professional development programme for organ donation professor david price dr chris danbury 2...

Professional Development Programme for Organ Donation

Professor David PriceDr Chris Danbury

2 February 2009

“Improving organ donation within your hospital”

Law and Donation Masterclass“Best Interest is Best Practice”


‘Urgent attention is required to resolve outstanding legal, ethical and professional issues in order to ensure that all clinicians are supported and able to work within a clear and

unambiguous framework of good practice. Additionally, an independent UK-wide Donation Ethics Group should be established.’

What does the taskforce say about organs for transplants ethical, legal and professional issues?

2

Recommendation 3 of the Organ Taskforce states:


• To deliver an adequate understanding of the legal frameworks that support deceased organ donation in the UK

• To ensure that the option of organ donation is not denied to a patient or their family through lack of knowledge or misunderstanding of these legal frameworks

• To develop the skills that will be required to introduce and expand local organ donation programmes that are based upon the evolving and broadening interpretation of ‘best interests’ in the UK

• To appreciate how an expanded definition of best interests may permit donation in other circumstances where a patient is dying but not yet dead

What are the objectives of this Masterclass?

3


Agenda

1 Aspects of the law relevant to organ and tissue donation 10 minutes

2 The law governing end-of-life care 30 minutes

3 Application of governmental guidelines on Non-Heart Beating Donation into clinical practice

30 minutes

4 Case studies and Q&A 35 minutes

4

Professional Development Programme for Organ Donation5

Issues to be covered

1 Clarification of the laws governing deceased organ and tissue donation

2 Clarification of the laws governing end-of-life care

3 Understanding the impact of the law on potential organ donation and end-of-life care

4 Understanding the concept of best interest and how it can be applied

5

Aspects of Law relevant to Organ and Tissue Donation

Professor David Price

6


What are the legal authorities governing Organ Donation?

• Statutes

• Statutory Instruments

• EU Directives

• Human Rights Act 1998 (European Convention on Human Rights)

• Judge-made (Common) Law

There are 5 core legal authorities which govern organ donation:


What are the statutory jurisdictions?

England & Wales

• Human Tissue Act 2004

• Mental Capacity Act 2005

Northern Ireland

• Human Tissue Act 2004

Scotland

• Human Tissue (Scotland) Act 2006

• Adults with Incapacity (Scotland) Act 2000

The statutory jurisdictions governing organ donation differ across countries in the UK


What areas of Organ Donation are dealt with through the Law?

Laws which govern Organ Donation primarily focus on removal of tissue from cadavers and end of life care.

Organ Donation Process Addressed by which law

Removal of tissue and organ from a cadaver Governed by statute law (Human Tissue Acts)

1) Removal of organs and tissue:

Organ Donation Process Addressed by which law

Law relating to consent to medical treatment Common Law: UK generally

Test for decision-making capacity and best interests

Mental Capacity Act 2005: England & Wales

Adults with Incapacity Act 2000: Scotland

Common law: Northern Ireland

2) End of life care:

Laws governing removal of organs and tissue

Human Tissue Act 2004Human Tissue (Scotland) Act 2006

10


What is the relevant law in England, Wales and Northern Ireland?

“Governs the removal, storage and use of organs and tissues from deceased persons for the purposes of transplantation. No licence is required from the Human Tissue Authority for

storage where it is an organ or part of an organ or where it is stored for less than 48 hours”

Human Tissue Act, 2004

[ Reg 3, SI 2006 No. 1260]

Human Tissue Act (2004) specifically uses the term ‘consent’, even when this is given by families.

Human Tissue Act (2004) addresses the removal of organ and tissue from cadavers


For adults

•If a decision of a deceased person to consent to the activity, or a decision of his not to consent to it, was in force immediately before he had died, his consent

•Where such a decision is not in force, consent is required from a nominated representative or a person in a qualifying relationship (such as next of kin)

•No particular form for consent is specified

For minors

•The consent of the (competent) minor

•Where no decision was made prior to death or the minor was not competent to deal with the issue it is the consent of a person with parental responsibility

•If there is no person with parental responsibility it is the consent of a ‘qualifying relative’

Who can give consent for donation?

As applied in NI, Wales and England

Introductory line...

12


If no decision is made, how can consent be given?

