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Product CatalogDental bone and tissue regeneration

hard

& s

oft t

issu

e

soft tissue

education

hard tissue

botissbiomaterials

dental bone & tissue regeneration

2 3

The botiss regeneration system:

Innovation, Safety, Reliability, and Esthetics

botiss biomaterials offers you a unique systematic BTR approach, the complete regenerative bioma-

terial portfolio for Implantology, Oral Surgery, CMF and Periodontology out of one hand.

botissbiomaterials


We all know – no single bone graft or soft tissue

biomaterial is able to suit all medical needs, bio-

logical situations and indications. A variety of fac-

tors (indication, age, hygiene, biotype, bone height,

treatment plan) require a sophisticated approach

with different, coordinated products.

To achieve optimal, predictable results, we offer

you the botiss regeneration system. It includes

all long-term proven biological materials (bovine,

synthetic, allografts, collagen, granules, blocks,

membranes, soft tissue matrices), in various com-

binations for specific indications. The products are

manufactured with the highest quality standards

and all products are strictly biological (e.g. no che-

mical cross-linking).

Patient safety, ease of use, reliable – and predic-

table treatment results – these are your and our

first priorities. The products of botiss regeneration

system have proven their success (safety, efficacy,

reliability) in a multitude of preclinical and clinical

studies, and even more importantly in the daily cli-

nical work with hundreds of thousands of patients

world-wide.

We invest substantially in research and education.

The unique innovations and new clinical solutions

of mucoderm®, maxgraft® bonebuilder and maxre-

sorb® flexbone, the concept of high quality learning

and education with the botiss academy, and our

international bone & tissue days are the results of

our partnerships with world-wide renowned aca-

demic research institutions, global opinion leaders,

and practitioners in their daily clinical environment.

botiss biomaterials, already No. 2 in Europe for

dental BTR with a growing global market share,

provides the botiss regeneration system via a

global network of distribution partners in over 80

countries world-wide. Our distribution partners

and staff are dedicated specialists in dental surgery

and implantology.

botiss is an innovative, clinically oriented Biotech

company headquartered in Berlin, with R&D and

production sites in Germany, Austria and Great

Britain. We are 100% focused on dental regene-

ration.

We proudly welcome you to the botiss regenerati-

on system community. We invite you to share your

experiences and suggestions with us, for improve-

ments or new product concepts.

Dr. Drazen Tadic Oliver Bielenstein

[email protected] [email protected]

cerabone®

Natural bovine bone graft

maxresorb® inject

maxgraft®

boneringmaxgraft®

bonebuilder

Patient matched allogenic bone implant

maxgraft®

Processed allogenicbone graft

Synthetic injectable bone paste

maxresorb®

Synthetic biphasiccalcium phosphate

Processed allogenic bone ring

maxresorb® flexbone*

Flexible block (CaP / Collagen composite)

Straumann® Emdogain®

Enamel matrix derivative

collacone® max*

Cone(CaP / Collagen composite)

mucoderm®

3D-stable soft tissue (Collagen) graft

Jason® membrane

Native pericardium GBR / GTR membrane

collprotect® membrane

Native collagen membrane

Jason® fleece /

collacone®......

Collagenic haemostypt (Sponge / Cone)

* Coming soon

High Quality Learning

Activation

Flexibility

Controlled

DegradationB

iolo

gica

l Pot

entia

l

mucoderm®


Jason® membrane

Jason® fleececollacone®......

hard tissue

cerabone®

Straumann® BoneCeramic™

maxresorb®

inject

maxgraft® boneringmaxgraft® bonebuilder

maxgraft®

EDUCATION

SCIENCE CLINIC

6 - 9 months

6 - 9 months

6 months

4 - 6 months

4 - 6 months

3 - 4months

6 - 9months

3 - 4months

2 - 4weeks

Regeneration

Augmentation

Preservation

Healing

IntegrationIntegration

Barrier

Resorption2 - 3

months

3 - 6 months

bovi

ne

synt

hetic

hum

an

native collagen

collacone®..max*

soft tissue

botiss regeneration system

synthetic + native collagen

botiss academy bone & tissue days

6 - 12months

Regeneration

enamel matrix derivative

Straumann® Emdogain®maxresorb® flexbone*


Synthetic biphasiccalcium phosphate

maxresorb®

4 5

bone regeneration

cerabone®

maxresorb®

maxresorb® inject


cerabone® excellent biofunctionality; superior hydrophilicity and blood uptake.

cerabone® block

cerabone®

Natural Bovine Bone

Grafting Material

Bovine bone grafting material is – due to its reliability and treat-

ment predictability – the material of choice for the majority of

dentists. cerabone® is a highly reliable, dimensionally stable,

safe bone graft. It is derived from the mineral phase of bovine

bone, which shows strong resemblance to human bone (sur-

face, porosity and chemical composition).

