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QUICK AND EASY LAB SAMPLE PREP FOR GCMSMS AND LCMSMS MULTIRESIDUE PESTICIDE ANALYSIS

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Page 1: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

QUICK AND EASY LAB SAMPLE PREP FOR GCMSMS AND LCMSMS MULTIRESIDUE PESTICIDE ANALYSIS

Page 2: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety of matrices such as fruits, ve-getables, meat products, fruit juices, wine, spices, cereals, ho-ney, dried fruit. By means of this treatment one can detect analytes as pesticides, mycotoxins, veterinary drugs, acryla-mides, antibiotics, polycyclic aromatic hydrocarbons, etc.The method based on a paper published in 2003 by the US Department of Agriculture - Eastern Regional Research Center - in Wyndmoor, PA (M. Anastassiades, S.J. Lehotay, D. Stajnbaher, F.J. Schenck) admirably replaces old extraction methods drastically reducing execution and costs arising from: solvents, glassware and special laboratory equipment.Method “Original” of 2003 has been joined by the methods AOAC 2007.01 and EN 15662 approved by European and American Food Regulatory Agencies that are surely the most used and disseminated.

PROCEDURE INVOLVING TWO PHASES

Deriving from the first step, the organic phase (acetonitrile extract) comes in contact with other typical clean up sorbents: pri-mary and secondary amine (PSA), graphitized carbon black (GCB) or C18 with the purpose of removing sugars, lipids, sterols, organic acids, proteins, carotenoids, chlorophyll and other pigments in addition to the residual water by the use of magnesium sulfate. After that it follows shaking and centrifugation. The anhydrous acetonitrile phase is ready for analysis in GCMS / MS directly (LVI) or after exchange of solvent, while the injection LCMS / MS is ready after sample dilution with mobile phase.

The analytes are extracted from the matrix by the use of acetonitrile and different types of salts and buffers. After the partition liquid-liquid (LLE) it follows: shaking, centrifugation and collection of acetonitrile phase.

DISPERSIVE SOLID PHASE (d-SPE)

EXTRACTION (LLE)

PRODUCTS WITH LOW WATER CONTENTThe extraction QuEChERS is designed primarily for food products with a high water content but it also applies to dried foods by adding during comminution step, weighted amount of water depending on the type of sample as defined in the CEN Guidelines.

FRUITS ANDVEGETABLES

10 g 10 g 5 g 5 g 5 g 2 g

none X* g 10 g 7,5 g 10 g 10 g

WEIGHT OFSAMPLE

WATERADDED

8 g

2 g

* X = 10 g - water amount in 10 g of sample. ** Water may be added during shredding step of the initial sample.

FRUITS ANDVEGETABLES

CEREALS(WHEAT, CORN,OATS, BARLEY,

ETC.)

NUTS(HAZELNUTS,ALMONDS,PISTACHIOS,

ETC.)**

HONEY OLIVEOIL

SPICES(PEPPER,PAPRIKA,

ETC.)

ISO/IEC 17025:2005 ISO Guide 34:2009UNI EN ISO14001:2004UNI EN ISO9001:2008

WITH MORETHAN 80% OF WATERCONTENT

WITH WATERCONTENTBETWEEN

25% AND 80%

* ISO is a trademark of the International Standards Organization.

WHAT IS ?

Page 3: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

PRODUCTS

The line of products branded is the most completed line on the market. It was realized in every possible variant of packaging “Ready to Use” (conical tubes, self-standing tubes, packets, etc.) and in different wording so as to satisfy all the official methods (EN 15662, AOAC 2007.01, etc.). The raw materials are selected and analyzed for each batch in the laboratory accredited to ISO / IEC 17025: 2005. Each batch of Falcon tubes, test tubes and caps are subjected to checks as leak and release tests.Each production lot of the is accompanied by a certificate of analysis showing the traceability of components and traceability of the analytical data as well as a safety data sheet complies with the REACH Reg. (EC) 1907/2006.

