rech arge drug indication / specialty … indication / specialty commissioned by rech arge y/n...

Drug Indication / Specialty Commissioned by Recharge Y/N Comments Guidance

Key

Abacavir HIV infection NHS England Y

Abacavir & Lamivudine HIV infection NHS England Y

Abacavir/Lamivudine/Zidovudine HIV infection NHS England Y

Abatacept Juvenile arthritis NHS England Y

Abatacept

Paediatric indications where

adult TA available NHS England Y

Abatacept Rheumatoid arthritis in adults CCG Y TA195, TA230

Abiraterone Cancer services NHS England and CDF Y TA259

Acetylcysteine Respiratory medicine NHS England Y

Acitretin Psoriasis CCG Y

Adalimumab Dermatology in adults CCG Y TA146, TA199

Adalimumab Gastroenterology in adults CCG Y TA187

Adalimumab Hidradenitis Suppurativa NHS England - requires IFR Y

Adalimumab Juvenile arthritis NHS England Y

Adalimumab



Adalimumab Rheumatology in adults CCG Y TA130, TA143, TA199, TA280

Adalimumab Uveitis NHS England - requires IFR Y

Adcortyl in Orabase ENT - unlicensed CCG Y

Adefovir Dipivoxil Hepatitis B NHS England - requires IFR Y CG165

Afatinib Cancer services NHS England Y

Approved in line with NICE

guidance

Aflibercept Cancer services CDF Y

Aflibercept Ophthalmology CCG N Charge within contract

Agalsidase Alfa Metabolic disorders NHS England Y

Agalsidase Beta Metabolic disorders NHS England - non-formulary Y

Aldesleukin Cancer services NHS England Y

Alemtuzumab Cancer services NHS England Y

Alemtuzumab Multiple sclerosis NHS England Y TA132

Alemtuzumab

Pre-transplant

immunosuppression NHS England - non-formulary

Alteplase(Actilyse Cathflo) Inj Antithrombotic NHS England

Alirocumab Hypercholesterolaemia Y TA393

Alglucosidase Alfa Metabolic disorders NHS England Y

On Red list and commissioned by NHS England

Non-formulary within HEY - commissioned by NHS England

On Red list and commissioned by CCG or Public Health

Commissioned by NHS England, currently Amber - plan for repatriation

Alitretinoin Severe chronic hand eczema CCG Y TA177

Ambrisentan Pulmonary Arterial NHS England Y

Amifampridine

Lambert-Eaton myasthenic

syndrome NHS England - requires IFR

Amphoteracin eye drops Ophthalmology CCG Y

recharge if more 28/7 in

o/p

Amphotericin liposomal Intravenous antifungal NHs England Y

Amsacrine Cancer services NHS England Y

Anagrelide Hydrochloride Platelet disorders CCG Y

Anakinra Paediatric indications NHS England - requires IFR Y

Anakinra Rheumatology adult CCG - requires IFR Y

Anidulafungin Antifungal drugs NHS England Y

Antilymphocyte globulin

Aplastic anaemia / organ

transplant NHS England Y

Antithymocyte Immunoglobulin

Aplastic anaemia / organ

transplant NHS England - non-formulary

Apraclonidine eye drops Peri-operative use CCG N

Apremilast Dermatology in adults CCG N

Review when NICE final

guidance

Apremilast Rheumatology in adults CCG N

Review when NICE final

guidance

Aprepitant

Chemotherapy associated

nausea and vomiting NHS England Y supportive therapy

Argatroban Injection

Arsenic

Proctitis (acetarsol unlicensed

list) CCG Y

Artesunate HIV infection NHS England y

Artemether with lumefantrine Treatment of malaria CCG N

Asenapine Treatment of mania CCG

Atavaquone pneumocystis carinii CCG Y


o/p

Atazanavir HIV infection NHS England Y

Atazanavir/Cobicistat HIV infection NHS Engalnd y

Axitinib Cancer services CDF Y

Azacitidine Cancer services NHS England Y TA218

Azathioprine Transplant immunosuppression

NHS England - currently Amber plan to

repatriate Y

Aztreonam infusion Cystic fibrosis NHS England Y

Aztreonam Lysine Cystic fibrosis NHS England listed as suitable for shared care Y NHS England AD1/PS/a

Bacillus Calmette-Guerin (B.C.G.) Respiratory Medicine CCG N

Baricitinib Rheumatoid arthritis in adults NHS England y

Belimumab SLE NHS England - requires IFR YBendamustine Cancer services NHS England and CDF Y TA216Benzylpenicillin eye drops Eye infection - unlicensed CCG Y recharge if more 28/7 in

Beractant Pulmonary surfactant NHS England - non-formularyBetaine Anhydrous Homocystinuria NHS England Y

