STRATEGIC REPORT

EUROPEAN ORTHOPAEDIC

MARKET2018-2023

H I P , K N E E & S H O U L D E R

May 2019 – 16th Editionw w w. av i c e n n e . c om

AVICENNE’S

UNIQUE WARRANTY

If you are not 100% satisfied with our

report, send it back to us with a letter indicating

the reasons and we will refund you in full!PUBLISHED MAY 2019 • 16TH EDITION

Special focus on the Worldwide

orthopaedic market, player dynamics

and global market shares

NEW

OVER 25 YEARS OF STRATEGIC CONSULTANCY FOR THE MEDICAL DEVICE INDUSTRY

AVICENNE HAS BEEN INVOLVED IN THE MAIN EUROPEAN ORTHOPAEDIC DEALS OVER THE PAST 25 YEARS

Creation of AVICENNE

DePuy-Landanger

deal

CARLYLE-Marle deal

AXA PE - LIMA deal

Keensight- Menixdeal

APAX- Amplitude

dealLISI entering

Orthopaedics

Charlesbank- TECOMET

deal

1992

IMPLANTS conference :1rst edition

2005 2009 2012

20131997 2007 2011

2014

2016

TECRESAAP Biomaterials

2017

Biomaterials

2018

International conference on innovation & solutionsfor orthopaedic implants and orthobiologics

EURAZEOIN’TECH deal

BradshawIN’TECH deal

STRATEGIC MARKET RESEARCH, DIVERSIFICATION AND FINDING TARGETS FOR ACQUISITION: EXAMPLE OF MISSIONS

Key Opinion Leaders surveys

Customized Strategic research

Build up& Target research

Management team assessment

Strategic & Commercial Due

Diligence

VendorDue Diligence

Key Opinion Leader’s usage & preferences

for orthopaedic products

Survey for opportunities &

risks of launching new products

Company reputation survey

with surgeons

Diversification

Market entry

Geographic expansion

New Product assessment & launch

Worldwide Market shares tracking for emerging products

Screening & Identification of potential targets

TargetAssessment

Introduction &Initial discussions

Strengths & Weaknesses of

management team

Identification of suitable candidates

to strengthenManagementcapabilities

Formal Due Diligence based

upon: interviewingindustry experts &

competitors

Product portfolio assessment

Customer portfolio analysis

Manufacturing organization

assessment & site visits

Routes to create value

Sizing and market dynamics

Detailed market analysis and

positioning of the company

Management interviews

Company differentiation &

keys to grow market share

Business Plan

Transaction Services Strategic Market Research

STRATEGIC & COMMERCIAL DUE DILIGENCE: EXAMPLE OF MISSIONS

IN’TECH Medical

was acquired by

EURAZEO PME

June 2017

Avicenne advisedthe Buyer

TECOMET

was sold by

Charles Bank

April 2013

Avicenne advisedthe Buyer

AAP Biomaterials

was acquired by

Keensight Capital & TECRES

May 2016

Avicenne advisedthe Buyer

Bradshaw

was acquired by

IN’TECH MEDICAL

June 2018

Avicenne advisedthe Buyer

LIMA

was acquired by

Ardian

September 2012

Avicenne advisedthe Buyer

AMPLITUDE

was acquired by

Apax

April 2011

Avicenne advisedthe Buyer

MARLE

was acquired by

Carlyle

April 2009

Avicenne advisedthe Buyer

MENIX GROUP

was acquired by

Keensight Capital

April 2014

Avicenne advisedthe Buyer

Implants

Hip

Knee

Spine

Extremities

Trauma

METHODOLOGY: WHY CHOOSE THIS REPORT?

HIP, KNEE & SHOULDER DETAILED SEGMENTATION USED

SURVEY METHODOLOGY

OEM and Contract Manufacturer direct interviews with decision makers thanks to strong links with CEOs, R&D, Marketing, Sales...

