regenerativna medicina- priložnost za podjetja? miomir knežević nacionalni inštitut za biologijo...
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Regenerativna medicina-priložnost za podjetja?
Miomir KneževićNacionalni inštitut za biologijo
Uporabljeni material:
• Stem cells and the innovation process
– Dr Paul Martin– Institute for the Study of
Genetics, Biorisks and Society (IGBiS)
• University of Nottingham, UK
Global commercialisation of UK stem cell research
Nicola Perrin: [email protected]
Ian Bunker: [email protected]
The Role of Technology Foresight in Anticipating Global Technology Trend, Terutaka KUWAHARA, NISTEP
0
5
10
15
2005 2010 2015 2020 2025 2030
Time of technological realization
Gap
(ye
ars)
Information/communications
Electronics
Life science
Health/medicine/welfare
Agriculture, etc,
Frontier
Energy/resources
Environment
Nanotechnology/materials
Manufacturing
Industrial infrastructure
Social infrastructure
Social technology
* Nuclear fusion energy area isexcluded.
Innovative nuclear power systems
New informationandcommunicationsprinciples
Basictechnology forrobotic andmanned spaceactivity
Regenerative medical science
NEMStechnology
Environmental and ecological biology
Clean-use technologyfor fossil resources
Nano devices and sensors
Zakasnitveni čas od tehnološke realizacije do uporabe
2005- 2015 2015-2025
2015年までに積極的に進めるべき融合・連携関係
2016-2025年までに積極的に進めるべき融合・連携関係
(注1)各分野で融合・連携を進めるべき当該分野以外の分野を3つまで回答。(注2)各分野で融合・連携を進めるべきと3割以上が回答した分野に向けて→を表示し、 双方が該当する場合は← →で表示。(注3)赤太線は5割以上が、融合・連携が必要であると回答した領域間である。
情報・通信
ライフサイエンス
エレクトロニクス
フロンティア
エネルギー資源
保健・医療・福祉農林水産・食品
環境
ナノテク材料
製造
産業基盤
社会基盤
社会技術
情報・通信
ライフサイエンス
エレクトロニクス
フロンティア
エネルギー資源保健・医療・福祉
農林水産・食品
ナノテク材料
製造
産業基盤
社会基盤
社会技術
環境
2015年までに積極的に進めるべき融合・連携関係
2016-2025年までに積極的に進めるべき融合・連携関係
(注1)各分野で融合・連携を進めるべき当該分野以外の分野を3つまで回答。(注2)各分野で融合・連携を進めるべきと3割以上が回答した分野に向けて→を表示し、 双方が該当する場合は← →で表示。(注3)赤太線は5割以上が、融合・連携が必要であると回答した領域間である。
情報・通信
ライフサイエンス
エレクトロニクス
フロンティア
エネルギー資源
保健・医療・福祉農林水産・食品
環境
ナノテク材料
製造
産業基盤
社会基盤
社会技術
情報・通信
ライフサイエンス
エレクトロニクス
フロンティア
エネルギー資源保健・医療・福祉
農林水産・食品
ナノテク材料
製造
産業基盤
社会基盤
社会技術
環境
Information and communications
Electronics
Life sciencesLife sciences
Information and communications
Electronics
Space, marine and earth science Space, marine
and earth science
Environment
Environment
Energy and resources
Energy and resources
Manufacturing
Manufacturing
Nanotechnology and material
Agriculture, forestry, fisheries and food
Agriculture, forestry, fisheries and food
Social infrastructure
Social infrastructure
Industrial infrastructure
Industrial infrastructure
Health, medical care and welfare
Health, medical care and welfare
Science and technology for society
Science and technology for society
*1 Respondents chose at most three fields to cooperate. *2 Black arrow indicates that 30% to 50% of respondents. *3 Red arrow indicates that more than 50% of respondents.
Nanotechnology and material
Nanotechnology and material
Multidisciplinarno okolje – Vede o življenju postajajo center
Basic research in drug development
Regenerative medical science
Technology for measuring biological substances
Environmental and ecological biology
Controlling higher-order biological functions
Higher-order brain functions
Brain generation and growth
Bioinfomatics
Basic research for new medical technologies
Nanobiology
Understanding and treating brain conditions
Inde
x po
veča
nja
znan
ja
Socialno-ekonomski pomen
Po 2015
Pred 2015Sprememba vpliva “Ved o življenju”
Predvideni čas realizacije tehnologij – Vede o življenju
Čas uporabe v praksi
9.0 yrs.
