quality control operating procedures for

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APPROVED: QUALITY CONTROL OPERATING PROCEDURES FOR MULTIPLE QUALITY CHARACTERISTICS AND WEIGHTING FACTORS by Peter S. Hsing . Thesis submitted to the Graduate Faculty of the Virginia Polytechnic Institute and State University in partial fulfillment for the degree of DOCTOR OF PHILOSOPHY in Industrial Engineering and Operations Research Dr. Prabhakar M. Ghare, Chairman Dr. Paul E. Torgersen Dr. G. Kemble Bennett Dr. Kenneth E. Case November 1973 Blacksburg, Virginia Dr. B. Harshbarger

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Page 1: QUALITY CONTROL OPERATING PROCEDURES FOR

APPROVED:

QUALITY CONTROL OPERATING PROCEDURES FOR

MULTIPLE QUALITY CHARACTERISTICS AND WEIGHTING FACTORS

by

Peter S. Hsing

. Thesis submitted to the Graduate Faculty of the

Virginia Polytechnic Institute and State University

in partial fulfillment for the degree of

DOCTOR OF PHILOSOPHY

in

Industrial Engineering and Operations Research

Dr. Prabhakar M. Ghare, Chairman

Dr. Paul E. Torgersen Dr. G. Kemble Bennett

Dr. Kenneth E. Case

November 1973

Blacksburg, Virginia

Dr. B. Harshbarger

Page 2: QUALITY CONTROL OPERATING PROCEDURES FOR

ACKNOWLEDGEMENTS

The author is grateful for this opportunity to express his appre-

ciation to the follo~,ing individuals for their help and encouragement

during the completion of this study and the pursuit of his doctorate:

Dr. P. M. Ghare, the author's major advisor, for providing the

initial impetus for research and his invaluable advice and

knowledge during all stages of the study.

The other members of his graduate committee, Dr. G. K. Bennett,

Dr. K. E. Case, Dr. B. Harshbarger and Dr. P. E. Torgersen for their

encouragement, assistance and constructive criticisms.

Mr. Dave Calhoun, Head of the Department of Biostatistics at G. D.

Searle Company for his professional advice and help.,

Mr. E. F. Chace, Mr. A. W. Zeiner and Mr. J. S. Lyday at IBM for

their editorial comment and valuable advice on the organization of the

writing.

The author's parents, Mr. and Mrs. H. T. Hsing, who inspired the

author to work toward the doctorate degree, the author's wife Mina who

sacrificed her own needs in order to help his pursuit of the doctorate

and who offered constant encouragement when it was greatly needed. To these people this dissertation is dedicated.

Mrs. Margie Strickler for her excellent typing of the final draft

of the manuscript.

ii

Page 3: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter

1

2

3

TABLE OF CONTENTS

INTRODUCTION ...

1.1 Multivariate Quality Control Operational Procedure 2

l .2 Importance of Quality Characteristic and Variation in Weights Assigned to Different Characteristics 3

1. 3 Survey of the Literature . . 3

1.4 Overview of the Dissertation . 6

TESTING THE STABILITY OF THE MANUFACTURING PROCESS WITH RESPECT TO DISPERSION .......... .

2.1 Brief Review of the Univariate Case.

8

8

2.2 Notation and Symbols. . . . . 9

2.3 Statistical Test Procedure for Establishing Equivalence of Several Variance-Covariance Matrices. 11

2.4 Establishing the Stability of Past Operation with respect to Dispersion. . . . . . . . . . . . . . . . 12

2.5 Computational Procedure for Testing the Stability of the Manufacturing Process with respect to Dispersion 14

2.6 Computer Program for testing the Stability of Process Dispersion. . . . . . . . . . . . . . . . . 15

2.7 Example of Computations Involved in proving the Stability of the Manufacturing Process with respect to Dispersion. . . . . . . . . . . . . . . . . . . . 16

TESTING THE STABILITY OF THE MANUFACTURING PROCESS WITH RESPECT TO CENTRAL TENDENCY

3.1 Brief Review of Univariate Case.

3.2 Wilks Likelihood Ratio Test ....

3.3 The Critical Value for Decision.

24

24

25

26

3.4 Establishing the Stability of Past Operations with respect to Central Tendency. . . . . . . . . . . . . 27

i i i

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iv

TABLE OF CONTENTS (continued)

Chapter Page

4

5

3.5 Computational Procedure for Testing the Stability of the Manufacturing Process with respect to Central Tendency. . . . . . . . . . . . . 30

3.6 Computer Program for Testing the Stability of Process Central Tendency . . . . . . . . . . . 32

3.7 Example of Computations Involved in proving the Stability of the Manufacturing Process with respect to Central Tendency. . . . . . . . . . . . . . . . . 32

PROCEDURE FOR MONITORING DISPERSION OF THE MANUFACTURING PROCESS ............. . 43

4.1 Brief Review of the Univariate Case. . . . . . 43

4.2 Theorems used in the Development of Dispersion Monitoring Procedure . . . . . . . . . . . . 44

4.3 Statistical Test for the Hypothesis that the Population Variance-Covariance Matrix Equals a Standard Matrix. . . . . . . . . . . . . . . . 45

4.4 Monitoring the Dispersion of the Manufacturing Process 47

4.5 Identification of Characteristics contributing to the Dispersion Control Problem . . . . 48

4.6 Computational Procedure for Monitoring the Dispersion of the Manufacturing Process 51

4.7 Computer Program for Monitoring the Process Dispersion................. 53

4.8 Examples of Computations involved in Monitoring Dispersion of the Current Manufacturing Process. 54

PROCEDURE FOR MONITORING THE CENTRAL TENDENCY OF THE MANUFACTURING PROCESS 59

5.1 Brief Review of the Univariate Case. . . . . . . 59

5.2 Theorems used in the Development of the Central Tendency Monitori no Procedure. . . . . . . . . 60

Page 5: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter

V

TABLE OF CONTENTS (continued)

5.3 Development of the Central Tendency Monitoring Procedure. . . . . . . . . . . . . . . . . . .

5.4 Identification of Characteristics contributing to the Central Tendency Control Problem.

5.5 Computational Procedure for Monitoring the Central Tendency of the Manufacturing Process ....... .

5.6 Computer Program for Monitoring the Process Central Tendency . . . . . . . . . . . . . . . . . . . . . .

5.7 Example of Computations involved in Monitoring

Page

61 61

65

72

75

Central Tendency of the Current Manufacturing Process 76

6 SIMULATION ......... .

6.1 Random Number Generation .

6.2 Pre-analysis of Simulation

6.3 Simulation St11dy with Two Variables.

6.4 Simulation Study with Four Variables .

6.5 Computer Program for Simulation.

7 SUMMARY AND RECOMMENDATION.

7. 1 Summary. . . . . . . .

7.2 Areas for Further Study.

BIBLIOGRAPHY

VITA . . .

Appendix A MAIN PROGRAM FOR TESTING STABILITY OF PROCESS

Appendix B MAIN PROGRAM FOR MONITORING PROCESS ..

Appendix C TWO VARIABLES SIMULATION,MAIN PROGRAM

. . . .

80

80

82

83

86

88

91

91

94

96

99

100

l 06

110

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vi

TABLE OF CONTENTS (continued)

Appendix D FOUR VARIABLES SIMULATION,MAIN PROGRAM ..

Page

115

121

130

131

Appendix E

Appendix F

SUBROUTINES .

TWO VARIABLES SIMULATION,RESULTS ..

(1) Correlation Coefficient= Standard Value

(2) Correlation Coefficient= Standard Value x 0.8 135

(3) Correlation Coefficient= Standard Value x 1.1 139

Appendix G FOUR VARIABLES SIMULATION RESULTS ... 143

(1) Correlation Coefficient= Standard Values and All Variances= Standard Values. . . . . . 144

(2) Correlation Coefficients= Standard Values and All Means= Standard Values. . . . . . . . 148

Page 7: QUALITY CONTROL OPERATING PROCEDURES FOR

LIST OF TABLES

Table Page

I Sample Averages and Sample Variance-Covariance Matrices. 17

II

II I

IV

V

Log10 (Determinant of Si) ............. .

Transformation of W-Statistic to Provide Exact Upper Tail Tests Using F-Distribution.

I

Matrix of Xi Xi ..... . - I -

Matrix of n (!i-K) (!;-!)

V

21

28

33

38

Page 8: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter l

INTRODUCTION

The manufacturing of a product by any successful industrial firm

involves, among many other aspects, an attempt to ensure that the

product meets certain specifications. Originally known as Quality

Control, these attempts were limited to inspection by various methods

and subsequent acceptance or rejection of the item. As the volume of

work grew, sampling techniques were evolved to extend the effectiveness

of the inspections, but, as was soon noted, an improvement in the approach

was required. The search for improvement took the form of attempts to

control processes and avoid the need for a retro-active system, one which

operated after the fact as did quality control. Thi's control effort

became known as Quality Assurance. The names, quality assurance and

quality control, are now used interchangeably in industry.

It is recognized that no system can, in and by itself, assure the

quality of an item. Variations and uncertainties inherent within the

environment are not yet that well understood, predictable, and control-

lable. But within the bounds of the state-of-the-art, quality control as

used herein is meant to convey the idea of in-process techniques that

may be used to control the quality of the finished product.

This research is devoted to the development of a procedure for

manufacturing applications to cases involving items having more than one

quality characteristic. These characteristics are assumed to be measured

on a continuous scale.

1

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2

1.1 Multivariate Quality Control Operational Procedure

Because the preponderance of industrial processes are characterized

by hav1ng more than one parameter requiring control, and because tech-

niques of effectively controlling such as operation are at best under-

developed, the procedures explained in this research should have wide

application throughout industry.

Control charts have been the traditional means by which the need for

action in a given situation was identified. Such charts have not,

however, taken into account the interaction between variables when more

than one parameter is measured. A univariate control chart aids in

determinir,g the stability of the manufacturing process, and action is

taken when the process is not stable. Once the manufacturing process

capabilities have been determined and the process is stable,

action is taken only when the control chart indicates that the process

has gone out of control.

Just as in the case of the univariate quality control charts, the

multivariate situation requires the determination of process

stability with respect to both dispersion and central tendency. After

this stability has been established, the standard values for dispersion

and central tendency may be determined by examination of representative

past data or by consideration of future requirements as expressed by the

management. Stability of the process in the past prognosticates a

continuation of such stability until the occurrence of some assignable

cause that upsets the process. The lack of stability in past operations,

by the same token, would indicate the need for adjustment to the process.

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3

There is no economic advantage, therefore, to be gained from estab-

lishing a monitoring procedure in conjunction with a system that is

not stable.

Once stability of the process has been established and standard

values for dispersion and central tendency calculated, action to main-

tain the process within the established bounds of dispersion and central

tendency becomes management's objective. Maintenance of the process

requires that guidelines for action be stated, e.g., action is required

when sample values indicate a lack of control with respect to dispersion,

central tendency, or both.

l .2 Importance of Quality Characteristic and Variation in Weights Assigned to Different Characteristics

In the multivariate situation, it is likely that the functional or

economic importance of the various characteristics to be controlled will

vary between characteristics. It is therefore desirable that the central

tendency monitoring procedure take into account such variations in

importance. This has been incorporated in the procedure described in

this dissertation and assigning different weights for the central tendency

value both above and below the standard value is presented and explained.

l .3 Survey of the Literature

In 1933, Dr. W. A. Shewhart (33) first proposed the statistical

quality control charts for the univariate case. Further technical and

theoretical developments were carried out by Barnard (2), Duncan (7,8),

Goel, Jain and Wu (10), Hartley (14), Noether (29), Ostle and Steck (30),

Page 11: QUALITY CONTROL OPERATING PROCEDURES FOR

4

Page (31) and Weiler (36,37), etc. In addition to the application of

statistical quality control methods, many of these authors further

developed quality control procedures based on costs and other economic

factors. Because of the need for simultaneous control for related

variables, several authors developed procedures for the joint monitoring

of the central tendencies. Their approaches are briefly described below.

Jackson (15,16) proposed to use Hotelling T-square control chart

for central tendency monitoring. Basically, the test statistic is

where xis the sample average vector,

u is the standard mean vector,

Sis the sample variance-covariance matrix,

k is the number of quality characteristics, and

n is the sample size.

If the computed T-square value exceeds the appropriate upper fractile

of the T-square distribution, then the manufacturing process is said to

lack control.

Ghare and Torgersen (9) proposed to use a Chi-square control chart

for central tendency monitoring. Briefly, the test statistic is

where Vis the variance-covariance matrix. If the computed Q exceeds

the appropriate uoper fractile of the Chi-square distribution with k

degrees of freedom, the manufacturing process is said to lack control.

Page 12: QUALITY CONTROL OPERATING PROCEDURES FOR

5

Montgomery and Klatt (24,25) proposed a method of determining the

optimal sample size, interval between samples, and critical region of the

parameters, based on the T-square control chart. Here the objective

function is the cost per unit of product for the test procedure, i.e.,

E(c) = E[c(l)] + E[c(2)] + E[c(3)]

where E[c(l)] is the expected cost per unit of sampling and carrying out

the test procedure, E[c(2)] is the expected cost per unit associated

wi~h investigating and correcting the process when the test procedure

indicates the process is out of control, and E[c(3)] is the expected

cost per unit associated with producing defective products. The optimal

sample size, interval between samples, and the critical region parameter

are derived by minimizing the expected total cost function.

In addition to the T-square control chart, Montgomery and Wadsworth

(26) present a method for monitoring the dispersion of the manufacturing

process. Basically, it is to convert the variance-covariance matrix

into a univariate random variable, the logarithm of the determinant of

the variance-covariance matrix. The distribution of this random

variable can be approximated by the normal distribution. The construction

of the control chart is based on the assumption that the manufacturing

process has already reached the stable state. Several samples are

taken from the process and the logarithm of the determinant of each

sample variance-covariance matrix is computed. Then, if the mean and the

standard deviation of those logarithms are represented by y and sy,

respectively, the control limits are given by

Page 13: QUALITY CONTROL OPERATING PROCEDURES FOR

6

and

where Za/ 2 is the appropriate percentage point of the nonnal distribution.

The process is said to be out of control with respect to dispersion if

the logarithm of the determinant of the sample variance-covariance

matrix computed from the sample falls outside the control limits.

Otherwise, the process is said to be under control with respect to

dispersion.

1.4 Overview of the Dissertation

A procedure for testing the stability of the manufacturing process

with respect to the dispersion is established in Chapter 2. This

procedure is derived from the multivariate statistical technique for

identifying the common dispersion for multiple populations.

A procedure for testing the stability of the manufacturing process

with respect to the central tendency is developed in Chapter 3. This

procedure is based upon the Wilks Likelihood Ratio test which is

usually used for identifying the common mean for multiple populations.

A procedure for monitoring the uniformity of the products is

presented in Chapter 4. When the manufacturing process is found to be

out of control with respect to dispersion, then a set of follow-up

statistical tests is presented as an aid in identification of those

manufacturing phases which need adjustment.

A procedure for monitoring the central tendency is presented in

Chapter 5. This procedure allows assignment of different weights to

Page 14: QUALITY CONTROL OPERATING PROCEDURES FOR

7

different quality characteristics and also for deviations above and below

the standard values. Here again, when the process is found to be out of

control with respect to the central tendency, a set of statistical tests

is presented to assist in locating the manufacturing phases which need

adjustment.

In Chapter 6, two simulation studies are presented. The purpose of

these simulations is to present alternate methods of examining the way

in which a proposed system will respond to the situation in which the

manufacturing process departs from the standard with respect to the

central tendency and/or the dispersion.

In Chapter 7, a summary of the entire work and some recommendations

for further study are presented.

Page 15: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter 2

TESTING THE STABILITY OF THE MANUFACTURING PROCESS

WITH RESPECT TO DISPERSION

The purpose of this chapter is to develop and present a procedure

for testing the stability of the manufacturing process with respect

to dispersion. The major assumptions regarding the testing procedure

are stated. The mathematical symbols used in this work are defined, and

a step-by-step computational procedure is given for the user's con-

venience. As an illustration, an example with two quality character-

istics is discussed. It should be noted that the same example is used

in all chapters for the sake of consistency and simplicity.

2.1 Brief Review of the Univariate Case

Traditionally to prove the stability of the manufacturing process

in the univariate case, 20 to 40 samples, each containing 4 or 5 items

are taken from the manufacturing process at relatively equal time

intervals. This sample size and number of samples have been considered

satisfactory by many industrial applications. After the measurements

are taken, the central line and the trial limits are computed for one

of the following control charts.

Upper Lower Control Limit Control Limit Central Line

R-Chart D4 [ o3 R R

a-Chart s4 a B3 cr a

8

Page 16: QUALITY CONTROL OPERATING PROCEDURES FOR

9

where o3, o4, s3, and B4 are constants which can be found in most quality

control texts. The R-Chart is easier to use, but is is appropriate only

when the sample size is small.

If all the statistics of the dispersion computed from the samples

fall within the trial limits, then the dispersion of the past operation

is concluded to be in control. If the process capability is satisfactory,

then maintenance of the statistics of the central line becomes manage-

ment's goal and the trial limits become the criteria for monitoring the

future manufacturing process.

2. 2 Notation and Symbols

The following definitions apply to all discussions and explanations

presented herein.

n is the sample size.

k is the number of quality characteristics.

mis the number of subgroups, lots or populations.

xitj is a single measruement where:

i indicates the sequence of time interval or the manufacturing

lot and i = 1, 2, ... , m.

t indicates the quality characteristic and t = 1, 2, ... , k.

j indicates the individual item taken from the ith time

interval and j = l, 2, ... , n.

{xilj xi 2j xikj) are measurements of all k-quality charac-

teristics made on the jth individual item which was taken

during the ith time interval.

Page 17: QUALITY CONTROL OPERATING PROCEDURES FOR

x. ,

10

Xill xil 2 . . xiln

Xi 21 Xi22 x.2 , n = [x; tj] = . . . .

xi kl xik2 . xikn

are measurements of all n individual items which were taken

during the ith time interval.

Ki = (xil x; 2 ... xik) is the sample average vector for the

ith manufacturing lot. I

§_ = (x1 x2 ... xk) is the grand sample average vector.

s. ,

I

Sill Sil 2

Si 21 si22 = [sith] =

Si kl sik2

where sith fort,h=l,2, ... ,k

and i = l, 2, ... , mis the sample variance-covariance matrix

and elements of this matrix are computed from the observations

taken from the ith manufacturing lot.

_!:!_ = (u1 u2 ... uk) is the population mean vector.

v,, v, 2

V 21 v22 V = [vth] =

vkl vk2

Page 18: QUALITY CONTROL OPERATING PROCEDURES FOR

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is the population variance-covariance matrix.

Xis a general notation for a k-variates random variable, such

that l is normally distributed with mean vector equal !Land

variance-covariance matrix equal to V.

2.3 Statistical Test Procedure for Establishing Equivalence of Several Variance-Covariance Matrices

Let there be m populations and the random variable in each

population follows a k-variates normal distribution with a common mean

vector!:!_ and a variance-covariance matrix Vi where i = l, 2, ... , m.

It is assumed that all the Vi have the same value V. Therefore, the

problem may be stated so as to test the null hypothesis:

Ha: v1 = V 2 = = V = V m

against the alternative hypothesis

V. f V · l J

where if j and i, j = l, 2, ... , m.

This testing procedure is given by Kramer and Jensen (21 ), and

Chakravati, Loha and Kay (5). First, a sample of size ni is taken from

the ith population and the estimator of the variance-covariance matrix

for the ith population, Si, is calculated for i = 1, 2, ... , m.

The pooled estimator of the variance-covariance matrix is computed in

the following way:

(n1-l)s1 + (n2-l)s2 + ... + (nm-l)Sm ( n 1 - l ) + ( n 2 - l ) + .. . + ( nm -1 )

Page 19: QUALITY CONTROL OPERATING PROCEDURES FOR

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In practice, it is preferable that all samples be of equal size.