Cross-checking of information thanks to our tried and tested operating models

OEM

Hip

Knee

Shoulder

IMPL

ANTS

ZIMMER STRYKER DEPUY SYNTHES

Vol Vol Vol

Y

Val Val ValRowth % %

DEPUY SYNTHES

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MM

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Sour

ce 1

: con

tact

1

Sour

ce 1

: con

tact

2

Sour

ce 3

: mar

ketin

g

Sour

ce 4

: Pr

oduc

t Man

ager

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: Sa

les M

anag

er

…

Worldwide coverage

DEVELOPED COUNTRIES

BRICCOUNTRIES

DEVELOPING COUNTRIES

Latin America, Middle East, Asia

Western Europe+

25+ years of historical data on the Orthopaedics and Contract Manufacturing markets

Companies and continuous tracking

Highly detailed segmentation

Entire supply chain and all players: OEMs, Contract Manufacturers

All product types: implants, instruments, cases and trays, biologics, cements, ceramics

All manufacturing services: forging, casting, machining, coating, packaging, sterilization

Operating Models & Cross-checking of information

Implants Instruments Cases and trays Biologics

Contract Manufacturing

Fixations for Total hip

Cemented(Stem & cup are

cemented)

Metal / Polyethylene

Posterior stabilized

Metal / Polyethylene

Metal / Polyethylene

Bearings for Cemented

Total Knee

Bearings for Cementless

Bearings for Hybrid

Monobloc

Dual mobility cup

Standard With bipolar shell

HIP GENERAL SEGMENTATION

HIP SEGMENTATION BY FIXATIONS AND BEARINGS

KNEE SEGMENTATION BY FIXATIONS AND BEARINGS

Anterior approach

Postero/lateral approach

Total

Total Fixed

Fixed Mobile

Revision

Revision

Partial

HIP

KNEE Fixations for Total Knee

ResurfacingModular

Cemented Cementless Hybrid

Shorter stem & mini hip

Revision

Primary

Cementless(Stem & cup

are cementless)

Ceramic / Polyethylene

Cruciate retaining

Ceramic / Polyethylene

Ceramic / Polyethylene

Ceramic / Ceramic

Ceramic / Ceramic

Partial Mobile

CementedCemented

Total

Standard Reversed

Universal stems Revision Resurfacing

SHOULDER Mini shoulder

Partial

Cemented CementedCementless CementlessHybrid Hybrid

CementlessCementless

HybridHybrid

Unicondylar Femoro patelar

KNEE GENERAL SEGMENTATION

SHOULDER GENERAL SEGMENTATION

Hybrid(Stem is

cemented, cup is

cementless)

YOU WILL FIND IN THE REPORT:

GENERAL DATA ON COUNTRIES HEALTHCARE SYSTEMS

820 Pages – 1,550 Exhibits

Highly detailed segmentation: Total, Revision, Partial – Cemented, Cementless, Hybrid - Metal/Polyethylene, Ceramic/Polyethylene, Ceramic/ Ceramic for hips - Fixed, Mobile for knees - Standard, Reversed for shoulders, etc.

5 main European countries analyzed in detail: Germany, UK, France, Italy, Spain

12 other countries, also analyzed to get accurate picture of entire European market: Belgium, Denmark, Finland, Sweden, Ireland, Netherlands, Austria, Luxembourg, Greece, Portugal, Switzerland & Norway

USA, China, South Korea, Australia, Japan: Hip & knee units and value in 2018 and 2023 forecast

Analysis of the drivers & limiters of the market, price pressure and regulatory trends

Comprehensive analysis of the key companies and their market share

KNEE

40+ companies analyzed plus market shares

detailed

SHOULDER

20+ companies

analyzed plus market shares detailed

HIP

45+ companies analyzed plus market shares detailed

DETAILS OF ALL SEGMENTS

MARKET SHARE PER COUNTRY, PER PLAYER AND FOR HIP,

KNEE & SHOULDER

2023 FORECASTS FOR ALL THE SEGMENTS & SUB-SEGMENTS

High growth productsD E TA I L E D I N R E P O RT

> Hip dual mobility,> Mini hip & Shorter hip stem,

> Anterior surgical hip approach,> Trabecular metal usage

for hip, knee & shoulder

Download the detailed table of contents

www.avicenne.com

O R D E R F O R MEUROPEAN ORTHOPAEDIC MARKET

2018-2023H I P , K N E E & S H O U L D E R

Published May 2019 – 16th Edition

CUSTOMER INFORMATIONFirst name: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Name: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Job title: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Company: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Email: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Address: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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City/Country: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Phone: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Fax: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Intra-community VAT Number (Mandatory for EU companies): . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

PAYMENTTotal € (from above): . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Purchase order number (if applicable): . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Accounting dept. address (if different than company address): . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Date, Signature (mandatory)

