psyc550 biological bases of behavior communication and movement
TRANSCRIPT
Speech Production and Comprehension: Brain
Mechanisms• cerebrovascualr accident
– A “stroke”; brain damage caused by occlusion or rupture of a blood vessel in the brain.
• aphasia– Difficulty in producing or comprehending speech
not produced by deafness or a simple motor deficit; caused by brain damage.
• Broca’s aphasia– A form of aphasia characterized by agrammatism,
anomia, and extreme difficulty in speech articulation.
Speech Production and Comprehension: Brain
Mechanisms• function word
– A preposition, article, or other word that conveys little of the meaning of a sentence but is important in specifying its grammatical structure.
• content word– A noun, verb, adjective, or adverb that
conveys meaning.
Speech Production and Comprehension: Brain Mechanisms
• circumlocution– A strategy by which people with anomia find
alternative ways to say something when they are unable to think of the most appropriate word.
• prosody– The use of changes in intonation and
emphasis to convey meaning in speech besides that specified by the particular words; an important means of communication of emotions.
Speech Production and Comprehension: Brain Mechanisms
• Broca’s area– A region of frontal cortex, located just rostral to the base of
the left primary motor cortex, that is necessary for normal speech production.
• agrammatism– One of the usual symptoms of Broca’s aphasia; a difficulty in
comprehending or properly employing grammatical devices, such as verb endings and word order.
• anomia– Difficulty in finding (remembering) the appropriate word to
describe an object, action, or attribute, one of the symptoms of aphasia.
• apraxia of speech– Impairment in the ability to program movements of the
tongue, lips, and throat required to produce the proper sequence of speech sounds.
Speech Production and Comprehension: Brain Mechanisms
• Wernicke’s area– A region of auditory association cortex on
the left temporal lobe of humans, which is important in the comprehension of words and the production of meaningful speech.
• Wernicke’s aphasia– A form of aphasia characterized by poor
speech comprehension and fluent but meaningless speech.
Speech Production and Comprehension: Brain Mechanisms
• pure word deafness– The ability to hear, to speak, and (usually) to
read and write without being able to comprehend the meaning of speech; caused by damage to Wernicke’s area or disruption of auditory inputs to this region.
• transcortical sensory aphasia– A speech disorder in which a person has
difficulty comprehending speech and producing meaningful spontaneous speech but can repeat speech; caused by damage to the brain posterior to Wernicke’s area.
Speech Production and Comprehension: Brain Mechanisms
• autotopagnosia– Inability to name body parts or to identify body
parts that another person names.
• arcuate fasciculus– A bundle of axons that connects Wernicke’s area
with Broca’s area; damage causes conduction aphasia.
• conduction aphasia– An aphasia characterized by inability to repeat
words that are heard but the ability to speak normally and comprehend the speech of others.
Disorders of Reading and
Writing• pure alexia
– Loss of the ability to read without loss of the ability to write; produced by brain damage.
• whole-word reading– Reading by recognizing a word as a whole;
“sight-reading.”
• phonetic reading– Reading by decoding the phonetic
significance of letter strings; “sound reading.”
The Cambridge Pseudohoax
Accoidrng to a rereasch at Cimbradge University, it dosen't mttaer in waht oedrr
the letters in a wrod are. The olny importnat tihng is taht the fsrit and lsat ltteer be in the
rihgt plcae.
The rset can be a toatl mses and you can slitl raed it wothiut prbolem. Tihs is becuase the huamn mnid deos not raed eevry letter by
iteslf, but the wrod as a whloe.
I was able to read that without great
difficulty
Stro
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Dis
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Stro
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25% 25%25%25%1. Strongly Agree2. Agree3. Disagree4. Strongly
Disagree
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Disorders of Reading and
Writing• surface dyslexia
– A reading disorder in which a person can read words phonetically but has difficulty reading irregularly spelled words by the whole-word method.
• phonological dyslexia– A reading disorder in which a person can read familiar
words but has difficulty reading unfamiliar words or pronounceable non-words.
• word-form dyslexia– A disorder in which a person can read a word only after
spelling out the individual letters.• spelling dyslexia
– An alternative name for word-form dyslexia.
Disorders of Reading and
Writing• direct dyslexia– A language disorder caused by brain damage in which
the person can read words aloud without understanding them.
• phonological dysgraphia– A writing disorder in which the person cannot sound out
words or write them phonetically.• orthographic dysgraphia
– A writing disorder in which the person can spell regularly spelled words but not irregularly spelled ones.
• developmental dyslexia– A reading difficulty in a person of normal intelligence
and perceptual ability; of genetic origin or caused by prenatal or perinatal factors.
