REDEFINE YOUR FUTUREIncorporating innovative science into the development of personal care and nutritional products gives you exclusive access to a premier anti-aging business opportunity. By leveraging the growing anti-aging megatrend with scientifically proven ageLOC® products, Nu Skin empowers you to build and share your business with others. Experience an opportunity that’s unsurpassed in the anti-aging industry—discover the di�erence demonstrated today.

WE ARE THEFUTURE OF

Glance forward in time—see a more youthful you. Your complexion appears smoother and more radiant. Your body feels healthier and more vibrant. At Nu Skin we’re committed to helping you achieve the best version of you. With state-of-the-art skin care solutions and nutritional

supplements formulated to help you defy the aging process, you have the tools you need. And now, with our exclusive science, you can look and feel young. ageLOC products are the only internal/external product systems developed from Nu Skin’s proprietary anti-aging science that targets

the sources of aging. Skin care for the outside and supplements for the inside bring your mind and body back into balance. Working together these products create a perfect formula—giving you the key to living younger longer.

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No one wants to look or feel old. Even as we age, we all want our bodies and minds to continue feeling youthful and healthy. The key is to give the body what it needs so it can continue to do what it is designed to do—live young.

Introducing Nu Skin’s most advanced anti-aging supplement—ageLOC Y-Span. This revolutionary supplement is designed to promote your youth span—the years you can enjoy life being more active, energetic, and healthy.

ageLOC Y-Span—Live more youthful years.

LIVE MORE YOUTHFUL YEARS

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YOUTHFUL AGING The human body is a miracle. It naturally learns, evolves, and repairs itself. In fact, it is designed to live young.

We are all born with internal aging defense mechanisms designed to resist the effects of aging. But over time, external and internal influences can disrupt natural youthful activity of these mechanisms and accelerate aging effects in the body.

Exclusive ScienceAt Nu Skin, we are continually researching how gene expression affects our aging defense mechanisms. This enables us to create products that better target the sources of aging. ageLOC Y-Span promotes the expression of key groups of genes to support healthy aging defense mechanisms, which provide the body with powerful, protective anti-aging support.

Unique Ingredient BlendThe power is in ageLOC Y-Span’s innovative ingredient blend that provides nutrients not readily available even from a healthy diet. We carefully selected ingredients not only for their nutritional contribution, but also for their:1. Unique health benefits2. Ability to positively affect gene expression.

The result? An innovative formula that strengthens and supports aging defense mechanisms—helping you age youthfully.

Remarkable ResultsageLOC Y-Span promotes the body’s natural ability to fight aging by boosting our internal aging defense mechanisms.

As our most advanced anti-aging supplement ever, ageLOC Y-Span:1. Targets our innate ability to resist aging at its source. 2. Positively modulates gene expression with a unique blend of nutrients 3. Influences multiple aging defense mechanisms to provide broad-spectrum nutritional benefits.

WHAT ARE AGING DEFENSE MECHANISMS?Aging defense mechanisms are the body’s way of promoting the healthy regulation of damage and repair processes. However, as we age, changes in gene expression cause the body’s aging defense mechanisms to decline in function, performance, and ability.

ageLOC®    Y-Span maintains and supports the activity and function of the body’s aging defense mechanisms by positively modulating gene expression, helping us to live youthfully.

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What does it mean to defy your age? For those in their late teens to their 20s, it could mean preserving their youth. For those in their 30s to 40s, it might mean slowing down the aging process. Those in their 50s to 60s, this may perhaps entail good health for a longer period of time. And for those in their 70s and above, this may possibly involve more strength and a sound mind.

Defying your age is striving for a quality life. With ageLOC technology, we are no longer cornered into how generations are previously classified. Today’s senior citizens think and act differently from their counterparts times past—after retirement, they look forward to second lease in their life, may it be another career or endeavor. And the young professionals are on the lookout for other opportunities aside from their careers, while considering their health more and more.

The Human Body is a Miracle—it naturally learns, evolves, and repairs itself. We are all born with aging defense mechanisms designed to resist the effects of aging.

Unfortunately, lifestyle and environment can disrupt these defenses and accelerate aging.