PRODUCT OPTIONSPlease select:

Full report (pdf) European orthopaedic Market 2018-2023 / Hip, Knee & Shoulder market report 5 main countries + Rest of Europe (12 countries) and all products (Hip & Knee & Shoulder) • 820 pages / 1,550+ exhibits • Single-user licence: 5,900 €

1 country report (pdf) Selected from Ger, UK, Fr, It, Sp or other country with all products - Please specify country: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . • 130 pages / 250+ exhibits • Single-user licence: 3,900 €

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STRATEGIC REPORT

EUROPEAN ORTHOPAEDIC

MARKET2018-2023

H I P , K N E E & S H O U L D E R

CLIENTS

EUROPEAN ORTHOPAEDIC MARKET 2018-2023

H I P , K N E E & S H O U L D E R

Published May 2019 – 16th Editionco

mpa

nies

Ort

hopae

dics manufacturers

Contract

Private Equities

& financial services Consulti

ng firm

s

Aesculap-B Braun, Amplitude, Aston Medical, Bioland, Biomet, Biomicron, Ceraver,

Cousin-Biotech, Dedienne, Depuy Synthes, Eurospine, Evolutis, Exactech, FH, FX Solutions,

Geistlich, Help Ortho, Implanet, Implant Industries, Integra Life Sciences, Kisco International, Lepine, Lima, Mathys, Medtronic, MBA, Medacta, Nexis,

OST, Ortho Baltic, Orthosoft, Ossacur, Osteotech, Plus Ortho, Progenor, SEM, Seremm, Scient’x, Smith

& Nephew, SME, SMI, Stryker Corp, Stryker Limerick, Stryker Spine, Spineway, SGM-Codim,

Stanmore Implants, Stryker, Summit Medical, Surgical Devices Pty, Symbios, Tornier now Wright

Medical, Transtructure, Transysteme, Zimmer Biomet, Wright Tornier, X’Nov…

Apax Partners, Altor Equity Partners, Alpha Associés Conseil, Ardian, Argos Soditic, Banque Lazard, BIP

Investment Partners, Capzanine, Carlyle Group, Charlesbank Capital, Clayton Dubilier & Rice, CM-CIC

Investissement, EKKIO Capital, Eurazeo PME, European Capital, Goldman Sachs, Keensight Capital,

LBO France, NATIXIS Partners, PAI Partners, Permira, Piper Jaffray, Pragma Capital (now Sparring Capital),

Rothschild Five Arrows, Simuval, Tikehau, Tinicum, UI Gestion, Warburg Pincus, Zurmont Madison…

Autocam Medical, Addup Solutions, Avalign Technologies, Ceramtec, Cetim, EOS, Eurocoating, Finetubes, Forginal, Geoffroy, Integer-Greatbatch now Viant, HWG, In’tech Medical, Inomed Technology, Invibio Victrex, Ionbond, Jabil Medical, Jenoptik, Heptal, Komet, LISI Medical, Manoir Industries, Marle, Mediliant, Medin Technologies, Metal Craft & Riverside, Nowak, Nypro, Oerlikon, One Ortho, Orchid Orthopedic Solutions, Paragon Medical, PolymerExpert, Projection Plasma System, Sandvik, Seabrook Medical, Stainless, Straits Orthopedics, Somepic, Surgical Devices Pty, Symmetry Medical, Tecomet, TE Connectivity, Terolab Surface Medical, Vaccucast, VSMPO Tirus, Wichard, Willemin Macodel, Zollern,…

Arthur D. Little, AT Kearney, Alvarez et Marsal, Bain & Company, Boston Consulting Group, BC Partners, Health Advances, KPMG Strategy, LEK Consulting, McKinsey & Company, OC&C Strategy, Oliver Wyman, Roland Berger…

Avicenne is also the creator of IMPLANTS, a worldwide conference focusing on Strategy, Innovation & Regulatory in the orthopaedic world. The 2018 and 14th edition of IMPLANTS attracted more than 150 international decision-makers for 2 days of presentations, tutorials and business networking. The speakers highlighted how manufacturing techniques and purchasing strategies are evolving, how Robotics and Additive Manufacturing will alter the future landscape and how to cope with Regulatory burdens.

www.implants-event.com

PARIS / FRANCE

Created and chaired by

International conference on innovationfor orthopaedic implants and orthobiologics

2 0 19

S I N C E 2 0 0 515