SOME GOOD REASONS TO CHOOSE PRODUCTS

Cleaner extractsfrom cleaner products

Excellent lot to lot reproducibility

d-SPE clean up improves ms

spectral library matches

Product code batch number color code

barcode identification

Higher recoveries for all classes of analytes

Better peak shape results in more

accurate quantification

Closely Related to

Estimated time to process 20 samples 400 min

Pure solvent used 1200 - 1800 ml

Chlorinated waste 400 - 600 ml

Glassware and specialized laboratory equip-ment and disposable materials

Capacity for 200 ml, quartz wool, funnel, water bath or evaporator

80 min

200 ml

0

MicropipetteCentrifuge

Estimated time and materials to process 20 samples/day

Traditional Extraction Method(mini-Luke-or Modified Luke Methods)

QuEChERSMethod

Savings with QuEChERS Prod

5x faster

6÷9x less solvent

safer, cheaper, greener

is READY TO USE

*Estimate for a laboratory performing analysis multiresidual 1200 per year of pesticides in food matrices with method EN 15662

CHOOSE PRODUCTS AND SAVE TILL €10.000/YEAR

Page 4: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

CHOOSING A dSPE SORBENT

PSA is the base sorbent used for QuEChERS clean-up (dSPE tube) because removes substances

that might act as instrumental interferences.

In addition to PSA, C18 removes lipids and non polar interferences.

REMOVEsugar, fatty acids, organic acids,

anthocyanine pigments

REMOVElipids, non polar interferences

REMOVEpigments, sterols, non polar interferences

PSAPrimary and secondary amine

C18Octadecyl

GCBGraphitized carbon black

GCB removes pigments that can degrade GCMS performance but EN15662 recommends less GCB because can have a negative ef-fect on the recoveries of certain pesticides like : Chlorothalonil, Per-methrin, Deltamethrin, Coumaphos ,Thiabendazole, Quintozene, etc.

Further Information: Additional information useful to the analyst planning QuEChERS analysis may be found to the following website:

For each type of matrix you can choose the most appropriate d-SPE. Tubes d-SPE with MgSO4 and PSA effectively remove polar organic acids, sugars, anthocyanine, lipids and sterols. Some fruits and vegetables (spinach, red peppers, carrots, etc.) with a high content of non-polar pigments such as carotenoids, chlorophyll, etc. require d-SPE with graphitized carbon black (GCB) for the discoloration. The elimination of pigments is necessary to avoid accumulations in the liners of GC’s injector.

Bibliography: (1) Fast and easy multiresidue method employing acetonitrile extraction/partitioning and “dispersive solid-phase extraction” for the determination of pesticide residues in produce. J. AOAC Interna-tional 86 (2003) 412. M. Anastassiades, S.J. Lehotay, D. Stajnbaher, F.J. Schenck. (2) AOAC Official Method 2007.01 Pesticide Residues in Foods by Acetonitrile Extraction and Partitioning with Magnesium Sulfate. (3) EN 15662 November 2008. Foods of plant origin - Determination of pesticide residues using GC-MS and/or LC-MS/MS following acetonitrile extraction/partitioning and clean-up by dispersive SPE - QuEChERS-method. (*) Dry commodities must be hydrated in order to improve the extraction.

www.ec.europe.eu/food/plant/protection - www.crl-pesticides.eu/docs/public - www.nal.usda.gov/fnic/foodcomp/search/ - www.quechers.com - www.quelab.it

Depending on the nature of the commodity, cut and/or grind until the homogenization is reached

Weigh 10 g of homogenized/hydrated(*) sample in a 50 ml centrifuge tube

Add 10 ml of ACN

Add ISTD

Shake

Add Cod. Q17B14H093(4 g MgSO4 + 1 g NaCl)

Shake vigorously for 1 min.

Centrifuge for 5 minutesat 5000 rpm

Transfer 1 ml aliquot of supernatant to a disper-sive tube (2 ml), d-SPE, containing

MgSO4 + PSA (plus GCB to remove pigments and C18 to remove fatty compounds and n-polar interferences). Choice the right

d-SPE Tube. (See next page)

Shake for 1 min.

Centrifuge for 1 minute at 6000 rpm

Transfer into vial. Analyze directly or acidify if necessary (LC-MS/MS) or protect with sorbitol and preserve with

toluene (GC-MS/MS). Depending on the nature of the commodity and pesticides see detailed

procedure.