In the case of the equal size, the pooled estimator of the variance-

covariance matrix can be simplified as

s1 + s2 + ... + Sm s =-------p m

The statistic used in testing the null hypothesis is

l l -----]} n .-1 m 1 I (ni-1)

i = 1

m m x{[ 1_I __ 1(ni-l)] x LogjSpl - _I [(ni-l) LogjSij]} (2.1)

1 = l

If all the sample sizes are equal, then

2k2+3k-l m2-l R = 2.3026 [l - 6(k+l )(m-1) x m(n-1 )]

m x [m(n-1) LogjSpl - (n-1 \~1 LogjSi I] (2.2)

When dealing with large samples, the procedure is to reject the null

hypothesis if the test statistic R exceeds the appropriate upper fractile

of the Chi-square distribution with k(k+l)(m-1 )/2 degrees of freedom.

2.4 _Establishin~ the Stability of Past Operation with respect to Dispersion

The products fabricated during each time interval can be considered

as a population and, as there are m time intervals, so there are m

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populations. It is assumed that the random variable in each of the

populations follows a k-variate normal distribution. Furthermore, the

central tendency is assumed to be under control during all the manufac-

turing periods. However, populations formed by the products fabricated

in different time intervals may have different variance-covariance

matrices if the manufacturing process is not stable with respect to the

dispersion. The statistical test just discussed in section 2.3 may be

applied to find out whether the past operations were actually in control

or not. Suppose a sample of size n was taken from each of them time

intervals. Now, m-sample variance-covariance matrices and the pooled

samples variance-covariance matrix are computed as Si where i = 1, 2,

... , m and Sp, respectively. The test statistic R for the equal sample

size can be computed according to equation (2.2). If the test statistic

R does not exceed the appropriate upper fractile of the Chi-square

distribution with k(k+l )(m-1 )/2 degrees of freedom, it may be concluded

that all the variance-covariance matrices are not significantly different

and the stability of dispersion for the manufacturing process has been

achieved. Furthermore, all the samples may be pooled to estimate

the variance-covariance matrix for the manufacturing process. If the

capability of the manufacturing process is satisfactory and a standard

value for dispersion of the process has been determined, maintenance

of the standard variance-covariance matrix becomes management's goal.

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2.5 Computational Procedure for Testing the Stability of the Manufacturing Process with Respect to Dispersion

A sample of size n was taken from each of m manufacturing lots.

There are k measurements made on each of the individual items:

1) Record the measurements for the ith manufacturing lot, Xi,

in the matrix form defined in Section 2.2, where i = l, 2,

•.. ' m.

2) Compute the sample average vector, Ki' for the ith manu-

facturing lot, where i = l, 2, ... , m.

3) Compute the sample variance-covariance matrix, S;, for

the ith manufacturing lot, where i = 1, 2, ... , m.

4) Compute the determinant of the ith sample variance-covariance

matrix, IS; I, where i = 1, 2, ... , m.

5) Compute the pooled sample variance-covariance matrix s1 + s2 + ... + Sm

s = --------p m

6) Compute the determinant of the pooled variance-covariance

matrix, !Sp!•

7) Compute the R-statistic according to equation (2.2).

8) Compute the degrees of freedom for the Chi-square distribution;

d . f . = k ( k + 1 ) ( m-1 ) / 2 .

9) Find the table value of the upper fractile of the Chi-square

distribution with k(k+l )(m-1)/2 degrees of freedom and a

predetermined type one error.

10) Compare the value of the R-statistic in step 7) and the table

value of Chi-square distribution in step 9). The

Page 22: QUALITY CONTROL OPERATING PROCEDURES FOR

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manufacturing process is stable if the value in step 7) is

less than or equal to the value in step 9). The manufac-

turing process has not achieved the stable state with respect

to dispersion if the value in step 7) is greater than the

value in step 9).

2.6 Computer Program for Testing the Stability of Process Dispersion

1) Input Variables

IR= sample size

2)

JC= number of quality characteristics per inspected item

M = number of lots inspected

x(I,J,L) = measurement of the Lth quality characteristic on

the Jth item in the Ith inspected lot where

L = 1, 2,

J=l,2,

... ,

... ' JC;

IR;

I = 1, 2, ..• , M.

TABLEV = Chi-square table value with degree of freedom equal to

(M-1 )JC(JC+l )/2

Input Format

Variables

IR' JC, M

TABLEV

DO I = 1 ' M

DO J = 1 ' IR

(x(I,J,L), L = 1, JC)

Format

(315)

(Fl0.4)

(8Fl0.4)

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3) FORTRAN Listing of Main Program

See Appendix A.

2.7 Example of Computations Involved in Proving the Stability of the Manufacturing Process with respect to Dispersion

ABC Company manufactures an antidiarrheal tablet preparation con-

taining two active drug ingredients, A and B. The major ingredient,

A, has the antidiarrheal effect exclusively. Component Bis present

in the tablet to prevent the side effects. It does not contribute

to the antidiarrheal activity, but produces an unpleasant physiological

effect when more than the recommended number of tablets are consumed.

The rest of the tablet contains a neutral ingredient. The Food and Drug

Administration has specified a range for each ingredient and a penalty

to be imposed for each detected violation of the specification.

Therefore, it ·is necessary to control both ingredients, A and B. This

example will be used throughout this whole research for illustrative

purposes.

In order to prove the stability of the manufacturing process, 30

samples of 20-tablets each are taken ar relatively equal time intervals.

Each tablet is assayed for both components A and B. The sample averages

and sample variance-covariance matrices are then calculated and

recorded in the manner shown in Table I.

Page 24: QUALITY CONTROL OPERATING PROCEDURES FOR

17

Table I

Sample Averages and Sample Variance-Covariance Matrices

x, = (249.5301 2.5184) S = [ 16.0526 0.5403] l 0.5403 0.0287

x = (250.6852 2. 5084) S = [ 19.6316 0.6244] 2 0.6244 0.0275

x = (248.6164 2. 4587) [ 9. 9474 0. 3583} -3 s = 3 0. 3583 0. 0198

x = (250.4709 2.5004) [ 19. 3158 0.5654] s = 4 0.5654 0.0218

x = (250.1059 2.4902) [ l 0. 6842 0.2570] -'..:5 S5 = 0.2570 0.0163

x = (250.4703 2.5066) [ 8.8421 0.2763] s6 =

0.2763 0.0132

x = (251.5789 2.5817) [ 8.8947 0.3228] -7 S7 = 0.3228 0.0184

x = ( 248. 1619 2.4193) [10.4737 0. 3481] .'.'.8 s = 8 0.3481 0.0185

x = (250.9381 2.5403) [14.0526 0.4426] s = 9 0.4426 0.0193

Page 25: QUALITY CONTROL OPERATING PROCEDURES FOR

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X10 = (250.8936 2.5369) S = [12.5263 o. 5021] lO 0.5021 0.0280

K,, = (249.7131 2.4697) = [17 .8947 0.5718] s,, 0.5718 0.0268

K12 = (249. 3701 2.5057) S = [1 o. 9474 0.3366] 12 0.3366 0.0160

X13 = (251.7016 2.5592) S = [ 13. 7895 o. 5066] 13 0.5066 o. 0242

!14 = (250.0506 2.5048) S = [ 13.4737 0.4056] 14 0.4056 0.0209

!15 = (250.3838 2.5304) S = [13.6842 0.4751] 15 0.4751 0.0247

K16 = (247. 0457 2.4733) S = [14 .4211 0. 5313] 16 0.5313 0.0291

!17 = (249.6074 2.4751) S = [14.1053 o. 5136] 17 0.5313 o. 0291

K18 = (249.8517 2.5093) S = [13.5263 0.4001] 18 0. 4001 0.0208

x 9 = (250. 1998 2.5091) S = [10.2105 o. 2995] -1 19 0.2995 0.0154

Page 26: QUALITY CONTROL OPERATING PROCEDURES FOR

19

K20 = (249.5176 2.4525) S = [13. 2105 0.3651] 20 0.3651 0.0172

K21 = (249.2402 2.4948) = [15.4737 0. 5222] s21

0.5222 0.0233

K22 = (249. 6689 2.4789) [ 9. 4737 0. 3045] s -22 - o. 3045 o. 0138

!23 = (251.7006 2.5601) S = [21. 7368 0.6605] 23 0.6605 0.0248

!24 = (251.3898 2.4929) 524 = [

8.3684 0.2876]

0.2876 0.0202

!25 = (250. 7766 2.4819) S = [ 10. 5789 0.2819] 25 0.2819 0.0178

K26 = (250. 1666 2.5082) S = [ 23. 8421 0.7177] 26 0.7177 0.0265

K27 = (250.3498 2.5125) S = [ 10.0526 0. 2911] 27 0.2911 0.0174

x28 = (250.4281 2.5148) [ 8.8421 0.2541] s -28 - 0. 2541 0.0139

K29 = (249.8111 2.4978) S =[13.8947 0.4147] 29 0.4147 0. 0189

!30 = (250.6680 2.4936) S = [15.8421 0.5249] 30 0.5249 0.0261

Page 27: QUALITY CONTROL OPERATING PROCEDURES FOR

20

All the determinants and the logarithms of determinants are

calculated and recorded in the manner shown in Table II.

According to equation (2.2)

8 + 6 - l 899 R = 2.3026 X [l - (l 8)( 29 ) X ( 30)( 29 )]

X [(30)(19)(-0.9927) - (19)(-31.0448)]

= 2.3026 X 0.9743 X 34.01222 = 53.8690

Page 28: QUALITY CONTROL OPERATING PROCEDURES FOR

i

l

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

21

Table II

Log10 (Determinant of Si)

Determinant of Si logl 0 (Determinant of Si)

0.1683 -0. 7739

0.1507 -0.8227

0.0690 -1.1611

0.1023 -0.9101

0. l 077 -0.9678

0. 0400 -1.3971

0.0599 -1. 2285

0.0726 -1 . 1391

0.0753 -1 . 1232

0.0982 -1. 0079

0.1527 -0.0162

0.0623 -1.2055

0.0777 -1 . 11 35

0. 1166 -0. 7799

o. 1117 -0.9516

0.1376 -0.8614

0. 1392 -0.8564

0.1218 -0.9143

0.0677 -1. 1694

0.0936 -1. 0207

0. 0885 -1 . 0531

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22

22 0.0383 -1.4168

23 0. 1037 -0.9942

24 0.0860 -1.0655

25 0. 1089 -0.9598

26 o. 1172 -0.9311

27 0.0903 - 1. 0443

28 0.0582 -1.2351

29 o. 0901 -1.0453

30 0.1383 -0.8595

Page 30: QUALITY CONTROL OPERATING PROCEDURES FOR

23

If the predetermined level of significance is one percent, then

x2 [ ( k ) ( k + 1 )( m- 1 ) / 2 , 0 . 9 9] = x2 ( 8 7 , 0 • 9 9 ) = 11 3 •

The test statistic R does not exceed the appropriate upper fractile

of the Chi-square distribution with k(k-l)(m-1)/2 degrees of freedom,

and the null hypothesis is therefore accepted. In other words, since

the products manufactured in different time intervals have the same

dispersion, it may be concluded that stability of the manufacturing

process has been achieved. Since the manufacturing p~ocess capability

is satisfactory, a decision to use

r 113.4596 ! , 0.4301 i

o. 43oil I 0.0213:

as the standard value of the variance-covariance matrix is made, and

maintaining

-ll3.4596

0. 4301

o. 43011 o. 0213j

as the process dispersion matrix becomes management's goal.

Page 31: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter 3

TESTING THE STABILITY OF THE MANUFACTURING PROCESS

WITH RESPECT TO CENTRAL TENDENCY

The purpose of this chapter is to establish a procedure for testing

the stability of the manufacturing process with respect to the central

tendency. The major assumptions regarding the testing procedure are

stated and a step-by-step computational procedure is given for the

user's convenience. The example used in the last chapter is carried

over for illustrative purposes.

3.1 Brief Review of Univariate Case

Traditionally to prove the stability of the manufacturing process

in the univariate case, 20 to 40 samples, each containing 4 or 5 items are

taken from the manufacturing process at relatively equal time intervals,

as in the case of proving the stability of dispersion. The central line

is m

X = I xi i = l

and the trial limits are

x - A2R and x + A2R where A2 is a constant which can be found in most statistical quality

control texts. If all the sample means fall within the trial limits,

then the mean of the manufacturing process is concluded to be in control.

If management is satisfied with the capability of the manufacturing

process, then maintenance of the central line becomes management's goal

24

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25

and the trial limits become the criteria for monitoring the future manu-

facturing processes.

3.2 Wilks Likelihood Ratio Test

The likelihood ratio test was originally developed by Wilks (38)

and discussed in detail by Anderson (1) and Kramer and Jensen (20).

Let there be m multivariate populations, such that the random variable

(xil xi 2 ... xik) from each population is normally distributed with mean

vector .!:!_i and a common variance-covariance matrix V, where i = 1, 2, ... ,

m. It is desired to test the null hypothesis

against the alternative hypothesis

H1: U. I U. -1 -J

where i; j, and i, j = l, 2, ... , m.

First of all, a sample of size n is randomly selected from each

population and k measurements are taken for each item. The measurements

of all the inspected items from the ith population can be written in I

the matrix form as Xi as defined in section 2.2, where i = 1, 2, ... ,

m. The sample average vector for the ith population and the grand

average vector can be computed as Ki and§_ respectively, where i = l,

2, ... , m. Now T, a (kxk) matrix, is defined as the 11 sum of square of

total , 11 and can be computed in the followinq wa.v:

m T = l

i=l

I x. x. l l

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26

A, a (kxk) matrix, is defined as the "sum of square of among-group," and

can be computed in the following way:

I m A = n l

i=l (X.-G) (X.-G} -, - -, -

and E, a (kxk) matrix, is defined as the "sum of square of within-group,"

and can be computed in the following way:

E=T-A.

Finally, the Wilks Likelihood Ratio test is defined as

The distribution of the test statistic W depends upon the parameters of

k (the number of the measurements per inspected item), va (degrees of

freedom among-group= m - 1), and ve (degrees of freedom within-group=

m x n - m). The null hypothesis

is to be rejected for the small value of the computed W-statistic.

3.3 The Critical Value for Decision

The distribution of the test statistic W depends upon the parameters

of k, va, ve. Kramer and Jensen (20) have prepared a simple table for

type one error equal to 0.05 and 0.01 where k ranges from 1 to 5, where

va takes on values up to 6, and where ve assumes values between 2 and

1000 inclusive. Wall (35) has prepared a table for type one error

equal to 0.05 and 0.01 where k ranges from l to 8, where va takes on

several values between land 120, and where ve assumes values between

Page 34: QUALITY CONTROL OPERATING PROCEDURES FOR

27

1 and 1000 inclusive. When values of k and va fall outside the ranges

covered in the available tables, Kramer and Jensen (20) presented some

alternatives. One of the alternatives requires a transformation of the

computed value of W-statistic and is shown in Table III.

When values of k and va are as in the first column, then the trans-

formation indicated in the second column generates a quantity having an

F-distribution with degrees of freedom as listed in the third column.

The null hypothesis

is rejected when the transformed value of W-statistic exceeds the upper

fractile of the F-distribution with degrees of freedom listed in the

corresponding third column and the predetermined type one error.

Other alternatives should be used when the values of k and va are other

than those in Table 1. An approximation for large samples can be used

as follows. Let

b = ve _ (k-va+l) 2

the hypothesis in question is rejected if-bx LnW exceeds the upper

fractile of Cni-square distribution with (k x va) degrees of freedom.

3.4 Establishing the Stability of Past Operations with respect to Central Tendency

The products fabricated during each time interval can be considered

as a population and, as there are m time intervals, so, there are m

populations. It is assumed that the random variable in each of the

populations follows a k-variate normal distribution. Furthermore, the

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28

TABLE II I

Transformation of W-Statistic to Provide Exact Upper Tail Tests Using F-Distribution

Parameters (k,va) Statistic havinq F-dist. Deqrees of Freedom

va = 1, any k 1 - w ve + va - k W X k k, (ve+va-k)

va = 2, any k 1 - /W ve + va - k - 1 X k /W 2k, 2(ve+va-k-1)

k = 1, any va 1 - W ve W X va va, ve

k = 2, any va 1 - 1W ve -X /W va 1 2va, 2(ve-1)

Page 36: QUALITY CONTROL OPERATING PROCEDURES FOR

29

process dispersion is assumed to be in control in all the manufacruring

periods. Populations formed by the products fabricated in different

time intervals may have different central tendency if the manufacturing

process is not stable with respect to the central tendency. Wilks

Likelihood Ratio test just discussed in section 3.3 may be applied to

find out whether the past operations were actually in control or not.

Suppose a sample of size n was taken from each of them time intervals.

Now, m-sample average vectors and the grand sample average vector can be

computed as Ki where i = 1, 2, ... , m and §_ respectively. The "sum of

square of tota 1 , 11

m T = l

i = 1

I

X. X. , the "sum of square of among-group, 11 l l

m I

A= I n(Ki-§_) (!-§.), the "sum of square within-group," i = 1

E = T - A, and Wilks Likelihood Ratio test statistic,

w = ffi can be calculated. If the test statistic Wis less than the corresponding

critical value with the parameters k, va and ve, then, the

conclusion is that the past operations were not stable. Otherwise,

the past operations were stable and one may expect the stability to

continue. At this time, the capability of the manufacturing process has

been proved satisfactory; a standard value for the central tendency has

been determined; and maintenance of this standard value becomes manage-

ment's new goal.

Page 37: QUALITY CONTROL OPERATING PROCEDURES FOR

30

3.5 Computational Procedure for Testing the Stability of the Manufacturing Process with Respect to Central Tendency

A sample of size n was taken from each of m manufacturing lots.

There are k measurements made on each of the individual items. Note

that all the samples were the same as those used in the last chapter.

1) Record measurements for the ith manufacturing lot, X;,

in the matrix form defined in section 2.2, where i = 1,

2, ... , m.

2) Perform the matrix multiplication for the ith manufacturing

lot, X; X;, where i = 1, 2, ... , m.

3) Compute the "sum of square of total" matrix, I I I

T = x1 x1 + X2 x2 + ... + Xm Xm

4) Compute the determinant of the II sum of square of tota 1"

matrix, !Tl. 5) Compute the sample average vector,!;• for the manufacturing

lot, where i = 1, 2, ... , m.

6) Compute the grand sample average vector,§_.

7) Perform the matrix multiplication for the ith manufacturing I

lot, (!;-§.) CK;-§.), where i = 1, 2, ... , m.

8) Compute the "sum of square of among-group" matrix, I I I

A= n[(!1-§_) ([1-§_)+(~-§_) (~-§_)+ ... +(~-§_) (~-§_)]

9) Compute the determinant of the "sum of square of group"

matrix, !Al. 10) Compute the "sum of square of within-group" matrix,

E = T - A.

Page 38: QUALITY CONTROL OPERATING PROCEDURES FOR

31

11) Compute the determinant of the "sum of square of within-

group" matrix, jEj.

12) Compute the test statistic,

w =

13) Compute values of parameters, va = m - l and ve = m(n-1).

14) Find the table value of W-statistic indexed by parameters,

k, va, and ve from Kramer and Jensen (20) or Wall (35). The

manufacturing process is said to be stable with respect to

central tendency if the W-statistic exceeds the table value.

Otherwise, the process is concluded not to be stable.

15) If the table value for the W-statistic indexed by param-

eters k, va, and ve is not available:

a) Convert the W-statistic into an F-statistic according

to the transformation given in Table I and compare it

with the appropriate upper fractile of F-distribution.

The process is said to be not stable if the converted

F-statistic exceeds the table value. Otherwise, the

process is concluded to be stable.

b) If Table I cannot be applied, then compute

Z = -[ve - (k-va+l)/2](LnW) .

The manufacturing process is said to be not stable if

the Z value exceeds the upper fractile of Chi-square

distribution indexed by k(va) degrees of freedom and a

predetermined type one error. Otherwise, the process

is concluded to be stable.