Indications:

Implantology, Periodontology, Oral Surgery & CMF

- Sinus lift

- Horizontal augmentation

- Intraosseous defects

- Peri-implant defects

- Extraction sockets

- Vertical augmentation

- Furcation defects

Properties- Natural bovine bone grafting material

- Fast integration by new bone formation

- Long-term 3-dimensional graft stability

- No foreign body or inflammatory reaction

- Rough surface, optimal cell adhesion and

blood absorption

- Interconnective porosity

- Safe and sterile

- Easy handling

Histology of cerabone® 6 months after sinus lift. Optimal integration and bone

healing with cerabone®.

Product Specificationscerabone® granules

Art.-No. Particle Size Content.................................................................... 1510 0.5-1.0mm 1x0.5cc (ml)1511 0.5-1.0mm 1x1.0cc (ml)1512 0.5-1.0mm 1x2.0cc (ml)1515 0.5-1.0mm 1x5.0cc (ml)1520 1.0-2.0mm 1x0.5cc (ml)1521 1.0-2.0mm 1x1.0cc (ml)1522 1.0-2.0mm 1x2.0cc (ml)1525 1.0-2.0mm 1x5.0cc (ml)

cerabone® block

Art.-No. Dimension Content....................................................................1720 20x20x10mm 1xblock

Due to the pronounced hydrophilicity of the cerabone® surface,

mixing with blood or physiological saline solution provides a sui-

table stickiness for optimal moldability. The 3-dimensional porous

network allows fast deposition and penetration of blood serum

and proteins, and serves as a reservoir for proteins and growth

factors.

The unique manufacturing process based on high-temperature

heating removes all proteins and other organic components, and

eliminates potential immunological reactions. cerabone® is the

leading natural bovine bone grafting material of German origin,

as evidenced by clinical and scientific success.SEM: cerabone® macro- and microporesresembling human bone.

SEM: cerabone® microporosity; perfect surface roughness for accelerated cell

attachment.

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Indications:


- Sinus lift

- Ridge augmentation



- Osseous defects

- Furcation defects

Product Specificationsmaxresorb® granulesArt.-No. Particle Size Content........................................................................... 20005 0.5-1.0mm (S) 1x0.5cc (ml)20010 0.5-1.0mm (S) 1x1.0cc (ml)20105 0.8-1.5mm (L) 1x0.5cc (ml)20120 0.8-1.5mm (L) 1x2.0cc (ml)

maxresorb® cylinderArt.-No. Dimension Content........................................................................... 20200 Ø7.5mm; height 15mm 1xcylinder 22201 Ø6.0mm; height 15mm 1xcylinder

maxresorb® blocksArt.-No. Dimension Content........................................................................... 21211 20x10x10mm 1xblock 21221 20x20x10mm 1xblock

Properties- Synthetic, resorbable & safe

- Volume & mechanical graft

stability

- Unique multistep production

process

- 60% HA / 40% β–TCP

- Osteoconductive

- Ultra high interconnected

porosity

- Micropores from ~1-10μm

maxresorb® Synthetic BiphasicCalcium Phosphate

maxresorb® is an innovative, safe, reliable and fully synthetic bone graft subs-

titute with improved controlled resorption properties and outstanding handling

characteristics.

genic cell ingrowth and efficiently promotes the

regeneration of vital bone. The high microporosity

and surface roughness of maxresorb® facilitates

increased diffusion of biological fluids and cell

attachement. maxresorb® is manufactured en-

suring a completely homogenous distribution of

the two calcium phosphate phases; resulting in a

graft material equally reliable to bovine bone. The

unique maxresorb® production process leads to

a highly nano-structured, bioactive rough surface

for improved cell adherence and hydrophilicity.