Depending on the nature of the commodity, cut and/or grind until the homogenization is reached

Weigh 15 g of homogenized/hydrated(*) sample in a 50 ml centrifuge tube

Add 15 ml of 1 % HOAc in ACN

Add ISTD

Shake

Add Cod. Q17B15E092(6 g MgSO4 + 1,5 g NaOAc)

Shake vigorously for 1 min.

Centrifuge for 1 minuteat >1500 rcf

Transfer 8 ml aliquot of supernatant to a dispersive tube (15 ml), d-SPE AOAC, containing MgSO4 + PSA (plus GCB to remove pigments and C18 to remove fatty compounds and non-polar interferences). Choice the right

d-SPE Tube. (See next page)

Shake 30 seconds

Centrifuge for 1 minute at >1500 rcf

Transfer into vial. Analyze directly or acidify if necessary (LC-MS/MS) or protect with sorbitol and preserve with

toluene (GC-MS/MS). Depending on the nature of the commodity and pesticides see detailed

procedure.

Depending on the nature of the commodity, cut and/or grind until the homogenization is reached

Weigh 10 g of homogenized/hydrated(*) sample in a 50 ml centrifuge tube

Add 10 ml of ACN

Add ISTD

Shake

Add Cod. Q17B14F091(4 g MgSO4 + 1 g NaCl + 1 g Na3Citrate • 2H2O +

0,5 g Na2HCitrate • 1.5H2O)

Shake vigorously for 1 min.

Centrifuge for 5 minutesat >3000 g

Transfer 6 ml aliquot of supernatant to a disper-sive tube (15 ml), d-SPE EN 15662,

containing MgSO4 + PSA (plus GCB to remove pigments and C18 to remove fatty compounds and non-polar interferences). Choice the right

d-SPE Tube. (See next page)

Shake for 30 seconds(when using GCB 2 minutes)

Centrifuge for 5 minutes at >3000 g

Transfer into vial. Analyze directly or acidify if necessary (LC-MS/MS) or protect with sorbitol and preserve with

toluene (GC-MS/MS). Depending on the nature of the commodity and pesticides see detailed

procedure.

EXTRACTION (LLE)

DISPERSIVE SPE CLEAN-UP

AOAC 2007.01(2)ORIGINAL(1) EN 15662(3)

Page 5: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

FRUITS VEGETABLES

OTHER FOODS

EN/AOACGENERAL

Fats and waxes

EN/AOACEN/AOACPigment

HighPigment

EN

Pigmentsand FatsAOAC

EN/AOACGENERAL

Fats and waxes

EN/AOACEN/AOACPigment

HighPigment

EN

Pigmentsand FatsAOAC

Thiophanate-methylThiabendazole

PropoxurPenconazole

MetalaxylKresoxym-methyl

ImidaclopridEthoprophos

DichlorvosCyprodinil

Azinphos-ethylAcephate

0 40 60 80 100 120

RECOVERY %

PE

STIC

IDE

S

20

AcephateAzinphos-ethylCyprodinilDichlorvosEthoprophosImidaclopridKresoxym-methylMetalaxylPenconazolePropoxurThiabendazoleThiophanate-methyl

111879994949991939099110108

0,321,224,984,264,932,404,673,864,854,744,784,96

RECOVERY %PESTICIDES RSD (n=6)

HIGH RECOVERIES FOR ALL CLASSES OF ANALYTES

Pesticide Recoveries and RSDs obtained by d-SPE Cleanup of apple sample fortified at 100 ng/g using EN 15662 PSA.

Citrus JuicesGrapefruitLemon / LimeOrangeOrange PeelNectarinesTangerineAppleApple, DriedApple SauceApple JuicePearQuinceBlackberryBlueberryCurrantElderGooseberries, RedRed GrapesGreen GrapesRaspberryRaisinsCranberryStrawberryApricotApricots, DriedApricot NectarCherryMirabelleNectarinesPeachFishing, DriedPlumDried PlumPineappleBananaAvocadoOlivesFig, DriedMelonKiwiMangoPapaya

