!"#$%&$'()*+#$

!"#$%&'()"*+,+,-(!*"'(.(

Who Are We?

A fully credentialed manufacturer of high performance skin care products and health benefiting supplements

We offer a stock line of low minimum products (6 units per product)

Our products are labeled and branded using our clients name

We use medical grade, high potency ingredients formulated at very high concentrations

What We Do?

We provide innovative high end skin care products and nutritional supplements to:Skin Care

Physicians-Plastic Surgeons, Dermatologists Naturopaths High-End Spas Destination and Resort SpasMedi-Spas

SupplementsPhysiciansNaturopathsChiropractorsSports StoresGymsSupplement Stores

What We Do?Provide a science based approach to formulation using experienced chemists and physicians

We search world wide to source the most powerful and effective ingredients. France, Switzerland, Germany, Italy, Australia and many more

We use breakthrough innovative ingredients that are considered best in their class

We provide the most powerful ingredients available, and they are formulated in higher than expected concentrations

We offer a convergence of science, advanced engineering, and highly responsive ingredients

95-99% Of Our Ingredients Are Actives

Anti-Agingwrinkle reduction

visualbeauty

and elastin

oxidative stress

What We Do?Our products benefit all age groups and skin types but our focus is:

What We Do? The Skin Care Company?

We stimulate the skin for rapid and dramatic improvements in its appearanceDramatically improve the appearance of:

fine lines and wrinklesreduce the appearance of age spotsdiscolorationsimprove skin elasticity and collagen productionimprove texture reduce puffiness improve skin hydration and tone

What We Do?

Our anti-aging products are designed to produce extraordinary resultsDesigned to be at the head of the most impressive class of skin care productsNothing currently on the market comes close to matching their effectiveness

that are formulated at very high concentrationsspecifically designed to work synergisticallydesigned to be highly bio-available and penetrate deeply

What We Do?Scientific team of chemists, physicians, para-medical aestheticians and other healthcare professionals

State of the art ingredient technology

High levels of bio-actives

Molecular engineering

Process engineering

Credentialed Manufacturing

State of the Art manufacturing facility with an:In-house analytical & formulation laboratorySeparate enclosed production clean roomsAmbient clean air systemWater purification and monitoring systemsVendor certification programIngredient authentication Global sourcingcGMP CertifiedNSF CertifiedFDA Audited

Owned By Healthcare Professionals

Dr. Angela DeRosa DO, MPH, CPE,(Chief Medical and Compliance Officer), board certified Internist specialized in

two AZ medical schools, past senior medical director for P&G Pharmaceuticals.

Mirijana Potocnjak, (Chief Scientist and Operations Officer) is a biologist/chemist with 13 years of nutraceutical and skin care product development experience. Extensive background in herbs, botanicals, and organic ingredients. She is the primary formulating chemist for our products.

Judy Curran RN, (Chief Executive and Marketing Officer)educated both as a Registered Nurse and in Business, has over 30 years experience in domestic and international business and product development within the health and beauty industry. Clinical experience in Burns, Wound Care, and Skin Care.

Stock Product Line

SKIN CARE PRODUCTS

PEPTIDE ANTI-AGING SERUM -1oz STEM CELL SERUM ! ozTIGHTENING SERUM 1 ozPEPTIDE EYE SERUM - ! ozEYE LASH LENGTHENER LIGHTENING SERUM 1 ozCELLULITE CREAM 5 ozFACIAL/BODY HAIR INHIBITOR 1 oz

SUPPLEMENT PRODUCTS

THERMOGENIC APPETITE SUPPRESSANTWEIGHT LOSS CARBOHYDRATE CONTROLWEIGHT LOSS FAT BURNER (LIPOTROPIC) NATURAL HAPPINESSLIVER SUPPORT MENOPAUSE SYMPTOM RELIEF JOINT SUPPORT MUSCLE CRAMP OIL Q IMMUNE

Biology, Peptides And Serums

Understanding The Basics Of Our Formulas

Cosmetic serums are highly concentrated skin treatment products

Ingredients in serums are generally 10 times more concentrated and biologically active than in creams

Serums use powerful targeted ingredients of small molecular sizes in order to penetrate deeper and more quickly than creams

Serums are considered the primary vehicle to deliver supercharged ingredients

Why We Use Serums As Our Product Base?

Day 0

Example Of Peptide Serum Results

Week 1

Week 3

Understanding Serums

Serums do not clog pores

Serums are generally selected to achieve a very focused result such as wrinkle reductions

They generally offer a single or limited action verses other products which use more ingredients at lower concentrations to try to tackle a large number of actions

Serums are designed to penetrate and not act as a moisturizing barrier therefore, clients with dry skin should apply a moisturizing layer after the serums have absorbed

Improvement Using Plant Stem Cells

!"#$%&'"'()*+,)'$*-./0*123*

4',%$'*-./0*53*67'*%,*%6$*8)'"*9'::*;<*

SerumsSerums often seem miraculous because they show some of their beneficial results almost immediately and the visible changes can be very dramatic

Serums can be used by any age client from teen to adult

Serums can be matched to various skin types and conditions through ingredient selection

Serums vs Moisturizers

Moisturizers use ingredients with larger molecular

lipids topically and create a moisture barrier

Moisturizers leave a fine film on the surface of the skin whereas serums deliver their ingredients deeper into the tissue

Serums use more active ingredients which are targeted to change the characteristics of the skin

Once our serums have been absorbed a moisturizer can be applied if needed

Ingredient Categories

Natural Earth Harvested IngredientsNatural Lab Constructed IngredientsLab Synthesized Synthetic IngredientsAnimal Derived IngredientsBases For Creams And SerumsDelivery SystemsActive vs Inactive IngredientsPreservatives

Natural Earth Harvested Ingredients

Natural earth harvested ingredients include:Standardized botanicals, organics and wild crafted botanicalsExtracts, Essential Oils, PureesHerbsMinerals

Ingredients in their naturally harvested state are often notwell absorbed topically due to large molecular sizes andmay not be concentrated or specific enough to producenoticeable positive results on the skin

It is difficult to formulate sophisticated 100% organicproducts that can achieve our performance goals, but theuse of some organic ingredients can be a marketingadvantage

Natural Lab Constructed Ingredients

Natural lab constructed ingredients are copiedin the lab, on a molecular level, to mirror nature

Organic chemists build identical molecularreplicas of earth-natural ingredients except thatthey screened and designed to focus on aparticular function which will yield the targetedresults we are seeking

This includes many peptides, other aminoacids, vitamins, some anti-oxidants etc.