Page 39: QUALITY CONTROL OPERATING PROCEDURES FOR

32

3.6 Computer Program for Testing the Stability of Process Central Tendency

This computer program is combined with the computer program for

Testing the Stability of Process Dispersion described in section 2.6;

therefore, there is no need to duplicate those variables already

inputed in the last computer program.

1) Input Variables

VA= Degrees of freedom among-group= m - 1

VE= Degrees of freedom within-group= m(n-1)

INDEX= 1 indicates table value is available,

= 2 indicates F-transformation,

= 3 indicates Chi-square transformation.,

TABLEM = Table value according to the given index number.

2) Input Format

Variables

VA, VE

INDEX, TA BLEM

Format

(2Fl0.4)

(15, Fl0.4)

3) Fortran Listing of Main Program

See Appendix A.

3.7 Example of Computations Involved in Proving the Stability of the Manufacturing Process with Respect to Central Tendency

The example in section 2.7 is carried over for discussing the test

of the stability of the manufacturing process with respect to central

tendency. From the same 30 samples of 20-tablet size used in the

Page 40: QUALITY CONTROL OPERATING PROCEDURES FOR

33

I I I

last example, Xi Xi' n(Xi -X) (Xi-X), where i = 1, 2, ... , m, T

matrix, A matrix and E matrix are calculated and recorded as shown in

Table IV.

The 11 sum of square of total 11

30 I

T = I x. x. = i =l l l

[37,558,460.0000

375,919.8000

375 '919 .8000·1

3,770.9130 .....J

and the determinant of T = 315,621,300.0000. The 11 sum of square among-

group 11

and the determinant of A= 0.9502.

r 431.1323

13. 2196

7 13. 2196 I !

0. 6410 !

Therefore, the 11 sum of square within-group 11 is

[37,558,460.0000 375,906.500071

E=T-A= 375,906.5000 3,770.2720 I

and the determinant of Eis 299,892,7000.0220.

Hence, the test statistic

W = 299,892,700.0220/315,621 ,300.2730 = 0.9501 .

Here, k = 2, va = 29, ve = 570 and F-transformation is applied to this

case. The degrees of freedom of converted F-statistic are (2va, 2ve-2)

= (58, 1138), and the converted F-statistic is calculated in the

fo 11 owing way:

F = l - 0.9747 570 - 1 0.9747 X 29 = 0.050l '

Page 41: QUALITY CONTROL OPERATING PROCEDURES FOR

34

Suppose the type one error is one percent, then the 99 percent upper

fractile of. the F-distribution with degrees of freedom (58, 1138) is

1.48. Since 0.0501 is less than 1.48, the null hypothesis is accepted

and the past operations are said to be in control.

Page 42: QUALITY CONTROL OPERATING PROCEDURES FOR

35

Table IV

I

Matri X of X; X;

i -

1 [ 1 , 245,609.0000 12,578.7900]

12,578.7900 127.3955

2 [ 1 ,257 ,233. 0000 12,588.2600]

12,588. 2600 126.365~

3 [1 , 236,390.0000 12,232.2500]

12,232.2500 121.2809

4 [1,255,079.0000 12,536.3700]

12,536.3700 125.4569

5 [ 1 ,251 ,261. 0000 12,461 . 0300]

12,461.0300 124.3288

6 [1,254,875.0000 12,561.7000]

12,561.7000 125.9085

7 [1,266,007.0000 1 2 , 996. 3500]

12,996.3500 133. 6581

8 [ 1 , 231 ,885. 0000 12 , 041 • 01 00]

12,014.0100 117 .4087

Page 43: QUALITY CONTROL OPERATING PROCEDURES FOR

36

i

9· [ 1 ,259 ,665. 0000 12,757.4300]

12,757.4300 129.4265

10 [1,259,189.0000 12 , 719 . 11 00 ]

12,719.1100 128 ,8392

11 [ 1 ,247. 472. 0000 12,344.9400]

1 2 , 344 . 94 00 122.4927

12 [1,243,916.0000 1 2 • 503 . 5100 l 12,503.5100 125.8793_

13 [ 1 ,267. 334. 0000 1 2 , 892 . 9200 ]

12,892. 9200 131. 4551

14 [1,250,761.0000 1 2 , 534 . 0800]

12, 34. 0800 125.8737

15 [1,254,100.0000 12,680.5800]

12,680.5800 128.5299

16 [ 1,240,749.0000 12,329.5300]

12,329.5300 122. 9004

17 [1,246,344.0000 12 , 365. 7 300 ]

12,365.7300 123.0636

18 [1,248,774.0000 12 , 546. 6400 ]

12,546.6400 126.3273

Page 44: QUALITY CONTROL OPERATING PROCEDURES FOR

37

i -

19 [1,252,192.0000 12,561.1000]

12,561.1000 126.2023

20 [1 , 245,431.0000 12,245.9700]

12,245.9700 120. 6255

21 [1,242,707.0000 12,445.9600]

12,445.9600 124.9233

22 [ 1 , 246,871 . 0000 12,384.0700]

12,384.0700 123.1657

23 [1,267,476.0000 1 2 , 900 . 1 000]

12,900.1000 l 31 . 5538

24 [1,264.095.0000 12,539.1000]

12,559.1000 124.6713

25 [ 1 ,257, 978. 0000 12,453.2300]

12,453.2300 123.5317

26 [1,252,119.0000 12,562.9900]

12,562.9900 126. 3254

27 [1,253,691.0000 12,585.5100]

12,585.5100 126.5823

28 [1,254,452.0000 12,600 .4400J

12,600.4400 126.7500

Page 45: QUALITY CONTROL OPERATING PROCEDURES FOR

38

; -

29 [ 1 ,248. 376. 0000 1 2 , 48 7 . 51 00]

12,487.5100 125. 1400

30 [1,256,989.0000 12,511.2100]

l 2,511 . 21 00 124. 8558

Page 46: QUALITY CONTROL OPERATING PROCEDURES FOR

39

Table V

- I

Matrix of n{!;-!) {!;-!)

; -

1 [ 8.5186 -0. 1735]

-0.1735 0.0035

2 [ 5.0489 0. 0326]

0.0328 0.0002

3 [ 49.0668 1.4550] 1. 4550 0. 0431

4 [ 1 ,6609 -0,0272]

-0.0272 0.0004

5 [ 0.1181 0.0230] 0.0230 0.0045

6 [ 1. 6542 0.0082] 0.0082 0.0001

7 [ 38.9872 2. 1388] 2. 1388 0. 1173

8 [81.6725 3.4707]

3.4707 0. 1475

9 [11.4117 0.5307]

0.5307 0.0247

Page 47: QUALITY CONTROL OPERATING PROCEDURES FOR

40

; -

10 [ 10.1060 0.3941]

0.3941 0.0154

11 [ 4.4111 0.3334] 0.3334 0.0252

12 [13.2061 -0.0097]

-0.0097 0. 0001

13 [46. 1378 1 .6433] l . 6433 0.0585

14 [ 0. 3491 0.0010] 0.0010 0. 0001

15 [ 0.8087 0.1017] 0. l 017 0.0126

16 [25.8558 0.7235] 0.7235 0.0202

17 [ 6.6191 0. 3459] 0.3459 0.0181

18 [ 2.1907 -0.0275]

-0.0275 0.0003

19 [ 0.0058 0.0013]

o. 0013 0.0003

Page 48: QUALITY CONTROL OPERATING PROCEDURES FOR

41

i -

20 [ 8.8480 0.6998] 0.6998 0.0553

21 [17.7652 0.1951] 0. 1951 0. 0021

22 [ 5.2791 0.26931 0.2693 0.0137

23 [46.0784 1. 6682] l. 6682 0.0604

24 [29.1429 -0.2963] -0. 2963 0.0030

25 [ 7.0530 -0.2764] -0.2764 0. 0108

26 [ 0. 0052 -0.0010] -0.0010 0.0002

27 [ o. 5583 0. 0245] 0.0245 0.0011

28 [ 1. 2045 0.0475] 0.0475 0.0019

Page 49: QUALITY CONTROL OPERATING PROCEDURES FOR

42

i -

29 [ 2.7615 0.0545 ]

0.0545 0.0019

30 [ 4. 7095 -0.1122 J -0. 1122 0.0027

Page 50: QUALITY CONTROL OPERATING PROCEDURES FOR

Chapter 4

PROCEDURE FOR MONITORING DISPERSION

OF THE MANUFACTURING PROCESS

The purpose of this chapter is to develop an operational procedure

for monitoring the current manufacturing process with respect to the

dispersion. When the manufacturing process is out of control, a set of

statistical tests can be used to locate the manufacturing phases which

need to be adjusted. A step-by-step computational procedure is included

for the user's convenience. The example discussed in previous chapters

is carried over for illustrative purposes.

4.1 Brief Review of the Univariate Case

In the univariate case, either the R-control or the a-chart is

usually employed for monitoring dispersion of the manufacturing process,

and control limits are as follows:

R-chart

a-chart

Upper Control Limit

o4R

B4;-

Lower Control Limit

If the statistic of the dispersion computed from the samples falls out-

side of the control limits, then it is said that the manufacturing

process lacks control and it becomes necessary to search for the

assignable cause. If, on the other hand, the statistic of the dis-

persion falls within the control limits, it is more economical to leave

the manufacturing process alone. However, there are exceptions,

43

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44

sometimes, the manufacturing process is said to lack control even though

the computed statistic of dispersion falls within the control limits,

i.e., seven points in a row fall at one side of the central line. A

more detailed discussion is given by Duncan (6) and Grant (11).

4.2 Theorems Used in the Development of the Dispersion Monitoring Procedure

The following are some theorems used in the development of the

dispersion monitoring procedure. These theorems are either stated or

proved by Stein (34).

Theorem 4-1

If the matrix Bis (kxk), then the determinant .of Bis

where the symbol l denotes the summation of k! terms. (j )

Theorem 4-2

If matrices A (kxk) and B (kxk) are of order k, then the deter-

minant of AB equals (determinant of A) x (determinant of B).

Theorem 4-3

If the matrix A has an inverse, then the determinant of A-l equals

(determinant of A)-l.

Page 52: QUALITY CONTROL OPERATING PROCEDURES FOR

45

Theorem 4-4

Suppose a matrix A (kxk) equals a matrix nB, where n is a constant

and Bis a (kxk) matrix. Then the determinant of A equals (nk x

determinant of B).

Theorem 4-5

If matrix Bis (kxk) then the trace of Bis

k tr(B) = l b ...

i =l 11

Theorem 4-6

Suppose that matrix A (kxk) equals matrix nB, where n is a constant

and B is a (kxk) matrix. Then

tr(A) = n tr(B)

4.3 Statistical Test for the Hypothesis that the Population Variance-Covariance Matrix Equals a Given Matrix

Suppose that a sample of size n with k measurements made on each

individual item is taken from a k-variates normal distribution with

mean vector !1._ and the sample variance-covariance matrix is E. The

likelihood ratio criterion for testing the null hypothesis

H0: E = V

against the alternative hypothesis

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46

is e kn/2 1 n/2 -1/2 tr(nsv-l)

A = ( n) I nSV- I e

The above test procedure was given by Anderson (l ).

Expansion of the likelihood function by Theorem (4-2), Theorem

(4-4) and Theorem (4-6), results in

by Theorem (4-3). The above equation can be simplified as

Taking the logarithm of equation (4.3), results in

Ln >. = kn/2 + f LnlSI - f LnlVI - f tr(SV-l)

(4. 1)

(4. 2)

(4.3)

( 4 .4)

Multiplying (-2) by equation (4.4) generates the likelihood function

L = 2Ln >.=-kn - nLnlSI + nLnjVI + ntr(sv-l)

or

L = n{Ln ffi -k + tr(sv-1 )} (4. 5)

The test statistic Lis asymptotically Chi-square distributed with

degrees of freedom k(k+l )/2 when n becomes large. This test statistic

L was investigated by Box (4), Lawlty (23), Kullback (3) and Korin (17)

etc., and all the investigations show that the approximation appears to

be very good.

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47

4.4 Monitoring the Dispersion of the Manufacturing Process

Suppose the manufacturing process is proved to be stable and the

products fabricated by this manufacturing process follow a k-variate

normal distribution with the standard mean vector U and the standard

variance-covariance matrix V. It is further assumed that the products

fabricated by the current manufacturing process follow the k-variate

normal distribution with the mean vector U and some variance-covariance

matrix E. If the variance-covariance matrix Eis not significantly

different from the standard variance-covariance matrix V, then it may be

concluded that the current manufacturing process is in control. In

order to determine whether the matrix E equals the matrix V, the

statistical technique may be employed to test the n~ll hypothesis

against the alternative hypothesis

The actual operating procedure is to take a sample of size n from the

current manufacturing process, then compute the estimator, S, for the

current process variance-covariance matrix, E. Because the standard

variance-covariance matrix Vis predetermined and the inverse of the

matrix V can be calculated long before the monitoring, therefore, the

statistic, L, is computed as follows:

V -1 L = n {Ln - 5- - k + tr(SV )}

The null hypothesis is rejected if the test statistic, L,exceeds

the appropriate fractile of Chi-square distribution with degrees of

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48

freedom k(k+l)/2. In this case, the conclusion is that the current

manufacturing process lacks control and it becomes necessary to

determine the assignable cause. On the other hand, when the test

statistic, L, does not exceed the appropriate upper fractile of the

Chi-square distribution with degrees of freedom k(k+l)/2, then it is

more economical to leave the manufacturing process alone.

4.5 Identification of Characteristics Contributing to the Dispersion Control Problem

Since there are k quality characteristics to be monitored, and

since the sample results indicate that the current manufacturing process

lacks control, it is then helpful to have some test to identify which

of these k quality characteristics contributes to the lack of control

in dispersion. With this kind of information, efforts can be concen-

trated in those areas which were suspected from the statistical test

results. This enables detection of the trouble spots in relatively

short time. Essentially, the statistical test helps to reduce the

manufacturing process downtime.

For the univariate case, the statistical procedure for determining

the variance of a population, a2, from a given value, a02, is to test

the null hypothesis

against the alternative hypothesis

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49

The procedure for this statistical test is to take a sample of size n

from the population and calculate the estimator of the population

variance, say s2, and the test statistic is computed as

The null hypothesis is rejected if the computed value of C exceeds the

appropriate upper fractile of the Chi-square distribution with degrees

of freedom (n-1 ). The above statistical test is given by Duncan (6).

Suppose there are k quality characteristics to be monitored, so k

populations, each with a variance ejj is assumed. Further assume a

desirable value for the variance of each population, say vjj' where

jj = 1, 2, ... , k. To determine whether the value df ejj is equal to

the value vjj is to test the null hypothesis

against the alternative hypothesis

e · • f V • • JJ JJ

where jj = 1, 2, ... , k.

This is accomplished by taking a sample of size n from the jth

population, computing the estimator of the variance, Sjj' and calculating

the test statistic, Cj, as follows:

(n-1 )Sjj C • = ---.-,,...---=-=--J V .•

JJ (4. 1)

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50

where j = 1, 2, ... , k. The null hypothesis is rejected if the test

statistic falls in the reject region of the Chi-square distribution with

degrees of freedom (n-1 ). In this case, the conclusion is

that the manufacturing phase responsible for the jth quality charac-

teristic is out of control and some adjustment of this characteristic

may be necessary.

Second, the interaction between two quality characteristics is

investigated. The approach taken here is to partition the standard

variance-covariance matrix, the current process variance-covariance

matrix and the sample variance-covariance matrix as follows:

[V, V ij] V = 11 sub V .. V .. Jl JJ

Esub = [ ei; eij] e .. e .. Jl JJ

[5" •;j] 11 Ssub = s .. s .. Jl JJ

where i t j and i, j = 1 , 2, ... , k.

An interest in only two quality characteristics is assumed for each

test and the likelihood ratio approximation test discussed in Section 4.3

is used to test whether the (2x2) population variance-covariance matrix

Esub equals the predetermined variance-covariance matrix, Vsub' The

test statistic, Lsub' can be calculated as follows:

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If the test statistic, Lsub' exceeds the appropriate upper fractile of

the Chi-square distribution with degrees of freedom 2(2+1 )/2 = 3, the

practical conclusion is that Esub does not equal Vsub· Now, suppose

that all the variances in the set of "sub" are proved not siginficatnly

different from their corresponding predetermined variances by previous

Chi-square tests. It is then logical to say that the interaction between

these quality characteristics in the set of "sub 11 is the cause disturbing

the manufacturing process. The total number of this kind of "sub"

statistical tests is

4.6 Computational Procedure for Monitoring Dispersion of the Manufacturing Process

The standard values for the central tendency,!!_, and the variance-

covariance matrix, V, are either computed from the past data or deter-

mined by management. The inverse and the determinant of V can be com-

puted before monitoring the process. Assume the tyoe one error is also predetermined.

A sample of size n is taken from the current manufacturing process

and there are k measurements made on each of then individual items.

1) Compute the sample variance-covariance matrix S based

on the sample measurements.

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2) Perform the matrix multiplication, (sv-l ). -1 3) Compute the trace of SV .

4) Compute the determinant of the sample variance-covariance.

5) Compute the Ln(IVI/ISI),

6) Compute L = n[Ln(IVI/ISI) - k + tr(sv-l )].

7) Find the Chi-square table value indexed by k(k+l )/2 degrees

of freedom and the predetermined type one error.

8) The current manufacturing process is said to be out of

control with respect to the dispersion if the computed value

of Lin step 6) exceeds the Chi-square table value in step

7). Otherwise, leave the process alone.

If the current manufacturing process is out of.control

with respect to the dispersion, then the following statistical test can

be used to assist in locating the trouble spot.

9) Compute the test statistic for the jth population, Cj'

according to equation (4.1) for j = 1, 2, ... , k.

10) If the test statistic Cj exceeds the Chi-square table value

indexed by degrees of freedom (n-1) and the predetermined

type one error, then the manufacturing phase corresponding

to the jth quality characteristic is said to be out of control

and requires adjustment. Here, j = 1, 2, ... , k.

11) Partition the standard variance-covariance matrix, V, and

the sample variance-covariance matrix, S, into (2x2) sub-

matrices. There are k{k-1 )/2 ways to partition matrices

V and S.

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53

12) Compute

Lsub = n {Ln(IVsubl/lSsubl) - 2 + tr(Ssubvsub-l)}

The total number of these sub-tests equals k(k-l)/2.

13) If the variances in the set of 11 sub 11 were proved not signi-

ficantly different from their corresponding standard variances

by Chi-square tests defined in step 9), but if the Lsub

exceeds the Chi-square table value indexed by degrees of

freedom 3 and the predetermined type one error, then it is

concluded that the interaction between the two quality

characteristics in the set of 11 sub 11 is the cause of troub 1 e.

4.7 Computer Program for Monitoring the Process Dispersion

l) Input Variables

IR= Sample size

JC= Number of quality characteristics per inspected item

x(J,L) = Measurement of the Lth quality characteristic on the

Jth sampling item

where L = 1, 2,

J = l, 2,

... ,

. . . ' JC;

IR •

CHIK = Chi-square upper fractile value with d.f. = JC(JC+l)/2

PVI(I,J) = Inverse of standard variance-covariance matrix

DPVL = Log of determinant of standard variance-covariance matrix.

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2) Input Format

Variables

IR, JC

DO J = l, IR

(x{J,L), L = l, JC)

CHIK

DO I= l, JC

( PV I ( I , J) , J = l , JC)

DPVL

54

Format

(215)

(8Fl0.4)

{Fl0.4)

(8Fl0.4)

(Fl0.4)

3) FORTRAN Listing of Main Program

See Appendix B.

4.8 Examples of Computations Involved in Monitoring Dispersion of the Current Manufacturing Process

In Chapters 2 and 3, 30 samples of 20-tablet size were used to

prove that the manufacturing process was stable with respect to

dispersion as well as central tendency. It is expected that the

stability of the manufacturing process will continue until the occurrence

of some assignable cause that upsets the process. The standard value

for the central tendency is determined by management as

!!_' = (250.1689 2.5027)

and the standard value for the variance-covariance matrix is determined

by management as

V = [13.4596 0.4301

0. 4301]

0.0213

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55

The inverse of the matrix Vis computed as

v-l = [ 0.2094 -4.2291

-4.2291] 132.3461

and the determinant of the matrix Vis calculated as 0.1017. The type

one error for the following examples is one percent.