Bevacizumab Cancer services CDF Y

Bevacizumab Neurofibromatosis NHS England Y

Bevacizumab Ophthalmology CCG Y

Bexarotene Cancer services NHS England Y

Bleomycin Cancer services NHS England Y

Boceprevir Hepatitis C NHS England Y TA253

Bortezomib Cancer services NHS England and CDF Y TA129, TA228, TA311

Bosentan Digital ulcers NHS England - requires IFR Y

Bosentan Pulmonary Arterial NHS England Y NHS England A11/PS/b

Bosutinib Cancer services CDF - non-formulary N

Botulinum Toxin Type A Chronic migraine CCG Y

Botulinum Toxin Type A Focal spasticity in adults CCG Y

Botulinum Toxin Type A Focal spasticity in children NHS England Y

Botulinum Toxin Type A Hyperhydrosis CCG Y

Botulinum Toxin Type A

Intravesical use in spinal cord

injury NHS England - requires IFR for new patients Y

Botulinum Toxin Type A Urology indications CCG Y

Brentuximab Cancer services NHS England Y

Brivacetam/Briviact Tablets/Solution

and Injection

Adjunctive therapy in the

treatment of partial-onset

seizures CCG

Brodalumab Dermatology CCG Y

Bromfenac eye drops Peri-operative use CCG N

Busulfan Cancer services NHS England Y

C1-Esterase Inhibitor

Herditary angioedema - acute

treatment NHS England Y NHS England B09/P/b

Cabazitaxel Cancer services CDF Y

Cabozantinib Cancer services CDF - non-formulary Y

Calcitonin (salmon) Endocrinology indications CCG N

Calcitonin (salmon) Hypercalcaemia of malignancy NHS England N supportive therapy

