Providing 10 hardy strains of probiotics with a strong potency of 10 Billion CFUs

60 grams per bottle (serving size 1 gram or ¼ teaspoon)

Suggested use:

as a dietary supplement take ¼ teaspoon (approximately 1 gram, supplying 10 billion CFUs) daily mixed with formula, juice, water, apple sauce or other solid foods at room temperature (never a hot beverage) or as directed by a healthcare practitioner. A nursing mother may want to dip her finger into the powder and pat the baby’s lips before nursing.

ProDermix® Powder for Infants is intended for daily use to provide a wide spectrum of support for healthy maintenance of gastrointestinal and immune system function in infants up to the age of 3 years.

Suggested for Infants from birth to three years of age:

ProDermix® Powder for Infants is a high potency probiotic supplement created to safely meet the needs of infants up to the age of 3 years.

Probiotic supplements contain live, “friendly” bacteria that promote proper digestion, support immune system function, aid in absorption of vitamins, and defend against potentially harmful bacteria.

Healthy bacteria colonize the gastrointestinal tract from birth and are critical for the development of an infant’s intestinal and immune system. However, this process can be disturbed by Caesarean section, formula feeding, infections and antibiotics, potentially leading to a weakened immune system with allergic symptoms and susceptibility to disease. ProDermix® Powder for Infants contains probiotics that help restore microflora balance and support healthy gastrointestinal and immune system function in infants.

Immune system support:

ProDermix® Powder for Infants supplies five Lactobacillus strains necessary for healthy development of the infant immune system. In clinical tests they have shown their ability to reduce the risk of atopic eczema and other food allergies. Five Bifidobacterium strains predominant in an infant’s gastrointestinal tract are also included to help regulate immune response to allergens.

Antibiotic therapy: Antibiotics suppress infections caused by invading adverse bacterial microorganisms.

Simultaneously, they also destroy multitudes of healthy flora (microorganisms) which the immune system needs to fight pathogens and fungus. Recurring ear and throat infections are usually the results of strong antibiotics. ProDermix® Powder for Infants helps restore and revitalize the healthy flora required to defeat the recurrence of invading pathogens in the intestinal tract.

ProDermix® Powder for Infants APD 12

Support for an infant’s metabolism:

An infant’s gastrointestinal tract is not fully mature and cannot properly digest some parts of the lactic acid produced by certain Lactobacillus species often found in adult probiotics, such as L. acidophilus and L. reuteri. ProDermix® Powder for Infants contains healthy microbiata that are agreeable and safe for an infant’s gastrointestinal tract and metabolism.

Diarrhea relief for infants:

The probiotic strains in ProDermix® Powder for Infants antagonize microbes in the intestines such as E. coli, Clostridium perfringens (food poisoning), and C. difficile usually the cause for rotavirus diarrhea and other infections in infants.

*Additional Symptoms addressed by the Infant Powder Formula:

(some of the following symptoms may also find relief from the formula) Colic baby, colitis, diarrhea, cradle cap, diaper rash, eczema, IBS, thrush, digestive disorders, immune system support etc.

Probiotics and Prebiotics: ProDermix® Powder for Infants contains prebiotics that help the proliferation

and strengthening of the healthy flora.

ProDermix® Powder for Infants powder formula of 10 billion CFU’s contains L. rhamnosus and L. casei among other significant beneficial probiotic strains plus prebiotics supporting increased health benefits of infants in their early stages of life.

Several of the strains in the Infant Powder formula are not in our previous formulas: they include L. gasseri, L. salivarius, B. breve, and B. infantis, which have demonstrated favorable relief for colitis, IBD, colonic diseases and allergies.

Hypoallergenic ingredients:

Probiotics used in ProDermix® Powder for Infants are cultured on vegetable-based growth media. It is free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, corn, yeast, and soybeans. Contains no artificial colors, flavors, or preservatives. Inulin, a dietary fiber derived from chicory root, is used as a base ingredient. ProDermix® Powder for Infants contains only pure potent probiotics. ProDermix® formulas do not contain any artificial additives or fillers and are NON GMO.