Example A

The 31st sample of 20-tablet size is taken from the current manu-

facturing process and the sample variance-covariance matrix is computed

as

S = [14.0000 0.4000

0.4000] 0.0220

Assume that the central tendency is under control. Management is now

interested in whether the current manufacturing process is still under

control. Here, n = 20 and k = 2. The upper fractile of the Chi-

square distribution with 3 degrees of freedom and one percent of type

one error is 11.3000.

The determinant of the matrix Sis computed as 0.1480 and the trace

of (sv-l) is equal to 2.6033, and the test statistic

L = n {Ln(IVI/ISI) - k + tr(SV-l )}

= 20 [Ln(O. 1017/0.1480) - 2 + 2.6033]

= 4.5580

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Since the test statistic, L, is less than the upper fractile of

Chi-square distribution, it is concluded that the process is in control

and it is more economical to leave the process alone.

Example B

Suppose the results of the 32nd sample of 20-tablet size gives the

variance-covariance matrix

S = [15.0000 0.5000

0.5000] 0.0450

Assume that the central tendency is under control. Management now is

interested in whether the current manufacturing process is still under

control. Again, n = 20 and k = 2. The upper fractile of the Chi-square

distribution with 3 degrees of freedom and one percent of type one error

is 11.3000.

The determinant of the sample variance matrix Sis 0.425, the trace

of (SV-l) is equal to 4.8674, and the test statistic

L = n {Ln(!VI/ISI) - k + tr(sv-l )}

= 20 [Ln(0.1017/4250) - 2 + 4.8674]

= 28.7480

Since the test statistic, L, exceeds the upper fractile of Chi-

square distribution, the process is said to lack control and further

investigation is needed to locate the cause. For ingredient A, the

sample variance, s2, is 15.00 and the null hypothesis is

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57

H0: cr 2 = 13.4596

tested against the alternative hypothesis

2 a f 13.4596 .

The test statistic

c = (n-1)s2 2 a

= 19 X 15.00/13.4596

= 21 . 17 44

The upper fractile of Chi-square distribution with 19 degrees of freedom

and 99.5 percent type one error is 38.60, and the lower fractile of

Chi-square distribution with 19 degrees of freedom and 0.5 percent type

one error is 6.84.

Since the test statistic does not fall in the reject region, the

dispersion for ingredient A seems to be in control. For ingredient 8,

the sample variance, s2, is 0.0450 and the null hypothesis is

H0: cr2 = 0.0213

tested against the alternative hypothesis

2 a f 0.0213

The test statistic

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C = (n-1 )S2 2

(J

= 19 X 0.0450/0.0213

= 40.1408

58

Since the test statistic exceeds the upper fractile of Chi-square

distribution with 19 degrees of freedom and 99.5 percent type one error,

the dispersion of ingredient Bis assumed to be the cause of the

disturbance. The process phase responsible for ingredient B requires

adjustment.

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Chapter 5

PROCEDURE FOR MONITORING THE CENTRAL TENDENCY

OF THE MANUFACTURING PROCESS

The purpose of this chapter is to develop an operational procedure

for monitoring the current manufacturing process with respect to the

central tendency. When the manufacturing process is out of control with

respect to the central tendency, a set of statistical tests can be used

to locate the manufacturing phases which need to be adjusted. A step-

by-step computational procedure is presented for the user's convenience.

The example discussed in previous chapters is again carried over for

further discussion.

5. l Brief Review of the Univariate Case

In the univariate case, the x-chart is usually employed for

monitoring the central tendency of the manufacturing process. The

central line is x, the upper control limit is x + A2R and the lower

control limit is x - A2R, where A2 is a constant which can be found in

most statistical quality control texts. If the sample average taken

from the current process falls outside the control limits, the manu-

facturing process lacks control and it becomes worthwhile to determine

the assignable cause. If, on the other hand, the sample mean falls

within the control limits, it is more economical to leave the process

alone. There are, however, some exceptions; sometimes the manufacturing

process is said to lack control even when the sample mean falls within

the control limits, e.g., seven points in a row fall on one side of the

59

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60

central line. A more detailed discussion is given by Duncan (6) and

Grant (11 ).

5.2 Theorems Used in the Development of the Central Tendency Monitoring Procedure

The following are some theorems which will be used in the development

of the monitoring procedure.

Theorem 5-1

The following theorem is given by Graybill (12):

If a vector y_ (lxk) is normally distributed with mean vector 0 I

and variance-covariance matrix W, then y_ By_ is distributed as the Chi-

square distribution with k degrees of freedom, if and only if that BW

is idempotent and Bis a (kxk) matrix.

Theorem 5-2

The followin9 theorem is given by Schmidt (32):

If y_ is a (lxk) vector and Tis a (kxk) symmetric matrix, then

I

Y. Ty_ =

Theorem 5-3

k I

i = l 2 t .. y. +

1 1 1

k-1 k I I i=l j=i+l

t .. y.y .. 1 J 1 J

The following theorem is given by Mood and Graybill (12):

If xi is normally distributed with mean ui and variance vii' then

(X;-Ui) 2

V •. 11

follows the Chi-square distribution with degrees of freedom n.

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61

Theorem 5-4

The fo l1 owing theorem is given by Ha 1 d (13):

If xj is normally distributed with mean ui and variance vii' then

n (x .-x/ I ---=-J -. 1 V •• J= 11

follows the Chi-square distribution with degrees of freedom (n-1), where

the x is the average.

Theorem 5-5

The following theorem is given by Hald (13):

The Chi-square distribution with n degrees of freedom can be par-

titioned into two terms; the first term has the Chi-square distribution

with one degree of freedom and the second term has the Chi-square distri-

bution with (n~l) degrees of freedom.

5.3 Development of the Central Tendency Monitoring Procedure

Assume that the dispersion of the manufacturing process represented

by the variance-covariance matrix, V, is under control and the level

of the central tendency intended to be maintained is!!.= (u1 u2 ... uk).

Suppose a sample of size n is taken from the current manufacturing

process, and the unit weight assigned to the deviation of the quality

characteristic from the standard value.

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62

-if g. Xi > u , -0 if W, = X, = u.

1 1 , -

l i if X, < U, 1 ,

where i = l, 2, ... , k. The utility function is therefore defined as

- )2 , 1 k w.n(x.-u. -n {X-!:!J v- (!-!:D - I 1 1 1

i=l V;; (5.1)

The term -n([-Q) 1 v-l (!-Q) in the exponential function represents the

total deviation amono all the major components and the sum of all the two

components interactions. - 2 k w-n(x.-u.)

The term - I 1 1 1 in the exponential . l V •• , = 11

function represents the sum of weighted deviation of all the major

components.

An analysis of the utility function just defined indicates that if

the manufacturing process is to maintain the desirable quality, then

the sample average vector,!, should be close to the desirable mean

vector, Q. Therefore, the value of the utility function would be

relatively large. On the other hand, if the current manufacturing

process is no longer producing desired quality, the sample average

vector, K, would deviate from the desirable mean vector, Q, and the

value of the utility function would be relatively small. Because the

monitoring procedure is operated in the probabilistical environment, it

is desirable to find a critical value, say c, which will have the

probability of acceptance as equal to {l-a) if the utility function

has value greater than or equal to the critical value c. Statistically,

the task is to find the critical value, c, such that

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63

Substituting equation (5.1) into the above equation gives

k -n ([-!!_) • v-1 ([-!!_) - I

i = l P[e

- 2 w.n(x.-u.) l l l

V •• l l

> c] = l

By Theorem (5-1 ), the above equation can be written as

2 k 2 -x (k) - I wix (1)

P[e i=l ~c]=l-a

By Theorem (5-5), the following equation is obtained.

P[e

k -/(1) + i(k-1) - x2(1) L w. . l l 1= c] = l - a

Use of Theorem (5-5) recursively results in

2 k -x (l)(k + l wi)

P[e i=l ] c = l - a

Taking the logarithm of the above equation gives

k P[x2 (1 )(k + l wi) Lnc] = l - a

i =l

or

Therefore,

or

2 k P[x (1) -Lnc/(k + I wi)] = l - a

i =l

- a (5.2)

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64

Substituting the c value back into equation (5.2) gives

or

2 k -x (1 ), (k + l w.)

-a i = l , ] = > e

I l k P[n ([-!!.) v- (K-U) + l

i =l

l - a

{- )2 w.n x.-u. 1 l 1

v .. 11

l - a

(5.3)

(5.4)

Now, suppose that a sample of size n is taken from the current

manufacturing process. It is assumed to have the specified variance-

covariance matrix, V, and it is desired to maintain a specified mean

vector,!!_, for this manufacturing process. The unit weight wi is assigned

to the deviation of the ith quality characteristic from the specified

mean value. The unit weights are given as

gi if x1 > Ui

Wi = l . if X, < u. 1 1 1

0 if X· 1 = u. 1

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65

where i = l, 2, ... , k, should be predetermined according to the impor-

tance of each characteristic to the function of the product. The

decision is to leave the manufacturing process alone if

k A = n (K-!:D' v- l (K-U) + I

i =l

is less than or equal to

k 2 Q = (k + L wi) x (1 ), _

i = l a.

- 2 w.n(x.-u.) 1 1 1

Vii

5.4 Identification of Characteristics Contributinq to the Central Tendency Control Problem

(5.5)

(5.6)

When the manufacturing process is out of control, the ideal proce-

dure is to have all the dimensions restored to the standard values.

In some cases, however, it is desirable to adjust a minimum number

of characteristics in order to restore the manufacturing process to

normal operation. For example, it may be technically very difficult to

adjust all the dimensions in the short time interval available; or perhaps

management intends to schedule all the major maintenance work during the

evening shift. It is therefore desirable to have some procedure for

rapidly identifying the quality characteristics which need adjustment.

Examination of the inequality portion of equation (5.4) shows that

, l k w . n (x. -u . ) 2 n (!-!D v- CK-~) + L 1 1 1

i=l Vii

(5. 7)

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66

Let y_ = (K-Q) and T = nv-1, then the first term of equation (5.7) I I

becomes Y TY. By Theorem (5-2), y_ T! can be written as

i 2 k-1 k I t .. y. + I I t .. y.y.

i=l ll l i=l j=i+l lJ l J

The second term of equation (5.7)

w.n(x.-u. )2 l l l k

I i=l V .• ,, can be written as

where d;

k 2 I d.y. i = l l l

w.n l

V .. l l

and Y; = (x. -u.). l l The right side of equation (5.7)

is essentially a constant, say h. Therefore, equation (5.7) can be

simplified as

k 2 k-1 k k 2 l t .. y. + l l ti .y.y. + I d.y. < h i=l 11 l i=l j=i+l J l J i=l l l -

With some algebraic manipulation, the above equation can be rewritten as

k 2 k-1 k L aiiyi + L i a;jY;Yj - h < 0

i=l i=l j=1+l

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67

The above equation is recognized as a k-dimensional ellipsoid.

Furthermore, this ellipsoid is the control region for the k variates

which corresponds to the k quality characteristics of interest and

the boundary of the control region is represented by

k 2 k-1 k I a .. y. + I I a .. y.y. - h = 0

i=l 11 l i=l j=i+l lJ l J (5.8)

Therefore, the process is said to be in control if the sample average

vector falls within this ellipsoid. Otherwise, the process lacks

control. Now, it can be concluded that the manufacturing process is

out of control if either of the following two statements is true:

1) Sample averages of one or more variables fall outside

their ranges on the ellipsoid.

2) No sample average falls outside its respective range,

but the combination of the sample averages falls outside

the ellipsoid.

The range for all the quality characteristics on the ellipsoid

can be calculated. When a lack of control is indicated, the sample

average of each quality characteristic may be compared with its own

range. Any sample average falling outside its range represents a

cause for concern and indicates that the corresponding phase of the

manufacturing process should be adjusted. However, when the manu-

facturing process is out of control and the sample averages of all the

quality characteristics fall within their own ranges, it is logical

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68

to say that the lack of control is attributed to interaction between

the characteristics.

Derivation of a procedure for finding the range for all the quality

characteristics can be illustrated using the two variables case.

Substitute k = 2 into equation (5.8) to obtain

The above equation can also be rewritten as

{5.9)

If the variable y1 in equation {5.9) is expressed as a dependent variable,

then the following equation can be obtained:

1/2 Yi = {-by2 [y22(b2-4ac) - 4ad] }/2a (5.10)

or

2 2 2 112 Yl = {-by2 + [b y2 - 4a(cy2 +d)] }/2a (5.11)

and

(5.12)

In order to find the extreme points for y1 on the ellipsoid, take

the first derivative of equation (5.10) with respect to y2 and set the

derivative equal to zero, i.e.,

dy l 1 2 2 - l / 2 2 dy2 = 2a {-b [y2 (b -4ac)-4ad] [y2(b -4ac)]} = o

Some algebraic manipulation results in

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69

or

2 b2d Y2 = c(b2-4ac)

(5.13)

Therefore, the solutions for y2 are

and 2 l /2

y = -(b d/f) 22

where f = c(b2-4ac). Substitute y21 into equation (5.11) and equation

(5.12) and two solutions for the variable y1, say y11 and y12 , can be

found:

(5.14)

2 1/2 1/2 y '= -b(b d/f) - [b4d/f - 4a(b2cd/f + d)]

12 2a (5.15)

Substitute y22 into equation (5.11) and equation (5.12) and another two

solutions for y1, say y13 and y14 , can be computed:

1/2 1/2 y13 = +b(b2d/f) + [b4d/f + 4a(b2cd/f + d)]

2a (5.16)

(5.17)

Hence the maximum value of y1 and the minimum value of y1 can be found

by simple comparison, i.e.,

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Maximum value of y1 = max(y11 y12 y13 Y14 ) and

Minimum value of Yi = min(y11 Y12 Y1 3 Y14).

The range for the variable y1, then, is

(maximum value of y1, minimum value of y1).

Similarly, the maximum value and the minimum value for the variable

y2 are found by rearranging equation (5.9) as

(5.18)

Express the variable y2 as the dependent variable of y1 and rewrite the

above equation as

{5.19)

Take the first derivative of the above equation with respect to the

variable y1 and set the derivative equal to zero. Algebraic manipulation

would yield the solutions for the variable y1:

1/2 y15 = +(b2d/g) (5.20)

and 2 1/2

y16 = -(b d/g) (5.21)

where g = a(b2-4ac). Substitute the values of y15 and y16 into equation

(5.19) to obtain four solutions for the variable y2, say Y23 , Y24 , Y25 ,

Y26:

(5.22)

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71

2 1/2 2 1/2 = -b(b d/g) - [b4d/g - 4c(ab d/g + d)] (5.23)

2c

(5.24)

(5.25)

The maximum value and the minimum value for the variable y2 can now be

found by simple comparison, i.e.,

Maximum value of y2 = max(y23 y24 y25 Y26 ) and

Minimum value of y2 = min(y23 Y24 Y25 Y25).

The range for the variable y2, then, is

(maximum value of y2, minimum value of y2).

For three variables case, we substitute k = 3 into equation (5.8)

and the equation becomes

or

(5.26)

If the variable y1 is expressed as the dependent variable, then, the

above equation can be rewritten as:

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72

Take the first derivative of the above equation with respect to y2 and

y3 respectively and set the resulted equations equal to zeros, i.e.,

3 Y1 0 ---

3 Y2 ( 5. 27)

and

~= 0 3 y3 (5.28)

Solve for y2 and y3 from the above equations and substitute the solutions

of y2 and y3 into equation (5.26). Then, the maximum value of y1 and the

minimum value of y1 can be obtained by comparison, and the range for

Yi is, therefore,

(maximum value of y1, minimum value of y1).

Similarly, the maximum values, minimum values and ranges for

variables y2 and y3 can be obtained. Clearly, the similar procedure can

be applied to the case of more than three variables.

In general it is necessary to adjust those dimensions

which have sample means fall outside their own boundaries. However, if

the lack of control is attributed to the interaction, then the (xi-ui) 2

of lxi-ui I can be arranged in the descending order. Then the process

engineer can adjust the dimensions which have larger deviations or choose

from those dimensions which are considered relatively easy to adjust.

5.5 Computational Procedure for Monitoring the Central Tendency of the Manufacturing Process

The standard values for the central tendency !Land the variance-

covariance matrix V are either computed from the past data or determined

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73

by management. The inverse and the determinant of V can be computed

before monitoring the process. Assume the type one error is a.

A sample of size n is taken from the current manufacturing process

and k measurements are taken on each of then individual items.

1) Assign the unit weight to the imperfect quality characteristic -if g. X, > u.

l l l -0 if W• = Xi = u.

l l -l . if x. < u.

l l l

where i = l, 2, ... , k.

2) Perform matrices multiplication f. : ([-Q.) I v-1

3) Perform the vectors multiplication

f = I.([-Q.)

4) Compute - 2 w.n(x.-u.)

l l l

Vii

where i = l , 2, ... ' k.

5) Compute k

A= nf + 2 z. i = l l

6) Compute

Q = (k + k 2 l W;) x (1 ), _

i=l a

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74

7) If the current manufacturing process with respect to the

central tendency is out of control, all the dimensions

should ideally be reset back to their standard values.

However, if for any economic or technical reason, it is

desirable not to adjust too many dimensions, then the

following procedure may provide some guidelines for

choosing the characteristics to adjust.

8) Compute the range for each characteristic using the

procedure illustrated in section 5.4.

9) If any sample mean falls outside its own range, then the

corresponding dimension must be adjusted in order to

restore the normal process.

10) If all sample means fall within their own ranges, the values

of (~i-ui) 2 or jxi-ui I may be arranged in descending order

and the characteristics with larger deviations may be

chosen for adjustment. Alternatively, those dimensions

which are considered relatively easy to adjust may be

chosen for action.

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75

5.6 Computer Program for Monitoring the Process Central Tendency

This computer program is combined with the computer program for

monitoring the process dispersion described in Section 4.7; therefore,

there is no need to duplicate those variables already entered in the

computer program.

1) Input Variables

SMALL(L) = Weighting factor for the Lth quality characteristic

if the sample average is less than the standard mean.

GREAT(L) = Weighting factor for the Lth quality characteristic

if the sample average is greater than the standard

mean.

TRUEAV(L) = Standard mean vector.

FPV(I,J) = Standard variance-covariance matrix.

CHIONE = Chi-square upper fractile value with d.f. = 1.

2) Input Format

Variables

(SMALL(L), L=l,JC)

(GREAT(L), L=l ,JC)

(TRUEAV(L), L=l ,JC)

DO I=l, JC

(FPV(I,J), J=l, JC)

CJ IONE

Format

(8Fl0.4)

{8Fl0.4)

{8Fl0.4)

(8Fl0.4)

(Fl0.4)

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76

3) FORTRAN Listing of the Main Computer Program

See Appendix B.

5.7 Example of Computations Involved in Monitoring Central Tendency of the Current Manufacturing Process

In Chapters 2 and 3, 30 samples of 20-tablet size were used to prove

the stability of the manufacturinq process. The standard value for

the central tendency was defined as

U = (250. 1689 2.5027)

and the variance-covariance matrix was defined as

V = [13.4596

0.4301 0.4301] 0.0213

The inverse of the matrix V was calculated as

v-l = [ 0.2094 -4.2291

4.2291] 132.3461

and the determinant of the V matrix was 0.1017.

For the following examples, it is assumed that the current manufac-

turing process has been proven to be in control with respect to

dispersion by previous tests. Management is now interested in knowing

whether the current manufacturing process is still under control with

respect to the central tendency. Furthermore, the unit weights for quality

characteristic deviations are assigned by management as:

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77

10 if x1 > 250.1689

w, = 0 if x, = 250.1689

5 if x, < 250.1789

and

2 if x2 > 2.5027

W2 = 0 if x2 = 2.5027

6 if x2 < 2.5027

The type one error is assigned as one percent.

