proset fermentation 2016/17 catalogue · all about proset fermentation and cell cultivation system...

proSETFermentation

2016/17 Catalogue

www.cleaverscientific.comwww.cleaverscientific.com

Other products available from Cleaver Scientfic...

HORIZONTAL GEL ELECTROPHORESIS

BLOTTING SYSTEMS

GEL DOCUMENTATION

REAGENTS AND CHEMICALS

VERTICAL GEL SYSTEMS

POWER SUPPLIES

GENERAL LAB EQUIPMENT

For more information please contact Cleaver Scientific Ltd

t: +44 (0)1788 565300

[email protected]

VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION I 3

All about proSET Fermentation and Cell Cultivation System

proSET is a product brandunder Cleaver Scientific, devoted to creating a broad product portfolio for fermentation technologies. We focus on offering cell cultivation solution to the life sciences market.

proSET provides acomprehensive and innovativeline of cultivation products designed for different cellculture experiments andapplications. The system isbenchtop scale and has alarge, colour touch-screenpanel with a user-friendlyinterface.

Its distinctive functionsinclude various programmingoperations to control the pumpspeed, pH level, temperature,and more. The proSET Fermentation System is able toconnect to any PC for real-timerecording and control withinthe vessel.

4 I VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION

Who We Are

Founded in 2014, Cleaver Scientific is now established worldwide as a key manufacturer of products for the Life Science market. Beginning with the manufacture of electrophoresis products in 2004, we have over the past years expanded our range to include many of the products used in Molecular biology and other Scientific laboratories.

Our range now includes Electrophoresis and blotting systems, power supplies, gel documentation, cabinets, radiation protection, general laboratory instruments and reagents and chemicals. Much of the growth in our product range has come from creative and innovative product additions, including the development of Real time electrophoresis, part of our Safe series of products and including our patented COMPAC-50™, which we designed and manufactured in conjunction with the University of Leicester.

Cleaver Scientific has a reputation spread across over 130 countries worldwide for manufacturing innovative, high quality products that are easy to use. We are known for taking the ideas and concerns of users of laboratory equipment and incorporating these ideas into our product range.The end result is we provide a product range with features the researcher and their work can benefit from.

All of our products, including our flagship gel electrophoresis systems, are supplied directly from our manufacturing facility in Rugby, the birthplace of Rugby Football, and based within the heart of the United Kingdom; central to all major international road, rail and air transport networks. Each product represents the culmination of the combined creativity, technical and engineering expertise acquired from over 50 years experience by our in-house manufacturing and scientific product development team.In all of these products, our philosophy remains that we are committed to offering the highest quality products with the latest technical innovations to make the researcher’s life that little bit easier, but also more affordable, particularly in these price-sensitive times.

Quality may be a much misused word, but at Cleaver Scientific it defines what we do, by the timely manufacture and supply of products to our customers that not only fulfil their purpose, but will remain durable and free of imperfections for many years to come. Our accredited ISO9001/2008 quality management system and adherence to this ensures that these principles are met.

2016 marks the latest product launch from Cleaver Scientific – ProSet Fermentation Systems

ProSet Fermentation

ProSet is a product brand under Cleaver Scientific, devoted to creating a broad product portfolio for fermentation technologies from Benchtop, through Pilot to Production scale. This range is focused on offering a complete cell cultivation solution to the life science and industrial markets.

ProSet provides a comprehensive and innovative line of cultivation products designed for different cell culture experiments and applications. The systems are available with vessel volumes from 500ml up to 1000 litres and have a large, colour touch-screen panel which is intuitive and easy to use. Its distinctive functions include various programming operations to control the pump speed, pH level, temperature, feed, gas levels and many other customisable functions. The ProSet Fermentation System controller is able to connect to any PC for real-time recording and control of the conditions within the cultivating vessel.

The innovative design of this controller includes in built dry heating and thermostat control. This means that five different types of vessel can be connected which offers maximum flexibility.This allows the growth of almost any cell type in vessels connected to a single controller just by changing the type of vessel. Cell types include microbial aerobic and anaerobic, temperature and sheer sensitive cells such as those from mammalian or insects, plant and algae cells which can be grown using the optional photosynthesis light module, cells requiring oxygen or other gas enrichment and fungal cells in solid state fermentation.

The range is complete with fully customisable options and accessories available for gas mixing, oxygen enrichment, mass flow and gas analysis.

Welcome to ProSet Fermentation from Cleaver Scientfic

The team


All about proSET Fermentation and Cultivation Systems 3

Cleaver Scientific Company Introduction 4

Cultivation IncubatorproSET Shaking Incubator 6

Recirculating ChillerproSET Chiller 7

Bioreactor /FermentorBenchtop System Overview 8-9

proSET Vessel Selection Guide 10-11

proSET Control System 12-13

proSET Parallel System 14-15

proSET One Fermentation System 16-17

proSET Evo Fermentation System 18-19

proSET Solid State Fermentation System 20

pH Probe 21

DO Probe 21

Temperature Probe 22

ORP Probe 22

Brushless Motor 23

Motor Shaft Protection Cap 23

Fermentation Bottle Holder 24

Stainless Steel Supporting Foot / Antifoam Probe 24

Composite Vessel Handles 25

Stainless Steel Condenser 25

Loading Port 26

Sampling Device 26

Impeller / Headplate Stand 27

Photobioreactor Lighting Module 28

Oxygen Enrichment Module /

Oxygen Enrichment with Mass Flow Controller 29

CO2 / O2 Off-Gas Analyzer / Gas Mixing Station 30

External Pump 31

Optional Customized ItemsAir Sparger 32

Feeding Bottle Loading Port 32

Online Cell Density Device 32

Methane Off Gas Analyzer 32

Vessel Stand 32

Consumable Parts 33

SIP Fermentation System (Pilot & Production)Pilot and Production Scale Fermentation System 34-39

Optional Accessory Items 40-41

Ordering Information 42-46

Terms & Conditions 47

Contents


Model No. CSSI-200Platform size 18.1” x 18.1” (46 x 46 cm)

Shaking orbit 3/4” (19 mm)

Speed range (rpm) 20-500 rpm

Speed control 1 rpm

Communication port RS-485, PT-100

Heating temperature range Ambient +5oC to 65oC

Heating output 300W

Temp accuracy and uniformity ± 0.25oC at 37oC

Timer 1 min to 999 hours, continuous operation

Display 3.5" Colour TFT LCD screen

Unit dimension (WxLxH) Approx. 32.1"x 23.3" x 22.3” (Approx. 82 x 59 x 57cm)

Unit weight Approx. 154.3 lb (Approx. 70 kg)

Voltage 110 / 220V~ 50 / 60Hz

Certification CE, FCC

Cleaver Scientific is introducing our newly innovated proSET series shaking incubator. This ultimate bench-top shaking incubator provides you the stability and durability for all your fermentation and incubation needs. The system incorporate multi-safety features to put you at your ease of mind.

• Automatic shut off over temperature protection• Built-in G sensor with warning for imbalance weight detection• Safety interlock stops platform motion• External temperature probe available upon order for precision

temperature measurement• Programmable or continuous mode for user application• Wild shaking speed 20-500 rpm satisfy different types of culturing• Contamination-free coating material for complete sanitary purposes• Brushless DC motor for long and quiet operation, durable and

maintenance free usage• Various selection for accessories• Acrylic lid for clear viewing and easy access

proSET Shaking Incubator

*All images are for reference only, actual products might differ from the pictures above.*For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.

Specification

Cat. No. Product DescriptionMax. platform

capacity

SI-200-01 Universal platform 1

SI-200-02Adjustable angle Tube Rack ( 33 x 15ml )

4

SI-200-03Adjustable angle Tube Rack ( 16 x 50ml )

4

SI-200-04 Universal Spring Rack 2

SI-200-05 Sticky Pad platform 1

SI-200-06Universal Cushioned Crossbar

1

Shaking Incubator 200 series accessoryRacks and Tray Microplate and flask holder

Cat. No. Product DescriptionMax. platform

capacity

SI-200-07 Microplate holder 9

SI-200-08 Flask holder, 50 ml 52






Universal platformCat. No: SI-200-01

Adjustable angletube rack ( 16 x 50 ml )

Cat. No: SI-200-03

Sticky pad platformCat. No: SI-200-05

Adjustable angle tube rack ( 33 x 15 ml )

Cat. No: SI-200-02*tube not included

Universal spring rackCat. No: SI-200-04

Universal cushioned crossbarCat. No: SI-200-06

Microplate holders Cat. No: SI-200-07

*Different size of flask holder available as accessories.

CSSI-200

Features

6 I VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION I 7

Model No. CS-200

Platform size 18.1” x 18.1” (46 x 46 cm)

Shaking orbit 3/4” (19 mm)

Speed range (rpm) 20-500 rpm

Speed Increment 1 rpm

Communication port RS-485

Heating output Approx. 100W

Timer 1 min to 999 hours, continuous operation

Display 3.5" Color TFT LCD screen

Unit dimension (WxDxH) Approx. 32.1"x 23.3" x 22.3” (Approx. 82 x 59 x 57cm)

Unit weight Approx. 110.2 lb (Approx. 50 kg)

Voltage 110~220V~ 50 / 60Hz

Certification CE, FCC

The proSET Chiller series is Cleaver Scientific’s newest add i t i on to the b ioprocess ing technology portfol io to provide precise temperature control and excellent cooling performance for your fermentation needs and beyond. The recirculating chillers are compactly designed and require very little space; the built-on wheels offer an added bonus of mobility to any space-conscious labs. With a low procurement cost, it is your best option to stray away from costly tap water and is the perfect alternative for basic cooling needs.

• Compact design• Overheat protection• LED display with PID control of 0.1°C resolution• Self-diagnosed abnormality function• Delayed resume compressor protection• Jetstream forced-flow circulation

proSET Shaker

proSET Chiller

Specification

Specification

Features

Features

CSWCC-100 / 101

Cat. No. CSWCC-100 CSWCC-101 Operating temperature +20°C~+40°C

Display LED Display Operating humidity Max.80°C

Temperature control Range 0oC to +100oC Rated voltage 110V; 60Hz, 14.5A 220V; 50Hz, 8A

Temperature stability ± 0.5oC at 20oC Inner bath material SUS#304

Temperature accuracy ± 0.5oC at 20oC Bath inner dimension (W x L x H) 9.25"x11.61"x5.90"

(235x295x150mm)Controller PID control, PT100 sensor External material Powder Coating

Setting / display resolution ± 0.1°C Compressor 1/4HPCooling capacity (Medium Ethanol) 1900 BTU/h @ 0°C Unit dimension (W x L x H) 13.39"x22.04"x26.38"

(340x560x670mm)Pump capacity flow rate (l/min) 5.5L/min Unit weight Approx. 110.2lb (50kg)

Pump capacity flow pressure (bar) 0.19bar Safety device

"Self-diagnosed abnormality display Electronic overheating thermal fuse protection

in increments of 0.1oC Delayed resume compressor protection"

Pump connections 1/4” silicone tubing Circulation volume Cycles up to 7L/min cooling system with delayed resume protection after power outage

Barbed fittings diameter (inner dia. / mm) 6.35mm or 1/4” Circulation type Jet stream flow forced circulation, can be

accessed through the outer loopBath capacity 10L

Heater wattage 1000WRefrigerant CFC free refrigerants-R134a

Ordering Information Cat. No. Product Description CSWCC-100 proSET Chiller, 110V CSWCC-101 proSET Chiller, 220V

• Various speed settings from 20-500rpm• Equipped with a robust Brushless DC motor for

economical and noiseless operation• Two modes of operation available: Programmable

or continuous• Versatile accessories available for advanced

culturing solutions.• Auto detection and power shutdown to platform

weight imbalance or belt breakage


*All images are for reference only, actual products might differ from the pictures above.*For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.

Benchtop System Overview

The most versatile, price and space saving fermentation system is now available from our proSET Fermentation product line - The proSET One Fermentation System.proSET One is not only compact in size but also provides all the necessary tools as a standard instrument. The dual heating system allows you to choose any vessel type up to 10L for any application needs. The optional expansion module allows you to add additional devices to enhance the capability of the system. All necessities such as temperature, anti-foam, pH and DO probe are all included in the standard package.

The proSET Parallel Fermentation System offers the benefit of using two fermentation vessels with a single compact controller. Whether you need to run two identical experiments or two different experiments at once, the dual heating system allows you to run two thermostat heating, two dry heating or one thermostat and one dry heating simultaneously for complete flexibility. The state of the art design is constructed with the upmost versatility in mind and allows you to operate any vessel type and size in any combination you prefer. The remote software can control up to 16 vessels for true multi-parallel operation.

NEW

1 2

2

3 4 CSFS-06

CSFS-05

• Duo Heating system, thermostat and dry heating combined in one controller • True Parallel System, one (1) controller controls two (2) vessels• Interchangeable five (5) types of autoclavable glass vessels• Control up to eight (8) systems from a single interface • Compatible with microbial and cell culture applications• Intuitive user-interface for short learning curve • Ethernet communication with proSET SCADA software, and IP addressing• Compatible with a full range of vessel volumes from 0.5L to 20L• Full selection of optional devices available

proSET Parallel System (CSFS-05 Series)

proSET One System (CSFS-06 Series)

• Duo Heating system, thermostat and dry heating combined in one• Most versatile and compact system on the market (W250 x L510 xH500 mm)• Interchangeable five (5) types of autoclavable glass vessels• Control up to sixteen (16) systems from a single interface• Compatible with microbial and cell culture applications• Intuitive user-interface for short learning curve with multi-language support• Ethernet communication with proSET SCADA software, and IP addressing• Expansion module available for system upgrade for optional devices

4


NEW

NEW

1 2 3 5

1

2

3

4

4

5

6

6

Single wall dish bottom vessel, 1L

Double jacketed dish bottom vessel, 3L

Single wall air lifter vessel, 5L

Single wall plain bottom with heating base unit, 10L

Double jacketed air lifter vessel, 5L

Single Wall Dish Bottom Vessel with Heating Blanket, 5L

CSFS-07

CSFS-10-A05P

proSET Solid State Fermentation System

proSET Evo System (CSFS-07 Series)

*For more information, please contact your local distributors.