AGELOC Y-SPANSupports your body’s innate aging defense mechanisms and provides systemic anti-aging benefits. It is our most advanced anti-aging supplement for adults of any age.

ageLOC Y-Span can help prolong the years you can be active, energetic and healthy—the years you can enjoy life. It’s about having “Youth Span.”

MAJOR BODY SYSTEMS PROTECTED

A unique blend of nutrients that can

positively influence gene expression & is not readily

available even from a healthy diet.

ageLOC Y-Span Ingredients

HOW DO WE LIVE MORE YOUTHFUL YEARS?

Brain and Immune Health

Heart and Metabolic Health

Bone and Joint Health

Eyes and Physical Performance

Skin Health

Antioxidant Protection

Improve Metabolism

Cellular Stress

Response

DNA Protection

Inflammatory Balance

Tissue Regeneration

ADM

ADM

ADM

ADM

ADM

ADM ADM

Aging Defense Mechanisms (ADM)D-limonene

Astaxanthin

Lycopene

CoQ10

Resveratrol

Rosemary Leaf Extract Quercetin

Alpha Lipoic Acid

Purple Corn Extract

Citrus Bioflavonoid

Fish Oil

Vitamin D3

D-Limonene

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LTO ORDER PROCESS

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STEP: 1 Go to lto.nuskin.com and select Philippines as your home market.

STEP:2 Click

AGELOC Y-SPANLIMITED TIME OFFERTHE POWER TO DEFY YOUR AGEageLOC Y-Span, a revolutionary supplement that helps revitalize your aging defense mechanisms. Nu Skin’s most advanced anti-aging supplement ever, ageLOC Y-Span is designed to promote your youthful years, so you can enjoy life being more active, energetic, and healthy.

ORDER NOW

ORDER NOWSTEP:3 Enter the information needed then click CONTINUE

STEP:4 Verify the information and proceed to click CONTINUE.

PH0000000

STEP:5 Select the quantity you want to purchase and click CONTINUE

AGELOC Y-SPAN

PhP 56,000 1000

Live more youthful years with ageLOC Y-Span. This product promotes the optimal expression of key groups of genes and delivers enhanced nutritional benefits. It supports healthy aging defense mechanisms and provides the body with powerful, protective anti-aging support to help one age youthfully.*

This LTO Pack is composed of 10 bottles of ageLOC Y-Span.* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

STEP:6 a.)Verify the quantity; b.) select your payment method and fill the information; c.) click the checkbox of the agreement statement to confirm; d.) Submit your order

once all the information are correct.

a.

b.

c.

d.

PhP 56,000 PhP 56,000

PhP 56,000

PhP 56,000

1000ageLOC Y-Span

1000

STEP:7 Remember to keep the web reference number in case you want to check the status of your order.

PhP 56,000ageLOC Y-Span PhP 56,000

PhP 56,000

PhP 56,000

10001

1000

ORDERING PROCESS

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

www.nuskin.com.ph

POSITIONING STATEMENTIntroducing ageLOC Y-Span, a revolutionary supplement that helps revitalize your aging defense mechanisms. Nu Skin’s most advanced anti-aging supplement ever, ageLOC Y-Span is designed to promote your youth span—the years you can enjoy life being more active, energetic, and healthy.*

ageLOC Y-Span—Live more youthful years.

CONCEPT The human body is a miracle. It naturally learns, evolves, and repairs itself. In fact, it is designed to live young.

We are all born with internal aging defense mechanisms designed to resist the effects of aging. But over time, external and internal influences can disrupt natural youthful activity of these aging defense mechanisms and accelerate aging effects in the body.

No one wants to look or feel old. Even as we age, we all want our bodies and minds to continue feeling youthful and healthy. The key is to give the body what it needs so it can continue to do what it is designed to do—live young.

