rationale of periodontal treatment
TRANSCRIPT
Rationale of Periodontal Rationale of Periodontal TreatmentTreatment
by
Dr. Marcel Hallare
The effectiveness of periodontal therapy is made possible by the remarkable healing capacity of the periodontal tissue
Properly performed, periodontal Properly performed, periodontal treatment can be relied on to treatment can be relied on to accomplish the following:accomplish the following:
1. eliminate pain
2. eliminate gingival inflammation and gingival bleeding
3. reduce periodontal pockets and eliminate infection
4. stop pus formation
5. arrest the destruction of soft tissue and bone
6. reduce abnormal mobility
7. establish optimal occlusal function
8. restore tissue destroyed by disease in some instances
9. reestablish the physiologic gingival contour necessary for preservation of periodontal health
10.prevent the recurrence of disease
11.reduction of tooth loss
Local TherapyLocal Therapy
The cause of periodontitis and gingivitis is bacterial plaque accumulation on the tooth surface in close proximity to gingival tissue
The accumulation of plaque can be The accumulation of plaque can be favored by a variety of local factors:favored by a variety of local factors:
1. calculus
2. overhanging margins of restorations
3. food impaction
The removal of plaque and all the factors that favor its accumulation is therefore the primary consideration in local therapy
Systemic TherapySystemic Therapy
Systemic therapy may be employed Systemic therapy may be employed as an adjunct to local measures as an adjunct to local measures and for specific purposes such as:and for specific purposes such as:
1. the control of systemic complications from acute infections
2. chemotherapy to prevent harmful effects of posttreatment bacteremia nutritional
3. supportive nutritional therapy4. the control of systemic diseases that
aggravate the patient’s periodontal condition
Systemic therapy for treatment of the periodontal condition and in conjunction with local therapy is indicated in localized and generalized aggressive periodontitis
In these diseases, systemic antibiotics are used to completely eliminate the bacteria that invade the gingival tissues and can repopulate the pocket after scaling and root planing
In studies, Nonsteroidal anti-inflammatory drugs such as flubiprofen and ibuprofen can slow down the development of experimental gingivitis, as well as the loss of alveolar bone in periodontitis
These drugs are propionic acid derivatives and act by inhibiting the cyclooxygenase pathway of anachidonic acid metabolism, thereby reducing prostaglandin formation
Administered orally or applied topically
Future treatment modalities may attempt not to control the bacterial cause of disease, but also suppress the self-destructive components of the host inflammatory response.
FACTORS THAT FACTORS THAT AFFECT HEALINGAFFECT HEALING
In the periodontium, as elsewhere in the body, healing is affected by local and systemic factors
Local FactorsLocal Factors
Systemic conditions that impair healing may reduce the effectiveness of local periodontal treatment and should be corrected before, or along with, local procedures
Healing may be delayed by:Healing may be delayed by:
1. excessive tissue manipulation during treatment
2. trauma to the tissues
3. presence of foreign bodies
4. repetitive treatment procedures that disrupt the orderly cellular activity in the healing process
An adequate blood supply is needed for the increased cellular activity during healing
If this is impaired or insufficient, areas of necrosis will develop and delay the healing process
Healing is improved by debridement, immobilization of the healing area, and pressure on the wound
Systemic FactorsSystemic Factors
Healing capacity diminishes with age, probably due to atherosclerotic vascular changes, which is common in aging and result in reduction of blood circulation
Healing is delayed in patients with generalized infections and in those with diabetes and other debilitating diseases
Healing is retarded by insufficient food intake; bodily conditions that interfere with the use of nutrients; and deficiencies in vitamin C, proteins, and other nutrients
Healing is also affected by hormones
Systemically administered glucocorticoids such as cortisone hinder repair by depressing the inflammatory reaction or by inhibiting the growth of fibroblast, the production of collagen, and the formation of endothelial cells
Systemic stress, thyroidectomy, testosterone, adrenocorticotropic hormone, and large doses of estrogen suppress the formation of granulation tissue and retard healingProgesterone increases and accelerates the vascularization of immature granulation tissue and appears to increase the susceptibility of the gingiva to mechanical injury by causing dilation of the marginal vessels