Calcium folinate

Supportive treatments for

chemotherapy CCG N

Calcium folinate


chemotherapy NHS England N supportive therapy

Cantharone and Cantherone Plus Removal of Warts

Capecitabine Cancer services NHS England Y

Caphosol Cancer services NHS England N supportive therapy

Capreomycin Infectious diseases/TB NHS England y

Carboplatin Cancer services NHS England y

Carfilzomib Cancer services NHS England y NICE Guidance

Carglumic Acid Metabolic disorders NHS England - non-formulary

NHS England Service Spec - highly

specialised criteria only

Carmustine Cancer services NHS England Y

Carnitine Metabolic disorders NHS England Y

NHS England Service Spec - highly

specialised criteria only

Caspofungin Intravenous antifungal NHS England Y

Cefotaxime infusion Cystic fibrosis NHS England - requires IFR Y

Ceftazidime infusion Bronchiectasis CCG - requires IFR Y

Ceftazidime-Avibactam Infusion

(Zavicefta) Antibiotic NHS England

Ceftazidime infusion Cystic fibrosis NHS England - requires IFR Y

Ceftolazone/Tazobactam

Certolizumab Pegol Paediatric indication NHS England - requires IFR Y

Certolizumab Pegol Psoriatic arthritis CCG Y

Certolizumab Pegol Rheumatoid arthritis in adults CCG Y

Cetuximab Cancer services NHS England and CDF Y TA145, TA176

Chemotherapy

Cancer services - not specifically

listed NHS England and CDF Y

Chlorambucil Cancer services NHS England Y

Chlorhexidine eye drops Eye infection - unlicensed CCG Y


o/p

Chlortetracycline eye ointment Eye infection - unlicensed CCG Y


o/p

Chorionic Gonadotrophin Fertility services CCG N IVF

Ciclosporin Transplant immunosuppression


repatriate Y

Cidofovir Cytomegalovirus NHS England Y

Cinacalcet

Hyperparathyroidism - dialysis

patients only


repatriate Y

Cisplatin Cancer services NHS England Y

Cladribine Relapsing -remitting MS NHS England NICE TA493

Cladribine Cancer services NHS England Y

Clofarabine Cancer services CDF Y

Clomethiazole Alcohol dependence CCG / Public health ? N

Clomifene Citrate Fertility services CCG Y re-charge if NOT IVF

Clotrimazole eye drops Eye infection - unlicensed CCG N

Clozapine Mental health CCG

Co-careldopa intestinal gel Parkinson's disease NHS England Y

Colestilan Renal dialysis patients NHS England - non-formulary Y

Colistimethate sodium Bronchiectasis CCG Y

Colistimethate sodium Cystic fibrosis


repatriate Y TA276, NHSE AD1/PS/a

Conestat alfa

Hereditary angiodema - acute

treatment NHS England - non -formulary Y

Corticotropin Releasing Hormone Endocrinology CCG N

Crizotinib Cancer services CDF Y

Cyclophosphamide Cancer services NHS England Y

Cyclophosphamide Immunosuppression CCG Y

Cycloserine Infectious diseases/TB NHS England Y

Cytarabine Cancer services NHS England Y

Dabrafenib Cancer services CDF - not on HEY formulary Y

Dabrafenib / Trimetinib Cancer services NHS England Y

Dacarbazine Cancer services NHS England Y

Daclatasvir Hepatitis C NHS England Y

Daclizumab/Zinbryta 150mg Inj Relapsing -remitting MS NHS England

Dactinomycin Cancer services NHS England Y

Dapsone As per licence CCG Y

Daranuvir/Cobicistat HIV infection NHS England y

Darbepoetin Cancer services NHS England Y Supportive therapy

Darbepoetin Chronic renal failure not dialysis CCG Y

NHS England from April

2016

Darbepoetin Dialysis-induced anaemia NHS England Y

Darunavir HIV infection NHS England Y

Dasatinib Cancer services CDF Y

Daunorubicin Cancer services NHS England Y

Deferasirox Iron overload NHS England Y

Deferiprone Iron overload NHS England Y

Degarelix Cancer Services NHS England Y

Denosumab (XGEVA) Cancer services NHS England Y Supportive therapy

Denosumab for osteoporosis is

shared care

Desferrioxamine Mesilate Iron overload NHS England Y

Desmopressin injection Diagnostic / haemophillia CCG N

Descovy(Emtricitabine/Tenofovir

Alafenamide HIV infection

Dexmetetomidine Sedation in Critical care setting

Dexamthesaone intravitreal Macular oedema CCG Y

Dexrazoxane anthracycline extravasation NHS England - non-formulary Y

3,4 Diaminopyridine

Lambert-Eaton myasthenic

syndrome NHS England N

Diamorphine Nasal Spray Acute pain in Paeds(Emergency)

Diazoxide

Chronic hypoglycaemia -

unlicensed CCG Y

Diclofenac eye drops Peri-operative use CCG N

Didanosine HIV infection NHS England Y

Diloxanide Amoebiasis

CCG not on HEY formulary, requires Chair's

approval N

Dimethyl fumarate Mulitple sclerosis NHS England Y TA320

Dimethyl fumarate Psoriasis CCG y TA475

Disodium folinate


chemotherapy CCG N

Disodium folinate


chemotherapy NHS England N

Disofrol Chronic cough - unlicensed CCG Y

Disulfiram Alcohol dependence Public Health Y

Docetaxel Cancer services NHS England Y

Dolutegravir HIV infection NHS England Y

Dolutegravir / Abacavir/Lamivudine HIV infection NHS England Y

Dornase alfa Cystic fibrosis


repatriate Y

Doxorubicin Hydrochloride Cancer services NHS England Y

Doxorubicin Hydrochloride Cancer services NHS England Y

Doxorubicin pegylated liposomal Cancer services NHS England and CDF Y TA91

Dronedarone Arrhythmia CCG Y

Droperidol Surgery CCG

Dupilumab Severe Atopic dermatitis NHS England Y

Eculizumab

Atypical haemolytic uraemic

syndrome NHS England Y

Requires IFR if not in line

with NICE

Eculizumab

Paroxysmal nocturnal

haemoglobinuria NHS England- non-formulary Y

NHSE E03/PS(HSS)/a and NSCT

Service Spec

Efavirenz HIV infection NHS England Y

Eltrombopag platelet disorders CCG Y

Elviregravir/Cobicistat HIV Infection NHS England y

Elvitegravir with Cobicistat,

Emtricitabine and Tenofovir (Stribild) HIV infection NHS England Y NHSE B06/PS/a

Emtricitabine/Tenofovir/Alafenamide HIV infection NHS England y

Emtricitabine HIV infection NHS England - requires IFR Y

Emtricitabine & Tenofovir Disoproxil

(Truvada) HIV infection NHS England Y

Emtricitabine with efavirenz and

tenofovir (Atripla) HIV infection NHS England Y

Emtricitabine with rilpivirinr and

tenofovir (Eviplera) HIV infection NHS England Y

Enfuvirtide HIV infection NHS England y

Entecavir Hepatitis B NHS England y TA153

Enzalutamide Cancer services NHS England y TA316

Epclusa (Sofosbuvir/Velpatavir) Chronic Hepatitus C NHS England

Epirubicin Hydrochloride Cancer services NHS England Y

Epoetin Chronic renal failure not dialysis CCG Y

Epoetin Dialysis-induced anaemia NHS England y CG 114

EpoprostenolSodium Pulmonary Arterial NHS England y NHSE A11/PS/b

Eptotermin

Bone morphogenetic protein -

Complex spinal surgery NHS England - requires IFR Y

Eptotermin

Bone morphogenetic protein -

unhealing fracture CCG - requires IFR Y

Eribulin Cancer services CDF y

Erlotinib Cancer services CDF y

Estramustine Phosphate Cancer services NHS England y

Etalcalcetide Injection Secondary hyperparathyroidism NHS England y

Etanercept Dermatology in adults CCG y TA103

Etanercept Juvenile arthritis NHS England y TA35

Etanercept


adult TA available NHS England y

Etanercept rheumatology in adults CCG y TA130, TA143, TA199

Ethambutol Hydrochloride TB CCG ?