Most of our ingredients fit this category

Peptide Synthesis MethodologyGenerally a biomedical researcher willexplore the possibility of increasing thenative potency or performancecharacteristics of a given substance,such as a peptide.

Small amounts of the peptide are used.The amino acid chain is manipulated toachieve the desired characteristics,activity, potency.

A larger scale of the synthesis is thencreated in order to initiate studies.

Upon successful validation, a largerscale production synthesis is completed

Lab Synthesized Synthetic Ingredients

These are substances that are formulated or manufactured by a chemical process or by a process that chemically changes a substance extracted from naturally occurring plant, animal, or mineral sources, except that this does not apply to substances created by naturally occurring biological processes

These ingredients are specifically designed to perform a targeted function

Animal Derived Ingredients

Animal derived ingredients are chosen by most cosmetic manufacturers to produce certain results

Examples of this would be: albumen, whey, marine oils

Our products are never tested on animals

Bases For Creams And Serums

Base ingredients such as fattyalcohols, waxes, acids, fixatives,humectants, coloring, scents,binding, stabilizing and gellingagents help the formulator achievecertain characteristics in creamsand to a lesser extent serums.

Bases contribute to viscosity,moisturization, texture, feel, andhelp to bind certain ingredients tomake a smooth emulsion.

Delivery Systems

to a carrier such as a liposome

If your high-tech ingredient does not reach the intended target in the body it will not respond as intended

Our products rely on increasingly sophisticated delivery systems to put active materials exactly where they are needed most

Enhanced skin delivery enables our formulators to achieve targeted and timed release of actives and enhance the efficacy and delivery of the effective concentration at the required site of action

Enhancing penetration, makes the right delivery system critical in formulating hard-to-use ingredients

peptides, hyaluronic acid, vitamin C and other vitamins, collagen and essential fatty acids as well as many other ingredients

Active vs Inactive IngredientsAn active ingredient, is biologically active , it makes changes in the tissue or actsa catalyst for the body to act in a pre-determined way. It is responsible forproducing a desired effect. It gives the product its main characteristics

Materials that work physiologically within the skin or aid in protecting the skinfrom insult are also called active ingredients. Although a cosmetic, by legaldefinition, can only serve to beautify and protect the surface of the skin, manycosmetic products can be shown to penetrate the dermal layers of the skin toexact a physiological change. One must be careful to market only beautifyingaspect of a product

Peptides are an example of an active material They have the ability to penetratethe skin, where they can increase the production of collagen, elastin, andintracellular substances thus improving the appearance of the skin

Thousands of cosmetic actives are used to affect the skin in a variety of ways.Some are used to lighten, tighten, and firm the skin

Inactive ingredients are considered biologically inert and may serve as:the bases forming the products solution, waxes, emollients, coloringagents, fillers, diluents, preservatives, solvents, lubricants, etc.

Most skin care products contain primarily in-active ingredients and add only afew select active ingredients at low concentrations. Our products contain 95%-99% active ingredients, these are the highest concentrations in the market.

EmulsionsThe majority of creams and lotions are emulsions

liquid is dispersed as fine droplets in the other making it homogeneous

Homogenized milk is an example of a typical oil-in-water (o/w) emulsion. Using an emulsifier called sodium caseinate

The majority of emollients used in personal care and beauty items are fats and oils, also called lipids.

Some of the key characteristics required in good emollients are good spreading properties, low toxicity/skin irritation and good oxidative stability.

SurfactantsMost emulsifiers can be considered surfactants or surface-active agents.These materials are able to reduce the surface tension of water.Example: Washing a greasy pan (fat) is easy with soap, because thesoap (surfactant), binds to the oil, and emulsifies with the water, it pullsthe grease off of the pan.

Fatty acids that are reacted with an emulsifier can form soaps. Theprocess of soap formation is called saponification. The negativelycharged stearic acid group is the main emulsifying unit of the soap, givingit the anionic classification. Positively charged emulsifiers are calledcationic.

Nonionic emulsifiers are often used in skin-care emulsion for their safetyand low reactivity. Glycerin, commonly added to cosmetic emulsions forits humectant properties, is the backbone of a class of emulsifiers calledGlyceryl esters .

Stearic acid is a major component of many of the fats and oils used inbeauty treatments, stearate-based emulsifiers are particularly useful.Fatty acids are key components of many cosmetic emulsifiers due theirmiscibility in a variety of natural and synthetic oils.

Esters polyethylene glycol or ethylene glycol are called PEG esters. APEG ester's solubility is determined by the number of PEG moleculesreacted per molecule of acid. In a formulation, are typically usedfor slip and feel.

MoisturizersThe main distinction between moisturizers and emollients is their solubility in water. Healthy skin requires moisture. Moisturizers are generally polar materials that are hygroscopic in nature; they hold onto water

Glycerin is a very cost-effective ingredient used to help reduce transdermal water loss

Sorbitol, sucrose, glucose, and other sugars are also commonly used to hydrate the skin

Aloe, which contains a mixture of polysaccharides, carbohydrates, and minerals, is also an excellent moisturizer

Moisturizers lay on the surface of the skin and act as a protective barrier. But as a barrier they may block the penetration of other useful (ie. peptides) ingredients that need to reach deeper tissue levels to work

Waxes/ThickenersWaxes

Waxes are composed primarily of long-chain esters that are solid at room temperature. Common waxes used in cosmetics are beeswax, candelilla, carnauba, polyethylene, emulsifying, and paraffin.

Waxes function as structuring agents, adding rigidity and barrier properties. By combining waxes with different properties you can add shine, flexibility, and brittleness

Waxes are particularly useful in hand creams and mascara emulsions for their thickening and waterproofing properties.

