r egrowing hair with laser and light sources: is this practical?
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R egrowing hair with laser and light sources: Is this practical?. Michael R Hamblin PhD. Mechanisms of low-level light therapy. growth factor production. extracellular matrix deposition . near infrared light. cell proliferation & motility anti-apoptosis and pro-survival. Gene - PowerPoint PPT PresentationTRANSCRIPT
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Regrowing hair with laser and light sources: Is this practical?
Michael R Hamblin PhD
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near infrared light extracellular matrix deposition growth factor production
cell proliferation & motilityanti-apoptosis and pro-survival
Gene transcriptionsignaling
Mechanisms of low-level light therapy
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Literature Review
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Low Level Light Therapy for Hair Regrowth
1. Does it work in androgenetic alopecia?2. What is best wavelength?3. What is best fluence/irradiance?4. Do you need a laser?5. How often should light be repeated?6. Other parameters - pulsing, polarization?7. Does it work for alopecia areata?8. Does it work in women?9. Does it work for chemotherapy?
10. What is best way to deliver light?
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655nM+/-5nm 26mW +0 -15%
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Summary and conclusionLow level light mechanisms are beginning to be understood
Evidence exists for laser-induced hair growth
Follicles can be rescued from dying and stimulated into anagen
Optimum wavelength, laser or LED, irradiance, fluence and treatment repetition need to be determined
Different patients may need different dosimetry
Plethora of devices appearing on market
Minimal number of clinical studies