The homogenous composition of 60% hydroxy-

apatite (HA) and 40% beta-tricalcium phosphate

(β-TCP) results in two active mineral phases: it

supports the formation of new vital bone and

maintains the volume and mechanical stabillity

over a long-time period.

The osteoconductivity of maxresorb® is

achieved by a matrix of interconnecting po-

res ranging from 200-800 μm, and a very

high porosity of approx. 80%. The high ma-

croporosity of maxresorb® is ideal for osteo- ....................................................................

..............................

Histology of maxresorb® 6 months after sinus lift. Optimal integration and bone healing with maxresorb®.

SEM: Structured surface and porosity

SEM: maxresorb® particlePerfect hydrophili-city of maxresorb® granules provides excellent handling characteristics in contact with blood.

maxresorb® inject Innovative Synthetic Injectable Bone Paste

Properties- Injectable & easy handling

- Non-hardening bone graft paste

- Synthetic, resorbable & safe

- Viscous and moldable

- Active hydroxyapatite gel

- 60% HA / 40% β-TCP granules

- Osteoconductive

- Ultra high interconnected porosity

Indications:


- Sinus lift



- Osseous defects

- Furcation defects

water/gelcarrier guidedvascularization

active HAcell activation, bio-active regeneration

bi-phasic Ca/Pbalanced resorption and bone formation volume stability

maxresorb® injectunique injectable synthetic bone graft

Unique Regenerative Four-Phases Activity

maxresorb® inject is a unique and highly innovative, injectable bone

graft paste, with improved resorption properties.

The unique four-phasic homogenous composition of gel, active

hydroxyapatite and granules of 60% HA / 40% beta-TCP sup-

ports the formation of new vital bone, maintains volume and

mechanical graft stability, and is gradually replaced by mature

new bone.

The highly viscous maxresorb® inject paste allows perfect shaping,

molding, fitting and complete bone bonding to the surrounding

bone surface of the defect. maxresorb® inject is a non-hardening

synthetic bone paste.

Product Specificationsmaxresorb® inject

Art.-No. Unit Content....................................................................22005 1x syringe 1x0.5cc (ml)22010 1x syringe 1x1.0cc (ml)22025 1x syringe 1x2.5cc (ml)

maxresorb® inject paste.

Histology of maxresorb® inject 6 months after sinus lift. Optimal integration and bone healing with maxresorb® inject.

maxresorb® inject perfect blood adherence.

SEM: maxresorb® inject surface structure.

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maxresorb® inject - easy handling and good moldability.

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Straumann® BoneCeramic™Synthetic Biphasic Calcium Phosphate

Properties- osteoconductive

- biocompatible

- 100 % synthetic

- safe, reliable, sterile

- slowly resorbable

- extensively clinically documen-

ted in approx. 25 clinical- and

20 pre-clinical studies

(pubmed research)

Straumann® BoneCeramic™ is a fully synthetic bone graft substitute

of medical-grade purity in particulate form. It is designed to support

bone regeneration and preservation of bone volume.

BoneCeramic™ is composed of biphasic calcium phosphate – a

mixture of 60 % hydroxylapatite (HA), which is 100 % crystalline,

and of 40 % of beta tricalciumphosphate (β-TCP).

Hydroxylapatite (HA) undergoes very slow resorption, therefore

helps to maintain a scaffold over time, which is necessary for volu-

me preservation. β-TCP undergoes faster degradation allowing for

substitution by the patient’s own bone.

Combining the features of these two materials, BoneCeramic™

gradually resorbs and is substituted by the patient’s own vital

bone, without compromising the bone volume preservation.

The manufacturing process features homogeneous phase

distribution and batch-to-batch consistency. BoneCeramic™ is

90 % porous and has interconnected pores of 100–500 microns

in diameter, facilitating the ingrowth of bone forming cells and

nutritive blood vessels.