Thickeners

By incorporating enough wax into a thin lotion, a thick cream can be formed. Many thickeners are polymers. Cellulose, swells in hot water creating a gel network. Carbopol, a polyacrylic acid, swells when neutralized. Carrageenan, pectin, and locust bean gum are also all examples of cosmetic thickeners

PreservativesMost cosmetic products require the addition of preservative to prevent microbial contamination and rancidity

Parabens and ester of parabenzoic acid are by far the most commonly used because of their effectiveness against gram-positive bacteria. We do not use this group of preservatives.

Phenoxyethanol is used to protect against gram negative strains.

The cosmetic chemist will generally employ a mixture of preservatives to protect against different bacterial strains as well as yeasts and molds

Antioxidants such as tocopherol (vitamin E) and BHT are also often added to prevent oxidation of sensitive ingredients as well as protect the skin from free-radical damage

Shelf life and product preservation is important to consider when the dynamics of ordering , stocking and distribution are being determined

Efficacy, safety , environmental acceptance and international compliance are all considered when we select a preservative

INCI NamesIngredients are required to be listed on labels in INCI compliant format

Ingredients are listed in quantity based descending order; listing the ingredient with highest concentration in the product first

INCI stands for the International Nomenclature Of Cosmetic Ingredients

an ingredient acceptable in both US and international markets

INCI names are a combination of scientific Latin names and the English counterpart. An example of Raspberry Extract would be Rubus Idaeus (Rasberry) Fruit Extract

Our Products

Our Products Contain 12 Peptides

12 Transforming Results

Dramatically Reduced Wrinkle Volume Substantially Reduced Wrinkle DepthSubstantially Reduced Wrinkle Density Improved Collagen Production Improved Elastin Production Improved TighteningImproved Firmness Dermal Substructure ReinforcedImproved SmoothnessImproved ToneTightened Pores Wrinkle Producing Muscle Contractions Inhibited

Our Peptides

1. Tripeptide-1 -restores collagen levels substantially. In vitro tests showedcollagen 1 and collagen IV synthesis of 128% (collagen I) and 81% (collagenIV) respectively after 15 days. Collagen III tripled, this form of collagen is themost abundant type found in young skin. Tripeptide-1 is a technicallyadvanced ingredient which renews the appearance of critical collagen fibersthus helping the body to rebuild the dermal structure. Study showed a 29%wrinkle depth reduction in 30 days.

2. Palmitoyl Oligo Pentapeptide- It stimulates the production of collagen andfibronectin . Studies have shown collagen synthesis improved 117%,Collagen IV synthesis was improved by 327% and hylauronic acid synthesisincreased by 267%. Wrinkle reduction 68%-90%.

3. Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) -Mimics apeptide found in the venom of the Temple Viper. It was designed asneuromuscular blocking compound acting at the post-synaptic membrane asa reversible block that prevents acetylcholine from binding to the receptor.One study demonstrated a 52% reduction in forehead wrinkles.

4. Acetyl Hexapeptide-8 (Argireline) -Mimics the N-terminal end of Snap-25which competes for a position in the SNARE complex. When the SNAREcomplex is interrupted the vesicle release the neurotransmitters thatcause the muscle contractions which form a wrinkle. Studies showed wrinkledepth reduction of 17% in 15 days and 32% in 28 days.

5. Pentapeptide-18 -Inhibits the release of acetylcholine across the neurosynapse. It keeps the neuron in a resting state which may interfere with themuscle contractions that form expression lines and wrinkles. In combinationwith Argireline studies show it reduces wrinkle depth of 25% to 47% within 28days.

Our Peptides

6. Acetyl Octapeptide-3 (SNAP-8) -Similar to Argireline but 30% more active. Decreases neuronal excitability by destabilizing the SNARE complex. Studies have shown wrinkle depth reduction by 63% in 30 days.

7. Palmitoyl Tripeptide-5 (SynCol) -collagen. Also provides skin firming and moisturizing. In vitro tests in human fibroblasts showed a 119% increase of collagen synthesis compared to the positive standard.

8. Pentapeptide-3 (Vialox) - It acts at the post-synaptic membrane blocking sodium ions. The result is that the muscles that form wrinkles stay relaxed. It inhibits muscle contractions by acting as an competitive antagonist at the AChR receptor.

9. Acetyl Tetrapeptide-5 Won the technology award in cosmetics in 2005. Enhances elasticity of the skin, and improves skin smoothness. It prevents collagen cross links from glycation elasticity loss and the formation of eye bags. It also helps to prevent liquid from accumulating and inhibits vascular permeability. In vivo tests of subjects ages 18-65 resulted in elasticity being improved by 30% in 30 days, puffiness was significantly reduced in 14 days and eye bags were reduced by 70% in 28 days. Dark circles under the eyes were also reduced.

10. Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks)- neuromuscular blocking compound acting at the post-synaptic membrane as a reversible block that prevents acetylcholine from binding to the receptor, resulting in no uptake of sodium ions. The effect is that it relaxes facial muscles, smoothes skin, and reduces the appearance of wrinkles. One study demonstrated a 52% reduction in forehead wrinkles.

Our Peptides

11. Tripeptide-10 Citrulline Restores collagen levels substantially. In vitro tests showed collagen 1 and collagen IV synthesis of 128% (collagen I) and 81% (collagen IV) respectively after 15 days. Collagen III tripled, this form of collagen is the most abundant type found in young skin. Studies showed a 29% wrinkle depth reduction in 30 days. This peptide maintains a long-lasting collagen function that will help to ensure the appearance of healthy youthful skin.

12. Hexapeptide-10 A peptide that promotes cell adhesion, growth and migration, regenerating the basal lamina. A study showed cell growth increased by 74.6%. In addition to promoting cell adhesion and migration it also helps with the formation of blood vessels, and improves microcirculation. Cell proliferation results in compacted epidermis which provides firmness.