Control of Movement by the
Brain• somatotopic organization– A topographically organized mapping of parts of the body
that are represented in a particular region of the brain.• supplemental motor area (SMA)
– A region of association motor cortex of the dorsal and dorsomedial frontal lobe, rostral to primary motor cortex.
• premotor cortex– A region of motor cortex of the lateral frontal lobe, rostral
to the primary motor cortex.• mirror neurons
– Neurons located in the ventral premotor cortex and inferior parietal lobule that respond when the individual makes a particular movement or sees another individual making that movement.
Planum Temporale• Planum temporale seems
larger on the right than left• Triangular area in the
Sylvian Fissure smack in the middle of Wernecke’s area
• Important in music and language
• Usually larger on left than right– If MUCH larger on left –
perfect pitch– If larger on right - dyslexia
• Cells that ought not be there seem to have migrated in that area during development (16-24 weeks gestation)
Control of Movement by the
Brain• apraxia– Difficulty in carrying out purposeful
movements, in the absence of paralysis or muscular weakness.
• callosal apraxia– An apraxia of the left hand caused by
damage to the anterior corpus callosum.
• sympathetic apraxia– A movement disorder of the left hand
caused by damage to the left frontal lobe; similar to callosal apraxia.
Control of Movement by the
Brain• left parietal apraxia– An apraxia caused by damage to the left
parietal lobe; characterized by difficulty in producing sequences of movements by verbal request or in imitation of movements made by someone else.
• constructional apraxia– Difficulty in drawing pictures or diagrams
or in making geometrical constructions of elements such as building blocks or sticks; caused by damage to the right parietal lobe.
Control of Movement by the
Brain• caudate nucleus
– A telencephalic nucleus, one of the input nuclei of the basal ganglia; involved with the control of voluntary movement.
• putamen– A telencephalic nucleus; one of the input nuclei of
the basal ganglia; involved with the control of voluntary movement.
• globus pallidus– A telencephalic nucleus; the primary output
nucleus of the basal ganglia; involved with the control of voluntary movement.
Control of Movement by the
Brain• ventral anterior nucleus (of thalamus)
– A thalamic nucleus that receives projections from the basal ganglia and sends projections to the motor cortex.
• ventrolateral nucleus (of thalamus)– A thalamic nucleus that receives
projections from the basal ganglia and sends projections to the motor cortex.
Control of Movement by the Brain
• direct pathway (in basal ganglia)– The pathway that includes the caudate nucleus and
putamen, the external division of the globus pallidus, the subthalamic nucleus, the internal division of the globus pallidus, and the ventral anterior/ventrolateral thalamic nuclei; has an inhibitory effect on movement.
• indirect pathway (in basal ganglia)– The pathway that includes the caudate nucleus and
putamen, the internal division of the globus pallidus, and the ventral anterior/ventrolateral thalamic nuclei; has an excitatory effect on movement.
• Huntington’s disease– A fatal inherited disorder that causes degeneration of the
caudate nucleus and putamen; characterized by uncontrollable jerking movements, writhing movements, and dementia.
Control of Movement by the
Brain• flocculonodular lobe– A region of the cerebellum; involved in control of
postural reflexes.• vermis
– The portion of the cerebellum located at the midline; receives somatosensory information and helps to control the vestibulospinal and reticulospinal tracts through its connections with the fastigial nucleus.
• fastigial nucleus– A deep cerebellar nucleus; involved in the control of
movement by the reticulospinal and vestibulospinal tracts.
• interposed nucleus– A set of deep cerebellar nuclei; involved in the control
of the rubropinal system.
Control of Movement by the Brain
• pontine nucleus– A large nucleus in the pons that serves as an
important source of input to the cerebellum.
• dentate nucleus– A deep cerebellar nucleus; involved in the
control of rapid, skilled movements by the corticospinal and rubrospinal systems.
• mesencephalic locomotor region– A region of the reticular formation of the
midbrain whose stimulation causes alternating movements of the limbs normally seen during locomotion.
A person in your office can read, write, understand what you say, but
cannot repeat what you say. What’s going on?
He
is in
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ffice
He
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...
He
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He
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25% 25%25%25%1. He is in the wrong office
2. He has conduction aphasia
3. He has pure word deafness
4. He transcortical aphasic echolalia 1010
Degeneration of the caudate nucleus and putamen is seen in:
Lef
t par
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l apra
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Const
ruci
tonal
apra
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Huntin
gton’s
dis
ease
Ext
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amid
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isto
...
25% 25%25%25%
1010
1. Left parietal apraxia
2. Construcitonal apraxia
3. Huntington’s disease
4. Extrapyramidal distortion