Indications:


- bony defects of the alveolar

ridge

- tooth extraction sites

- sinus floor elevation

- intrabony periodontal

osseous defects and furcation

Product SpecificationsArt.-No. Particle Size Content....................................................................070.203 0.4-0.7mm 1x0.25g 070.204 0.5-1.0mm 1x0.5g 070.205 0.5-1.0mm 1x1.0g

Hystology of BoneCeramic™ providing a strong matrix for bone regeneration in a mini pig model 32 weeks after implantation

Highly porous structure of BoneCeramic™ facilitating ingrowth of bone forming cells

and nutritive blood vessels

Handling made easyWhen applied, BoneCeramic™ rapidly absorbs

fluids, forming granular putty. The wetted granules

adhere to the application instrument and subse-

quently fit the bony defect nicely.

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tissue regeneration

Jason® membrane


collacone®


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Jason® membrane Pericardium GBR/GTR Membrane

Properties- Long-lasting barrier function

for ~ 12-28 weeks

- Native structure of low thickness

- Easy manipulation, can be

applied dry or wet

- No stickiness after rehydration

- Fast vascularization due to

3-dimensional structure

- Multidirectional strength and

tear resistance

Indications:

Implantology, Periodontology, Oral Surgery & CMF- Implant dehiscence

- Sinus lift

- Protection of Schneiderian

membrane

- Fenestration defects


- Ridge preservation

- Horizontal & vertical

augmentation

- Alveolar ridge reconstruction


(1-3 walls)

- Furcation defects (class I-II)

Product SpecificationsJason® membraneArt.-No Size Content....................................................................681520 15x20mm 1 membrane 682030 20x30mm 1 membrane 683040 30x40mm 1 membrane

SEM: Jason® membrane.

SEM: Jason®

membrane 3-dimensional structure.

Good handling of Jason® membrane after rehydration.

Histology of Jason® membrane 24 weeks after implantation shows perfect integration without inflammatory reaction.

Jason® membrane provides a long-lasting, adequate barrier

function for ~12-28 weeks.

Due to the unique, patented production process, the superior pro-

perties of the native pericardium are preserved, maintaining the

characteristics of its natural tissue. The use of Jason® membrane

for regeneration of bone and tissue is an essential component of the

GBR and GTR concept.

collprotect® membrane Natural Collagen Membrane

Properties- Three dimensional natural collagen matrix

- Controlled wound healing and blood clot

support

- Optimal barrier function in GBR/GTR

procedures

- Resorption time approx. 8-12 weeks

- Easy application and handling in dry or wet

status

- Rough and porous structure for cell guidance

- Natural collagen structure

Indications:

Implantology, Periodontology, Oral Surgery & CMF- Protection or covering of

minor perforations of the

Schneiderian membrane

- Sinus lift

- Socket preservation

- Horizontal and/or vertical

ridge augmentation

- GBR/GTR simultaneous use

with bone substitutes

- Fenestration and dehiscence

defects

Product Specifications collprotect® membraneArt.-No Size Content....................................................................601520 15x20mm 1 membrane602030 20x30mm 1 membrane603040 30x40mm 1 membrane

Histology 6 weeks after implantation ofcollprotect® membrane: blood vessels havepenetrated the porous structure.Collagen fibres are visible and the resorptionproceeds without any inflammatory tissueresponse.

collprotect® membrane is a natural collagen membrane. Due to the rough and porous

three dimensional collagen structure, controlled wound healing in combination with

guided bone and tissue regeneration achieves optimal treatment results. During the

regeneration process the collprotect® membrane offers the necessary barrier function

balanced with a controlled resorption time without inflammatory soft tissue reaction.

The soft tissue around the collprotect® membrane usually heals without complica-

tions, also in cases of postoperative dehiscence. The pore size of the collprotect®

membrane prevents rapid ingrowth of soft tissue whilst still allowing blood vessel

and nutrient penetration leading to quick integration into the surrounding tissue. This

unique biological function provides a perfect basis for hard and soft tissue healing.

.................................................

SEM: collprotect® membrane SEM: collprotect® membrane

12 13

Product Specifications

collacone® Art.-No Shape Dimension Content ....................................................................................................................511112 ~16mm height, 12 pieces width on top ~ 11mm, (single sterile bottom width ~7mm units)

collacone® Native Collagen Cone

Indications:

Implantology, Periodontology & CMF

- Closure of extraction sites

- Biopsy sites

- Minor oral wounds

- Control and stop of bleeding

in extraction sockets or

biopsy sites

- Internal sinus liftProperties- Resorption within ~2-4 weeks

- Stabilization of blood clot and efficient local

haemostasis

- Maintains integrity in the presence of blood

and during application

- Wound protection

- Three dimensional matrix for tissue ingrowth

- Controlled wound healing process

- Native collagen cone

- Haemostatic reactivity

collacone® is both a resorbable native collagen cone intended to

assist the wound healing process, and a natural matrix providing

the structure for new bone formation.