Example A

A sample of 20-tablet size is taken from the current manufacturing

process and the sample averages are calculated as I K = (250.0000 2.6000) .

Management wants to know whether the manufacturing process is in

control. Here, n = 20, k = 2, w1 = 5, w2 = 2 and the 99 percent fractile

of the Chi-square distribution with one degree of freedom is 6.6300.

Substitute all these values into equations (5.5) and (5.6) to obtain

A= 27.9600 + 0.2177 + 17.8403 = 46.0120

and

Q = (2+5+2)(6.63) = 59.6700.

Since 46.0120 is less than 59.6700, the manufacturing process is

concluded in control and it is more economical to leave the process

alone than to adjust it.

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78

Example B

A sample of 20-tablet size is taken from the current manufacturing

process and the sample mean vector is computed as

x = (254.oooo 2.5000) .

Management wants to know whether the manufacturing process is in

control. Here, n = 20, k = 2, w1 = 10, w2 = 6 and the 99 percent

fractile of the Chi-square distribution with one degree of freedom is

6.6300. Substitute all these values into equations (5.5) and (5.6) to

obtain

A= 61.4460 + 218.0941 + 0.0411 = 279.5812

and

Q = (2+10+6)(6.63) = 119.3400.

Since 279,.5812 is greater than 119.3400, the manufacturing process

is out of control. A further investigation is needed for

identifying which characteristics lack control.

Let Yi = x1 - u1, y2 = x2 - u2 and substitute the variables of y1 and y 2 into equation (5.8). This gives

[ 0.2094 -4.2291] I

20(y, Y2) 132.3461

(yl Y2) -4.2291

+ 10(20)(y,2) 6(20)(y/)

- (2+10+6)(6.63) 0 + 0.0213 = 13.4596

Some algebraic manipulation results in

19.0472y12 - 169.1640y1y2 + (8280.7248y22 - 119.3400) = 0 (5.30)

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79

By equation (5.13), the solutions for the variable y2 are computed as

y21 = +0.0260 and y22 = -0.0260.

Substitute the value of y21 into equations (5.14) and (5.15)

resulting in y11 = 2.3306 and y12 = -2.5616.

Substitute the value of y22 into equations (5.16) and (5.17)

resulting in y13 = 2.5616 and y14 = -2.3306.

By inspection, the maximum value of y1 is 2.5616 and the minimum

value of y1 is -2.5616 or the maximum value of the x1 is 252.7300 and

the minimum value of the xi is 247.6073. Since the sample average of x1,

254.0000, exceeds the maximum value of x1, the phase of the manufacturing

process responsible for ingredient A is identified as the characteristic

which requires some adjustment.

Rewrite equation (5.31) in the following form:

8280.7248y22 - 169. 1640y1y2 + {19.0472y12 - 119.3400) = 0 (5. 31)

The use of equations (5.20) and (5.21) gives

y15 = +0.5455 and y16 = -0.5455.

Substitute the values of y15 and y16 into equation (5.31) to obtain

the maximum value of y2, 0.0056, and the minimum value of y2, -0.0056.

The maximum value of x2 is 2.5073 and the minimum value of x2 is 2.4971.

Since the sample average of the variable x2 is 2.5000 and it falls within

its own range, ingredient Bis concluded to be in control.

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Chapter 6

SIMULATION

The purpose of this chapter is to present two simulation studies.

Through the simulation results, the reader may see how the proposed

system responds to the situations when the manufacturing process actually

departs from the standard.

6.1 Random Number Generation

The development of the random number generating procedure is given

by Newman and Odell (28). If the random vector, I, follows a k-variate

normal distribution with mean vector G and a variance-covariance matrix

H, and where~ is a constant vector and A is a matrix of rank k, then

! =AI+~ is a random vector following a k-variate normal distribution I

with mean vector AG+ Mand variance-covariance matrix AHA. This theorem

provides a convenient means of generating a random vector! with

specified mean vector!!_ and variance-covariance V,provided two basic

requirements can be met:

1) A means of generating a random vector Z with mean vector

0 and variance-covariance matrix I is available, and

2) There is a convenient means of factoring matrix Vin the I

form of V = AA where A is a (kxk) matrix.

If these two requirements are met, then!= AZ+ U will follow normal I

distribution with mean U and variance-covariance matrix AIA = V.

80

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81

Concerning the first requirement, it is easily seen that if x1 x2 ... xk are one-dimensional random variables, independent, and all

being normally distributed with mean O and variance l, then the random I

vector f = (x1 x2 ... xk) follows a k-variates normal distribution

with mean vector O and variance-covariance matrix I. The second require-

ment can be met because the variance-covariance matrix, V, is a positive,

definite, real, symmetric matrix. For any positive definite, real,

symmetric matrix, there exists a lower triangular matrix, A, with I

positive elements on the main diagonal such that V =AA. The elements

of A can be computed recursively in the order of 11, 21, ... , kl; 22,

23, ... , kk. Since A is lower triangular aij = 0 for j > 1.

Hence,

V •• lJ

For i = j, v11 = a11 2, so that a11 = v11 112 The remaining elements in

the first column of A are then given by

for i = 1, 2, ... , k.

Once the first j-1 columns of A are computed,

j-1 2 1 /2 a .. = (v .. - I a. ) JJ JJ m=l Jm

Now if j = k, the task is completed. Otherwise,

j-1 a .. = (v .. - I a. a. )/a .. lJ lJ m=l ,m Jm JJ

for i = j+l, j+2, ... , k.

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82

6.2 Pre-analysis of Simulation

In quality control procedures, deviation of the parameters, the

central tendency and dispersion from the standard is measured in terms

of the standard deviation of the distribution of the parameters. For

example, in controlling the central tendency in the univariate case,

management would like to know the probability of detecting the deteri-

oration if the process average deviates one, two or three standard

deviations from the standard central tendency. In fact, the process

average can be either above or below the standard central tendency.

The actual process average can, therefore, take values as:

the standard central tendency,

the standard central tendency::!:_ (l)(standard deviation of

the mean),

the standard central tendency::!:_ (2)(standard deviation of

the mean), and

the standard central tendency+ (3)(standard deviation of

the mean).

The same principle can be applied to the control of the dispersion and

the actual process dispersion can also take seven values. Therefore,

it becomes necessary to consider (7)(7) - l = 48 ways in the univariate

case.

For the two variables case, the ways of the process deviating

from the standard can be laid out as:

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83

Central Tendency Di seers ion

(x) (y) (x) (y)

0 0 0 0

+l +l +l +l

+2 +2 +2 +2

+3 +3 +3 +3

The total ways of the process deviating from the standard process

is (7) (7) (7) (7) - l - 2,401 . However, in the two variables case, if

the correlation is present, then the combinations wi 11 be greatly

increased and the upper bound for the combinations is, theoretically,

infinite.

For three variables case, the total combinations for deviating

from the standard process are {7)(7)(7)(7)(7)(7) - l = 117,648.

Again, if the partial correlation is present, the number of combinations

will be greatly increased. The number of the combinations increases

with the number of quality characteristics of interest. In order to

obtain a meaningful interpretation, it seems reasonable to select some

key combinations to see how the system responds to the deteriorations

when many quality characteristics are being observed.

6.3 Simulation Study with Two Variables

In order to give a complete example, the drug manufacturing problem

used throughout this research is again used for this simulation. The

standard values for the central tendency and dispersion are determined

as

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and

I

U = (250.1689 2.5027)

V = [ 13.4596 0.4301

0.4301] 0.0213

84

respectively. The correlation coefficient is computed as 0.8033. The

unit weights for the deviations of quality characteristics from the

standard values are assigned by management as

10 if x, > 250.1689

w. = 0 if X1 = 250.1689 l

5 if X1 < 250.1689

2 if x2 > 2.5027

w2 = 0 if x2 = 2.5027

6 if x2 < 2.5027

To generate random variates for the two dimensional normal

distribution with mean vector U and varfance-covariance matrix V,

it is necessary to find a matrix A such that the variance-I

covariance matrix V can be represented by AA Based on the discussion

in Section 6.1, the elements of matrix A can be computed in the

fo 11 owing way:

= V 1/2 11

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85

and

a12 = 0.

For every combination of the simulated system departing from the

standard, 100 samples are to be generated. Each sample contains 20

individual items and each item has two measurements generated for it.

Because it is not very economical to exhaust all the combinations of

the simulated system departing from the standard, only a selected set

were simulated. Three such runs are presented here.

1) In the first run of the simulated system, the correlation

coefficient between the ingredients A and B has the standard

value. For the central tendency, the simulated process

takes values as standard process, two standard deviations

above and below the standard process. For the dispersion,

the simulated process takes values as the standard process,

two standard deviations above and below the standard process.

2) In the second run of the simulated system, the correlation

coefficient between ingredients A and B has 80 percent of the

standard value. For the central tendency and dispersion,

the simulated process has the same combination as in step 1).

3) In the third run of the simulated system, the correlation

coefficient between ingredients A and B has 110 percent of

the standard value. For the central tendency and dispersion,

the simulation process has the same combination as in

run l ) .

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86

All the simulated results are presented in Appendix F. The

simulated results seem to follow what is expected and the proposed

system appears to function reasonably well.

6.4 Simulation Study with Four Variables

The simulation work for two variables was discussed in Section 6.4.

Now, going another step further indicates how the system will respond

to the more complicated case of more than two variables. The results

of the investigation indicate that the simulation would be very

expensive. The computer program developed here can handle as many

variables as the practical situation requires with some limited

modifications. The simulation attempted in this section is a

case with four variables, say A, B, C and D. The standard values for

the centra 1 tendency and the dispersion are given as

u = (20.00 30.00 50.00 60.00)

and

1.00 1.00 1.00 1.00

1.00 2.00 1.00 1.00 V =

1.00 1.00 3.00 1.00

1.00 1.00 1.00 4.00

The partial correlation coefficients between variables were calculated as

Variables Partial Correlation Coefficient

( 1 , 2) = 0.7071

( 1 , 3) = 0.5774

( 1 ,4) = 0.5000

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87

(2.3) = 0.4082

(2,4) = 0.3536

(3,4) = 0.2887

The unit weight for the imperfect quality characteristic with respect

to the central tendency is assigned as

Wl ={ 1.00 3.00

W2 = { 3.00

2.00

W3 = { 5.00

1.50

, { 3.00 w -4 - 0.50

if x(A) > 20.00

if x(A) < 20.00

if x(B) > 30.00

if x(B) < 30.00

if x(C) > 50.00

if x(C) < 50.00

if x(D) > 60.00

if x(D) < 60.00

Originally, it was planned to simulate all the combinations with

three levels for each variance and mean. Using a sample size of 20 and

a simulated sample number of 100, this required CPU time on the IBM

360/50 of approximately 80 hours, and was not economically feasible.

Therefore, the plan for this study was revised as follows:

l) Hold all means as the standard values and take dispersion

values as standard dispersion, two standard deviations

above and below the standard dispersion for all four

variables.

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88

2) Hold all variances as the standard values and take central

tendency values as standard central tendency, two

standard deviations above and below the standard central

tendency for all four variables.

For each of these runs, the CPU time on an IBM 360/50 was approximately

80 minutes. The simulated results are presented in Appendix G. The

simulated results seem to match what is expected and the proposed system

appears to function reasonably well.

6.5 Computer Program for Simulation

l) Input Variables

IX= Random number initiator; it has to be a five digit number

with last digit an odd number

R0CF = Multiple of correlation coefficient away from the

standard correlation coefficient

CHI0NE = Chi-square upper fractile value with d.f. = l

CHIK = Chi-square upper fractile value with d.f. = JC(JC+l)/2

IR= Sample size

JC= Number of quality characteristics

AVE(L) = Standard mean vector

PV(I,J) = Standard variance-covariance matrix

PVI{IMJ) = Inverse of standard variance-covariance matrix

SPV{L) = Standard deviation for the variance of the Lth variable

MM= Number of sample for every combination of departure from

the standard process

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89

GREAT(L) = Weighting factor for the Lth quality characteristic if

the sample average is greater than the standard mean

SMALL(L) = Weighting factor for the Lth quality characteristic if

the sample average is less than the standard mean

NM(L) = Maximum number of S.D. to be varied for the mean of Lth

quality characteristic

NV(L) = Maximum number of S.D. to be varied for the variance of

the Lth quality characteristic

ZM(J,L) = Actual number of S.D. departed from the standard mean

of the Lth quality characteristic

ZV(J,L) = Actual number of S.D. departed from the standard mean

of the Lth quality characteristic.

2) Input Format

Vari.ables

IX

ROCF

CHIONE, CHIK

IR, JC

(AVE(L), L = l, JC)

DO I= l, JC

( PV ( I , J) , J = 1 , JC)

DO I= l, JC

(PVI(I,J), J = 1, JC)

(SPV(L), L = l, JC)

MM

(!5)

(FlO.4)

(2Fl0.4)

(215)

(8Fl0.4)

(8Fl0. 4)

(8FlO.4)

(8FlO.4)

(15)

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(GREAT ( L ) , L = l , JC )

(SMALL(L), L = l, JC)

(NM(L), L = l, JC)

(NV(L), L = l, JC)

DO J = l, JC

(ZM(J,L), L = l, NM(J))

( ZV ( J , K) , L = 1 , NV ( J ) )

90

(8Fl0.4)

(8Fl0.4)

(1015)

(1015)

(8Fl0.4)

(8Fl0.4)

3) FORTRAN Listing of Main Program for Two Variables Case

See Appendix C.

4) FORTRAN Listing of Main Program for Four Variables Case

See Appendix 0.

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Chapter 7

SUMMARY AND RECOMMENDATIONS

Previous chapters of this research were devoted to the development

of the quality control procedure for the multivariate situation. In

this chapter, a summary of the entire work is presented and recom-

mendations are made concerning areas for further study.

7. l Summary

The primary purpose of this dissertation is to develop an appli-

cation system which can be used for the quality control areas. Because

of the nature of the application, the computational procedures and

numerical examples are particularly emphasized. An antidiarrheal

tablet manufacturing process was used as an illustration. The tablet

preparation contained two active drug ingredients, A and B. First of

all, it was desired to prove the stability of the manufacturing

process with respect to the dispersion. For illustrative purpose, 30

samples of 20-tablet size were taken at relatively equal time intervals

during the past operation. Here, the number of samples, m, is 30, the

sample size, n, is 20, and the number of quality characteristics, k, is

2. All the measurements taken in the ith time interval were designated

by

=

xi,2,1

. xi, l ,20]

X. 2 2 ' ' ' X. 2 20 ,, ' ,, '

91

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92

The sample variance-covariance matrix for the ith time interval,

Si' was computed based on Xi. The pooled sample variance-covariance

matrix, SP, was computed from the values of all Si. The R-statistic

is then calculated according to the formula:

2k2 + 3k - 1 m2 - 1 R = 2.3026 x {l - [6(k+l )(m-1) x m(n-1)]

k x [m(n-1) Log I Sp! - (n-1) i~l LogjSi !]}

The R-statistic was found to be 53.8690 and the corresponding Chi-square

table value was found to be 113.00. Since the R-statistic was less

than the critical value, it was concluded that the manufacturing process

was reasonably stable with respect to dispersion. Next, it was desired

to prove the stability of the manufacturing process with respect to the

central tendency. The following were computed:

m I

T = l X X i = 1

= [37,558,460.0000 375,919.8000

375,919.8000] 3,770.9130

m A = I

i = l n (x. -x) (x. -x) =

-. - [431.1323 -l - -l - 13.2191

13.2196] 0.6410

[37,558,460.0000

E=T-A= 375,906.5000

W = ffi = 0.9501

375,906.5000]

3,770.2720

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93

and va = 29, ve = 570, and k = 2. The W-statistic was converted to an

F-statistic. The value of the converted F-statistic was 0.0501 and its

corresponding F-table value was 1.48. Since the value of 0.0501 was

less than 1.48, it was concluded that the manufacturinq process was

reasonably stable with respect to central tendency, too. At this time,

management indicated satisfaction with the manufacturing process.

The standard values for the dispersion matrix and the central tendency

were determined as

and

[13.4596

V = 0. 4301

I

0.4301] 0.0213

U = (250. 1689 2.5027)

The determinant of the standard dispersion matrix was computed as 0.1017.

The 31st sample of 20-tablet size was taken; the sample mean and

the sample dispersion matrix were calculated as

and

X = (250.0000 2.6000)

s = [14.0000

0.4000 0. 4000] 0.0220

respectively. The L-statistic was calculated by the following formula:

L = n[Ln(jVj/jSj) - k + tr(SV- 1)]

and the L-statistic was found to be 4.5580 and the corresponding Chi-

square table value was found to be 11.3000. Because 4.5580 was less

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94

than 11.3000, it was concluded that the current manufacturing process

was under control with respect to the dispersion. To investigate

whether the central tendency of the manufacturing process was still under

control, management assigned the weight factor w1 = 5 to ingredient A

and the weight factor w2 = 2 to ingredient B.

and

- 2 w.n(x.-u.) l l l

V •• 11

= 46.0120

Since A was less than Q, it was concluded that the current manu-

facturing process was also under control with respect to central

tendency. Therefore, it was more economical to leave the process alone.

Operational procedures and examples for the cases lacking control were

also discussed. Simulations were developed to show how the system

responded to the situations when the manufacturing process actually

departed from the standard. The simulation results showed that the

proposed system was adequate to perform this function.

7.2 Areas for Further Study

1) Terminal Operation: Because of the large amount of data

manipulation, an on-line computer support seems ioost

appropriate for this case. Through the terminal, the

data can be entered to permit a quick decision based on

the calculated results.

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95

2) Trend Analysis: According to the quality control chart

for the univariate case, the manufacturing process is

said to be out of control when seven consecutive points

fall at one side of the central line but with no point

falling outside the limits. For the multivariate

situation, it would be helpful to develop some kind of

trend analysis for detecting the deterioration when the

manufacturing process degrades slowly.

3) Warning Zones: In the quality control chart

for the univariate case, when sample points fall in the

warning zone, the quality special attention should be paid

to preventing the process from departing from the

standard. For the multivariate situation, the warning

zone should be a good means of getting the engineer's

attention before the process goes too far out of control.

4) Sample Size: The optimal sample size in the multivariate

case, intuitively, should be some function of the number

of quality characteristics to be controlled and of the

various costs such as the cost of inspection, cost of

failing to detect the lack of control and cost of false

alarms, etc.

5) Time Interval Between Sampling: The optimal time interval

between sampling should be derived from some cost function.

The above areas are recommended for further study.

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BIBLIOGRAPHY

1. Anderson, T. W., An Introduction to Multivariate Statistical Analysis, John Wiley & Sons, Inc., New York, 1966.

2. Barnard, A. G., "Control Charts and Stochastic Process," Journal of the Royal Statistical Society, Series B, Volume 21, No. 2, 1959.

3. Bartlett, M. S., "Test of Significance in Factor Analysis," British Journal of Psychology Statistics, Sec. 3, 1950.

4. Box, G. E., "A General Distribution Theory for a Class of Likelihood Criterion," Biometrika, Vol. 36, 1949.

5. Chakravati, I. M., Laha, R. G., and Ray, J., Handbook of Methods of Applied Statistics, John Wiley & Sons, Inc., New York, 1967.

6. Duncan, A. J., Quality Control and Industrial Statistics, Richard D. Irwin, Inc., Homewood, Illinois, 1965.

7. Duncan, A. J., "The Economic Design of x-Chart Used to Maintain Current Control of Process," Journal of the American Statistical Association, Vol. 51, 1956.

8. Duncan, A. J., "The Economic Design of x-Charts When There is A Multiplicity of Assignable Causes," Journal of American Statistical Association, Vol. 66, 1971.

9. Ghare, P. M. and Torgersen, P. E., "The Multicharacteristic Control Chart," Journal of Industrial Enqineerinq, June 1968.

10. Goel, A. L., Jain, S. C., and Wu, S. M., "An Algorithm for the Determination of the Economic Design of x-Charts Based on Duncan's Model," Journal of the American Statistical Association, Vo 1. 6 3 , 1 968 .