As applied in NI, Wales and England

Nominated Representatives: (high-level description required)

Qualifying Relatives: (high-level description required)

• One or more persons

• Made orally in the presence of two witnesses or in

writing either:

Signed in the presence of at least one witness

At his direction and in his presence and in the presence

of at least one witness

Made in a will

• Spouse or partner

• Parent or child

• Brother or sister

• Grandparent or grandchild

• Niece or nephew

• Stepfather or stepmother

• Half brother or sister

• Friend of long-standing

Introductory line...


What is the relevant law in Scotland?

As applied in Scotland

• Uses the concept of ‘authorisation’ rather than ‘consent’

• General donation framework similar to rest of UK

• Different provisions relating to 16 year olds and 12-16 year olds

Key message from slide – eg. The Human Tissue Act in Scotland applies a different principle to that which is used in the rest of the UK

Human Tissue (Scotland) Act addresses the removal of organ and tissue from cadavers


What does ‘authorisation’ mean in Scotland?


• Authorisation may be given by the adult person or, where no such authorisation has been given, by the adult’s nearest relative

• The nearest relative may not give authorisation if he or she has actual knowledge that the person was unwilling that the body (or the relevant part) be used for transplantation

• Authorisation may be in writing or expressed verbally (and signed in the case of a nearest relative)

Key message from slide – eg. xxx

Authorisation is xxx


If no decision is made, how can authorisation be given in Scotland?


1. Spouse or civil partner

2. Living with the adult as husband or wife or in a relationship which had the characteristics of the relationship between civil partners and had been so living for not less than 6 months;

3. Child

4. Parent

5. Brother or sister

6. Grandparent

7. Grandchild

8. Uncle or aunt

9. Cousin

10. Niece or nephew

11. A friend of longstanding of the adult

Qualifying Relatives for Adults in Scotland

The table below highlights the qualifying relatives for adults in Scotland

The Law Governing End-of-life CareDecision Making Powers

17


Who has decision making powers in end-of-life care?

Patient competent (Y/N)?

Legal authorities have decision making power

Patient has decision making power

England & Wales

ScotlandNorthern Ireland

Welfare Attorney

Guardian

Intervener

Clinician

Court of Session

Court

Clinician

The chart below shows the decision making process for end-of-life care

YES NO

Decision making powers in end-of-life care vary across countries in the UK

Lasting Power of Attorney

Court Appointed by Deputy

Court of Protection

Clinician or Carer


How does the Law in England and Wales define competence?

Introductory sentence – eg. The Mental Capacity Act 2005 ...

•A person is assumed to possess capacity unless it is established otherwise

•All practicable steps should be taken to facilitate decision-making capacity

•All acts done, or decisions made, for a person lacking capacity must be done or made in the person’s best interests

As applied in Wales and England


Adults with Incapacity (Scotland) Act 2000

“[T]he medical practitioner primarily responsible for the medical treatment of the adult shall have, during the period specified in the certificate, authority to

do what is reasonable in the circumstances, in relation to the medical treatment, to safeguard or promote the physical or mental health of the adult”

Section 47(2)

“There shall be no intervention in the affairs of an adult unless the person responsible for authorising or effecting the intervention is satisfied that the

intervention will benefit the adult and that such benefit cannot reasonably be achieved without the intervention”

Section 1(2)

‘In determining if an intervention is to be made, account must be taken of, amongst other things,the present and past wishes and feelings of the adult so

far as they can be ascertained by any means of communication, whether human or by mechanical aid (whether of an interpretative nature or otherwise)

appropriate to the adult’

Section 1(4)

How does the Law in Scotland define competence?

Key message from slide – xxxThe issue of capacity in Scotland is defined in relation to incapacity

Introductory sentence – eg The issue of capacity in Scotland is defined in relation to incapacity


Best Interests

Assessing Best Interests

21


What is ‘best interests’?

When a person no longer has decision making capacity, decisions must be made in their best interests

Best interest can be defined as:

•It is the patient’s interests only that count

•The decision will be a function of all the circumstances of the individual case

•Best interests includes reference to all factors affecting the person’s interests and in particular the person’s past and present wishes

David, can you review sub-title sentence


How is the term best interest defined?

Introductory sentence – eg Common law has further determined that a person’s best interests must account for the range of interests which a person has

“best interests encompasses medical, emotional and all other welfare issues”

Dame Butler-Sloss in In re A (Medical Treatment: Male Sterilisation) [2000]

What ‘other interests’ are there?

