prostate cancer bowen staging with parking parking · › the use of 18f-psma pet provides high...

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pacificradiology.com Bowen Centre 99 Churchill Drive, Crofton Downs, Wellington appointments@pacificradiology.com P. 04 978 5500 F. 04 978 5501 Southern Cross Hospital 129 Bealey Ave, Christchurch 8013 petct@pacificradiology.com P. 03 366 5788 F. 03 366 5755 Prostate cancer staging with 18F-PSMA PET-CT at Pacific Radiology The role for PSMA PET imaging in prostate cancer is to help guide appropriate treatment. Recently several studies have shown the great potential of PSMA PET-CT for initial staging, including lymph node staging, and detection of post-treatment disease recurrence, even at very low PSA levels. Pacific Radiology is now pleased to offer this game changing new radiotracer, for use with PET-CT imaging for staging and restaging of prostate cancer patients. PSMA PET-CT imaging is a new test in New Zealand. Cyclotek Pharmaceuticals currently supplies sites in New Zealand with this important PET tracer. The addition of PSMA PET-CT imaging complements the multi-parametric 3T prostate MRI service that is currently available at the Bowen Centre in Wellington and St Georges Christchurch. Prostate cancer staging with 18F-PSMA PET-CT Churchill Drive Johnsonville Parking Parking Karori Entrance Bowen Centre Bowen Hospital Bealey Avenue Caledonian Road Durham Street North Colombo Street Southern Cross Hospital T2 Axial MRI fused with 18F-PSMA PET scan. Demonstrates focal uptake within prostate bed.

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Page 1: Prostate cancer Bowen staging with Parking Parking · › The use of 18F-PSMA PET provides high diagnostic accuracy and is increasingly used as a staging tool in prostate cancer and

pacificradiology.com

Bowen Centre99 Churchill Drive, Crofton Downs, Wellington

[email protected]

P. 04 978 5500

F. 04 978 5501

Southern Cross Hospital129 Bealey Ave, Christchurch 8013

[email protected]

P. 03 366 5788

F. 03 366 5755

Prostate cancer staging with 18F-PSMA PET-CT at Pacific Radiology

The role for PSMA PET imaging in prostate cancer

is to help guide appropriate treatment. Recently

several studies have shown the great potential of

PSMA PET-CT for initial staging, including lymph

node staging, and detection of post-treatment

disease recurrence, even at very low PSA levels.

Pacific Radiology is now pleased to offer this game

changing new radiotracer, for use with PET-CT

imaging for staging and restaging of prostate

cancer patients.

PSMA PET-CT imaging is a new test in New Zealand.

Cyclotek Pharmaceuticals currently supplies sites

in New Zealand with this important PET tracer.

The addition of PSMA PET-CT imaging complements

the multi-parametric 3T prostate MRI service

that is currently available at the Bowen Centre in

Wellington and St Georges Christchurch.

Prostate cancer staging with 18F-PSMA PET-CTChurchill Drive

Johnsonville

Parking Parking

Karori

EntranceBowenCentre

BowenHospital

Bealey Avenue

Cal

ed

on

ian

Ro

ad

Du

rham

Str

ee

t N

ort

h

Co

lom

bo

Str

ee

t

Sh

erb

orn

e S

tre

et

Southern Cross Hospital

T2 Axial MRI fused with 18F-PSMA PET scan. Demonstrates focal uptake within prostate bed.

Page 2: Prostate cancer Bowen staging with Parking Parking · › The use of 18F-PSMA PET provides high diagnostic accuracy and is increasingly used as a staging tool in prostate cancer and

Cases from Pacific Radiology

Advantages of 18F-PSMA PET-CT

› PET-CT imaging with 18F-PSMA can identify prostate cancer (PC) with excellent contrast and a high detection rate even when the level of PSA is low.

› 18F-PSMA PET-CT is excellent for restaging in recurrence/biochemical failure after definitive treatment of prostate cancer

› The use of 18F-PSMA PET provides high diagnostic accuracy and is increasingly used as a staging tool in prostate cancer and in patients with suspicion of recurrent disease.

› PET-CT is a hybrid imaging technique combining functional and anatomical information.

What will the procedure involve?

A PET-CT scan involves an injection, via a vein

in the arm, of a radioactive tracer. After the

injection there is a wait of 90 minutes to two

hours, before the scan takes place.

The scan takes approximately 30 minutes.

During the scan you may need an intravenous

injection of xray contrast. A technologist

will discuss this with you at the time of your

appointment.

Total appointment time is between 3-4 hours.

What preparation is required?

A personalised instruction sheet will be sent

to you with the exact preparation that you will

need for your scan. However, please feel free

to contact us if you have any questions.

What happens if I’m claustrophobic or need sedation?

If you do need mild sedation for the PET-CT

scan, this will be given at the time of the

examination. It is essential you have someone

to drive you home. You will not be able to

operate a machine or drive a car for 12 hours

following sedation.

What are the risks of the scan?

PET-CT procedures are very safe and routine

procedures. Millions of PET-CT scans have been

done around the world without complication.

The radiation dose for the PET-CT scan is

similar to conventional CT scans, but it is

recommended that you keep some distance

from pregnant women and children for

four hours after your injection, until the

radioactivity in your body has subsided.

When will the results be available?

The results of the PET-CT should be with your

referring doctor within one to three working

days, after which you can discuss the results

with your doctor.

References

Dietlein et al. Comparison of 18F-DCFPyl and 68Ga-PSMA-HBED-CC for PSMA-PET Imaiging in Patients with Relapsed Prostate cancer; Mol Imaging Bio, 2016; 17:575-584

18F-PSMA PET-CT scan, axial fused image demonstrating focal uptake in the prostate gland.

18F-PSMA PET-CT scan, axial fused image demonstrating focal uptake in para-aortic lymph node.

18F-PSMA PET-CT scan, axial fused image demonstrating focal uptake in a bony metastases on the right at L5.