The healing of an extraction socket following tooth removal is cha-

racterized by the formation and maturation of a blood clot, follo-

wed by infiltration of fibroblasts to replace the coagulum, and finally

establishment of a provisional matrix that allows new bone tissue

formation in the extraction socket.1

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collacone® wet-stable, fast uptake of blood and stabilization of the blood coagulum.

SEM: collacone® collagen fibres 3-dimensional network.

1 G. Cardaropoli et al. J Clin Periodontol 2003; 30: 809-818

SEM: collacone®

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Clinical use of collacone®.

Product comparison

Jason® membrane


versus

Origin Pericardium Dermis

Degradation 12- 28 weeks 8- 12 weeks

Structure Differently oriented collagen Dense network of collagen

fibers providing multi-directional bundles with pores for better

tear resistance vascularization

Handling Highly adaptive Slightly rigid

Product Specifications

Jason® membrane Art.-No. Size Content

....................................................................

681520 15x20mm 1 Membrane



collprotect® membrane Art.-No. Size Content

....................................................................




Barrier function

Degradation

Vascularization

Keyfactors for barrier membranes

14 15


Enamel Matrix Derivative, 30 mg/mL

Properties- Induces true regeneration as evidenced by human histological studies

- Easy to apply in difficult accessible defects and in minimal invasive procedures

- Shows less complications compared to membranes

- Well researched with 800 scientific and 200 clinical publications

- Based on 10-year long-term evidence in intrabony and recession defects

- May be combined with various bone graft materials

- Available in 3 different volume sizes allowing flexible treatment options

- Stimulates bone formation and angiogenesis

Indications:

- GTR, intrabony and wide

intrabony defects

- Recessions

- Class I and II furcation defects

- Extraction sites

Literature

Sculean et al, Clin Adv Periodontics 2011; 1:101-117 // Grandin et al. Tissue Eng Part B Rev. 2012 Jun;18(3):181-202. // Bosshardt et al, Periodontology 2000,2009, 51:208-2019.

Product Specifications Straumann® Emdogain®

Art.-No Product Content...............................................................................................................................................075.098 Straumann® Emdogain® 0.15 mL 5 x 0.15 ml Emdogain®

075.101 Straumann® Emdogain® 0.3 mL 1 x 0.3 ml Emdogain®

075.102 Straumann® Emdogain® 0.7 mL 1 x 0.7 ml Emdogain®

075.114 Straumann® Emdogain® 0.3 mL multipack 3 x 0.3 ml Emdogain® 3 x 0.6 ml PrefGel®075.116 Straumann® Emdogain® 0.7 mL multipack 3 x 0.7 ml Emdogain®

3 x 0.6 ml PrefGel®075.117 Straumann® Emdogain® PLUS 1 x 0.7 ml Emdogain® 1 x 0.6 ml PrefGel® 1 x 0.25 g BoneCeramic™ (400-700 mm)075.203 Straumann®PrefGel® 5 x 0.6 ml PrefGel®

Straumann® Emdogain® is a well-researched easy-to-apply gel con-

taining Enamel Matrix Derivative originating from unerupted porcine

tooth buds. As a component of embryonic tissues it is designed to

promote predictable regeneration of hard and soft tissues lost due

to periodontal disease or trauma.