9.0 yrs.
10.8 yrs.
10.6 yrs.
11.4 yrs.
10.8 yrs.
11.3 yrs.
11.0 yrs.
10.6 yrs.
2005 2010 2015 2020 2025 2030 2035
Information biology
Controlling higher-order biologicalfunctions
Basic research in drug development
Technology for measuring biologicalsubstances
Environmental and ecological biology
Nanobiology
Regenerative medical science
Understanding and treating brainconditions
Basic research for new medicaltechnologies
Bioinformatics
Controlling higher-order biological functions
Technology for measuring biological substances
Understanding and treating brain conditions
Basic research for new medical technologies
Basic research in drug development
Environmental and ecological biology
Nanobiology
Regenerative medical science
Čas tehnološke realizacije
Najpomembnejše tehnologije na področju Ved o življenju “Top 10”
Topic Area Year
Effective technology to prevent cancer metastasis. Basic research for new medical technologies
2020 / 2030
Technology for immediate, complete control of allergies based on elucidation of the immunoregulatory mechanisms and environmental factors that lead to hay fever, atopic dermatitis, and other allergies.
Basic research for new medical technologies
2015 / 2027
Treatment for preventing the progression of Alzheimer's disease. Understanding and treating brain conditions
2019 / 2030
Elucidation of the etiology of manic-dpressive psychosis at the molecular level.
Understanding and treating brain conditions
2020 / -
Technology to detect a cancerous tissue of the diameter smaller than 1 mm presenting anywhere in the body.
Technology for measuring biological substances
2014 / 2023
Elucidation of the etiology of schizophrenia at the molecular level. Understanding and treating brain conditions
2022 / -
Technologies for drug development to predict bioactivities of proteins such as interactions between protein and protein, between proteins and DNA or RNA, and between proteins and synthetic compounds from their higher order structure.
Basic research in drug development
2015 / 2026
Mass production technology for fuels and bioplastics utilizing plants and microorganisms.
Environmental and ecological biology
2014 / 2024
Technology to manipulate stem cell differentiation and growth for induction of functional cells to use for therapy.
Regenerative medical science
2016 / 2029
Effective cancer prevention measures can be implemented by clarifying the relationships among multiple environmental risk factors associated with cancer.
Basic research for new medical technologies
2020 / 2030
: Nove medicinske tehnologije in zdravila: Študij možganov
: Regenerativna medicina
Regenerativna medicinaTehnološka pot
Izdelava umetnih
organov
Razvoj osnivne
tehnologije
Long-term organ cultivation and preservationtechnology for organ transplants.
Reprograming technology to create stemcells from differentiated somatic cells.
Technology to manipulate stem celldifferentiation and growth for induction offunctional cells to use for therapy.Technology to utilize animals as a bioreactorto produce organs and tissues to transplantinto humans.
Artificial retinas to give sight to the visuallyimpaired.
Artificial organs incorporating human cellsand tissue.Synthetic technology for artificial cells withfunctions such as cell membrane transport,material transfer, and energy conversion.
2025 2030 20352005 2010 2015 2020
Time (years)
Value
5 10 15 20
Training
Cell therapies
Research tools Clinical trials
Manufacturing
Drug screening
Cell banking
Growth factors
Toxicity testing
Therapeutics
Research applications
Enabling technologies
Timescale for commercial opportunities
Stopnje:
Infrastruktura:
Deležniki:
Financiranje:
????
Basic ResearchApplied Development
Clinical Therapies
Universities, Research Institutes
Biotech SMEs Pharma
Clinicians
Government / regulatory agencies
Commercial funding VC, pharma
Research Councils Charities
Manufacturing
Funding Gap
Translation of stem cell research into commercial products
Noben uspeh ni dokončen, nobena napaka ni nepopravljiva: šteje le pogum, da nadaljuješ.
Winston Churchill