Fish, Honey, Oil, EggsSpices (Pepper, Paprika, etc.)Meat, etc.*Other Method

BeetCarrotCeleriacHorseradishParsley RootRadishSalsifyPotatoGarlicOnionShallotLeekChiveEggplantCucumberGreen PepperRed Bell PepperPumpkinTomatoZucchiniBroccoliBrussels SproutsCauliflowerChinese CabbageKaleKohlrabiRed CabbageSavoy CabbageWhite CabbageVarieties of lettuceEndiveWatercressValerianellaCilantroBasilParsleyArugulaSpinachAsparagusCeleryLeekRhubarbArtichokeBeans, Peas (Fresh)Lentils, Beans (Dry)Wheat, Corn, RiceFlour, Etc.Coffee BeansTea Leaves

*

Page 6: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

APPLICATIONS

SCREENING 135 PESTICIDES IN FAST GC-MSMS

GC CONDITION

Carrier Gas :Injector :

PTV Temp. Program :

ChromLab® Column :

Split :

Transer line Temp :GC Oven program :

He, constant flow 1 ml/minPTV Splitless Mode with Siltek baffled liner 2 mm ID70°C for 0,02 min; 12°C/s to 280°C, 1,2 min; 14,5°C/s to 320°C 6 min, clean flow 80 ml/min5 MS, L: 20 mt - ID: 0,18 mm - F.T.: 0,18µm Cod. CHL-5MS20HS1818Splitless injection, splitflow 50 mL/min at 90”280 °C80° C for 90” - 30° C/min to 210 °C20° C/min to 320 °C - 320°C for 120”

MS CONDITION

Sorce Temp. :Emission Current :

Ionization Mode :Mass Resolution :

Collision Gas :Cycle Time :

Acquisition Mode :Mass table :

Pesticide Stock Solution :

Internal Standard :

Surrogate :

260 °C25 µAEI at 70 eVQ1 and Q3 at 0,7 Da (FWHM)Ar at 1,5 mTorr0,30 sTimed-SRM276 Timed-SRM transition/fas GC run

Multicomponents Kit 135 Pesticides Cod. KIT4T3L135

Malathion d6 Cod. CRM2A2L1285 TPP 100 mg/L Cod. CRM2B3L760

CLEAN-UP/dSPEEXTRACTION LLE EN 15662

4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS

Code : Q1B14F091

900 mg MgSO₄, 150 mg PSA

Code : Q2A22Z391

is closely related to the certified reference materials . There are a variety of standards available: QC

Standard, internal standards, Standard deuterated surroga-tes “ready to use” for the extraction and some kits Multi Components mixtures of pesticides. Consult the catalog

containing over 2000 products on www.labstandard.it

CONTINUITY AND COMPLEMENTARITY WITH THE CRM BRANDED

Moreover, in our catalog, all acces-sories are available for the execu-tion of the method QuEChERS: bottle top dispenser solvent, tube racks, micropipettes, GC and HPLC columns, inlet liners, vials, etc. which can be purchased on e-commerce: www.labinstruments.it

REGISTER ON OUR SITE AND YOU WILL GET AN IMMEDIATE DISCOUNT OF UP TO 40% ON MORE THAN 50.000 ITEM CATALOG

Parathion-Ethyl d10 100 mg/L

Malathion-d6 100 mg/L

Surrogate TPP 100 mg/L

Mix A26 EN 15662 QuEChERS QC Spike

Multi Components Kit 510 Pesticides

Multi Components Kit 218 Pesticides

Multi Components Kit 135 Pesticides

CRM2A2L1409

CRM2A2L1285

CRM2B3L760

CRM3B3L115

KIT4V3L510

KIT4B3L218

KIT4T3L135

CODE

SCREENING 510 PESTICIDES IN LC-HRMS

HPLC CONDITION

Column :Chrom-Lab® C18 :

Flow Rate :

Time:Gradient A%:

B%:

100 x 2,1 - 1.9µm p.z. Cod. CH302-10210,5 ml/min H₂0 with 0,1% formic acid + 4mM ammonium formate CH₃OH with 0,1% formic acid + 4mM ammonium formate 0 1 8 12 12,5 14100 100 0 0 100 100 0 0 100 100 0 0

A

B

MS CONDITION

Mass Range :Resolution :

Automatic Gain Control :

Spray Voltage :Capillary Temperature :

Sheat gas :Auxiliary gas :

Vaporizer Temp. :Pesticide Stock Solution :

Internal Standard :

