programa microbiomas
TRANSCRIPT
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7/31/2019 Programa Microbiomas
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Doctorado en Ciencias Mencin Microbiologa
Microbiomas
Temas- Holobionte &
Hologenomas
- Simbiontes en plantas y
lquenes
- Sexo en Artrpodos
- Animales gnotobiticos
- Microbioma humano
- Disbiosis & otras
enfermedades
- Antibiticos y
Probiticos
- Microbioma &
inmunidad
- Biotecnologas del
microbioma
ProfesoresDr. Francisco P. Chvez (FCH)Dr. Alvaro Glavic (AG)Dra. Julieta Orlando (JO)Dr. Elias Utreras (EU)Lic. Javiera Ortiz-Severn (JOS)
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7/31/2019 Programa Microbiomas
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7/31/2019 Programa Microbiomas
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Doctorado en Ciencias Mencin Microbiologa
Simbiosis en lquenes y plantas
1. The rhizosphere microbiome and plant health. Trends in Plant Science (2012) doi:10.1016/j.tplants.2012.04.001
2. Deciphering the rhizosphere microbiome for disease-suppressive bacteria. Science(2011), doi:10.1126/science.1203980.
3. Photoautotrophic symbiont and geography are major factors affecting highlystructured and diverse bacterial communities in the lichen microbiome. Environ Microbiol . (2012), doi:10.1111/j.1462-2920.2011.02560.x
Wolbachia & desarrollo en insectos
1. Wolbachia - master manipulators of invertebrate biology. Nature Rev. Microbiol. (2008) doi:10.1038/nrmicro1969.
2. Wolbachia enhance Drosophila stem cell proliferation and target the germline stemcell niche. Science (2011), doi:10.1126/science.1209609.
3. A Wolbachia symbiont in Aedes aegypti limits infection with Dengue, Chikungunya,and Plasmodium . Cell (2009), doi:10.1016/j.cell.2009.11.042.
Microbiomas en el desarrollo y la evolucin en Drosophila
1. Drosophila microbiome modulates host developmental and metabolic homeostasisvia Insulin signaling. Science (2011), doi:10.1126/science.1212782.
2. Commensal bacteria play a rol in mating preferences of Drosophila melanogaster.PNAS (2010), doi:10.1073/pnas.1009906107.
Microbiomas & Animales gnotobiticos.
1. Reciprocal gut microbiota transplants from zebrafish and mice to germ-freerecipients reveal host habitat selection. Cell (2006), doi:10.1016/j.cell.2006.08.043.
2. Creating and characterizing communities of human gut microbes in gnotobioticmice. The ISME Journal (2010) doi:10.1038/ ismej.2010.110.
3. Extensive personal human gut microbiota culture collections characterized andmanipulated in gnotobiotic mice. PNAS (2011), doi:10.1073/pnas.1102938108.
Referencias
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7/31/2019 Programa Microbiomas
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Doctorado en Ciencias Mencin Microbiologa
Proyecto del microbioma humano.
1. The human microbiome: our second genome. Annu. Rev. Genomics Hum. Genet .(2012), doi:10.1146/annurev-genom-090711-163814.
2. Enterotypes of the human gut microbiome. Nature (2012), doi:10.1038/ nature09944.
3. Human gut microbiome viewed across age and geography. Nature (2012), doi:10.1038/nature11053.
Microbioma vaginal y durante el embarazo.
1. Complexities of the uniquely human vagina. Sci. Transl. Med. (2012), doi:10.1126/ scitranslmed.3003944.
2. Temporal dynamics of the human vaginal microbiota. Sci. Transl. Med. (2012), doi:10.1126/scitranslmed.3003605.
3. Host remodeling of the gut microbiome and metabolic changes during pregnancy.Cell (2012), doi:10.1016/j.cell.2012.07.008.
Microbioma oral y de la piel
1. Deep sequencing of the oral microbiome reveals signatures of periodontal disease.PLoS ONE (2012)doi:10.1371/journal.pone.0037919.
1. Topographical and temporal diversity of the human skin microbiome. Science (2009), 10.1126/science.1171700.
2. Composition of human skin microbiota affects attractiveness to malaria mosquitoes.PLoS ONE (2011) doi:10.1371/journal.pone.0028991.
Microbioma & obesidad
1. An obesity-associated gut microbiome with increased capacity for energy harvest.Nature (2006), doi:10.1038/nature05414.
2. Diet-induced obesity is linked to marked but reversible alterations in the mousedistal gut microbiome. Cell Host & Microbe (2008) doi:10.1016/j.chom.2008.02.015.
3. A core gut microbiome in obese and lean twins. Nature (2009), doi:10.1038/ nature07540.
Referencias
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7/31/2019 Programa Microbiomas
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Doctorado en Ciencias Mencin Microbiologa
Biotecnologa de microbiomas.
1. Unraveling how probiotic yogurt works Sci. Transl. Med. (2011) doi:10.1126/ scitranslmed.3003291.
2. The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci. Transl. Med. (2011), doi:10.1126/ scitranslmed.3002701.
3. Testing a role for the intestinal microbiome in human obesity. Sci. Transl. Med .(2009) doi:10.1126/scitranslmed.3000483.
4. The effect of diet on the human gut microbiome: a metagenomic analysis inhumanized gnotobiotic mice. Sci. Transl. Med. (2009), doi:10.1126/scitranslmed.3000322.
Microbioma & Sistema inmune.1. Has the microbiota played a critical role in the evolution of the adaptive immune
system? Science (2010), doi:10.1126/science.1195568.
2. The Toll-Like receptor 2 pathway establishes colonization by a commensal of thehuman microbiota. Science (2012) doi:10.1126/science.1225152.
3. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmunedemyelination. Nature (2011), doi:10.1038/nature10554.
Ecologa y evolucin del microbioma.
1. The application of ecological theory toward an understanding of the humanmicrobiome. Science (2012), doi:10.1126/science.1224203.
2. Worlds within worlds: evolution of the vertebrate gut microbiota. Nat. Rev.Microbiol. (2008), doi:10.1038/nrmicro1978
3. Diet drives convergence in gut microbiome functions across mammalian phylogenyand within humans. Science (2011), doi:10.1126/science.1198719.
Referencias