Ethionamide TB CCG - requires IFR

Etoposide Cancer services NHS England Y

Etravirine HIV infection NHS England y

Everolimus Cancer CDF y

Everolimus Transplant immunosuppression NHS England - requires IFR Y

Everolimus Renal angiomyolipoma NHS England - requires IFR y

Everolimus Tubular sclerosis NHS England - requires IFR y

Evolocumab Hypercholesterolaemia CCG Y TA394

Fampridine (Immunomodulating) Multiple sclerosis NHS England - requires IFR - non-formulary Y NHS E DD4/PS/d

Ferraccru(Ferric Maltol)

Filgrastim neutropenia NHS England y

Fingolimod Multiple sclerosis NHS England y TA254 NHS E D04/P/b

Fludarabine Phosphate Cancer services NHS England Y

Flunarizine migraine CCG Y

Fluocinolone intravitreal Ophthalmology CCG Y

Fluouracil Cancer services NHS England Y

Fluticasone Furoate/Vilanterol(Relvar)

Follitropin Alfa Fertility services CCG N

Fomepizole

Ethylene glycol and methanol

poisoning CCG Y

Fosamprenavir HIV infection NHS England

Foscarnet cream

Herpes simplex resistant to

aciclovir CCG Y

Foscarnet infusion Cytomegalovirus NHS England Y

Fosfomycin (IV only) ESBL CCG Y

Pure Fructose(Hydrogen Breath Test) Fructose Intolerent Test NHS Engalnd y

Free Style Libre CCG Y

In line with NICE guidance and

commissioning paper

Galsulfase Metabolic disorders NHS England - non-formulary Y Highly specialised criteria only

Ganciclovir Cytomegalovirus NHS England Y

Ganciclovir eye drops Ophthalmology CCG Y


o/p

Gefitinib Cancer services NHS England Y TA192

Gemcitabine Cancer services NHS England Y

Glatiramer Acetate Multiple sclerosis NHS England Y TA32 NHSE DD4/P/b

Glucarpidase

Methotrexate overdose due to

medication error in secondary

care NHS England / CCG N

Glucarpidase

Methotrexate overdose

originating in primary care CCG -requires IFR Y

Glucarpidase

Methotrexate toxicity in

secondary care NHS England Y

Glycopyrronium injection Palliative care CCG Y

Golimumab Gastroenterology in adults CCG Y TA329

Golimumab Rheumatology CCG Y TA220 TA233

Gonadorelin

hypothalamic hormones

investigative use CCG N

Granisetron

Chemotherapy associated

nausea and vomiting NHS England N supportive therapy

Granulocyte-macrophage colony-

stimulating factor neutropenia NHS England - requires IFR

Guanfacine Mental Health CCG

Haem Arginate Porphyria NHS England - non-formulary Y

Treatment usually

provided by highly

specialist service

Homatropine Ophthalmology CCG N

Human arginate Hepatic porphyria NHS England - non-formulary y Highly specialised criteria only

Humulin R insulin Diabetes mellitus - unlicensed CCG Y

Hyaluronidase Peri-operative use CCG N

Hydroxycarbamide Cancer services NHS England Y

Hydroxycarbamide Polycythaemia CCG Y

Hydroxycarbamide Sickle cell disease NHS England N

Hydroxypropyl cellulose ophthalmic

strips Ophthalmology CCG - requires IFR Y

Ibandronic acid IV only Endocrinology CCG N

Ibrutinib Cancer services NHS England Y

Icatibant

Hereditary angioedema - acute

treatment NHS England Y NHSE B09/P/b

Idarubicin Hydrochloride Cancer NHS England Y

Idarucizumab Haematology CCG

Idebenone

for slowing the decline of

respiratory function, in patients

with Duchenne Muscular

Dystrophy NHS England

Ifosfamide Cancer services NHS England Y

Iloprost Pulmonary Arterial NHS England Y NHSE A11/PS/t

Iloprost Rheumatology indication CCG

Iloprost Vascular indications CCG

Imatinib Mesilate Cancer Services NHS England and CDF Y TA70, TA86, TA251

Imatinib Mesilate Graft versus host disease NHS England - requires IFR Y

Imiglucerase Metabolic disorders NHS England -non-formulary Highly specialised criteria