Potency Guarantee:the potency of our ProDermix® formula stated on the bottle is guaranteed until the

expiration date, which is usually one year from manufacture. Stability tests, are subject to being spot checked by the FDA to verify the data. (Some brands show an asterisk by the potency and in small print on bottom of the bottle it says ‘at time of manufacture’ which usually means that the potency does not last very long.)

NOTE: Powder formulas are usually manufactured with higher amounts of potency of CFU’s than capsules. Original potency may be compromised during the swallowing process and or the mixing with food or beverages. Expert healthcare practitioners and doctors in the field of probiotics have stated that the stronger potency is safe and palatable for infants even at their delicate age.

CAUTION: The spoon used to measure the formula must always be dry. A damp or wet spoon can reduce the potency of the formula and render it useless. Dampness and wetness are more detrimental to probiotics than heat.

*Symptom Disclaimer: The symptoms mentioned are culled from research done in clinical tests on certain probiotic strains similar to the ones found in our formula. However, the specific strains in our formulas were not individually tested as to their performance.

General Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Effective Highlights of the 10 Probiotic Strains inProDermix® Powder Formulaof Probiotics

for Baby & Mom

Full description of Probiotic Strains: Lactobacillus casei:L. casei helps create an intestinal environment favorable to the growth of other probiotic

organisms while antagonizing pathogens such as E. coli and Staphylococcus aureus. Studies indicate L. casei helps improve conditions of constipation in infants and children. It has also shown to suppress allergic responses in preschool children. A double-blind, controlled clinical trial involving 231 preterm infants found supplementing of L. casei along with B. breve for the first month of life significantly reduces the risk of developing severe enterocolitis.

Lactobacillus gasseri:L. gasseri exhibits good mucosal adherence, bile-tolerance, and is one of the few known

bacteria capable of enzymatically binding and sustaining fructose into the beneficial prebiotic, inulin. L. gasseri produces a number of antimicrobial substances including hydrogen peroxide. L. gasseri produces gassericin which is a killer bacteria that kills E. coli and other harmful bacteria (reported in Nature Reviews Microbiology). A double-blind, placebo-controlled clinical study found supplementation with a probiotic blend containing L. gasseri, B. longum, and B. bifidum significantly reduced the duration and symptom severity of common cold infections.

Lactobacillus paracasei:L. paracasei is an acid-tolerant organism that survives passage through the intestinal

tract and promotes the growth of other lactobacilli. L. paracasei is antagonistic to Candida albicans among other pathogens. Clinical studies have documented supportive benefits of L. paracasei in conditions ranging from non-rotaviral diarrhea to allergic disorders. A prospective study examining fecal specimens of over 500 infants found colonization of the intestinal tract with L. paracasei significantly reduces the risk of atopic dermatitis.

Lactobacillus rhamnosus:This Lactobacillus is perhaps the most clinically studied of all probiotic organisms. L

rhamnosus has very good adherence characteristics to the mucosal lining and exhibits extraordinary defiance towards microbial pathogens. The following pathogens were studied as being antagonized successfully by L. rhamnosus: E. coli, C. difficile C. albicans, Klebsiella pneumonia, S. aureus and Shigella among others. In clinical trials, L. rhamnosus has proven

highly effective at reducing the risk and severity of infant diarrhea. Trials have also shown that L. rhamnosus administered prenatally to expectant mothers and postnatal to their infants significantly lowers the risk of developing eczema during childhood.

Lactobacillus salivarius:L. salivarius is a resident of the intestinal tract with good survival and adherence

characteristics. Preclinical research indicates L. salivarius favorably modulates inflammatory and allergic reactions. In studies involving mice with allergy induced asthma, L. salivarius significantly lessened the obstructiveness of the airway passages.

