putting the patient at the center of healthcare research towards a more inclusive model

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PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

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Page 1: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

PUTTING THE

PATIENT

AT THE

CENTER OF

HEALTHCARE

RESEARCH

Towards a

more inclusive

model

Page 2: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 2

Information of December 31st 2013

OUR GROUP

SANOFI AT A GLANCE

We are a global healthcare company engaged in the research, development, manufacturing and marketing of healthcare solutions. present

in more than

100 countries

more than

110 000employees

Acomprehensive

offer of pharmaceuticals,

vaccines and innovativetherapeutic solutions

112 Industrial sitesin 41 countries

R&D A major biopharmacy

player

• 45% of revenues generated by biologics

• 80% of development projects are biologics

€33 bn*

In sales in 2013

* €32,951 M

Page 3: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

• Multiple Sclerosis• Diabetes• Oncology• Rare Diseases• Cardio-Metabolic Diseases• Immunology• Vaccines• Animal Health

CONFERENCE OF MONTREAL 2014 3

We act as one to discover and develop therapies that prevent, treat and cure disease.

9 projects and vaccines in clinical development*

high potential projects in late stage development*

49

SANOFI R&D

ACCELERATE INNOVATION FOR PATIENTS

Our main areas of research include:

*Information provided as of February 6th, 2014

Page 4: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 4

OUR RESPONSIBILITY

CHANGE THE R&D INNOVATION MODEL

The classic INNOVATION model

Belief that advances in basic sciences can be easily translated to human disease

A linear process from discovery to development to market with little interactions throughout the innovation cycle

Focus on novel (but not necessarily validated) targets in humans

A strategy of “Many Shots on Goal”

A non-linear process that takes into account provider, purchaser and user metrics including pipeline activity, clinical success, regulatory approval, patient access, satisfaction of unmet need and overall value to society

A greater understanding of human disease

Open innovation and partnership

The new INNOVATION model

Raising the batting

average!

Page 5: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 5

OURPRESIDENT OF R&D

PATIENTS ARE THE MISSING LINK

Page 6: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 6

Increasing public awareness & improving clinical trial educationMAKING

CLINICAL TRIALS PATIENT FRIENDLY

SO WHAT ARE WE DOING ABOUT IT?

What do patients know about clinical research? How do they get their facts?How do they know if a study exists?Do they ever hear the results?

Bringing patients within the project teame.g. Diabetes Patient Advisors input into study designs, innovation & outreach strategies

Innovating to ease patient experiencee-informed consente-technology (e.g. telemetry)Point of care technologies (e.g. Dried Blood Spots)

Page 7: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 7

SO WHAT ARE WE DOING ABOUT IT?

BEFORE AND BEYOND CLINICAL TRIALS

Opportunities exists from target to use

Target identificationPath to proof of conceptEffective valueAccess

Partner in Patient Health (PiPH) initiativeEU-NA PiPH CouncilCollaborate | Innovate Challenge

Newly created position of Chief Patient Officer

Page 8: PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

CONFERENCE OF MONTREAL 2014 8

OUR “RAISON D’ETRE”

ACCELERATE INNOVATION FOR PATIENTS