rapid synthesis of arylpiperazine derivatives for imaging 5-ht1a receptor under microwave...

2006 Pyrazine derivatives R 0550 Rapid Synthesis of Arylpiperazine Derivatives for Imaging 5-HT 1A Receptor under Microwave Irradiation. — A three-step synthesis of piperazine derivatives (VI) is presented in which microwave irradiation is employed in every step. By com- parison with conventional heating it is shown that microwave yields are considerably higher and reaction times are considerably shorter. — (PARK*, S. H.; GWON, H. J.; LEE, H. S.; PARK, K. B.; Bull. Korean Chem. Soc. 26 (2005) 11, 1701-1705; Div. Radioisot. Appl., Korea At. Energy Res. Inst., Taegeon 305-353, S. Korea; Eng.) — M. Bohle 14- 166

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Page 1: Rapid Synthesis of Arylpiperazine Derivatives for Imaging 5-HT1A Receptor under Microwave Irradiation

2006

Pyrazine derivativesR 0550 Rapid Synthesis of Arylpiperazine Derivatives for Imaging 5-HT1A Receptor

under Microwave Irradiation. — A three-step synthesis of piperazine derivatives (VI) is presented in which microwave irradiation is employed in every step. By com-parison with conventional heating it is shown that microwave yields are considerably higher and reaction times are considerably shorter. — (PARK*, S. H.; GWON, H. J.; LEE, H. S.; PARK, K. B.; Bull. Korean Chem. Soc. 26 (2005) 11, 1701-1705; Div. Radioisot. Appl., Korea At. Energy Res. Inst., Taegeon 305-353, S. Korea; Eng.) — M. Bohle

14- 166

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