High Performance Skin Care4ce Of Nature provides a revolutionary approach to skincare using a collection of powerful serums to promote youthful skin

The line includes 4 highly transformative, anti-wrinkle, peptide enriched medical grade serums that when layered form the treatment component of daily skin care regimen. Other serums in the line target a variety of skin problems

experienced producing results far beyond expectations

The studies in this slide series helps to demonstrate empirically the efficacy of our products

We Built Products With Real Substance

95%-99% of our ingredients in each product are active ingredients

Our most powerful ingredients are formulated in concentrations far above the levels found in competitive high-end products

Our ingredients are class leading with award winning process technology

All ingredients are sourced globally for their intensive performing characteristics

Transforming Innovative Ingredients Into Marketable Products The Advantage Is Yours

We broke away from conventional thinking to build our products with real substance and stunning results

Our highly responsive products can be private labeled to position your organization for growth

Our skincare system is powerful enough to build your business by bringing customers back to you monthly, with their friends in tow as referrals wanting to try these products

Why We Are Unique?A Clinical Approach To Skincare

We took a clinical approach to the design of our products. Our lead formulating chemist is also a biologist

She along with our team of physicians approach the formulation process by analyzing the physiologic processes of the body that are compromised

She looks at the cellular processes and selects ingredients that act to

own repair mechanisms

The skin care industry is notorious for selling low concentration, high profile ingredients that are minimally effective and highly profitable

We took a different approach. We first consider the problem to be solved and the bodies physiology before ingredients are matched to solve the issue

Our ingredients are selected for their targeted functions, as well as the magnitude of their force and ability to correct the issue we identified

Secret Formulation TechniquesWe use closely held secret formulation techniques

They took several decades to develop

These techniques improve bioavailability, absorption, intensify action, improve penetration, assist to transfer material to the targeted cells, increase the results and shorten time of response

These processes are what make us unique and give our products a dramatic performance edge

Process engineering and unique ingredient sources makes our products impossible to duplicate without our formula, giving you one of a kind products

Bio-Vectored Formulas

We use bio-vectors to:

Identify the depth of delivery

Minimize the molecular size and use bonding to

enhance penetration

Achieve a high magnitude of impact and results

Improve the immediacy of the solution

Target the functional component in the transfer of

supercharged ingredients to targeted areas

Our Highly Skilled Development Team

Responsive scientific team with expertise in:

Analytical Chemistry

Medicine (2 Physicians and a Nurse with Burn and Skin Care Expertise)

Biology

Microbiology

Pharmacology

Nutritional Supplementation

Cosmeceuticals

Process Engineering

Aesthetics (Para-medical Aestheticians)

ANTI- WRINKLE PEPTIDE SERUM -1oz The Most Targeted Peptide Enriched Product Available

Re-awakens the cellular regeneration process

Unique blend of eight powerful peptide ingredients

Peptides are the most powerful ingredients in the anti-aging wrinkle reducing arsenal

Reduces wrinkle volume, depth and density

Encourages the body to rebuild collagen and elastin for visibly younger skin

Process engineering and unique ingredient sources makes this product almost impossible to duplicate without our formula, giving you a one of a kind product

PEPTIDE SERUM INGREDIENTS

Tripeptide-1- patented active peptide that helps the body substantially restore collagen levels.

Subjects studied from ages 35 to 55 showed a 29% wrinkle depth reduction in 30 days

Palmitoyl Oligo Pentapeptide - only a limited number of labs have access to this peptide due to patent restrictions. Stimulates the production of collagen and fibronectin promoting extracellular matrix renewal and cell proliferation.An in vivo (human based) study resulted in:the surface area of the deep wrinkles decreases by 68%, and in some cases was reduced by as much as 90%" the density of the main furrows: decreased by 47%" the area of the moderate wrinkles: decreased by 51%" the mean area of the main wrinkle: decreased by 22%

Stimulated the synthesis of the extra-cellular Matrix in vitro and ex vivo to very different extents:Collagen I : +117% Collagen IV : +327% It also stimulates the production of glycosaminoglycans: +267%.

Palmitoyl Oligo Pentapeptide Peptide #2

Peptide #2, (one of twelve peptides used in our products) is a fragment of the C-terminal portion of collagen I

synthesis of collagen I, collagen III and fibronectin

It has a more marked impact on low-density cultures of fibroblasts than on higher density, confluent cultures

This is relevant because it is closer to aging skin, which has a reduced population of fibroblasts

Deep Wrinkles Reduced By 68%-90%

The surface area occupied by deep wrinkles was reduced by a mean of 68% over 6 months and in some cases was reduced by as much as 90%The density of the main furrows: decreased by 47%The area of the moderate wrinkles: decreased by 51%The mean area of the main wrinkle: decreased by 22%

The concentration of this peptide in our products ranges between 8-16 times greater than the concentration used in this study

Significant Reduction In Wrinkles

Before Peptide #2 Use

6 Months After Peptide Use

Focus Ingredients

Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) a neurotrasmitter blocker, relaxes facial muscles, smoothes skin, and reduces the appearance of wrinkles.One study demonstrated a 52% reduction in forehead wrinkles.

Acetyl Hexapeptide-8 (Argireline) - reduces the appearance of the depth of wrinkles caused by facial expressions.Studies showed wrinkle depth reduction of 17% in 15 days and 32% in 28 days.

Pentapeptide-18 - interferes with the formation of expression wrinkles.In combination with Argireline studies show it reduces wrinkle depth of 25% to 47% with in 28 days.

Acetyl Octapeptide-3 (SNAP-8) - reduces wrinkle depth from the expression areas of the face .Studies have shown wrinkle depth reduction by 63% in 30 days.

Palmitoyl Tripeptide-5 (SynCol) -product collagen.

Pentapeptide-3 (Vialox) - peptide that offers intensive wrinkle care. It reduces expression line wrinkles and relaxes muscles.

Acetyl Hexapeptide-8 (Argireline) Peptide #4

Peptide #4 was designed to reduce wrinkle depth caused by facial expressions (forehead and eyes)

It is a neuro-transmitter blocking peptide

It mimics the N-terminal end of Snap-25 which competes for a position in the SNARE complex

neurotransmitters that cause the muscle contractions which form a wrinkle.

Studies showed wrinkle depth reduction from use of this peptide, of 17% in 15 days and 32% in 28 days.

