

Acquired by GE

TensailsRichard Green

VBN online

TerraPrise

Ubisense

Andy HopperSteve Pope

Andy HopperAndy WardPete Steggles Simon Elliott

David Cleevely

Electronic Share Information

Acquired by E* Trade

Hermann HauserJack Lang

Top express

Jack Lang

Splashpower

Lily ChangJames Hay

Saviso Group

Adam TwissBryan Amesbury

Innovia

Collin AgerGarraint Davies

Cambridge Interactive Systems

Hermann HauserMike MullerTudor BrownJamie Urquhart

Dick Newell, Tom Sancha

Figure 1 - The hi-tech start-ups associated with the Cambridge University

Stan BolandSimon Knowles

Icera

Laser-ScanR. O. Frisch

M-SpatialAdrian CuthbertJon Billing

Until 1985

1986-1990

1991-1995

1996-2000

2001-2002

AGC 1984

Alan Goodman

ATMAlan Goodman

Salix pharmaceutical

Alan Goodman

Peptide TherapeuticsNow Acambis

Daniel RoachAlan Goodman

AmuraAlan

Goodman

Avlar BioVenturesAlan Goodman

Daniel Roach

Oxford BimedicaAlan

Goodman

LiDCO

Alan Goodman

Terry O’Brien Alan Goodman

CORE

CeNes

Daniel RoachAlan Goodman

ChiroscienceChris Evans

Alan Goodman

Enzymatix

Chris Evans

Merged by Celltech

Group

Rapigene

ChiroTech

Enviros

Chris Evans Chris Evans

CerebrusToad

Chris Evans

Chris Evans Chris Evans

Merlin Ventures

Celsis

Amedis pharmaceutical

William Bains John Caldwell

Axis Genetcs Iain Cubitt

Iain CubittPestex Changed its name

to MicroBio Group

Acquired by Becker

Underwood

MRC LMB 1960s

Greg WinterDaivd Chiswell CAT

Greg Winter Diversys

RiboTargets

Simon Sturge

Celltech

Cambridge University

Martin Davies BioRobotics

Cantab Pharmaceuticals

Alan Munro

Merged with Xenova

Group Ltd

Chris LoweJ. McCann

Cambridge Sensors

Affinity chromatography

Chris LoweKen Jones

Acquired by Prometic

Biosciences Inc

HolometricaRoger MillingtonAbcam

Jonathan MilnerDavid Cleevely

AdproTechPeter Lachmann

Biotica TechnologyPeter Leadlay Jim StauntonKudos

PharmaceuticalsStephen Jackson

Hexagen. Mark Bodmer

Mark Bodmer Lorantis

Acquired by Incyte

Sense Proteomics

Jonathan Blackburn

De NovoPhilip Dean David Bailey

Paradigm Therapeutics

Mark Carlton

Metris Therapeutics

Stephen SmithSteve Charnock-Jones

Smart Holograms

Chris Lowe

Purely Proteins

Chris Lowe David Bailey

DaniolabsPaul Goldsmith Akubio

MCDavid Klenerman, Tony Minson

Astex Technology

Tom Blundell Chris AbellHarren Jhoti

SolexaShankar BalasubramanianDavid Klenerman

Vernalis

Arakis

Andy RichardsCyclacel

Microscience

Ark Therapeutics

VecturaReNeuron

Biovex

Genzyme (UK) - 1985

Chris EvansChris Lowe

Merlin BiosciencesChris

Evans

Figure 3 – The biotech start-ups from Cambridge University and other individuals

Cambridge Theranostics

Jonathan MilnerDavid Cleevely

Ivan Petyaev

Entrepreneurial Overlap – “Joined Up Thinking and Actions” – Coherence and Common Purpose

EDUCATION&

RESEARCHincluding Universities

INDUSTRY&

BUSINESS

GOVERNMENTNational & Local

Building an Enterprise Society. Power of Entrepreneurship, Innovation and Networking-

Building “bottom up”“bottom up”

Building communities of enterprise,social inclusion and

common purpose

Sub-regional development

Regional economic development

National economy

The Cambridge Phenomenon – Fulfilling the Potential – 2004 Report to Government

“Greater Cambridge is one of the most dynamic sub-regions within the UK Economy”

GDP growth 6.5% p.a. ( UK 3.4%, USA 3.8%) Employment Growth 5,000 p.a.(160,000 1971 – 2001) 3,500 High Technology businesses 50,000 High Technology jobs 80% Job Growth ( UK 16 % ) 360,000 jobs in total UK Exchequer tax take £5.5 billion Export value - £2.8 billion Gross Value Added - £12.2 billion ( 2001 )

The Greater Cambridge Partnership - GCP Super Sub-region

One of Europe’s Innovation Capitals

• University of Cambridge ranked No. 1 in Europe, No.4 in the world• International hub linked to finance and global markets• £12 billion+ economy; 750,000 people• 1,500+ hi-tech companies; 250 biotech companies• 30% of workforce employed in knowledge-based industries• European Union certified centre of excellence for innovation and hi-tech business• Where Entrepreneurship has driven positive development

Cambridge

source: Cambridge 2020 report - 1998

The East of England RegionMap of Silicon Valley inset

Sources of Competitive Advantagefor Greater Cambridge – EntrepreneurialEntrepreneurial

LeadershipLeadership – brought Positive Innovative Change Capacity for innovation Diverse science base and research infrastructure Capability to diffuse knowledge and experience through

collective learning and networking systems Leading to a functioning knowledge-based cluster Entrepreneurial business community – enthusiastic to

participate in local, regional, national and international programmes of innovation, change and new business creation

Centre for Entrepreneurial Learning in Judge Business School

Open Culture – Community Spirit +++++ An Enterprise Society of Common Purpose and Social

Inclusion – Entrepreneurial Integration and LeadershipEntrepreneurial Integration and Leadership

But for the Future – Beware Arrogance – “Today’s Peacock is Tomorrow’s Feather Duster”

In In Pursuit of Excellence ! of Excellence !

“Excellence can be achieved, if we:Care more than others think is wise,Risk more than others think is safe,

Dream more than others think is practical,Expect more than others think is possible.”

Deborah Johnson-Ross

Maybe Entrepreneurs think this way?....If Academics and Public Policy makers do too….we have a powerful

combination….which impacts upon Society and the whole Economy.

Thank you for your attention….

More on my website –

www.alanbarrell.com

E-mail – [email protected]