Bifidobacterium bifidum:B. bifidum produces enzymes that help degrade dietary proteins and digestion-resistant

carbohydrates such as lactose. It has a normalizing effect on colonic performance and has been shown to rapidly reduce stool frequency in infants with both rotaviral and non-rotaviral diarrhea. Studies suggest B. bifidum has important immunoregulatory effects. A controlled clinical trial involving expectant mothers with a family history of allergic disorders found administration of a formula containing B. bifidum, B. lactis, and Lactobacillus acidophilus significantly reduced the incidence of eczema in their infant offspring during the first 12 months of life.

Bifidobacterium breve:B. breve is the predominant species of Bifidobacteruim found in fecal samples of

breastfed infants. Compared to other bifidobacteria, B. breve exhibits superior survival capacity in the presence of antibiotics. It also produces substantial quantities of lactase and may help mitigate symptoms of lactose intolerance. Studies also indicate B. breve may be useful as increasing antibody responses to influenza, polio, and possibly other viral organisms. A double-blind, placebo-controlled trial found administration of B. breve along with prebiotics significantly reduced wheezing and other respiratory symptoms in atopic infants at high risk of developing asthma.

Bifidobaterium infantis:As its name implies, B. infantis is naturally found in the intestinal tracts of infants. B.

infantis is highly antagonistic to intestinal pathogens. It also has a strong suppressive effect on Bacteroides vulgatus, a bacteria thought to play an important role in the development of inflammatory bowel disease (IBD).

Bifidobacterium lactis:This hardy organism is acid-resistant and displays and exceptionally high adhesive

capacity to human intestinal mucus. Like L. paracasei, B. lactis secretes peptidase enzymes that help facilitate the digestion of dietary allergens like casein. Added to infant formulas, B. Lactis has been shown to reduce the incidence of diarrhea in residential can childcare settings and to improve weight gain in preterm, antibiotic-treated infants. In a randomized, double-blind study, administration of B. lactis to infants with atopic eczema for two months led to significant improvements in skin condition. Trials utilizing B. lactis together with B. bifidum and other probiotic organisms have likewise reported significant reductions in the incidence of eczema among high-risk infants.

Bifidobacterium longum:B. longum is among the first colonizers of the newborn intestinal tract and, like B. breve

and B. infantis, predominates in the microflora of healthy, breastfed infants. B. longum supplementation significantly reduces diarrhea and abdominal pain for persons taking antibiotics.

SPECIAL REPORTBenefits of Probiotics & Prebiotics during Pregnancy,

Nursing and Child Infancy

PregnancyIn the American Journal of Clinical Nutrition (Intake of probiotic food etc. [2011])

it is reported that pregnant women who consume approximately three ounces per day of probiotic-containing yogurt have a significantly reduced risk of spontaneous preterm delivery. While preliminary, these data suggest oral probiotic administration during pregnancy is not only safe, but may represent a therapeutic strategy to prevent preterm labor and delivery.

Swallowing capsules of probiotics with food deliver way more CFU potency than yogurt can offer.

Reducing glucose intolerance during and after pregnancy (gestational diabetes)

A study was conducted in the Aga Khan University in Karachi, Pakistan in September 2011 to assess the effectiveness of Lactobacillus rhamnosus in reducing glucose intolerance during and after pregnancy. Women with Gestational Diabetes Mellitus (GDM) are many times more at risk of developing type 2 diabetes compared with those who had a normal pregnancy. Untreated GDM is associated with higher incidence of complications during pregnancy and increases the risk of infant defects and death.

Probiotics, the live micro-organisms, have shown promising results in regulating glucose metabolism among pregnant mice. The effect of probiotics on glucose metabolism is attributable to their immunoregulatory properties. They elicit powerful anti-inflammatory capabilities which compromise harmful microbial activity in the immune system. The safety of L. rhamnosus among pregnant women is already well established in other diseases.