The main component in Emdogain® is amelogenin, which under phy-

siological conditions assembles into an insoluble matrix. This matrix

has proved the ability to stimulate various cell types involved in the

wound healing cascade of soft and hard tissues (mesenchymal stem

cells, osteoblasts, fibroblasts, periodontal ligament cells and cemen-

toblasts) towards a regenerative pattern.1-wall intrabony defect before and 8 years after periodontal regeneration with Emdogain®

(Dr. G. Heden, Karlstad, Sweden)

Histological micro-graph of periodontal ligament (Priv. Doz. Dr. D. Bosshardt, Uni Bern)

Caprilary sprouting from aortic arch explantswithout (left) and with Emdogain® (right)

(Prof. M. Ågren, Copenhagen, Denmark)

Intraosseous defect before and 2 years after treatment with Emdogain®

(Dr. J. Doobrow, Cullman-Al, USA)

The product can be ideally combined to enhance the

biological performance of bone graft materials, like

maxgraft®, maxresorb®, Straumann®BoneCeramic™

and cerabone® and collagen products like the muco-

derm or Jason® membrane

Clinical situation after extraction

After tooth extraction, a

large-volume socket is visible

Insertion of collacone® in the

extraction socket

cerabone® 0.5-1.0mm particle

size is inserted

Suturing and open healing

Covering with a soft tissue

punch and suturing

Clinical situation after healing

and implantation

Clinical situation after four

weeks healing time

Clinical Cases Implantology, Periodontology, Oral Surgery & CMF

Extraction socket: collacone®

Dr. Fernando Rojas-Vizcaya, Castellón & Chapel Hill

Socket preservation: cerabone®

PD Dr. Adrian Kasaj, Mainz

After surgical extraction a large

bone defect is visible

Filling of the defect with

maxresorb® inject

Bone grafting material in place Wound closure

Ridge preservation: maxresorb® injectDr. Minas Leventis, Athens

Clinical situation after extraction mucoderm® placed vestibu-

larly and filling of socket with

maxgraft®

Bony regeneration at time of

re-entry

Final prosthetic restoration

Socket preservation: maxgraft®; mucoderm®

Dr. Algirdas Puisys, Vilnius

16 17


Sinus lift: cerabone®; Jason® membraneDr. Alessandro Rossi, Milan

Clinical view of the sinus lift area

Preparation of a lateral sinus

window

Preparation of the lateral sinus

lift window

Sinus lift and additional lateral

augmentation with maxre-

sorb® 0.8-1.5mm

Filling of the sinus cavity with

cerabone® 1.0-2.0mm particle

size

Covering of the augmentation

area with Jason® membrane

Covering the lateral sinus lift

area with Jason® membrane

20x30mm size

Bony regeneration six months

after implant insertion

Sinus lift & lateral augmentation: maxresorb®; Jason® membranePD Dr. Dr. Daniel Rothamel, Cologne

Filling of sinus cavity with

cerabone® 1-2mm

Immediate implantation Clinical view after augmentation

with cerabone® and implant

insertion

Final prosthetic restoration

Sinus lift and ridge augmentation with simultaneous implantation: cerabone®; Jason® membraneDr. Derk Siebers, Berlin

Filling of subantral cavity with

cerabone® 1.0-2.0 mm


site with collprotect® membrane

Soft tissue defect coverage

with Jason® fleece and wound

closure

Soft tissue situation after six

months healing time

Sinus lift: cerabone®; collprotect® membrane; Jason® fleeceDr. Viktor Kalenchuk, Chernivtsi


Ridge augmentation: maxgraft® bonebuilder; Jason® membrane Dr. Markus Schlee, Forchheim

Clinical situation before

maxgraft® bonebuilder

augmentation

Clinical situation after implant

placement

maxgraft® bonebuilder block

fixation, perfect bone to block

surface contact

Vertical and horizontal augmentati-

on with cerabone® and maxgraft®

particles (mix ratio 1:1)

Complete maxgraft® bonebuil-

der block coverage with Jason®

membrane 20x30mm size


area with Jason® fleece soaked

with PRF®

Wound closure and suturing

Covering with patient‘s own

PRF® matrix

Ridge augmentation: cerabone®; maxgraft®; Jason® fleece; PRF® Dr. Reda Benkiran, Cannes

Situation before implantation

and augmentation

Implantation and augmenta-

tion with maxresorb® inject


site with Jason® membrane

Situation four months post-OP

after healing

Ridge augmentation with simultaneous implantation: maxresorb® inject; Jason® membraneDr. Dr. Andres Stricker, Konstanz