Silicone imprints were made for this study and measured by confocal profilometry

How It Works

Muscles are contracted when they receive neurotransmitters released from a nerve cell in a process known as neuronal exocytosis

The neurotransmitter involved is acetylcholine and it is released from a vesicle into the synapse

The process involves several proteins, channels and vesicles

The SNARE protein complex is essential for neurotransmitter release at the synapsis and mediates the final steps of exocytosis

It is a complex formed by three proteins: VAMP, Syntaxin and SNAP-25

This complex is like a cellular hook that captures vesicles (a process called docking) and brings them close to the membrane to enable their fusion

How It Works

Neuro-transmitter acetylcholine and it is released from a vesicle into the synapse

The SNARE protein complex is formed by 3 proteins, VAMP, Syntaxin, and SNAP-25 and it is essential for neuro-transmitter release at the synapse and mediates the final steps of exocytosis

Acting as cellular hook it captures vesicles and brings them close to the membrane to enable fusion

SNAP Bio-Chemical Mechanism

Botlinum Toxin ABotulinum Toxin A paralyses the muscle by selectively blocking acetylcholine release at the neuromuscular junction

BoNT-A cleaves the protein SNAP-25 irreversibly, and therefore the SNARE complex cannot assemble

The nerve signal cannot be relayed, the muscle cannot contract and it is paralyzed.

Destabilized SNARE Complex, Peptide #4

If the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitters. As a consequence, muscle contraction is attenuated and the muscle is relaxed

Peptide #4 is a mimic of the N-terminal end of SNAP-25 and it competes with the natural protein for a position in the SNARE complex, so it destabilizes its formation, without breaking any of its components

In Vitro Efficacy

Inhibition of glutamate releaseat mM concentrations is aclear indicator of the potentanti-expression wrinkle activityof the peptide.

Inhibition of glutamate releaseby depolarized neuron is avalidated cell assay formeasuring the potentialactivity of compounds on theinhibition of neuronalexocytosis.

Untreated neuron cultureswere used as a negativecontrol and cultures treatedwith Botulinum Toxin A (BoNT-A) were used as a positivecontrol

Two In-Vitro Tests Related To The Formation Of Wrinkles

Reduction in the depth of wrinkles up to 17% after 15 days with 10% Peptide # 4 solution

The depth of the furrow decreased a maximum value of 32% in 28 days with a cream containing 5% Peptide #4 solution.

The concentration in our formula is much higher

Another StudyThis peptide reduces the severity of wrinkles around the eyes, up to 17% after 15 days of treatment and up to 27% after 30 days of treatment

Objective:To determine the effectiveness of the peptide #4 cream in reducing the severity of wrinkles

Reduced wrinkle depth up to 27% in 30 days

Volunteer nº5 (38 years)

Base

Peptide 4

Volunteer nº3 (54 years)

Volunteer nº3 (54years)

Video Sequence

Volunteer nº7 (45 years)

Video Sequence

Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake)

A neuro-transmitter blocking Peptide

A small peptide that mimics the activity of a polypeptide found in the venom of a Viper Capable of reducing mimic wrinkles by inhibiting contractionsReduced forehead wrinkles by 52%

Ra: average roughnessRt: maximum difference between the highest peak and the deepest furrowsRz: mean value of these different maximaA decrease of the Ra expresses a smoothed reliefA decrease of the Rt and Rz expresses a decrease of wrinkle depth

Study On Smoothing And Anti-Wrinkle

Effect Of Peptide # 3

Wrinkles Decrease 52% On The Forehead

Measurements on Volunteer #29 showed that Peptide #3 was able to reduce forehead wrinkles by up to 52%

In vitro measurements showed that Peptide #3 (at a concentration of 0.5mM) was able to reduce the frequency of contractions of innervated muscle cells by 82% (p<0.05) after 2 hours of treatment

and anti-wrinkle effect on this area

Using the PRIMOS® technique, parallel stripe patterns are projected on the sample with successive phase shift.

The analysis of fringe deformations provided a qualitative and quantitative evaluation of each height profile

Wrinkle Height Profile

Acetyl Octapeptide-3 (SNAP-8) Peptide #6

A wrinkle reducing peptide that is similar to Argireline but 30% more active.

It reduces wrinkle depth from the expression areas of the face such as the forehead and eyes.

It decreases neuronal excitability by destabilizing the SNARE complex.

Studies have shown wrinkle depth reduction by 63% in 30 days.

Inhibition Of Snare Complex Formation

Demonstrates the blocking of SNARE complex formation. The lower the SNARE complex in vitro, the higher the efficacy of the anti-wrinkle cream.

Evaluated the antagonistic competitive efficacy of the peptide patterned after SNAP-25 N-Terminal domain compared to native SNAP-25(positive control). Peptide #6 has the capacity to assemble with syntaxin and synaptobrevin forming the SNARE complex, which was measured.

Heat and consequent thermal decomposition was the negative control

Modulation Of Glutamate Release In A Neuron Cell Culture

Glutamate is the most excitatory abundant neurotransmiter in the nervous system.

The release of glutamate in a primary cell culture of neurons was measured to compare the in vitro activitiy of Peptide 6 and Botulinum Toxin A (positive control)

Peptide #6 inhibits glutamate release in a dose-dependent manner

Peptide #6 Peptide #6

63% Reduction Value Of Wrinkle Depth With Peptide #6

Skin topography analyses were performed to measure the effectiveness of a cream containing 10% Peptide #6

Silicon imprints were obtained from around the eyes of 17 women volunteers pre-test and after the 28 day treatment.

Analyses of imprints were performed by confocal profilometry

Bonnie After Using The Peptide Serum

Day 0

Week 3

Stem Cell Serum

Using state of art technology to culture plant stem cells

Based on high-tech bioreactor plant cell culture technology, that was awarded the Innovation Award in 2008

First stem cell ingredient is from a rare apple, known for its longevityA study with our first ingredient with subjects between the ages of 37-64, showed a significant and visible decrease in wrinkle depth for 100% of the subjects by the 28 days. Study results showed that the CFE (colony-forming efficiency) was stimulated by 92% in the presence of 0.04% of the stem cell extract. This clearly showed an improved maintenance of the stem cell characteristics of epidermal stem cells.

Second plant stem cell ingredient is from a rare Gamay grape ,which has extremely high anthocyanins, this ingredient fights photo-aging and delays cell deathStudy results showed this stem cell extract to strongly increase CFE: the CFE was stimulated by almost 80% Clearly showing that it helps the epidermal stem cells maintain their stem cell characteristics.

Why Use Plant Stem Cells

Epidermal stem cells rejuvenate and promote the balance of cells in the skin and help to regenerate damaged tissue.