Emotional Spiritual Psychological Altruistic Welfare


How is the principle of ‘best interests’ safeguarded?

Introductory sentence, eg. The Mental Capacity Act 2005...

•Must consider, as far as is reasonably ascertainable… The person’s past and present wishes and feelings (and in particular any relevant

written statement made when he had capacity)

The beliefs and values that would be likely to influence his decision if he had capacity

The other factors that he would be likely to consider if he were able to do so


What potential harm does this prevent?

Introductory sentence...

•Worsening of the patient’s medical condition

•Shortening of the patient’s life

•Pain from an invasive procedure

•Distress to family and friends

The Law in Practice

Applying the principles to specific scenarios

26


How has the principle of best interest been supported by the law?

Case law has established that a life support system can not lawfully be administered if it is not in the best interests of the patient

Airedale NHS Trust v Bland [1993]

‘[I]f there comes a stage where the responsible doctor comes to the reasonable conclusion (which accords with the views of a responsible body of medical

opinion) that further continuance of an intrusive life support system is not in the best interests of the patient, he can no longer lawfully continue that life support system: to do so would constitute the crime of battery and the tort of trespass to

the person’

[Lord Browne-Wilkinson]

General NoteAre there any key points to highlight as background to the case?


In which instance has the broad definition of best interest been applied?

Introductory sentence – xxx

Ahsan v UHL NHS Trust [2007]

• Patient was in a persistent vegetative state

• Clinicians believed patient was better cared for in hospital

• Court allowed patient to be taken home as this was more consistent with her spiritual beliefs


What are the specific scenarios impacted by Organ Donation Law (1/2)?

Elective Ventilation

• Initiation of ‘futile’ life-supporting ventilation

• Allegedly not in the patient’s best interests

• Only best medical interests considered

• No account taken of the person’s wishes regarding organ donation

• Different approach today where the person wished to be an Organ Donor

Life-Prolonging Treatments

Introduction of new therapies e.g. •Inotropic or cardio-respiratory support•Venous cannulae

Adjustments to existing treatments e.g. •Increases in oxygen concentration•Alterations to rates of fluids or drugs or•Ventilation settings, etc•The individual’s best interest

There are 4 key specific scenarios impacted by organ donation law:


What are the specific scenarios impacted by Organ Donation Law (2/2)?

Blood Sampling

• Removing blood from a patient who lacks capacity must be in their best interests

• Stored whole blood or serum may be tested for the purposes of transplantation where this is in the patient’s best interests

• The person’s desire to be an organ donor would be a relevant factor in determining if either of the above was in the individual’s best

More Invasive Interventions

• No procedure which will hasten the patient’s death may be administered in the interests of organ donation

• Procedures that place the individual at risk of serious harm (e.g. systematic heparinisation; resuscitation; femoral cannulation) are unlikely ever to be in a patient’s best interests

There are 4 key specific scenarios impacted by organ donation law:

Application of governmental guidelines on Non-Heart Beating Donation into clinical practiceDr Chris Danbury

31


What are the duties of a doctor when it comes to life and death?

Life is sacred

Biophysicists have been able to comment on the nature and qualities of life forms:

•Life forms function on negative entropy

•They are able to decrease their internal entropy at the expense of substances or free energy taken in from the environment and subsequently rejected in a degraded form

As doctors it is our role to preserve life:

Death is inevitable

• As doctors we will all at some

point in our careers will be faced

with death

• It is our role to make the best

possible decisions to save lives

• It is our role to make the best

possible decisions when it

comes to withdrawing care

Life's a laugh and death's a joke, it's true.You'll see it's all a show,Keep 'em laughing as you go.Just remember that the last laugh is on you.

Hippocratic Oath:

I will prescribe regimens for the good of my patients according to my ability and my judgment and never do harm to anyone. I will not give a lethal drug to anyone if I am asked, nor will I advise such a plan

Duties of a doctor:

Patients must be able to trust doctors with their lives and health. To justify that trust you must show respect for human life and you must:

Make the care of your patient your first concern


How have we typically justified end of life decisions and is this the right way?