The proSET Solid State system is designed for ease of operation, optimization, and for scale up through built-in controller factors. It has the same specifications as the other models in the proSET series offering a 10.4" colour touch screen with graphic user interface and 4 built-in peristaltic pumps controlled by the Linux based operating system. An automatic vessel angle control mechanism via the proSET controller gives outstanding mixing efficiency and simulation for solid state material research such as enzymatic hydrolysis research with Lignocellulosic material and Ganoderma solid state. This system is designed for both aerobic and anaerobic fermentation with different optional impellers.

• 10.4” large colour touch-screen & graphical user Interface, easy to operate• Linux based system for stable operation and impervious to virus intrusion• Automatic vessel angle control mechanism from vertical to horizontal perfectly suitable for Simultaneous

Saccharification and Fermentation research• Typical applications covers enzymatic hydrolysis research with Lignocellulosic material and Ganoderma

solid state research• Temperature control environment and optional humidity control and detection• Various optional impeller choices and aeration introduction into the material available

proSET Evo is a next generation Fermentation system with dual modes of heating to allow connection of any type of vessel. proSET Evo contains greatly enhanced functionalities and capabilities including excellent versatility and system expansion capabilities.

• Duo Heating system, thermostat and dry heating combined in one• Universal System for R&D in cell culture and microbiology• Interchangeable five (5) types of autoclavable glass vessel• Control up to sixteen (16) systems from a single interface • Compatible with microbial and cell culture applications• Easy to learn operation via an intuitive user interface• Small pilot scale 15L and 20L glass vessel compatible• Ethernet communication with proSET SCADA software, and IP addressing• proSET **EZScript software for advance fermentation process


proSET Vessel Selection Guide

ControllerDuo Heating Control ( CSFS-05, CSFS-06, CSFS-07 )

Thermostat System Dry Heating System

VesselDouble Jacketed(FS-V-A series)

Single Wall(FS-V-B series)

Air Lifter(FS-V-C series)

Single Wall withHeating blanket(FS-V-B series)

Single Wall withHeating base unit(FS-V-D series)

Agitation motor Brushless motor Brushless motor N / A Brushless motor Brushless motor

Impeller Pitched-blade Rushton N / A Rushton Rushton

Temp range5 °C above coolant

to 60°C5 °C above coolant

to 60°C5 °C above coolant

to 60°C5°C above coolant

to 60°C5°C above coolant

to 90°C

Vessel size 500ml - 10L 1 - 10L5L only, single or double

jacketed1 - 20L 3 - 10L

Speed range

cell: 30 - 300rpm (0.5 - 5L)

microbial: 30 - 1000rpm (10L)

30 - 1200rpm (1 - 5L)30 - 1000rpm (10L)

N / A30 - 1200rpm (1 - 5L)30 - 1,000rpm (10L)

30 - 700rpm (15, 20L)

30 - 1200rpm (3 - 5L)30 - 1,000rpm (10L)

Heating Built-in heat exchanger Heating blanket Heating base unit

Cooling External chiller, automatic cooling water valve

Aeration Orifice ring sparger Orifice ring sparger PTFE micro sparger Orifice ring sparger Orifice ring sparger

Grounding port No need No need Yes No need No need

Application

Excellent for temperaturesensitive and shear-forcesensitive cells such as

mammalian andinsect cell cutlure

Great for aerobic oranaerobic microbial culture;suitable for plant cell and photosynthesis cell culture

Excellent for shear-sensitivecells; ideal for plant cells,fungal cells, algae cell and

photosynthesiscell culture

Ideal for rapid temperaturechange aerobic and anaerobic microbial(bacteria and yeast)

fermentation

Excellent for aerobic and

anaerobic microbial(bacteria, yeast)

culture, such as E.coli

Controller Specification

Model CSFS-05 CSFS-06CSFS-06 with

Optional expansion moduleCSFS-07

Product name proSET Parallel proSET One proSET One proSET Evo

Heating system Duo Heating

Working volume range 500ml - 20L 500ml - 10L 500ml - 10L 500ml - 20L

Glass vessels, autoclavable yes yes yes yes

Interchangeable vessels yes, all types yes, all types yes, all types yes, all types

Number of vessels controlled per Controller

2 1 1 1

Number of vessels controlled via remote software

Max 16

Touchscreen controller yes, 10.4" yes, 8" yes, 8" yes, 10.4"

Number of peristaltic pumps 8 3 3 4

Gas mixing options Available no Available, * Available

Oxygen enrichment Available no Available, * Available

Mass flow controller Available no no Available

Off gas analyzer Available no no Available

ORP probe Available no Available, * Available

Lighting module Available no Available, * Available

External pump Available, multiple Available, 1 max. Available, 2 max. Available, multiple

Mobile SMS module Available no no Available

* Optional expansion module needed. (CSFS-06-EPM)

proSET Controller Selection Guide


Vessel type Double Jacketed Dish Bottom Vessel (FS-V-A series)

Material Borosilicate glass / 316L stainless steel for headplate and all fittings

Working volume 500ml 1L 3L 5L 10L

Total volume 1L 1.5L 3.8L 6.8L 12.5L

Vessel type Single Wall Dish Bottom Vessel (FS-V-B series)


Working volume 1L 3L 5L 10L

Total volume 1.5L 3.8L 6.8L 12.5L

Vessel type Air Lifter Vessel (FS-V-C series)


Working volume 5L single wall 5L double jacketed

Total volume 7L

Vessel type Single Wall Dish Bottom Vessel with Heating Blanket (FS-V-B series)


Working volume 1L 3L 5L 10L 15L 20L

Total volume 1.5L 3.8L 6.8L 12.5L 18.7 23.7

Vessel type Single Wall Plain Bottom Vessel with Heating Base Unit (FS-V-D series)


Working volume 3L 5L 10L

Total volume 3.7L 6.7 13.1*FS-A-CON04 is pre-configured in Air Lifter Vessels as standard. Available upon purchase of vessels over 3L. ** Suggested Max.

Vessel Specification

Vessel Application

Vessel

Application

Double JacketedDish Bottom Vessel

Single WallDish Bottom Vessel

Air Lifter VesselSingle Wall Dish

Bottom Vessel with Heating blanket

Single Wall Plain Bottom Vessel with Heating Base Unit

FS-V-A series FS-V-Bseries FS-V-C series FS-V-B series FS-V-D series

Mammalian cell cultureAerobic microorganism culture (Note 1)Micro-aerobic microorganism culture (Note 2)Anaerobic microorganism culture (Note 3)Fragile cell culture (Note 4)Photosynthesis cell culture (Note 5)Plant cell cultureInsect cell culture

Not RecommendedGoodExcellent

Note:1. Some bacteria; yeast; fungi2. Facultative culture (For example, some Lactobacillus; ethanol production)3. Same as Note 24. This vessel is excellent for fragile cells that are easily sheared by any type of mechanical impeller5. Plant; algae; cyanobacteria (blue-green algae)


Control / Manual Control / Sequence Pumps

Performs manual, sequence or EZ Script control of each parameter. Control the peristaltic pump speed, direction, total volume and flow rate

Controller Layout

proSET Control System

CSFS-05

CSFS-06

CSFS-07

Ⓒ

Ⓒ

Ⓒ

Ⓕ

Ⓕ

Ⓕ

ⒹⒹ

Ⓓ

Ⓔ

Ⓖ

Ⓖ

Ⓔ

Ⓔ

Ⓐ Colour Touch Screen

Ⓑ Assignable & adjustable peristaltic pumps

Ⓒ USB port for easy data transfer

Ⓓ Power switch

Ⓔ Adjustable air flow meter

Ⓕ ABS Flame Retardant Front Panel

Ⓖ Adjustable O2 flow meter

Ⓗ Sensor Control Panel

Ⓘ Air & Cooling Control Panel

Ⓐ

Ⓐ

Ⓐ

Ⓑ

ⒷⒾ

Ⓑ


Easy operate on-screen sensor calibration

ChartingCalibration

Real-time data recording and exporting during a fermentation process with image capture capability (NEW)

System Setup

Intuitive system set up for optional devices and administration

Service

Professional parameters for fast maintenance and troubleshooting

No software purchase necessaryEthernet cable connection for remote control

*PC and switch hub are not included

Switch Hub

Intranetconnection

Directconnection

PC remote controlling software connects up to 8 systems (proSET Parallel System)

Overall Features:• Duo Heating system, thermostat and dry heating combined in one

• Interchangeable five (5) types of autoclavable glass vessel

• Compatible with a total of 20 vessels, working volume range of 500ml-20L on a single controller.

• Interchangeable five (5) types of autoclavable glass vessel

• Compatible with microbial and cell culture applications

• Highly acid and base resistant Watson Marlow pump heads

• Flexibility in data exporting, USB or PC connection

• Easy maintenance and upgrade modular system

Software Features:• Linux based system for stable and virus proof operation

• 15 steps sequential control for pH, temp., agitation and feeding program

• Intuitive user-interface for short learning curve with multi-language support

• Over 59,994 user programs and 100 process data files can be stored in controller

• pH and DO stat with smart feeding technology

• Eight (8) user accounts with secure password for maximum protection

• Real-time on-screen data viewing, recording and exporting ensures quick data analysis

• Ethernet communication with proSET SCADA software, and IP addressing

• proSET EZScript software for advance fermentation process

• Quality assurance- CE certified and ISO accredited


Vessel Single Wall with Heating Blanket (FCSS-V-B series) Single Wall with Heating Base Unit (FS-V-D series)Working volume 1L 3 L 5 L 10 L 15L 20L 3 L 5 L 10 LTotal volume 1.5L 3.8 L 6.8 L 12.5 L 18L 24.4L 3.7 L 6.4 L 13.4L

Vessel Double Jacketed (FS-V-A series) Single Wall (FS-V-B series) Air Lifter (FS-V-C series)Working volume 500ml 1L 3 L 5 L 10 L 1L 3 L 5 L 10 L 5 LTotal volume 1L 1.5L 3.8 L 6.8 L 12.5 L 1.5 L 3.8 L 6.8 L 12.5 L 7 L

*All material are made by Borosilicate glass / 316 L stainless steel for headplate and all fittings

proSET Parallel System

CSFS-05 10L Vessel 1L Vessel

Newly developed proSET

interface for easy operation

PC remote controlling software

connects up to 8 systems.

PC software connects up to 8

systems (total 16 vessels) at the

same time.

System Specification


ControllerDuo heating system controller

Built-in rotameter8x built-in pump heads, 4 pump heads on each side

Vessel

Double jacketed vessel (includes glass body,

head plate, T-handling bar, 2 probe adaptors)

Single wall dish bottom vessel (includes glass

body, head plate, T-handling bar, 2 probe

adaptors)

Airlifter vessel (includes glass body, head plate,

draft tube, T-handling bar, 2 probe adaptors)

Single wall dish bottom with heating blanket (includes glass body,

head plate, T-handling bar, 2 probe adaptors and

heating blanket)

Single wall plain bottom with heating base unit (includes glass body,


heating base unit)2 adjustable Pitched-

blade impeller3 adjustable Rushton-

type impellersno impellers

3 adjustable Rushton-type impellers


Baffle assembled Draft tube assembled Baffle assembledCondenser assembled

Air sparger assembled Micro sparger assembled Air sparger assembledMotor Agitation motor N / A Agitation motor

Probes

1x pH probe and 1x pH cable1x Do probe and 1x DO cable

1x Temperature probe and 1x Temperature cable1x anti-foam/level sensor and 1x anti-foam/level sensor cable

Start-up Kit Complete start-up kit includes, silicone tubes, tube clamps, metal connector and autoclavable disc filters, please see p.34 for details

Utility RequirementPower source 210-230V, 50-60Hz with electrical safety cutoff switch

Water source10 psig (0.69 barg), 14.5 psig (1 barg) maximum; (water supplied to fermenter must be softed and at least 15°C below set operating temperature)

Air source 10 psig (0.69 barg), 29.0 psig (2 barg) maximum; air must be dry, oil-free and filteredSterilization Autoclave; size of the autoclave inner chamber must be able to accomodate vessel with condenser attached

*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice. *Ordering information, please refer to p42-44.