Aging reduces the number of stem cells in the skin and diminishes their ability to repair the skin.

Plant stem cells contain specific epigenetic factors that help to maintain the regeneration capacity of stem cells in the skin.

The result is a remarkable improvement in the appearance of the skin as well as a reduction in wrinkles, and protection against oxidative stress.

Focus Ingredients

Malus Domestica Fruit Cell Culture - Awarded the Innovation Award in 2008. It uses a liposomal delivery system and is based on plant stem cells from an endangered fruit(apple) that is known for its longevity. Studies have demonstrated its remarkable age delaying and anti-wrinkle effects in humans.

Palmitoyl Oligo Pentapeptide - Promotes collagen helps to improve the visible signs of aging.

Vitis Vinifera (Grape) Fruit Cell Extract - Plant stem cells contain specific components, called epigenetic factors. They regulate the activity and the function of the cell. These plant stem cells improve the vitality of skin stem cells, and protect them against negative environmental influences

Improvement Using Apple Stem Cell

Before (day 0) of use of our Apple Stem Cell

After (day 28)

TIGHTENING SERUM- 1 ozReduce The Appearance Of Loose Skin And Enlarged Pores

Contains peptides designed to help you look younger by increasing the elastin and collagen in your skin

Reduces the appearance of loose skin and improves the skins resilience

Improves cell proliferation resulting in a more compacted epidermis which provides firmness

Provides a noticeable tightening effect, strengthens connective tissue, and provides protection against oxidative stress.

Focus Ingredients

Tripeptide-10 Citrulline - A peptide that substantially restores collagen levels.Showed a 29% wrinkle depth reduction in 30 days. This peptide maintains a long-lasting collagen function.

Pullulan - An anti-oxidant that also helps to retain moisture.

Hexapeptide-10 - A peptide that promotes cell adhesion, growth and migration, regenerating the basal lamina. Tests have been carried out to quantify the increase in cellular adhesion of keratinocytes and fibroblasts.A study showed cell growth increased by 74.6%.

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (syn-taks) - It helps to restore the structural integrity of the skin, reducing wrinkles, and improving tone.

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks) - It helps to restore the structural integrity of the skin, reducing wrinkles, and improving tone.

Enteromorpha Compressa Extract - An edible form of green algae that produces a large array of bioactive compounds found useful in the treatment of inflammation, allergies and bacterial and viral infections.

Theobroma Cacao(Cocoa) Extract Provides anti-oxidant and anti-stress effects for skin preparations. Acts as a skin balancer and energizer reducing cell degeneration and protecting the skin from cell damage.

PEPTIDE EYE SERUM-! ozAward Winning Ingredients Used In This Powerful Peptide Serum

Exciting powerful eye serum using award winning ingredients.

This product provides dramatic reductions in baggy eyes, dark circles, fine lines and wrinkles.

Returning the skin to a much more youthful state.

Focus Ingredients

Acetyl Tetrapeptide-5 - Won the technology award in cosmetics in 2005.

In vivo tests of subjects ages 18-65 resulted in elasticity being improved by 30% in 30 days,puffiness was significantly reduced in 14 days and eye bags were reduced by 70% in 28 days. Dark circles under the eyes were also reduced.

Acetyl Octapeptide-3 (SNAP-8) It reduces wrinkle depth from the expression areas of the face such as the forehead and eyes. It decreases neuronal excitability by destabilizing the SNARE complex. Studies have shown wrinkle depth reduction by 63% in 30 days

Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) - A wrinkle reducing active peptide that mimics a peptide found in the venom of the Temple Viper. It was designed as neuromuscular blocking compound acting at the post-synaptic membraneOne study demonstrated a 52% reduction in forehead wrinkles.

EYE LASH LENGTHENER 10mlWe Broke From Conventional Thinking When This Product Was Designed

Unparalleled combination of class leading formulation processes and performance based ingredients

Uses Keratinocyte Growth Factor partnered with a variety of powerful ingredients that benefit the follicles ability to add new hair.

We set the stage by improving the environment for growth and then added the trigger that makes it happen.

Focus IngredientsL-Acetyl Carnitine - Reactivates the hair follicles. Transfers fatty acids to the

mitochondria to be used as energy and to enhance active metabolism needed for cellular repair.

Niacinamide - An anti-inflammatory and vasodilator. It stimulates collagen and acts as an anti-oxidant. It reduces inflammation.

Soy Isoflavones - Helps preserve elasticity limiting the breakage of hair.

Saw Palmetto Extract - Thought to block cell receptor sites required to absorb DHT. May improve hair growth, maintains healthy hair and helps to reverse hair loss.

Keratin - Primary constituent of hair it wraps the hair follicle with a keratin bond that protects and strengthens the hair shaft.

Nettle Extract - Partially blocks 2 enzymes, 5a-reductase, which makes dihydrotestosterone (DHT) and aromatase enzyme. These enzymes are thought to block hair growth.

Hexanoyl Dipeptide-3 Norleucine Acetate: - A peptide that activates follicle regeneration.

Focus IngredientsLecithin- A natural emulsifier and lubricant. It also protects cell follicles from

oxidation and breakdown.

L-Arginine - An amino acid that may bring oxygen to the tissue. It may act on the follicle by promoting the formation of L-proline, an amino acid that is essential to the synthesis of collagen. It is thought to play a role in cell division.

L-Glutamine - An amino acid that helps with cell rejuvenation. Acts as an eye tissue nutrient.

Zinc - Benefits cellular growth and appears to limit DHT production. It helps with absorption of vitamins and proteins that are necessary for hair growth and maintenance.

Keratinocyte Growth Factor (KGF) - A growth factor that promotes hair growth, it is synthesized by fibroblasts. A complex growth factor it contains an 160 amino acid chain that stimulates cell replication. This is made specifically for our product.

Superoxide Dismutase - An enzyme that prevents oxidative stress and enhances antioxidant balance. SOD is found in the dermis and epidermis and is important in the production building new cells.

LIGHTENING SERUM 1 ozRevolutionary Serum Significantly Lightens And Reduces The Appearance Of Skin Discoloration

An aesthetic treatment that significantly reduces the appearance of skin discoloration and lighten and brightens the appearance of the skin.