Traditionally decisions to withdraw care have been made on the grounds of futility, from a physiological, probability and economic perspective

PhysiologyBody is no longer responding to drugs or any other form of palliative care. Continued treatment would therefore be futile

ProbabilityConjecture that the patient will not survive even if treatment is administered. Treatment therefore is futile

EconomicContinued care will be too costly with a small chance of success where treatment is continued. Treatment is therefore futile

The concept of futility is nebulous and therefore does not help us, as doctors, to make the most effective, legal and best decisions when it comes to withdrawal of patient care

Airedale NHS Trust v Bland [1993] A.C. 789‘In certain circumstances medical treatment can

properly be categorised as futile, that is, if it cannot cure or palliate the disease from which

the patient is suffering’


Why is best interest now best practice when it comes to end-of-life decision making?

We need to move away from justifying withdrawal of care on the grounds of futility and now make decisions based on what is in the patient’s best interest

• Best interest is now best practice when it comes to end-of-life care decision making

• This form of diagnosis has been supported by recent case law: Bland and re A

• In the context or organ donation, the concept of best interest allow us to consider the following:

Organ donation where the patient is registered on the Organ Donation Register

xxx

Recent Case Law to support Best Interest:

BlandMoreover, a doctor's decision whether invasive care is in the best interests of the patient falls to be assessed by reference to the test laid down in Bolam v. Friern Hospital Management Committee1957] 1 W.L.R. 582 [1993] A.C. 789

In re AIn my judgment best interests encompasses medical, emotional and all other welfare issues[2000] 1 FCR 193, at 200

<Key message to link to next slide to be inserted here?


How can we ensure that we make the right decision when it comes to withdrawal of care?

The GMC Fitness to Practice Panel Hearing provides a strong message that best interest is now a critical factor when making end-of-life care decisions

• In November 2005, the defendant in the GMC Fitness to Practice Panel Hearing was found to have made a decision to withdraw patient care, given Patient S’s condition at the time, that was:

i. clinically unjustified,

ii. inappropriate,

iii.premature,

iv.not in the patient’s best interests

• In 2010...

(Can we add a couple of bullets here about how to ensure making right decision i.e. - Need to properly document decision (perhaps using a policy doc like the LCP? - How can doctors overcome challenges to decisions and be confident they are making the right one)


Summary

1. End of life decisions are an integral part of good medicine

2. There needs to be a clear, patient centred, documented reason

3. This reason may be subject to challenge

Case Studies and Q&A

37


1. Attendees to follow one patient case throughout the case study which is to be split into 2 sections

over a 40 minute period

2. First half of the case study is to focus on patient who is haemodynamically unstable who might be

brainstem dead (15mins)

3. Second half of the case study is to focus on patient who has progressed to a state with a non-

survivable brain injury in the Department of Emergency Medicine (15mins)

4. Group feedback on their discussions is to be included to share views and ideas (10mins)

Agenda for case study break-out session

38


Context:

A motorcyclist trauma case has arrived at the doors of the Emergency Medicine

department. The patient is intubated and ventilated. Upon speaking to the paramedics it

turns out that the patient fell of his bike and hit his head. The patient is rushed to the

neurological department who perform a CAT scan that shows a catastrophic head injury

with suspected lack of brainstem function and that the patient would therefore be unlikely

to respond to any treatment. The patient is taken back to the Emergency Medicine

department where the patient’s family are now waiting for news.

Questions to discuss:

1. What steps do you take as the clinician in charge to proceed with this patient case?

2. What might you use to help you document your patient’s situation to support your

decision making?

3. Who may you need to contact at this point to support you now and later on in the

process?

Case Study Part A

39


Context:

Whilst you are speaking to the family your bleeper goes off informing you that the patient’s

condition has worsened. The patient is no longer breathing for themselves, their pupils are

fixed & dilated and their heart has stopped beating. A nurse has informed you that they

found an ODR card in the patient’s wallet whilst looking for the patient’s identity.

Questions to discuss:

1. What conditions to you suspect and how will you confirm these?

2. What are the options open to you and how will you relate these to the family?

3. What next steps do you need to take once your decision has been made, documented

and agreed by the family?

4. Who may you need to contact at this point to support you and what role would they

play?

Case Study Part B

40

professional development programme for organ donation professor david price dr chris danbury 2...

Documents

deceased organ donation

organ donation agenda

potential organ donation

areas of organ donation

option of organ donation

donation masterclassbest

tissue human tissue

law law