Clinical situation Jason® fleece placed in biopsy

harvesting site

Closure of biopsy site Recession coverage with gingival

soft tissue graft

Filling of biopsy harvesting site: Jason® fleeceDr. Roland Török, Nuremberg

18 19

Product Portfolio Product Codes

Jason® membraneArt.-No Size Content....................................................................681520 15x20mm 1 membrane 682030 20x30mm 1 membrane 683040 30x40mm 1 membrane

collprotect® membraneArt.-No Size Content....................................................................601520 15x20mm 1 membrane602030 20x30mm 1 membrane603040 30x40mm 1 membrane

collacone® Art.-No Shape Dimension Content ....................................................................................................................511112 ~16mm height, 12 pieces width on top ~ 11mm, (single sterile bottom width ~7mm units)

Hard tissue regeneration

Soft tissue regeneration

cerabone® granulesArt.-No. Particle Size Content....................................................................

1510 0.5-1.0mm 1x0.5cc (ml)1511 0.5-1.0mm 1x1.0cc (ml)1512 0.5-1.0mm 1x2.0cc (ml)1515 0.5-1.0mm 1x5.0cc (ml)1520 1.0-2.0mm 1x0.5cc (ml)1521 1.0-2.0mm 1x1.0cc (ml)1522 1.0-2.0mm 1x2.0cc (ml)1525 1.0-2.0mm 1x5.0cc (ml)

cerabone® blockArt.-No. Dimension Content....................................................................1720 20x20x10mm 1xblock

maxresorb® granulesArt.-No. Particle Size Content.................................................................... 20005 0.5-1.0mm (S) 1x0.5cc (ml)20010 0.5-1.0mm (S) 1x1.0cc (ml)20105 0.8-1.5mm (L) 1x0.5cc (ml)20120 0.8-1.5mm (L) 1x2.0cc (ml)

maxresorb® cylinderArt.-No. Dimension Content.................................................................... 20200 Ø7.5mm; height 15mm 1xcylinder 22201 Ø6.0mm; height 15mm 1xcylinder

maxresorb® blocksArt.-No. Dimension Content.................................................................... 21211 20x10x10mm 1xblock 21221 20x20x10mm 1xblock

maxresorb® injectArt.-No. Unit Content....................................................................22005 1x syringe 1x0.5cc (ml)22010 1x syringe 1x1.0cc (ml)22025 1x syringe 1x2.5cc (ml)


Art.-No Product Content...............................................................................................................................................075.098 Straumann® Emdogain® 0.15 ml 5 x 0.15 ml Emdogain®

075.101 Straumann® Emdogain® 0.3 ml 1 x 0.3 ml Emdogain®

075.102 Straumann® Emdogain® 0.7 ml 1 x 0.7 ml Emdogain®

075.114 Straumann® Emdogain® 0.3 ml multipack 3 x 0.3 ml Emdogain® 3 x 0.6 ml PrefGel®075.116 Straumann® Emdogain® 0.7 ml multipack 3 x 0.7 ml Emdogain®

3 x 0.6 ml PrefGel®075.117 Straumann® Emdogain® PLUS 1 x 0.7 ml Emdogain® 1 x 0.6 ml PrefGel® 1 x 0.25 g BoneCeramic™ (400-700 mm)075.203 Straumann® PrefGel® 5 x 0.6 ml PrefGel®

Straumann® BoneCeramic™Art.-No. Particle Size Content....................................................................070.203 0.4-0.7mm 1x0.25g 070.204 0.5-1.0mm 1x0.5g 070.205 0.5-1.0mm 1x1.0g

..................................................

More than a partnership. A synergy of strengths.

Today, almost every second implant treatment requires GBR proce-dures. We as a global leader in implant and restorative dentistry are driving this trend by partnering with botiss, a leading manufacturer of high-quality dental biomaterials.

ѹ Dental biomaterials for every indication and preference to complement implant therapy

ѹ Implants, biomaterials and prosthetics out of one hand

Learn more about our products at www.straumann.com/regen

Ad_Botiss_A4.indd 1 25.07.14 15:44

20Rev.: PKSsw-01/2014-09

soft tissue

education

hard tissue

botiss dental GmbH

Uhlandstraße 20-25

10623 Berlin / Germany

Fon +49 30 20 60 73 98 30

Fax +49 30 20 60 73 98 20

[email protected]

www.botiss.com

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