A 2008 clinical trial reported in the British Journal of Nutrition found initiating probiotic supplementation and dietary counseling during the first trimester of pregnancy results in significantly better maternal blood glucose control than does dietary counseling alone. A clinical trial from the Journal of Pediatrics (2008) reported use of probiotics during pregnancy, coupled with administration of both probiotics and prebiotics to infants significantly reduces the incidence of respiratory infections during the first two years of life. In 2001, a landmark clinical trial (reported in Lancet magazine) examined the effects of administering the probiotic L. rhamnosus prenatally to pregnant women with a family history of atopic eczema and postnatal allergies to their infants. After two years, researchers found the incidence of atopic eczema in children who had received probiotics was half that of children who had received a placebo. Follow-ups to this study revealed a remarkable persistence with the same successful results due to the probiotic effect.

NursingProbiotic intake during lactation (nursing) may enhance mammary gland production and

secretion of immunoprotective agents such as immunoglobulin A (IgA), thereby producing a higher degree of immune response to nursing infants. Rotavirus induced diarrhea may also compromised in those infants. In 1997, a trial in Finland examined the effects of administering 40 billion CFU/per-day of L. rhamnosus to nursing mothers of infants with atopic eczema. After one month, researchers noted a significant decline in inflammatory symptoms in infants whose mothers had received the particular probiotics. The British Journal of Nutrition (2008) documented significant reductions in gastrointestinal disturbance in healthy, breastfeeding infants following administration of Lactobacillus casei to nursing mothers.

Child InfancyProbiotics are highly beneficial for infants in their early stages of life (birth to two years

of age). Probiotics with potency higher than fifty billion CFU's have been administered to infants below three months of age successfully with no adverse reactions.

Probiotics with prebiotics administered directly to infants, including infants classified as low birth weight (LBW) produce a myriad of healthy benefits for the infant. Probiotics promote colonization of the infant gut with beneficial organisms, inhibit the activity of pathogens, improve the function of the intestinal mucosal barrier, and help regulate immune responses. A recent study found that supplementing LBW infants with probiotics significantly reduces feeding intolerance and enhances weight gain. If the infant is nursing satisfactorily, it is highly beneficial when the nursing mother consumes the probiotics which are then transferred to the child.

An infant from birth until age two does not have enough maturity in the intestinal tract with sufficient healthy microflora. Insufficient microflora in the intestines may cause weak development of the child’s digestive system and immune system. The child may be susceptible to many allergies and diseases.

Dysbiosis (“biosis’ in greek means ‘way of life’ usually used in biological terms, Symbiosis means agreeable way of life of species of bacteria – Dysbiosis means disagreeable way of life) of the intestinal flora may lead to gastrointestinal disorders linked to Inflammatory bowel disease, irritable bowel syndrome, allergies, yeast infections (candida) ENT complications, diabetes, and various allergies, and some behavioral disorders such as autism. Probiotics restore and rejuvenate the microflora of the intestinal tract and digestive system, optimizing the child’s health and boosting the immune system.

ProDermix® has recently manufactured an infant’s powder formula of 10 billion CFU’s containing L. rhamnosus and L. casei among other significant beneficial probiotic strains plus prebiotics for the health benefits of infants in their early stages of life.

Several of the strains in the Infant Powder formula are not in our previous formulas: they include L. gasseri, L. salivarius, B. breve, and B. infantis, which have demonstrated favorable relief for colitis, IBD, colonic diseases and allergies.

*Symptom Disclaimer: The symptoms mentioned are culled from research done in clinical tests on certain probiotic strains similar to the ones found in our formula. However, the specific strains in our formulas were not individually tested as to their performance.

**General Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This exclusive report was compiled by the Prodermix® Institute of Probiotics

Research and Discovery affiliate of American Nutrition Consultants

Usher Brecher, President of our company delivers seminars regarding the benefits and effectiveness of ProDermix® Probiotics

call or email for an appointment in your community or health food store.