11. Grant, E. L., Statistical Quality Control, 3rd Edition, McGraw-Hill Book Company, New York, 1964.

12. Graybill, F. A., An Introduction to Linear Statistical Models, McGraw-Hill Book Company, New York, 1961.

13. Hald, A., Statistical Theory With Engineering Applications, John Wiley & Sons, Inc., New York, 1952.

14. Hartley, H. 0., ''The Range in Random Samples," Biometrika, Vol. 32, 1942.

96

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97

15. Jackson, J. E., 11 Quality Control Methods for Two Related Variables, 11

Industrial Quality Control, January 1956.

16. Jackson, J. E., "Quality Control Methods for Several Related Variables, 11 Technometric, Vol. 1, No. 4, November 1959.

17. Korin, B. P., 11 0n the Distribution of a Statistic Used for Testing a Covariance Matrix, 11 Biometrika, Vol. 56, 1969.

IH. Kramer, C. Y. and Jensen, D. R., "Fundamentals of Multivariate Analysis--Part I. Inferences About Means," Journal of Quality Technology, Vol. l, No. 3, July 1969.

19. Kramer, C. Y. and Jensen, D. R., "Fundamentals of Multivariate Analysis--Part II. Inference About Two Treatments, 11 Journal of Quality Technology, Vol. 2, No. l, January 1969.

20. Kramer, C. Y. and Jensen, D. R., 11 Fundamentals of Multivariate Analysis--Part III. Analysis of Variance for One-Way Classi-fication,11 Journal of Quality Technology, Vol. 1, No. 4, October 1969.

21. Kramer, C. Y. and Jensen, D. R., 11 Fundamentals of Multivariate Analysis--Part IV. Analysis of Variance for Balanced Experiments, 11 Journal of Quality Technology, Vol. 2, No. 1, January 1970.

22. Kullback, S., Information Theory and Statistics, John Wiley & Sons, Inc., New York, 1959.

23. Lawlty, D. N., 11 The Estimation of Factor Loadings by the Method of Maximum Likelihood," ProLeeding of the Royal Society uf Edinburgh, 1939-1940.

24. Montgomery, D. C. and Klatt, P. J., "Economic Design of T2 Control Chart to Maintain Current Control of a Process, 11 Manaqement Science, Vol. 19, No. 1, September 1972.

25. Montgomery, D. C. and Klatt, P. J., "Minimum Cost Multivariate Quality Control Tests, 11 AIIE Transactions, June 1972.

26. Montgomery, D. C. and Wadsworth, H. M., 11 Some Techniques for Multi-variate Quality Control Applications, 11 Transactions of the ASQC, Washington, D. C., 1g72,

27. Morrison, D. F., Multivariate Statistical Methods, McGraw-Hill Book Company, New York, 1967.

28. Newman, T. G. and Odell, P. L., The Generation of Random Variation, Hafner Publishin9 Company, New York, 1971.

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98

29. Noether, G. E., "Use of the Range Instead of the Standard Deviation," Journal of the American Statistical Association, Vol. 50, 1955.

30. Ostle, B. and Steck, G. P., "Correlation Between Sample Means and Sample Ranges, 11 Journal of the American Statistical Association, Vo 1 . 54, 1959.

31. Pages,!:. S., 11 A Modified Control Chart with Warning Limits, 11

Biometrika, Vol. 49, 1962.

32. Schmidt, J. W., "Mathematical Operations Research--Class Handout," Department of Industrial Engineering and Operations Research, Virginia Polytechnic Institute and State University, Blacksburg.

33. Shewhart, W. D., Statistical Method from the Viewpoint of Quality Control, Department of Agriculture, Washington, D. C., 1939.

34. Stein, F. M., Introduction to Matrices and Determinants, Wadsworth Publishing Co., Belmont, California, 1967.

35. Wall, F. J., "The Generalized Variance Ratio or U-Statistic, 11

Technical Report, The Dikewood Corporation, Albuquerque, New Mexico, 87106.

36. Weiler, G. H., "New Type of Control Chart Limits for Means, Ranges and Sequential Runs," Journal of the American Statistical Association, Vol. 49, 1954.

37. Weiler, G.' H., 11 0n the Most Economical Sample Size for Controlling the Mean of a Population," The Annals of Mathematical Statistics, Vol. 23, 1952.

38. Wilks, S.S., "Certain Generalizations in the Analysis of Variance," Biometrika, Vol. 24, 1932.

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The vita has been removed from the scanned document

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Appendix A

MAIN PROGRAM FOR TESTING STABILITY OF PROCESS

100

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C C MAIN PROGRAM FOR TESTING THE STABILITY OF PROCESS C

1000 1010 1100 1101 1110 1200

1250

1308 1350 1400 1450

C

COMMON /BLOKA/ AVE(5),XBAR(5),SV(5,5),PV(5,5),PVJ(5,S),DEV(5), X C RE AT ( 5 ) , S MAL L ( 5 ) , X ( 5 0, 5 ) , T RU EA V ( 5 ) , F P V ( 5 , 5 ) 'COMMON /BLCKil/ DPV,NOOC,IX,DOCC,~CCC,IR,R,JC,C,DPVL

COMMON DET COMMO~ /BLCKH/ SS(l0,10),TOT(lO) DIMENSION U(40,20,5),DS(40),SP(5,5),A(S,5),AA(5,5),XBAL(40,5) DIMENSION TT(40,20),T(5,5),G(5),Y(40,5),E(5,5) FORMAT (3 I 5) FCRMAT (Fl0.4) FORMAT (8Fl0.4) FORMAT (4Fl2.2) FORMAT (15,Fl0.4) FORMAT (/, 1 PROCESS IS NOT STABLE WITH RESPECT TO DISPERSION

X ', 2F 12. 4) FORMAT(/,' PROCESS IS STABLE WITH RESPECT TO DISPERSION

X ',2Fl2.4) FORMAT ( 1 PROCESS IS STABLE WITH RESPECT TO CENTRAL TENDENCY') FORMAT (' F-DISTR IBUTION IS NOT APPROPRIATE 1 )

FORMAT(' INDEX IS INVALID 1 ) FORMAT ( 1 PROCESS IS NOT STABLE WITH RESPECT TO CENTRAL TENDENCY

X I )

C TEST STABILITY OF PRCCESS WITH RESPECT TO DISPERSION C

READ (5,lCOC) IR,JC,M READ (5,1010) TABLEV R=IR AN=IR AK=JC

0

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AM=M S DS=O .O DO 1500 I=l,JC G(Il=C.O DO 1500 J-=1,JC A(I,J)=O.O TCI,Jl=O.O

1500 SP(I,J)=O.O DO 20CO I=l,M DO 2500 J=l, IR READ (5,1100) (X(J,Ll,L=l,JC)

2500 CONTINUE CALL MANDV DO 2440 LA=l,JC G(LA)=G(LA)+XBAR(LA) XBAL(I,LA)=XBAR(LA) DO 2430 LB=l,JC SP(LA,LB)=SP(LA,LB)+SV(LA,LB) T(LA,LB)-=T(LA,LR)+SS(LA,LB) PV(LA,LB)=SV(LA,LB)

2430 CONTINUE 2.'.t40 CUNTINUE

CALL DETER OS( I)=.'\LOG!O(OET) SDS=SDS+DS(I)

2000 CCJNTINUE DO 27CO 1-=1,JC DO 2700 J=l,JC PV(I,J)=SP(l,J)/AM

2700 C !JNTI NUE CALL DETER OSP=ALOGlO(CJET)

.... 0 N

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AZ=2.0*AK*AK+3.0*AK-l.O oB= AM*AM-1.0 CC=6.C*(AK+l.O)*(AM-l.O) DD=AM*( AN-1.0) R=2.3026*(1.0-(AZ*B8/CC*DD))~(DD*DSP-(AN-l.O)*SDS) IF (R .LE. TABLEV) GO TO 5000 WRITE (6,1200) R,TABLEV GO TO 6001

5000 hRITE (6,1250) R,TABLEV 6001 CONTINUE C C TEST STABILITY OF PROCESS WITH RESPECT TO CENTRAL TENDENCY C

READ (5,1100) VA,VE READ (5,1110) INDEX,TABLEM DO 4550 1=1,JC DO 4600 J=l,JC PV( I,J)=T(I,J)

4600 CONTI~UE 4550 CONT I NUE

CALL DETER DfTT=DET DO 4640 J=l ,JC

4640 G(J)=G{J)/AM DO 50 0 5 I= 1 , M DO 5500 l= 1,JC Y(I,L)=XBAL(J,L)-G(LJ

5500 CONTINUE 5005 CONTINUE

DO 59<;9 L=l ,M DO 6000 I=l,JC DO 65CO J=l,JC

__, 0 w

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6500 6000 59<;9

7000

8500 8000

A(I,J)=Y{I,I)*Y(I,J)+A(I,J) CONTINUE CONTINUE CONTINUE DO 7000 I=l,JC DO 7000 J=l,JC A(I,J)=AN*A(I,J) P V { I, J) =A ( I, J ) C>JNTINUE CALL DETER DETA=OET DO 8000 I=l,JC 00 8500 J=l ,JC EC I,J)=T( I,JJ-A(I,J) PV ( I, J )= E (I, J) CGrHI NUE CONTINUE CALL DETER DETE=DET W=DETE/DETT ~RITE (6,1100) ~,TABLEM IF (INDEX .EQ. 1) GG TO 510 IF (INDEX .EQ. 2) GO TO 520 IF { l~DEX .E:Q. ~) GC TO 530 WR.I TF ( 6, 1400) INDEX GO TO 2450

510 IF (W .LT. TABLE~) GO TO 2410 515 WRITE (6,1450)

GO TO 2450 5 2 0 I F ( V A • N f. l • 0 ) GO TO 2 412

F=(l.O-W)*(VE+VA-AK)/(W*AK) WRITE (6,1100) F,TABLEM

_,

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IF (F .GT. TABLEM) GO TO 515 GO TO 2410

2 412 I F ( V A • N E. 2 • 0 ) GC TO 2 414 F=(l.C-SQRT(Wll*(V[+VA-AK-1.0}/(SQRT(W)*AK) v,RITE (6,1100) F,TABLEM _ IF (F .er. TA8LEM) GO TO 515 GO TO 2410

2414 IF (AK .NE. 1.0) GO TO 2416 F={l.0-W)•VE/(W*VA) wRITE (6,1100) F,TABLEM IF (F .GT. TABLEM) GO TO 515 GO TO 2410

2416 IF (AK .r~E. 2.0) GO TO 2418 F=(l.O-SQRT(W)*(VE-1.))/(SQRT(W)*VA) WRITE (6,1100) F,TABLEM IF (F .GT. TABLEM) GO TO 515 GO TO 2410

2418 WRITE (6,1350) GO TO 2450

530 B=VE-(AK-VA+l.0)/2.0 B=-8*ALOG(W) WRITE (6,1100) B,TABLEM IF (8 .GT. TABLEM) GO TO 515

2410 WRITE (6,1308) 2450 STOP

END

...... 0 u,

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Appendix B

MAIN PROGRAM FOR MONITORING PROCESS

106

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C C MAIN PROGRAM FOR MONITORING THE MANUFACTURING PROCESS C

C C C 1130 1140 1000 1100 1164

2000

2100

2200

CO~MUN /3LOKA/ AVE(5),XBAR(5),SV(5,~),PV(S,5),PVI(5,5),DEV(5), XGREAT(5),SMALL(5),X(S0,5),T~UEAV(5),FPV{5,5)

COMMON /glCKB/ DPV,NOOC,IX,COCC,~OOC,IP,R,JC,C,DPVL CO~MON /BLOKD/ CHIONE,CHIK,DSV CUMMON /BLOKG/ DET DIMENSION F(5J,ZC5),TRS(5,5),WEIG(5)

MONITORING OF THE DISPERSION

FORMAT ( 1 DISPEPSION IS CUT CF CGNTROL') FORMAT ( 1 MEAN IS OUT OF CONTROL ') FORMAT (215) FORMAT (8Fl0.4) FORMAT ( 1 END OF TEST 1 )

REAO (5,1000) IR,JC R=IR DO 2000 l=l,IR READ (5,llOC) (XC I,J) ,J=l,JC) CCN TINUE READ (5,1100) CHIONE,CHIK READ (5,ll0C) CS~ALL(J) ,J=l,JC) READ (5,1100) (GREAT(J},J=l,JC) READ (5,1100) CTPUfAV(J),J=l,JC) DO 2100 I=l,JC READ (5,1100) (FPVCI,J),J=l,JC) CONTINUE DO 2200 I=l ,JC READ (5,1100) (PVI(I,J),J=l,JC) CCNTINUE

...... 0 '-I

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READ (5,1100) DPVL TR=O. FIR=O. S EC=O. Tvl=O. CALL MANDY OD 1155 I=l,JC DO 1155 J=l ,JC PV( I,Jl=SV( 1,J)

1155 CONTINUE CALL DETER DSV=DET DO 200 1=1,JC DO 180 J=l,JC TRS(I,J)=O. DO 170 K=l,JC TRS{I,J)=TRS(I,J)+SV(l,K)*PVI(K,J)

170 CONTINUE 180 CONTINUE 200 CONTINUE

DO 210 J=l,JC TR=TR+TRS(J,J)

210 CON Tl NUE OSVL=ALCG(DSV) STAT=R*(DPVL-DSVL-C+TR) IF (STAT .GE. CHIK) WRITE (6,1130)

C C MGNITORING OF THE CENTRAL TENDENCY C 260 DO 370 J=l,JC

Z(J)=XBAR(J)-TRUEAV(J) IF (XBAR(JJ .GE. TRUEAV(J)) GO TO 350

__,

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W E I G ( J ) =SM A LL ( J ) GO TO 360

350 ~EIG(J)=GREAT(J) 360 TW=TW+WEIG(J) 370 CON TI NUE 390 CRIT=CHIONE*(C+TW)

00 "•10 1=1, JC F(l)=O. DO 400 J=l,JC

400 F(l)=Z(J)*PVl(J,I)+F(I) 410 CONTINUE

DO 420 J=l,JC FIR=FIR+F(J)*Z(J) SEC=SEC+R*WEIG(J)*Z(J)**2/FPV(J,J)

420 CON TI NUE FIR=FIR*R ST=FIR+SEC IF (ST .GT. CRIT) WRITE {6,1140) hRITE (6,1164) STOP END

..... 0 1.0

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Appendix C

TWO VARIABLES SIMULATION MAIN PROGRAM

110

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C C MAIN PRCGRAM FOR SIMULATION ( TWO VARIABLES) C

110 120 230 250 350

351

352 360 373

805

COMMON /BLOKA/ AVE(5),XBAR(~),SV(5,5),PV(5,5),PV1(5,5),DEV(5), XGREAT(5),SMALL(5),X(50,5),TRUEAV(5),FPV(5,5)

COMMON /BLC~B/ DPV,NOOC, IX,DOOC,MOOC,IR,R,JC,C,DPVL cu~~ON /BLOKC/ A(5,5) COMMON /BLOKD/ CHIONE,CHIK,OSV CO~MON /BLGKG/ DET OIMENSICN SPV(5,5),DVE(5) DIMENSION NM(lO),NV(lO),ZM(5,10),ZV(5,10) ,R0(5,5),FPV(5,5) OIMENSICN ID(20) FORMAT ( 8Fl0.4) FORMAT '1015) FORMAT (4Fl 0.6) FORMAT (lHl,///) FORMAT (I,' S.O. AWAY FROM STANDARD PROCESS

XMEAN TOTAL . ) FORMAT (/,' VARIANCE

XERCENT PERCENT 1 ) FORMAT (X,4Il0,2I9,2X,I9,/) FORMAT (/) FORMAT (/, 1

X. 0 • C • 0 .o. C. ' ) FORMAT (lOF5.l) REAU (5,120) IX READ (5,110) ROCF

( B)

READ (5,230t CHIONE,CHJK READ (5,120} IR,JC READ (5,110) (AVE(J),J=l,JC) DO 270 1=1,JC

CENTRAL TENDENCY

(A) (8) (A)

DISPERSION

PERCENT

o.o.c.

p

0

..... ..... .....

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READ (5,110) (PV(I,JJ,J=l,JC) 270 CONTil\:UE

DO 2 8 0 I = 1 , JC PEAD (5,110) ( P VI ( I, J) , J= 1, JC)

280 CON TI NUE DO 290 I=l,JC PEAD (5,110) SPV(I,I)

290 CONTINUE READ (5,120) MM

300 R !:AD ( 5,110) (GREAT(J),J=l,JC) READ (5,110) (SMALL(J),J=l,JC) READ ( 5, 12 0 ) (NM( I) ,1=1,JC) READ (5,120) (NV(IJ,I=l,JC) DO 308 1=1,JC NMDUM=NM( I) NVDUM=NV( I) READ (5,805) ( ( I, L ) , L = 1, NMDUM) ...... READ (5,8C5) ( ZV( I, L) ,l=l ,NVDUM) ......

N 308 CONTINUE

R=IR C=JC DPV=PV(l,l)*PV(2,2)-PV(l,2}**2 CPVL=ALCG{DPV) ~ 1Rl TE (6,250) w RITE (6,350) \<.RITE (6,351) wRI TE (6,373) WRITE (6,360) DO 301 l=l,JC TRUEAV( I )=AVE( I) DVE(l)=SQRT(PV(I,I))/SQRT(R) DO 302 J=l,JC

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FPV(l,J)=PV(I,J) 302 CONTINUE 301 CONTINUE

00 3777 I=l,JC 3777 RO(I,I)=l.O

JCA=JC-1 DO 317 l=l,JCA l=I+l DO 317 J=L,JC RO (I, J) = PV ( I, J ) /SQRT ( PV ( I, I ) *PV ( J, J) ) RO(J,l)=RO(I,J)

317 CONTINUE NV2=NV(2) ~Vl=NV(l) DO 3200 L2=1,NV2 PV(2,2)=FPV(2,2)+ZV(2,L2)*SPV(2,2) DO 3300 Ll=l,NVl PV(l,l)=FPV(l,l)+ZV(l,ll)*SPV(l,1) PV(l,2)=RC(l,2)*SCRT(PV(l,ll*PV{2,2)) PV( 2, ll=PV( 1,2) CALL CONVE2 r-. M2=N~ (2) I\' i-11 = N M ( 1 ) DO 4200 M2=1,NM2 AVE(2)=TRLE~V(2)+ZM(2,M2)*DVE(2) DO 4300 Ml=l,NMl AVE(l)=TRUEAV(lJ+ZM(l,Ml)*DVE(l) OOOC=O. MOOC=O NOOC=O DO 1500 KK=l,MM CALL RANGE2

...... ...... w

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1500

4300 4200 3300 3200

CALL MANDV CALL TEST CONT lNUE AA=NOOC AMOOC=MOOC BB=MM PER=AA*lOO. 0/BB APER=lOC.O*AMOOC/88 DPER=lOO.O*COCC/BB ID ( 1) = Z V ( 2, l2) ID( 2)=ZV( 1,Ll) ID(3)=ZM(2,M2) ID(4J=ZM(l,,-,l) l0(5)=DPER l0(6)=APER 10(7)=PER \-,RITE ( f,352) ( ID(l ),1=1,7) PUNCH 352,IC(l),10(2),10(3),10(4),ID(S),I0(6),ID(7) CONTINUE CONTINUE CONTINUE CONTINUE STOP END

--.i:,.