Indinavir HIV infection NHS England Y

Infliximab Crohn's disease in children NHS England Y TA187

Infliximab Dermatology in adults CCG Y TA134

Infliximab Gastroenterology in adults CCG Y TA 140, TA 163

Infliximab Hidradenitis Suppurativa NHS England - requires IFR Y

Infliximab Interstitial lung disease NHS England - requires IFR Y

Infliximab Paediatric indications in NHS England Y

Infliximab Renal NHS England - requires IFR Y

Infliximab Rheumatology in adults CCG Y TA130, TA143, TA199

Infliximab Sarcoidosis NHS England - requires IFR Y

Infliximab Uveitis NHS England - requires IFR Y

Interferon Alpha Hepatitis B and C NHS England Y TA75

Interferon Beta Mulitple sclerosis NHS England Y TA32 DD4/P/b

Iodine Oral Solution (Lugol's) Thyroid surgery CCG N

Ipilimumab cancer services NHS England Y

Irbutinib Cancer services NHS England Y

Irinotecan Hydrochloride cancer services NHS England Y

Iron dextran Iron deficiency anaemia CCG N

Iron isomaltoside Iron deficiency anaemia CCG N

Iron isomaltoside Iron deficiency anaemia CCG N

Iron sucrose complex Iron deficiency anaemia CCG N

Isoniazid TB CCG N

Isotretinoin Acne CCG Y

Ivacaftor CF with G551D gene mutation NHS England Y NHSE AD1/P/b

Ivermectin Parasiticidal prep CCG Y


o/p

Intravenous drugs not specifically listed in this table are considered Red, within Tariff unless recommended for non-specialist use in specific guidance.

Ixekizumab (Talz) Pre filled syringe

Ketamine Hydrochloride Chronic pain CCG - IFR only Y

Ketamine Hydrochloride Palliative care CCG Y

labinic Liquid

Prevention of Necrotizing

Enterocolitis NHS England

Lamivudine Hepatitis B NHS England Y CG165

Lamivudine HIV infection NHs England Y

Lamivudine & Zidovudine HIV infection NHS England Y

Lanthanum Renal dialysis


repatriate Y

Lapatinib Cancer services CDF Y

Laronidase Metabolic disorders NHS England - non-formulary Y Highly specialised criteria only

L-carnitine Carnitine deficiency NHS England Y Highly specialised criteria only

Lenalidomide Cancer services NHS England and CDF Y TA171

Lenograstim neutropenia NHS England Y

Levamisole Antihelmintic CCG Y


o/p

Levofloxacin Antibiotic NHS England

Linezolid Antibiotic CCG Y


o/p

Lomustine Cancer services NHS England Y

Lopinavir & Ritonavir HIV infection NHS England Y

Lumicaftor-Ivacaftor Cystic fibrosis NHS England y

Macitentan Pulmonary Arterial NHS England Y NHS England Policy: A11/PS/b

Mannitol Cystic fibrosis NHS England Y TA256

Maraviroc HIV infection NHS England Y

Mecasermin Growth failure NHS England - non-formulary

Melphalan cancer services NHS England Y

Mepolizumab/Nucala Injection

Severe refractory eoinophilic

Asthma

Mepacrine Rheumatology - unlicensed CCG Y

Mercaptamine Nephropathic cystinosis NHS England - non-formulary

Meropenem infusion Bronchiectasis CCG - requires IFR Y

Meropenem infusion Cystic fibrosis NHS England - requires iFR Y

Mesna


chemotherapy CCG N supportive therapy

Mesna


chemotherapy NHS England N

Methotrexate Cancer services NHS England Y

Methoxypsoralen PUVA CCG N

Methyl-5-aminolevulinate actinic keratosis CCG N

Methyl-5-aminolevulinate Basal cell carcinoma CCG N

Methysergide Migraine - unlicensed CCG Y

Metolazone Loop diuretic - unlicensed CCG Y

Micafungin Antifungal drugs NHS England - non-formulary

Midodrine Hydrochloride Hypotension -unlicensed CCG Y

Migalastat Metabolic disorders NHS England - non-formulary Y Highly specialised criteria

Miglustat Metabolic disorders NHS England - non-formulary Y

Mitomycin cancer services NHS England Y

Mitotane cancer services NHS England Y

Mitoxantrone cancer services NHS England Y

Modafanil Unlicensed indications CCG Y

Moxifloxacin


o/p

Mycophenolate mofetil Transplant immunosuppression


repatriate Y

Mycophenolic acid Transplant immunosuppression


repatriate Y

Nabilone Chronic pain CCG Y

Nalmefene Alcohol dependence Public health Y

Naltrexone Alcohol dependence Public Health Y

Natalizumab Multiple sclerosis NHS England Y

TA127 & NHS England Policy:

D04/P/b

Natamycin Eye Drops Ophthalmology CCG unlicensed

Nelarabine Cancer services CDF Y

Nelfinavir HIV infection NHS England Y

Nevirapine HIV infection NHS England Y

Nicardipine Hydrochloride Inj

Nilotinib Cancer services NHS England and CDF Y TA241 & TA251

Nimodipine Subarachnoid haemorrhage CCG N

Nintedanib idiopathic pulmonary fibrosis NHS England Y

Niraparib (Zejula) 100mg Capsules

Recurrent platinum-sensitive

epithelial ovarian, fallopian

tube, or primary peritoneal

cancer NHS England

status to be reviewed when NICE

TA is published

Nitisinone Metabolic disorders NHS England - non-formulary Y

Nitric oxide Pulmonary Arterial NHS England Y

Nivolumab Cancer Services NHS England Y TA490/462

Obeticholic Acid (Ocaliva) Capsules Primary biliary cholangitis

Normal Immunoglobulin (Gamma

Globulin) Immunological products NHS England Y

Obinutuzumab Chronic Lymphocytic Leukaemia y TA343

Odefsey(Rilpivirine/Emtricitabine/Ten

ofovir) HIV infection

Ocrelizumab MS NHS England Y

Ocriplasmin Vitreomacular traction CCG Y TA297

Ofatumumab Cancer services CDF YOfloxacin recharge if more 28/7 in Olaparib Ovarian, FallopianTube and TA381Olaratumab (Lartruvo) infusion Soft tissue carcinoma NHS England TA465

Omalizumab Asthma NHS England Y TA278

Omalizumab Chronic spontaneous urticaria NHS England - requires IFR Y

Oxaliplatin Cancer services NHS England Y

Paclitaxel Cancer services NHS England Y

Paclitaxel albumin bound Cancer services CDF Y

Palivizumab RSV prophylaxis NHS England Y

Palbociclib Capsules hormone receptor NHS England

Pamidronate Cancer services NHS England N supportive therapy

Pamidronate Paget's Disease CCG N

Panitumumab Cancer services CDF Y

Panobinostat Cancer services NHS England Y TA380

Papaverine Erectile dysfunction - CCG Y

Parathyroid Hormone

Specialist endocrinology

conditions NHS England - non-formulary

Parenteral nutrition

Intestinal failure;

inadequate/unsafe enteral

feeding NHS England Y As per Manual

Paricalcitol Secondary hyperparathyroidism NHS England N

Pasireotide Cushing's Disease NHS England - requires IFR Y

Pazopanib Cancer services NHS England Y

Pazopanib Cancer services NHS England and CDF Y TA215

Pegaptanib Sodium Ophthalmology CCG - requires IFR, non-formulary Y TA155

Pegfilgrastim neutropenia NHS England - requires IFR Y

Peginterferon Alpha Hepatitis B and C NHS England Y

TA75, TA96, TA106, TA200, TA 300,

CG165

Peginterferon beta-1a Multiple sclerosis NHS England - requires IFR Y

Pegvisomant

Third-line treatment for adults

with acromegaly, following a

pituitary MDT meeting NHS England Y

Approved in line with NHSE

specialist clinical commissioning

policy (16050/P),

Pemetrexed Cancer services NHS England and CDF Y TA135, TA181, TA190

Pemrolizumab Infusion

Pentosan Polysulphate Sodium Interstitial cystitis CCG Y

Pentostatin Cancer services NHS England Y

Pentoxyfilline

Immunology indications

(unlicensed) CCG Y

Pentoxyfilline

Gastroenterology indications

(unlicensed) CCG Y

Peptide receptor radionucleotide

therapy Cancer services CDF Y

Pertuzumab Cancer services CDF - non-formulary Y

Pharmalgen Immunology indications NHS England N

Phenoxybenzamine

Phaeochromocytoma -

unlicensed CCG Y

Phentolamine Erectile dysfunction - CCG Y

Phenylbutazone

Ankylosing spondylitis -

unlicensed CCG Y

Piperacillin / Tazobactam infusion Bronchiectasis CCG - requires IFR Y

Piperacillin / Tazobactam infusion Cystic fibrosis NHS England - requires IFR Y

Pirfenidone idiopathic pulmonary fibrosis NHS England Y TA282 (specialist centre only)

Pixantrone Cancer services CDF - non-formulary Y TA 306

Plenvu Bowel Screening CCG Y

Plerixafor stem cell mobilisation NHS England - non-formulary Y NHS England policy: B04/P/2