At Nu Skin, we have a unique understanding of how gene expression affects our aging defense mechanisms. This enables us to create products that target the sources of aging. ageLOC Y-Span promotes the optimal expression of key groups of genes and delivers enhanced nutritional benefits. It supports healthy aging defense mechanisms and provides the body with powerful, protective anti-aging support to help us age youthfully.*

The power is in ageLOC Y-Span’s innovative ingredient blend that provides nutrients not readily available even from a healthy diet. We carefully selected ingredients for their unique health benefits and ability to positively impact gene expression. The result: an innovative formula that strengthens and supports our aging defense mechanisms. ageLOC Y-Span gives you the power to defy your age.*

AGING INSIGHTS • The aging population is increasing and younger

people want to avoid early signs of aging.1• Seniors are not accepting traditional “elderly”

stereotypes. They want to retain—or regain—their youth. They may have aged in years, but their attitudes are as young as ever.2

• Today’s grandparents don’t feel like they look or act like the grandparents of a generation ago.2

• Many seniors are delaying retirement to help them stay active and maintain their current lifestyles.3

• 25–35 year olds take a very hands-on approach to their health care, often turning to the Internet for more information on their health and supplement options.4

• Many parents are having children later in life and worry about maintaining their health and energy levels.5

1 “ Aging Population and Advanced Product Offerings Drive the Global Anti-Aging Products Market,” Prweb, 2014

2 “Don’t Call Me Grandma,” Mintel, May 20113 “Age of Adventure,” Mintel, October 20104 “ Spotlight On Gen Y—Findings from Healthy World Report,” Televox,

20135 “The Ideal Age to Have a Baby,” Psychology Today, June 2012

N U S K I N ® P R O D U C T I N F O R M A T I O N P A G E

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WHAT MAKES THIS PRODUCT UNIQUE?• Our most advanced anti-aging supplement ever,

ageLOC Y-Span targets our innate ability to resist aging at its source.*

• Contains a unique blend of nutrients that is not readily available from even a healthy diet.*

• Built on more than three decades of scientific knowledge.*

• Created with our scientific understanding of the expression of key groups of genes related to the aging process, as well as antioxidant and nutritional science.*

• Positively modulates gene expression to support healthy aging defense mechanisms.*

• Influences multiple aging defense mechanisms to provide broad-spectrum nutritional benefits.*

• It is SCS certified. Measure the antioxidant difference ageLOC Y-Span is making in your body.*

PRIMARY BENEFITS 1. Our most advanced anti-aging supplement ever,

ageLOC Y-Span targets our innate ability to resist aging at its source.*

2. ageLOC Y-Span positively modulates gene expression with a unique blend of nutrients that are not readily available from even a healthy diet.*

3. ageLOC Y-Span influences multiple aging defense

mechanisms to provide broad-spectrum nutritional benefits and to promote healthy:*

• Systemic balance• Cellular response • DNA integrity• Systemic cytokine responses• Antioxidant protection• Brain • Eyes• Heart • Skin• Immune function• Bones• Joints• Lipid metabolism• Physical performance

WHO SHOULD USE THIS PRODUCT?Men and women 18 and over who want to maintain their youth and live a healthier, more youthful life.

COMPLEMENTARY PRODUCTS ageLOC® R2—helps you renew and recharge with two powerful formulas. ageLOC R2 Night optimizes each cell’s natural purification process, and ageLOC R2 Day optimizes cellular energy production.*

Pharmanex Solutions—provide targeted benefits to complement the anti-aging benefits of ageLOC Y-Span.* Please read all information and warning labels when combining supplements and consult your physician if you have any questions or concerns about your supplementation regimen.

g3—this gâc superfruit juice is validated by science to support cellular rejuvenation and immune health. Deliciously sweet, yet slightly tart, g3 provides powerful antioxidant protection while supporting healthy immune function.*

FREQUENTLY ASKED QUESTIONSWhat are aging defense mechanisms?Aging defense mechanisms are the body’s way of fighting off and maintaining resistance to aging aggressors by promoting the healthy regulation of damage and repair processes. As we age, changes in gene expression cause the body’s aging defense mechanisms to decline in function, performance, and ability. ageLOC Y-Span maintains and supports the activity by positively modulating gene expression, helping us to live youthfully.*

What is contained in the ageLOC Y-Span ingredient blend that is hard to find in a regular diet?Our ingredient screening led to the identification of several natural ingredients not common in foods consumed on a regular basis, even among individuals who strive to eat a healthy diet. Ingredients that met our unique criteria are purple corn extract,4,7 alpha lipoic acid,1,4,6,7 D-limonene,*7 CoQ10,1 citrus bioflavonoids and resveratrol. Other ageLOC Y-Span ingredients, although found in healthy diets, have been included in amounts consumers have a difficult time obtaining from their diet alone. These include astaxanthin,1,2,3 rosemary extract,7 EPA, DHA, vitamin D,7 and quercetin.