Controller Specification & Vessel Comparison


Control unit

Control panel 10.4" Colour touch-screen interface

Communication port Remote software control through Ethernet, up to 8 systems per PC Data export through USB port Analog AUX port for system extension

Program storage Up to 59,994 process programs Log data storage Up to 100 process monitoring data files Cabinet material ABS front panel and painted iron housing

Dimension Footprint: W x D = 15.75" x 21.26" (400mm x 540mm); Height: 29.14" (740mm) Rated voltage 220V~; 50/60 Hz, 10A, 2000W

Aeration Inlet gas flow-meter

0,0.1-1LPM (500ml), 0, 0.2-2.5LPM (1L), 0, 1-10LPM (3, 5L), 0, 2-25LPM (10L), 0, 4-50LPM (15, 20L)

Sparger Orifice ring Baffle Removable 316L stainless steel baffles

Temperature

Heating 1. Thermostat System: built-in heat exchanger (550W heater, water circulation pump) 2. Dry heating system : external devices (heating blanket or heating base unit)

Cooling Cooling coil and solenoid valve Range 5°C (41°F) above coolant up to 60°C (140°F) Probe Platinum RTD probe (PT-100), non autoclavable

Control mode Manual or Programmable 15 steps PID control

Agitation

Drive Removable top brushless motor

Speed range 30 - 1200rpm (0.5, 1, 3, 5L) 30 - 1000rpm (10L) 30 - 700rpm (15, 20L)

Resolution 1 rpm increment

Impeller 2 impellers for 0.5-1 L vessel and double jacketed vessels 3 impellers for 3 L vessel and above Note: Customized impellers are available upon ordering


pH

Range 2 - 14pH Resolution 0.01pH

Probe Gel-filled electrode, autoclavable Control mode Manual/Acid start/progrmmable 15 steps PID control

DO

Range 0 - 200% Resolution 0.1%

Probe Polarographic DO sensor; autoclavable

Control mode

2-stage DO cascade response: (Manual or Process mode) a. Increase or decrease agitation speed b. Supply external oxygen source using solenoid valve switch (Oxygen enrichment module required, optional device) c. Adjusting DO level using accurate gas mixing control (Gas mixing station module required, optional device) Substrate feeding strategy

ORP(optional) Measurement range -/+ 2000mV

Resolution 1mV Probe Gel-filled electrode: autoclavable

Foam Probe 316L stainless steel protector with insulated PTFE tube; On/Off control, autoclavable, adjustable sensitivity control

Peristaltic Pump

Pump number 4 x built-in Watson Marlow pumps per vessel (total 8); multiple external pump extendable (MU-D series required, optional)

Motor type Precise stepping motor; minimum speed is 1rpm Speed range 0 to 65rpm Resolution 1rpm

Control mode Manual or Programmable 15 steps feeding control; pump can be assigned for Acid, Base, Antifoam and Substrate

Exhaust Device type 316L stainless steel condenser

Specification


Vessel Single Wall with Heating Blanket (FS-V-B series) Single Wall with Heating Base Unit (FS-V-D series)Working volume 1L 3 L 5 L 10 L 3 L 5 L 10 LTotal volume 1.5L 3.8 L 6.8 L 12.5 L 3.7 L 6.4 L 13.4L


proSET One Fermentation System

CSFS-06 Compatible with any vessel types up to 10 liter.

PC software connects up to

16 systems 16 vessels at

the same time.





Built-in rotameter3x built-in pump heads

Vessel





adaptors)





heating blanket)










Probes




Controller Specification & Vessel Comparison

*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice. *Ordering information, please refer to p45.

Utility RequirementPower source 100-120V / 210-230V, 50-60Hz with electrical safety cutoff switch




Control unit

Control panel 8" Colour touch-screen interface

Communication port Remote software control through Ethernet, up to 16 systems per PC Data export through USB port Analog AUX port for system extension

Program storage Up to 59,994 process programs Log data storage Up to 100 process monitoring data files Cabinet material ABS front panel and painted iron housing

Dimension Footprint: W x D = 9.84" x 20.08" (250mm x 510mm), Height: 19.69" (500mm) Rated voltage 110V~/220V; 50/60 Hz, 10A

Aeration Inlet gas flow-meter 0,0.1-1LPM (0.5L), 0, 0.2-2.5LPM (1L), 0, 1-10LPM (3, 5L), 0, 2-25LPM (10L)


Temperature

Heating 1. Thermostat System: built-in heat exchanger (550W heater, water circulation pump) 2. Dry heating system (heating blanket or heating base unit)

Cooling Cooling coil and solenoid valve

Range with FS-V-A / B / C series : 5°C (41°F) above coolant up to 60°C (140°F); with FS-V-D series :5°C(41°F) above coolant up to 90°C (194°F)

Probe Platinum RTD probe (PT-100), non autoclavable Control mode Manual or Programmable 15 steps PID control

Agitation

Drive Removable top brushless motor

Speed range a. For extremely shear-sensitive cell line: 30 - 300rpm b. For fermentation and cell culture: 30 - 1200rpm (0.5 - 5L) and 30 - 1000rpm (10L)

Resolution 1 rpm increment

Impeller 2 impellers for 0.5-1L vessel and double jacketed vessels 3 impellers for 3L vessel and above Note: Customized impellers are available upon ordering


pH


Probe Gel-filled electrode, autoclavable

Control mode Manual/Acid start/programmable 15 steps PID control with adjustable deadband, **pH stat with smart feeding technology

DO



Control mode

1-stage DO cascade response a. Increase or decrease agitation speed **b. Supply external oxygen source using solenoid valve switch (Oxygen enrichment module required, optional device) **c. Adjusting DO level using accurate gas mixing control (Gas mixing station module required, optional device) **DO stat with smart feeding technology



Foam / Level Probe 316L stainless steel protector with insulated PTFE tube, autoclavable, adjustable sensitivity control

Control Mode Foam: On/Off switch Level: On/Off switch control with wet/dry probe set up

Peristaltic Pump

Pump number 3 x built-in Watson Marlow pumps, **1-2 external pump extendable (MU-D series required, optional)

Motor type Precise stepping motor; minimum speed is 1rpm Speed range 0 to 65rpm Resolution 1rpm

Control mode Manual or Programmable 15 steps feeding control; pump can be assigned for Acid, Base, Antifoam and Substrate; **flow rate & total volume calculation


Specification

** Expansion module (CSFS-06-EPM) required.


Vessel Single Wall with Heating Blanket (FS-V-B series) Single Wall with Heating Base Unit (FS-V-D series)Working volume 1L 3 L 5 L 10 L 15L 20L 3 L 5 L 10 LTotal volume 1.5L 3.8 L 6.8 L 12.5 L 18L 24.4L 3.7 L 6.4 L 13.4L






Built-in rotameter4 x built-in pump heads

Vessel





adaptors)





heating blanket)










Probes




proSET Evo Fermentation SystemController Specification & Vessel Comparison

CSFS-07

Utility RequirementPower source 100-120V / 210-230V, 50-60Hz with electrical safety cutoff switch



*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice. *Ordering information, please refer to p46.

PC software connects up to

16 systems 16 vessels at

the same time.


Control unit

Control panel 10.4” colour touch-screen Interface (Resolution: 800 x 600 pixels)

Communication port Remote control through Ethernet Data export through USB port Analog AUX port for system extension

Number of vessels controlled per remote control software

Max. 16

Program storage Up to 59,994 programs for different kinds of condition Log data storage Up to 100 process monitoring data files Cabinet material ABS front panel and painted iron housing

Dimension Footprint: W x D = 15.75" x 22.44" (400mm x 570mm); Height: 29.14" (740mm) Rated voltage 110V~/220V~; 50/60 Hz, 10A

Aeration Inlet gas flow-meter

0, 0.1-1LPM (0.5L); 0, 0.4 - 5LPM (1L); 0, 1 - 10LPM (3, 5L); 0, 2 - 20LPM (10L); 0, 4 – 50LPM (15, 20L)


Temperature

Heating 1. Thermostat System: built-in heat exchanger (550W heater, water circulation pump) 2. Dry heating system (heating blanket or heating base unit)

Cooling Cooling coil valve

Range with FS-V-A / B / C series : 5°C (41°F) above coolant up to 60°C (140°F); with FS-V-D series :5°C(41°F) above coolant up to 90°C (194°F)

Probe Platinum RTD probe (PT-100), non autoclavable Control mode Manual or Programmable 15 steps PID control

Agitation

Drive Removable top brushless motor (M3 for 0.5L, 1L; M2 for 3~20L)

Speed range a. For extremely shear-sensitive cell line: 30-300rpm b. For fermentation and cell culture: 30 - 1200rpm (0.5-5L); 30 - 1000rpm (10L); 30 – 700rpm(15, 20L)

Resolution 1rpm

Impeller 2 impellers for 0.5L &1L vessel and double jacketed vessels 3 impellers for 3L vessel and above Note: Customized impellers are available upon ordering


pH


Probe Gel-filled electrode, autoclavable

Control mode Manual/programmable 15 steps PID control with adjustable deadband, pH stat with smart feeding technology

DO



Control mode

2-stage DO cascade response a. Increase or decrease agitation speed b. Oxygen Enrichment module(Optional) c. Gas Mixing Station module(Optional) DO stat with smart feeding technology



Foam / Level Probe

316L stainless steel protector with insulated PTFE tube, autoclavable, adjustable sensitivity control

Control Mode Foam: On/Off switch Level: On/Off switch control with wet/dry probe set up

Peristaltic Pump

Pump number 4 x built-in pumps, 1 to 2 external pumps (Optional) Motor type Precise stepping motor; minimum speed is 1rpm

Speed range 0 to 65rpm Resolution 1rpm

Control mode Manual or Programmable 15 steps feeding control; pump can be assigned for Acid, Base, Antifoam and/or Substrate; pump can calculate flow rate and total volume


Specification

20 I VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION20 I VISIT WWW.CLEAVERSCIENTIFIC.COM OR CALL +44 (0) 1788 565300 FOR MORE INFORMATION

Specification

Control Unit

Control Panel 10.4” colour touch-screen Interface, (Resolution: 800 x 600 pixels)Communication Port Remote control through Ethernet, Analog AUX port for system extensionStorage Program Up to 59,994 programs for different kinds of condition.Data Internal Storage Up to 100 data files.Data External Storage Interface USB portCabinet Material Front panel: ABS / Housing: Painted ironDimension Footprint: W x D = 15.75" x 22.44" (400 x 570mm); Heigh: 29.14" (740mm)Rated Voltage 110V~/ 220V~ ; 50/60 Hz

Aeration Inlet Gas Flow-meter 0, 1 - 10LPM (5L only)

Temperature

Heating Thermostat system: Built-in heat exchanger, 550W heater/water circulation pumpCooling Automatic cooling water valveRange 5°C (41°F ) above coolant up to 60°C (140°F )Resolution 0.1°CControl Mode Manual or programmable 15 steps PID control.

Agitation

Drive Removable top brushless motor Speed Range 30 - 1200rpmResolution 1rpmControl Mode Manual or programmable 15 steps PID control.Impeller Double Helix shape impeller

CSFS-10-A05P

proSET Solid State Fermentation System

Special Features:

• 10.4” large colour touch-screen & graphical user Interface, easy to operate• Linux based system for stable operation and impervious to virus intrusion• Automatic vessel angle control mechanism from vertical to horizontal perfectly suitable

for Simultaneous Saccharification and Fermentation research• Typical applications covers enzymatic hydrolysis research with Lignocellulosic

material and Ganoderma solid status research• Temperature control environment and optional humidity control and detection• Various optional impeller choices and aeration introduction into the material available

*Ordering information, please refer to p.42-46

Up to 90° rotation

Side view Front view*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.


ACCESSORY ITEMS


DO sensor type Polarographic

Dissolved oxygen 0.1- 200% air saturation 10 ppb to saturation

Temperature 0 - 135°C (275°F) Resolution 0.1% Pressure 4 bar maximum Temperature compensation 22 kohm thermistor Wetted materials 316L S.S. Shaft diameter 12mm Surface finish Ra 12 (electro-polished)

pH ProbeThis state-of-the-art, gel-filled low maintenance pH-electrode with excellent pressure resistance is specifically developed for reliable measurements in bioprocesses. With pressure resistance of up to 6 bar overpressure and silver-ion trap to prevent fouling of the diaphragm in sulfide-bearing media, the glass body pH electrode can be used on an universal basis in bioprocess applications.

Features• Fast response• Proven reliability• High resolution and precision• Suitable for autoclave, SIP and CIP• User-calibration available

DO ProbeThis stainless steel constructed dissolved oxygen sensor is designed for maximum accuracy and reliability. A Modular and robust design along with state-of-the-art interior sensor design allows for easy disassembly for maintenance. A PTFE/silicone membrane designed with an internal steel mesh makes the membrane more rugged, drastically improving repeatability of these senors in bioprocess applications.