Polihexanide eye drops Ophthalmology CCG Y


o/p

Pollinex Quatro Immunology NHS England N

Pomalidomide Cancer services CDF - non-formulary Y

Ponatinib Cancer services CDF - non-formulary Y

Poractant alfa Respiratory distress syndrome NHS England Y

Posaconazole Antifungal drugs NHS England Y

Potassium ascorbate eye drops Peri-operative use CCG N

Povidone iodine eye drops Peri-operative use CCG N

Praziquantel Antihelmintic CCG Y


o/p

Primaquine Treatment of malaria CCG Y


o/p

Probenecid Hyperuricaemia - unlicensed CCG Y

Procarbazine Hydrochloride Cancer services NHS England Y

Proguanil with atavaquone Treatment of malaria CCG Y


o/p

Propamidine eye drops Ophthalmology CCG Y


o/p

Protirelin hypothalamic hormones CCG N diagnostic inhouse

Pyrazinamide TB CCG N

Pyridoxine SF liquid TB CCG N

Pyrimethamine Malaria / toxoplasmosis CCG N


o/p

Pyrimethamine TB CCG N

Quinine Treatment of malaria CCG N


o/p

Radium-223 Dichloride Cancer services CDF - non-formulary Y

Raltegravir HIV infection NHS England Y

Raltitrexed Cancer services NHS England Y

Ranibizumab Ophthalmology CCG Y TA155

Rasburicase Hyperuricaemia NHS England Y

Regorafenib Gastrointestinal stromal NHS England Y NICE TA 488 NICE TA488

Reslizumab Injection Respiratory

Ribavirin Hepatitis C NHS England Y TA75, TA106, TA200

Rifabutin TB CCG N

Rifampicin TB CCG N

Rifampicin Combined Preparations TB CCG N

Rifaximin Immunology CCG Y

Guideline led for Hepatic

Encephalopathy

Rilpivirine HIV infection NHS England Y

Riociguat Pulmonary Hypertension NHS England Y

Ritonavir HIV infection NHS England Y

Rituximab

ABO-incompatible kidney

transplants NHS England Y

Rituximab ANCA - positive vasculitis NHS England Y

NICE TA 308; NHS England Policy:

A13/P/a

Rituximab Cancer services NHS England Y

NICE TA65, TA137, TA174, TA193,

TA226,

Rituximab Graft versus host disease NHS England Y

Rituximab Haemophilia NHS England - requires IFR Y TA243; & NHS England CDF letter

Rituximab

Idiopathic Membranous

Glomerulonephritis

Rituximab Interstitial lung disease NHS England N

Rituximab Myositis NHS England - requires IFR Y

Rituximab Nephritis NHS England - requires IFR Y

Rituximab Neuromyelitis optica NHS England Y

Rituximab



Rituximab Rheumatoid arthritis in adults CCG Y

Rituximab SLE NHS England Y NHS England Policy: A13/PS/a

Romiplostim platelet disorders CCG Y TA221

Ruxolitinib Cancer services CDF Y

Safinamide Parkinsons Disease CCG y

Sapropterin Metabolic disorders NHS England - non-formulary Y NHS England Policy: E12/P/a

Sarilumab Rheumatoid arthritis in adults CCG Y NICE TA 485

Saquinavir Mesylate HIV infection NHS England Y

Sativex

Spasticity associated with

multiple sclerosis Non-formulary - requires IFR Y

Secukinumab Dermatology in adults CCG Y TA350

Sermorelin Acetate

hypthalamic hormones

specialist investigation CCG N

Sertindole antipsychotic - unlicensed CCG Y

Sevelamer Renal dialysis


repatriate Y

NHS England Policies: A11/P/b &

A11/PS/a

Sildenafil Pulmonary Arterial NHS England Y

Simeprevir Hepatitis C NHS England Y

Sirolimus Transplant immunosuppression


repatriate Y

Sodium chloride 7% nebulised

solution Cystic fibrosis CCG N

Sodium chloride oral solution Hyponatraemia -unlicensed CCG Y

Sodium clodronate Cancer services NHS England N supportive therapy

Sodium oxybate Narcolepsy NHS England - requires IFR Y

Sodium Phenylbutyrate Metabolic disorders NHS England - non-formulary Y

Sodium phosphate oral solution

Hypophosphataemia -

unlicensed CCG Y

Sofosbuvir hepatitis C NHS England Y

Sofosbuvir with Daclatasvir/Ledipasvir

Hepatitis C hepatitis C NHS England - non-formulary Y NHS England Policy: A02/PS/b