*Some markets use Orange Oil as a source of D-Limonene1-7 This ingredient not found in: 1 South & Central America; 2 Thailand; 3 Pacific Region; 4 EMEA; 5 Japan; 6 Korea; 7 Greater China

What is different about the ageLOC Y-Span capsules?ageLOC Y-Span takes advantage of a unique technology, called Licap®, that allows delivery of both liquids and solids together in a hard shell capsule. Delivering ageLOC Y-Span through this technology improves the bioavailability of fat-soluble ingredients, which helps ensure the delivery of anti-aging benefits.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

www.nuskin.com.ph

www.nuskin.com.ph

How is ageLOC Y-Span di�erent from LifePak?ageLOC Y-Span and LifePak were designed in di�erent ways, with di�erent science. We designed LifePak with the best nutritional and antioxidant science. We formulated ageLOC Y-Span using all three anti-aging sciences: our proprietary gene expression science combined with key antioxidant and nutritional elements for the most advanced anti-aging product possible.*

Can I take ageLOC Y-Span with ageLOC R2?Yes, you can take ageLOC Y-Span and ageLOC R2 together. Gene expression science guided the development of both products, however, we assessed their ingredient blends for distinct benefits. We formulated ageLOC R2 with benefits targeting cellular energy and cellular purification; whereas we formulated ageLOC Y-Span to support aging defense mechanisms, which guard against cellular response disruption, strengthen the body’s ability to protect and repair DNA, and provide more broad-spectrum health benefits.*

Can I take ageLOC Y-Span with other Pharmanex products? Yes, ageLOC Y-Span’s gene expression science and ability to remind our bodies how to be young complement our many other supplements. ageLOC Y-Span targets the sources of aging by influencing gene expression that impacts your aging defense mechanisms. It does this with a unique ingredient blend not easily found even in a healthy diet. These unique ingredients and their ability to positively modulate gene expression make ageLOC Y-Span an excellent core product and a powerful companion to your daily supplement regimen. Please consult your physician if you have any questions about your supplementation regimen.*

ageLOC Y-Span also contains the impressive aging defense properties provided by omega-3 fatty acids from fish oil. If you take a fat-binding product, such as DuoLean or FibreNet, it is important to take ageLOC Y-Span two hours before or after taking the fat-binding product.*

Will ageLOC Y-Span increase my skin carotenoid score? Yes, in our ingredient selection process to identify natural substances that target aging defense mechanisms, we also identified a few ingredients that will positively impact your antioxidant status.*

Has Nu Skin conducted studies on ageLOC Y-Span?There are several ageLOC Y-Span studies completed or ongoing.

DIRECTIONS FOR USETake two capsules twice daily with morning and evening meals.

KEY SCIENTIFIC STUDIES Studies to Support Ingredients Present in All Global Formulas1. Garg, A., S. Garg, L. J. Zaneveld and A. K. Singla

(2001). “Chemistry and pharmacology of the Citrus bioflavonoid hesperidin.” Phytother Res 15(8): 655-669.

2. Schmidt, S., F. Stahl, K. O. Mutz, T. Scheper, A. Hahn and J. P. Schuchardt (2012). “Di�erent gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial.” Lipids Health Dis 11: 105.

3. Bouwens, M., O. van de Rest, N. Dellschaft, M. G. Bromhaar, L. C. de Groot, J. M. Geleijnse, M. Muller and L. A. Afman (2009). “Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.” Am J Clin Nutr 90(2): 415-424.

4. Morrow, D. M., P. E. Fitzsimmons, M. Chopra and H. McGlynn (2001). “Dietary supplementation with the anti-tumour promoter quercetin: its e�ects on matrix metalloproteinase gene regulation.” Mutat Res 480-481: 269-276.

5. Devaraj, S., S. Mathur, A. Basu, H. H. Aung, V. T. Vasu, S. Meyers and I. Jialal (2008). “A dose-response study on the e�ects of purified lycopene supplementation on biomarkers of oxidative stress.” J Am Coll Nutr 27(2): 267-273.

Studies to Support Ingredients Present in All Global Formulas Except Greater China1. Yoon, W. J., N. H. Lee and C. G. Hyun (2010).

“Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, and pro-inflammatory cytokines in RAW 264.7 macrophages.” J Oleo Sci 59(8): 415-421.

2. Lean, M. Punab, A. J. Silman, D. Vanderschueren, F. C. Wu and E. s. group (2009). “Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men.” J Neurol Neurosurg Psychiatry 80(7): 722-729.

3. Zhu, H., D. Guo, K. Li, J. Pedersen-White, I. S. Stallmann-Jorgensen, Y. Huang, S. Parikh, K. Liu and Y. Dong (2012). “Increased telomerase activity and vitamin D supplementation in overweight African Americans.” Int J Obes (Lond) 36(6): 805-809.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

4. Pengelly, A., J. Snow, S. Y. Mills, A. Scholey, K. Wesnes and L. R. Butler (2012). “Short-term study on the e�ects of rosemary on cognitive function in an elderly population.” J Med Food 15(1): 10-17.

Studies to Support Ingredients Present in Many of the Global Formulas1. Villalba, I. Tunez, F. Perez-Jimenez and J. Lopez-

Miranda (2013). “Postprandial antioxidant gene expression is modified by Mediterranean diet supplemented with coenzyme Q(10) in elderly men and women.” Age (Dordr) 35(1): 159-170.

2. Schrauwen, E. C. Mariman and E. E. Blaak (2013). “The e�ects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men.” Int J Obes (Lond).

3.Li, J., M. K. Kang, J. K. Kim, J. L. Kim, S. W. Kang, S. S. Lim and Y. H. Kang (2012). “Purple corn anthocyanins retard diabetes-associated glomerulosclerosis in mesangial cells and db/db mice.” Eur J Nutr 51(8): 961-973.

4.Tsuda, T., F. Horio, K. Uchida, H. Aoki and T. Osawa (2003). “Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice.” J Nutr 133(7): 2125-2130.

5.Djordjevic, B., I. Baralic, J. Kotur-Stevuljevic, A. Stefanovic, J. Ivanisevic, N. Radivojevic, M. Andjelkovic and N. Dikic (2012). “E�ect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players.” J Sports Med Phys Fitness 52(4): 382-392.

6. K. Lee and Y. M. Kim (2003). “Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.” Mol Cells 16(1): 97-105.

7. Stoll, S., H. Hartmann, S. A. Cohen and W. E. Muller (1993). “The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits.” Pharmacol Biochem Behav 46(4): 799-805.

8. Liu, J. (2008). “The e�ects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.” Neurochem Res 33(1): 194-203.

9. Errero-Barbudo, C., B. Soldevilla, B. Perez-Sacristan, I. Blanco-Navarro, M. Herrera, F. Granado-Lorencio

and G. Dominguez (2013). “Modulation of DNA-Induced Damage and Repair Capacity in Humans after Dietary Intervention with Lutein-Enriched Fermented Milk.” PLoS One 8(9): e74135.

SUPPLEMENT FACTSServing Size 1 Capsule Servings Per Container 120Amount Per Serving % RENIVitamin D3 (as cholecalciferol) 50 IU 25%

Marine Lipid concentrate 527.5 mg *Omega 3 Fatty Acids: EPA 150 mg * DHA 100 mg *

50 mg *Purple corn (Zea mays L.) cob extract 33.3 mg *Alpha Lipoic Acid 25 mg *Quercetin (from Dimorphandra mollis fruit extract) 18.75 mg *D-Limonene 12.5 mg *Rosemary ( ) leaf extract 9.38 mg *Resveratrol (from Polygonum cuspidatum root extract) 7.5 mg *Coenzyme Q10 7.25 mg *Lycopene 1.25 mg *Astaxanthin (from Haematococcus pluvialis algae extract) 0.25 mg *

* RENI Value (DV) not established.RENI Value based on adults age 19-50

Other Ingredients: Capsule (Gelatin, Water).

WARNINGSKeep out of reach of children. If you are pregnant, lactating, or taking a prescription medication, consult a physician prior to using this product. Do not use if safety seal is broken or missing. Contains fish (anchovies, sardines, mackerel) and soy.

©2015 • Nu Skin® Enterprises Philippines, LLC Product Information Page • www.nuskin.com.ph

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