Surrogate :

100 - 150050.00010 e 6

2200 V280°C32au7au200°C Multicomponents Kit 510 Pesticides Cod. KIT4V3L510 Parathion-ethyl d10 Cod. CRM2A2L1409 TPP 100 mg/L Cod. CRM2B3L760

Mobile Phase :

HEATED ELETTROSPRY IONIZATION SORCE CONDITIONS:

MATERIALS:

CLEAN-UP/dSPEEXTRACTION LLE EN 15662

MATERIALS:

4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS

Code : Q1B14F091

900 mg MgSO₄, 150 mg PSA

Code : Q2A22Z391

Page 7: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

ORDERING INFORMATION

EXTRACTION LLE

KIT CLEAN-UP d-SPE TUBES (15 ml)

KIT CLEAN-UP d-SPE TUBES (2 ml)

Method : EN 15662 d-SPE150 mg MgSO₄, 25 mg PSA150 mg MgSO₄, 25 mg PSA Varian*150 mg MgSO₄, 25 mg PSA, 25 mg C18EC150 mg MgSO₄, 25 mg PSA Varian*, 25 mg C18EC150 mg MgSO₄, 25 mg PSA, 2.5 mg GCB150 mg MgSO₄, 25 mg PSA Varian*, 2.5 mg GCB150 mg MgSO₄, 25 mg PSA, 7.5 mg GCB150 mg MgSO₄, 25 mg PSA Varian*, 7.5 mg GCBMethod : A.O.A.C. 2007.01 d-SPE150 mg MgSO₄, 50 mg PSA150 mg MgSO₄, 50 mg PSA Varian*150 mg MgSO₄, 50 mg PSA, 50 mg C18EC150 mg MgSO₄, 50 mg PSA Varian*, 50 mg C18EC150 mg MgSO₄, 50 mg PSA, 50 mg GCB150 mg MgSO₄, 50 mg PSA Varian*, 50 mg GCB150 mg MgSO₄, 50 mg PSA, 50 mg C18EC, 50 mg GCB150 mg MgSO₄, 50 mg PSA Varian*, 50 mg C18EC, 50 mg GCBMethod : C18 d-SPE Tube150 mg MgSO₄, 25 mg C18Method : Mycotoxins d-SPE Tube 150 mg MgSO₄, 50 mg PSAMethod : PSA/C18/GCB dSPE Tube150 mg MgSO₄, 50 mg PSA, 50 mg C18EC, 7.5 mg GCB

Packaging100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to UsePackaging mg MgSO4, 400 mg PSA100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to Use100 Tubes (2 ml) Ready to UsePackaging100 Tubes (2 ml) Ready to UsePackaging100 Tubes (2 ml) Ready to UsePackaging100 Tubes (2 ml) Ready to Use

CodeQ1C21Z191Q1C21Z691Q1C21A191Q1C21A691Q1C21Z111Q1C21Z611Q1C21Z121Q1C21Z621CodeQ1C21Z292Q1C21Z792Q1C21B292Q1C21B792Q1C21Z252Q1C21Z752Q1C21B252Q1C21B752CodeQ1C21M094CodeQ1C21Z296CodeQ1C21B227

* Varian is a trademark of Varian inc. Palo Alto, CA USA.

Method : EN 15662 Citrate LLE4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4 g MgSO₄, 1 g NaCl, 1 g SCTD, 0,5 g SCTS4,8 g MgSO₄, 1,2 g NaCl, 1,2 g SCTD, 0,6 g SCTSMethod : Original LLE Unbuffered4 g MgSO₄, 1 g NaCl (sample=10g)6 g MgSO₄, 1,5 g NaCl (sample=15g)Method : A.O.A.C. 2007.01 Acetate LLE6 g MgSO₄, 1,5 g NaAcetate6 g MgSO₄, 1,5 g NaAcetateMethod : Acrylamides LLE4 g MgSO₄, 0,5 g NaClMethod : Mycotoxins LLE4 g MgSO₄, 1 g NaCl