Each individual responds differently to ingredients, we approached this issue by using ten distinctly different skin lightening ingredients.

Each ingredient operates in a slightly different way to ensure that the outcome will be what you expect.

Focus Ingredients

Diaminopropionoyl Tripeptide-33 - A peptide that reduces the appearance of photo-aging. It promotes the DNA repair systems capacity, and provides the skin protection from aging.

Arbutin - Arbutin has a depigmenting effect on the skin. Increases cutaneousluminosity, cutaneous smoothness, with a significant reduction of cutaneoustint, and cutaneous dyschromia.

Inhibits the tyrosinase enzyme and has been documented by in vitro studies to have an enzymatic inhibition level of 56%.

Kojic Acid - An effective skin lightener, inhibits melanin production, helps to balance skin tones, fading dark spots and freckles caused by sun exposure, aging, and cutaneaous hyper-pigmentation.

Licorice Root - A skin whitener, anti-inflammatory, anti-microbial and anti-oxidant.

Magnesium Ascorbyl Phosphate - It significantly affects the appearance of skin lightening acting to inhibit tyrosinase to reduce the formation of melanin. It also promotes collagen synthesis.

Focus Ingredients

Bellis Perennis (Daisy) Flower Extract - Highly efficient natural skin lightener by influencing melanin formation.

An in vitro study done in the Philippines showed a reduction of tyrosinase and tyrosinase activity resulting in a significant lightening effect.

Diacetyl-Boldine - A skin lightener, was shown to be 30 times more effective than kojicacid. In vitro tests showed it inhibited the activity of tyrosinase by 56%. A study of Asian subjects showed skin lightening improved by 71%, hyper-pigmented areas decreased by 54%, complexion was viewed as 65% move even, and 74% more radiant. A study of Caucasian subjects showed a 23% reduction in age spots. It provides the skin with an even, luminous and mat complexion.

1-aminoethylphosphinic acid - Used as a skin lightener to reduce age spots. Acts different from tyrosinase inhibitors, it slows down melanogenesis providing a whitening effect by decreasing melanin systhesis at the DOPA-Chrome level

Dimethylmethoxy Chromanyl Palmitate - Provides considerable skin lightening. A study of Asian women ages 18-46 showed a 37% inhibition of tyrosinase activity, it stopped endogenous tyrosinase activity by 43% and was found to have a better di-pigmenting effect than Kojic acid.

CELLULITE CREAM 5 ozFinally A Solution That Actually Works

This intensely effective approach to lustrous, youthful, smooth skin, reduces the appearance of cellulite.

A Brazilian study of 99 women showed more than

88% experienced a decreased circumference their thighs and arms 68% saw an additional reduction of their hip size when the caffeine ingredient was analyzed.

Pseudoalteromonas Ferment Extract study showed

128% increase in collagen 1 within 15 days81% increase in type IV collagen

Focus Ingredients

Lecithin - May reduce the accumulation of fluids, reduce inflammation and improve circulation. Helps the body improve the support structures under skin to keep cellulite from showing through.

Caffeine - Vasoconstrictor, reduces fluid retention and may improve fat metabolism.

Butcherbroom (Ruscus Aculatus) Root Extract - Decreases excess fluids, anti-inflammatory.

Tea-Hydroiodide - Is a skin conditioning agent.

Ivy (Hedera Helix) Extract - Tones, tightens and helps reduce build up of waste products in tissue.

Carnitine - A naturally occurring amino acid supports the transport long chair fatty acids to the mitochondria where it is used for energy. Thought to improve appearance of dimpled skin.

Tripeptide-1 - A patented peptide that acts as a skin conditioning agent.

Panthenol - Provitamin B5 has the effect of filling in areas and stretching the skin.

Focus Ingredients

Marrubium Vulgare Extract - An anti-inflammatory that assists in absorption.

Pseudoalteromonas Ferment Extract - A glycoprotein found at the bottom of a glacier in Antartica, it is

thought to increase elastin and collagen.

One study showed a 128% increase in collagen 1 within 15 days and a 81% increase in type IV collagen.

Acetyl Tetrapeptide-5 - A peptide that reduces edema in tissue.

Pentapeptide-18 - A neuropeptide that helps to relax muscles and tighten the skin.

Rucus Aculeatus Root Extract - Improves microcirculation in the skin, and capillary permeability.

Citrus Medica Limonum Peel Extract - Benefits circulation and helps improve blood flow.

Solidago Virgaurea Extract - Improves circulation, contracts tissue, reduces fluids.

Astragalus Membranaceus Root Extract - Benefits micro-circulation, firms and smoothes the skin and

helps to reduce the appearance of imperfections.

Ilex Paraguariensis Leaf Extract(Yerba Mate) - Has a relaxing effect on muscle tissue, burns fat.

Cameilia Oleifera Extract(Green Tea) - Rich in anti-oxidants and anti-inflammatory properties.

Cola Acuminata Seed Extract - Provides the stimulating and fluid draining effects of caffeine. Improves

texture on uneven dimpled skin.

Japanese Pepper Extract: - A pepper that results in a hot or tingling sensation to the skin. It is an anti-

oxidant that also benefits microcirculation. Anti-inflammatory.

FACIAL/BODY HAIR INHIBITOR 1 ozDramatically Reduce The Appearance Of Unsightly Hair

Hair growth cycles can take 3-4 months with 80% of your hair in a growth cycle at any one time.

Most cultures dictate the aesthetic level of hair for both men and women and social acceptance is affected for those who violate those norms.

It effectively helps to dramatically reduce the appearance of unsightly hair

A study on one of our key ingredients showed a decrease of 30% in hair length and a 16% reduction in density within 60 days.

Focus Ingredients

Larrea Diviaricata Extract - A hair growth inhibitor that also has anti-oxidant and anti-microbal properties.

Lauryl Isoquinolinium Bromide - A major hair growth inhibiting ingredient. It decreases the length and density of hair, reduces the need for shaving or depilation. It targets the hair follicle cells and decreases new hair formation. One study showed a decrease of 30% in hair length and a 16% reduction in density within 60 days.