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Appendix D

FOUR VARIABLES SIMULATION MAIN PROGRAM

115

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C C MAIN PRCGRA~ FOR SIMULATION (FOUR VARIABLES ) C

110 120 230 250 350

351

352 360 373

COMMON /BLCKA/ AVE(5),XBAR(5J,SV(5,5J,PV(5,5),PVl(5,5),DEV(5), XGREAT(5),SMALL(5),X(50,5),TRUEAV(S),FPV(5,5)

COMMON /BLOK8/ DPV,NOOC,IX,DOCC,MCCC,IR,R,JC,C,DPVL COMMON /BLOKC/ A(5,5)

CHIO~E,CHIK,DSV COMMON /BLCKG/ DET DIMENSION SPV(5,5),CVE(5) DIMENSION NM(lO),NV(lO),ZM(5,10),ZV(5,lO),R0{5,5),FPV(5,5) DIMENSION 10(20) FORMAT (8Fl0.4) FORMAT (1015) FORMAT (4Fl0.6) FORMAT (lHl,///) FORMAT(/,' S.D. AWAY FRCM STANDARD PROCESS DISPERSION

XMEAN TOTAL 1 )

FORMAT(/,' VARIANCE CENTRAL TENDENCY PERCENT XERCENT PERCENT ')

FORMAT (8I5,219,2X,19,/) FORMAT (/) FORMAT (/,' (0) (C) (8) (A) (D) (C) (B) (A) o.o.c.

x.o.c. o.o.c. 1 )

805 FORMAT (lOFS.l) READ ( 5,120) IX READ (5,110) ROCF READ (5,230) CHIONE,CHIK READ (5,120) IR,JC READ (5,110) (AVE(J),J=l,JC) DO 210 I=l,JC READ (5,110) (PV(I,J),J=l,JC)

p

0

..... ..... °'

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270 CONTINUE DO 2 8 0 I = 1 , JC R EAO (5,110) (PVI(I,J),J:1,JC)

280 CONTINUE DO 290 l=l,JC READ ( 5, 110) SP V ( I, I)

290 CONTl"UE READ (5,120) MM

300 READ ( 5, 110 ) (GREAT(J),J=l,JC) READ (5,110) (SMALL<J),J=l,JC) PEAD (5,120) (NM( I) ,I=l ,JC) READ (5,120) (NV ( I ) , I= l , JC J DO 3 0 e I= l , JC M1DUM=N M ( I ) NVDUM=NV(I) READ (5,8C5) ( Z M ( I , L) , L = 1 , WW UM ) READ (5,805) ( Z V ( I, L) , L = 1, N VD UM) ......

308 CONTI f\UE ...... ...., P=IR C=JC CALL CETER 0 PV=DET DPVL=ALOG( OPV) wRITE (6,250) WRITE (6,350) WRITE (6,351) hRITE (6,373) WRITE (6,360) 00 301 I= l, JC TRUEAV(I)=AVE(I) DVE(l}=SQRT(PV(l,I))/SQRT(R) DO 302 J::::1,JC

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FPV(I ,J)=PV(I,J) 302 CONTINUE 301 CONTINUE

DO 3777 1=1,JC 3777 RO(l,I)=l.O

JCA=JC-1 DO 317 I=l,JCA L=l+l DO 317 J=L,JC f<.O( I, J )= PV ( I, J ) / S QP. T ( PV ( I , I ) ,:,py ( J, J) ) RO(J,l)=RC(l,J)

317 CONTINUE NV4=NV(4) f\V3 =NV ( 3) NV2=NV ( 2) NVl=NV ( l) DO 3000 L4=1,NV4 PV(4,4)=FPV(4,4)+ZV(4,L4l*SPV(4 1 4) DO 3100 L3=1,NV3 PV(3,3)=FPV(3,3)+ZV(3,L3)*SPV(3,3J PV(3,4)=R0(3,4J*SQRT(PV(3,3)*PV(4,4J) PV(4,3)=PV(3,4) DO 3200 L2=1,NV2 PV(2,2)=fPV(2,2)+ZV(2,L2)*SPV{2,2) PV(2,3)=RC(2,31*SCRT(PV(2,2)*PV(3,3)) PV(2,4)=RC(2,4)*SORT(PV(2,2)*PV(4,4)) PV(3,2)=PV(2,3) PV(4,2)=PV(2,4) DO 3300 Ll=l,NVl PV(l,l)=FPV(l,l)+ZV(l,Ll)*SPV(l,1) PV( 1,2)=RC(l,2)*SCRT(PV(l,l)*PV(2,2J) PV(l,3)=RO(l,3)*SQRT(PV(l,l)*PV(3,3))

.... .... CX)

Page 126: QUALITY CONTROL OPERATING PROCEDURES FOR

PV(l,4)=RCC1,4)*SQRT(PV(l,l)*PV(4 1 4JJ PY(2,U=PV(l,2) PV( 3, 1) =PV( 1,3) PV(4, U=PV( 1,4) CALL CCf\VER4 l\:M4=NM(4) NM3=NM'3) l':M2=N~( 2) Nt'il=NM(l) CO 4000 f"4=1,NM4 AVE(4)=TRUEAV(4)+ZM(4,M4)*DVE(4) DO 4100 M3=1,NM3 AVE(3)=TRUEAV(3)+Zr(3,M3)*0Vf(3) DO 4200 M2=1,NM2 AVE(2l=TRUEAV(2)+ZM(2,~2)*DVE(2) DO 4300 Ml=l,NMl AVE(l)=TRUEAV(l)+ZM(l,Ml)*DVE(l) OOOC=O. MOOC=O NOOC=O DO 1500 KK=l,MM CALL RANGEN4 CALL MANDV CALL TEST

1500 CON TI NUE AA=NOOC AMOOC=MCOC BB=MM PER=AA*lOO.C/88 APE~=lOO.O*AMOOC/BB OPER=lOO.O*COOC/8B ID( U=ZV(4,L4)

_, _, \0

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4300 4200 4100 4000 3300 3200 3100 3300

ID(2)=ZV(3,L3) ID(3)=ZV(2,L2) ID( 4)=ZV( l,LU I D ( 5 ) = Z ( 4 , ~4 ) ID(6)=ZM(3,M3) IO( 7)=Z,..<2,M2) ID(8)=Z~<l,MU ID(9)=OPER ID( 10 )=APER ID(ll)=PER hRITE (6,352) (I0(I),1=1,11) PUNCH 3 5 2 , I D ( 1 ) , I D ( 2 ) , ID ( 3 ) , ID ( 4 ) , ID { 5 ) , I D ( 6) , ID ( 7 ) , I D ( 8 ) , l D ( 9) ,

XID(l0),10(11) CONTINUE CJNT INUE CONTINUE CONTINUE CONTINUE CONTINUE CONTINUE CUNTit\UE STOP END

__, N 0

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Appendix E

SUBROUTINES

121

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C

C

C

C

C

SUBqOUTINE CCNVER2

C O t-1 :-1 Q N / BL OK M AV E ( 5 ) , X B AR. C 5 ) , S V ( 5 , 5 ) , P V ( 5 , 5 ) , P V I ( 5 , 5 ) , D E V ( 5 ) , XGREAT(5),SMALL(5),X(50,5),T~UEAV(S),FPV(5,5)

COMMON /BLCKB/ DPV,NOOC,IX,DtCC,MOOC,IR,R,JC,C,DPVL COM~ON /BLCKC/ A(5,5)

A(l,l)=SQkT(PV(l,1)) A(2,l)=PV(2,1)/A(l,1) A(l,2)=0. A(2,2)=SQRT(PV(2,2)-A(2,1)**2) RETURN ENO

SUBROUTINE RANGEN2

COM ~ON / 8 LOK A/ AVE ( 5 ) , X B r.q ( 5 ) , S V ( 5, 5) , PV ( 5 , 5) , P VI ( 5, 5) , DEV ( 5) , X GREAT ( 5) , S ~ALL ( 5 ) , X ( 5 O, 5) , TRUE AV ( 5) , F PV ( 5, S)

COMMON /BLCKB/ DPV,f'..:OOC,IX,DOCC,r1ccc,1R,R,JC,C,DPVL CJ~MON /5LOKC/ A(5,5) OP1ENSICN WC5,5) DO 10 I=l,IR DO 350 J=l,2 CALL GAUSS (IX,1.0,0.0,V) W(l,J)=V

350 CONTINUE 10 CONTINUE

DO 300 1=1, IR X ( I , 1 ) = A ( 1 , 1 ) ~,w ( I , 1 ) + A ( 1, 2) * \·! ( I, 2 ) +AVE ( 1) X(I,2)=A(2,l)*W(l,l)+A(2,2)*W(I,2)+AVEC2)

300 CONTINUE

_, N N

Page 130: QUALITY CONTROL OPERATING PROCEDURES FOR

C

C

C

C

RETURN END

SUBROUTINE CONV~R4

COMXON /BLCKA/ AVE(5),XBAR(~),SV(5,5),PV(5,5),PVl(S,5),DEV(5), XGREAT(5),SMALL(5),X(50,5),TRUEAV(5),FPV{5,5)

CO~MQN /BLCK6/ DPV,NOOC,IX,DOCC,PCOC,IR,R,JC,C,DPVL COMMON /BLOKC/ A(5,5) A(l,l)=SQKT(PV(l,1)) A(2,l)=PV(2,l)/A{l,1) A(3,l)=PV(3,1)/A(l,1) J(4,l)=PV(4,1)/A(l,1) A(2,2J=SQRT(PV(2,2)-A(2,1)**2) A(3,2)=(PV(3,2)-A(3,l)*A(2,1))/A(2,2) A{3,3J=SQRT(PV(3,3)-A(3,1)**2-A(3,2)**2) A{4,2)=(PV(4,2)-A(4,l)*A(2,1))/A(2,2) A(4,3)=(PV(4,3)-A(4,l)*A(3,1)-A(4,2)*A(3,2))/A(3,3) AC4,4)=SQRT(PV(4,4)-A(4,1)**2-A(4,2)**2-AC4,3)**2) A(l,2)=0.0 A(l,3)=0.0 A(l,4)=0.0 A(2,3)=0.0 A{2,4)=0.0 A(3,4)=0.0 RETURN E~

SU~RGUTINE RANGEN4

COM~ON /BLOKA/ AVE(5),XBAR(S),SV(5,5),PV(5,5),PVI(5,5),DEV(5), XCREAT(5),SMALL(5),X(50,5),TRUEAV(S),FPVC5,5)

..... N w

Page 131: QUALITY CONTROL OPERATING PROCEDURES FOR

350

200

205 10

C

C

COMMON /BLOKB/ DPV,NOOC,IX,DCOC,~OOC,IR,R,JC,C,DPVL COMMO~ /BLCKC/ A(5,5) 0 !:''IE r~ SI ON h ( 5 0) DO 10 1=1, IR DO 350 J=l,JC CALL GAUSS (IX,1.0,0.0,V) W(J)=V CONTlf\UE DO 205 L=l,JC X (I, L )= 0. 0 DO 200 K=l,JC Xll,L)=X(l,L)+A(L,K)*W(K) CONTINUE X(I ,L)=X(I,U+AVE(L) CONTINUE CONTlf\UE RETURN END

SUBROUTINE MANDY

COMMON /BLCKA/ AVE(5),XBA~(5},SV(5,5),PVC5,SJ,PVl(5,5),DEV(5), XGREAT(5),SMALL(5),X(50,5),TRUEAV(5),FPV(5,5)

COMMON /BLCK8/ DPV,NOOC,IX,DCGC,MCCC,IR,R,JC,C,DPVL COMMON /BLOKC/ CHIONE,CHIK,DSV COMMON /BLCKH/ SS(l0,10),TOT(lO) DO 55 1=1,JC TOT ( I )=O.

55 SS(l,l)=O. DO 60 I=l,JC l=l+l DO 60 J=L,JC

N .i:.

Page 132: QUALITY CONTROL OPERATING PROCEDURES FOR

60

70

85 83 80

90

110 100

122

C

SS(l,J)=O. DO 70 J= 1,JC 00 70 1=1,IR TOT ( J) = X ( I , J) + TOT ( J) SS(J,J)=SS(J,J)+X(I,J)**2 JCA=JC-1 DO 80 J=l,JCA L=J+l DO 83 K=L,JC DO 85 I=l, IR SS(J,K)=SS(J,K)+X(I,J>*X(l,K) C 01\ITI NUE CONTINUE DD 90 J=l,JC XBAR(J)=TOT(J)/R SV(J,J)=(SS(J,J)-TGT(J)**2/R)/(R-l.O) DO 100 J=l,JCA L=J+l DO 110 K=L,JC SV(J,K)=(SS(J,K)-TOT(J)*TGT(K)/R)/(R-1.0) CONTINUE CONTINUE DO 122 J=l,JCA l=J +l DO 122 K=L,JC SS(K,J)=SS(J,K) SV(K,J)=SV(J,K) RETUR~ END

SUB ROUT I NE CETER

__, N> <.Tl

Page 133: QUALITY CONTROL OPERATING PROCEDURES FOR

C CO~MON /BLOKA/ AVE(5),XBAR(5),SV(5,5),PV(5,5),PVI(5,5),DEV(5),

XGREAT(5),SMALL(5),X(50,5),TPUEAV(5),FPV(5,5) CU~MON /OLOKB/ DPV,NOOC,IX,DCCC,MCOC,IP,R,JC,C,OPVL COM~O~ /eLOKG/ DET K=JC JCA=JC-1 DO 2001 1=1,JCA L=I +l DO 2001 J=L,JC

2001 PV(J,I)=PV(l,J) DO 7 M=2,K DO 7 I=M,K ~=PV(I,M-1)/PV(M-I,M-l) DO 7 J=M,K

7 PV(I,J)=PV(I,J)-PV(M-1,J)*W DET=l.O DO 8 I=l,K

8 CET=DET*PV(I,I) RETURN END

C SUBROUTINE TEST

C

C C C

COMMON /BLGKA/ AVE(5),XBAR(5),SV(5,5),PV(5,5),PVl(5,5),DEV(5), XGREAT(5),S~ALL(5),X(50,5),TRUEAV(5),FPV(5,5)

COMMON /BLOKS/ DPV,NOOC,IX,DOCC,~CCC,IR,R,JC,C,DPVL COMMON /BLOKD/ CHICNE,CHIK,DSV DIMENSION F(5),Z(5),TRS(5,5),WEIG(5)

MGNITORl~G OF THE DISPERSION

...... N O'I

Page 134: QUALITY CONTROL OPERATING PROCEDURES FOR

170 180 200

?10

C

TR-=O. FIR=0. S EC=0. TW=0. CALL CETER CSV=DET DO 20C I=l,JC DO 18 0 J = l , JC TRS(I,J)=O. DO 170 K=l,JC TRS{I ,J)=TRS( I,J) +SV( I ,K)*PVI (K,J) CONTINUE CON TI NL: E CONTINUE DO 210 J=l,JC TR=TR+TRS(J,J) CONTINUE DSVL= ALOG ( DSV) STAT=R*{DPVL-OSVL-C+TR) IF (STAT .GE. CHIK) DOOC=DOOC+l.

C MCNITCRING Of lHE CENTRAL TE~DE~CY C 260 DO 370 J=l,JC

Z(J)=XBAR(J}-T~UEAV(J) IF (XBAP(J) .GE. TRUEAV(J)) GC TO 350 WEIG(J)=S~ALL(J} GO TO 360

350 WEIG(J)=GREAT(J) 360 TW=TW+WEIG(J) 370 CONTINUE 390 CRIT=CHIONE*(C+TW)

...... N ......,

Page 135: QUALITY CONTROL OPERATING PROCEDURES FOR

DO 410 I= 1, JC F(l)=O. DO 40C J=l,JC

400 F(l)=Z(J)*PVI<J,I)+F(I) 410 CONTINUE

DO 420 J=l,JC FIR=FIR+F{J)*Z(J) SEC=SEC+R*WEIG(J)*Z(Jl**2/FPV(J,J)

420 CON TI NUE FIR=FIR*R S T=FI R+S EC IF (ST .GT. CRIT) tl.OCC=MOOC+l

C C TOTAL ~UM3ER OUT CF CO~TROL C

440

C

C

IF ((ST .GT. CRIT) .OR. (STAT .GT. CHI3)) NOOC=NOOC+l RETURN ENO

SUBROUTI~E GAUSS(IX,S,AM,V)

A=O.O DO 50 1=1,12 CALL RANDU(IX,IY,Y) IX=IY

50 A=A+Y

C

C

V=( A-6.C)*S+AM RETURN END

SUBROUTINE RANDU(IX,IY,YFL)

..... N CP

Page 136: QUALITY CONTROL OPERATING PROCEDURES FOR

IY= IX*65539 IF (IY) 5,6,6

5 IY=IY+21474e3647+1 6 YFL=IY

YFL=YFL*0.4656613E-9 P.ETURN END

.... N

Page 137: QUALITY CONTROL OPERATING PROCEDURES FOR

Appendix F

TWO VARIABLES SIMULATION RESULTS

130

Page 138: QUALITY CONTROL OPERATING PROCEDURES FOR

131

(1) Correlation Coefficient= Standard Value

Page 139: QUALITY CONTROL OPERATING PROCEDURES FOR

S.D. AwAY FROM STANDARD PROCESS DISPERSION MEAN TOTAL

VARIANCE CENTRAL TENDENCY PERCENT PERCENT PERCENT

( 6) ( A ) ( R) (t.) iJ.o.c. n.o.c. o.o.c. 0 0 0 0 0 l l 0 0 0 2 2 22 23 0 0 0 -2 4 6 9 0 C 2 0 l 4 5 0 0 2 2 l 24 24 0 0 2 -2 l 93 93 0 0 -2 0 2 22 24 0 0 -2 2 1 60 60 0 0 -2 -2 l 31 31 .....

w 0 2 0 0 ~5 6 29 N

0 2 0 2 20 36 47 0 2 0 -2 24 19 39 0 2 2 0 18 6 24 0 2 2 2 38 20 51 0 2 2 -2 28 84 36 0 2 -2 0 zc; 19 43 () 2 -2 2 29 53 67 0 2 -2 -2 ll: 23 35 0 -2 0 C 52 0 52 0 -2 0 2 54 13 62 0 -2 0 -2 52 6 57 0 -2 2 0 50 3 51 0 -2 2 2 47 17 56 0 -2 2 -2 52 85 92 0 -2 -2 0 50 22 63 0 -2 -2 2 47 40 69

Page 140: QUALITY CONTROL OPERATING PROCEDURES FOR

0 -2 -2 -2 57 21 70 2 G 0 0 16 4 19 2 0 0 2 11 18 28 2 C 0 -2 16 9 23 2 0 2 0 15 8 20 2 0 ? 2 q 33 40 .... 2 0 2 -2 lP 78 82 2 0 -2 0 12 24 32 2 0 -2 2 q 58 63 2 0 -2 -2 20 36 51 2 2 0 0 33 6 34 2 2 0 2 19 20 36 2 2 0 -2 25 10 34 2 2 2 0 14 9 22 2 2 2 2 ")";)

L..., 36 54 2 2 2 -2 20 86 90 ....

w 2 2 -? 0 7 .... 17 35 w -~ 2 2 -2 2 23 60 67 2 2 -2 -2 ?8 26 46 2 -2 0 0 8 <; 5 90 2 -2 0 2 31 16 82 2 -2 0 -2 3f 9 37 2 -2 2 0 91 3 91 2 -2 2 2 35 18 90 2 -2 2 -2 -~ C,~ 73 95 2 -? -2 0 87 20 88 2 -£ -2 2 81 48 90 2 -2 -2 -2 82 25 86

-2 C 0 0 22 l 23 -2 0 0 2 35 28 54 -2 0 0 -2 26 7 31 -2 0 2 0 22 5 27

Page 141: QUALITY CONTROL OPERATING PROCEDURES FOR

-2 0 2 2 21 27 43 -2 0 2 -2 17 81 35 -2 0 -2 0 29 13 36 -2 0 -2 2 34 38 53 -2 0 -2 -2 23 27 43 -2 2 0 0 O] 3 91 -2 2 0 2 87 29 90 -2 2 0 -2 88 13 38 -2 2 2 0 90 8 90 -2 2 2 2 94 26 96 -2 2 2 -2 ::.7 73 94 -2 2 -2 0 so 12 90 -2 2 -2 2 86 53 93 -2 2 -2 -2 95 37 9€ -2 -2 0 0 45 0 45 -w -2 -2 0 2 50 9 54 -2 -2 0 -2 37 3 40 -2 -2 2 0 41 l 42 -2 -2 2 2 45 12 54 -2 -2 2 -2 47 85 94 -? ... -2 0 43 7 47 -L

-2 -2 -2 2 60 41 75 -2 -2 -2 -2 53 23 66

Page 142: QUALITY CONTROL OPERATING PROCEDURES FOR

135

(2) Correlation Coefficient= Standard Value x 0.8

Page 143: QUALITY CONTROL OPERATING PROCEDURES FOR

S.D. AWAY FROM STANDARD PROCESS DISPERSION MEAN TOTAL

VAR IANCF CENTRAL TENDENCY PE:RC ENT PER CENT PERCENT ( B) (A) ( f:'., ) ( A} C.l;.C. r1.-J.C. o.r.c.