Features• Fast response• Proven reliability• High resolution and precision• Suitable for autoclave, SIP and CIP• User-calibration available

Specification

Ordering Information

pH range 2 -14 (2-12 for maximum precision) Temperature 0-135°C (275°F) Resolution of pH 0.01 Pressure 6 bar maximum Shaft diameter 12 mm Connection Pg 13.5 Temperature compensation Integral Pt 100 (VP model)

Cat. No. Product Description FS-A-PPH00-MT pH Electrode Cable, AK9 Type, Mettler Toledo FS-A-PPH01-MT 120mm pH Probe for 0.5L,1L vessel,Mettler Toledo FS-A-PPH02-MT 225mm pH Probe for 3L vessel, Mettler Toledo FS-A-PPH03-MT 325mm pH Probe for 5-15L vessel, Mettler Toledo FS-A-PPH04-MT 425mm pH Probe for 20L vessel, Mettler Toledo

FS-A-PPH00-HM pH Electrode Cable, AK9 Type, Hamilton FS-A-PPH01-HM 120mm pH Probe for 0.5L, 1L vessel, Hamilton FS-A-PPH02-HM 225mm pH Probe for 3L vessel, Hamilton FS-A-PPH03-HM 325mm pH Probe for 5-15L vessel, Hamilton FS-A-PPH04-HM 425mm pH Probe for 20L vessel, Hamilton

Specification

Ordering Information Cat. No. Product Description FS-A-PDO00-MT DO Probe Cable VP Type, Mettler Toledo FS-A-PDO01-MT 120mm DO Probe for 0.5L,1L vessel,Mettler Toledo FS-A-PDO02-MT 220mm DO Probe for 3L vessel, Mettler Toledo FS-A-PDO03-MT 320mm DO Probe for 5-15L vessel, Mettler Toledo FS-A-PDO04-MT 420mm DO Probe for 20L vessel, Mettler Toledo

FS-A-PDO00-HM DO Probe Cable VP Type, Hamilton FS-A-PDO01-HM 120mm DO Probe for 0.5L, 1L vessel, Hamilton FS-A-PDO02-HM 225mm DO Probe for 3L vessel, Hamilton FS-A-PDO03-HM 325mm DO Probe for 5-15L vessel, Hamilton FS-A-PDO04-HM 425mm DO Probe for 20L vessel, Hamilton

FS-A-PPH01-HM FS-A-PDO01-HMFS-A-PPH01-MT CSFS-A-PDO01-MT


ACCESSORY ITEMS

Temperature Probe

This temperature probe is placed inside a stainless steel tube in the head plate to measure the vessel temperature while maintaining sterility. With high accuracy and proven reliability, it is appliable to all of our fermentation systems in all kinds of fermentation conditions.

Features• High accuracy PT100 sensors- Platinum resistance thermometers (PRTs)• Customized length- we offer the most suitable probe lengths for different vessel sizes• Proven reliability• Non-autoclavable

Specification


Housing material 316L stainless steel Accuracy +/- 0.2°C Resolution 0.1°C

Cat. No. Product Description FS-A-PPT00 Temperature Probe Cable FS-A-PPT01 150mm Temperature probe for 0.5L vessel FS-A-PPT02 250mm Temperature Probe for 1L, 3L vessel FS-A-PPT03 350mm Temperature Probe for 5 vessel FS-A-PPT04 400mm Temperature Probe for 10-15L vessel FS-A-PPT05 550mm Temperature Probe for 20L vessel

Features• Designed to use for proSET fermentation system• Low maintenance• Fully autoclaveable sensor• Long operation lifetime

ORP (Oxidation-Reduction Potential) Probe

This ORP probe is an optional accessory for the proSET fermentation system. It measures the oxidation-reduction potential of the fermented media, which could be an indicator for anaerobic conditions/reactions. This low-maintenance and sterilizable probe is designed to withstand repeated autoclave cycles without any decline in measuring accuracy.

Specification


Electrode Gel-filled, Low-maintenance Redox electrode

Scale mV

Temperature range 0 - 130°C (32 - 266 °F) Autoclavable Yes

Cat. No. Product Description

FS-A-PORP00 ORP probe cable

FS-A-PORP01120mm ORP probe, measurement range from -2000~2000mV, for 0.5L, 1L vessel

FS-A-PORP02225mm ORP probe, measurement range from -2000~2000mV, for 3L vessel

FS-A-PORP03325mm ORP probe, measurement range from -2000~2000mV, for 5L-15L vessel and above

FS-A-PORP04425mm ORP probe, measurement range from -2000~2000mV, for 20L vessel

ORP monitoring Kit

FS-O-ORP-101ORP monitoring kit, includes 120mm ORP Probe, ORP Probe Cable, and Probe Adaptor




*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.


ACCESSORY ITEMS

Features• Low noise• Low vibration• Controlled torque• Smooth operation• Long life• Minimal maintenance

Brushless Motor

Our special designed brushless motor fits on all of our systems to avoid emission of carbon particles. The lower voltage design also provides a higher safety level to the operator.

FS-M2 FS-M3

Specification


Motor type 24V DC Brushless motor

Connection with vessel Quick connector, no tools required


FS-M2

Agitation Motor, 30 -1200 rpm for 3-5L Vessel; 30 -1000 rpm for 10L Vessel; 30 - 700 rpm for 15, 20L Vessel

FS-M3Agitation motor, 30-1200rpm for 0.5L, 1L Vessel

FS-A-MCAP

Motor Shaft Protection CapMotor Shaft Protection Cap is designed for the motor shaft of FS Series Glass Vessels. The cap can be used when the fermentor is not in use or during sterilization. Cleaver Scientific provides a convenient and simple way to protect the motor shaft from any possible damage caused by environment.

Specification

Cat. No. FS-A-MCAPCap Dimension 125 x 47.5 mm (W x H)Pull-Ring Dimension

25.4 x 10 mm (W x H)

Material Stainless Steel SUS304

Features• Stainless steel construction• Suitable for all vessel types• Protect the motor shaft from when the fermentor is not in use or during sterilization


Cat. No. Product DescriptionMESS-SS-MCAP-000 Stainless Steel Protected Cap


ACCESSORY ITEMS


Fermentation Bottle HolderThis simple stainless steel constructed feeding bottle holder fits perfectly within our glass vessel. No tools are required for assembly for easy instillation. Each bottle holder can hold up to 2x 250ml bottles.

SpecificationCat. No. FS-O-BH01Dimension 190 x 90 x 70 mm ( W x L x H )Compatible Bottle Size 2 bottles / ⌀ 70 / 250mlWeight 0.38 kgMaterial Stainless Steel SUS316LL

Features• Easy installation• Light weight• Capable of loading two ⌀ 70 bottles


Cat. No. Product DescriptionFS-O-BH01 Fermentation bottle holder

Stainless Steel Supporting FootThe stainless steel supporting foot is designed to provide a more steady position for your vessel. This stainless steel foot is suitable for all vessel types and is easy to install.

Features• Stainless steel construction• Suitable for all vessel types• No additional tools required for installation• Autoclavable

PFSV-D54-000-R01

SpecificationCat. No. PFSV-D54-000-R01Dimension ⌀ 50 X 25 mmMaterial Stainless Steel SUS316L



PFSV-D54-000-R01Stainless steel supporting foot for 0.5~10L vessels

Antifoam Probe

This antifoam probe is height-adjustable with proven reliability. It can be equipped with our controllers for the vessels. Once foaming is detected within the vessel, the controller unit will respond by pumping defoamer solution to disperse the foam and ensure the experiment progresses properly. This will ensure your experiment runs smoothly without worrying about foam formation.

Specification


Housing material Stainless steel tips and PTFE body Sensitivity Adjustable via controlling software

Cat. No. Product Description FS-A-PLV00 Foam/Level Sensor Cable FS-A-PLV02 Foam/Level Sensor with PTFE black coating

Features• Adjustable height• Made with stainless steel tips and PTFE coating• Proven reliability• Suitable for autoclave, SIP, CIP

Adjustable height for foam sensitivity


ACCESSORY ITEMS

Composite Vessel HandlesOur stainless steel composite handle is now available as an accessory for you to choose. These handles are specially designed for ease of use when lifting or moving the vessel in facilities with a horizontal autoclave or hard to reach area.

Features• Stainless steel• Ease of use, no extra tool needed• Compatible with all types of proSET vessels

Specification



FS-A-CH-01Composite handle for Fermentation vessel size 0.5L, 1L, 3L, 5L and 10L (2 per set)

FS-A-CH-02Composite handle for Fermentation vessel size 15L and 20L (2 per set)

Construction materialSUS316L (Vertical T-bar handling)SUS304 (Horizontal handling ear)

Unit dimensionW50 x L80 x H114 mm (FS-A-CH-01)W65 x L80 x H115 mm (FS-A-CH-02)

Loading weight 30 kg / per handle

FS-A-CH-01FS-A-CH-02

Composite vessel handles for easy vessel lifting

Features• Stainless steel construction• Quick connector assembled for easy operation• Compatible with all types of proSET vessels

Stainless Steel CondenserproSET offers flexibility in our condenser to help you maintain the best performance for your experiment. All of our fermentation condensers are constructed from SUS316L stainless steel with quick connector installment. The quick connector brings you quick and convenience during system installation. The newly designed 360° condenser (FS-A-CON04) for the Air Lifter vessel allows you to dramatically reduce the height to fit in a conventional autoclave. A Condenser is included in the vessel package.

Specification


Cat. No. Product DescriptionFS-A-CON01 Stainless Steel Condenser, 3L vessel only

FS-A-CON02 Stainless Steel Condenser, 5 - 10L vessels

FS-A-CON03 Stainless Steel Condenser, 15 - 20L vessels

FS-A-CON04 Stainless Steel Condenser, Air lifter vessel

FS-A-CON05 Stainless Steel Condenser, 0.5 - 1L vessels only

Stainless steel condenser FS-A-CON01 FS-A-CON02

Suitable vessel size 3L vessel only 5 - 10L vessels

Construction material SUS316LHeight 257.6 mm 210.6 mmO.D. for outlet 6.35 mm

Stainless steel condenser FS-A-CON03 FS-A-CON04Suitable vessel size 15 - 20L vessels Air lifter vesselConstruction material SUS316L

Height 214.1 mm281.76 mm (1)

96 mm (2)O.D. for outlet 12.7 mm 6.35 mm

Stainless steel condenser CSFS-A-CON05Suitable vessel size 0.5 - 1L vesselsConstruction material SUS316LHeight 200mmO.D. for outlet 6.35mm

FS-A-CON01 FS-A-CON02 FS-A-CON03

*Condenser customization is available upon request.*

Stainless Steel Supporting Foot


ACCESSORY ITEMS

Features• Easy and simple sampling device• Ensure sterility during sampling

Sampling Device

Our simple and intuitive sampling devices allow you to aseptically take out your sample for cell density measurements.

The tr i-port design ensures your sample is ster i le and contamination-free when sampling. For stainless steel ball valve and sanitary valve sampling device, please contact your regional managers for detailed information.

Specification

Ordering InformationCat. No. Product DescriptionFS-ACC-001 Triport sampling device, 15mlFS-ACC-002 Dual ports sampling device, 15ml

Stainless Steel ball valve sampling deviceFS-ACC-011 For FS-V-B01, FS-V-A01, FS-V-AS5FS-ACC-012 For FS-V-A03, FS-V-B03, FS-V-D03FS-ACC-013 For FS-V-D05, FS-V-A05, FS-V-B05FS-ACC-015 For FS-V-B10, FS-V-A10FS-ACC-016 For FS-V-D10 FS-ACC-017 For FS-V-B15, FS-V-C053, FS-V-C054FS-ACC-018 For FS-V-C051, FS-V-C052FS-ACC-019 For FS-V-B20

Stainless Steel sanitary valve sampling deviceFS-ACC-021 For FS-V-B01, FS-V-A01, FS-V-AS5FS-ACC-022 For FS-V-A03, FS-V-B03, FS-V-D03FS-ACC-023 For FS-V-D05, FS-V-A05, FS-V-B05FS-ACC-025 For FS-V-B10, FS-V-A10FS-ACC-026 For FS-V-D10FS-ACC-027 For FS-V-B15, FS-V-C053, FS-V-C054FS-ACC-028 For FS-V-C051, FS-V-C052FS-ACC-029 For FS-V-B20

Tube capacity 15 mlConstruction material SUS316L


Features• Stainless steel construction• Easy assemble• Customization available

Specification

Ordering InformationCat. No. Product Description

PFSV-A05-003-R01 Twin Loading Port for 3L-20L vessels

PFSV-D55-000-R01Microbial large inoculation port, suitable for vessel 3L only

PFSV-A54-000-R01Microbial large inoculation port, suitable for vessel 5L and above.

PFSV-C86-003-R01 Quad Loading Port for 1L vesselFS-A-LP02 Quad Loading Port for 3L~20L vessels

Loading Port

We offer customized feeding/loading port according to your need. Whether a larger/smaller diameter or extra ports, we are fully capable of customization based on the specific request. Evaluation upon request.

Cat. No. PFSV-A05-003-R01Suitable vessel size 3 - 20L vesselsConstruction material SUS316LUnit dimension ⌀ 30.3 x 80.1 L (mm)

Cat. No. PFSV-C86-003-R01 FS-A-LP02Suitable vessel size 1L vessel only 3 - 20L vesselsConstruction material SUS316LUnit dimension ⌀ 30.3 x 35 L (mm) ⌀ 24 x 45 L (mm)

Cat. No. PFSV-D55-000-R01 PFSV-A54-000-R01

Suitable vessel sizevessel 3L or less (excluding 1L)

vessel 5L and above

Construction material SUS316L


ACCESSORY ITEMS

Features• Stable configuration• Easy to use• Stainless steel construction• Light weight

Specification

Ordering InformationCat. No. Product Description

FS-A-HS01 Headplate Stand for 1L vesselFS-A-HS02 Headplate Stand for 3-5L vesselFS-A-HS03 Headplate Stand for 10L vesselFS-A-HS04 Headplate Stand for 15-20L vesselFS-A-HS05 Headplate Stand for Air Lifter (FS-V-C series) vessel

Cat. No. Dimension Material

FS-A-HS01

Total: 170 x 170 x 213mmHeadplate Holder: ⌀ 170 x 2TBottom Plate: 170 x 170 x 3TPole: ⌀ 10 x 200L

Stainless ( SUS304 )

FS-A-HS02


FS-A-HS03


FS-A-HS04


FS-A-HS05


FS-A-HS03

Headplate Stand

Our customized headplate stand provides a suitable and stable home for your headplate whenever the headplate is removed from the glass vessel. This reduces the possibility of damage caused by misplacement of the headplate.

