prrs situation in the region and control initiative, updates and trends · joint fao/oie workshop...

Joint FAO/OIE Workshop on Swine Disease Control in Asia Beijing, PR China, 18-20 November 2014

PRRS situation in the region and control initiative, updates and

trends

Xinyan Zhai

China Animal Disease Control Center

Joint FAO/OIE Workshop on Swine Disease Control in Asia

Main Contents

• PRRS situation in Asia

• PRRS control initiative, updates and trends


Highly-pathogenic PRRS situation in China



From Jan. to May in 2007, 22 provinces took

place HP-PRRS. There are 194 county outbreak,

289 epidemic points, 45858 diseased pigs,

18597 dead pigs, 5778 culled pigs. (June 11,

2007)



The statistic data of HP-PRRSV accidence between 2008 to 2013 in China

Time 2008 2009 2010 2011 2012 2013

Incidence quantity of pigs (head)

7648 8779 6508 1308 0 0

Dead quantity of pigs

(head)2908 3459 1733 230 0 0

Epidemic point number

57 14 10 14 0 0

Data source from

OFFICIAL VETERINARY BULLETIN



HP-PRRSV detecting results from different monitoring sites within 2011 to 2013

Monitoring site

Sample number Positive number (ratio %)

2011 2012 2013 2011 2012 2013

Scale pig farm 58353 59465 63435 648(2.66) 269(0.94) 301(0.11)

Back-yard 20493 12212 10789 190(0.93) 89(0.79) 66(0.69)

Market 5687 4097 6460 128(2.25) 16(0.39) 71(1.10)

Other sources 23687 22525 19760 110(0.46) 111(0.49) 103(0.52)

Total 108220 98299 100444 1076(0.99) 485(0.49) 541(0.54)

Data source from

OFFICIAL VETERINARY BULLETIN


The prevalence of HP-PRRSV in East and Southeast Asia within 2006-2011

Highly-pathogenic PRRS situation in Asia


The distribution of HP-PRRSV occurrence in Viet Nam in 2007

DAH, AUGUST 2007

Trucks stop for

resting and

washing

transported pigs

Pig movement: North → South

Joint FAO/OIE Workshop on Swine Disease Control in Asia11


HP-PRRSV prevalence in Laos from July to Sep. in 2010.


HP-PRRSV occurred

in Tailand and

Myanmarin 2011.


HP-PRRSV occurred in Cambodia from 2007 to 2010.

Livestock movements and pig

densities of Cambodia(Chetra

et al.) (FAO)


The conference on swine health

management in East-Asia and

South-east Asia(held in Viet

Nam on Aug. 21-25, 2012)

Highly-pathogenic PRRS situation in Asia

East-Asia and South-east Asia area is the center of pig industry worldwide.

FMD, CSF, HP-PRRS are the harmful diseases for pigs at present.

ASF is the biggest potential threat to the pig population.

Backward feeding mode and disordered tansportation of pigs and pork

increase the difficulty in controlling swine diseases.


?

HP-PRRSV is still the main disease of affecting the pig industry in the region！


PRRS control initiative, updates and trends

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Sequence identity

is 95.6%~99.8%

within isolated

HP-PRRSV strain

Sequence identity

is 97.2%~99.3%

compared with

HP-PRRSV JXAI

strain

HP-PRRSV

genetic variation


Pathogenicity test of HP-PRRSV isolates

Time Isolated strain

namepassage

Challeng titre(TCID50/mL)

Piglets age（week）

mobility(%)

mortality (%)

2010NVDC-JXA1 5 104.5 10 100 40

10BJ-5 5 104.5 10 100 40

LW1-13 5 104.5 10 100 60

2011NVDC-HuN/2011 5 104.5 10 100 60

NVDC-VN/2011 5 104.5 10 80 20

NVDC-HEB/2011 5 104.5 10 60 0

2012NVDC-SC/2012 5 104.5 10 60 20

NVDC-BJ4/2012 5 104.5 10 60 0

2013

NVDC-JXA1 5 104.5 10 100 60

NVDC-HEB/2013 5 104.5 10 100 40

NVDC-BJ/2013 5 104.5 10 40 0

NVDC-MD/2013 5 104.5 10 60 0



Protective efficacy assessment of HP-PRRSV vaccine to HP-PRRSV strains isolated in 2013


The result of body

temperature of pigs

challenged by

PRRSV NVDC-

HEB/2013 strain

post vaccination of

JXA1-R strain

The result of body

temperature of pigs

challenged by

PRRSV NVDC-

HEB/2013 strain


800000 HP-

PRRSV(JXA1-R strain)

vaccine

300000 HP-

PRRSV(JXA1-R strain)

vaccine


Improve the timely exchange of epidemiologically relevant information

among affected countries in order to revise national control strategies.

Increase risk based surveillance of HP-PRRSV.

Promote the appropriate use of a safe and efficient vaccine matching with

circulating strains as a tool to reduce clinical symptoms.

Enhance tansportation supervision and comprehensive biosecurity measures.

Carry out the purification and elimination of HP-PRRSV at the right time.



Thank you for your

presentation

No. 17, Tiangui Street,

Biomedical industry Base,

Daxing District, Beijing, P.R.C

prrs situation in the region and control initiative, updates and trends · joint fao/oie workshop...

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