Purpose of the Interactive Breath-Hold Control System

To improve CT-guided biopsies of the lung or upper abdomen by allowing consistent, optimal visualization of the target lesion throughout procedures where respiratory motion is a problem.

Significance of Respiratory Motion

During normal breathing, lung and upper abdomen lesions can move 1-6 cm in SI direction

DEEPER BREATH

Breath Hold - Assisted Lung Biopsy to Avoid Rib

Nodule accessible through intercostal space

SMALL BREATH

Nodule behind rib

Breath Hold - Assisted CTF Biopsy(Previous unsuccessful biopsy at outside hospital due to motion)

Diagnosis: Metastatic Melanoma

1 cm nodule

Breath Hold-Assisted Biopsy of Lesions in Difficult Locations

9mm Para-Aortic Lung Nodule

Aorta

Potential Applications

• Tumor Ablation• Radiation Therapy Protocols• Robotic Intervention• Intratumoral injections (gene rx)• Fluid Aspiration and Drainage• Chest Imaging (reproducibility)• MRI: Spectroscopy, FUS, MRC• PET/CT• CT perfusion studies

– Solitary Pulmonary Nodule– Liver– Pancreas– Renal

Clinical Benefits

• The Breath Hold is: – Sensitive and reliable for monitoring respiratory levels

and providing patient feedback– Allows optimal visualization of the target lesion

throughout the procedure– Enables procedures to be simpler to perform

• Benefits of the Breath Hold system include:– Statistically significant in CTF exposure time, patient

radiation dose, and needle puncture attempts– Fewer procedure-related complications, particularly a

in pneumothorax rate – needle placement time and total procedure time