Features• 316 stainless steel construction• Height adjustable• Angle adjustable (pitched blade only)• Customization available



FS-A-IM101 Rushton 6-Blade Impeller, suitable for 0.5L, 1 Liter Vessel, 2/pk

FS-A-IM103 Rushton 6-Blade Impeller, suitable for 3 Liter Vessel, 3/pkFS-A-IM105 Rushton 6-Blade Impeller, suitable for 5 Liter Vessel, 3/pkFS-A-IM110 Rushton 6-Blade Impeller, suitable for 10 Liter Vessel, 3/pkFS-A-IM120 Rushton 6-Blade Impeller, for 15 Liter or 20 Liter Vessel, 3/pk

FS-A-IM201 Pitched Blade Impeller, suitable for 0.5L, 1 Liter Vessel, 2/pkFS-A-IM203 Pitched Blade Impeller, suitable for 3 Liter Vessel, 2/pkFS-A-IM205 Pitched Blade Impeller, suitable for 5 Liter Vessel, 2/pkFS-A-IM210 Pitched Blade Impeller, stuitable for 10 Liter Vessel, 3/pk

FS-A-IM220 Pitched Blade Impeller, suitable for 15 Liter or 20 Liter Vessel, 3/pk

FS-O-DB-01 Foam Breaker Impeller, 95mm, suitable for FS-V-A10 and FS-V-B10

FS-O-DB-02 Foam Breaker Impeller, 110mm, suitable for FS-V-B15 and FS-V-B20

FS-O-DB-03 Foam Breaker Impeller, 130mm, suitable for FS-V-D10 only

Specification

Construction material SUS316L

Foam Breaker Impeller installed

Impeller

Two standard agitation impellers are available for your selection. Whereas Rushton 6-blade impeller offers high shearing force; the pitched blade offers moderate shearing force for your sensitive and fragile experiment. The Foam-breaking impeller helps to maintain a foam free environment


ACCESSORY ITEMS

Features• Utilizes artificial light to simulate bio-photosynthesis reaction• Adjust light intensity manually or automatically• Fluorescent light source• On-Off timer feature• Expandable up to 3 lighting modules• 15 steps programmable lighting schedule• Ideal for plant algae, or cyanobacteria experiments

Photobioreactor Lighting ModuleproSET offers the exclusive lighting module for our proSET systems. The specially designed lighting module is suitable for running any photon-related lab experiments such as photosynthesis reaction. This lighting module is constructed with sleek stainless steel for better appearance and reflection when light shines through the vessel. proSET software consists of 15 steps program, LUX adjustment, and self-calibration mode.

Specification


Light intensity control range 5-100%Light module 3 Fluorescent lamps / each moduleLamp specification T5/14W, Ø16mmxL549mmLight colour temperature 6500 KLuminous flux per lamp 1150 lmSensor type Light Intensity sensor, Photo diodeLux Max. 10000 luxControl mode On/off and Timed controlExpandable modules Up to 3 sets of the lighting modulesUnit dimension W200 x L326 x H648 mmWeight Approx. 7 Kg / each moduleRated voltage 110/220V~(Selectable), 50/60Hz, 5A

Cat. No. Product DescriptionFS-O-PB-1 Photo-Bioreactor Lighting Module, 1 unitFS-O-PB-2 Photo-Bioreactor Lighting Module, 2 unitsFS-O-PB-3 Photo-Bioreactor Lighting Module, 3 units

15 steps programmable lighting schedule

*FS-V-C054 + FS-O-PB-2

*For best result, a minimum of 2 units of photo-Bioreactor lighting module is required.*All images are for reference only, actual products might differ from the pictures above. *For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.


ACCESSORY ITEMS

Features• Maintain aerobic environment for fermentation process• Designed for high cell density and cells with high oxygen requirements• Precise control of DO level• Controlled manually or via DO control loop• Manually flow rate adjustment via flow meter; flow rate duration via solenoid valve

Oxygen Enrichment ModuleThis oxygen enrichment module is an optional device for fermentation processes. It enables the proSET system to support your culture with the addition of oxygen gas. The enrichment module consists of a gas pressure gauge, solenoid valve, and a flow meter. These components allow the external connection of oxygen to flow into the proSET controller to be regulated either manually or automatically.

Features• Resistant to flow variability from gas pressure changes• Automatic control of flow rate to gas input• Precise control of gas flow rate• Controlled manually or via DO Cascade feature• Hassle-free: comes built-in to the controller

Oxygen Enrichment with Mass Flow controllerThe mass flow controller is an oxygen supplementation device for your proSET system. It is capable of accurately adjusting the flow rate of the external oxygen to control the DO level within the vessel under DO Cascade mode. It features great resistance to fluctuations in gas flow which ensures precise control and repeatability for your experimental conditions.

Specification


ComponentsIncludes a manual rotameter and a pulsed control valve

Function(1) Manual oxygen flow rate adjustment (via rotameter)(2) DO cascade control: Response to DO change

Rotameterrange

1L, 3L, 5L 0, 0.4 – 5 LPM10L 0, 1 – 10 LPM

15L, 20L 0, 2 – 20 LPM


FS-O-OEO2 Enrichment Module, includes Oxygen Enrichment Valve and Adjustable Flow Meter

FS-O-OE01O2 Enrichment Module, includings Oxygen enrichment valve and adjustable flow meter for Parallel Fermentation System, single module

FS-O-OE02O2 Enrichment Module, includings Oxygen enrichment valve and adjustable flow meter for Parallel Fermentation System, dual module

FS-O-OE03O2 Enrichment Module, includings Oxygen enrichment valve and adjustable flow meter for proSET One Fermentation System

Specification


ComponentsIncludes a manual rotameter and a mass flow controller

Function(1) Manual oxygen flow rate adjustment (via Mass flow controller)(2) DO cascade control: Response to DO change

Rotameter range1L, 3L, 5L 0 – 5 LPM

10L 0 – 10 LPM15L, 20L 0 - 20 LPM

Cat. No. Product DescriptionFS-O-MF Oxygen Enrichment with Mass Flow controller

FS-O-MF01Mass flow controller for Parallel Fermentation System, single module

FS-O-MF02Mass flow controller for Parallel Fermentation System, dual module

Manually opens the solenoid valve to permit inflow of O2 O2 flowrate adjustment

*when purchasing oxygen enrichment module with CO2/O2 off gas analyzer, CO2 could be regulated and controlled**note: for CO2 gases control purposes, it requires the installation of Gas Analyzer (CSFS-O-GA)


ACCESSORY ITEMS

Features• Instant monitoring of bioreactor metabolic activity• Directly connected to controller for real-time monitoring, recording, and data export to PC• Sturdy, compact housing fits directly on top of proSET control unit• Long-life, durable, O2 and CO2 sensors• Integrated soda lime column for self-calibration of CO2 detector• External copper sulfate column absorbs moisture from inlet gas, ensuring accurate gas measurements

CO2 /O2 Off-Gas AnalyzerThe proSET CO2 /O2 off-gas analyzer provides real-t ime measurements of carbon dioxide and oxygen concentration of the bioreactor exhaust gas. The CO2 concentration is determined using a self-calibrating non-dispersion infrared sensor, while an electrochemical sensor monitors the oxygen concentration. Using this information, the user can continuously monitor metabolism and analyze cell growth parameters.

Features• Perfect for cell cultivation• Blend air, oxygen, carbon dioxide and nitrogen in any proportion to optimize cell growth• Adjust pH using carbon dioxide; avoid media dilution by addition of liquid acid• Control DO by addition of oxygen gas and nitrogen gas• User specificied gas flow rate for individual gas• Operated under manual or automatic mode• Integrated with DO cascade for precise DO control

Gas Mixing StationThe proSET Gas Mixing Station allows you to optimize cell growth condtions by independently supplying up to four gasses to the fermentation process. Parameters such as dissolved oxygen and pH can be controlled by adjusting the gas composition supplied to the system. Four manually adjusted flow meters control the flow rate of each gas, while the 4 solenoid valves automatically open or close in response to the culture conditions.

Specification


Carbon Dioxide Oxygen

Range0-10% (selectable ranges available)

0 – 50%

Detector typeNon-dispersion Infrared(NDIR)

Electrochemical

Accuracy ±5% ±1% (full scale)Response time 1.6 seconds 14±2 secondsOperating humidity 5 - 95% RH

CalibrationAuto-zero; Default

value present in factory (Built-in initialization)

Air or Calibration gas

Sample delivery Inboard sample pumpSample connection 1/4” (6.35mm) fittings for gas inlet/outlet portsSample flow rate 300 - 1000 ml/minFlow meter range 100 - 1000 ml/minPower requirement 110 – 230 V AC, 50/60HzFuse rating 2 AmpDimension 190 x 355 x 230 mm ( H x W x D )

*CO2 measurement range needs to be clarified when ordering.

Cat. No. Product DescriptionFS-O-GA CO2 /O2 off-gas analyzer

Specification


Control gases Air, N2, O2 and CO2

Control parameter DO and pH

Components4 solenoid valves, 4 pressure gauges and

4 rotameters

DO cascadeOne-way (O2) or Bi-directional (O2 & N2)

DO controlVessel size 1L 3L 5L 10L

Microbial(lpm)(standard spec)

Air 2 6 10 20O2 1 3 5 10N2 0.5 1.5 2.5 5CO2 0.5 1.5 2.5 5

Cell culture(lpm)(standard spec)

Air 0.2 0.6 1 2O2 0.1 0.3 0.5 1N2 0.1 0.3 0.5 1CO2 0.1 0.3 0.5 1

Control mode Manual or AutomaticIndicator LED indicatorAir connection 1/4” (6.35mm) fitting for gas inlet/outlet

* Customizing gas flow rate is available upon request.

Cat. No. Product DescriptionFS-O-GM Gas Mixing Station*All images are for reference only, actual products might differ from the pictures above.

*For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.


ACCESSORY ITEMS

Gas Mixing StationFeatures• Microprocessor controller• Compact size• Easy load pump head• Wide applications• Reversible for purging• Capable of 2 pump heads installation (MU-D01 / MU-D02 only)

External PumpOur MU-D series of digital control peristaltic pumps fits perfectly with our proSET series. This easy-to-use pump design allows different silicone tubing sizes to be fitted. With the capability of reverse your flow direction, it provides conveneince and flexibility to the operators.

Specification


Peristaltic pump MU-D01 MU-D02 MU-D03 Controller Digital Microprocessor Controller Motor type Brushless motor Power 50W 100W Pump speed / Inc. 20~300rpm / 1rpm 5~600 rpm / 1rpm 20~300rpm / 1rpm Variable flow rate 1.2~1,140ml / min 0.3~2,280ml / min 0.8~3,300ml / min Number of rollers 3 2 Operating temperature Ambient to 40°C

Unit dimension ( W x L x H )7.87” x 13.39” x 5.12”(200 x 340 x 130 mm)

13.39” x 9.45” x 6.69”(340 x 240 x 170 mm)

Construction Painted iron metal Weight Approx. 12.54 lb (5.7 kg) Approx. 13.42 lb (6.1 kg) Rated voltages 110V / 220V 100 ~240V 100 ~ 240V

Cat. No. Product Description MU-D01 Digital Peristaltic Pump, 110V / 220V MU-D02 Superior Digital Peristaltic Pump, 100 ~ 240V MU-D03 Supreme Digital Peristaltic Pump, 100 ~ 240V PWI-CSFS-05-00000000 Digital Peristlatic Pump Connection Cable for CSFS-05 PWI-FS-06-00000000 Digital Peristlatic Pump Connection Cable for CSFS-06, CSFS-07

Accessories Cat. No. Product Description MU-S13 Silicone tube I.D. 1/32" (0.8mm), 25ft (7.6m) MU-S14 Silicone tube I.D. 1/16" (1.6mm), 25ft (7.6m) MU-S16 Silicone tube I.D. 1/8" (3.1mm), 25ft (7.6m) MU-S25 Silicone tube I.D. 3/16" (4.8mm), 25ft (7.6m)

Cat. No.: MU-D01 /MU-D02

Cat. No.: MU-D03


ACCESSORY ITEMS OPTIONAL CUSTOMISED ITEMS

n Air SpargerFor different applications such as acid and base resistance, our customzied PTFE coated air sparger allows you to ferment under extreme conditions. Other customized spargers are also available upon request.

n Feeding Bottle Loading PortWe offer customized feeding bottle loading ports according to your needs. Whether a larger/smaller diameter or extra ports are required, we are fully capable of customization based on the specification requested. Evaluation upon request.

n Online Cell Density DeviceOur special implemented online cell density device allows you to obtain direct information about your cell growth rate and cell density. These values are critical to many bacterial, yeast and animal cell cultures by combining the monitoring and probing system into one, with high accuracy and access, monitoring cell growth is as easy as 1-2-3. Having trouble determining the cell growth rate? Our online cell density is the key to your solution.

n Methane Off Gas AnalyzerCM-FS-CH4MFM-001

The proSET CH4 off-gas analyzer provides real-time measurements of methane gas of the bioreactor exhaust gas. The CH4 off-gas analyzer connects directly to the proSET controller for easy operation and data collection.

n Vessel StandOur customized vessel stand provides a suitable and stable home due to various restrictions from the autoclave. The vessel can be set at an angle to fit the autoclave height restrictions.