0 0 0 0 2 l 3 0 0 0 2 l 27 28 0 0 0 -2 3 12 14 0 0 2 0 0 6 6 0 0 2 2 " 18 23 _, 0 0 2 -2 2 89 89 0 0 -2 0 1 23 23 0 0 -2 2 4 44 46 0 0 -2 -2 2 28 30 .....

w 0 2 0 0 1~ 5 23 °' 0 2 0 2 29 27 52 0 2 0 -2 JG 19 43 0 2 2 0 26 6 30 0 2 2 -; zc, 36 61 L..

0 2 2 -? 25 37 92 0 ? -2 0 24 17 37 0 2 -? 2 35 52 67 0 2 -2 -2 18 36 50 0 -2 0 0 4f l 49 0 -2 0 2 51 8 55 0 -2 0 -2 54 0 54 0 -2 2 0 55 2 57 0 -2 2 2 55 24 68 0 -2 2 -2 50 86 92 0 -2 -?. 0 50 22 62 0 -2 -2 2 55 41 75

Page 144: QUALITY CONTROL OPERATING PROCEDURES FOR

0 -2 -2 -2 5e 22 67 2 0 0 0 11 4 14 2 0 0 2 lt 24 37 2 0 0 -2 7 12 17 2 0 2 0 11 3 14 2 0 2 2 11 26 34 2 0 2 -2 10 86 86 2 0 -2 0 9 23 31 2 0 -2 2 E 53 59 2 C -2 -2 7 30 35 2 2 0 0 22 3 23 2 2 0 2 22 30 46 2 2 0 -2 27 21 40 2 2 2 0 24 5 29 2 2 2 2 18 33 43 2 2 2 -2 18 88 <JO

_, w

2 2 -2 0 lS 25 36 -..J

2 2 -2 2 ? r, ,_ 1,; 61 6<; 2 2 -2 -2 26 31 50 2 -2 0 0 C"=> _,_, 1 93 2 -2 0 2 86 17 88 2 -2 0 -2 79 7 81 2 -2 2 0 89 5 91 2 -2 2 2 C/2 28 94 2 -2 2 -2 gc J. 78 97 2 -2 -2 0 89 19 91 2 -2 -2 2 86 47 95 2 -2 -2 -2 85 32 90

-2 0 0 0 32 0 32 _, 0 0 2 21 24 40 '-

-2 0 0 -2 25 8 31 -2 0 2 0 23 1 24

Page 145: QUALITY CONTROL OPERATING PROCEDURES FOR

-2 (' 2 2 29 25 50 -2 (' 2 -2 21 87 88 -2 0 -2 0 29 13 31 -2 0 -2 2 20 44 56 -2 r, -2 -2 30 22 47 I.,

-2 2 0 0 93 4 93 -2 2 0 2 95 26 98 -2 2 0 -2 g4 8 88 -2 2 2 0 g<; l 90 -2 2 2 2 oo 25 92 -2 2 2 -2 q~ .L 73 97 -2 2 -2 0 so 18 90 -2 2 -2 2 93 50 99 -2 2 -2 -2 £5 25 89 -2 -2 0 0 37 0 37 .....

w -2 -2 0 2 41 11 49 CX)

-2 -2 0 -2 35 2 36 -z -2 2 0 53 0 53 -2 -2 2 2 42 18 56 -2 -2 2 -2 44- 91 97 -2 -2 -2 C, 47 11 54 -2 -2 -2 2 47 24 60 -2 -2 -2 -2 4C 21 52

Page 146: QUALITY CONTROL OPERATING PROCEDURES FOR

139

(3) Correlation Coefficient= Standard Value x l .1

Page 147: QUALITY CONTROL OPERATING PROCEDURES FOR

S.D. AAAY FROM STA~OARD P~OCESS QISPEPSYDN MEAN TOT /\L

VAR I A":cr CENTRAL Tf~.;CENCY P rncu:r P [KC ENT PF.l?CHH

( 5) ( A J ( fl ) { /'. ) {' • r; • C • ri.ci.c. o.o.c. 0 0 0 0 0 4 4 0 0 0 2 2 15 17 0 0 0 -2 5 9 14 0 0 2 0 l 3 4 J 0 2 2 4 35 37 0 0 2 -2 0 87 87 0 C -2 0 5 8 13 0 0 -2 2 l 56 57 0 0 -2 -2 3 29 31 .....

.i:. 0 2 0 0 29 4 31 0

0 2 0 2 30 29 52 0 2 0 -2 25 19 37 a 2 2 0 30 5 32 0 2 2 2 27 31 45 0 ? 2 -2 27 34 87 0 2 -2 0 26 22 42 0 2 -2 2 21 59 69 0 2 -2 -2 29 29 49 0 -2 0 0 50 l 50 0 -2 0 2 64 9 67 0 -2 0 -2 ?3 4 56 0 -2 2 0 53 4 55 0 -2 2 2 53 24 66 0 -2 2 -2 49 85 92 0 -2 -2 0 57 15 63 0 ..., -2 2 48 41 69 -L

Page 148: QUALITY CONTROL OPERATING PROCEDURES FOR

0 -2 -2 -2 55 31 71 2 0 0 0 13 4 17 2 (; 0 2 10 24 33 2 0 0 -2 12 10 21 2 0 2 0 7 9 16 2 0 2 2 14 23 35 2 0 2 -2 10 87 88 2 0 -2 0 14 21 35 2 C -2 2 12 63 68 2 0 -2 -2 22 23 39 2 2 0 0 2 fl 4 30 2 2 0 2 23 30 40 2 2 0 -2 lo 14 26 2 2 2 0 19 8 24 2 2 2 2 18 25 39 2 2 2 -2 33 38 92

__,

2 2 -2 0 25 19 39 __,

2 2 -2 2 25 56 68 2 2 -2 -2 27 38 58 2 -2 0 C 9(• l 91 2 -2 0 2 83 13 86 2 -2 0 -2 84 8 87 2 -? 2 0 32 7 84 <-

2 -2 2 2 81 24 S6 2 -2 2 -2 32 69 94 2 -2 -2 0 39 26 93 2 -2 -2 2 87 46 94 2 -2 -2 -2 88 27 92

-2 0 0 0 26 C 26 -2 0 a 2 30 27 48 -2 f", 0 -2 33 7 39 V

-2 0 2 0 19 2 21

Page 149: QUALITY CONTROL OPERATING PROCEDURES FOR

-2 0 2 2 28 27 48 -2 0 2 -2 35 81 84 -2 0 -2 0 JS 11 41 -2 0 -2 2 33 47 67 -2 0 -2 -2 26 26 1t3 -2 2 0 0 10 3 90 -2 2 0 2 92 22 93 -2 2 0 -2 93 16 94 -2 2 2 0 93 5 93 -2 2 2 2 86 31 91 -2 2 2 -2 93 71 99 -2 2 -2 0 Gl 12 92 -2 2 -2 2 87 43 92 -2 2 -2 -2 89 25 91 -2 - ? 0 0 49 0 49

_, ... -2 -2 0 2 51 9 55 I'\)

-2 -2 0 -2 45 0 45 -2 -2 2 0 3c; 2 40 -2 -2 2 2 51 18 62 -2 -2 2 -2 50 i35 q 1 -2 -2 -2 C 43 12 51 -2 -z -2 2 47 35 67 -2 -2 -7 -2 4B 20 59

Page 150: QUALITY CONTROL OPERATING PROCEDURES FOR

Appendix G

FOUR VARIABLES SIMULATION RESULTS

143

Page 151: QUALITY CONTROL OPERATING PROCEDURES FOR

144

(1) Correlation Coefficients= Standard Values

and All Variances= Standard Values

Page 152: QUALITY CONTROL OPERATING PROCEDURES FOR

S.D. AWAY FROM STANDARD PROCESS DISPERSION MEAN TOTAL VARIANCE CENTRAL TENDE~CY PERCENT PER CENT PERCENT

( D) (C) ( B ) (A) ( D) ( C) ( B ) (A) o.o.c. o.o.c. o.o •. c. 0 u 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 2 1 1 2 0 0 0 0 0 0 0 -2 3 1 4 0 0 0 0 0 0 2 0 3 1 4 0 0 0 0 0 0 2 2 2 1 3 0 0 0 0 0 0 2 -2 2 18 20 a 0 0 0 0 0 -2 0 2 0 2 0 0 0 0 0 0 -2 2 2 12 14 0 0 0 0 0 0 -2 -2 1 9 10 0 0 0 0 0 2 0 0 1 3 4 0 0 0 0 0 2 0 2 3 9 12 _, 0 0 0 0 0 2 0 -2 0 15 15 .,1::1,

U"I 0 0 0 0 0 2 2 0 4 13 16 0 0 0 0 0 2 2 2 3 11 14 0 0 0 0 0 2 2 -2 2 36 37 0 0 0 0 0 2 -2 0 2 11 13 0 0 0 0 0 2 -2 2 0 24 24 0 0 0 0 0 2 -2 -2 4 24 27 0 0 0 0 0 -2 0 0 2 1 3 0 0 0 0 0 -2 0 2 5 6 11 0 0 0 0 0 -2 0 -2 3 10 13 0 0 0 0 0 -2 2 0 4 4 7 0 0 0 0 0 -2 2 2 2 20 22 0 0 0 0 0 -2 2 -2 7 34 40 0 0 0 0 0 -2 -2 0 2 5 7 0 0 0 0 0 -2 -2 2 0 60 60 0 0 0 0 0 ...a.2 -2 -2 1 13 14

Page 153: QUALITY CONTROL OPERATING PROCEDURES FOR

0 0 0 0 2 0 0 0 4 2 6 0 0 0 0 2 0 0 2 5 4 9 0 0 0 0 2 0 0 -2 4 7 10 0 0 0 0 2 0 2 0 4 6 10 0 0 0 0 2 0 2 2 3 11 14 . 0 0 0 0 2 0 2 -2 2 21 22 C a 0 0 2 G -2 C 6 3 8 0 0 0 0 2 0 -2 2 5 25 29 :) 0 0 0 2 0 -2 -2 2 10 11 0 0 0 0 2 2 0 0 3 1 10 0 0 0 0 2 2 0 2 0 14 14 0 0 0 0 2 2 0 -2 0 29 29 0 0 0 0 2 2 2 0 l 24 25 0 0 0 0 2 2 2 2 1 30 31 a 0 0 0 2 2 2 -2 2 62 62 0 0 0 0 2 2 -2 0 1 15 16 0 0 0 0 2 2 -2 2 1 37 38 ..... 0 0 0 0 2 2 -2 -2 3 32 34 .:::a

O'I

0 0 0 0 2 -2 0 0 5 5 9 0 0 0 0 2 -2 0 2 5 16 21 0 0 0 0 2 -2 0 -2 2 14 16 0 0 0 0 2 -2 2 0 4 20 23 0 0 0 0 2 -2 2 2 2 17 19 0 0 0 0 2 -2 2 -2 2 44 45 0 0 0 0 2 -2 -2 0 3 16 19 0 0 0 0 2 -2 -2 2 1 65 65 0 0 0 0 2 -2 -2 -2 3 26 28 0 0 0 0 -2 0 0 0 3 0 3 0 0 0 0 -2 0 0 2 l 4 5 0 0 0 0 -2 0 0 -2 2 7 9 0 0 0 0 -2 0 2 0 2 2 4 0 0 0 0 -2 0 2 2 3 5 8

Page 154: QUALITY CONTROL OPERATING PROCEDURES FOR

0 0 0 0 -2 0 2 -2 5 21 24 C 0 0 0 -2 0 -2 0 3 3 6 0 0 0 0 -2 0 -2 2 3 36 38 G 0 0 0 -2 0 -2 -2 1 14 15 0 0 0 0 -2 2 0 0 1 8 8 0 0 0 0 -2 2 0 2 2 14 16 0 0 0 0 -2 2 0 -2 3 19 20 0 0 0 0 -2 2 2 0 1 22 23 C 0 0 0 -2 2 2 2 4 22 24 0 0 0 0 -2 2 2 -2 5 50 54 0 0 0 0 -2 2 -2 0 0 17 17 0 0 0 0 -2 2 -2 2 4 41 44 0 0 0 0 -2 2 -2 -2 1 23 24 ,.. 0 0 0 -2 -2 0 0 4 2 6 I.,

0 0 0 0 -2 -2 0 2 6 34 39 0 0 0 0 -2 -2 0 -2 0 14 14 .... 0 0 0 0 -2 -2 2 0 5 16 21 " 0 0 0 0 -2 -2 2 2 3 42 45 0 0 0 0 -2 -2 2 -2 4 35 37 0 0 0 0 -2 -2 -2 0 0 10 10 0 0 0 0 -2 -2 -2 2 1 88 88 a 0 0 0 .-2 -2. -2 -;2 3 16 18

Page 155: QUALITY CONTROL OPERATING PROCEDURES FOR

148

(2) Correlation Coefficients= Standard Values

and All Means= Standard Values

Page 156: QUALITY CONTROL OPERATING PROCEDURES FOR

S.D. AWAY FROM STANDARD PROCESS DI SP ER SION MEAN TOTAL

VARIANCE CENTPAL TENDENCY PERCENT PERCENT PERCENT

( D ) (C) (B) ( A ) (0) (C) ( B) ( A ) 0 .o .c. o.o.c. o.o.c. 0 0 0 0 0 0 0 0 1 0 1 0 0 0 2 0 0 0 0 8 1 9 0 0 0 -2 0 0 0 0 8 0 8 0 0 2 0 0 0 0 0 10 0 10 0 0 2 2 0 0 0 0 13 0 13 0 0 2 -2 0 0 0 0 26 0 26 0 0 -2 0 0 0 0 0 14 0 14 0 0 -2 2 0 0 0 0 37 0 31 0 0 -2 -2 0 0 0 0 21 0 21 0 2 0 0 0 0 0 0 3 1 4 ..... 0 2 0 2 0 0 0 0 13 0 13 \0 0 2 0 -2 0 0 0 0 19 1 20 0 2 2 0 0 0 0 0 17 0 17 0 2 2 2 0 0 0 0 19 2 21 0 2 2 -2 0 0 0 0 37 0 37 r) 2 -2 0 0 0 0 0 19 0 19 0 2 -2 2 0 0 0 0 30 1 31 0 2 -2 -2 0 0 0 0 36 0 36 0 -2 0 0 0 0 0 0 7 1 8 0 -2 0 2 0 0 0 0 18 0 18 0 -2 0 -2 0 0 0 0 11 0 11 0 -2 2 0 0 0 0 0 13 0 13 0 -2 2 2 0 0 0 0 21 0 21 0 -2 2 -2 0 0 0 0 31 0 31 0 -2 -2 0 0 0 0 0 30 0 30 0 -2 -2 2 0 0 0 0 46 0 46

Page 157: QUALITY CONTROL OPERATING PROCEDURES FOR

0 -2 -2 -2 0 0 0 0 23 0 23 2 0 0 0 0 0 0 0 9 0 9 2 0 0 2 0 0 0 0 8 0 8 2 0 0 -2 0 0 0 0 21 l 22 2 0 2 0 0 0 0 0 17 0 17 2 0 2 2 0 0 0 0 22 1 23 2 0 2 -2 0 0 0 0 56 0 56 2 0 -2 ,.. 0 0 0 0 32 0 32 V

2 0 -2 2 0 0 0 0 45 0 45 2 a -2 -2 0 C 0 0 30 0 30 2 2 0 0 0 0 0 0 9 0 9 2 2 0 2 0 0 0 0 13 1 14 2 2 0 -2 0 0 0 0 34 0 34 2 2 2 0 0 0 C 0 21 0 21 2 2 2 2 0 0 0 0 25 0 25 2 2 2 -2 0 0 0 0 46 1 46 2 2 -2 0 0 0 0 0 35 0 35 ...... 2 2 -2 2 0 0 0 0 44 0 44 u,

0 2 2 -2 -2 0 0 0 0 50 l 51 2 -2 0 0 0 0 0 0 10 0 10 2 -2 0 2 0 0 0 0 16 0 16 2 -2 0 -2 0 0 0 0 26 0 26 2 -2 2 C 0 0 0 0 22 l 23 2 -2 2 2 0 0 0 0 21 0 21 2 -2 2 -2 0 0 0 0 49 0 49 '2. -2 -2 0 0 0 0 0 30 0 30 2 -2 -2 2 0 0 0 0 53 0 53 2 -2 -2 -2 0 0 0 0 37 0 37

-2 0 0 0 0 0 0 0 6 0 6 -2 0 0 2 0 0 0 0 26 0 26 -2 0 0 -2 0 0 0 0 21 0 21 -2 0 2 0 0 0 0 0 18 0 18

Page 158: QUALITY CONTROL OPERATING PROCEDURES FOR

-2 0 2 2 0 0 0 0 27 0 21 -2 0 2 -2 0 0 0 0 44 0 44 -2 0 -2 0 0 0 0 0 33 0 33 -2 0 -2 2 0 0 0 0 60 0 60 -2 0 -2 -2 0 0 0 0 36 0 36 -2 2 0 0 0 0 0 0 19 0 19 -2 2 0 2 0 0 0 0 38 0 38 -2 2 a -2 0 0 0 0 30 0 30 -2 2 2 0 0 0 0 0 23 0 23 -2 2 2 2 0 0 0 0 33 0 33 -2 2 2 -2 0 0 0 0 51 0 51 -2 2 -2 0 0 0 0 0 38 0 38 -2 2 -2 2 0 0 0 0 56 0 56 -2 2 -2 -2 0 0 0 0 43 0 43 -2 -2 0 0 0 0 0 0 19 0 19 -2 -2 0 2 0 0 0 0 41 0 41 .... -2 -2 0 -2 0 0 0 0 25 0 25 U'I .... -2 -2 2 0 0 0 0 0 38 0 38 -2 -2 2 2 0 0 0 0 44 1 44 -2 -2 2 -2 0 0 0 0 50 0 50 -2 -2 -2 0 0 0 0 0 49 0 49 -2 -2 -2 2 0 0 0 0 65 0 65 -2 -2 -2 -2 0 0 ,0 0 38 0 38

Page 159: QUALITY CONTROL OPERATING PROCEDURES FOR

QUALITY CONTROL OPERATING PROCEDURES FOR

MULTIPLE QUALITY CHARACTERISTICS AND WEIGHTING FACTORS

by

Peter S. Hsing

(ABSTRACT)

This research is devoted to the development of a procedure for

manufacturing use that applies to cases involving a manufactured item

having more than one quality characteristic and continuous measurements

of these characteristics. There are two phases in this procedure.

The first phase consists of testing the stability of the manufacturing

process with respect to dispersion and central tendency. Once the

stability of the process has been established, maintain the process

within the established bounds of dispersion and central tendency becomes

important. The second phase consists of monitoring dispersion and

central tendency of the current manufacturing process. During the

monitoring central tendency activity, the user is allowed to assign

different weights to the sample mean value both above and below the

standard value. For both dispersion and central tendency monitoring

activities, a method is provided to identify quality characteristics or

the interaction between quality characteristics as the cause of the

trouble when the sampling indicated a lack of control.

An example of the antidiarrheal tablet manufacturing process was

presented to illustrate how to test the stability of the manufacturing

process and how to monitor the current manufacturing process. Step-by-step

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computational procedures and Fortran computer programs were presented.

The cases for dispersion and central tendency deviated from the standard

values were simulated and the results were presented.