Sofosbuvir/Valpatasvir/ Voxilaprevir

(Vosevi) Hepatitis C NHS England Y

Somatropin growth hormone CCG Y

Red for children but

Amber for Adults

Sorafenib Cancer services CDF Y

Stavudine HIV infection NHS England Y

Stiripentol Paediatric neurology CCG Y

Streptomycin TB CCG Y

Sunitinib Cancer services NHS England and CDF Y TA169,TA179

Tacrolimus Transplant immunosuppression


repatriate Y

Tadalafil

Pulmonary Arterial

Hypertension NHS England Y

NHS England Policies: A11/P/b &

A11/PS/a

Taliglucerase alfa Metabolic disorders NHS England - non-formulary Y Highly specialised criteria

Taurolock short bowel / high output NHS England Y

Tegafur with uracil Cancer services NHS England Y

Tegafur/Gimeracil/Oteracil Cancer services NHS England Y

Teicoplanin infusion Cystic fibrosis NHS England - requires IFR Y

Telaprevir hepatitis C NHS England Y TA252

Telbivudine Hepatitis B NHS England - requires IFR, non-formulary Y TA154

Temozolamide Cancer services NHS England Y

Temozolomide Endocrinology NHS England - requires IFR Y

Temsirolimus Cancer services CDF Y

Tenofovir Disoproxil Hepatis B NHS England Y

Tenofovir Disoproxil HIV infection NHS England Y

Teriflunomide Multiple sclerosis NHS England Y


D04/P/b

Teriparatide osteoporosis CCG Y

Tetracosactide anterior pituarity hormone CCG N

Tetrahydrobiopterin Metabolic disorders NHS England - non-formulary N

Tezacaftor/Ivacaftor Cystic fibrosis NHS England N

Thalidomide Cancer services NHS England Y TA 228

Thalidomide Chronic cough - unlicensed CCG - requires IFR Y

Theobromine Chronic cough - unlicensed CCG Y

Thyrotrophin

hypothalamic and pituaritary

hormones CCG N

Tiabendazole Antihelmintic CCG N


o/p

Tinzaparin Dialysis - prevention of clotting NHS England Y

Tinzaparin

Treatment / prophylaxis DVT /

PE CCG Y


o/p (same as dalteparin)

Tioguanine Cancer services NHS England Y

Tipranavir HIV infection NHS England - non-formulary Y

Tisseel As per licence CCG Y

Tobramycin Bronchiectasis CCG Y

Tobramycin Cystic fibrosis


repatriate Y


A01/PS/a

Tocilizumab Juvenile arthritis NHS England Y TA238

Tocilizumab Large cell vasculitis NHS England - requires IFR Y

Tocilizumab

Paediatric indications when


Tocilizumab Rheumatology in adults CCG Y TA247

Tofacinitib (Xeljanz) Severe Arthritis NHS England NICE TA480

Tolvaptan

Autosomal Dominant Polycyctic

Kidney Disease Y TA358

Tolvaptan hyponatraemia NHS England - requires IFR Y

Topotecan cancer services NHS England Y

Trabectedin Cancer services NHS England Y

Trastuzumab Cancer services NHS England Y TA458

Treosulfan Cancer services NHS England Y

Tretinoin Cancer services NHS England Y

Trifluothymidine eye drops Eye infection - unlicensed CCG N

Trimetinib with dabrafenib Cancer services NHS England Y

Ustekinumab Psoriasis CCG Y TA180, TA313

Ustekinumab/Stellara Injection Chrones Disease NHS England y TA456

Valganciclovir Cytomegalovirus NHS England Y

Vancomycin eye drops Eye infection - unlicensed CCG N

Vandetanib Cancer services NHS England CDF

Vedolizumab Gastroenterology in adults CCG Y TA342

Velaglucerase alfa Metabolic disorders NHS England - non-formulary Y Highly specialised criteria

Vemurafenib Cancer services NHS England Y TA259

Venetoclax Cancer Services NHS Englan CDF TA487

Vinblastine Sulphate cancer services NHS England Y

Vincristine Sulphate cancer services NHS England Y

Vindesine Sulphate cancer services NHS England Y

Vinorelbine cancer services NHS England Y

Vismodegib Cancer services NHS England CDF TA489

Vitamin A oral solution Vitamin deficiency CCG Y

Voriconazole Antifungal drugs NHS England Y

Voriconazole Chronic pulmonary aspergillosis NHS England Y Highly specialised criteria

VSL#3 Treatment of pouchitis CCG Y

Zepatier(Elbasvir/Grazoprevir) Chronic Hepatitis C

Ziconotide Acetate Intracthecal analgesia NHS England - requires IFR, non-formulary Y

Zidovudine HIV infection NHS England Y

Zoledronic Acid Cancer services NHS England N supportive therapy

Zoledronic Acid Endocrinology CCG N

rech arge drug indication / specialty … indication / specialty commissioned by rech arge y/n...

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