Vessel Stand Vessel not included

Features

• Combination of monitor and probe system for detecting cell density• Ideal for any cell culture and fermentation experiments• High accuracy, easy access• Operate with wide application



ACCESSORY ITEMS


CONSUMABLE PARTS

Cat. No. Product DescriptionFS-A-CK-AS5 FS-V-AS5 Consumables Kit, including O-rings, Silicone tubes, Silicone stopper, Connector and Cap FS-A-CK-A01 FS-V-A01 Consumables Kit, including O-rings, Silicone tubes, Silicone stopper, Connector and Cap FS-A-CK-A03 FS-V-A03 Consumables Kit, including O-rings, Silicone tubes, Silicone stopper, Connector and CapFS-A-CK-A05 FS-V-A05 Consumables Kit, including O-rings, Silicone tubes, Silicone stopper, Connector and CapFS-A-CK-A10 FS-V-A10 Consumables Kit, including O-rings, Silicone tubes, Silicone stopper, Connector and Cap FS-A-CK-B01 FS-V-B01 Consumables kit, including O-rings, Silicone tubes and Silicone stopperFS-A-CK-B03 FS-V-B03 Consumable kit, including O-rings, Silicone tubes and Silicone stopperFS-A-CK-B05 FS-V-B05 Consumable kit, including O-rings, Silicone tubes and Silicone stopperFS-A-CK-B10 FS-V-B10 Consumable kit, including O-rings, Silicone tubes and Silicone stopperFS-A-CK-B15 FS-V-B15 Consumable kit, including O-rings, Silicone tubes and Silicone stopperFS-A-CK-B20 FS-V-B20 Consumable kit, including O-rings, Silicone tubes and Silicone stopper FS-A-CK-C053 FS-V-C053 Consumable kit, including O-rings, Silicone tubes, Silicone stoppers, Silicone washers, Connector and CapFS-A-CK-C054 FS-V-C054 Consumable kit, including O-rings, Silicone tubes, Silicone stoppers, Silicone washers, Connector and Cap FS-A-CK-D03 FS-V-D03 Consumable kit, including O-ring, Silicone tubes and Silicone stopperFS-A-CK-D05 FS-V-D05 Consumable kit, including O-ring, Silicone tubes and Silicone stopperFS-A-CK-D10 FS-V-D10 Consumable kit, including O-ring, Silicone tubes and Silicone stopper


FS-A-SKproSET Fermentation System Start-up Kit, includes 4 x 250 ml Glass Feeding Bottles, 1 x 500 ml Glass Feeding Bottle, 10 x 45 mm 0.2 μm Autoclavable Disc Type Filters, 15 x Connecting Tubes, 16 x Silicone Tubing Clamps, 25 ft of 1/8 inch (3.2 mm) Silicone Tube, 1 x Handy Burner, 1 x 2 mm Hex Wrench, and 1 x 12 mm & 14 mm Double Open-end Wrench

FS-A-SK20

proSET Parallel Fermentation System Start-up kit, includes8 x 250ml Glass Feeding Bottles, 2 x 500ml Glass Feeding Bottle, 20 x 45mm 0.2μm Autoclavable Disc Type Filters, 30 x Connecting Tubes, 32 x Silicon Tubing Clamps, 2 x 25 ft of 1/8 inch Silicon Tube, 1 x Handy Burner, 1 x 2 mm Hex Wrench, 1 x 12 mm & 14 mm Double Open-end Wrench, and 1 x Crosshead (+) Screwdriver

FS-A-SK01 250 ml Glass Feeding Bottle, Includes Two Stainless Steel Connecting Ports, Cap, and Silicone washerFS-A-SK02 500 ml Glass Feeding Bottle, Includes Two Stainless Steel Connecting Ports, Cap, and Silicone washerFS-A-SK03 45 mm, 0.2 μm Autoclavable Disc Filter, 10 /pkFS-A-SK04 50 mm, 4.5 μm (L) Stainless Steel Connecting Tube, 15 /pkFS-A-SK05 Handy BurnerFS-A-SK06 Silicone Tubing Clamp, 16 /pkFS-A-SK07 2 mm Hex WrenchFS-A-SK08 12 mm & 14 mm Double Open-end WrenchFS-A-SK09 Crosshead(+) ScrewdriverFS-A-SK10 Two stainless steel connecting ports, includes cap and silicone washerMU-S13 Silicone tube, I.D. 1/32”(0.8mm) 25 ft (7.6m)MU-S14 Silicone tube, I.D. 1/16”(1.6mm) 25 ft (7.6m)MU-S16 Silicone tube, I.D. 1/8”(3.1mm) 25 ft (7.6m)MU-S25 Silicone tube, I.D. 3/16”(4.8mm) 25 ft (7.6m)


Silicone Tubing Specifications

Cat. No. CSMU-S13 CSMU-S14 CSMU-S16 CSMU-S25Inner diameter in. (mm) 0.03 (0.8) 0.06 (1.6) 0.12 (3.1) 0.19 (4.8)Hose barb size in. (mm) 1/16 (1.6) 1/16 (1.6) 1/8 (3.2) 3/16 (4.8)Flow range with 6 to 600 rpm drive ml/min

0.36 to 36 1.3 to 130 4.8 to 480 10 to 1000

Maximum pressure, continuous 25 psig (1.7 bar) 20 psig (1.4 bar)Maximum pressure, intermittent 40 psig (2.7 bar) 35 psig (2.4 bar)Maximum vacuum 26” Hg (660 mm Hg)Suction lift 29 ft H2O (8.8m H2O)

Consumable Kit Ordering Information

*For more acid & base resistance silicone tubes, please contact us for more information.*Technical specifications subject to change without notice.


Pilot Scale SIP Fermentation Systems

The proSET brand offers pilot and production scale bioreactor/fermentation systems for all of your large scale fermentation needs. Our standard SIP (sterilization-in-place) system provides top of the line quality and excellent compatibility to meet all the bioprocess engineering standards. All of our features are designed to provide a high level of productivity and automation while maintaining a low operational cost.

Our standard system ranges from 10L to 1000L working volume, which provides a simple yet flexible range of ordering options. Culturing cells and microbes could not be any easier with our full cascade function. In addition, we offer a wide variety of optional devices for all of your fermentation/bio-reaction needs.

Pneumatic valve for accurate control

Detachable aseptic feeding device

Motor lubricate and cooling device

Orbital welding provides top quality

1

1

2

2

3

3

4

4

*For further and updated information, please visit www.cleaverscientific.com

Monitor page for operation overview Real-time controlling interface Auto and manual operation Adjustable pump setting and Cascade control


Pilot Scale SIP Fermentation System 10L / 30L System

Immediate visualization on operation overview

Easy and intuitive operation for manual and sequence control

Online system calibration with system feedback

System expandable with versatile optional devices

One-Touch automatic sterilization for vessel and system tubings

15-Step programmable PID control

Four-staged DO cascade

MotorManual or automatic control of

constant agitation speed

Peristaltic Pump

Stainless Steel VesselSpecial designed heating

jacket provides better

heating efficiency

*All images are reference only, actual products might differ from the pictures above. Cleaver Scientific reserves the right for product revision at any time.

Uses four Watson Marlow

built-in peristaltic pumps for

all your feeding needs

CSFS-30L

CSFS-10L

Control StationLarge screen and graphical user interface


Features

Flexibility• 100L up to 1000L - Capsule Type Vessel• Modular options to fulfill various needs for

different applications• Optional CIP - ready connection ports

Versatility• Colour touch screen control with simple, easy

to use interface• Fully automated process with remote

monitoring• 15-steps automatic program setting• Special coiled jacket design for temperature

uniformity and stability

Sterility• Electropolished tubing and valves, BPE

standard• Orbital welding to ensure minimal residue

buildup• Double-layered mechanical seal with

lubricating water as an indication for breakage

Durability and Safety• SUS316L stainless steel with manual

mechanical control• Outer vessel wall provides thermal insulation

and protection• Exhaust pressure relief valve

Security• Password protection• Multiple users with customized access levels• Multiple built-in safety devices

Production Scale SIP Fermentation System

100L System 500L System1000L System

Fully automatic sterilization process Real-time data trend recording On line system calibration Raw data for service and maintenance

Harvest ValveSingle block valve construction provides superior aseptic harvesting.

Dust-free control cabinet

Head Plate Ports ArrangementSafety devices and extra ports for flexibility.

Stainless Steel VesselHive jacket design provides better heating efficiency.

Piping SystemSUS-316L EP internal polished tubing for parts direct contact with medium

Control Station Large screen and graphical user interface

MotorManual or automatic control of constant agitation speed

Platform(Optional device) For easy access for viewing your experiment, available upon request

Peristaltic PumpBuilt-in three rotors Easy-Load pumps for all your feeding needsA

B

C

D

E

F

G

H

I

I

E

H

I

D

B

A

FG

C

*Please visit our website www.cleaverscientific.com for more product selection and detail information. *Technical specification subject to change without notice.*All images are for reference only, actual products might differ from the pictures above.


SIP Fermentation Systems (Pilot & Production)

SpecificationCapacity 10L 30L 100L 300L 500L 1000LTotal volume 15L 42L 120L 360L 650L 1350LWorking volume 10L 30L 100L 300L 500L 1000LVessel and jacket maximum working pressure

3 barg (43.5 psig) / 4 barg (58 psig) 3 barg (43.5 psig) / 3 barg (43.5 psig)

Type Double layered fully enclosed capsule-type tank, with an outer temperature protective layer

Material Direct contact to medium - SUS316L; all others - SUS304

Surface finishInterior polish ≦ 25 Ra/in (0.6 μm) Mechanical polishing; Electropolish optional Exterior polish ≦ 32 Ra/in (0.8 μm) Mechanical polishing; Electropolish optional

Ports Ports designed according to user requirements

Piping and valve materials

Parts that come in direct contact with the product/medium uses SUS-316L EP (≤25 Ra/in) internal polished tubing (BPE standard) :

A.) Internal EP polished diaphragm type pneumatic valve and manual valve (BPE standard) B.) Tubing all welded with Orbital Welding C.) Vessel bottom drain uses a diaphragm valve, to minimize dead volume D.) Piping designed for ease of transfer to scale up (can be used as a seed fermentation system) or downstream process Parts that do not directly contact product/medium A.) Constructed with SUS304 stainless steel

Controller

10.4” colour industrial touch screen 12” colour industrial touch screen

* User-friendly, graphical control interface * Includes secure user accounts, with different levels of access * Use stainless-steel controller cabinet (100L and above only) * Modularized and standardized design (Module Skid): ergonomically designed according to height, ease of vessel clean up, and ease of extraction in relation to vessel bottom valve * Includes maintenance page with system diagnostics * All programmed setting values are automatically stored into the built-in memory; the settings will not be lost in case of a power outage/interruption. When power is restored, the interrupted process will automatically resumed

Setting* Automated sterilization process * Automated fermentation program * Valve control

DO

* Control Range: 0 - 100%, adjustable* Software electrode calibration, with automatic temperature compensation function * Includes one (1) set of side-inserted stainless steel autoclavable DO electrode* DO stat features with intelligent feeding

pH

* PID control with adjustable deadband * Control range 2.00 to 12.00 pH, ±0.01 * Calibration function with automatic temperature compensation function * Includes one (1) set of side-inserted, autoclavable pH probe with stainless steel housing* pH Stat features with intelligent feeding

Pump

* Built-in peristaltic pumps* Each feeding pump can run an adjustable 15 steps program * Each pump can be adjusted for speed, forward and backward direction, and manual or automatic mode * Each of the four peristaltic pumps can be designated for different functions: acid pump, base pump, antifoam pump, or substrate feeding pump * Optional fifth and six peristaltic pump is also available

Temperature* Vessel temperature is measured with a side-inserted PT-100 temperature probe and maintained using PID control. * Control range: 0-125°C, ±0.1°C. Operational range up to 85°C

*Technical specifications subject to change without notice.

*For system over 1000L please contact the authorized dealer for more details.


Agitation* Manual or automatic control of agitation speed * 15 steps program to change speed, or use DO cascade control

Air supply and exhaust

Gas supply and dehumidifer: uses in-house air compressor or air dehumidifier * Includes re-useable, autoclavable 0.2μm air filter for gas inlet * Gas Inlet (air) Includes mass flow controller: 2 vvm maximum according to the vessel capacity * Gas Inlet (oxygen) Includes pure oxygen rotameter (manual flow control): 1 vvm maximum according to the vessel capacity * Includes oxygen gas solenoid valve, with automatic pulsed time control Air outlet / Exhaust * Exhaust port with stainless steel condenser * Includes re-useable, autoclavable 0.2μm air filter * Includes automated adjustable gas outlet valve to adjust vessel back pressure * Can control manually or automatically via software

Utility Requirement

Capacity 10L 30L 100L 300L 500L 1000L

Power Three phase 220V (note: can be customized to local standard)

Air

At least 6 barg At least 7 barg

30 L/min flow rate

90 L/min flow rate

300 L/min flow rate

900 L/min flow rate

1500 L/min flow rate

3000 L/min flow rate

Dehumidified

Oil-free

Peripheral factory water supply

Cooling water (tap water, at least 15oC below working temperature, must be soft water) ; Pressure at least 2 barg

Process water RO Water

Plant steam ≥ 2 barg

Process steam ≥ 2 barg

DrainIn situ drain;

≥ 1"In situ drain;





≥ 4"

*Customization of the SIP Fermentation system available upon request. Please contact your regional manager for evaluation request.