HEALING AFTER HEALING AFTER PERIODONTAL PERIODONTAL
THERAPYTHERAPY
The basic healing processes are the same following all forms of periodontal therapy
They consist of the removal of degenerated tissue debris and the replacement of tissue destroyed by disease
Regeneration, repair, and new attachment are aspects of periodontal healing
RegenerationRegeneration
Regeneration is the growth and differentiation of new cells and intercellular substances to form new tissues or parts
It takes place by growth from the same type of tissue that has been destroyed or from its precursor
In the periodontium, gingival epithelium is replaced by epithelium, and the underlying connective tissue and periodontal ligament are derived from connective tissue
Bone and cementum are not replaced by existing bone or cementum but by connective tissue, which is the precursor of both
Undifferentiated connective tissue cells develop into osteoblasts and cementoblasts, which form bone and cementum
Regeneration of the periodontium is a continuous physiologic process
Under normal conditions new cells and tissues are constantly being formed to replace those that mature and die
This is termed wear and tear repair
It is manifested by mitotic activity in the epithelium of the gingiva and the connective tissue of the periodontal ligament, by the formation of new bone, and by the continuous deposition of cementum
Regeneration is also going on during destructive periodontal disease
Most gingival and periodontal diseases are chronic inflammatory processes and, as such, are healing lesions
Regeneration is part of the healing
However, bacteria and bacterial products that perpetuate the disease process and the inflammatory exudate they elicit are injurious to the regenerating cells and tissues and prevent the healing from proceeding to completion
By removing bacterial plaque and creating the conditions to prevent its new formation, periodontal treatment removes the obstacles to regeneration and enables the patient to benefit from the inherent regenerative capacity of the tissue
RepairRepair
Repair simply restores the continuity of the diseased marginal gingiva and reestablishes a normal gingival sulcus at the same level on the root as the base of the preexistent periodontal pocket
This process, called healing by scar, arrests bone destruction without necessarily increasing bone height
Restoration of the destroyed periodontium involves mobilization of epithelial and connective tissue cells into the damaged area and increased local mitotic divisions to provide sufficient number of cells
New AttachmentNew Attachment
It is the embedding of new periodontal ligament fibers into new cementum and the attachment of the gingival epithelium to a tooth surface previously denuded by disease
Epithelial adaptation is the close apposition of the gingival epithelium to the tooth surface without complete obliteration of the pocket
The pocket space does not permit passage of the probe
These deep sulci lined by long, thin epithelium may be as resistant to disease as true connective tissue attachment
The absence of bleeding or secretion on probing, the absence of clinically visible inflammation, and the absence of stainable plaque on the tooth surface when the pocket wall is deflected from the tooth may indicate that the “deep sulcus” persists in an inactive state, causing no further loss of attachment
Post-therapy depth of 4 or even 5mm may therefore be acceptable in these cases
New attachment and osseous regeneration have been a constant but elusive goal of periodontal therapy
Melcher pointed out that the regeneration of the periodontal ligament is the key to new attachment because it “provides continuity between the alveolar bone and the cementum and also because it contains cells that can synthesize and remodel the three connective tissues of the alveolar part of the periodontium”
During the healing stage of a periodontal pocket, the area is invaded by cells from four different sources: oral epithelium, gingival connective tissue, bone, and periodontal ligament
The final outcome of periodontal pocket healing depends on the sequence of events during the healing stages
If the epithelium proliferates along the tooth surface before other tissues reach the area, the result will be a long junctional epithelium
If the cells from the gingival connective tissue are the first to populate the area, the result will be fibers parallel to the tooth surface are remodeling of the alveolar bone with no attachment to the cementum
If bone cells arrive first, root resorption and Ankylosis may occur
Only when cells from the periodontal ligament proliferate coronally is there new formation of cementum and periodontal ligament
The EndThe End