Packaging50 Transfer Tubes + 50 empty Tubes (50ml)50 Tubes (50ml) Ready to Use50 Packets + 50 empty Tubes (50ml)250 Transfer Tubes w/o Tubes (50 ml)300 Packets w/o Tubes (50 ml)300 Packets + 300 empty Tubes (50ml)50 Transfer Tubes + 50 Self Standing Tubes (50ml)50 Packets + 50 Self Standing Tubes (50ml)50 Transfer Tubes + 50 empty Tubes (50ml)Packaging50 Transfer Tubes + 50 empty Tubes (50ml)50 Transfer Tubes + 50 empty Tubes (50ml)Packaging50 Transfer Tubes + 50 empty Tubes (50ml)50 Packets + 50 empty Tubes (50ml)Packaging50 Transfer Tubes + 50 empty Tubes (50ml)Packaging50 Transfer Tubes + 50 empty Tubes (50ml)

CodeQ17B14F091Q1B14F091Q5B14F091Q15D14F091Q16E14F091Q18B14F091Q20B14F091Q19B14F091Q17B16N091CodeQ17B14H093Q17B15I093CodeQ17B15E092Q5B15E092CodeQ17B14L095CodeQ17B14H096

Method : EN 15662 d-SPE900 mg MgSO₄, 150 mg PSA900 mg MgSO₄, 150 mg PSA Varian*900 mg MgSO₄, 150 mg PSA, 150 mg C18EC900 mg MgSO₄, 150 mg PSA Varian*, 150 mg C18EC900 mg MgSO₄, 150 mg PSA, 15 mg GCB900 mg MgSO₄, 150 mg PSA Varian*, 15 mg GCB900 mg MgSO₄, 150 mg PSA, 45 mg GCBmide LLE900 mg MgSO₄, 150 mg PSA Varian*, 45 mg GCBMethod : A.O.A.C. 2007.01 d-SPE1200 mg MgSO₄, 400 mg PSA1200 mg MgSO₄, 400 mg PSA Varian*1200 mg MgSO₄, 400 mg PSA, 400 mg C18EC1200 mg MgSO₄, 400 mg PSA Varian*, 400 mg C18EC1200 mg MgSO₄, 400 mg PSA, 400 mg GCB1200 mg MgSO₄, 400 mg PSA Varian*, 400 mg GCB1200 mg MgSO₄, 400 mg PSA, 400 mg C18EC, 400 mg GCB1200 mg MgSO₄, 400 mg PSA Varian*, 400 mg C18EC, 400 mg GCBMethod : C18 d-SPE Tube900 mg MgSO₄, 150 mg C18Method : Mycotoxins d-SPE Tube 900 mg MgSO₄, 300 mg PSAMethod : PSA/C18/GCB dSPE Tube900 mg MgSO₄, 300 mg PSA, 300 mg C18EC, 45 mg GCB

Packaging50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to UsePackaging mg MgSO4, 400 mg PSA50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to Use50 Tubes (15 ml) Ready to UsePackaging50 Tubes (15 ml) Ready to UsePackaging50 Tubes (15 ml) Ready to UsePackaging50 Tubes (15 ml) Ready to Use

CodeQ2A22Z391Q2A22Z891Q2A22C391Q2A22C891Q2A22Z331Q2A22Z831Q2A22Z341Q2A22Z841CodeQ2A23Z592Q2A23Z1092Q2A23D592Q2A23D1092Q2A23Z582Q2A23Z1082Q2A23D582Q2A23D1082CodeQ2A22G094CodeQ2A22Z496CodeQ2A22O447

Page 8: QUICK AND EASY LAB SAMPLE PREP FOR …...is the new brand that identifies the “QuEChERS Products” made in Italy for the extraction and clean up of analytes from a wide variety

Produced by:LAB. INSTRUMENTS S.r.l. - High Pure Standard & Chemicals DivisionTel. +39 080 4969746-9 - Fax: +39 0804969752SS 172 (Putignano-Alberobello) km 28+200 - 70013 Castellana Grotte (BA)Site: www.quelab.it - E-mail: [email protected]

Accreditations and Certifications ISO Guide 34:2009 ISO/IEC 17025:2005UNI EN ISO 14001:2004UNI EN ISO 9001:2008

and are a trademark of Lab.Instruments srl (Italy). All rights reserved. Specifications, term and pricing are subject to change. Not all products is available in all countries. Please consult your local rapresentative to details. QL 01 E 02/15

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