Model Cylinder Diameter

Cylinder Cubage

CylinderSpeed R.C.F Throughput

CapacityMotorPower Weight Dimension

FS-GQ105 ø105(mm) 6(L) 16000(r/min) 15050(xg) 1.2(T/h) 3(kw) 500(kg) 700x450x1600(mm3)

FS-GQ105B ø105(mm) 6(L) 16000(r/min) 15050(xg) 1.2(T/h) 3(kw) 500(kg) 700x450x1600(mm3)

FS-GQ75 ø75(mm) 2(L) 20000(r/min) 16700(xg) 0.2(T/h) 1.2(kw) 250(kg) 660x390x1200(mm3)

FS-GQ75B ø75(mm) 2(L) 20000(r/min) 16700(xg) 0.2(T/h) 1.2(kw) 250(kg) 660x390x1200(mm3)

High Speed Tubular Centrifuge

Features:• Simple and robust design• Suitable for using corrosive materials• Small footprint• Separation of small particles (to 1um)• High performance• Compact design

Typical Applications:• Separation of viruses and bacteria• Classification of biotechnological solutions• Production of gamma-globulin• Separation and clarification of lubricating oils,

greases and solvents• Concentration of essential oils• Purification of fish oils• Dehydration of varnishes and lacquers• Clarification of fruit juices• Chemical Engineering• Bio-pharmaceutical production


Optional Accessory Items

n Electropolish (EP) of Vessel TankElectropolish of the vessel tank is offered as a higher sanitary grade surface finish. EP surface finish is an addition to the standard mechanical polish (MP) which provides a smoother surface area to minimize residual residue.

*Note that this option MUST be requested at your initial inquiry, later-on additions after the completion of construction is not possible

n Transfer PipingTransfer piping of your resulting product/medium between vessels is offered for convenience of operation. Automated transfer using pressure in addition to directional control with valve regulations offers fast and easy operation.

n Operation PlatformAn operation platform is offered to provide optimal operation convenience. Stainless steel constructed platform offers elevated height for a full observation of the headplate when standing on the platform, the chest-leveled positioning of the vessel headplate prevents falling into the vessel.

*This option is only available with system 200L and above

n CIP Connection ModuleFor automated cleaning procedures, a CIP system may be used with Cleaver Scientific SIP fermentation system. Additional valves, connections, and spray-balls will be installed to allow connection of your own CIP system.

*Note that this option MUST be requested at your initial inquiry, later-on additions after the completion of construction is not possible *This option is only available with system 100L vessel and above.

n Mobile SMS ModuleUse a GSM network to communicate with control unit using SMS text messages (standard fees and charges will apply)

A.) Remotely monitor and control agitation, temperature, DO, and pH *exclusive in Cleaver Scientific

B.) Receive regular updates on fermentation conditions

C.) Receive alarm notifications in fermentation conditions move outside of set range

n Load CellThe load cell provides weighing capability to your fermentation process. Weighing the substrate feeding can indicate how much substrate was added during the fermentation process, which allows the user to provide more accurate control accordingly to what the process needs.

n Cell Density MonitorOur special implemented online cell density device allows you to obtain direct information about your cell growth rate and cell density.These values are critical to many bacterial, yeast and animal cell cultures by combining the monitoring and probing system into one, with high accuracy and easy access, monitoring cell growth is as easy as 1-2-3.

*For further and updated information, please visit www.cleaverscientific.com*Technical specifications subject to change without notice.


n Oxygen Mass Flow ControllerMaintain optimal control over culture DO level by installing this optional mass flow controller. The mass flow controller can accurately adjust the flow rate of incoming oxygen and is resistant to fluctuations in gas pressure, ensuring precise control and repeatibility of experimental conditions

A.) Cascade control scheme

B.) Integrated into controller for simple and automated operation

n CO2 / O2 Off-Gas AnalyzerThe CO2 / O2 Off-Gas Analyzer provides real-time measurements of carbon dioxide and oxygen concentration of the bioreactor exhaust gas. The CO2 concentration is determined using a self-calibrating non-dispersion infrared sensor, while an electrochemical sensor monitors the oxygen concentration. Using this information, the user can continuously monitor metabolism and analyze cell growth parameters.

n ORP ProbeThe ORP probe measures the oxidation-reduction potential of the fermentation media, which is a crucial indicator of anaerobic conditions/reactions. This low/maintenance and sterilizable probe is designed to withstand repeated experiment.

n Turbidity ProbeThe turbidity probe measures the turbidity level of the fermentation media, which provides you an indication for the metabolic reaction and in terms allows you to maintaining a steady cell level.

n Gas Mixing StationThe Gas Mixing Station allows the user to optimize cell growth conditions by independently supplying up to four gasses to the fermentation process. Parameters such as dissolved oxygen and pH can be controlled by adjusting the gas composition supplied to the system. Four manually adjusted flow meters control the flow rate of each gas, while the 4 solenoid valves automatically open or close in response to the culture conditions. The Gas Mixing Station can be operated in either manual or automatic modes.

n Headplate LiftFor SIP vessel headplate lifting, a device for headplate lifting/removal. Chain-hoist system (manual) for 30L; Power-driven (auto) for 100L and above.


Complete proSET Parallel Fermentation System (FS-05 Series) + Mettler Toledo ProbeCat No. Product DescriptionCSFS-05-AS5AS5P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 500mL Double Jacketed Vessel

CSFS-05-AS5A01P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 1L Double Jacketed Vessel




CSFS-05-AS5B01P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 1L Single Wall Dish Bottom Vessel






CSFS-05-AS5C053P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 5L Single Wall Airlfter Vessel

CSFS-05-AS5C054P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 5L Double Jacketed Airlifter Vessel

CSFS-05-AS5D03P Complete proSET Parallel Fermentation System for one 500mL Double Jacketed Vessel and one 3L Single Wall Plain Bottom Vessel



CSFS-05-A01A01P Complete proSET Parallel Fermentation System for one 1L Double Jacketed Vessel and one 1L Double Jacketed Vessel




CSFS-05-A01B01P Complete proSET Parallel Fermentation System for one 1L Double Jacketed Vessel and one 1L Single Wall Dish Bottom Vessel






CSFS-05-A01C053P Complete proSET Parallel Fermentation System for one 1L Double Jacketed Vessel and one 5L Single Wall Airlfter Vessel

CSFS-05-A01C054P Complete proSET Parallel Fermentation System for one 1L Double Jacketed Vessel and one 5L Double Jacketed Airlifter Vessel

CSFS-05-A01D03P Complete proSET Parallel Fermentation System for one 1L Double Jacketed Vessel and one 3L Single Wall Plain Bottom Vessel

















Fermentation System Ordering Information


Complete proSET Parallel Fermentation System (FS-05 Series) + Mettler Toledo Probe

Cat No. Product Description


























CSFS-05-B01B01P Complete proSET Parallel Fermentation System for one 1L Single Wall Dish Bottom Vessel and one 1L Single Wall Dish Bottom Vessel






CSFS-05-B01C053P Complete proSET Parallel Fermentation System for one 1L Single Wall Dish Bottom Vessel and one 5L Single Wall Airlfter Vessel

CSFS-05-B01C054P Complete proSET Parallel Fermentation System for one 1L Single Wall Dish Bottom Vessel and one 5L Double Jacketed Airlifter Vessel

CSFS-05-B01D03P Complete proSET Parallel Fermentation System for one 1L Single Wall Dish Bottom Vessel and one 3L Single Wall Plain Bottom Vessel














Complete proSET Parallel Fermentation System (FS-05 Series) + Mettler Toledo ProbeCat No. Product DescriptionCSFS-05-B05B05P Complete proSET Parallel Fermentation System for one 5L Single Wall Dish Bottom Vessel and one 5L Single Wall Dish Bottom Vessel






























CSFS-05-C053C053P Complete proSET Parallel Fermentation System for one 5L Single Wall Airlifter Vessel and one 5L Single Wall Airlfter Vessel

CSFS-05-C053C054P Complete proSET Parallel Fermentation System for one 5L Single Wall Airlifte Vessel and one 5L Double Jacketed Airlifter Vessel

CSFS-05-C053D03P Complete proSET Parallel Fermentation System for one 5L Single Wall Airlifte Vessel and one 3L Single Wall Plain Bottom Vessel



CSFS-05-C054C054P Complete proSET Parallel Fermentation System for one 5L Double Jacketed Airlifter Vessel and one 5L Double Jacketed Airlifter Vessel

CSFS-05-C054D03P Complete proSET Parallel Fermentation System for one 5L Double Jacketed Airlifter Vessel and one 3L Single Wall Plain Bottom Vessel

CSFS-05-C054D05P Complete proSET Parallel Fermentation System for one 5L Double Jacketed Airlifter Vessell and one 5L Single Wall Plain Bottom Vessel

CSFS-05-C054D10P Complete proSET Parallel Fermentation System for one 5L Double Jacketed Airlifter Vessel and one 10L Single Wall Plain Bottom Vessel

CSFS-05-D03D03P Complete proSET Parallel Fermentation System for one 3L Single Wall Plain Bottom Vessel and one 3L Single Wall Plain Bottom Vessel







Complete proSET One Fermentation System (FS-06 Series) + Hamilton ProbeCat No. Product DescriptionCSFS-06-AS5P-110 Complete proSET One Fermentation System for 500ml Double Jacketed Vessel, 110VCSFS-06-AS5P-220 Complete proSET One Fermentation System for 500ml Double Jacketed Vessel, 220VCSFS-06-A01P-110 Complete proSET One Fermentation System for 1L Double Jacketed Vessel, 110V

CSFS-06-A01P-220 Complete proSET One Fermentation System for 1L Double Jacketed Vessel, 220V







CSFS-06-B01P-110 Complete proSET One Fermentation System for 1L Single Wall Dish Bottom Vessel, 110V








CSFS-06-C053P-110 Complete proSET One Fermentation System for 5L Single Wall Airlifter Vessel, 110V

CSFS-06-C053P-220 Complete proSET One Fermentation System for 5L Single Wall Airlifter Vessel, 220V

CSFS-06-C054P-110 Complete proSET One Fermentation System for 5L Double Jacketed Airlifter Vessel, 110V

CSFS-06-C054P-220 Complete proSET One Fermentation System for 5L Double Jacketed Airlifter Vessel, 220V

CSFS-06-D03P-110 Complete proSET One Fermentation System for 3L Single Wall Plain Bottom Vessel with Heating Base Unit, 110V






CSFS-06-EPM-110proSET One expansion 110V module, expand system compatibility to Oxygen enrichment module, Gas mixing station, Photo-biosynthesis module and ORP probe.

CSFS-06-EPM-220proSET One expansion 220V module, expand system compatibility to Oxygen enrichment module, Gas mixing station, Photo-biosynthesis module and ORP probe.


Complete proSET Evo System (FS-07 Series) + Mettler Toledo ProbeCat No. Product DescriptionCSFS-07-AS5P-110 Complete proSET Evo Fermentation System for 500mL Double Jacketed Vessel, 110V

CSFS-07-AS5P-220 Complete proSET Evo Fermentation System for 500mL Double Jacketed Vessel, 220V

CSFS-07-A01P-110 Complete proSET Evo Fermentation System for 1L Double Jacketed Vessel, 110V








CSFS-07-B01P-110 Complete proSET Evo Fermentation System for 1L Single Wall Dish Bottom Vessel, 110V

CSFS-07-B01P-220 Complete proSET Evo Fermentation System for 1L Single Wall Dish Bottom Vessel 220V


CSFS-07-B03P-220 Complete proSET Evo Fermentation System for 3L Single Wall Dish Bottom Vessel 220V









CSFS-07-C053P-110 Complete proSET Evo Fermentation System for 5L Single Wall Air Lifter Vessel, 110V

CSFS-07-C053P-220 Complete proSET Evo Fermentation System for 5L Single Wall Air Lifter Vessel, 220V

CSFS-07-C054P-110 Complete proSET Evo Fermentation System for 5L Double Jacketed Air Lifter Vessel, 110V

CSFS-07-C054P-220 Complete proSET Evo Fermentation System for 5L Double Jacketed Air Lifter Vessel, 220V

CSFS-07-D03P-110 Complete proSET Evo Fermentation System for 3L Single Wall Plain Bottom Vessel, 110V






Complete proSET Solid State Fermentation SystemCat No. Product DescriptionCSFS-10-A05P-110 Complete proSET Solid State Fermentation System for 5L Double Jacketed Vessel, 110VCSFS-10-A05P-220 Complete proSET Solid State Fermentation System for 5L Double Jacketed Vessel, 220V


1. Business customers and consumers1.1 Some of these terms apply to consumers only; some apply to business customers only. Those

terms are marked as such.1.2 All other terms apply to all customers.1.3 Youareclassifiedasabusinesscustomerifyouindicatetousthatthegoodssuppliedby

uswillbeusedinthecourseofyourbusinessorifyouusethegoodsinthecourseofyourbusiness.

1.4 Ifyouarenotabusinesscustomer,youareaconsumer.Nothinginthesetermsaffectsyourstatutoryrightsasaconsumer.

2. Price2.1 Consumers: The quoted price includes VAT (unless otherwise stated).2.2 Business customers: The price quoted excludes VAT (unless otherwise stated). VAT will be

chargedattherateapplyingatthetimeofdelivery.2.3 Ourquotationslapseaftertwelveweeks(unlessotherwiseagreed).2.4 Business customers:Thepricequotedexcludesdelivery(unlessotherwisestated).2.5 Business customers: Unless otherwise stated, the price quoted to business customers is an

illustrativeestimateonlyandthepricechargedwillbeourpricecurrentatthetimeofdelivery.2.6 Business customers: Ratesoftaxanddutiesonthegoodswillbethoseapplyingatthetime

ofdelivery.2.7 Business customers: Atanytimebeforedeliverywemayadjustthepricetoreflectany

increaseinourcostsofsupplyingthegoods.3. Delivery3.1 Alldeliverytimesquotedareestimatesonly.3.2 Ifwefailtodeliverwithinareasonabletime,youmay(byinformingusinwriting)cancelthe

contract,however:3.2.1 youmaynotcancelifwereceiveyournoticeafterthegoodshavebeendispatched;and3.2.2 ifyoucancelthecontract,youcanhavenofurtherclaimagainstusunderthatcontract.3.3 Ifyouacceptdeliveryofthegoodsaftertheestimateddeliverytime,itwillbeonthebasisthat

youhavenoclaimagainstusfordelay(includingindirectorconsequentialloss,orincreaseinthepriceofthegoods).