Pseudoalteromanoas Ferment Extract - It maintains natural bio-protective properties and promotes keratinocyte growth and fibroblast adhesion for a skin regenerating effect.A study showed increased collagen I synthesis by 81% after 7 days and 128% after 15 days and increased collagen IV synthesis 36% after 7 days and 81% after 15 days.

Subtilisin - A keratinolytic protease that invades the hair structure and causes proteolytic cleavage which reduces intercellular adhesion and reduces hair growth. It also diminishes the size of hair follicles and hair shafts.

Palmatine - Slows mitosis and therefore reduces hair growth.

New Products

Roll Off Wrinkles A strong peptide formula that comes in bottle with a roller ball. It can be carried in your pocket or purse and used throughout the day. It is particularly designed to eliminate the more difficult wrinkles

Anti-Oxidant Serum A serum loaded with anti-oxidants that will protect the skin from free radical scavengers, nourish and revitalize it

Telomer Protect Serum - The discovery of telomeres won the 2009 Nobel Prize in

youthful cell function. Every time your cells divide, your telomeres shorten. When your telomeres become too short, cell division stops and your cells can no long divide to build new cells. This product helps maintain telomeres and extend the lifespan of your skin cells.

up your sagging skin

Inside Out Beauty Supplement Designed using three proprietary blends of the ingredients. The first is a powerful blend of amino acids which encourages the body to produce Human Growth Hormone. This hormone declines with aging and that loss results in a loss of energy, stamina, strength, muscle tone and skin tone, thickness and wrinkle formation. This blend can dramatically assist the body to achieve the vigor and characteristics of a more youthful state. The other two blends focus on adding anti-oxidants to the body to improve both health and beauty.

Nutritional Supplements

Why We Are Unique

We use the highest quality ingredients

We formulate using high concentrations of the most potent ingredients

We use semi-manual encapsulation processes to eliminate the need for excipents

We perform vendor audits, and all ingredients are tested for purity, potency, authentication

We participate in an extensive audit by an outside auditing company

We use the most cutting edge advancements to aging in recent history

An unparalleled approach to beauty and wellness

95%-99% of our ingredients in each product are active ingredients

Our formulation team includes physicians

Our formulations use clinical strengths of medical grade ingredients

All products are manufactured in house in our fully accredited manufacturing plant

Appetite Suppressant/Thermogenic

This appetite suppressant works by Diminishing appetite

Increases the sensation of fullnessImproves mood Helps to develop a perceived sense of happiness

Unlike other supplements this product approaches appetite suppression from many angles, and gives the body several opportunities to feel satiety.

It acts as a thermogenicburning of fat.

It is caffeine, and ephedra free.

It controls appetite during times of boredom or emotional distress.

WEIGHT LOSS CARBOHYDRATE CONTROL - 180 capsThe Help You Need To Control Carbs

Helps to break the vicious weight gain cycle and control carbohydrate cravings.

Helps reduce the absorption of starchBreaks down carbs into absorbable sugarsHelps the body better regulate glucose and insulinImproves pancreatic function by mediating insulin releaseHelps the body better use calories and metabolize glucoseReduces carbohydrate cravingsStimulates the brain to feel satisfied and full

WEIGHT LOSS FAT BURNER (LIPOTROPIC) - 60 capsPower Up Your Ability To Burn Away Fat

This supplement helps to:Control appetite and improve moodBreakdowns fat and converts it to energyRemoves and metabolizes excess fat from the liver

its effect on fat storage

formation on arterial walls

NATURAL HAPPINESS 60 capsRenew Your Sense Of Joy, Re-energize Your Life

A non sedating formula that helps maintain and elevate mood levels

Combats fatigue

Increases energy levels and improves malaise

Helps minimize depression and relieve tension, irritability, stress and anxiety

Improves memory

LIVER SUPPORT 180 capsIs Your Liver Working Overtime? What Are You Doing To Protect It?

Aids in liver detoxification

Improves digestion

Enhances bile production and flow

Assists in neutralizing and eliminating toxins, provides anti-oxidant benefits

Helps protect the liver from damage and supports its optimal functioning

MENOPAUSE SYMPTOM RELIEF 60 capsLive Comfortably As Menopause Approaches

Improves menopause symptoms

Helps regulate mood swings

Helps regulate hormonal swingsReduces hot flashes and night sweats

Minimizes weight gain

Improves bladder incontinence and overactive bladder

JOINT SUPPORT 480 gramsReduce Pain, Swelling, Tenderness And Stiffness

Helps build synovial fluid and cartilage

Improves mobility and reduces discomfort

Improves health and function of cartilage

Reduces pain, swelling, tenderness and stiffness

Improves athletic recovery

MUSCLE CRAMP OIL 4ozStop Painful Sudden Forceful Muscle Cramps

Helps restore magnesium levels in the body

Helpful to athletic recovery

Helps relieve aches, pain, muscle cramps, and stiffness

Helps maintain muscle function

Calms nerves

Supports restful sleep

Highly absorbable without GI side effects common with oral version and acts quickly

Q IMMUNE 120 capsAn Unprecedented Approach To Immune Support

The discovery of the biologic importance of our key ingredient Germanium has been touted as a landmark development in the field of nutritional and metabolic medicine

Dramatically improves the efficiency of oxygen utilization at a cellular level

Each atom of germanium is bonded to three atoms of oxygen, making it an efficient carrier of oxygen, it is believed oxygen cannot be properly metabolized by cancer cells

Powerful regulator of the immune system, activating an under-active system and suppressing over-activity when necessary

Our unique proprietary engineered blending process transforms this combination of ingredients and dramatically enhances their

effectivenessbioavailability provides a compounding effect with the supporting ingredients

4ce Of Nature and one of a kind.

technology, and process engineering as we transform our secret processes and a set of incredibly responsive ingredients, into highly responsive products.

ever experienced Producing rapid and stunning changes to the skin Transforming tired, aged, wrinkled skin into vibrant youthful restored skin Protecting younger skin from the ravages of aging

4ce Of Nature

Using highly concentrated peptide enriched formulas our products produce astounding results.

Nothing currently on the market comes close to our products performance

Process engineering offers our products a unique edge and protects against competitors attempts at duplication

Small molecular sizes allow deep penetration

Unique delivery systems maximize absorption

Careful PH balancing help our products to penetrate deeper and respond faster