3.4 Wemaydeliverthegoodsininstalments.Eachinstalmentistreatedasaseparatecontract.4 Delivery and safety 4.1 Wemaydeclinetodeliverif:4.1.1 webelievethatitwouldbeunsafe,unlawfulorunreasonablydifficulttodoso;or4.1.2 thepremises(ortheaccesstothem)areunsuitableforourvehicle.5 Payment terms5.1 Youaretopayuscash(orotherwiseinclearedfundssuchasbycreditcard)ondelivery

unlessyouhaveanapprovedcreditaccount.5.2 Business customers: IfyouhaveanapprovedUKbusinesscreditaccount,paymentisdue

30daysfromtheendofthemonthoftheinvoice,unlessotherwiseagreedinwriting.5.3 If you fail to pay us in full on the due date:5.3.1 wemaysuspendorcancelfuturedeliveries;5.3.2 we may cancel any discount offered to you;5.3.3 youmustpayusinterestattherateequivalenttothatsetforthepurposesofs6oftheLate

Payment of Commercial Debts (Interest) Act 1998:a. calculated(onadailybasis)fromthedateofourinvoiceuntilpayment;b. compoundedonthefirstdayofeachcalendarmonth;andc. beforeandafteranyjudgement(unlessthecourtordersotherwise).5.4 Ifyouhaveanapprovedbusiness credit account we may withdraw it or reduce your credit

limitorbringforwardyourduedateforpayment.5.5 We take any of those actions in 5.4 at any time and without notice.5.6 Youdonothavetherighttosetoffanymoneyyoumayclaimfromusagainstanythingyou

may owe us.5.7 Whileyouowemoneytous,wehavearighttokeepanypropertywemayholdofyoursuntil

youhavepaidusinfull(alien).5.8 You are to indemnify us in full and hold us harmless from all expenses and liabilities we may

incur(directlyorindirectlyandincludinglegalcostsonafull indemnitybasis)followinganybreachbyyouofanyofyourobligationsundertheseterms.

6 Title 6.1 Consumers: s18 Sale of Goods Act 1979 applies. 6.2 Business customers: Until you pay all debts you may owe us: 6.2.1 allgoodssuppliedbyusremainourproperty;6.2.2 youmuststorethemsothattheyareclearlyidentifiableasourproperty;6.2.3 youmustinsurethem(againsttherisksforwhichaprudentownerwouldinsurethem)and

hold the policy on trust for us;6.2.4 youmayusethosegoodsandsellthemintheordinarycourseofyourbusiness,butnotif:a. werevokethatright(byinformingyouinwriting);orb. youbecomeinsolvent.6.3 Business customers: Youmustinformus(inwriting)immediatelyifyoubecomeinsolvent.6.4 Business customers: Ifyourrighttouseandsell thegoodsendsyoumustallowusto

removethegoods.6.5 Business customers: Wehaveyourpermissiontoenteranypremiseswherethegoodsmay

be stored:6.5.1 at any time, to inspect them; and6.5.2 afteryourrighttouseandsellthemhasended,toremovethem,usingreasonableforceif

necessary.6.6 Despiteourretentionof titletothegoods,wehavetheright totakelegalproceedingsto

recoverthepriceofgoodssuppliedshouldyounotpayusbytheduedate.6.7 Youarenotouragent.Youhavenoauthoritytomakeanycontractonourbehalforinour

name.7 Risk7.1 Thegoodsareatyourriskfromthetimeofdelivery.7.2 Deliverytakesplaceeither:7.2.1 atourpremises(ifyouarecollectingthemorarrangingcarriage);or7.2.2 atyourpremises(ifwearearrangingcarriage).7.3 Youmustinspectthegoodsondelivery.Ifanygoodsaredamaged(ornotdelivered),you

mustwritetotelluswithinsevenworkingdaysofdelivery(ortheexpecteddeliverytime).Youmustgiveus(andanycarrier)afairchancetoinspectthedamagedgoods.

8 Warranties8.1 Wewarrantthatthegoods:8.1.1 complywiththeirdescriptiononourdeliverynote;and8.1.2 arefreefrommaterialdefectatthetimeofdelivery(aslongasyoucomplywithclause7.3).8.2 Business customers:Wegivenootherwarranty (andexcludeanywarranty, termor

conditionthatwouldotherwisebeimplied)astothequalityofthegoodsortheirfitnessforanypurpose.

8.3 Consumers: Yourstatutoryrightsareunaffected.8.4 Ifyoubelievethatwehavedeliveredgoodswhicharedefectiveinmaterialorworkmanship,

you must:8.4.1 informus(inwriting),withfulldetails,assoonaspossible;and8.4.2 allowustoinvestigate(wemayneedaccesstoyourpremisesandproductsamples).8.4.3 Ifthegoodsarefoundtobedefectiveinmaterialorworkmanship(followingourinvestigations),

andyouhavecompliedwiththoseconditions(inclause8.4) infull,wewill(atouroption)replacethegoodsorrefundtheprice.

8.5 Wearenot liableforanyother lossordamage(includingindirectorconsequential loss,financialloss,lossofprofitsorlossofuse)arisingfromthecontractorthesupplyofgoodsortheiruse,evenifwearenegligent.

8.6 Ourtotal liability toyou(fromonesinglecause)fordamagetoproperty is limitedtofivemillion pounds.

8.7 For all other liabilities not referred to elsewhere in these terms our liability is limited in damagestothepriceofthegoods.

8.8 Nothinginthesetermsrestrictsorlimitsourliabilityfordeathorpersonalinjuryresultingfromnegligence.

9 Specificationsanddesigns9.1 Ifwepreparethegoodsinaccordancewithyourspecificationsorinstructions:9.1.1 youmustensurethatthespecificationsorinstructionsareaccurate;9.1.2 youmustensurethatgoodspreparedinaccordancewiththosespecificationsorinstructions

willbefitforthepurposeforwhichyouintendtousethem;and9.1.3 youwarrantthatthespecificationsordesignswillnotresultintheinfringementofanyrights

belongingtoathirdpartyandthatyouwillindemnifyusinrespectofallloss,damage,costsorexpenses(includinglegalfees)whichwemayincurinconnectionwithanysuchclaimorthreatened claim by a third party.

9.2 Bysupplyinggoodstoyouwedonotwaiveanyintellectualpropertyrights(includinganydesignrights)thatwemayhaveinrespectofthem.

9.3 Business customers only:wealsoreservetheright tomakewithoutnoticeanyminormodificationsinourspecificationsdesignsormaterialsaswethinknecessaryordesirable.

9.4 Wereservetherighttomakeanychangesinthespecificationsanddesignsofourgoodswhich are necessary to ensure they conform with any applicable safety or other statutory requirements.

10 Returnofgoods10.1 Wewillacceptthereturnofgoodsfromyouonly:10.1.1 bypriorarrangement(confirmedinwriting);10.1.2 onpaymentofanagreedhandlingcharge(unlessthegoodsweredefectivewhendelivered);

and10.1.3 wherethegoodsareasfitforsaleontheirreturnastheywereondelivery.11 Export terms11.1 WherethegoodsaresuppliedbyustoyoubywayofexportfromtheUnitedKingdomthen

the ‘Incoterms’ of the International Chamber of Commerce which are in force at the time of the date when the contract is made shall apply.

11.2 IfthereisanyconflictbetweentheIncotermsandthetermsinthesetermsoftradingthenthesetermsshallprevail.

11.3 Clause11ofthesetermsshallapplytoexports(exceptwhereotherwiseagreedinwritingbetweenus)notwithstandinganyotherprovisionsoftheseterms.

11.4 Youare responsible forcomplyingwithany legislationor regulationsgoverning theimportationofthegoodsintothecountryofdestinationandforthepaymentofanydutiesdue.

11.5 Thegoodsshallbedeliveredasagreedbetweenusbutweshallbeundernoobligationtogiveanoticeundersection32(3)oftheSaleofGoodsAct1979.

11.6 Youhavetherightatyourexpenseandbyarrangementwithustoinspectthegoodsatourpremisesoratthepointofshipmentbeforeshipmentexceptwhereotherwiseagreed. Ifyoudonotexercisethatrightthenthefactthegoodspassedourqualityinspectionwillbeconclusiveproofthattheywereofthewarrantedquality.Wearenot liableforanydefectinthegoodswhichwouldbeapparentonyour inspectionunlessaclaimismadebeforeshipment.Wearenotliableforanydamageduringtransit.

11.7 Paymentofallamountsduetousshallbemadeasstipulatedbyusunlessotherwiseagreedinwriting.

11.8 WeshallhavenoliabilityfordeathorpersonalinjuryarisingfromtheuseofthegoodswherethegoodsaretobedeliveredintheterritoryofanotherState(withinthemeaningofs.26(3)(b) Unfair Contract Terms Act 1977).

12 Cancellation12.1 Suppose the order is cancelled (for any reason). You are then to pay us for all stock

(finishedorunfinished)wemaythenhold(ortowhichwearecommitted)fortheorder.12.2 We may suspend or cancel the order, by written notice if:12.2.1 you fail to pay us any money when due (under the order or otherwise);12.2.2 youbecomeinsolvent;12.2.3 youfailtohonouryourobligationsundertheseterms.12.3 Youmaynotcanceltheorderunlessweagreeinwriting(andclauses3.2.2and10.1then

apply).13 Waiver and variations13.1 Anywaiverorvariationofthesetermsisbindinginhonouronlyunless:13.1.1 made(orrecorded)inwriting;13.1.2 signedonbehalfofeachparty;and13.1.3 expresslystatinganintentiontovarytheseterms.13.2 All orders that you place with us will be on these terms (or any that we may issue to replace

them).Byplacinganorderwithus,youareexpresslywaivinganyprintedtermsyoumayhavetotheextentthattheyareinconsistentwithourterms.

14 Force majeure - business customers only14.1 Supposeweareunabletoperformourobligationstoyou(orabletoperformthemonlyat

unreasonable cost) because of circumstances beyond our control. We may then cancel or suspendanyofourobligationstoyou,withoutliability,

14.2 Examplesof thosecircumstances includeactofGod,accident,explosion,fire, transportdelays,strikesandotherindustrialdisputesanddifficultyinobtainingsupplies.

15 General15.1 EnglishlawisapplicabletoanyContractmadeundertheseterms.TheEnglishandWelsh

courtshavenon-exclusivejurisdiction.15.2 Ifyouaremorethanoneperson,eachofyouhasjointandseveralobligationsunderthese

terms15.3 If any of these terms are unenforceable as drafted:15.3.1 it will not affect the enforceability of any other of these terms; and15.3.2 if it would be enforceable if amended, it will be treated as so amended.15.4 Wemaytreatyouasinsolventif:15.4.1 you are unable to pay your debts as they fall due; or15.4.2 you(oranyitemofyourproperty)becomesthesubjectof:a. any formal insolvencyprocedure (examplesofwhich includereceivership, liquidation,

administration,voluntaryarrangements{includingamoratorium}orbankruptcy);b. anyapplicationorproposalforanyformalinsolvencyprocedure;orc. anyapplication,procedureorproposaloverseaswithsimilareffectorpurpose.15.5 Business customers: allbrochures,cataloguesandotherpromotionalmaterialsaretobe

treatedasillustrativeonly.Theircontentsformnopartofanycontractbetweenusandyoushouldnotrelyontheminenteringintoanycontractwithus.

15.6 Business customers only:anynoticebyeitherofuswhichistobeservedunderthesetermsmaybeservedbyleavingitatorbydeliveringitto(byfirstclasspostorbyfax)theother’sregisteredofficeorprincipalplaceofbusiness.Allsuchnoticesmustbesigned.

15.7 Nocontractwillcreateanyrightenforceable(byvirtueof theContracts [RightsofThirdParties]Act1999)byanypersonnotidentifiedasthebuyerorseller.

15.8 Theonlystatementsuponwhichyoumayrely inmakingthecontractwithus,arethosemadeinwritingbysomeonewhois(orwhomyoureasonablybelievetobe)ourauthorisedrepresentativeandeither:

15.8.1 containedinourestimate(oranycoveringletter)andnotwithdrawnbeforethecontractismade; or

15.8.2 whichexpresslystatethatyoumayrelyonthemwhenenteringintothecontract.15.9 Nothinginclause15.8istoaffectorlimitourliabilityforfraudulentmisrepresentation.

CLEAVER SCIENTIFIC TERMS AND CONDITIONS

www.cleaverscientific.com

Cleaver Scientific LtdUnit 41,Somers Road Industrial Estate,Rugby, CV22 7DHUnited Kingdom

t: +44 (0)1788 565300f: +44 (0)1788 552822

[email protected]

Distributor

proset fermentation 2016/17 catalogue · all about proset fermentation and cell cultivation system...

Documents